Mus musculus

87 known processes

Socs2

suppressor of cytokine signaling 2

(Aliases: SOCS-2,Cish2,MGC118106,AI527257,D130043N08Rik,CIS2,AW108012,8030460M17,SSI-2,JAB,hg)

Socs2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.653
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.610
regulation of insulin receptor signaling pathway GO:0046626 21 0.487
Mouse
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.473
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.450
cerebral cortex radially oriented cell migration GO:0021799 31 0.424
Mouse
cerebral cortex radial glia guided migration GO:0021801 17 0.410
Mouse
multicellular organism growth GO:0035264 161 0.368
telencephalon development GO:0021537 186 0.364
Mouse
gland development GO:0048732 330 0.357
cellular response to amino acid stimulus GO:0071230 29 0.355
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.348
regulation of activation of jak2 kinase activity GO:0010534 1 0.338
Mouse
forebrain development GO:0030900 302 0.330
Mouse
regulation of activation of janus kinase activity GO:0010533 1 0.324
Mouse
negative regulation of phosphorylation GO:0042326 166 0.319
Mouse
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.314
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.289
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.289
g protein coupled receptor signaling pathway GO:0007186 243 0.287
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.282
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.280
Human Mouse
forebrain cell migration GO:0021885 58 0.268
Mouse
inflammatory response GO:0006954 244 0.267
Mouse
regulation of transferase activity GO:0051338 263 0.266
Mouse
cellular amino acid metabolic process GO:0006520 103 0.265
positive regulation of kinase activity GO:0033674 155 0.264
Mouse
amine metabolic process GO:0009308 45 0.261
embryonic placenta development GO:0001892 98 0.256
Mouse
cellular response to peptide GO:1901653 92 0.255
Human Mouse
renal system development GO:0072001 225 0.251
negative regulation of protein metabolic process GO:0051248 282 0.247
Mouse
cytokine production GO:0001816 319 0.243
Mouse
jak stat cascade GO:0007259 42 0.242
cellular ketone metabolic process GO:0042180 84 0.236
pallium development GO:0021543 120 0.232
Mouse
activation of janus kinase activity GO:0042976 2 0.229
Mouse
morphogenesis of a branching structure GO:0001763 203 0.221
Mouse
response to organonitrogen compound GO:0010243 246 0.204
Human Mouse Rat
regulation of cellular amine metabolic process GO:0033238 20 0.198
kidney development GO:0001822 213 0.194
regulation of defense response GO:0031347 233 0.194
Mouse
regulation of secretion GO:0051046 274 0.192
Mouse
telencephalon cell migration GO:0022029 55 0.191
Mouse
regulation of cell migration GO:0030334 219 0.187
adaptive immune response GO:0002250 155 0.186
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.185
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.183
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.183
urogenital system development GO:0001655 261 0.182
hindbrain radial glia guided cell migration GO:0021932 12 0.177
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.177
negative regulation of inflammatory response GO:0050728 61 0.176
Mouse
radial glia guided migration of purkinje cell GO:0021942 6 0.175
Mouse
regulation of protein localization GO:0032880 231 0.172
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.172
Mouse
negative regulation of defense response GO:0031348 77 0.171
Mouse
cerebral cortex cell migration GO:0021795 44 0.171
Mouse
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.171
Mouse
peptidyl amino acid modification GO:0018193 336 0.169
Mouse
positive regulation of nervous system development GO:0051962 221 0.166
peptidyl tyrosine modification GO:0018212 145 0.163
Mouse
response to peptide GO:1901652 136 0.161
Human Mouse Rat
positive regulation of programmed cell death GO:0043068 218 0.158
morphogenesis of a branching epithelium GO:0061138 193 0.155
Mouse
regulation of kinase activity GO:0043549 249 0.153
Mouse
positive regulation of cell development GO:0010720 237 0.152
leukocyte differentiation GO:0002521 342 0.150
Mouse
placenta development GO:0001890 140 0.150
Mouse
epidermal growth factor receptor signaling pathway GO:0007173 28 0.146
Mouse
regulation of t cell activation GO:0050863 170 0.145
Mouse
regulation of lymphocyte activation GO:0051249 240 0.144
Mouse
blood vessel morphogenesis GO:0048514 285 0.141
positive regulation of protein modification process GO:0031401 299 0.141
Mouse
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.138
Mouse
cell type specific apoptotic process GO:0097285 268 0.133
positive regulation of transferase activity GO:0051347 167 0.132
Mouse
regulation of mapk cascade GO:0043408 248 0.132
hindbrain development GO:0030902 128 0.132
Mouse
mapk cascade GO:0000165 281 0.130
negative regulation of molecular function GO:0044092 258 0.129
Mouse
homeostasis of number of cells GO:0048872 210 0.128
protein modification by small protein conjugation GO:0032446 187 0.126
Mouse
negative regulation of growth GO:0045926 99 0.125
glucose homeostasis GO:0042593 128 0.124
response to growth factor GO:0070848 198 0.123
regulation of secretion by cell GO:1903530 249 0.123
Mouse
ossification GO:0001503 216 0.123
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.121
Mouse
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.119
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.118
Human Mouse
positive regulation of cell activation GO:0050867 158 0.118
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.117
kidney epithelium development GO:0072073 121 0.116
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.113
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.112
Mouse
cd4 positive alpha beta t cell activation GO:0035710 45 0.112
Mouse
fat cell differentiation GO:0045444 160 0.112
Mouse
negative regulation of protein modification process GO:0031400 163 0.112
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.109
Mouse
labyrinthine layer development GO:0060711 49 0.109
Mouse
regulation of homeostatic process GO:0032844 182 0.106
spongiotrophoblast layer development GO:0060712 15 0.104
Mouse
regulation of tyrosine phosphorylation of stat1 protein GO:0042510 2 0.103
Mouse
skeletal system development GO:0001501 356 0.102
erk1 and erk2 cascade GO:0070371 77 0.101
t cell differentiation GO:0030217 174 0.099
Mouse
leukocyte activation involved in immune response GO:0002366 126 0.098
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.097
positive regulation of cell death GO:0010942 224 0.097
regulation of inflammatory response GO:0050727 147 0.096
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.096
Mouse
protein ubiquitination GO:0016567 171 0.096
Mouse
respiratory system development GO:0060541 190 0.095
negative regulation of cell proliferation GO:0008285 296 0.092
cellular amine metabolic process GO:0044106 44 0.091
negative regulation of t cell activation GO:0050868 65 0.091
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.090
Mouse
neuron apoptotic process GO:0051402 142 0.090
protein secretion GO:0009306 111 0.089
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.089
t cell activation GO:0042110 289 0.089
Mouse
camera type eye development GO:0043010 266 0.086
myeloid cell differentiation GO:0030099 233 0.086
response to peptide hormone GO:0043434 127 0.086
Human Mouse Rat
regulation of lymphocyte differentiation GO:0045619 107 0.086
Mouse
cerebral cortex development GO:0021987 86 0.085
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.084
Mouse
lactation GO:0007595 25 0.083
mammary gland lobule development GO:0061377 22 0.082
placenta blood vessel development GO:0060674 31 0.080
Mouse
regulation of organ morphogenesis GO:2000027 144 0.080
gliogenesis GO:0042063 141 0.080
negative regulation of cellular component organization GO:0051129 194 0.079
peptidyl tyrosine phosphorylation GO:0018108 143 0.079
Mouse
cell adhesion GO:0007155 329 0.079
negative regulation of immune system process GO:0002683 209 0.078
Mouse
response to acid chemical GO:0001101 111 0.078
Mouse
regulation of cell motility GO:2000145 236 0.078
positive regulation of mapk cascade GO:0043410 170 0.078
regulation of response to wounding GO:1903034 189 0.077
Mouse
epithelial tube morphogenesis GO:0060562 303 0.077
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.076
Mouse
regulation of cytokine production GO:0001817 266 0.076
Mouse
muscle tissue development GO:0060537 308 0.076
regulation of anatomical structure size GO:0090066 178 0.075
angiogenesis GO:0001525 201 0.074
cellular chemical homeostasis GO:0055082 215 0.073
lymphocyte differentiation GO:0030098 242 0.073
Mouse
regulation of neuron differentiation GO:0045664 281 0.073
positive regulation of apoptotic process GO:0043065 217 0.071
connective tissue development GO:0061448 179 0.071
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.070
Mouse
neural tube development GO:0021915 160 0.069
positive regulation of t cell differentiation GO:0045582 52 0.069
Mouse
negative regulation of transferase activity GO:0051348 85 0.069
defense response to other organism GO:0098542 197 0.068
male gamete generation GO:0048232 285 0.068
epithelial cell proliferation GO:0050673 174 0.066
respiratory tube development GO:0030323 167 0.065
alpha beta t cell differentiation GO:0046632 69 0.064
Mouse
regionalization GO:0003002 337 0.064
monosaccharide metabolic process GO:0005996 106 0.064
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.063
negative regulation of cell activation GO:0050866 111 0.063
Mouse
regulation of hydrolase activity GO:0051336 246 0.063
cellular response to peptide hormone stimulus GO:0071375 92 0.062
Human Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.061
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.061
Mouse
regulation of neuron apoptotic process GO:0043523 122 0.061
regulation of cell activation GO:0050865 289 0.060
Mouse
tyrosine phosphorylation of stat protein GO:0007260 23 0.060
Mouse
leukocyte proliferation GO:0070661 172 0.059
regulation of wnt signaling pathway GO:0030111 123 0.059
response to lipopolysaccharide GO:0032496 128 0.059
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.059
Mouse
negative regulation of leukocyte differentiation GO:1902106 51 0.059
Mouse
negative regulation of t cell differentiation GO:0045581 23 0.059
Mouse
neuron death GO:0070997 154 0.059
labyrinthine layer morphogenesis GO:0060713 21 0.058
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.058
positive regulation of leukocyte differentiation GO:1902107 86 0.058
Mouse
cell substrate adhesion GO:0031589 130 0.058
regulation of vesicle mediated transport GO:0060627 139 0.057
wnt signaling pathway GO:0016055 188 0.057
ribonucleotide metabolic process GO:0009259 291 0.057
t helper cell differentiation GO:0042093 28 0.057
Mouse
fertilization GO:0009566 127 0.056
positive regulation of cell migration GO:0030335 109 0.056
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.056
Mouse
glial cell differentiation GO:0010001 131 0.056
carbohydrate homeostasis GO:0033500 128 0.056
negative regulation of lymphocyte differentiation GO:0045620 32 0.054
Mouse
regulation of adaptive immune response GO:0002819 90 0.054
Mouse
lipid biosynthetic process GO:0008610 179 0.054
cellular lipid metabolic process GO:0044255 323 0.053
muscle cell differentiation GO:0042692 261 0.053
body fluid secretion GO:0007589 53 0.053
organonitrogen compound biosynthetic process GO:1901566 192 0.053
regulation of protein secretion GO:0050708 82 0.052
Mouse
heart morphogenesis GO:0003007 178 0.052
alpha beta t cell activation GO:0046631 91 0.052
Mouse
anatomical structure homeostasis GO:0060249 145 0.051
heterocycle catabolic process GO:0046700 280 0.051
immune effector process GO:0002252 321 0.050
Mouse
regulation of alpha beta t cell differentiation GO:0046637 35 0.050
Mouse
germ cell development GO:0007281 185 0.050
regulation of alpha beta t cell activation GO:0046634 53 0.049
Mouse
regulation of t helper 1 cell differentiation GO:0045625 7 0.049
Mouse
protein processing GO:0016485 163 0.049
t cell proliferation GO:0042098 120 0.048
cellular calcium ion homeostasis GO:0006874 119 0.048
purine containing compound metabolic process GO:0072521 311 0.048
purine ribonucleotide metabolic process GO:0009150 290 0.048
rhythmic process GO:0048511 174 0.047
regulation of cytokine secretion GO:0050707 61 0.047
Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.047
cellular homeostasis GO:0019725 240 0.047
development of primary sexual characteristics GO:0045137 143 0.047
regulation of protein kinase activity GO:0045859 232 0.047
Mouse
trophoblast giant cell differentiation GO:0060707 15 0.046
Mouse
nucleoside catabolic process GO:0009164 206 0.046
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.046
Mouse
embryonic epithelial tube formation GO:0001838 130 0.046
regulation of cell projection organization GO:0031344 206 0.045
nephron development GO:0072006 109 0.045
t helper 1 type immune response GO:0042088 25 0.045
Mouse
leukocyte migration GO:0050900 124 0.045
negative regulation of immune effector process GO:0002698 55 0.045
Mouse
nucleotide metabolic process GO:0009117 332 0.045
negative regulation of kinase activity GO:0033673 81 0.045
mesonephros development GO:0001823 97 0.045
synapse organization GO:0050808 125 0.044
cytoplasmic transport GO:0016482 234 0.044
tissue homeostasis GO:0001894 115 0.043
lymphocyte activation involved in immune response GO:0002285 93 0.043
Mouse
regulation of type 2 immune response GO:0002828 18 0.043
Mouse
stem cell differentiation GO:0048863 268 0.043
positive regulation of t cell activation GO:0050870 101 0.042
Mouse
multicellular organismal homeostasis GO:0048871 164 0.042
circulatory system process GO:0003013 197 0.042
regulation of apoptotic signaling pathway GO:2001233 197 0.042
digestive system development GO:0055123 200 0.042
extrinsic apoptotic signaling pathway GO:0097191 126 0.042
cation transport GO:0006812 399 0.042
hexose metabolic process GO:0019318 98 0.041
regulation of protein transport GO:0051223 163 0.041
Mouse
chemotaxis GO:0006935 247 0.041
carbohydrate derivative biosynthetic process GO:1901137 183 0.041
response to molecule of bacterial origin GO:0002237 143 0.040
carbohydrate metabolic process GO:0005975 230 0.040
b cell activation GO:0042113 161 0.040
small gtpase mediated signal transduction GO:0007264 97 0.040
t cell activation involved in immune response GO:0002286 43 0.040
Mouse
cellular response to insulin stimulus GO:0032869 78 0.039
Mouse
regulation of cellular response to insulin stimulus GO:1900076 30 0.039
Mouse
glycosyl compound metabolic process GO:1901657 246 0.039
sensory organ morphogenesis GO:0090596 242 0.039
regulation of cellular response to stress GO:0080135 159 0.039
positive regulation of alpha beta t cell activation GO:0046635 39 0.039
Mouse
organophosphate biosynthetic process GO:0090407 122 0.038
purine ribonucleoside metabolic process GO:0046128 241 0.038
nucleoside triphosphate metabolic process GO:0009141 230 0.038
stem cell development GO:0048864 219 0.038
glycoprotein biosynthetic process GO:0009101 89 0.037
cellular macromolecule catabolic process GO:0044265 206 0.037
response to monosaccharide GO:0034284 67 0.037
ribose phosphate metabolic process GO:0019693 291 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.037
developmental maturation GO:0021700 193 0.037
mesonephric tubule development GO:0072164 94 0.037
steroid metabolic process GO:0008202 119 0.036
protein maturation GO:0051604 176 0.036
primary neural tube formation GO:0014020 95 0.036
reactive oxygen species metabolic process GO:0072593 84 0.036
neural tube closure GO:0001843 90 0.036
transmembrane transport GO:0055085 412 0.036
retina development in camera type eye GO:0060041 119 0.036
glucose metabolic process GO:0006006 92 0.036
ribonucleoside metabolic process GO:0009119 245 0.036
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.035
negative regulation of response to wounding GO:1903035 77 0.035
Mouse
positive regulation of immune effector process GO:0002699 107 0.035
Mouse
bmp signaling pathway GO:0030509 93 0.035
nucleoside phosphate metabolic process GO:0006753 338 0.035
regulation of leukocyte mediated immunity GO:0002703 104 0.035
organic hydroxy compound metabolic process GO:1901615 203 0.035
purine nucleotide metabolic process GO:0006163 302 0.035
cellular carbohydrate metabolic process GO:0044262 119 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
spermatogenesis GO:0007283 284 0.034
negative regulation of cd4 positive alpha beta t cell activation GO:2000515 10 0.034
Mouse
striated muscle tissue development GO:0014706 293 0.034
positive regulation of neuron apoptotic process GO:0043525 25 0.034
rho protein signal transduction GO:0007266 32 0.034
wound healing GO:0042060 157 0.034
regulation of nucleoside metabolic process GO:0009118 130 0.034
regulation of body fluid levels GO:0050878 162 0.034
regulation of proteolysis GO:0030162 164 0.033
response to insulin GO:0032868 100 0.033
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.033
cellular ion homeostasis GO:0006873 165 0.033
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.033
tube formation GO:0035148 140 0.033
embryonic organ morphogenesis GO:0048562 276 0.033
tissue remodeling GO:0048771 102 0.033
axonogenesis GO:0007409 274 0.033
cytokine secretion GO:0050663 72 0.033
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.033
skeletal muscle organ development GO:0060538 163 0.033
sequestering of calcium ion GO:0051208 18 0.033
positive regulation of cd4 positive alpha beta t cell differentiation GO:0043372 14 0.033
Mouse
type 2 immune response GO:0042092 23 0.033
Mouse
organophosphate catabolic process GO:0046434 232 0.032
purine ribonucleoside catabolic process GO:0046130 205 0.032
nucleotide catabolic process GO:0009166 217 0.032
regulation of erk1 and erk2 cascade GO:0070372 71 0.032
small molecule biosynthetic process GO:0044283 132 0.032
apoptotic signaling pathway GO:0097190 306 0.032
positive regulation of lymphocyte differentiation GO:0045621 61 0.032
Mouse
cell activation involved in immune response GO:0002263 126 0.032
Mouse
regulation of t cell differentiation GO:0045580 83 0.031
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.031
regulation of cell cycle GO:0051726 281 0.031
regulation of lipid biosynthetic process GO:0046890 54 0.031
t helper 2 cell differentiation GO:0045064 12 0.031
Mouse
muscle contraction GO:0006936 101 0.031
positive regulation of cell cycle GO:0045787 92 0.031
regulation of systemic arterial blood pressure GO:0003073 61 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
monocarboxylic acid metabolic process GO:0032787 191 0.031
regulation of organelle organization GO:0033043 289 0.031
generation of precursor metabolites and energy GO:0006091 103 0.031
neuron migration GO:0001764 122 0.030
nucleoside metabolic process GO:0009116 246 0.030
ribonucleoside triphosphate metabolic process GO:0009199 220 0.030
nitrogen compound transport GO:0071705 271 0.030
memory GO:0007613 58 0.030
purine nucleoside triphosphate catabolic process GO:0009146 203 0.029
response to radiation GO:0009314 165 0.029
positive regulation of adaptive immune response GO:0002821 61 0.029
Mouse
tyrosine phosphorylation of stat3 protein GO:0042503 12 0.029
Mouse
leukocyte mediated immunity GO:0002443 174 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
regulation of neuron death GO:1901214 134 0.029
digestive tract development GO:0048565 190 0.029
purine nucleotide catabolic process GO:0006195 211 0.029
regulation of nucleotide metabolic process GO:0006140 169 0.029
branching morphogenesis of an epithelial tube GO:0048754 159 0.028
glycoprotein metabolic process GO:0009100 116 0.028
skeletal system morphogenesis GO:0048705 203 0.028
sequestering of metal ion GO:0051238 19 0.028
regulation of glucose metabolic process GO:0010906 60 0.028
regulation of muscle system process GO:0090257 80 0.028
cell growth GO:0016049 130 0.028
positive regulation of growth GO:0045927 104 0.028
regulation of carbohydrate metabolic process GO:0006109 75 0.028
regulation of t helper 1 type immune response GO:0002825 17 0.028
Mouse
regulation of cellular catabolic process GO:0031329 242 0.028
positive regulation of cell motility GO:2000147 116 0.028
canonical wnt signaling pathway GO:0060070 130 0.027
regulation of establishment of protein localization GO:0070201 181 0.027
Mouse
purine nucleoside metabolic process GO:0042278 241 0.027
single organism cell adhesion GO:0098602 156 0.027
second messenger mediated signaling GO:0019932 73 0.027
regulation of ossification GO:0030278 112 0.027
lung development GO:0030324 164 0.027
negative regulation of neuron apoptotic process GO:0043524 92 0.027
aromatic compound catabolic process GO:0019439 286 0.027
layer formation in cerebral cortex GO:0021819 13 0.027
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.027
regulation of bmp signaling pathway GO:0030510 60 0.027
heart process GO:0003015 94 0.027
cognition GO:0050890 149 0.027
cellular response to hormone stimulus GO:0032870 150 0.027
Human Mouse
response to extracellular stimulus GO:0009991 127 0.027
extracellular matrix organization GO:0030198 147 0.027
carbohydrate transport GO:0008643 62 0.027
erbb signaling pathway GO:0038127 32 0.026
Mouse
regulation of nucleotide catabolic process GO:0030811 122 0.026
posttranscriptional regulation of gene expression GO:0010608 155 0.026
response to organic cyclic compound GO:0014070 198 0.026
Human
response to oxygen levels GO:0070482 62 0.026
activation of immune response GO:0002253 138 0.026
regulation of cellular response to growth factor stimulus GO:0090287 82 0.026
actin filament organization GO:0007015 113 0.026
mesonephric epithelium development GO:0072163 94 0.025
negative regulation of lymphocyte activation GO:0051250 91 0.025
Mouse
regulation of t helper cell differentiation GO:0045622 14 0.025
Mouse
nephron epithelium development GO:0072009 92 0.025
muscle system process GO:0003012 141 0.025
epithelial cell development GO:0002064 159 0.025
negative regulation of apoptotic signaling pathway GO:2001234 104 0.025
immune response activating signal transduction GO:0002757 116 0.025
purine containing compound catabolic process GO:0072523 213 0.025
membrane organization GO:0061024 245 0.025
circadian regulation of gene expression GO:0032922 48 0.025
regulation of cellular component size GO:0032535 121 0.024
regulation of epithelial cell proliferation GO:0050678 141 0.024
maintenance of location GO:0051235 89 0.024
regulation of t helper 2 cell differentiation GO:0045628 8 0.024
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.024
hepaticobiliary system development GO:0061008 67 0.024
regulation of system process GO:0044057 200 0.024
positive regulation of phospholipase activity GO:0010518 3 0.024
glycerolipid metabolic process GO:0046486 122 0.024
cellular metal ion homeostasis GO:0006875 151 0.024
hexose transport GO:0008645 56 0.024
chondrocyte differentiation GO:0002062 72 0.024
positive regulation of cd4 positive alpha beta t cell activation GO:2000516 16 0.024
Mouse
positive regulation of nucleoside metabolic process GO:0045979 91 0.024
ribonucleoside catabolic process GO:0042454 206 0.023
ribonucleotide catabolic process GO:0009261 208 0.023
regulation of protein maturation GO:1903317 96 0.023
regulation of ras gtpase activity GO:0032318 88 0.023
monosaccharide transport GO:0015749 58 0.023
blood circulation GO:0008015 195 0.023
phospholipid metabolic process GO:0006644 87 0.023
ras protein signal transduction GO:0007265 77 0.023
positive regulation of organelle organization GO:0010638 128 0.023
cation homeostasis GO:0055080 212 0.023
positive regulation of cytokine production GO:0001819 174 0.023
metal ion homeostasis GO:0055065 189 0.023
response to oxidative stress GO:0006979 123 0.023
glomerulus development GO:0032835 40 0.022
neural tube formation GO:0001841 108 0.022
regulation of map kinase activity GO:0043405 120 0.022
single fertilization GO:0007338 82 0.022
carbohydrate biosynthetic process GO:0016051 74 0.022
innate immune response GO:0045087 157 0.022
cellular response to oxidative stress GO:0034599 76 0.022
mesoderm development GO:0007498 100 0.022
ion transmembrane transport GO:0034220 361 0.022
regulation of purine nucleotide metabolic process GO:1900542 169 0.022
learning or memory GO:0007611 148 0.022
synaptic transmission GO:0007268 329 0.022
ureteric bud development GO:0001657 94 0.022
erythrocyte differentiation GO:0030218 88 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
regulation of gtp catabolic process GO:0033124 113 0.022
negative regulation of organelle organization GO:0010639 90 0.022
response to uv GO:0009411 44 0.022
response to epidermal growth factor GO:0070849 4 0.022
glycerolipid biosynthetic process GO:0045017 50 0.022
myotube differentiation GO:0014902 105 0.022
t cell differentiation involved in immune response GO:0002292 30 0.021
Mouse
divalent inorganic cation transport GO:0072511 178 0.021
positive regulation of cell adhesion GO:0045785 80 0.021
mitotic cell cycle GO:0000278 195 0.021
negative regulation of hydrolase activity GO:0051346 71 0.021
negative regulation of alpha beta t cell differentiation GO:0046639 12 0.021
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 95 0.021
negative regulation of neuron death GO:1901215 98 0.021
positive regulation of smooth muscle cell migration GO:0014911 4 0.021
negative regulation of mapk cascade GO:0043409 65 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
establishment of organelle localization GO:0051656 122 0.021
fatty acid metabolic process GO:0006631 121 0.021
intracellular receptor signaling pathway GO:0030522 74 0.021
glucose transport GO:0015758 56 0.021
cardiac chamber development GO:0003205 108 0.021
response to nutrient levels GO:0031667 109 0.021
positive regulation of lipid metabolic process GO:0045834 40 0.021
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 21 0.021
Mouse
spermatid differentiation GO:0048515 115 0.021
striated muscle cell development GO:0055002 125 0.021
hematopoietic progenitor cell differentiation GO:0002244 143 0.021
dephosphorylation GO:0016311 129 0.021
kidney morphogenesis GO:0060993 83 0.020
insulin receptor signaling pathway GO:0008286 49 0.020
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.020
tube closure GO:0060606 91 0.020
muscle cell development GO:0055001 133 0.020
bone mineralization GO:0030282 54 0.020
lymphocyte homeostasis GO:0002260 64 0.020
organic hydroxy compound biosynthetic process GO:1901617 77 0.020
myeloid cell homeostasis GO:0002262 114 0.020
defense response to bacterium GO:0042742 119 0.020
neurotransmitter secretion GO:0007269 62 0.020
hormone metabolic process GO:0042445 86 0.020
positive regulation of t cell proliferation GO:0042102 52 0.020
lymphocyte proliferation GO:0046651 164 0.020
regulation of purine nucleotide catabolic process GO:0033121 122 0.020
photoreceptor cell differentiation GO:0046530 52 0.020
cellular response to dna damage stimulus GO:0006974 207 0.020
peptide secretion GO:0002790 114 0.020
vesicle localization GO:0051648 86 0.019
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.019
positive regulation of leukocyte proliferation GO:0070665 73 0.019

Socs2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.064
nervous system disease DOID:863 0 0.064
cancer DOID:162 0 0.042
disease of cellular proliferation DOID:14566 0 0.042
organ system cancer DOID:0050686 0 0.042
disease by infectious agent DOID:0050117 0 0.025