Mus musculus

190 known processes

Sorl1

sortilin-related receptor, LDLR class A repeats-containing

(Aliases: mSorLA,2900010L19Rik,LR11,SorLA,AW261561,gp250,AI596264)

Sorl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heterocycle catabolic process GO:0046700 280 0.247
purine nucleoside catabolic process GO:0006152 205 0.237
amine metabolic process GO:0009308 45 0.229
ras protein signal transduction GO:0007265 77 0.221
regulation of cellular amino acid metabolic process GO:0006521 5 0.220
purine nucleotide catabolic process GO:0006195 211 0.207
purine containing compound catabolic process GO:0072523 213 0.202
nucleotide catabolic process GO:0009166 217 0.201
purine nucleotide metabolic process GO:0006163 302 0.196
nucleoside phosphate catabolic process GO:1901292 222 0.195
organophosphate catabolic process GO:0046434 232 0.188
regulation of cellular amine metabolic process GO:0033238 20 0.179
nucleoside phosphate metabolic process GO:0006753 338 0.175
organonitrogen compound catabolic process GO:1901565 264 0.174
glycosyl compound catabolic process GO:1901658 206 0.172
glycosyl compound metabolic process GO:1901657 246 0.171
nucleotide metabolic process GO:0009117 332 0.167
ribonucleotide catabolic process GO:0009261 208 0.165
cellular ketone metabolic process GO:0042180 84 0.162
nucleoside triphosphate metabolic process GO:0009141 230 0.161
purine ribonucleoside catabolic process GO:0046130 205 0.158
guanosine containing compound metabolic process GO:1901068 144 0.157
ion transmembrane transport GO:0034220 361 0.154
cellular amino acid metabolic process GO:0006520 103 0.152
nucleoside catabolic process GO:0009164 206 0.146
ribonucleoside catabolic process GO:0042454 206 0.145
ribonucleoside triphosphate metabolic process GO:0009199 220 0.145
ribonucleoside metabolic process GO:0009119 245 0.144
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.143
nucleobase containing small molecule metabolic process GO:0055086 352 0.143
ribonucleoside triphosphate catabolic process GO:0009203 199 0.142
inorganic cation transmembrane transport GO:0098662 207 0.141
purine nucleoside triphosphate catabolic process GO:0009146 203 0.139
peptidyl amino acid modification GO:0018193 336 0.138
nucleoside triphosphate catabolic process GO:0009143 205 0.137
purine containing compound metabolic process GO:0072521 311 0.134
purine ribonucleotide metabolic process GO:0009150 290 0.134
cellular amine metabolic process GO:0044106 44 0.130
regulation of cellular ketone metabolic process GO:0010565 66 0.130
nucleoside metabolic process GO:0009116 246 0.129
regulation of nucleoside metabolic process GO:0009118 130 0.129
purine nucleoside triphosphate metabolic process GO:0009144 226 0.127
ribonucleotide metabolic process GO:0009259 291 0.121
regulation of hydrolase activity GO:0051336 246 0.121
rho protein signal transduction GO:0007266 32 0.121
regulation of nucleotide metabolic process GO:0006140 169 0.119
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.119
organic cyclic compound catabolic process GO:1901361 295 0.110
positive regulation of cellular amine metabolic process GO:0033240 5 0.110
synaptic transmission GO:0007268 329 0.110
carbohydrate derivative catabolic process GO:1901136 231 0.109
cation transport GO:0006812 399 0.109
purine ribonucleoside metabolic process GO:0046128 241 0.106
protein catabolic process GO:0030163 221 0.105
Human
regulation of ion transport GO:0043269 215 0.105
inorganic ion transmembrane transport GO:0098660 234 0.104
purine ribonucleotide catabolic process GO:0009154 208 0.104
cellular nitrogen compound catabolic process GO:0044270 280 0.104
regulation of ras gtpase activity GO:0032318 88 0.102
peptidyl serine modification GO:0018209 83 0.101
transmembrane transport GO:0055085 412 0.101
positive regulation of protein modification process GO:0031401 299 0.099
negative regulation of molecular function GO:0044092 258 0.097
regulation of purine nucleotide metabolic process GO:1900542 169 0.096
positive regulation of protein phosphorylation GO:0001934 242 0.094
positive regulation of hydrolase activity GO:0051345 148 0.094
regulation of cellular catabolic process GO:0031329 242 0.094
muscle cell differentiation GO:0042692 261 0.092
Mouse
ribose phosphate metabolic process GO:0019693 291 0.092
carbohydrate metabolic process GO:0005975 230 0.092
purine nucleoside metabolic process GO:0042278 241 0.092
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.091
immune effector process GO:0002252 321 0.089
small gtpase mediated signal transduction GO:0007264 97 0.088
aromatic compound catabolic process GO:0019439 286 0.086
leukocyte differentiation GO:0002521 342 0.083
positive regulation of cellular catabolic process GO:0031331 148 0.083
gtp metabolic process GO:0046039 144 0.081
multicellular organismal signaling GO:0035637 91 0.081
positive regulation of nucleotide catabolic process GO:0030813 88 0.081
negative regulation of protein phosphorylation GO:0001933 126 0.080
positive regulation of nucleotide metabolic process GO:0045981 114 0.078
negative regulation of cellular component organization GO:0051129 194 0.078
regulation of purine nucleotide catabolic process GO:0033121 122 0.077
cell adhesion GO:0007155 329 0.076
positive regulation of ras gtpase activity GO:0032320 65 0.076
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.076
regulation of neuron differentiation GO:0045664 281 0.076
actin cytoskeleton organization GO:0030036 220 0.074
regulation of protein kinase activity GO:0045859 232 0.072
regulation of anatomical structure size GO:0090066 178 0.072
guanosine containing compound catabolic process GO:1901069 144 0.072
sequestering of metal ion GO:0051238 19 0.072
regulation of kinase activity GO:0043549 249 0.071
regulation of cellular component size GO:0032535 121 0.070
regulation of cell projection organization GO:0031344 206 0.070
regulation of nucleotide catabolic process GO:0030811 122 0.069
regulation of mapk cascade GO:0043408 248 0.069
cation transmembrane transport GO:0098655 266 0.068
gtp catabolic process GO:0006184 143 0.068
divalent metal ion transport GO:0070838 172 0.067
macromolecule catabolic process GO:0009057 281 0.067
Human
regulation of gtp catabolic process GO:0033124 113 0.067
peptidyl serine phosphorylation GO:0018105 74 0.065
membrane organization GO:0061024 245 0.064
neuronal action potential GO:0019228 54 0.064
positive regulation of nucleoside metabolic process GO:0045979 91 0.064
regulation of transferase activity GO:0051338 263 0.062
positive regulation of programmed cell death GO:0043068 218 0.062
axonogenesis GO:0007409 274 0.062
apoptotic signaling pathway GO:0097190 306 0.061
cytoplasmic transport GO:0016482 234 0.061
Human Yeast
positive regulation of cell death GO:0010942 224 0.060
sensory organ morphogenesis GO:0090596 242 0.059
negative regulation of nervous system development GO:0051961 156 0.059
regulation of transmembrane transport GO:0034762 128 0.059
positive regulation of nervous system development GO:0051962 221 0.058
regulation of neuron projection development GO:0010975 169 0.058
regulation of organelle organization GO:0033043 289 0.057
positive regulation of gtpase activity GO:0043547 85 0.056
regulation of rho gtpase activity GO:0032319 58 0.056
divalent inorganic cation homeostasis GO:0072507 138 0.056
calcium ion homeostasis GO:0055074 127 0.055
positive regulation of gtp catabolic process GO:0033126 85 0.055
regulation of membrane potential GO:0042391 192 0.055
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.054
camera type eye development GO:0043010 266 0.054
cellular homeostasis GO:0019725 240 0.054
positive regulation of kinase activity GO:0033674 155 0.054
cation homeostasis GO:0055080 212 0.052
negative regulation of cellular protein metabolic process GO:0032269 247 0.052
regulation of ras protein signal transduction GO:0046578 114 0.052
protein modification by small protein conjugation or removal GO:0070647 207 0.052
regulation of peptidase activity GO:0052547 96 0.052
positive regulation of apoptotic process GO:0043065 217 0.052
gland development GO:0048732 330 0.051
cellular calcium ion homeostasis GO:0006874 119 0.050
intracellular protein transport GO:0006886 204 0.050
Human Yeast
regulation of vesicle mediated transport GO:0060627 139 0.049
Human
striated muscle tissue development GO:0014706 293 0.049
response to growth factor GO:0070848 198 0.049
multicellular organism growth GO:0035264 161 0.048
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.048
peptidyl tyrosine phosphorylation GO:0018108 143 0.048
protein maturation GO:0051604 176 0.047
maintenance of location GO:0051235 89 0.047
calcium ion transport GO:0006816 159 0.047
cellular macromolecule catabolic process GO:0044265 206 0.047
regulation of proteolysis GO:0030162 164 0.047
positive regulation of mapk cascade GO:0043410 170 0.046
regulation of cell adhesion GO:0030155 154 0.046
regulation of ion transmembrane transport GO:0034765 119 0.046
positive regulation of protein kinase activity GO:0045860 144 0.046
protein ubiquitination GO:0016567 171 0.046
locomotory behavior GO:0007626 195 0.045
transmission of nerve impulse GO:0019226 76 0.045
negative regulation of protein metabolic process GO:0051248 282 0.045
regulation of metal ion transport GO:0010959 106 0.045
lymphocyte differentiation GO:0030098 242 0.045
negative regulation of cellular amine metabolic process GO:0033239 1 0.045
muscle system process GO:0003012 141 0.044
cellular divalent inorganic cation homeostasis GO:0072503 127 0.044
developmental maturation GO:0021700 193 0.044
microtubule based process GO:0007017 236 0.044
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.043
endomembrane system organization GO:0010256 147 0.043
muscle tissue development GO:0060537 308 0.043
regulation of cellular response to stress GO:0080135 159 0.043
sequestering of calcium ion GO:0051208 18 0.043
regulation of apoptotic signaling pathway GO:2001233 197 0.043
protein processing GO:0016485 163 0.043
negative regulation of neuron projection development GO:0010977 50 0.042
dephosphorylation GO:0016311 129 0.042
cellular response to growth factor stimulus GO:0071363 197 0.042
lymphocyte mediated immunity GO:0002449 139 0.042
muscle cell development GO:0055001 133 0.041
cellular protein catabolic process GO:0044257 155 0.040
plasma membrane organization GO:0007009 90 0.040
endocytosis GO:0006897 168 0.040
cellular protein complex assembly GO:0043623 116 0.040
regulation of hormone levels GO:0010817 211 0.040
regulation of ion homeostasis GO:2000021 64 0.040
protein modification by small protein conjugation GO:0032446 187 0.040
negative regulation of protein modification process GO:0031400 163 0.040
rap protein signal transduction GO:0032486 3 0.039
anion transport GO:0006820 177 0.039
negative regulation of synapse assembly GO:0051964 3 0.039
learning or memory GO:0007611 148 0.039
cellular metal ion homeostasis GO:0006875 151 0.039
peptidyl tyrosine modification GO:0018212 145 0.038
positive regulation of cell development GO:0010720 237 0.038
regulation of map kinase activity GO:0043405 120 0.038
activation of immune response GO:0002253 138 0.038
epidermis development GO:0008544 187 0.038
g protein coupled receptor signaling pathway GO:0007186 243 0.038
cellular response to organonitrogen compound GO:0071417 145 0.038
mapk cascade GO:0000165 281 0.038
cellular ion homeostasis GO:0006873 165 0.038
intrinsic apoptotic signaling pathway GO:0097193 132 0.037
skeletal system development GO:0001501 356 0.037
oxidation reduction process GO:0055114 342 0.037
cellular carbohydrate metabolic process GO:0044262 119 0.037
metal ion homeostasis GO:0055065 189 0.037
regulation of protein serine threonine kinase activity GO:0071900 157 0.037
organelle localization GO:0051640 179 0.037
regulation of secretion by cell GO:1903530 249 0.037
cellular chemical homeostasis GO:0055082 215 0.037
positive regulation of rho gtpase activity GO:0032321 41 0.036
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.036
regulation of secretion GO:0051046 274 0.036
ubiquitin dependent protein catabolic process GO:0006511 129 0.036
positive regulation of growth GO:0045927 104 0.036
regulation of system process GO:0044057 200 0.036
regulation of cell motility GO:2000145 236 0.036
Human
regulation of cell migration GO:0030334 219 0.035
Human
calcium ion transmembrane transport GO:0070588 85 0.035
divalent inorganic cation transport GO:0072511 178 0.035
spermatogenesis GO:0007283 284 0.035
negative regulation of phosphate metabolic process GO:0045936 184 0.035
skin development GO:0043588 220 0.035
protein polymerization GO:0051258 57 0.035
telencephalon development GO:0021537 186 0.035
negative regulation of cell proliferation GO:0008285 296 0.035
organic hydroxy compound metabolic process GO:1901615 203 0.034
histone modification GO:0016570 159 0.034
negative regulation of transferase activity GO:0051348 85 0.034
action potential GO:0001508 78 0.034
actin filament polymerization GO:0030041 44 0.034
forebrain development GO:0030900 302 0.034
cellular lipid metabolic process GO:0044255 323 0.033
nitrogen compound transport GO:0071705 271 0.033
alcohol metabolic process GO:0006066 116 0.033
positive regulation of lymphocyte activation GO:0051251 140 0.033
positive regulation of neuron differentiation GO:0045666 141 0.033
regulation of protein catabolic process GO:0042176 108 0.033
Human
response to organonitrogen compound GO:0010243 246 0.033
Mouse
organelle fission GO:0048285 170 0.033
angiogenesis GO:0001525 201 0.032
proteasomal protein catabolic process GO:0010498 98 0.032
b cell activation GO:0042113 161 0.032
cell type specific apoptotic process GO:0097285 268 0.032
regulation of intracellular transport GO:0032386 159 0.032
Human
ossification GO:0001503 216 0.032
negative regulation of phosphorylation GO:0042326 166 0.032
cognition GO:0050890 149 0.031
negative regulation of cell development GO:0010721 169 0.031
cell activation involved in immune response GO:0002263 126 0.031
single organismal cell cell adhesion GO:0016337 131 0.031
atp metabolic process GO:0046034 75 0.031
regulation of rho protein signal transduction GO:0035023 71 0.031
retina development in camera type eye GO:0060041 119 0.030
cell growth GO:0016049 130 0.030
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.030
hemostasis GO:0007599 78 0.030
regulation of asymmetric cell division GO:0009786 4 0.030
inflammatory response GO:0006954 244 0.029
developmental cell growth GO:0048588 84 0.029
response to peptide GO:1901652 136 0.029
Mouse
muscle contraction GO:0006936 101 0.029
regulation of cell size GO:0008361 72 0.029
sensory perception GO:0007600 245 0.029
positive regulation of protein catabolic process GO:0045732 60 0.029
Human
regulation of cell activation GO:0050865 289 0.029
response to organic cyclic compound GO:0014070 198 0.029
male gamete generation GO:0048232 285 0.029
protein localization to plasma membrane GO:0072659 57 0.029
stress activated protein kinase signaling cascade GO:0031098 81 0.029
blood coagulation GO:0007596 76 0.029
response to transforming growth factor beta GO:0071559 88 0.029
adult locomotory behavior GO:0008344 91 0.029
nerve development GO:0021675 67 0.028
regulation of protein processing GO:0070613 96 0.028
homeostasis of number of cells GO:0048872 210 0.028
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.028
regulation of lymphocyte activation GO:0051249 240 0.028
positive regulation of neuron projection development GO:0010976 79 0.028
phosphatidylinositol metabolic process GO:0046488 45 0.028
nucleoside monophosphate metabolic process GO:0009123 85 0.028
germ cell development GO:0007281 185 0.028
regulation of neuron death GO:1901214 134 0.028
positive regulation of cell activation GO:0050867 158 0.028
ear development GO:0043583 200 0.028
single organism cell adhesion GO:0098602 156 0.028
chemotaxis GO:0006935 247 0.027
olfactory learning GO:0008355 2 0.027
microtubule based movement GO:0007018 84 0.027
regulation of cell substrate adhesion GO:0010810 73 0.027
positive regulation of transferase activity GO:0051347 167 0.027
t cell differentiation GO:0030217 174 0.027
neural tube formation GO:0001841 108 0.027
membrane tubulation GO:0097320 4 0.027
lipid localization GO:0010876 126 0.027
regulation of extent of cell growth GO:0061387 52 0.027
neuron death GO:0070997 154 0.027
response to radiation GO:0009314 165 0.027
positive regulation of cell projection organization GO:0031346 95 0.027
synapse organization GO:0050808 125 0.027
release of sequestered calcium ion into cytosol GO:0051209 42 0.027
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.027
positive regulation of proteolysis GO:0045862 85 0.026
negative regulation of immune system process GO:0002683 209 0.026
positive regulation of apoptotic signaling pathway GO:2001235 95 0.026
morphogenesis of a branching epithelium GO:0061138 193 0.026
defecation GO:0030421 1 0.026
cellular response to cytokine stimulus GO:0071345 189 0.026
negative regulation of cell projection organization GO:0031345 56 0.026
regulation of neurotransmitter levels GO:0001505 87 0.026
atp catabolic process GO:0006200 55 0.026
organic anion transport GO:0015711 137 0.026
regulation of protein localization GO:0032880 231 0.026
Human
regulation of response to wounding GO:1903034 189 0.025
hexose metabolic process GO:0019318 98 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
regulation of body fluid levels GO:0050878 162 0.025
regulation of endopeptidase activity GO:0052548 89 0.025
t cell activation GO:0042110 289 0.025
regulation of cytoskeleton organization GO:0051493 122 0.025
vesicle localization GO:0051648 86 0.025
response to molecule of bacterial origin GO:0002237 143 0.025
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.025
protein localization to organelle GO:0033365 185 0.025
limbic system development GO:0021761 72 0.025
embryonic organ morphogenesis GO:0048562 276 0.025
modification dependent macromolecule catabolic process GO:0043632 133 0.025
modification dependent protein catabolic process GO:0019941 133 0.025
ribonucleoside monophosphate metabolic process GO:0009161 80 0.024
jnk cascade GO:0007254 72 0.024
positive regulation of secretion GO:0051047 130 0.024
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.024
positive regulation of ion transport GO:0043270 65 0.024
positive regulation of phagocytosis engulfment GO:0060100 3 0.024
glial cell differentiation GO:0010001 131 0.024
myelination GO:0042552 74 0.024
positive regulation of organelle organization GO:0010638 128 0.024
regulation of cellular component biogenesis GO:0044087 181 0.024
cellular response to biotic stimulus GO:0071216 92 0.023
regulation of jnk cascade GO:0046328 62 0.023
wound healing GO:0042060 157 0.023
gliogenesis GO:0042063 141 0.023
leukocyte activation involved in immune response GO:0002366 126 0.023
response to oxidative stress GO:0006979 123 0.023
cell substrate adhesion GO:0031589 130 0.023
axon ensheathment GO:0008366 76 0.023
stress activated mapk cascade GO:0051403 80 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
blood vessel morphogenesis GO:0048514 285 0.023
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.023
regulation of cell cycle GO:0051726 281 0.022
cellular response to ethanol GO:0071361 3 0.022
glial cell development GO:0021782 54 0.022
phospholipid metabolic process GO:0006644 87 0.022
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.022
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.022
establishment of organelle localization GO:0051656 122 0.022
lymphocyte activation involved in immune response GO:0002285 93 0.022
regulation of actin filament based process GO:0032970 99 0.022
regulation of homeostatic process GO:0032844 182 0.022
cardiac muscle contraction GO:0060048 32 0.022
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.022
carbohydrate homeostasis GO:0033500 128 0.022
positive regulation of cell adhesion GO:0045785 80 0.022
nuclear division GO:0000280 158 0.022
response to inorganic substance GO:0010035 96 0.022
blood circulation GO:0008015 195 0.022
heart contraction GO:0060047 93 0.021
negative regulation of kinase activity GO:0033673 81 0.021
ensheathment of neurons GO:0007272 76 0.021
response to insulin GO:0032868 100 0.021
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.021
immune response activating signal transduction GO:0002757 116 0.021
negative regulation of growth GO:0045926 99 0.021
cellular response to lipid GO:0071396 145 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.021
ribonucleoside monophosphate catabolic process GO:0009158 57 0.021
negative regulation of protein processing GO:0010955 79 0.021
glucose metabolic process GO:0006006 92 0.021
alpha beta t cell activation GO:0046631 91 0.021
regulation of muscle system process GO:0090257 80 0.021
purine nucleoside monophosphate catabolic process GO:0009128 58 0.021
ventral trunk neural crest cell migration GO:0036486 4 0.021
midgut development GO:0007494 4 0.021
striated muscle cell development GO:0055002 125 0.021
adult behavior GO:0030534 135 0.021
actin polymerization or depolymerization GO:0008154 54 0.021
protein targeting GO:0006605 143 0.021
Human Yeast
response to lipopolysaccharide GO:0032496 128 0.021
negative regulation of hydrolase activity GO:0051346 71 0.021
reactive oxygen species biosynthetic process GO:1903409 8 0.021
microtubule cytoskeleton organization GO:0000226 157 0.021
organelle assembly GO:0070925 177 0.021
cytokine production GO:0001816 319 0.020
reactive nitrogen species metabolic process GO:2001057 0 0.020
response to peptide hormone GO:0043434 127 0.020
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
calcium ion transport into cytosol GO:0060402 48 0.020
neuron apoptotic process GO:0051402 142 0.020
dna metabolic process GO:0006259 303 0.020
compound eye development GO:0048749 1 0.020
morphogenesis of a branching structure GO:0001763 203 0.020
monocarboxylic acid metabolic process GO:0032787 191 0.020
regulation of synaptic plasticity GO:0048167 87 0.020
regulation of leukocyte differentiation GO:1902105 159 0.020
regulation of endocytosis GO:0030100 69 0.020
meiotic cell cycle GO:0051321 122 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.020
positive regulation of endocytosis GO:0045807 42 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.020
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.020
positive regulation of secretion by cell GO:1903532 114 0.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.020
regulation of reactive oxygen species metabolic process GO:2000377 40 0.020
morphogenesis of embryonic epithelium GO:0016331 159 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.020
fat cell differentiation GO:0045444 160 0.020
striated muscle contraction GO:0006941 45 0.020
myeloid cell differentiation GO:0030099 233 0.020
protein import into nucleus GO:0006606 95 0.020
epithelial tube morphogenesis GO:0060562 303 0.020
regulation of blood circulation GO:1903522 93 0.019
photoreceptor cell differentiation GO:0046530 52 0.019
neuron migration GO:0001764 122 0.019
developmental growth involved in morphogenesis GO:0060560 138 0.019
cerebral cortex development GO:0021987 86 0.019
regulation of hormone secretion GO:0046883 88 0.019
establishment of protein localization to membrane GO:0090150 54 0.019
purine nucleoside monophosphate metabolic process GO:0009126 81 0.019
central nervous system neuron differentiation GO:0021953 162 0.019
positive regulation of cytokine production GO:0001819 174 0.019
regulation of t cell activation GO:0050863 170 0.019
response to light stimulus GO:0009416 135 0.019
regulation of angiogenesis GO:0045765 81 0.019
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.019
covalent chromatin modification GO:0016569 163 0.019
regulation of vasculature development GO:1901342 88 0.019
protein autophosphorylation GO:0046777 61 0.019
glycerophospholipid metabolic process GO:0006650 71 0.019
glycerolipid metabolic process GO:0046486 122 0.019
neural tube closure GO:0001843 90 0.019
circulatory system process GO:0003013 197 0.019
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.019
amide transport GO:0042886 138 0.019
regulation of feeding behavior GO:0060259 3 0.019
protein localization to nucleus GO:0034504 121 0.018
peptidyl threonine phosphorylation GO:0018107 31 0.018
mitotic cell cycle process GO:1903047 159 0.018
cardiac muscle cell contraction GO:0086003 7 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
mitotic cell cycle GO:0000278 195 0.018
regulation of voltage gated calcium channel activity GO:1901385 4 0.018
lipid transport GO:0006869 98 0.018
neuron projection extension GO:1990138 64 0.018
regulation of stress activated mapk cascade GO:0032872 69 0.018
pallium development GO:0021543 120 0.018
positive regulation of rap gtpase activity GO:0032854 3 0.018
cell division GO:0051301 120 0.018
leukocyte migration GO:0050900 124 0.018
regulation of intracellular protein transport GO:0033157 82 0.018
Human
negative regulation of peptidase activity GO:0010466 46 0.018
regulation of ral gtpase activity GO:0032315 4 0.018
cytokinetic process GO:0032506 2 0.018
regionalization GO:0003002 337 0.018
wnt signaling pathway GO:0016055 188 0.018
lateral inhibition GO:0046331 1 0.018
negative regulation of protein maturation GO:1903318 79 0.018
bone development GO:0060348 120 0.018
immune response regulating signaling pathway GO:0002764 125 0.018
cell maturation GO:0048469 127 0.018
asymmetric stem cell division GO:0098722 3 0.018
cellular response to molecule of bacterial origin GO:0071219 83 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
regulation of lymphocyte proliferation GO:0050670 117 0.018
lipid modification GO:0030258 65 0.018
positive regulation of map kinase activity GO:0043406 84 0.018
regulation of cell cycle process GO:0010564 160 0.017
cytosolic calcium ion homeostasis GO:0051480 70 0.017
regulation of axon extension GO:0030516 43 0.017
cellular response to dna damage stimulus GO:0006974 207 0.017
chromatin organization GO:0006325 206 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
Human
coagulation GO:0050817 78 0.017
b cell differentiation GO:0030183 78 0.017
homotypic cell cell adhesion GO:0034109 28 0.017
spermatid differentiation GO:0048515 115 0.017
regulation of transcription from rna polymerase ii promoter by galactose GO:0000431 1 0.017
single organism nuclear import GO:1902593 95 0.017
regulation of clathrin mediated endocytosis GO:2000369 4 0.017
regulation of ion transmembrane transporter activity GO:0032412 54 0.017
regulation of high voltage gated calcium channel activity GO:1901841 2 0.017

Sorl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.070
Human
central nervous system disease DOID:331 0 0.070
Human
nervous system disease DOID:863 0 0.070
Human
bone disease DOID:0080001 0 0.021
connective tissue disease DOID:65 0 0.021
musculoskeletal system disease DOID:17 0 0.021
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.017