Mus musculus

39 known processes

Sort1

sortilin 1

(Aliases: AI852375,2900053A11Rik,Ntsr3,Ntr3)

Sort1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small gtpase mediated signal transduction GO:0007264 97 0.320
rho protein signal transduction GO:0007266 32 0.207
ras protein signal transduction GO:0007265 77 0.204
ion transmembrane transport GO:0034220 361 0.195
regulation of ras protein signal transduction GO:0046578 114 0.174
nucleotide catabolic process GO:0009166 217 0.162
cation transport GO:0006812 399 0.140
axonogenesis GO:0007409 274 0.137
transmembrane transport GO:0055085 412 0.131
nucleoside triphosphate metabolic process GO:0009141 230 0.118
multicellular organismal signaling GO:0035637 91 0.114
membrane organization GO:0061024 245 0.113
organonitrogen compound catabolic process GO:1901565 264 0.111
inorganic cation transmembrane transport GO:0098662 207 0.111
purine nucleoside catabolic process GO:0006152 205 0.108
cation transmembrane transport GO:0098655 266 0.107
regulation of membrane potential GO:0042391 192 0.106
nucleoside catabolic process GO:0009164 206 0.105
positive regulation of cell death GO:0010942 224 0.102
glycosyl compound catabolic process GO:1901658 206 0.102
ribonucleoside metabolic process GO:0009119 245 0.100
action potential GO:0001508 78 0.097
regulation of cell projection organization GO:0031344 206 0.092
mapk cascade GO:0000165 281 0.089
Mouse
synaptic transmission GO:0007268 329 0.089
purine nucleoside triphosphate catabolic process GO:0009146 203 0.089
purine ribonucleoside metabolic process GO:0046128 241 0.084
purine nucleoside triphosphate metabolic process GO:0009144 226 0.083
purine containing compound catabolic process GO:0072523 213 0.083
negative regulation of nervous system development GO:0051961 156 0.082
Mouse
ribose phosphate metabolic process GO:0019693 291 0.081
purine nucleotide metabolic process GO:0006163 302 0.078
nucleoside phosphate catabolic process GO:1901292 222 0.078
negative regulation of cell development GO:0010721 169 0.076
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.075
purine containing compound metabolic process GO:0072521 311 0.075
positive regulation of ras gtpase activity GO:0032320 65 0.074
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.074
cellular nitrogen compound catabolic process GO:0044270 280 0.073
purine ribonucleotide metabolic process GO:0009150 290 0.071
regulation of neuron differentiation GO:0045664 281 0.070
organophosphate catabolic process GO:0046434 232 0.069
purine ribonucleotide catabolic process GO:0009154 208 0.068
protein localization to membrane GO:0072657 108 0.067
regulation of cellular component size GO:0032535 121 0.067
nucleoside triphosphate catabolic process GO:0009143 205 0.065
neuron projection extension GO:1990138 64 0.064
glycosyl compound metabolic process GO:1901657 246 0.064
ribonucleoside triphosphate catabolic process GO:0009203 199 0.064
response to peptide hormone GO:0043434 127 0.063
regulation of rho protein signal transduction GO:0035023 71 0.063
regulation of neuron projection development GO:0010975 169 0.063
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.062
aromatic compound catabolic process GO:0019439 286 0.061
neuronal action potential GO:0019228 54 0.060
purine ribonucleoside catabolic process GO:0046130 205 0.059
intracellular protein transport GO:0006886 204 0.059
response to growth factor GO:0070848 198 0.059
Human
transmission of nerve impulse GO:0019226 76 0.057
calcium ion transport GO:0006816 159 0.057
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.057
glucose import GO:0046323 32 0.057
nucleobase containing small molecule metabolic process GO:0055086 352 0.056
ribonucleoside triphosphate metabolic process GO:0009199 220 0.055
regulation of gtp catabolic process GO:0033124 113 0.055
ribonucleotide catabolic process GO:0009261 208 0.055
nucleoside metabolic process GO:0009116 246 0.054
telencephalon development GO:0021537 186 0.054
regulation of ras gtpase activity GO:0032318 88 0.054
forebrain development GO:0030900 302 0.054
regulation of cell size GO:0008361 72 0.054
guanosine containing compound catabolic process GO:1901069 144 0.053
ribonucleoside catabolic process GO:0042454 206 0.052
inorganic ion transmembrane transport GO:0098660 234 0.052
positive regulation of gtp catabolic process GO:0033126 85 0.051
nucleoside phosphate metabolic process GO:0006753 338 0.051
nucleotide metabolic process GO:0009117 332 0.050
cellular amino acid metabolic process GO:0006520 103 0.050
regulation of nucleoside metabolic process GO:0009118 130 0.050
chemotaxis GO:0006935 247 0.049
divalent inorganic cation transport GO:0072511 178 0.049
divalent metal ion transport GO:0070838 172 0.049
purine nucleotide catabolic process GO:0006195 211 0.049
asymmetric neuroblast division GO:0055059 1 0.049
regulation of cellular amino acid metabolic process GO:0006521 5 0.048
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.048
cell type specific apoptotic process GO:0097285 268 0.047
asymmetric stem cell division GO:0098722 3 0.047
heterocycle catabolic process GO:0046700 280 0.046
calcium ion transmembrane transport GO:0070588 85 0.046
negative regulation of cell projection organization GO:0031345 56 0.046
skeletal system development GO:0001501 356 0.045
negative regulation of cellular component organization GO:0051129 194 0.045
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.045
organic cyclic compound catabolic process GO:1901361 295 0.045
cellular amine metabolic process GO:0044106 44 0.045
hexose transport GO:0008645 56 0.045
regulation of purine nucleotide catabolic process GO:0033121 122 0.044
neuron neuron synaptic transmission GO:0007270 69 0.044
positive regulation of gtpase activity GO:0043547 85 0.043
ribonucleotide metabolic process GO:0009259 291 0.043
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.043
regulation of extent of cell growth GO:0061387 52 0.043
cognition GO:0050890 149 0.043
carbohydrate homeostasis GO:0033500 128 0.042
regulation of mapk cascade GO:0043408 248 0.042
Mouse
gtp metabolic process GO:0046039 144 0.042
retrograde transport endosome to golgi GO:0042147 2 0.041
regulation of cell migration GO:0030334 219 0.041
cell fate commitment GO:0045165 210 0.040
sodium ion transmembrane transport GO:0035725 49 0.039
striated muscle tissue development GO:0014706 293 0.039
purine nucleoside metabolic process GO:0042278 241 0.039
response to insulin GO:0032868 100 0.038
positive regulation of nervous system development GO:0051962 221 0.038
cellular response to oxidative stress GO:0034599 76 0.038
regulation of glucose transport GO:0010827 32 0.037
reactive oxygen species metabolic process GO:0072593 84 0.037
monosaccharide transport GO:0015749 58 0.037
anion transport GO:0006820 177 0.037
positive regulation of nucleoside metabolic process GO:0045979 91 0.036
developmental growth involved in morphogenesis GO:0060560 138 0.036
regulation of cell motility GO:2000145 236 0.036
regulation of cytoskeleton organization GO:0051493 122 0.036
glucose transport GO:0015758 56 0.035
cellular response to insulin stimulus GO:0032869 78 0.035
cerebral cortex development GO:0021987 86 0.035
wnt signaling pathway GO:0016055 188 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.034
nitrogen compound transport GO:0071705 271 0.034
cytoplasmic transport GO:0016482 234 0.034
Human
regulation of cell growth GO:0001558 91 0.034
regulation of system process GO:0044057 200 0.034
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.034
regulation of ion transport GO:0043269 215 0.034
cation homeostasis GO:0055080 212 0.034
axon ensheathment GO:0008366 76 0.033
metal ion homeostasis GO:0055065 189 0.033
cellular ketone metabolic process GO:0042180 84 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.033
Human
cellular response to growth factor stimulus GO:0071363 197 0.033
Human
glucose homeostasis GO:0042593 128 0.033
regulation of hydrolase activity GO:0051336 246 0.032
Human Mouse
muscle tissue development GO:0060537 308 0.032
response to lipopolysaccharide GO:0032496 128 0.032
neuron projection guidance GO:0097485 141 0.032
positive regulation of apoptotic process GO:0043065 217 0.032
negative regulation of neuron differentiation GO:0045665 101 0.032
sensory organ morphogenesis GO:0090596 242 0.032
rac protein signal transduction GO:0016601 13 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.031
gtp catabolic process GO:0006184 143 0.031
negative regulation of molecular function GO:0044092 258 0.031
Human Mouse
cellular response to hormone stimulus GO:0032870 150 0.031
regulation of transmembrane transport GO:0034762 128 0.031
actin cytoskeleton organization GO:0030036 220 0.031
protein kinase b signaling GO:0043491 74 0.030
cellular response to peptide GO:1901653 92 0.030
regulation of cellular component biogenesis GO:0044087 181 0.030
Mouse
ensheathment of neurons GO:0007272 76 0.030
response to peptide GO:1901652 136 0.030
microtubule based process GO:0007017 236 0.030
cellular homeostasis GO:0019725 240 0.030
positive regulation of hydrolase activity GO:0051345 148 0.030
positive regulation of neuron differentiation GO:0045666 141 0.029
positive regulation of rho gtpase activity GO:0032321 41 0.029
macromolecule catabolic process GO:0009057 281 0.029
regulation of homeostatic process GO:0032844 182 0.029
cellular response to peptide hormone stimulus GO:0071375 92 0.029
carbohydrate derivative biosynthetic process GO:1901137 183 0.029
cellular chemical homeostasis GO:0055082 215 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
regulation of reactive oxygen species metabolic process GO:2000377 40 0.029
cellular lipid metabolic process GO:0044255 323 0.028
lipid transport GO:0006869 98 0.028
detection of stimulus GO:0051606 84 0.028
positive regulation of mapk cascade GO:0043410 170 0.028
regulation of lymphocyte activation GO:0051249 240 0.028
regulation of ion transmembrane transporter activity GO:0032412 54 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.028
cellular response to organonitrogen compound GO:0071417 145 0.028
sodium ion transport GO:0006814 73 0.028
regulation of ion homeostasis GO:2000021 64 0.027
calcium ion homeostasis GO:0055074 127 0.027
synaptic transmission glutamatergic GO:0035249 36 0.027
leukocyte differentiation GO:0002521 342 0.027
sensory perception GO:0007600 245 0.027
regulation of organelle organization GO:0033043 289 0.027
dephosphorylation GO:0016311 129 0.027
learning or memory GO:0007611 148 0.026
cell adhesion GO:0007155 329 0.026
carbohydrate metabolic process GO:0005975 230 0.026
glycerolipid metabolic process GO:0046486 122 0.026
pallium development GO:0021543 120 0.026
carboxylic acid biosynthetic process GO:0046394 86 0.026
positive regulation of protein modification process GO:0031401 299 0.026
protein maturation GO:0051604 176 0.026
Mouse
positive regulation of programmed cell death GO:0043068 218 0.026
memory GO:0007613 58 0.026
amine metabolic process GO:0009308 45 0.026
regulation of cellular catabolic process GO:0031329 242 0.025
neuron death GO:0070997 154 0.025
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.025
morphogenesis of embryonic epithelium GO:0016331 159 0.025
positive regulation of cellular catabolic process GO:0031331 148 0.025
protein targeting GO:0006605 143 0.025
peptidyl amino acid modification GO:0018193 336 0.025
positive regulation of cell development GO:0010720 237 0.025
response to molecule of bacterial origin GO:0002237 143 0.025
regulation of secretion by cell GO:1903530 249 0.024
dendrite development GO:0016358 115 0.024
embryonic epithelial tube formation GO:0001838 130 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
regulation of secretion GO:0051046 274 0.024
regulation of vesicle mediated transport GO:0060627 139 0.024
microtubule cytoskeleton organization GO:0000226 157 0.024
negative regulation of neuron projection development GO:0010977 50 0.024
positive regulation of nucleotide metabolic process GO:0045981 114 0.024
muscle cell differentiation GO:0042692 261 0.023
male gamete generation GO:0048232 285 0.023
positive regulation of cell projection organization GO:0031346 95 0.022
regulation of engulfment of apoptotic cell GO:1901074 2 0.022
jnk cascade GO:0007254 72 0.022
neural precursor cell proliferation GO:0061351 121 0.022
immune effector process GO:0002252 321 0.022
organic anion transport GO:0015711 137 0.022
regulation of rho gtpase activity GO:0032319 58 0.022
g protein coupled receptor signaling pathway GO:0007186 243 0.022
Human
myelination GO:0042552 74 0.022
regulation of ion transmembrane transport GO:0034765 119 0.022
axon guidance GO:0007411 141 0.022
spermatogenesis GO:0007283 284 0.022
response to oxidative stress GO:0006979 123 0.022
rhythmic process GO:0048511 174 0.022
endomembrane system organization GO:0010256 147 0.022
regionalization GO:0003002 337 0.021
regulation of transporter activity GO:0032409 57 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
apoptotic signaling pathway GO:0097190 306 0.021
Human
organic hydroxy compound metabolic process GO:1901615 203 0.021
carbohydrate biosynthetic process GO:0016051 74 0.021
cellular response to cytokine stimulus GO:0071345 189 0.021
microtubule based movement GO:0007018 84 0.021
regulation of endocytosis GO:0030100 69 0.021
actin filament based movement GO:0030048 23 0.021
exocytosis GO:0006887 121 0.021
organic acid biosynthetic process GO:0016053 86 0.021
regulation of nucleotide catabolic process GO:0030811 122 0.021
epithelial tube morphogenesis GO:0060562 303 0.020
angiogenesis GO:0001525 201 0.020
lipid biosynthetic process GO:0008610 179 0.020
response to radiation GO:0009314 165 0.020
plasma membrane organization GO:0007009 90 0.020
positive regulation of neuron projection development GO:0010976 79 0.020
regulation of kinase activity GO:0043549 249 0.020
Mouse
regulation of metal ion transport GO:0010959 106 0.020
cellular component assembly involved in morphogenesis GO:0010927 139 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.020
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.020
organelle assembly GO:0070925 177 0.020
protein catabolic process GO:0030163 221 0.020
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.019
locomotory behavior GO:0007626 195 0.019
divalent inorganic cation homeostasis GO:0072507 138 0.019
alcohol metabolic process GO:0006066 116 0.019
endocytosis GO:0006897 168 0.019
Human
skeletal muscle organ development GO:0060538 163 0.019
regulation of synaptic transmission glutamatergic GO:0051966 19 0.019
cellular ion homeostasis GO:0006873 165 0.019
peptidyl serine modification GO:0018209 83 0.019
regulation of anatomical structure size GO:0090066 178 0.019
regulation of neuron death GO:1901214 134 0.018
Mouse
circadian regulation of gene expression GO:0032922 48 0.018
regulation of ral gtpase activity GO:0032315 4 0.018
response to organonitrogen compound GO:0010243 246 0.018
regulation of membrane depolarization GO:0003254 11 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
Mouse
regulation of cellular response to growth factor stimulus GO:0090287 82 0.018
regulation of neural precursor cell proliferation GO:2000177 70 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
negative regulation of phosphorus metabolic process GO:0010563 184 0.018
Mouse
cell division GO:0051301 120 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
regulation of hormone levels GO:0010817 211 0.018
canonical wnt signaling pathway GO:0060070 130 0.018
nerve development GO:0021675 67 0.018
actin filament organization GO:0007015 113 0.017
organic acid transport GO:0015849 101 0.017
peripheral nervous system development GO:0007422 53 0.017
skin development GO:0043588 220 0.017
maintenance of location GO:0051235 89 0.017
Mouse
oxidation reduction process GO:0055114 342 0.017
regulation of actin cytoskeleton organization GO:0032956 84 0.017
regulation of neurotransmitter levels GO:0001505 87 0.017
glial cell development GO:0021782 54 0.017
cellular protein complex assembly GO:0043623 116 0.017
myeloid cell differentiation GO:0030099 233 0.017
carboxylic acid transport GO:0046942 100 0.017
epithelial tube formation GO:0072175 130 0.017
engulfment of apoptotic cell GO:0043652 3 0.017
organelle localization GO:0051640 179 0.017
cellular metal ion homeostasis GO:0006875 151 0.017
blood circulation GO:0008015 195 0.017
membrane depolarization GO:0051899 64 0.017
cellular protein catabolic process GO:0044257 155 0.017
organic hydroxy compound transport GO:0015850 93 0.017
regulation of protein kinase b signaling GO:0051896 56 0.017
positive regulation of ras protein signal transduction GO:0046579 13 0.016
steroid metabolic process GO:0008202 119 0.016
protein localization to organelle GO:0033365 185 0.016
Mouse
cholesterol metabolic process GO:0008203 56 0.016
positive regulation of nucleotide catabolic process GO:0030813 88 0.016
regulation of actin filament based process GO:0032970 99 0.016
sequestering of calcium ion GO:0051208 18 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
regulation of response to wounding GO:1903034 189 0.016
neural tube formation GO:0001841 108 0.016
lymphocyte differentiation GO:0030098 242 0.016
neuron apoptotic process GO:0051402 142 0.016
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
protein processing GO:0016485 163 0.016
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
Human
sterol metabolic process GO:0016125 58 0.016
lipoprotein metabolic process GO:0042157 43 0.016
sequestering of metal ion GO:0051238 19 0.016
regulation of wnt signaling pathway GO:0030111 123 0.015
response to fibroblast growth factor GO:0071774 47 0.015
monocarboxylic acid biosynthetic process GO:0072330 61 0.015
synapse organization GO:0050808 125 0.015
gliogenesis GO:0042063 141 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
positive regulation of growth GO:0045927 104 0.015
establishment of organelle localization GO:0051656 122 0.015
central nervous system neuron differentiation GO:0021953 162 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
stress activated protein kinase signaling cascade GO:0031098 81 0.015
positive regulation of phagocytosis GO:0050766 26 0.015
homeostasis of number of cells GO:0048872 210 0.015
modification dependent protein catabolic process GO:0019941 133 0.015
negative regulation of growth GO:0045926 99 0.015
protein autophosphorylation GO:0046777 61 0.015
positive regulation of phagocytosis engulfment GO:0060100 3 0.015
morphogenesis of a branching epithelium GO:0061138 193 0.015
cellular response to lipid GO:0071396 145 0.015
connective tissue development GO:0061448 179 0.015
positive regulation of rho protein signal transduction GO:0035025 7 0.015
positive regulation of myelination GO:0031643 5 0.015
appendage development GO:0048736 166 0.015
cell substrate adhesion GO:0031589 130 0.015
fertilization GO:0009566 127 0.015
regulation of axon extension GO:0030516 43 0.015
developmental maturation GO:0021700 193 0.015
developmental cell growth GO:0048588 84 0.015
establishment of protein localization to membrane GO:0090150 54 0.015
primary neural tube formation GO:0014020 95 0.015
neural tube closure GO:0001843 90 0.015
lymphocyte mediated immunity GO:0002449 139 0.014
regulation of myelination GO:0031641 20 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
digestive tract morphogenesis GO:0048546 147 0.014
peptidyl serine phosphorylation GO:0018105 74 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
Mouse
protein complex disassembly GO:0043241 40 0.014
regulation of glucose import GO:0046324 26 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
phagocytosis GO:0006909 66 0.014
regulation of protein kinase activity GO:0045859 232 0.014
Mouse
brain derived neurotrophic factor receptor signaling pathway GO:0031547 3 0.014
circadian rhythm GO:0007623 114 0.014
second messenger mediated signaling GO:0019932 73 0.014
regulation of cell substrate adhesion GO:0010810 73 0.014
positive regulation of ion transport GO:0043270 65 0.014
regulation of cellular response to stress GO:0080135 159 0.014
sensory system development GO:0048880 3 0.014
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.014
glycerophospholipid metabolic process GO:0006650 71 0.014
defecation GO:0030421 1 0.014
positive regulation of rac gtpase activity GO:0032855 14 0.014
negative regulation of cytoskeleton organization GO:0051494 36 0.014
meiotic cell cycle GO:0051321 122 0.014
vesicle organization GO:0016050 60 0.014
regulation of t cell activation GO:0050863 170 0.014
regulation of glucose import in response to insulin stimulus GO:2001273 8 0.014
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.014
tube closure GO:0060606 91 0.014
establishment of tissue polarity GO:0007164 28 0.014
microtubule based transport GO:0010970 50 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
Mouse
cell maturation GO:0048469 127 0.013
regulation of calcium ion transport GO:0051924 69 0.013
positive regulation of organelle organization GO:0010638 128 0.013
intra golgi vesicle mediated transport GO:0006891 1 0.013
muscle cell development GO:0055001 133 0.013
glycoprotein metabolic process GO:0009100 116 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.013
small molecule biosynthetic process GO:0044283 132 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
cell junction maintenance GO:0034331 4 0.013
b cell differentiation GO:0030183 78 0.013
regulation of cell adhesion GO:0030155 154 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
compound eye development GO:0048749 1 0.013
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
response to drug GO:0042493 75 0.013
regulation of protein binding GO:0043393 60 0.013
branching morphogenesis of an epithelial tube GO:0048754 159 0.013
rab protein signal transduction GO:0032482 1 0.013
amino acid transport GO:0006865 61 0.013
adult behavior GO:0030534 135 0.013
neurotransmitter transport GO:0006836 76 0.013
circulatory system process GO:0003013 197 0.013
pharynx development GO:0060465 1 0.013
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.013
skeletal system morphogenesis GO:0048705 203 0.013
cell growth GO:0016049 130 0.013
positive regulation of defense response GO:0031349 124 0.013
glucose import in response to insulin stimulus GO:0044381 8 0.013
synapse assembly GO:0007416 56 0.013
macromolecular complex disassembly GO:0032984 43 0.013
b cell activation GO:0042113 161 0.013
smoothened signaling pathway GO:0007224 105 0.013
muscle contraction GO:0006936 101 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
negative regulation of monocyte extravasation GO:2000438 1 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
negative regulation of immune system process GO:0002683 209 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
regulation of cellular response to insulin stimulus GO:1900076 30 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
autonomic nervous system development GO:0048483 43 0.012
photoreceptor cell development GO:0042461 40 0.012
protein localization to plasma membrane GO:0072659 57 0.012
regulation of protein localization GO:0032880 231 0.012
multi multicellular organism process GO:0044706 109 0.012
regulation of defense response GO:0031347 233 0.012
tube formation GO:0035148 140 0.012
atp metabolic process GO:0046034 75 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
Mouse
wound healing GO:0042060 157 0.012
actin cytoskeleton reorganization GO:0031532 21 0.012
nerve growth factor signaling pathway GO:0038180 3 0.012
Human
regulation of synaptic plasticity GO:0048167 87 0.012
cellularization GO:0007349 1 0.012
midgut development GO:0007494 4 0.012
regulation of cell activation GO:0050865 289 0.012
regulation of multi organism process GO:0043900 111 0.012
establishment of vesicle localization GO:0051650 81 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
embryonic genitalia morphogenesis GO:0030538 4 0.012
pigmentation GO:0043473 71 0.012
glial cell differentiation GO:0010001 131 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
oocyte axis specification GO:0007309 2 0.012
odontogenesis GO:0042476 78 0.012
neural tube development GO:0021915 160 0.012
negative regulation of organelle organization GO:0010639 90 0.012
synaptic vesicle localization GO:0097479 59 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
positive regulation of tor signaling GO:0032008 3 0.012
establishment of planar polarity GO:0001736 28 0.012
lateral inhibition GO:0046331 1 0.012
adult locomotory behavior GO:0008344 91 0.012
t cell activation GO:0042110 289 0.012
cerebellar granule cell precursor tangential migration GO:0021935 1 0.011
gland development GO:0048732 330 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
cofactor metabolic process GO:0051186 80 0.011
limb development GO:0060173 166 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
lipid localization GO:0010876 126 0.011
apical constriction GO:0003383 4 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
calcium mediated signaling GO:0019722 46 0.011
leukocyte migration GO:0050900 124 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011

Sort1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.058
disease of anatomical entity DOID:7 0 0.058
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
organ system cancer DOID:0050686 0 0.024
disease of metabolism DOID:0014667 0 0.018
neuropathy DOID:870 0 0.017
central nervous system disease DOID:331 0 0.017
neurodegenerative disease DOID:1289 0 0.014
immune system disease DOID:2914 0 0.014
inherited metabolic disorder DOID:655 0 0.012
hematologic cancer DOID:2531 0 0.012
immune system cancer DOID:0060083 0 0.012