Mus musculus

184 known processes

Sos2

son of sevenless homolog 2 (Drosophila)

(Aliases: SOS-2,mSOS-2)

Sos2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
guanosine containing compound metabolic process GO:1901068 144 0.611
golgi to endosome transport GO:0006895 3 0.368
early endosome to late endosome transport GO:0045022 2 0.352
dephosphorylation GO:0016311 129 0.276
regulation of hydrolase activity GO:0051336 246 0.249
plus end directed organelle transport along microtubule GO:0072386 2 0.215
protein localization to chromatin GO:0071168 3 0.209
plus end directed vesicle transport along microtubule GO:0072383 2 0.208
organic cyclic compound catabolic process GO:1901361 295 0.203
nucleotide catabolic process GO:0009166 217 0.168
t cell activation GO:0042110 289 0.168
endomembrane system organization GO:0010256 147 0.157
regulation of cytoplasmic translation GO:2000765 4 0.150
regulation of cellular catabolic process GO:0031329 242 0.149
covalent chromatin modification GO:0016569 163 0.146
regionalization GO:0003002 337 0.145
ras protein signal transduction GO:0007265 77 0.131
Yeast Mouse Fly
maintenance of location GO:0051235 89 0.131
regulation of neuronal synaptic plasticity GO:0048168 30 0.130
Mouse
protein modification by small protein conjugation GO:0032446 187 0.124
chromatin modification GO:0016568 187 0.122
gtp catabolic process GO:0006184 143 0.122
carbohydrate derivative catabolic process GO:1901136 231 0.117
striated muscle tissue development GO:0014706 293 0.116
leukocyte differentiation GO:0002521 342 0.116
cellular lipid metabolic process GO:0044255 323 0.115
mesodermal cell migration GO:0008078 4 0.115
cell adhesion GO:0007155 329 0.112
Mouse
regulation of nucleoside metabolic process GO:0009118 130 0.110
regulation of gtp catabolic process GO:0033124 113 0.106
purine ribonucleotide metabolic process GO:0009150 290 0.102
positive regulation of mrna polyadenylation GO:1900365 1 0.100
lymphocyte differentiation GO:0030098 242 0.099
actin cytoskeleton organization GO:0030036 220 0.097
Fly
organonitrogen compound catabolic process GO:1901565 264 0.095
cellular response to organonitrogen compound GO:0071417 145 0.093
regulation of purine nucleotide catabolic process GO:0033121 122 0.090
regulation of secretion GO:0051046 274 0.085
alcohol metabolic process GO:0006066 116 0.082
positive regulation of gtp catabolic process GO:0033126 85 0.082
organic hydroxy compound metabolic process GO:1901615 203 0.079
purine nucleoside catabolic process GO:0006152 205 0.079
ribose phosphate metabolic process GO:0019693 291 0.077
nuclear division GO:0000280 158 0.075
ribonucleotide catabolic process GO:0009261 208 0.075
response to organonitrogen compound GO:0010243 246 0.074
protein modification by small protein conjugation or removal GO:0070647 207 0.072
regulation of nucleotide metabolic process GO:0006140 169 0.069
axonogenesis GO:0007409 274 0.069
Fly
positive regulation of muscle adaptation GO:0014744 2 0.067
chromatin organization GO:0006325 206 0.065
regulation of synaptic plasticity GO:0048167 87 0.064
Mouse
regulation of nucleotide catabolic process GO:0030811 122 0.063
myeloid cell differentiation GO:0030099 233 0.063
regulation of purine nucleotide metabolic process GO:1900542 169 0.062
regulation of transforming growth factor beta2 production GO:0032909 2 0.061
muscle tissue development GO:0060537 308 0.060
positive regulation of myeloid cell apoptotic process GO:0033034 4 0.060
regulation of secretion by cell GO:1903530 249 0.059
macromolecule catabolic process GO:0009057 281 0.059
negative regulation of mitotic cell cycle GO:0045930 58 0.058
Fly
regulation of cell cycle GO:0051726 281 0.057
Yeast Fly
negative regulation of phosphate metabolic process GO:0045936 184 0.056
Mouse
mitochondrion transport along microtubule GO:0047497 3 0.054
positive regulation of secretion GO:0051047 130 0.054
dendrite development GO:0016358 115 0.054
positive regulation of nfat protein import into nucleus GO:0051533 1 0.054
regulation of organelle organization GO:0033043 289 0.054
exocytosis GO:0006887 121 0.053
ribonucleotide metabolic process GO:0009259 291 0.053
organelle localization GO:0051640 179 0.053
purine ribonucleoside catabolic process GO:0046130 205 0.053
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.051
regulation of exocytosis GO:0017157 61 0.051
cell type specific apoptotic process GO:0097285 268 0.051
guanosine containing compound catabolic process GO:1901069 144 0.051
chemotaxis GO:0006935 247 0.049
Fly
modification dependent macromolecule catabolic process GO:0043632 133 0.048
intracellular protein transport GO:0006886 204 0.048
purine nucleoside triphosphate metabolic process GO:0009144 226 0.048
neurotransmitter secretion GO:0007269 62 0.048
mitotic cell cycle GO:0000278 195 0.045
Yeast Fly
gonad development GO:0008406 141 0.045
immunoglobulin transcytosis in epithelial cells GO:0002414 2 0.045
g1 s transition of mitotic cell cycle GO:0000082 57 0.045
Yeast Fly
protein catabolic process GO:0030163 221 0.045
ribonucleoside metabolic process GO:0009119 245 0.045
nucleoside triphosphate catabolic process GO:0009143 205 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.044
single organismal cell cell adhesion GO:0016337 131 0.044
Mouse
heterocycle catabolic process GO:0046700 280 0.044
positive regulation of hydrolase activity GO:0051345 148 0.044
cellular amino acid metabolic process GO:0006520 103 0.044
myotube cell development GO:0014904 60 0.044
nucleoside metabolic process GO:0009116 246 0.043
cation transport GO:0006812 399 0.043
regulation of cell cycle process GO:0010564 160 0.042
Yeast Fly
microtubule based process GO:0007017 236 0.042
protein processing GO:0016485 163 0.041
lipid storage GO:0019915 36 0.041
regulation of engulfment of apoptotic cell GO:1901074 2 0.041
peptidyl amino acid modification GO:0018193 336 0.041
calcium ion dependent exocytosis GO:0017156 35 0.040
positive regulation of protein phosphorylation GO:0001934 242 0.040
nucleoside triphosphate metabolic process GO:0009141 230 0.040
organ or tissue specific immune response GO:0002251 13 0.040
nucleoside catabolic process GO:0009164 206 0.040
intracellular lipid transport GO:0032365 3 0.040
protein ubiquitination GO:0016567 171 0.040
positive regulation of protein modification process GO:0031401 299 0.039
positive regulation of nucleoside metabolic process GO:0045979 91 0.039
positive regulation of secretion by cell GO:1903532 114 0.039
fertilization GO:0009566 127 0.039
phospholipid metabolic process GO:0006644 87 0.038
regulation of establishment of protein localization GO:0070201 181 0.038
lipid localization GO:0010876 126 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
organophosphate catabolic process GO:0046434 232 0.037
negative regulation of intracellular signal transduction GO:1902532 167 0.037
Mouse
purine nucleoside metabolic process GO:0042278 241 0.037
stem cell differentiation GO:0048863 268 0.036
ribonucleoside triphosphate metabolic process GO:0009199 220 0.036
glucose homeostasis GO:0042593 128 0.036
metal ion homeostasis GO:0055065 189 0.036
peptide secretion GO:0002790 114 0.035
small gtpase mediated signal transduction GO:0007264 97 0.035
myeloid leukocyte differentiation GO:0002573 119 0.035
cardiac muscle hypertrophy in response to stress GO:0014898 10 0.035
neutrophil mediated immunity GO:0002446 19 0.035
meiotic cell cycle GO:0051321 122 0.035
myeloid leukocyte mediated immunity GO:0002444 42 0.034
regulation of protein localization GO:0032880 231 0.034
regulation of neurotransmitter levels GO:0001505 87 0.034
cellular response to insulin stimulus GO:0032869 78 0.034
protein modification by small protein removal GO:0070646 21 0.034
positive regulation of gtpase activity GO:0043547 85 0.034
neuron projection guidance GO:0097485 141 0.033
Fly
regulation of ras protein signal transduction GO:0046578 114 0.033
leukocyte homeostasis GO:0001776 79 0.033
nitrogen compound transport GO:0071705 271 0.032
hematopoietic progenitor cell differentiation GO:0002244 143 0.032
cellular nitrogen compound catabolic process GO:0044270 280 0.032
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 3 0.032
potassium ion transport GO:0006813 52 0.032
blood vessel morphogenesis GO:0048514 285 0.031
cellular protein catabolic process GO:0044257 155 0.031
hormone secretion GO:0046879 128 0.031
digestive tract development GO:0048565 190 0.030
negative regulation of gene expression epigenetic GO:0045814 15 0.030
neuron apoptotic process GO:0051402 142 0.030
purine nucleotide catabolic process GO:0006195 211 0.030
regulation of mapk cascade GO:0043408 248 0.030
Mouse
protein localization to membrane GO:0072657 108 0.030
protein localization to nucleus GO:0034504 121 0.030
modification dependent protein catabolic process GO:0019941 133 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
gtp metabolic process GO:0046039 144 0.029
regulation of androgen receptor signaling pathway GO:0060765 3 0.029
ubiquitin dependent protein catabolic process GO:0006511 129 0.029
positive regulation of sequestering of triglyceride GO:0010890 4 0.029
adaptive immune response GO:0002250 155 0.029
response to insulin GO:0032868 100 0.029
establishment of protein localization to vacuole GO:0072666 4 0.029
negative regulation of phosphorus metabolic process GO:0010563 184 0.028
Mouse
ribonucleoprotein complex subunit organization GO:0071826 28 0.028
regulation of membrane potential GO:0042391 192 0.028
sterol metabolic process GO:0016125 58 0.028
regulation of transferase activity GO:0051338 263 0.027
cytoskeleton dependent intracellular transport GO:0030705 50 0.027
negative regulation of secretion GO:0051048 61 0.027
leukocyte migration GO:0050900 124 0.027
response to endoplasmic reticulum stress GO:0034976 53 0.027
mitotic cell cycle process GO:1903047 159 0.027
Yeast Fly
olfactory learning GO:0008355 2 0.026
synaptic transmission GO:0007268 329 0.026
Mouse
membrane organization GO:0061024 245 0.026
positive regulation of ras gtpase activity GO:0032320 65 0.026
regulation of protein localization to nucleus GO:1900180 60 0.026
fatty acid biosynthetic process GO:0006633 41 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
regulation of protein processing GO:0070613 96 0.026
single species biofilm formation GO:0044010 1 0.026
skeletal muscle fiber development GO:0048741 58 0.026
sensory organ morphogenesis GO:0090596 242 0.026
neurotransmitter transport GO:0006836 76 0.026
vesicle docking GO:0048278 7 0.026
protein k63 linked deubiquitination GO:0070536 1 0.026
establishment of vesicle localization GO:0051650 81 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
cellular homeostasis GO:0019725 240 0.025
regulation of protein kinase b signaling GO:0051896 56 0.024
Mouse
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.024
positive regulation of cell death GO:0010942 224 0.024
regulation of autophagy GO:0010506 30 0.024
neuron neuron synaptic transmission GO:0007270 69 0.024
insulin secretion GO:0030073 89 0.024
leukocyte mediated immunity GO:0002443 174 0.024
glycosyl compound catabolic process GO:1901658 206 0.024
positive regulation of engulfment of apoptotic cell GO:1901076 1 0.024
establishment of organelle localization GO:0051656 122 0.024
organelle fission GO:0048285 170 0.024
regulation of neurotransmitter secretion GO:0046928 29 0.024
positive regulation of protein binding GO:0032092 29 0.023
cell cycle switching GO:0060184 1 0.023
response to oxidative stress GO:0006979 123 0.023
skeletal muscle organ development GO:0060538 163 0.023
protein methylation GO:0006479 81 0.023
positive regulation of cell projection organization GO:0031346 95 0.023
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.023
positive regulation of mrna 3 end processing GO:0031442 5 0.023
negative regulation of protein maturation GO:1903318 79 0.023
regulation of neuron differentiation GO:0045664 281 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.022
regulation of postsynaptic membrane potential GO:0060078 48 0.022
regulation of skeletal muscle adaptation GO:0014733 12 0.022
female meiosis chromosome segregation GO:0016321 1 0.022
digestive system development GO:0055123 200 0.022
regulation of cellular amine metabolic process GO:0033238 20 0.022
negative regulation of purine nucleotide catabolic process GO:0033122 9 0.022
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.022
negative regulation of translation GO:0017148 22 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
limb morphogenesis GO:0035108 149 0.022
cellular ion homeostasis GO:0006873 165 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
protein localization to plasma membrane GO:0072659 57 0.022
multicellular organism growth GO:0035264 161 0.021
cell division GO:0051301 120 0.021
lymphocyte proliferation GO:0046651 164 0.021
cellular metal ion homeostasis GO:0006875 151 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
homeostasis of number of cells GO:0048872 210 0.021
regulation of proteolysis GO:0030162 164 0.021
skeletal muscle cell differentiation GO:0035914 66 0.021
regulation of lymphocyte proliferation GO:0050670 117 0.021
negative regulation of synaptic transmission gabaergic GO:0032229 2 0.021
sensory perception GO:0007600 245 0.020
i kappab kinase nf kappab signaling GO:0007249 85 0.020
negative regulation of neuron death GO:1901215 98 0.020
cell substrate adhesion GO:0031589 130 0.020
regulation of t cell mediated cytotoxicity GO:0001914 18 0.020
response to peptide GO:1901652 136 0.020
negative regulation of protein processing GO:0010955 79 0.020
multi organism behavior GO:0051705 62 0.020
Worm
positive regulation of apoptotic cell clearance GO:2000427 3 0.019
regulation of jnk cascade GO:0046328 62 0.019
transforming growth factor beta2 production GO:0032906 2 0.019
mapk cascade GO:0000165 281 0.019
Mouse
carbohydrate homeostasis GO:0033500 128 0.019
protein localization to organelle GO:0033365 185 0.019
male gamete generation GO:0048232 285 0.019
regulation of neuron projection development GO:0010975 169 0.019
regulation of cell size GO:0008361 72 0.019
body morphogenesis GO:0010171 45 0.019
Worm
regulation of cytoskeleton organization GO:0051493 122 0.019
generation of precursor metabolites and energy GO:0006091 103 0.019
protein localization to endosome GO:0036010 2 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
actin filament bundle assembly GO:0051017 40 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
peptidyl serine modification GO:0018209 83 0.018
cellular response to peptide GO:1901653 92 0.018
regulation of cell division GO:0051302 76 0.018
protein deubiquitination GO:0016579 19 0.018
negative regulation of neuron apoptotic process GO:0043524 92 0.018
mitochondrion organization GO:0007005 134 0.018
response to light stimulus GO:0009416 135 0.018
cytokinetic process GO:0032506 2 0.018
response to fibroblast growth factor GO:0071774 47 0.018
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.018
Mouse
amine metabolic process GO:0009308 45 0.018
actomyosin structure organization GO:0031032 56 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
activation of immune response GO:0002253 138 0.018
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.018
cell activation involved in immune response GO:0002263 126 0.018
learning or memory GO:0007611 148 0.018
gene silencing GO:0016458 38 0.017
metencephalon development GO:0022037 89 0.017
regulation of cell killing GO:0031341 40 0.017
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.017
positive regulation of phagocytosis engulfment GO:0060100 3 0.017
vesicle transport along microtubule GO:0047496 9 0.017
single organism cell adhesion GO:0098602 156 0.017
Mouse
regulation of protein maturation GO:1903317 96 0.017
glycoprotein biosynthetic process GO:0009101 89 0.017
negative regulation of proteolysis GO:0045861 74 0.017
regulation of ras gtpase activity GO:0032318 88 0.017
female gamete generation GO:0007292 74 0.017
Worm
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.017
Mouse
protein retention in golgi apparatus GO:0045053 1 0.017
response to inorganic substance GO:0010035 96 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
regulation of lipid metabolic process GO:0019216 118 0.017
regulation of neuron death GO:1901214 134 0.017
negative regulation of nucleoside metabolic process GO:0045978 11 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
steroid metabolic process GO:0008202 119 0.016
retrograde vesicle mediated transport golgi to er GO:0006890 1 0.016
regulation of intracellular transport GO:0032386 159 0.016
positive regulation of macroautophagy GO:0016239 3 0.016
striated muscle cell development GO:0055002 125 0.016
negative regulation of cell cycle GO:0045786 123 0.016
Fly
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
cellular response to peptide hormone stimulus GO:0071375 92 0.016
granulocyte activation GO:0036230 10 0.016
mrna 3 end processing GO:0031124 16 0.016
monocarboxylic acid biosynthetic process GO:0072330 61 0.016
protein localization to vacuole GO:0072665 4 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.015
peptide hormone secretion GO:0030072 109 0.015
locomotory behavior GO:0007626 195 0.015
regulation of kinase activity GO:0043549 249 0.015
muscle cell differentiation GO:0042692 261 0.015
central nervous system neuron differentiation GO:0021953 162 0.015
female meiotic division GO:0007143 21 0.015
small molecule biosynthetic process GO:0044283 132 0.015
lipid transport GO:0006869 98 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.015
regulation of myeloid cell differentiation GO:0045637 96 0.015
formation of primary germ layer GO:0001704 77 0.015
regulation of cellular component size GO:0032535 121 0.015
regulation of t cell proliferation GO:0042129 92 0.015
ossification GO:0001503 216 0.015
regulation of cellular ketone metabolic process GO:0010565 66 0.015
synaptic vesicle endocytosis GO:0048488 19 0.015
antibacterial peptide biosynthetic process GO:0002780 2 0.014
microtubule based movement GO:0007018 84 0.014
energy derivation by oxidation of organic compounds GO:0015980 77 0.014
immune response regulating signaling pathway GO:0002764 125 0.014
mitochondrial genome maintenance GO:0000002 15 0.014
localization within membrane GO:0051668 4 0.014
cytoplasmic transport GO:0016482 234 0.014
organelle assembly GO:0070925 177 0.014
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.014
positive regulation of ubiquitin protein transferase activity GO:0051443 4 0.014
bone morphogenesis GO:0060349 78 0.014
sensory perception of sound GO:0007605 97 0.014
positive regulation of smooth muscle cell migration GO:0014911 4 0.014
cellular response to acid chemical GO:0071229 68 0.014
protein polymerization GO:0051258 57 0.014
regulation of protein transport GO:0051223 163 0.014
response to radiation GO:0009314 165 0.014
negative regulation of cell cycle process GO:0010948 69 0.014
Fly
multicellular organismal reproductive behavior GO:0033057 23 0.014
Worm
nucleotide excision repair GO:0006289 13 0.014
peptide transport GO:0015833 133 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
somite development GO:0061053 81 0.014
carbohydrate metabolic process GO:0005975 230 0.014
positive regulation of growth GO:0045927 104 0.014
negative regulation of secretion by cell GO:1903531 54 0.013
positive regulation of exocytosis GO:0045921 20 0.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.013
cellular glucose homeostasis GO:0001678 52 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
regulation of stress activated mapk cascade GO:0032872 69 0.013
regulation of cellular amino acid metabolic process GO:0006521 5 0.013
meiotic nuclear division GO:0007126 115 0.013
membrane fusion GO:0061025 38 0.013
forebrain development GO:0030900 302 0.013
oogenesis GO:0048477 56 0.013
membrane lipid metabolic process GO:0006643 53 0.013
vesicle localization GO:0051648 86 0.013
segmentation GO:0035282 93 0.013
calcium ion homeostasis GO:0055074 127 0.013
positive regulation of cardiac muscle hypertrophy GO:0010613 2 0.013
immune effector process GO:0002252 321 0.013
regulation of protein import into nucleus GO:0042306 52 0.013
cellular chemical homeostasis GO:0055082 215 0.013
cell growth GO:0016049 130 0.013
regulation of cell migration GO:0030334 219 0.013
regulation of protein stability GO:0031647 52 0.013
glycerophospholipid metabolic process GO:0006650 71 0.013
neuron death GO:0070997 154 0.013
growth plate cartilage chondrocyte growth GO:0003430 2 0.013
response to peptide hormone GO:0043434 127 0.013
synaptic vesicle recycling GO:0036465 19 0.013
positive regulation of protein catabolic process GO:0045732 60 0.013
developmental maturation GO:0021700 193 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
neutrophil degranulation GO:0043312 6 0.013
response to ischemia GO:0002931 14 0.013
positive regulation of nervous system development GO:0051962 221 0.012
establishment of mitochondrion localization GO:0051654 4 0.012
neural precursor cell proliferation GO:0061351 121 0.012
Mouse
gastrulation GO:0007369 116 0.012
axon target recognition GO:0007412 4 0.012
b cell activation GO:0042113 161 0.012
phosphatidylinositol metabolic process GO:0046488 45 0.012
sequestering of triglyceride GO:0030730 6 0.012
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.012
methylation GO:0032259 134 0.012
vesicle docking involved in exocytosis GO:0006904 7 0.012
nucleotide metabolic process GO:0009117 332 0.012
endocytosis GO:0006897 168 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
regulation of feeding behavior GO:0060259 3 0.012
regulation of leukocyte apoptotic process GO:2000106 56 0.012
regulation of hormone levels GO:0010817 211 0.012
body fluid secretion GO:0007589 53 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
Yeast Fly
lipid biosynthetic process GO:0008610 179 0.012
stress activated mapk cascade GO:0051403 80 0.012
meiosis i GO:0007127 60 0.012
cellular amine metabolic process GO:0044106 44 0.012
myotube differentiation GO:0014902 105 0.012
appendage morphogenesis GO:0035107 149 0.012
Fly
cellularization GO:0007349 1 0.012
leukocyte apoptotic process GO:0071887 71 0.011
regulation of cell cycle phase transition GO:1901987 77 0.011
Yeast Fly
regulation of nucleocytoplasmic transport GO:0046822 73 0.011
somitogenesis GO:0001756 69 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
leukocyte tethering or rolling GO:0050901 3 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
transmembrane transport GO:0055085 412 0.011
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
cytokine production GO:0001816 319 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
regulation of cell motility GO:2000145 236 0.011
positive regulation of defense response GO:0031349 124 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
Mouse
circadian rhythm GO:0007623 114 0.011
regulation of ion transport GO:0043269 215 0.011
Mouse
granulocyte differentiation GO:0030851 17 0.011
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 10 0.011
Mouse
neural tube closure GO:0001843 90 0.011
carbohydrate transport GO:0008643 62 0.011
cellular response to glucose stimulus GO:0071333 45 0.011
positive regulation of mrna metabolic process GO:1903313 17 0.011
ventricular cardiac myofibril assembly GO:0055005 3 0.011
telencephalon development GO:0021537 186 0.011
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.011
regulation of endocytosis GO:0030100 69 0.011
immune response activating signal transduction GO:0002757 116 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
regulation of transcription factor import into nucleus GO:0042990 24 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
reproductive behavior GO:0019098 32 0.011
Worm
regulation of intracellular protein transport GO:0033157 82 0.011
multicellular organismal aging GO:0010259 24 0.011
regulation of cell adhesion GO:0030155 154 0.011
ensheathment of neurons GO:0007272 76 0.011
transition metal ion homeostasis GO:0055076 54 0.010
negative regulation of adaptive immune response GO:0002820 25 0.010
regulation of cytokine production GO:0001817 266 0.010
cation homeostasis GO:0055080 212 0.010
regulation of ossification GO:0030278 112 0.010
receptor internalization GO:0031623 16 0.010
cognition GO:0050890 149 0.010
spermatogenesis GO:0007283 284 0.010
cardiac muscle hypertrophy GO:0003300 23 0.010
sterol transport GO:0015918 38 0.010
negative regulation of exocytosis GO:0045920 12 0.010
endoderm development GO:0007492 45 0.010
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.010
rho protein signal transduction GO:0007266 32 0.010
regulation of myeloid leukocyte differentiation GO:0002761 58 0.010
blastocyst development GO:0001824 80 0.010
protein alkylation GO:0008213 81 0.010
regulation of nuclear division GO:0051783 56 0.010
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.010

Sos2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.570
disease of anatomical entity DOID:7 0 0.570
eye and adnexa disease DOID:1492 0 0.570
nervous system disease DOID:863 0 0.570
eye disease DOID:5614 0 0.570
retinal disease DOID:5679 0 0.055
retinal degeneration DOID:8466 0 0.055
cone rod dystrophy DOID:0050572 0 0.041
disease of cellular proliferation DOID:14566 0 0.022
large intestine cancer DOID:5672 0 0.017
colon cancer DOID:219 0 0.017
gastrointestinal system cancer DOID:3119 0 0.017
intestinal cancer DOID:10155 0 0.017
cancer DOID:162 0 0.017
organ system cancer DOID:0050686 0 0.017
colorectal cancer DOID:9256 0 0.017
colon carcinoma DOID:1520 0 0.011