Mus musculus

140 known processes

Sp1

trans-acting transcription factor 1

(Aliases: AI845540,Sp1-1,AA450830,1110003E12Rik)

Sp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ossification GO:0001503 216 0.833
chromatin organization GO:0006325 206 0.775
regulation of chromatin silencing GO:0031935 2 0.771
natural killer cell differentiation GO:0001779 21 0.740
Mouse
regulation of cell cycle GO:0051726 281 0.722
leukocyte differentiation GO:0002521 342 0.696
Mouse
dna metabolic process GO:0006259 303 0.659
camera type eye development GO:0043010 266 0.617
blastocyst development GO:0001824 80 0.593
regulation of cell cycle process GO:0010564 160 0.565
histone modification GO:0016570 159 0.530
embryonic skeletal system development GO:0048706 120 0.499
monocyte differentiation GO:0030224 9 0.498
Mouse
cellular response to abiotic stimulus GO:0071214 56 0.491
histone h4 deacetylation GO:0070933 4 0.488
fibroblast proliferation GO:0048144 35 0.487
Mouse
trophectodermal cell differentiation GO:0001829 21 0.481
myeloid leukocyte differentiation GO:0002573 119 0.474
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.451
circulatory system process GO:0003013 197 0.443
Mouse
gland development GO:0048732 330 0.436
protein deacetylation GO:0006476 32 0.429
muscle cell differentiation GO:0042692 261 0.411
embryonic organ morphogenesis GO:0048562 276 0.406
regulation of heart contraction GO:0008016 77 0.397
Mouse
skeletal system development GO:0001501 356 0.396
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.394
limb morphogenesis GO:0035108 149 0.380
Mouse
germ cell development GO:0007281 185 0.376
circadian regulation of gene expression GO:0032922 48 0.374
negative regulation of protein metabolic process GO:0051248 282 0.357
negative regulation of cellular protein metabolic process GO:0032269 247 0.349
t cell activation GO:0042110 289 0.345
Mouse
placenta development GO:0001890 140 0.345
myeloid cell differentiation GO:0030099 233 0.345
blood circulation GO:0008015 195 0.333
Mouse
cellular amino acid metabolic process GO:0006520 103 0.322
hematopoietic progenitor cell differentiation GO:0002244 143 0.320
response to organic cyclic compound GO:0014070 198 0.306
megakaryocyte differentiation GO:0030219 26 0.301
lymphocyte differentiation GO:0030098 242 0.284
Mouse
embryonic appendage morphogenesis GO:0035113 126 0.278
Mouse
heart contraction GO:0060047 93 0.276
Mouse
positive regulation of apoptotic process GO:0043065 217 0.265
covalent chromatin modification GO:0016569 163 0.262
embryonic process involved in female pregnancy GO:0060136 7 0.258
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.252
macromolecule catabolic process GO:0009057 281 0.245
cellular response to radiation GO:0071478 28 0.244
respiratory system development GO:0060541 190 0.232
regulation of transcription during meiosis GO:0051037 1 0.226
positive regulation of programmed cell death GO:0043068 218 0.225
cellular response to growth factor stimulus GO:0071363 197 0.224
myeloid cell homeostasis GO:0002262 114 0.219
response to growth factor GO:0070848 198 0.216
cellular amine metabolic process GO:0044106 44 0.212
natural killer cell activation GO:0030101 44 0.212
Mouse
negative regulation of chromatin silencing GO:0031936 1 0.209
generation of precursor metabolites and energy GO:0006091 103 0.209
muscle tissue development GO:0060537 308 0.198
regionalization GO:0003002 337 0.191
Mouse
negative regulation of protein modification process GO:0031400 163 0.189
protein acylation GO:0043543 64 0.186
posttranscriptional regulation of gene expression GO:0010608 155 0.184
regulation of cell cycle phase transition GO:1901987 77 0.183
wound healing GO:0042060 157 0.182
histone deacetylation GO:0016575 26 0.180
regulation of blood circulation GO:1903522 93 0.177
Mouse
positive regulation of cell death GO:0010942 224 0.176
negative regulation of neuron apoptotic process GO:0043524 92 0.171
development of primary sexual characteristics GO:0045137 143 0.171
embryonic placenta development GO:0001892 98 0.169
neural tube development GO:0021915 160 0.169
digestive system development GO:0055123 200 0.169
cardiocyte differentiation GO:0035051 87 0.165
b cell activation GO:0042113 161 0.161
Mouse
stem cell differentiation GO:0048863 268 0.160
regulation of protein maturation GO:1903317 96 0.157
circadian rhythm GO:0007623 114 0.156
protein processing GO:0016485 163 0.155
lipid biosynthetic process GO:0008610 179 0.155
morphogenesis of a branching epithelium GO:0061138 193 0.154
nucleoside phosphate metabolic process GO:0006753 338 0.152
negative regulation of gene expression epigenetic GO:0045814 15 0.149
response to inorganic substance GO:0010035 96 0.149
negative regulation of cell cycle phase transition GO:1901988 48 0.147
regulation of fat cell differentiation GO:0045598 81 0.143
gonad development GO:0008406 141 0.142
lung development GO:0030324 164 0.142
response to radiation GO:0009314 165 0.142
apoptotic signaling pathway GO:0097190 306 0.140
cellular ketone metabolic process GO:0042180 84 0.137
organic hydroxy compound metabolic process GO:1901615 203 0.136
viral transcription GO:0019083 3 0.136
Human
male meiosis GO:0007140 37 0.136
modification dependent macromolecule catabolic process GO:0043632 133 0.132
female gamete generation GO:0007292 74 0.131
nuclear transcribed mrna poly a tail shortening GO:0000289 7 0.131
mrna catabolic process GO:0006402 22 0.129
posttranscriptional gene silencing GO:0016441 10 0.127
cellular response to dna damage stimulus GO:0006974 207 0.126
multicellular organism growth GO:0035264 161 0.126
Mouse
chromatin silencing GO:0006342 15 0.125
cellular response to external stimulus GO:0071496 88 0.123
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 12 0.123
epithelial tube morphogenesis GO:0060562 303 0.122
gene silencing GO:0016458 38 0.121
Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.120
rhythmic process GO:0048511 174 0.120
regulation of defense response GO:0031347 233 0.120
histone h4 k12 acetylation GO:0043983 2 0.119
chromatin silencing at rdna GO:0000183 3 0.119
cellular nitrogen compound catabolic process GO:0044270 280 0.118
b cell differentiation GO:0030183 78 0.117
Mouse
organelle fission GO:0048285 170 0.116
regulation of cellular amine metabolic process GO:0033238 20 0.115
male gamete generation GO:0048232 285 0.114
regulation of protein stability GO:0031647 52 0.114
regulation of protein processing GO:0070613 96 0.113
regulation of cellular amino acid metabolic process GO:0006521 5 0.111
sensory organ morphogenesis GO:0090596 242 0.110
spermatogenesis GO:0007283 284 0.109
rna interference GO:0016246 2 0.105
chromatin modification GO:0016568 187 0.105
viral gene expression GO:0019080 3 0.104
Human
enucleate erythrocyte differentiation GO:0043353 8 0.104
stem cell fate specification GO:0048866 3 0.103
striated muscle tissue development GO:0014706 293 0.103
regulation of response to wounding GO:1903034 189 0.101
regulation of cellular response to stress GO:0080135 159 0.101
regulation of secretion GO:0051046 274 0.101
negative regulation of protein maturation GO:1903318 79 0.100
cell cycle checkpoint GO:0000075 47 0.100
g1 s transition of mitotic cell cycle GO:0000082 57 0.100
amine metabolic process GO:0009308 45 0.100
regulation of mitotic cell cycle phase transition GO:1901990 73 0.099
oocyte axis specification GO:0007309 2 0.098
embryonic limb morphogenesis GO:0030326 126 0.095
Mouse
fat cell differentiation GO:0045444 160 0.094
liver development GO:0001889 66 0.094
somitogenesis GO:0001756 69 0.093
dna integrity checkpoint GO:0031570 28 0.092
granulocyte differentiation GO:0030851 17 0.090
Mouse
regulation of multi organism process GO:0043900 111 0.090
Human
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.089
negative regulation of multi organism process GO:0043901 68 0.089
organelle assembly GO:0070925 177 0.088
mitotic cell cycle process GO:1903047 159 0.088
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.087
negative regulation of cell cycle GO:0045786 123 0.087
response to oxidative stress GO:0006979 123 0.085
canonical wnt signaling pathway GO:0060070 130 0.085
regulation of inflammatory response GO:0050727 147 0.083
protein localization to organelle GO:0033365 185 0.083
regulation of viral transcription GO:0046782 3 0.083
Human
regulation of meiotic cell cycle GO:0051445 34 0.083
regulation of intracellular transport GO:0032386 159 0.082
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.082
oxidation reduction process GO:0055114 342 0.082
response to organonitrogen compound GO:0010243 246 0.081
negative regulation of neuron death GO:1901215 98 0.079
erythrocyte differentiation GO:0030218 88 0.079
embryonic epithelial tube formation GO:0001838 130 0.079
protein deacylation GO:0035601 36 0.079
cellular lipid metabolic process GO:0044255 323 0.078
skin development GO:0043588 220 0.077
blastocyst formation GO:0001825 33 0.077
response to transforming growth factor beta GO:0071559 88 0.076
positive regulation of cell cycle GO:0045787 92 0.074
internal peptidyl lysine acetylation GO:0018393 42 0.074
transdifferentiation GO:0060290 1 0.074
regulation of leukocyte differentiation GO:1902105 159 0.074
regulation of cellular ketone metabolic process GO:0010565 66 0.074
aromatic compound catabolic process GO:0019439 286 0.074
nucleotide metabolic process GO:0009117 332 0.073
regulation of mitotic cell cycle GO:0007346 126 0.072
mitotic cell cycle GO:0000278 195 0.072
positive regulation of proteolysis GO:0045862 85 0.072
cell maturation GO:0048469 127 0.072
connective tissue development GO:0061448 179 0.071
protein modification by small protein conjugation GO:0032446 187 0.070
cellular response to oxidative stress GO:0034599 76 0.070
negative regulation of cell proliferation GO:0008285 296 0.069
bone development GO:0060348 120 0.068
Mouse
syncytium formation by plasma membrane fusion GO:0000768 42 0.068
response to light stimulus GO:0009416 135 0.067
positive regulation of fat cell differentiation GO:0045600 32 0.067
post anal tail morphogenesis GO:0036342 23 0.066
Mouse
peptidyl lysine modification GO:0018205 77 0.065
positive regulation of histone modification GO:0031058 28 0.064
energy derivation by oxidation of organic compounds GO:0015980 77 0.064
epithelial tube formation GO:0072175 130 0.064
heart morphogenesis GO:0003007 178 0.064
neuron migration GO:0001764 122 0.063
positive regulation of cytokine production GO:0001819 174 0.063
ribonucleoprotein complex subunit organization GO:0071826 28 0.062
dna damage checkpoint GO:0000077 26 0.062
hepaticobiliary system development GO:0061008 67 0.060
regulation of peptidyl lysine acetylation GO:2000756 22 0.060
osteoclast differentiation GO:0030316 62 0.060
dendrite development GO:0016358 115 0.059
mitotic cell cycle checkpoint GO:0007093 31 0.059
hair cycle GO:0042633 90 0.059
positive regulation of leukocyte differentiation GO:1902107 86 0.059
erbb signaling pathway GO:0038127 32 0.059
negative regulation of proteolysis GO:0045861 74 0.059
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.059
Human
cellular macromolecule catabolic process GO:0044265 206 0.058
ubiquitin dependent protein catabolic process GO:0006511 129 0.058
negative regulation of gene silencing GO:0060969 2 0.058
response to superoxide GO:0000303 16 0.056
positive regulation of myeloid cell differentiation GO:0045639 43 0.056
viral life cycle GO:0019058 36 0.055
Human
regulation of cell migration GO:0030334 219 0.055
regulation of organ morphogenesis GO:2000027 144 0.055
cardiac muscle cell differentiation GO:0055007 69 0.055
regulation of protein deacetylation GO:0090311 17 0.054
cell cycle g1 s phase transition GO:0044843 57 0.054
regulation of myeloid leukocyte differentiation GO:0002761 58 0.054
rna catabolic process GO:0006401 29 0.054
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 8 0.053
negative regulation of protein processing GO:0010955 79 0.053
regulation of establishment of protein localization GO:0070201 181 0.052
primary neural tube formation GO:0014020 95 0.052
modification dependent protein catabolic process GO:0019941 133 0.052
negative regulation of mitotic cell cycle GO:0045930 58 0.051
definitive hemopoiesis GO:0060216 20 0.050
learning or memory GO:0007611 148 0.050
stem cell development GO:0048864 219 0.050
cytoplasmic mrna processing body assembly GO:0033962 6 0.049
negative regulation of intracellular signal transduction GO:1902532 167 0.049
purine containing compound metabolic process GO:0072521 311 0.048
organic cyclic compound catabolic process GO:1901361 295 0.048
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.047
Human
ear development GO:0043583 200 0.047
regulation of secretion by cell GO:1903530 249 0.047
cardiac muscle tissue development GO:0048738 130 0.047
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.047
meiotic cell cycle GO:0051321 122 0.047
appendage development GO:0048736 166 0.046
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.046
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.046
negative regulation of hormone biosynthetic process GO:0032353 4 0.045
telomere maintenance GO:0000723 19 0.045
viral process GO:0016032 41 0.045
Human
neuroblast differentiation GO:0014016 2 0.045
regulation of ossification GO:0030278 112 0.044
wnt signaling pathway GO:0016055 188 0.044
syncytium formation GO:0006949 43 0.044
negative regulation of nervous system development GO:0051961 156 0.044
negative regulation of molecular function GO:0044092 258 0.044
actin filament based movement GO:0030048 23 0.044
negative regulation of cell cycle process GO:0010948 69 0.044
mesenchyme development GO:0060485 152 0.044
protein maturation GO:0051604 176 0.043
regulation of cellular protein catabolic process GO:1903362 61 0.043
cellular response to steroid hormone stimulus GO:0071383 33 0.043
purine ribonucleoside catabolic process GO:0046130 205 0.043
regulation of organ growth GO:0046620 61 0.043
regulation of hormone levels GO:0010817 211 0.043
cell type specific apoptotic process GO:0097285 268 0.043
myelination in peripheral nervous system GO:0022011 19 0.043
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 3 0.043
regulation of cellular component biogenesis GO:0044087 181 0.042
regulation of striated muscle cell differentiation GO:0051153 81 0.042
negative regulation of lipid metabolic process GO:0045833 30 0.042
inflammatory response GO:0006954 244 0.042
histone lysine demethylation GO:0070076 13 0.042
interspecies interaction between organisms GO:0044419 83 0.042
Human
regulation of membrane potential GO:0042391 192 0.042
chemotaxis GO:0006935 247 0.041
response to osmotic stress GO:0006970 21 0.041
regulation of cysteine type endopeptidase activity GO:2000116 65 0.041
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.041
axon guidance GO:0007411 141 0.041
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.041
nucleocytoplasmic transport GO:0006913 139 0.041
gene silencing by mirna GO:0035195 10 0.040
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.040
response to epidermal growth factor GO:0070849 4 0.040
negative regulation of alcohol biosynthetic process GO:1902931 4 0.040
kidney development GO:0001822 213 0.040
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.040
negative regulation of phosphorus metabolic process GO:0010563 184 0.039
intracellular mrna localization GO:0008298 4 0.039
tube closure GO:0060606 91 0.039
microtubule cytoskeleton organization GO:0000226 157 0.039
ion transmembrane transport GO:0034220 361 0.039
small molecule biosynthetic process GO:0044283 132 0.039
modification of morphology or physiology of other organism GO:0035821 18 0.039
Human
regulation of chromatin organization GO:1902275 57 0.039
compound eye development GO:0048749 1 0.038
regulation of body fluid levels GO:0050878 162 0.038
negative regulation of phosphorylation GO:0042326 166 0.038
production of molecular mediator of immune response GO:0002440 103 0.038
negative regulation of inflammatory response GO:0050728 61 0.038
skeletal muscle organ development GO:0060538 163 0.038
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.038
regulation of peptidase activity GO:0052547 96 0.038
neural tube formation GO:0001841 108 0.038
oogenesis GO:0048477 56 0.037
cellular response to lipid GO:0071396 145 0.037
immune effector process GO:0002252 321 0.037
regulation of epithelial cell proliferation GO:0050678 141 0.037
nucleoside phosphate catabolic process GO:1901292 222 0.037
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.037
Human
single organism cell adhesion GO:0098602 156 0.037
embryonic camera type eye development GO:0031076 36 0.037
cellular response to hormone stimulus GO:0032870 150 0.037
cellular protein catabolic process GO:0044257 155 0.037
mesenchymal cell differentiation GO:0048762 107 0.037
meiosis i GO:0007127 60 0.036
endocrine system development GO:0035270 98 0.036
posttranscriptional gene silencing by rna GO:0035194 10 0.036
myotube differentiation GO:0014902 105 0.036
male meiosis i GO:0007141 16 0.036
regulation of nuclear cell cycle dna replication GO:0033262 2 0.036
negative regulation of defense response GO:0031348 77 0.035
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.035
regulation of histone deacetylation GO:0031063 12 0.035
regulation of endopeptidase activity GO:0052548 89 0.035
nephron development GO:0072006 109 0.035
positive regulation of histone h3 k9 methylation GO:0051574 4 0.035
organ growth GO:0035265 117 0.035
regulation of proteolysis GO:0030162 164 0.035
purine ribonucleotide catabolic process GO:0009154 208 0.035
respiratory tube development GO:0030323 167 0.034
regulation of histone h3 k9 methylation GO:0051570 8 0.034
regulation of protein catabolic process GO:0042176 108 0.034
neuronal action potential GO:0019228 54 0.034
cognition GO:0050890 149 0.034
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.034
heart process GO:0003015 94 0.034
Mouse
gene silencing by rna GO:0031047 19 0.034
nuclear transport GO:0051169 139 0.034
dna dependent dna replication GO:0006261 24 0.034
oocyte construction GO:0007308 2 0.033
regulation of transcription by chromatin organization GO:0034401 0 0.033
response to purine containing compound GO:0014074 28 0.033
organonitrogen compound catabolic process GO:1901565 264 0.033
bone mineralization GO:0030282 54 0.033
rna localization GO:0006403 23 0.033
maintenance of chromatin silencing GO:0006344 2 0.033
negative regulation of fat cell differentiation GO:0045599 36 0.033
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.033
positive regulation of osteoclast differentiation GO:0045672 15 0.033
histone lysine methylation GO:0034968 50 0.033
meiotic nuclear division GO:0007126 115 0.033
intracellular protein transport GO:0006886 204 0.032
cytoplasmic transport GO:0016482 234 0.032
rna processing GO:0006396 105 0.032
angiogenesis GO:0001525 201 0.032
morphogenesis of embryonic epithelium GO:0016331 159 0.032
histone demethylation GO:0016577 13 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
cardiac muscle cell contraction GO:0086003 7 0.031
tube formation GO:0035148 140 0.031
immunoglobulin mediated immune response GO:0016064 69 0.031
alcohol metabolic process GO:0006066 116 0.031
ribonucleotide metabolic process GO:0009259 291 0.030
ras protein signal transduction GO:0007265 77 0.030
cellular response to inorganic substance GO:0071241 37 0.030
regulation of protein localization GO:0032880 231 0.030
regulation of chromatin modification GO:1903308 57 0.030
multicellular organismal signaling GO:0035637 91 0.030
negative regulation of organelle organization GO:0010639 90 0.030
actin mediated cell contraction GO:0070252 15 0.030
positive regulation of chromosome organization GO:2001252 33 0.029
leukocyte activation involved in immune response GO:0002366 126 0.029
tissue migration GO:0090130 68 0.029
negative regulation of response to wounding GO:1903035 77 0.029
cardiac chamber morphogenesis GO:0003206 93 0.029
negative regulation of phosphate metabolic process GO:0045936 184 0.029
neuron death GO:0070997 154 0.029
limb development GO:0060173 166 0.029
Mouse
cellular response to epidermal growth factor stimulus GO:0071364 4 0.028
forebrain development GO:0030900 302 0.028
mrna transcription GO:0009299 4 0.028
actin cytoskeleton organization GO:0030036 220 0.028
regulation of mrna stability GO:0043488 23 0.028
histone h3 k9 dimethylation GO:0036123 4 0.028
response to peptide GO:1901652 136 0.028
negative regulation of transcription from rna polymerase i promoter GO:0016479 2 0.028
inorganic ion transmembrane transport GO:0098660 234 0.028
positive regulation of growth GO:0045927 104 0.028
cellular response to organic cyclic compound GO:0071407 87 0.028
sensory perception of sound GO:0007605 97 0.028
cellular response to gamma radiation GO:0071480 4 0.028
negative regulation of viral transcription GO:0032897 3 0.028
purine nucleoside triphosphate catabolic process GO:0009146 203 0.028
positive regulation of cellular component biogenesis GO:0044089 94 0.028
negative regulation of hormone metabolic process GO:0032351 4 0.028
regulation of translation GO:0006417 71 0.028
cytokine production GO:0001816 319 0.028
cation transmembrane transport GO:0098655 266 0.027
regulation of osteoclast differentiation GO:0045670 36 0.027
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 3 0.027
mrna metabolic process GO:0016071 84 0.027
peptidyl lysine acetylation GO:0018394 45 0.027
rna 3 end processing GO:0031123 20 0.027
axonogenesis GO:0007409 274 0.027
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 4 0.027
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.027
regulation of dna templated transcription in response to stress GO:0043620 9 0.027
regulation of protein transport GO:0051223 163 0.027
negative regulation of secretion GO:0051048 61 0.027
epithelial cell migration GO:0010631 63 0.026
spermatid development GO:0007286 108 0.026
regulation of transcription from rna polymerase i promoter GO:0006356 6 0.026
female gonad development GO:0008585 71 0.026
myoblast differentiation GO:0045445 52 0.026
somatotropin secreting cell development GO:0060133 2 0.026
spongiotrophoblast layer development GO:0060712 15 0.026
negative regulation of kinase activity GO:0033673 81 0.026
nephron epithelium development GO:0072009 92 0.026
positive regulation of organelle organization GO:0010638 128 0.026
ectodermal cell differentiation GO:0010668 3 0.026
molting cycle GO:0042303 90 0.025
regulation of gene silencing GO:0060968 7 0.025
Fly
regulation of muscle tissue development GO:1901861 97 0.025
regulation of autophagy GO:0010506 30 0.025
proteasomal protein catabolic process GO:0010498 98 0.025
epithelial cell development GO:0002064 159 0.025
regulation of circadian rhythm GO:0042752 58 0.025
response to uv GO:0009411 44 0.025
cation transport GO:0006812 399 0.025
appendage morphogenesis GO:0035107 149 0.025
Mouse
macromolecule deacylation GO:0098732 37 0.025
purine containing compound catabolic process GO:0072523 213 0.025
monocarboxylic acid metabolic process GO:0032787 191 0.025
multicellular organismal aging GO:0010259 24 0.025
regulation of cell activation GO:0050865 289 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
regulation of hydrolase activity GO:0051336 246 0.024
retina development in camera type eye GO:0060041 119 0.024
skeletal system morphogenesis GO:0048705 203 0.024
Mouse
stress activated mapk cascade GO:0051403 80 0.024
purine nucleoside triphosphate metabolic process GO:0009144 226 0.024
nucleoside metabolic process GO:0009116 246 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.024
regulation of ketone biosynthetic process GO:0010566 2 0.024
positive regulation of protein modification process GO:0031401 299 0.024
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.023
lung cell differentiation GO:0060479 30 0.023
signal transduction involved in dna damage checkpoint GO:0072422 3 0.023
pituitary gland development GO:0021983 38 0.023
regulation of mrna processing GO:0050684 41 0.023
negative regulation of protein phosphorylation GO:0001933 126 0.023
nerve development GO:0021675 67 0.023
positive regulation of epithelial cell proliferation GO:0050679 68 0.023
regulation of jnk cascade GO:0046328 62 0.023
epidermis development GO:0008544 187 0.023
positive regulation of peptidase activity GO:0010952 49 0.023
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.022
protein import GO:0017038 101 0.022
adipose tissue development GO:0060612 25 0.022
stem cell maintenance GO:0019827 130 0.022
regulation of lipid biosynthetic process GO:0046890 54 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
aortic valve morphogenesis GO:0003180 4 0.022
negative regulation of dna replication GO:0008156 4 0.022
nitrogen compound transport GO:0071705 271 0.022
lymphocyte anergy GO:0002249 4 0.022
neutral lipid metabolic process GO:0006638 57 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.022
regulation of stem cell differentiation GO:2000736 50 0.022
positive chemotaxis GO:0050918 18 0.022
heart valve development GO:0003170 23 0.022
neuroepithelial cell differentiation GO:0060563 37 0.022
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.022
protein methylation GO:0006479 81 0.022
steroid metabolic process GO:0008202 119 0.022
smoothened signaling pathway GO:0007224 105 0.021
negative regulation of leukocyte proliferation GO:0070664 46 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
cellular potassium ion transport GO:0071804 43 0.021
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.021
regulation of mapk cascade GO:0043408 248 0.021
epithelial cell morphogenesis GO:0003382 41 0.021
cardiac muscle contraction GO:0060048 32 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
neural tube closure GO:0001843 90 0.021
anatomical structure homeostasis GO:0060249 145 0.021
response to oxygen levels GO:0070482 62 0.021
positive regulation of ossification GO:0045778 47 0.021
meiotic cell cycle process GO:1903046 77 0.021
histone h4 acetylation GO:0043967 10 0.021
protein dealkylation GO:0008214 13 0.020
regulation of cell motility GO:2000145 236 0.020
negative regulation of exocytosis GO:0045920 12 0.020
regulation of antimicrobial humoral response GO:0002759 3 0.020

Sp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
thoracic cancer DOID:5093 0 0.043
cancer DOID:162 0 0.043
disease of cellular proliferation DOID:14566 0 0.043
organ system cancer DOID:0050686 0 0.043