Mus musculus

28 known processes

Sp6

trans-acting transcription factor 6

(Aliases: 1110025J03Rik,Epfn,AI592962,Klf14,AA591031)

Sp6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
odontogenesis GO:0042476 78 0.550
odontogenesis of dentin containing tooth GO:0042475 66 0.392
skin development GO:0043588 220 0.378
cell adhesion GO:0007155 329 0.347
sensory perception GO:0007600 245 0.321
epidermis development GO:0008544 187 0.311
cellular amino acid metabolic process GO:0006520 103 0.253
forebrain development GO:0030900 302 0.206
calcium ion transport GO:0006816 159 0.199
regulation of cell cycle GO:0051726 281 0.198
inorganic ion transmembrane transport GO:0098660 234 0.197
regionalization GO:0003002 337 0.192
cellular ketone metabolic process GO:0042180 84 0.189
cation transmembrane transport GO:0098655 266 0.177
anion transport GO:0006820 177 0.161
ion transmembrane transport GO:0034220 361 0.155
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.145
negative regulation of cellular amine metabolic process GO:0033239 1 0.137
regulation of cell cycle process GO:0010564 160 0.135
regulation of cellular ketone metabolic process GO:0010565 66 0.134
regulation of cellular amino acid metabolic process GO:0006521 5 0.133
regulation of cellular amine metabolic process GO:0033238 20 0.128
gland development GO:0048732 330 0.127
camera type eye development GO:0043010 266 0.124
divalent metal ion transport GO:0070838 172 0.121
negative regulation of protein metabolic process GO:0051248 282 0.121
morphogenesis of an epithelial fold GO:0060571 28 0.120
hair follicle development GO:0001942 85 0.119
cation transport GO:0006812 399 0.118
epidermis morphogenesis GO:0048730 33 0.115
inner ear receptor cell differentiation GO:0060113 61 0.113
actin cytoskeleton organization GO:0030036 220 0.110
positive regulation of cell cycle GO:0045787 92 0.109
sensory perception of mechanical stimulus GO:0050954 107 0.109
leukocyte differentiation GO:0002521 342 0.106
Mouse
locomotory behavior GO:0007626 195 0.105
compound eye development GO:0048749 1 0.105
wnt signaling pathway GO:0016055 188 0.104
cellular amine metabolic process GO:0044106 44 0.104
inorganic cation transmembrane transport GO:0098662 207 0.103
negative regulation of striated muscle cell differentiation GO:0051154 14 0.102
lateral inhibition GO:0046331 1 0.100
regulation of organelle organization GO:0033043 289 0.099
cardiac chamber development GO:0003205 108 0.095
skeletal system development GO:0001501 356 0.095
cardiac ventricle development GO:0003231 83 0.093
amine metabolic process GO:0009308 45 0.089
bmp signaling pathway GO:0030509 93 0.087
epithelial tube morphogenesis GO:0060562 303 0.084
trachea gland development GO:0061153 3 0.083
transmembrane transport GO:0055085 412 0.081
central nervous system neuron differentiation GO:0021953 162 0.080
polarity specification of proximal distal axis GO:0010085 2 0.080
synaptic transmission GO:0007268 329 0.079
divalent inorganic cation transport GO:0072511 178 0.078
ribonucleoside metabolic process GO:0009119 245 0.078
regulation of keratinocyte differentiation GO:0045616 11 0.078
hair follicle morphogenesis GO:0031069 29 0.077
tissue remodeling GO:0048771 102 0.075
skin morphogenesis GO:0043589 38 0.075
epithelial cell development GO:0002064 159 0.074
regulation of epidermis development GO:0045682 33 0.071
cell fate commitment GO:0045165 210 0.070
limb development GO:0060173 166 0.069
embryonic organ morphogenesis GO:0048562 276 0.069
neuron projection guidance GO:0097485 141 0.069
positive regulation of organelle organization GO:0010638 128 0.068
regulation of canonical wnt signaling pathway GO:0060828 82 0.066
activation of meiosis GO:0090427 4 0.066
cell fate determination involved in pattern specification GO:0060582 1 0.065
stem cell development GO:0048864 219 0.065
Mouse
trachea submucosa development GO:0061152 3 0.065
developmental maturation GO:0021700 193 0.062
lung development GO:0030324 164 0.061
wound healing GO:0042060 157 0.060
organelle fission GO:0048285 170 0.060
respiratory system development GO:0060541 190 0.060
cellular homeostasis GO:0019725 240 0.059
regulation of membrane potential GO:0042391 192 0.058
neuroblast differentiation GO:0014016 2 0.057
negative regulation of keratinocyte differentiation GO:0045617 4 0.057
determination of left right symmetry GO:0007368 80 0.057
heart trabecula morphogenesis GO:0061384 26 0.056
tooth mineralization GO:0034505 9 0.056
stem cell differentiation GO:0048863 268 0.056
Mouse
negative regulation of notch signaling pathway GO:0045746 14 0.054
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.054
mesenchymal cell development GO:0014031 93 0.054
muscle cell differentiation GO:0042692 261 0.054
exocrine system development GO:0035272 45 0.053
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.053
endomembrane system organization GO:0010256 147 0.053
hair cycle GO:0042633 90 0.053
negative regulation of cell proliferation GO:0008285 296 0.053
nitrogen compound transport GO:0071705 271 0.053
placenta development GO:0001890 140 0.052
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
female gamete generation GO:0007292 74 0.050
Worm
negative regulation of cellular component organization GO:0051129 194 0.050
response to growth factor GO:0070848 198 0.050
hair cycle phase GO:0044851 16 0.049
endodermal cell fate specification GO:0001714 4 0.048
regulation of mitotic cell cycle GO:0007346 126 0.047
cellular metal ion homeostasis GO:0006875 151 0.047
striated muscle tissue development GO:0014706 293 0.046
positive regulation of neuron projection development GO:0010976 79 0.046
neuroblast fate determination GO:0007400 1 0.046
meiotic cell cycle GO:0051321 122 0.046
trabecula morphogenesis GO:0061383 40 0.045
positive regulation of meiotic cell cycle GO:0051446 15 0.045
molting cycle GO:0042303 90 0.044
positive regulation of growth GO:0045927 104 0.044
respiratory tube development GO:0030323 167 0.044
regulation of nuclear division GO:0051783 56 0.043
nucleoside triphosphate metabolic process GO:0009141 230 0.043
negative regulation of fat cell differentiation GO:0045599 36 0.043
organic anion transport GO:0015711 137 0.043
regulation of ion transmembrane transport GO:0034765 119 0.042
histone modification GO:0016570 159 0.042
axonogenesis GO:0007409 274 0.042
sensory organ morphogenesis GO:0090596 242 0.042
regulation of cell motility GO:2000145 236 0.042
skeletal muscle cell differentiation GO:0035914 66 0.041
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.041
intracellular protein transport GO:0006886 204 0.041
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.040
regulation of organ formation GO:0003156 34 0.040
mitotic cell cycle GO:0000278 195 0.040
peptidyl amino acid modification GO:0018193 336 0.040
stem cell fate determination GO:0048867 2 0.040
appendage development GO:0048736 166 0.040
oogenesis GO:0048477 56 0.040
Worm
regulation of cell division GO:0051302 76 0.039
negative regulation of cellular protein metabolic process GO:0032269 247 0.039
organic acid biosynthetic process GO:0016053 86 0.038
skeletal muscle fiber development GO:0048741 58 0.038
cell type specific apoptotic process GO:0097285 268 0.038
positive regulation of programmed cell death GO:0043068 218 0.038
Worm
ras protein signal transduction GO:0007265 77 0.038
regulation of cellular response to growth factor stimulus GO:0090287 82 0.037
positive regulation of nervous system development GO:0051962 221 0.037
regulation of reproductive process GO:2000241 66 0.037
regulation of wnt signaling pathway GO:0030111 123 0.037
cytokine production GO:0001816 319 0.037
calcium ion transmembrane transport GO:0070588 85 0.037
epithelial to mesenchymal transition GO:0001837 47 0.037
organonitrogen compound catabolic process GO:1901565 264 0.036
peptide transport GO:0015833 133 0.036
ear development GO:0043583 200 0.036
regulation of neuron differentiation GO:0045664 281 0.036
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.035
regulation of endodermal cell fate specification GO:0042663 2 0.035
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.035
engulfment of apoptotic cell GO:0043652 3 0.035
regulation of organ growth GO:0046620 61 0.035
regulation of striated muscle cell differentiation GO:0051153 81 0.035
morphogenesis of an endothelium GO:0003159 2 0.034
small gtpase mediated signal transduction GO:0007264 97 0.034
nerve development GO:0021675 67 0.034
germ cell development GO:0007281 185 0.034
Worm
salivary gland morphogenesis GO:0007435 33 0.034
regulation of muscle tissue development GO:1901861 97 0.034
positive regulation of hydrolase activity GO:0051345 148 0.034
inflammatory response GO:0006954 244 0.033
mitotic cell cycle process GO:1903047 159 0.033
hair cell differentiation GO:0035315 40 0.033
blood vessel remodeling GO:0001974 33 0.033
negative regulation of cell cycle GO:0045786 123 0.033
positive regulation of apoptotic process GO:0043065 217 0.033
Worm
epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198 10 0.032
i kappab kinase nf kappab signaling GO:0007249 85 0.032
regulation of retina development in camera type eye GO:1902866 3 0.032
stem cell maintenance GO:0019827 130 0.032
Mouse
adult behavior GO:0030534 135 0.031
primary neural tube formation GO:0014020 95 0.031
midgut development GO:0007494 4 0.031
aromatic compound catabolic process GO:0019439 286 0.031
negative regulation of epidermis development GO:0045683 9 0.031
posttranscriptional regulation of gene expression GO:0010608 155 0.031
regulation of neural retina development GO:0061074 3 0.031
mesonephros development GO:0001823 97 0.030
negative regulation of protein modification process GO:0031400 163 0.030
muscle cell proliferation GO:0033002 52 0.030
regulation of meiotic cell cycle GO:0051445 34 0.030
nucleocytoplasmic transport GO:0006913 139 0.030
embryonic epithelial tube formation GO:0001838 130 0.030
cell division GO:0051301 120 0.030
lens morphogenesis in camera type eye GO:0002089 24 0.030
muscle system process GO:0003012 141 0.030
regulation of auditory receptor cell differentiation GO:0045607 4 0.030
tube formation GO:0035148 140 0.030
regulation of protein import into nucleus GO:0042306 52 0.030
left right pattern formation GO:0060972 23 0.030
pancreatic a cell fate commitment GO:0003326 2 0.029
metal ion homeostasis GO:0055065 189 0.029
canonical wnt signaling pathway GO:0060070 130 0.029
mesenchymal cell differentiation involved in lung development GO:0060915 2 0.029
negative regulation of protein phosphorylation GO:0001933 126 0.029
sensory perception of light stimulus GO:0050953 54 0.028
cytoplasmic transport GO:0016482 234 0.028
maintenance of location GO:0051235 89 0.028
nucleoside triphosphate catabolic process GO:0009143 205 0.028
monocarboxylic acid metabolic process GO:0032787 191 0.028
lymphocyte differentiation GO:0030098 242 0.028
notch signaling pathway GO:0007219 71 0.028
negative regulation of molecular function GO:0044092 258 0.028
ameboidal type cell migration GO:0001667 128 0.028
glycosyl compound metabolic process GO:1901657 246 0.028
cellular chemical homeostasis GO:0055082 215 0.027
regulation of binding GO:0051098 111 0.027
nuclear import GO:0051170 95 0.027
regulation of cardioblast differentiation GO:0051890 3 0.027
digestive system development GO:0055123 200 0.027
keratinocyte differentiation GO:0030216 48 0.027
dendrite development GO:0016358 115 0.027
regulation of cardiac muscle tissue growth GO:0055021 26 0.027
auditory receptor cell differentiation GO:0042491 37 0.027
mammary gland epithelium development GO:0061180 65 0.027
microtubule cytoskeleton organization GO:0000226 157 0.027
regulation of protein targeting GO:1903533 61 0.027
negative regulation of epidermal cell differentiation GO:0045605 7 0.026
telencephalon development GO:0021537 186 0.026
bronchiole development GO:0060435 3 0.026
chondrocyte differentiation GO:0002062 72 0.026
organelle assembly GO:0070925 177 0.026
spermatogenesis GO:0007283 284 0.026
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.026
positive regulation of anagen GO:0051885 1 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
cellular response to lipid GO:0071396 145 0.025
nucleoside metabolic process GO:0009116 246 0.025
regulation of cell projection organization GO:0031344 206 0.025
cartilage development GO:0051216 140 0.025
positive regulation of meiosis GO:0045836 14 0.025
visual perception GO:0007601 52 0.025
formation of organ boundary GO:0010160 1 0.025
cell maturation GO:0048469 127 0.025
regulation of myeloid cell differentiation GO:0045637 96 0.025
Mouse
regulation of homeostatic process GO:0032844 182 0.025
cell cell signaling involved in cell fate commitment GO:0045168 35 0.024
biological phase GO:0044848 20 0.024
cytokine mediated signaling pathway GO:0019221 115 0.024
negative regulation of nervous system development GO:0051961 156 0.024
leukocyte activation involved in immune response GO:0002366 126 0.024
meiotic nuclear division GO:0007126 115 0.024
regulation of notch signaling pathway GO:0008593 35 0.024
nucleoside phosphate metabolic process GO:0006753 338 0.024
cellular response to hormone stimulus GO:0032870 150 0.023
positive regulation of cellular catabolic process GO:0031331 148 0.023
protein localization to plasma membrane GO:0072659 57 0.023
anion transmembrane transport GO:0098656 71 0.023
limb morphogenesis GO:0035108 149 0.023
positive regulation of cell development GO:0010720 237 0.023
heart morphogenesis GO:0003007 178 0.023
carbohydrate metabolic process GO:0005975 230 0.023
positive regulation of cell cycle process GO:0090068 61 0.023
regulation of stem cell differentiation GO:2000736 50 0.023
multicellular organism growth GO:0035264 161 0.023
protein import GO:0017038 101 0.023
neural tube development GO:0021915 160 0.023
sensory system development GO:0048880 3 0.023
peptidyl lysine modification GO:0018205 77 0.023
apoptotic signaling pathway GO:0097190 306 0.023
positive regulation of cell death GO:0010942 224 0.023
Worm
regulation of ion transmembrane transporter activity GO:0032412 54 0.023
muscle tissue development GO:0060537 308 0.023
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.022
glial cell differentiation GO:0010001 131 0.022
carbohydrate homeostasis GO:0033500 128 0.022
wound healing spreading of cells GO:0044319 8 0.022
protein targeting GO:0006605 143 0.022
membrane organization GO:0061024 245 0.022
trabecula formation GO:0060343 24 0.022
compartment pattern specification GO:0007386 4 0.022
regulation of transmembrane transport GO:0034762 128 0.022
diencephalon development GO:0021536 63 0.021
regulation of secretion GO:0051046 274 0.021
axon guidance GO:0007411 141 0.021
developmental growth involved in morphogenesis GO:0060560 138 0.021
cellular ion homeostasis GO:0006873 165 0.021
morphogenesis of a branching epithelium GO:0061138 193 0.021
guanosine containing compound metabolic process GO:1901068 144 0.021
neural tube formation GO:0001841 108 0.021
regulation of cytoskeleton organization GO:0051493 122 0.021
ribose phosphate metabolic process GO:0019693 291 0.021
nuclear division GO:0000280 158 0.021
negative regulation of wnt signaling pathway GO:0030178 73 0.021
regulation of establishment of protein localization GO:0070201 181 0.021
protein import into nucleus GO:0006606 95 0.021
striated muscle cell proliferation GO:0014855 39 0.021
positive regulation of hair cycle GO:0042635 7 0.021
sensory organ boundary specification GO:0008052 1 0.020
endothelial tube morphogenesis GO:0061154 2 0.020
mesenchymal cell differentiation GO:0048762 107 0.020
regulation of ion transport GO:0043269 215 0.020
inner ear morphogenesis GO:0042472 101 0.020
apoptotic process involved in development GO:1902742 28 0.020
protein localization to nucleus GO:0034504 121 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
pancreas development GO:0031016 57 0.020
regulation of mitotic cell cycle phase transition GO:1901990 73 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
chromatin modification GO:0016568 187 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
neuroblast fate commitment GO:0014017 1 0.020
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.020
endocardial cushion development GO:0003197 26 0.019
synapse organization GO:0050808 125 0.019
cell activation involved in immune response GO:0002263 126 0.019
chromatin organization GO:0006325 206 0.019
atrioventricular node development GO:0003162 3 0.019
somite specification GO:0001757 4 0.019
negative regulation of cell development GO:0010721 169 0.019
regulation of chromosome organization GO:0033044 83 0.019
developmental induction GO:0031128 34 0.019
cranial nerve development GO:0021545 41 0.019
negative regulation of organelle organization GO:0010639 90 0.019
regulation of t cell activation GO:0050863 170 0.019
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.019
enamel mineralization GO:0070166 7 0.019
actin filament organization GO:0007015 113 0.019
mesoderm development GO:0007498 100 0.019
nuclear transport GO:0051169 139 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
adult locomotory behavior GO:0008344 91 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
positive regulation of striated muscle tissue development GO:0045844 31 0.018
detection of external stimulus GO:0009581 61 0.018
midbrain hindbrain boundary maturation GO:0021732 1 0.018
regulation of feeding behavior GO:0060259 3 0.018
response to organic cyclic compound GO:0014070 198 0.018
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.018
striated muscle cell development GO:0055002 125 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
response to organonitrogen compound GO:0010243 246 0.018
cardiac chamber morphogenesis GO:0003206 93 0.018
regulation of neuron projection development GO:0010975 169 0.018
determination of heart left right asymmetry GO:0061371 48 0.018
detection of abiotic stimulus GO:0009582 60 0.018
nucleobase containing small molecule metabolic process GO:0055086 352 0.018
embryonic heart tube morphogenesis GO:0003143 51 0.018
osteoclast differentiation GO:0030316 62 0.018
Mouse
central nervous system vasculogenesis GO:0022009 3 0.018
cardiocyte differentiation GO:0035051 87 0.018
negative regulation of mitotic cell cycle GO:0045930 58 0.017
development of primary sexual characteristics GO:0045137 143 0.017
Worm
detection of stimulus GO:0051606 84 0.017
positive regulation of nuclear division GO:0051785 27 0.017
regulation of transferase activity GO:0051338 263 0.017
protein acylation GO:0043543 64 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.017
outflow tract morphogenesis GO:0003151 53 0.017
branching morphogenesis of an epithelial tube GO:0048754 159 0.017
negative regulation of auditory receptor cell differentiation GO:0045608 2 0.017
kidney development GO:0001822 213 0.017
genitalia development GO:0048806 37 0.017
Worm
regulation of osteoblast differentiation GO:0045667 67 0.017
embryonic limb morphogenesis GO:0030326 126 0.017
cardiac muscle tissue development GO:0048738 130 0.017
regulation of cardiac muscle tissue development GO:0055024 31 0.017
positive regulation of nucleoside metabolic process GO:0045979 91 0.017
amelogenesis GO:0097186 12 0.017
cardiac muscle cell differentiation GO:0055007 69 0.017
regulation of asymmetric cell division GO:0009786 4 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.017
positive regulation of mesenchymal cell apoptotic process GO:2001055 3 0.017
regulation of neuron apoptotic process GO:0043523 122 0.017
nucleotide catabolic process GO:0009166 217 0.017
inner ear receptor cell development GO:0060119 39 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.017
single fertilization GO:0007338 82 0.016
endocrine system development GO:0035270 98 0.016
cell cycle switching GO:0060184 1 0.016
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.016
mesoderm morphogenesis GO:0048332 64 0.016
positive regulation of osteoblast differentiation GO:0045669 34 0.016
regulation of cell growth GO:0001558 91 0.016
positive regulation of muscle tissue development GO:1901863 32 0.016
morphogenesis of an epithelial sheet GO:0002011 27 0.016
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.016
cell cell adhesion GO:0098609 41 0.016
ventricular trabecula myocardium morphogenesis GO:0003222 11 0.016
homeostasis of number of cells GO:0048872 210 0.016
embryonic heart tube development GO:0035050 65 0.016
covalent chromatin modification GO:0016569 163 0.016
apoptotic process involved in morphogenesis GO:0060561 25 0.016
peptidyl serine phosphorylation GO:0018105 74 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
cardiac right ventricle formation GO:0003219 3 0.016
renal system development GO:0072001 225 0.016
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.016
plasma membrane organization GO:0007009 90 0.016
regulation of hair follicle development GO:0051797 9 0.016
neuron apoptotic process GO:0051402 142 0.016
germ line stem cell division GO:0042078 2 0.016
positive regulation of secretion GO:0051047 130 0.016
peptide hormone secretion GO:0030072 109 0.016
regulation of endothelial cell migration GO:0010594 22 0.016
positive regulation of keratinocyte differentiation GO:0045618 3 0.016
sensory perception of sound GO:0007605 97 0.016
appendage morphogenesis GO:0035107 149 0.016
epithelium migration GO:0090132 63 0.016
somitogenesis GO:0001756 69 0.016
positive regulation of transcription via serum response element binding GO:0010735 1 0.015
nucleotide metabolic process GO:0009117 332 0.015
chemotaxis GO:0006935 247 0.015
carboxylic acid transport GO:0046942 100 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
glucose homeostasis GO:0042593 128 0.015
embryonic skeletal system morphogenesis GO:0048704 91 0.015
positive regulation of ion transport GO:0043270 65 0.015
tissue regeneration GO:0042246 22 0.015
nail development GO:0035878 5 0.015
digestive tract development GO:0048565 190 0.015
regulation of protein binding GO:0043393 60 0.015
gtp metabolic process GO:0046039 144 0.015
lung cell differentiation GO:0060479 30 0.015
ear morphogenesis GO:0042471 118 0.015
middle ear morphogenesis GO:0042474 23 0.015
calcium ion dependent exocytosis GO:0017156 35 0.015
positive regulation of epithelial cell proliferation GO:0050679 68 0.015
salivary gland development GO:0007431 37 0.015
regulation of rho protein signal transduction GO:0035023 71 0.015
negative regulation of creb transcription factor activity GO:0032792 2 0.015
cell recognition GO:0008037 83 0.015
sequestering of metal ion GO:0051238 19 0.015
cardiac right atrium morphogenesis GO:0003213 3 0.015
regulation of intracellular protein transport GO:0033157 82 0.015
positive regulation of transmembrane transport GO:0034764 29 0.015
negative regulation of cell cycle process GO:0010948 69 0.015
tube lumen cavitation GO:0060605 5 0.015
regulation of bmp signaling pathway GO:0030510 60 0.015
monosaccharide metabolic process GO:0005996 106 0.015
pancreatic pp cell differentiation GO:0003312 2 0.015
regulation of hormone levels GO:0010817 211 0.014
positive regulation of cellular component biogenesis GO:0044089 94 0.014
regulation of cardiac muscle cell proliferation GO:0060043 23 0.014
organic acid transport GO:0015849 101 0.014
negative regulation of kinase activity GO:0033673 81 0.014
positive regulation of protein import into nucleus GO:0042307 26 0.014
rna processing GO:0006396 105 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
epithelial tube formation GO:0072175 130 0.014
exocytosis GO:0006887 121 0.014
embryonic appendage morphogenesis GO:0035113 126 0.014
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.014
respiratory system process GO:0003016 25 0.014
anatomical structure maturation GO:0071695 49 0.014
response to extracellular stimulus GO:0009991 127 0.014
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 65 0.014
intermediate filament cytoskeleton organization GO:0045104 26 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
positive regulation of protein localization to nucleus GO:1900182 30 0.014
mitochondrial transport GO:0006839 36 0.014
positive regulation of protein modification process GO:0031401 299 0.014
regulation of endodermal cell differentiation GO:1903224 2 0.014
positive regulation of cell division GO:0051781 31 0.014
cell proliferation in forebrain GO:0021846 30 0.014
spermatid differentiation GO:0048515 115 0.014
peptide secretion GO:0002790 114 0.014
regulation of epithelial cell migration GO:0010632 35 0.014
blood vessel lumenization GO:0072554 2 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
regulation of mapk cascade GO:0043408 248 0.014
chloride transmembrane transport GO:1902476 24 0.014
negative regulation of neuron differentiation GO:0045665 101 0.014
cardiac muscle tissue morphogenesis GO:0055008 44 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
negative regulation of cell fate specification GO:0009996 4 0.014
negative regulation of mechanoreceptor differentiation GO:0045632 3 0.014
biomineral tissue development GO:0031214 64 0.014
Mouse
cellular response to extracellular stimulus GO:0031668 81 0.014
Mouse
regulation of endocytosis GO:0030100 69 0.014
monocarboxylic acid transport GO:0015718 44 0.014
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
signal transduction by p53 class mediator GO:0072331 51 0.014
heterocycle catabolic process GO:0046700 280 0.014
extracellular structure organization GO:0043062 148 0.014
regulation of cell activation GO:0050865 289 0.014
regulation of body fluid levels GO:0050878 162 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.014
embryonic skeletal system development GO:0048706 120 0.014
negative regulation of cell projection organization GO:0031345 56 0.013
cell migration involved in endocardial cushion formation GO:0003273 3 0.013
regulation of peptide transport GO:0090087 91 0.013
limbic system development GO:0021761 72 0.013

Sp6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
musculoskeletal system disease DOID:17 0 0.032
connective tissue disease DOID:65 0 0.032
mouth disease DOID:403 0 0.029
gastrointestinal system disease DOID:77 0 0.029
bone disease DOID:0080001 0 0.026
bone development disease DOID:0080006 0 0.016