Mus musculus

38 known processes

Sphk1

sphingosine kinase 1

(Aliases: Sk1,1110006G24Rik,Spk1)

Sphk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cytokine production GO:0001817 266 0.413
amine metabolic process GO:0009308 45 0.401
nitrogen compound transport GO:0071705 271 0.375
Human Worm
renal system development GO:0072001 225 0.322
striated muscle tissue development GO:0014706 293 0.293
blood vessel morphogenesis GO:0048514 285 0.292
Human
cellular amino acid metabolic process GO:0006520 103 0.250
muscle tissue development GO:0060537 308 0.247
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.230
actin cytoskeleton organization GO:0030036 220 0.214
extracellular matrix organization GO:0030198 147 0.212
regulation of cellular amine metabolic process GO:0033238 20 0.203
locomotory behavior GO:0007626 195 0.200
Fly
cation transport GO:0006812 399 0.199
Worm
cellular amine metabolic process GO:0044106 44 0.182
positive regulation of mapk cascade GO:0043410 170 0.179
positive regulation of protein modification process GO:0031401 299 0.173
Human Rat
regulation of transferase activity GO:0051338 263 0.171
regulation of cellular ketone metabolic process GO:0010565 66 0.168
response to growth factor GO:0070848 198 0.166
Rat
anion transmembrane transport GO:0098656 71 0.155
cellular response to growth factor stimulus GO:0071363 197 0.154
Rat
t cell activation GO:0042110 289 0.152
cellular ketone metabolic process GO:0042180 84 0.144
regulation of protein serine threonine kinase activity GO:0071900 157 0.143
regulation of cell migration GO:0030334 219 0.140
Human Rat
organic anion transport GO:0015711 137 0.136
urogenital system development GO:0001655 261 0.135
acetylcholine transport GO:0015870 2 0.135
Worm
leukocyte differentiation GO:0002521 342 0.134
chemotaxis GO:0006935 247 0.130
skeletal system morphogenesis GO:0048705 203 0.130
positive regulation of apoptotic process GO:0043065 217 0.128
regulation of cellular amino acid metabolic process GO:0006521 5 0.122
camera type eye development GO:0043010 266 0.121
positive regulation of cell death GO:0010942 224 0.121
placenta development GO:0001890 140 0.121
negative regulation of molecular function GO:0044092 258 0.119
regulation of cell motility GO:2000145 236 0.117
Human Rat
stem cell differentiation GO:0048863 268 0.115
regulation of cell adhesion GO:0030155 154 0.113
regulation of secretion by cell GO:1903530 249 0.113
Rat Worm
positive regulation of transferase activity GO:0051347 167 0.111
anion transport GO:0006820 177 0.109
lymphocyte differentiation GO:0030098 242 0.109
positive regulation of protein kinase activity GO:0045860 144 0.108
synaptic transmission GO:0007268 329 0.107
Rat Worm
angiogenesis GO:0001525 201 0.106
Human
skeletal system development GO:0001501 356 0.105
cytokine production GO:0001816 319 0.104
ion transmembrane transport GO:0034220 361 0.103
kidney development GO:0001822 213 0.103
mapk cascade GO:0000165 281 0.102
embryonic organ morphogenesis GO:0048562 276 0.101
sensory organ morphogenesis GO:0090596 242 0.100
cell substrate adhesion GO:0031589 130 0.100
forebrain development GO:0030900 302 0.099
regulation of secretion GO:0051046 274 0.097
Rat Worm
positive regulation of cellular amine metabolic process GO:0033240 5 0.097
digestive system development GO:0055123 200 0.096
regulation of mapk cascade GO:0043408 248 0.094
positive regulation of kinase activity GO:0033674 155 0.091
positive regulation of programmed cell death GO:0043068 218 0.090
small gtpase mediated signal transduction GO:0007264 97 0.090
nephron epithelium development GO:0072009 92 0.089
protein maturation GO:0051604 176 0.088
telencephalon development GO:0021537 186 0.088
regulation of protein kinase activity GO:0045859 232 0.088
purine containing compound metabolic process GO:0072521 311 0.087
kidney epithelium development GO:0072073 121 0.087
transmembrane transport GO:0055085 412 0.085
positive regulation of nervous system development GO:0051962 221 0.083
Rat
regulation of hydrolase activity GO:0051336 246 0.082
regulation of establishment of protein localization GO:0070201 181 0.081
Human
skin development GO:0043588 220 0.080
ossification GO:0001503 216 0.079
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.078
mesonephric tubule development GO:0072164 94 0.078
monocarboxylic acid metabolic process GO:0032787 191 0.078
Rat
wound healing GO:0042060 157 0.077
multicellular organismal homeostasis GO:0048871 164 0.077
regulation of neuron differentiation GO:0045664 281 0.076
Rat
response to organic cyclic compound GO:0014070 198 0.076
Rat
regulation of cell cycle GO:0051726 281 0.074
Human
regulation of cell activation GO:0050865 289 0.074
cell chemotaxis GO:0060326 81 0.073
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.073
cell adhesion GO:0007155 329 0.072
epithelial tube morphogenesis GO:0060562 303 0.072
regulation of organelle organization GO:0033043 289 0.072
positive regulation of protein phosphorylation GO:0001934 242 0.071
Rat
muscle cell differentiation GO:0042692 261 0.071
regulation of actin cytoskeleton organization GO:0032956 84 0.071
gland development GO:0048732 330 0.070
regulation of cell projection organization GO:0031344 206 0.070
Rat
heart morphogenesis GO:0003007 178 0.070
macromolecule catabolic process GO:0009057 281 0.070
carbohydrate metabolic process GO:0005975 230 0.070
leukocyte migration GO:0050900 124 0.069
neurotransmitter transport GO:0006836 76 0.069
Rat Worm
regulation of apoptotic signaling pathway GO:2001233 197 0.067
acetylcholine secretion neurotransmission GO:0014055 2 0.067
Worm
purine ribonucleotide metabolic process GO:0009150 290 0.067
regulation of kinase activity GO:0043549 249 0.067
negative regulation of cell migration GO:0030336 59 0.066
organic hydroxy compound metabolic process GO:1901615 203 0.066
Human Mouse
apoptotic signaling pathway GO:0097190 306 0.066
steroid metabolic process GO:0008202 119 0.065
positive regulation of lymphocyte activation GO:0051251 140 0.065
ribonucleotide metabolic process GO:0009259 291 0.064
cardiac muscle tissue development GO:0048738 130 0.064
regulation of cell substrate adhesion GO:0010810 73 0.064
peptidyl amino acid modification GO:0018193 336 0.063
embryonic placenta development GO:0001892 98 0.063
purine nucleotide metabolic process GO:0006163 302 0.063
single organismal cell cell adhesion GO:0016337 131 0.062
mesenchyme development GO:0060485 152 0.062
leukocyte chemotaxis GO:0030595 69 0.061
regulation of cellular response to stress GO:0080135 159 0.061
regulation of protein processing GO:0070613 96 0.061
protein modification by small protein conjugation GO:0032446 187 0.061
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.061
male gamete generation GO:0048232 285 0.060
myeloid cell differentiation GO:0030099 233 0.059
membrane organization GO:0061024 245 0.059
developmental maturation GO:0021700 193 0.059
ras protein signal transduction GO:0007265 77 0.058
cartilage development GO:0051216 140 0.058
placenta blood vessel development GO:0060674 31 0.058
organic acid transport GO:0015849 101 0.058
membrane lipid metabolic process GO:0006643 53 0.058
Human Yeast Mouse Fly
thymocyte migration GO:0072679 2 0.057
morphogenesis of a branching structure GO:0001763 203 0.056
cation homeostasis GO:0055080 212 0.055
positive regulation of leukocyte differentiation GO:1902107 86 0.055
mesenchymal cell differentiation GO:0048762 107 0.055
axonogenesis GO:0007409 274 0.055
regulation of leukocyte differentiation GO:1902105 159 0.054
lung development GO:0030324 164 0.054
regulation of cytoskeleton organization GO:0051493 122 0.054
response to reactive oxygen species GO:0000302 56 0.053
Rat
myeloid leukocyte migration GO:0097529 57 0.053
regionalization GO:0003002 337 0.053
developmental growth involved in morphogenesis GO:0060560 138 0.053
reactive oxygen species metabolic process GO:0072593 84 0.052
positive regulation of cell migration GO:0030335 109 0.052
Human Rat
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.052
Human
regulation of interleukin 8 production GO:0032677 3 0.052
cellular lipid metabolic process GO:0044255 323 0.052
Human Yeast Mouse Rat Fly
negative regulation of immune system process GO:0002683 209 0.052
regulation of vesicle mediated transport GO:0060627 139 0.051
cellular response to extracellular stimulus GO:0031668 81 0.051
Rat
nucleotide metabolic process GO:0009117 332 0.050
response to organonitrogen compound GO:0010243 246 0.050
Rat
granulocyte chemotaxis GO:0071621 39 0.050
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.050
fat cell differentiation GO:0045444 160 0.050
response to transforming growth factor beta GO:0071559 88 0.049
protein ubiquitination GO:0016567 171 0.049
Human
positive regulation of cell projection organization GO:0031346 95 0.049
Rat
alcohol metabolic process GO:0006066 116 0.049
Human Mouse
organic cyclic compound catabolic process GO:1901361 295 0.048
adult behavior GO:0030534 135 0.048
Fly
negative regulation of cell motility GO:2000146 61 0.047
ribonucleoside triphosphate catabolic process GO:0009203 199 0.047
cellular homeostasis GO:0019725 240 0.047
amide transport GO:0042886 138 0.047
Human
nucleoside phosphate metabolic process GO:0006753 338 0.047
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.047
positive regulation of cellular component biogenesis GO:0044089 94 0.047
regulation of multi organism process GO:0043900 111 0.047
interleukin 8 secretion GO:0072606 3 0.046
regulation of anatomical structure size GO:0090066 178 0.046
positive regulation of t cell differentiation GO:0045582 52 0.046
muscle cell development GO:0055001 133 0.046
cell matrix adhesion GO:0007160 68 0.046
small molecule biosynthetic process GO:0044283 132 0.046
Rat
immune effector process GO:0002252 321 0.046
positive regulation of cell development GO:0010720 237 0.046
Rat
regulation of ion transport GO:0043269 215 0.045
Worm
regulation of angiogenesis GO:0045765 81 0.045
Human
morphogenesis of a branching epithelium GO:0061138 193 0.045
purine nucleotide catabolic process GO:0006195 211 0.044
nucleoside catabolic process GO:0009164 206 0.044
negative regulation of intracellular signal transduction GO:1902532 167 0.044
t cell differentiation GO:0030217 174 0.044
protein modification by small protein conjugation or removal GO:0070647 207 0.044
Human
negative regulation of cellular component organization GO:0051129 194 0.044
cation transmembrane transport GO:0098655 266 0.043
anatomical structure homeostasis GO:0060249 145 0.043
inner ear morphogenesis GO:0042472 101 0.043
cellular chemical homeostasis GO:0055082 215 0.043
connective tissue development GO:0061448 179 0.042
stress activated protein kinase signaling cascade GO:0031098 81 0.042
divalent metal ion transport GO:0070838 172 0.042
regulation of cellular component biogenesis GO:0044087 181 0.042
oxidation reduction process GO:0055114 342 0.042
negative regulation of protein processing GO:0010955 79 0.042
amino acid transmembrane transport GO:0003333 37 0.042
positive regulation of cell cycle GO:0045787 92 0.042
Human
purine nucleoside catabolic process GO:0006152 205 0.042
inflammatory response GO:0006954 244 0.041
regulation of cell size GO:0008361 72 0.041
endomembrane system organization GO:0010256 147 0.041
nephron tubule morphogenesis GO:0072078 68 0.041
cardiac chamber development GO:0003205 108 0.041
stress activated mapk cascade GO:0051403 80 0.041
metanephros development GO:0001656 79 0.041
acetate ester transport GO:1901374 2 0.040
Worm
stem cell development GO:0048864 219 0.040
regulation of muscle tissue development GO:1901861 97 0.040
positive regulation of map kinase activity GO:0043406 84 0.040
spermatogenesis GO:0007283 284 0.040
limb development GO:0060173 166 0.040
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.040
regulation of homeostatic process GO:0032844 182 0.040
purine ribonucleotide catabolic process GO:0009154 208 0.040
cell type specific apoptotic process GO:0097285 268 0.040
negative regulation of protein maturation GO:1903318 79 0.040
t cell differentiation in thymus GO:0033077 77 0.039
endocytosis GO:0006897 168 0.039
compound eye development GO:0048749 1 0.039
fibrinolysis GO:0042730 3 0.038
nucleoside metabolic process GO:0009116 246 0.038
skeletal muscle organ development GO:0060538 163 0.038
positive regulation of inflammatory response GO:0050729 47 0.038
lipid biosynthetic process GO:0008610 179 0.038
Rat
positive regulation of secretion by cell GO:1903532 114 0.038
Rat Worm
positive regulation of cell adhesion GO:0045785 80 0.038
renal tubule development GO:0061326 87 0.038
myeloid cell homeostasis GO:0002262 114 0.038
rho protein signal transduction GO:0007266 32 0.038
carboxylic acid transport GO:0046942 100 0.037
regulation of response to wounding GO:1903034 189 0.037
regulation of map kinase activity GO:0043405 120 0.037
ribonucleoside triphosphate metabolic process GO:0009199 220 0.037
extracellular structure organization GO:0043062 148 0.037
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.037
mesonephric tubule morphogenesis GO:0072171 63 0.037
cellular metal ion homeostasis GO:0006875 151 0.036
regulation of extent of cell growth GO:0061387 52 0.036
negative regulation of protein metabolic process GO:0051248 282 0.036
protein secretion GO:0009306 111 0.036
negative regulation of cytokine production GO:0001818 84 0.036
positive regulation of organelle organization GO:0010638 128 0.036
glomerulus development GO:0032835 40 0.036
regulation of chemotaxis GO:0050920 53 0.036
positive regulation of nucleoside metabolic process GO:0045979 91 0.036
regulation of reactive oxygen species metabolic process GO:2000377 40 0.035
protein processing GO:0016485 163 0.035
ribonucleoside catabolic process GO:0042454 206 0.035
nucleobase containing small molecule metabolic process GO:0055086 352 0.035
ribose phosphate metabolic process GO:0019693 291 0.035
nuclear transport GO:0051169 139 0.035
Human
regulation of monocyte chemotaxis GO:0090025 3 0.035
regulation of defense response GO:0031347 233 0.035
cellular response to external stimulus GO:0071496 88 0.035
Rat
carbohydrate derivative biosynthetic process GO:1901137 183 0.035
regulation of cellular catabolic process GO:0031329 242 0.035
regulation of cellular component size GO:0032535 121 0.034
nephron development GO:0072006 109 0.034
endocrine system development GO:0035270 98 0.034
nucleoside triphosphate catabolic process GO:0009143 205 0.034
b cell differentiation GO:0030183 78 0.034
positive regulation of cell activation GO:0050867 158 0.034
smoothened signaling pathway GO:0007224 105 0.034
positive regulation of eosinophil migration GO:2000418 2 0.034
labyrinthine layer development GO:0060711 49 0.034
myeloid leukocyte differentiation GO:0002573 119 0.034
positive regulation of stress activated mapk cascade GO:0032874 48 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.033
response to peptide GO:1901652 136 0.033
branching morphogenesis of an epithelial tube GO:0048754 159 0.033
morphogenesis of embryonic epithelium GO:0016331 159 0.033
positive regulation of t cell activation GO:0050870 101 0.033
jnk cascade GO:0007254 72 0.033
organonitrogen compound catabolic process GO:1901565 264 0.033
ureteric bud development GO:0001657 94 0.033
positive regulation of proteolysis GO:0045862 85 0.033
eosinophil migration GO:0072677 3 0.033
response to nutrient levels GO:0031667 109 0.033
Rat
epidermis development GO:0008544 187 0.033
myoblast differentiation GO:0045445 52 0.033
modification dependent macromolecule catabolic process GO:0043632 133 0.033
regulation of t cell differentiation GO:0045580 83 0.033
negative regulation of growth GO:0045926 99 0.033
ear morphogenesis GO:0042471 118 0.033
regulation of cellular response to growth factor stimulus GO:0090287 82 0.032
positive regulation of angiogenesis GO:0045766 46 0.032
Human
regulation of cell growth GO:0001558 91 0.032
Human
negative regulation of cellular protein metabolic process GO:0032269 247 0.032
t cell proliferation GO:0042098 120 0.032
cell maturation GO:0048469 127 0.032
mammary gland morphogenesis GO:0060443 54 0.032
regulation of neuron projection development GO:0010975 169 0.032
Rat
regulation of hormone levels GO:0010817 211 0.031
respiratory tube development GO:0030323 167 0.031
nucleoside triphosphate metabolic process GO:0009141 230 0.031
response to amino acid GO:0043200 37 0.031
glycosyl compound metabolic process GO:1901657 246 0.031
response to peptide hormone GO:0043434 127 0.031
leukocyte proliferation GO:0070661 172 0.031
regulation of t cell activation GO:0050863 170 0.031
palate development GO:0060021 76 0.031
purine containing compound catabolic process GO:0072523 213 0.031
cardiac muscle cell differentiation GO:0055007 69 0.030
organonitrogen compound biosynthetic process GO:1901566 192 0.030
regulation of neuron apoptotic process GO:0043523 122 0.030
mitotic cell cycle process GO:1903047 159 0.030
carbohydrate derivative catabolic process GO:1901136 231 0.030
gtp metabolic process GO:0046039 144 0.030
regulation of ossification GO:0030278 112 0.030
response to acid chemical GO:0001101 111 0.030
mitotic cell cycle GO:0000278 195 0.030
Human
regulation of protein localization GO:0032880 231 0.030
Human
neuron death GO:0070997 154 0.030
ribonucleotide catabolic process GO:0009261 208 0.030
single organism cell adhesion GO:0098602 156 0.030
sensory perception GO:0007600 245 0.030
regulation of transmembrane transport GO:0034762 128 0.030
protein localization to organelle GO:0033365 185 0.030
Human
neuron apoptotic process GO:0051402 142 0.030
cellular response to cytokine stimulus GO:0071345 189 0.030
Human
cellular response to acid chemical GO:0071229 68 0.030
response to extracellular stimulus GO:0009991 127 0.030
Rat
mesenchymal cell development GO:0014031 93 0.030
myotube differentiation GO:0014902 105 0.030
regulation of actin filament based process GO:0032970 99 0.030
regulation of inflammatory response GO:0050727 147 0.029
developmental cell growth GO:0048588 84 0.029
ureteric bud morphogenesis GO:0060675 62 0.029
limb morphogenesis GO:0035108 149 0.029
regulation of stress activated mapk cascade GO:0032872 69 0.029
interleukin 8 production GO:0032637 4 0.029
regulation of ras protein signal transduction GO:0046578 114 0.029
actin filament organization GO:0007015 113 0.029
negative regulation of synapse assembly GO:0051964 3 0.029
regulation of reproductive process GO:2000241 66 0.028
nucleotide catabolic process GO:0009166 217 0.028
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.028
Human
neuron projection extension GO:1990138 64 0.028
activation of mapk activity GO:0000187 59 0.028
glycoprotein metabolic process GO:0009100 116 0.028
regulation of cell cycle process GO:0010564 160 0.028
epithelial cell development GO:0002064 159 0.028
regulation of endocytosis GO:0030100 69 0.027
maintenance of location GO:0051235 89 0.027
tissue remodeling GO:0048771 102 0.027
nephron tubule development GO:0072080 84 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.027
response to oxidative stress GO:0006979 123 0.027
Rat
nephron epithelium morphogenesis GO:0072088 68 0.027
positive regulation of behavior GO:0048520 40 0.027
positive regulation of cell motility GO:2000147 116 0.027
Human Rat
ribonucleoside metabolic process GO:0009119 245 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.027
negative regulation of neuron projection development GO:0010977 50 0.027
mesonephros development GO:0001823 97 0.027
peptidyl tyrosine phosphorylation GO:0018108 143 0.027
negative regulation of apoptotic signaling pathway GO:2001234 104 0.027
cellular ion homeostasis GO:0006873 165 0.027
purine nucleoside triphosphate metabolic process GO:0009144 226 0.026
regulation of thymocyte migration GO:2000410 2 0.026
regulation of neuron death GO:1901214 134 0.026
epithelial cell proliferation GO:0050673 174 0.026
negative regulation of response to wounding GO:1903035 77 0.026
negative regulation of cell proliferation GO:0008285 296 0.026
development of primary sexual characteristics GO:0045137 143 0.026
negative regulation of phosphorus metabolic process GO:0010563 184 0.026
mesonephric epithelium development GO:0072163 94 0.026
digestive tract development GO:0048565 190 0.026
negative regulation of cell adhesion GO:0007162 45 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.026
appendage development GO:0048736 166 0.026
regulation of lipid metabolic process GO:0019216 118 0.026
positive regulation of cellular catabolic process GO:0031331 148 0.026
negative regulation of hydrolase activity GO:0051346 71 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.026
glial cell differentiation GO:0010001 131 0.026
gliogenesis GO:0042063 141 0.026
negative regulation of proteolysis GO:0045861 74 0.026
cell junction organization GO:0034330 77 0.025
neutrophil chemotaxis GO:0030593 36 0.025
phospholipid metabolic process GO:0006644 87 0.025
regulation of vasculature development GO:1901342 88 0.025
Human
nerve development GO:0021675 67 0.025
positive regulation of leukocyte proliferation GO:0070665 73 0.025
ventricular septum development GO:0003281 42 0.025
positive regulation of neuron projection development GO:0010976 79 0.025
Rat
glycosyl compound catabolic process GO:1901658 206 0.025
lateral inhibition GO:0046331 1 0.025
establishment of protein localization to organelle GO:0072594 118 0.025
Human
calcium ion transport GO:0006816 159 0.025
lipid transport GO:0006869 98 0.025
adult locomotory behavior GO:0008344 91 0.024
Fly
aromatic compound catabolic process GO:0019439 286 0.024
protein catabolic process GO:0030163 221 0.024
organelle localization GO:0051640 179 0.024
gonad development GO:0008406 141 0.024
ameboidal type cell migration GO:0001667 128 0.024
actin filament bundle assembly GO:0051017 40 0.024
neuromuscular process GO:0050905 99 0.024
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.024
neuron migration GO:0001764 122 0.024
negative regulation of fat cell differentiation GO:0045599 36 0.024
microglia development GO:0014005 2 0.024
regulation of peptidase activity GO:0052547 96 0.024
positive regulation of epithelial cell proliferation GO:0050679 68 0.024
cellular protein catabolic process GO:0044257 155 0.024
epithelial cell migration GO:0010631 63 0.024
metal ion homeostasis GO:0055065 189 0.024
regulation of ion transmembrane transport GO:0034765 119 0.024
regulation of body fluid levels GO:0050878 162 0.024
striated muscle cell development GO:0055002 125 0.024
extrinsic apoptotic signaling pathway GO:0097191 126 0.023
positive regulation of homeostatic process GO:0032846 64 0.023
pallium development GO:0021543 120 0.023
organophosphate catabolic process GO:0046434 232 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
peptidyl tyrosine modification GO:0018212 145 0.023
organic hydroxy compound biosynthetic process GO:1901617 77 0.023
prostaglandin metabolic process GO:0006693 11 0.023
Rat
muscle system process GO:0003012 141 0.023
Human
regulation of protein kinase b signaling GO:0051896 56 0.023
kidney morphogenesis GO:0060993 83 0.022
guanosine containing compound catabolic process GO:1901069 144 0.022
germ cell development GO:0007281 185 0.022
regulation of gtp catabolic process GO:0033124 113 0.022
organelle fission GO:0048285 170 0.022
regulation of intracellular protein transport GO:0033157 82 0.022
Human
microtubule based process GO:0007017 236 0.022
cytokine mediated signaling pathway GO:0019221 115 0.022
Human
trabecula morphogenesis GO:0061383 40 0.022
myeloid leukocyte activation GO:0002274 83 0.022
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.022
bone development GO:0060348 120 0.022
cell fate commitment GO:0045165 210 0.022
regulation of fat cell differentiation GO:0045598 81 0.022
regulation of eosinophil migration GO:2000416 2 0.022
hindbrain development GO:0030902 128 0.022
cellular amide metabolic process GO:0043603 58 0.022
cardiocyte differentiation GO:0035051 87 0.022
divalent inorganic cation transport GO:0072511 178 0.021
tube formation GO:0035148 140 0.021
stem cell proliferation GO:0072089 117 0.021
engulfment of apoptotic cell GO:0043652 3 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
neural crest cell development GO:0014032 48 0.021
icosanoid metabolic process GO:0006690 33 0.021
Rat
response to lipopolysaccharide GO:0032496 128 0.021
positive regulation of neuron differentiation GO:0045666 141 0.021
Rat
gtp catabolic process GO:0006184 143 0.021
respiratory system development GO:0060541 190 0.021
response to inorganic substance GO:0010035 96 0.021
Rat
positive regulation of lymphocyte differentiation GO:0045621 61 0.021
protein localization to membrane GO:0072657 108 0.021
regulation of nuclear division GO:0051783 56 0.021
regulation of interleukin 1 beta production GO:0032651 25 0.021
metencephalon development GO:0022037 89 0.021
carbohydrate transport GO:0008643 62 0.021
lipid localization GO:0010876 126 0.021
cell recognition GO:0008037 83 0.021
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.021
meiotic cell cycle GO:0051321 122 0.021
hepaticobiliary system development GO:0061008 67 0.021
innate immune response GO:0045087 157 0.021
positive regulation of jnk cascade GO:0046330 46 0.020
erythrocyte differentiation GO:0030218 88 0.020
regulation of protein import into nucleus GO:0042306 52 0.020
Human
peptide metabolic process GO:0006518 46 0.020
leukocyte apoptotic process GO:0071887 71 0.020
exocytosis GO:0006887 121 0.020
liver development GO:0001889 66 0.020
leukocyte mediated immunity GO:0002443 174 0.020
regulation of jnk cascade GO:0046328 62 0.020
respiratory gaseous exchange GO:0007585 43 0.020
regulation of protein maturation GO:1903317 96 0.020
regulation of lymphocyte differentiation GO:0045619 107 0.020
negative regulation of cell growth GO:0030308 44 0.020
hexose metabolic process GO:0019318 98 0.020
multi multicellular organism process GO:0044706 109 0.020
Rat Fly
regulation of leukocyte proliferation GO:0070663 121 0.020
positive regulation of thymocyte migration GO:2000412 2 0.020
immune response activating signal transduction GO:0002757 116 0.020
carboxylic acid biosynthetic process GO:0046394 86 0.020
Rat
renal tubule morphogenesis GO:0061333 72 0.020
positive regulation of stem cell proliferation GO:2000648 59 0.020
spleen development GO:0048536 39 0.020
positive regulation of protein kinase b signaling GO:0051897 32 0.020
modification dependent protein catabolic process GO:0019941 133 0.020
negative regulation of leukocyte differentiation GO:1902106 51 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
Human
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
cytoplasmic transport GO:0016482 234 0.019
Human
cytokine metabolic process GO:0042107 71 0.019

Sphk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
sensory system disease DOID:0050155 0 0.020