Mus musculus

104 known processes

Spna1

spectrin alpha 1

(Aliases: ihj,sph,nmf4,Spta1,Spna-1,AF093576,ha,AI451697)

Spna1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
erythrocyte differentiation GO:0030218 88 1.000
transition metal ion homeostasis GO:0055076 54 1.000
tetrapyrrole metabolic process GO:0033013 22 1.000
myeloid cell homeostasis GO:0002262 114 0.999
erythrocyte maturation GO:0043249 6 0.999
homeostasis of number of cells GO:0048872 210 0.999
regulation of translational initiation in response to stress GO:0043558 5 0.998
porphyrin containing compound biosynthetic process GO:0006779 16 0.997
tetrapyrrole biosynthetic process GO:0033014 16 0.997
iron ion homeostasis GO:0055072 36 0.994
cofactor metabolic process GO:0051186 80 0.991
myeloid cell differentiation GO:0030099 233 0.990
cofactor biosynthetic process GO:0051188 41 0.990
positive regulation of potassium ion transmembrane transporter activity GO:1901018 1 0.954
multicellular organismal iron ion homeostasis GO:0060586 8 0.927
response to iron ion GO:0010039 4 0.915
metal ion homeostasis GO:0055065 189 0.908
cation homeostasis GO:0055080 212 0.852
cellular component assembly involved in morphogenesis GO:0010927 139 0.834
cellular ion homeostasis GO:0006873 165 0.828
translational initiation GO:0006413 24 0.826
inorganic ion transmembrane transport GO:0098660 234 0.771
heme biosynthetic process GO:0006783 12 0.747
cation transport GO:0006812 399 0.714
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 10 0.703
t cell proliferation GO:0042098 120 0.688
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.667
porphyrin containing compound metabolic process GO:0006778 22 0.653
negative regulation of complement activation GO:0045916 3 0.625
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 12 0.609
cellular amino acid metabolic process GO:0006520 103 0.603
cellular homeostasis GO:0019725 240 0.601
acute inflammatory response GO:0002526 41 0.579
regulation of microvillus organization GO:0032530 3 0.556
maintenance of location GO:0051235 89 0.525
regulation of erythrocyte differentiation GO:0045646 23 0.522
regulation of cytokine production GO:0001817 266 0.518
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0010881 7 0.508
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 12 0.490
organelle assembly GO:0070925 177 0.475
immune effector process GO:0002252 321 0.475
hindbrain development GO:0030902 128 0.471
sa node cell action potential GO:0086015 4 0.463
anion transport GO:0006820 177 0.451
regulation of cellular amino acid metabolic process GO:0006521 5 0.448
negative regulation of cellular amine metabolic process GO:0033239 1 0.447
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.431
inflammatory response GO:0006954 244 0.428
protein targeting to membrane GO:0006612 20 0.426
protein processing GO:0016485 163 0.410
transmembrane transport GO:0055085 412 0.403
proton transport GO:0015992 35 0.401
cell recognition GO:0008037 83 0.393
protein import GO:0017038 101 0.383
activation of cysteine type endopeptidase activity GO:0097202 27 0.377
regulation of mast cell proliferation GO:0070666 4 0.365
negative regulation of heart rate GO:0010459 4 0.363
cytokine production GO:0001816 319 0.363
defense response to other organism GO:0098542 197 0.363
negative regulation of protein activation cascade GO:2000258 3 0.361
ion transmembrane transport GO:0034220 361 0.355
muscle adaptation GO:0043500 39 0.355
regulation of cellular response to stress GO:0080135 159 0.344
regulation of calcium ion transmembrane transport GO:1903169 20 0.344
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.344
regulation of ph GO:0006885 26 0.340
inorganic cation transmembrane transport GO:0098662 207 0.340
meiotic cell cycle process GO:1903046 77 0.337
neuron projection guidance GO:0097485 141 0.336
protein localization to plasma membrane GO:0072659 57 0.333
cerebellar purkinje cell layer development GO:0021680 26 0.324
b cell differentiation GO:0030183 78 0.316
multicellular organism growth GO:0035264 161 0.315
Worm
protein targeting to plasma membrane GO:0072661 7 0.314
positive regulation of potassium ion transport GO:0043268 3 0.312
digestive system development GO:0055123 200 0.310
regulation of cellular ketone metabolic process GO:0010565 66 0.308
lymphocyte homeostasis GO:0002260 64 0.308
t cell mediated immunity GO:0002456 50 0.304
chemotaxis GO:0006935 247 0.297
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.295
regulation of intracellular ph GO:0051453 11 0.283
production of molecular mediator of immune response GO:0002440 103 0.281
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.274
regulation of fibroblast growth factor production GO:0090270 4 0.272
sequestering of metal ion GO:0051238 19 0.272
developmental maturation GO:0021700 193 0.271
Zebrafish
glutathione metabolic process GO:0006749 16 0.266
metencephalon development GO:0022037 89 0.265
cation transmembrane transport GO:0098655 266 0.264
release of sequestered calcium ion into cytosol GO:0051209 42 0.260
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.257
activation of immune response GO:0002253 138 0.257
cellular ketone metabolic process GO:0042180 84 0.254
leukocyte activation involved in immune response GO:0002366 126 0.254
response to starvation GO:0042594 65 0.249
response to light stimulus GO:0009416 135 0.247
male gamete generation GO:0048232 285 0.245
positive regulation of innate immune response GO:0045089 80 0.241
cellular amine metabolic process GO:0044106 44 0.240
regulation of peptidyl lysine acetylation GO:2000756 22 0.236
regulation of transcription from rna polymerase ii promoter in response to iron GO:0034395 3 0.235
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.233
regulation of homeostatic process GO:0032844 182 0.231
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.231
negative regulation of heart contraction GO:0045822 11 0.228
actin filament based movement GO:0030048 23 0.224
positive regulation of potassium ion transmembrane transport GO:1901381 3 0.216
actomyosin structure organization GO:0031032 56 0.216
regulation of eif2 alpha phosphorylation by heme GO:0010999 3 0.213
response to radiation GO:0009314 165 0.210
transmission of nerve impulse GO:0019226 76 0.210
leukocyte homeostasis GO:0001776 79 0.210
amine metabolic process GO:0009308 45 0.208
cellular response to cytokine stimulus GO:0071345 189 0.206
positive regulation of endopeptidase activity GO:0010950 43 0.201
urogenital system development GO:0001655 261 0.200
actin mediated cell contraction GO:0070252 15 0.197
cell activation involved in immune response GO:0002263 126 0.197
cellular metal ion homeostasis GO:0006875 151 0.196
embryonic hemopoiesis GO:0035162 23 0.194
regulation of leukocyte differentiation GO:1902105 159 0.189
arginine transport GO:0015809 4 0.188
protein maturation GO:0051604 176 0.187
protein import into nucleus translocation GO:0000060 12 0.184
microtubule cytoskeleton organization GO:0000226 157 0.182
leukocyte mediated cytotoxicity GO:0001909 62 0.180
striated muscle adaptation GO:0014888 26 0.180
regulation of reactive oxygen species metabolic process GO:2000377 40 0.179
regulation of t cell differentiation GO:0045580 83 0.177
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.174
negative regulation of syncytium formation by plasma membrane fusion GO:0034242 5 0.174
activation of membrane attack complex GO:0001905 4 0.174
cardiac muscle cell action potential involved in contraction GO:0086002 6 0.167
monovalent inorganic cation homeostasis GO:0055067 33 0.164
regulation of actin filament based process GO:0032970 99 0.164
innate immune response GO:0045087 157 0.164
regulation of microvillus assembly GO:0032534 3 0.161
membrane organization GO:0061024 245 0.161
negative regulation of glycolytic process GO:0045820 4 0.159
axon guidance GO:0007411 141 0.159
negative regulation of homeostatic process GO:0032845 71 0.158
cellular response to lipopolysaccharide GO:0071222 77 0.158
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.158
organonitrogen compound biosynthetic process GO:1901566 192 0.157
digestive tract development GO:0048565 190 0.156
multicellular organismal homeostasis GO:0048871 164 0.154
positive regulation of defense response GO:0031349 124 0.154
zymogen activation GO:0031638 41 0.151
humoral immune response GO:0006959 57 0.150
stem cell maintenance GO:0019827 130 0.150
regulation of myeloid cell differentiation GO:0045637 96 0.147
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.145
jak stat cascade involved in growth hormone signaling pathway GO:0060397 4 0.145
axon ensheathment GO:0008366 76 0.144
cellular transition metal ion homeostasis GO:0046916 32 0.143
protein polymerization GO:0051258 57 0.143
cardiac conduction GO:0061337 17 0.140
regulation of ion homeostasis GO:2000021 64 0.139
respiratory burst GO:0045730 8 0.138
regulation of cellular amine metabolic process GO:0033238 20 0.137
muscle system process GO:0003012 141 0.137
copper ion transmembrane transport GO:0035434 5 0.135
negative regulation of neuron apoptotic process GO:0043524 92 0.135
negative regulation of immune system process GO:0002683 209 0.135
striated muscle cell development GO:0055002 125 0.135
lipid homeostasis GO:0055088 63 0.133
embryonic placenta development GO:0001892 98 0.132
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.131
regulation of inflammatory response GO:0050727 147 0.130
myeloid leukocyte differentiation GO:0002573 119 0.130
wound healing GO:0042060 157 0.129
regulation of peptidase activity GO:0052547 96 0.129
sequestering of calcium ion GO:0051208 18 0.127
negative regulation of protein metabolic process GO:0051248 282 0.124
multicellular organismal signaling GO:0035637 91 0.123
muscle cell development GO:0055001 133 0.123
central nervous system neuron axonogenesis GO:0021955 28 0.120
hemoglobin biosynthetic process GO:0042541 7 0.118
organic anion transport GO:0015711 137 0.117
regulation of mast cell differentiation GO:0060375 3 0.116
blood coagulation GO:0007596 76 0.116
regulation of cardiac muscle cell membrane potential GO:0086036 3 0.116
alpha beta t cell activation GO:0046631 91 0.115
positive regulation of lymphocyte proliferation GO:0050671 70 0.115
heart contraction GO:0060047 93 0.114
regulation of lymphocyte mediated immunity GO:0002706 84 0.114
cytoskeletal anchoring at plasma membrane GO:0007016 2 0.114
regulation of cellular ph GO:0030641 12 0.114
learning or memory GO:0007611 148 0.114
response to interleukin 15 GO:0070672 3 0.113
positive regulation of calcium ion transport GO:0051928 27 0.113
reactive oxygen species metabolic process GO:0072593 84 0.113
leukocyte mediated immunity GO:0002443 174 0.112
heme metabolic process GO:0042168 16 0.111
photoreceptor cell differentiation GO:0046530 52 0.111
eye photoreceptor cell differentiation GO:0001754 41 0.110
positive regulation of adaptive immune response GO:0002821 61 0.109
regulation of b cell differentiation GO:0045577 23 0.109
regulation of intracellular transport GO:0032386 159 0.109
positive regulation of peptidase activity GO:0010952 49 0.109
immune response activating signal transduction GO:0002757 116 0.108
axonogenesis GO:0007409 274 0.107
sensory perception of mechanical stimulus GO:0050954 107 0.107
posttranscriptional regulation of gene expression GO:0010608 155 0.106
neuronal action potential GO:0019228 54 0.106
response to extracellular stimulus GO:0009991 127 0.105
protein localization to organelle GO:0033365 185 0.103
development of secondary male sexual characteristics GO:0046544 3 0.101
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.100
regulation of defense response GO:0031347 233 0.100
neural tube closure GO:0001843 90 0.100
cellular amide metabolic process GO:0043603 58 0.099
lymphocyte activation involved in immune response GO:0002285 93 0.099
visual perception GO:0007601 52 0.098
endomembrane system organization GO:0010256 147 0.098
long term memory GO:0007616 15 0.097
regulation of natural killer cell mediated immunity GO:0002715 19 0.096
fibrinolysis GO:0042730 3 0.095
positive regulation of erythrocyte differentiation GO:0045648 11 0.094
reactive oxygen species biosynthetic process GO:1903409 8 0.094
t cell activation GO:0042110 289 0.094
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 9 0.093
endoplasmic reticulum to cytosol transport GO:1903513 12 0.092
regulation of histone h3 k4 methylation GO:0051569 12 0.091
regulation of innate immune response GO:0045088 91 0.091
lipid storage GO:0019915 36 0.090
hydrogen ion transmembrane transport GO:1902600 25 0.090
hemoglobin metabolic process GO:0020027 13 0.090
atrial cardiac muscle cell to av node cell signaling GO:0086026 2 0.090
protein localization to membrane GO:0072657 108 0.089
regulation of adaptive immune response GO:0002819 90 0.089
coagulation GO:0050817 78 0.089
regulation of natural killer cell differentiation GO:0032823 11 0.089
natural killer cell mediated cytotoxicity GO:0042267 29 0.089
response to oxidative stress GO:0006979 123 0.088
progesterone metabolic process GO:0042448 4 0.088
regulation of body fluid levels GO:0050878 162 0.088
cell adhesion GO:0007155 329 0.087
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.087
syncytium formation by plasma membrane fusion GO:0000768 42 0.087
negative regulation of immune effector process GO:0002698 55 0.087
protein stabilization GO:0050821 25 0.087
spermatogenesis GO:0007283 284 0.085
regulation of cytoplasmic transport GO:1903649 112 0.084
negative regulation of vascular endothelial growth factor receptor signaling pathway GO:0030948 6 0.083
protein acylation GO:0043543 64 0.083
cell killing GO:0001906 67 0.081
regulation of plasma lipoprotein particle levels GO:0097006 23 0.081
regulation of protein stability GO:0031647 52 0.080
mast cell differentiation GO:0060374 5 0.080
cellular response to arsenic containing substance GO:0071243 4 0.080
response to lipopolysaccharide GO:0032496 128 0.080
common partner smad protein phosphorylation GO:0007182 2 0.079
peptidyl amino acid modification GO:0018193 336 0.078
response to molecule of bacterial origin GO:0002237 143 0.078
protein localization to nucleus GO:0034504 121 0.078
regulation of anatomical structure size GO:0090066 178 0.078
cerebellar cortex development GO:0021695 48 0.077
leukocyte proliferation GO:0070661 172 0.076
regulation of translational initiation GO:0006446 15 0.076
inorganic anion transmembrane transport GO:0098661 29 0.076
sensory organ morphogenesis GO:0090596 242 0.076
regulation of cellular component size GO:0032535 121 0.075
dendritic cell antigen processing and presentation GO:0002468 7 0.075
potassium ion transmembrane transport GO:0071805 43 0.075
sa node cell to atrial cardiac muscle cell communication GO:0086070 5 0.075
protein secretion GO:0009306 111 0.075
lymphocyte mediated immunity GO:0002449 139 0.074
hydrogen transport GO:0006818 35 0.073
central nervous system neuron differentiation GO:0021953 162 0.073
regulation of actin polymerization or depolymerization GO:0008064 45 0.072
cellular iron ion homeostasis GO:0006879 16 0.072
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.071
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.071
cytoplasmic transport GO:0016482 234 0.071
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.071
cellular response to erythropoietin GO:0036018 1 0.070
epithelial cell development GO:0002064 159 0.069
adaptive immune response GO:0002250 155 0.069
sodium ion transport GO:0006814 73 0.069
potassium ion transport GO:0006813 52 0.069
single organism nuclear import GO:1902593 95 0.069
regulation of leukocyte mediated immunity GO:0002703 104 0.069
cellular response to growth factor stimulus GO:0071363 197 0.069
primary neural tube formation GO:0014020 95 0.068
regulation of response to wounding GO:1903034 189 0.068
retina vasculature development in camera type eye GO:0061298 17 0.067
positive regulation of synaptic plasticity GO:0031915 4 0.067
lymphocyte proliferation GO:0046651 164 0.067
response to growth factor GO:0070848 198 0.067
positive regulation of b cell mediated immunity GO:0002714 26 0.066
chromatin modification GO:0016568 187 0.066
negative regulation of humoral immune response GO:0002921 6 0.066
negative regulation of cell activation GO:0050866 111 0.065
positive regulation of cytokine production GO:0001819 174 0.065
regulation of cell cycle GO:0051726 281 0.065
regulation of antimicrobial humoral response GO:0002759 3 0.065
fertilization GO:0009566 127 0.065
positive regulation of cell killing GO:0031343 33 0.064
positive regulation of immune effector process GO:0002699 107 0.063
negative regulation of cytokine production GO:0001818 84 0.063
amino acid transport GO:0006865 61 0.063
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.063
interferon gamma production GO:0032609 67 0.063
nucleocytoplasmic transport GO:0006913 139 0.062
regulation of protein localization GO:0032880 231 0.062
sarcomere organization GO:0045214 24 0.061
positive regulation of myeloid cell differentiation GO:0045639 43 0.061
actin polymerization or depolymerization GO:0008154 54 0.061
positive regulation of cell motility GO:2000147 116 0.061
striated muscle tissue development GO:0014706 293 0.061
cellular response to granulocyte macrophage colony stimulating factor stimulus GO:0097011 3 0.061
regulation of vesicle mediated transport GO:0060627 139 0.060
positive regulation of t cell proliferation GO:0042102 52 0.060
detection of stimulus GO:0051606 84 0.060
regionalization GO:0003002 337 0.059
oocyte construction GO:0007308 2 0.059
angiogenesis GO:0001525 201 0.058
negative regulation of coagulation GO:0050819 11 0.058
glial cell differentiation GO:0010001 131 0.057
cell maturation GO:0048469 127 0.057
Zebrafish
circulatory system process GO:0003013 197 0.057
regulation of lymphocyte activation GO:0051249 240 0.057
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.057
development of primary sexual characteristics GO:0045137 143 0.056
divalent metal ion transport GO:0070838 172 0.056
regulation of protein acetylation GO:1901983 22 0.056
organic acid transport GO:0015849 101 0.056
isotype switching to ige isotypes GO:0048289 7 0.056
gliogenesis GO:0042063 141 0.055
calcium ion transport into cytosol GO:0060402 48 0.055
myosin filament organization GO:0031033 3 0.055
negative regulation of erythrocyte differentiation GO:0045647 5 0.054
mast cell proliferation GO:0070662 4 0.054
regulation of proteolysis GO:0030162 164 0.053
oxidation reduction process GO:0055114 342 0.053
acute phase response GO:0006953 10 0.052
very low density lipoprotein particle assembly GO:0034379 2 0.052
regulation of translational initiation by eif2 alpha phosphorylation GO:0010998 3 0.052
positive regulation of gamma delta t cell activation GO:0046645 6 0.052
divalent inorganic cation transport GO:0072511 178 0.051
regulation of organelle organization GO:0033043 289 0.051
positive regulation of phagocytosis engulfment GO:0060100 3 0.051
nuclear import GO:0051170 95 0.051
regulation of humoral immune response GO:0002920 22 0.050
hemangioblast cell differentiation GO:0060217 1 0.050
pigment metabolic process GO:0042440 32 0.050
striated muscle myosin thick filament assembly GO:0071688 1 0.050
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.049
response to decreased oxygen levels GO:0036293 59 0.049
response to erythropoietin GO:0036017 1 0.049
synapse organization GO:0050808 125 0.048
actin filament polymerization GO:0030041 44 0.048
dna recombination GO:0006310 92 0.048
regulation of sodium ion transport GO:0002028 29 0.048
regulation of t cell activation GO:0050863 170 0.048
intracellular protein transport GO:0006886 204 0.048
regulation of calcium ion transport into cytosol GO:0010522 31 0.048
regulation of alpha beta t cell activation GO:0046634 53 0.047
interleukin 2 production GO:0032623 33 0.047
regulation of translation in response to stress GO:0043555 5 0.047
multi multicellular organism process GO:0044706 109 0.046
regulation of leukocyte apoptotic process GO:2000106 56 0.046
regulation of hemostasis GO:1900046 28 0.046
alpha beta t cell differentiation GO:0046632 69 0.046
positive regulation of calcium ion transmembrane transporter activity GO:1901021 8 0.046
positive regulation of t cell differentiation GO:0045582 52 0.046
digestive tract morphogenesis GO:0048546 147 0.046
positive regulation of lymphocyte differentiation GO:0045621 61 0.045
bmp signaling pathway GO:0030509 93 0.045
natural killer cell proliferation GO:0001787 3 0.045
translation GO:0006412 93 0.045
positive regulation of t cell activation GO:0050870 101 0.045
cytokine mediated signaling pathway GO:0019221 115 0.045
regulation of cytokine biosynthetic process GO:0042035 59 0.045
regulation of ion transport GO:0043269 215 0.044
stem cell differentiation GO:0048863 268 0.044
carboxylic acid transport GO:0046942 100 0.044
actin cytoskeleton organization GO:0030036 220 0.044
regulation of blood coagulation GO:0030193 28 0.044
regulation of cardiac muscle cell contraction GO:0086004 11 0.044
dna metabolic process GO:0006259 303 0.044
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.043
muscle cell differentiation GO:0042692 261 0.043
negative regulation of adaptive immune response GO:0002820 25 0.043
cellular response to x ray GO:0071481 2 0.043
megakaryocyte differentiation GO:0030219 26 0.043
establishment of protein localization to plasma membrane GO:0090002 34 0.042
response to organic cyclic compound GO:0014070 198 0.042
negative regulation of response to biotic stimulus GO:0002832 10 0.042
regulation of cysteine type endopeptidase activity GO:2000116 65 0.042
regulation of translation GO:0006417 71 0.042
immunoglobulin production GO:0002377 73 0.042
myeloid leukocyte migration GO:0097529 57 0.042
cellular response to inorganic substance GO:0071241 37 0.041
plasma lipoprotein particle organization GO:0071827 11 0.041
blood circulation GO:0008015 195 0.041
response to inorganic substance GO:0010035 96 0.041
positive regulation of growth GO:0045927 104 0.041
Worm
hexose transport GO:0008645 56 0.041
somatic diversification of immunoglobulins GO:0016445 43 0.041
positive regulation of organelle organization GO:0010638 128 0.040
nuclear transport GO:0051169 139 0.040
locomotory behavior GO:0007626 195 0.040
action potential GO:0001508 78 0.040
regulation of gamma delta t cell differentiation GO:0045586 9 0.040
regulation of isotype switching to ige isotypes GO:0048293 7 0.040
retina vasculature morphogenesis in camera type eye GO:0061299 10 0.040
regulation of mast cell apoptotic process GO:0033025 5 0.039
regulation of cytolysis GO:0042268 1 0.039
regulation of removal of superoxide radicals GO:2000121 4 0.039
hemostasis GO:0007599 78 0.039
organ regeneration GO:0031100 2 0.039
erythropoietin mediated signaling pathway GO:0038162 1 0.039
t cell differentiation in thymus GO:0033077 77 0.039
positive regulation of actin filament polymerization GO:0030838 26 0.039
t cell differentiation GO:0030217 174 0.038
pyramidal neuron differentiation GO:0021859 9 0.038
response to oxygen levels GO:0070482 62 0.038
protein localization to juxtaparanode region of axon GO:0071205 4 0.038
regulation of complement activation GO:0030449 7 0.038
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.038
positive regulation of phagocytosis GO:0050766 26 0.038
atrial cardiac muscle cell to av node cell communication GO:0086066 2 0.038
positive regulation of hydrolase activity GO:0051345 148 0.037
heart process GO:0003015 94 0.037
citrate metabolic process GO:0006101 3 0.037
positive regulation of mast cell proliferation GO:0070668 3 0.036
regulation of hormone levels GO:0010817 211 0.036
fibroblast growth factor production GO:0090269 4 0.036
wound healing involved in inflammatory response GO:0002246 4 0.036
positive regulation of proteolysis GO:0045862 85 0.036
leukocyte differentiation GO:0002521 342 0.036
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.036
regulation of dendritic cell cytokine production GO:0002730 2 0.035
positive regulation of leukocyte differentiation GO:1902107 86 0.035
regulation of wound healing GO:0061041 40 0.035
ensheathment of neurons GO:0007272 76 0.035
ear development GO:0043583 200 0.035
defense response to virus GO:0051607 68 0.035
cardiac muscle cell contraction GO:0086003 7 0.035
chromatin organization GO:0006325 206 0.035
gland development GO:0048732 330 0.035
negative regulation of blood vessel morphogenesis GO:2000181 25 0.034
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.034
establishment or maintenance of cell polarity GO:0007163 86 0.034
cd4 positive alpha beta t cell activation GO:0035710 45 0.034
apical constriction GO:0003383 4 0.034
cardiac muscle hypertrophy GO:0003300 23 0.034
regulation of myeloid leukocyte differentiation GO:0002761 58 0.034
skeletal muscle organ development GO:0060538 163 0.034
post embryonic organ development GO:0048569 17 0.034
regulation of dna recombination GO:0000018 34 0.034
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.034
pons development GO:0021548 13 0.034
regulation of blood circulation GO:1903522 93 0.034
cellular response to nutrient levels GO:0031669 64 0.034
regulation of membrane potential GO:0042391 192 0.034
embryonic epithelial tube formation GO:0001838 130 0.034
protein targeting GO:0006605 143 0.033
memory GO:0007613 58 0.033
hydrogen peroxide catabolic process GO:0042744 5 0.033
cytokine production involved in immune response GO:0002367 34 0.033
positive regulation of cellular ph reduction GO:0032849 2 0.033
alcohol metabolic process GO:0006066 116 0.033
homeostasis of number of cells within a tissue GO:0048873 25 0.033
nitric oxide metabolic process GO:0046209 25 0.033
regulation of lymphocyte differentiation GO:0045619 107 0.033
regulation of cell killing GO:0031341 40 0.032
killing by host of symbiont cells GO:0051873 11 0.032
actin filament organization GO:0007015 113 0.032
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.032
epidermis development GO:0008544 187 0.032
response to hypoxia GO:0001666 58 0.032
carbohydrate transport GO:0008643 62 0.032
sensory perception of light stimulus GO:0050953 54 0.032
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.032
negative regulation of cell proliferation GO:0008285 296 0.032

Spna1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 1.000
Human
normocytic anemia DOID:720 0 1.000
Human
disease of anatomical entity DOID:7 0 1.000
Human
anemia DOID:2355 0 1.000
Human
hematopoietic system disease DOID:74 0 1.000
Human
hemolytic anemia DOID:583 0 0.996
Human
congenital hemolytic anemia DOID:589 0 0.771
Human
disease of metabolism DOID:0014667 0 0.162
inherited metabolic disorder DOID:655 0 0.162
cancer DOID:162 0 0.107
disease of cellular proliferation DOID:14566 0 0.107
organ system cancer DOID:0050686 0 0.107
metal metabolism disorder DOID:896 0 0.098
blood platelet disease DOID:2218 0 0.070
hemorrhagic disease DOID:2213 0 0.070
blood coagulation disease DOID:1247 0 0.070
nervous system disease DOID:863 0 0.057
central nervous system disease DOID:331 0 0.048