Mus musculus

26 known processes

Spock1

sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1

(Aliases: testican,Ticn1,Spock)

Spock1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 329 0.430
regulation of neuron projection development GO:0010975 169 0.421
Human
regulation of cell motility GO:2000145 236 0.419
Mouse
axonogenesis GO:0007409 274 0.399
eye photoreceptor cell differentiation GO:0001754 41 0.369
regulation of synaptic plasticity GO:0048167 87 0.333
regulation of cellular amino acid metabolic process GO:0006521 5 0.325
cell division GO:0051301 120 0.309
positive regulation of nervous system development GO:0051962 221 0.283
regulation of cell projection organization GO:0031344 206 0.252
Human
negative regulation of protein modification process GO:0031400 163 0.235
cation transport GO:0006812 399 0.229
regulation of transmembrane transport GO:0034762 128 0.221
g protein coupled receptor signaling pathway GO:0007186 243 0.218
regulation of ion transport GO:0043269 215 0.204
positive regulation of vesicle fusion GO:0031340 2 0.202
response to radiation GO:0009314 165 0.198
positive regulation of cell development GO:0010720 237 0.197
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.196
synapse organization GO:0050808 125 0.191
developmental maturation GO:0021700 193 0.191
locomotory behavior GO:0007626 195 0.189
photoreceptor cell differentiation GO:0046530 52 0.179
positive regulation of neuron projection development GO:0010976 79 0.177
ion transmembrane transport GO:0034220 361 0.175
peptidyl tyrosine phosphorylation GO:0018108 143 0.169
Mouse
membrane organization GO:0061024 245 0.167
amine metabolic process GO:0009308 45 0.166
cation transmembrane transport GO:0098655 266 0.163
regulation of cellular ketone metabolic process GO:0010565 66 0.162
positive regulation of cell projection organization GO:0031346 95 0.157
muscle tissue development GO:0060537 308 0.149
transmembrane transport GO:0055085 412 0.148
regulation of cellular amine metabolic process GO:0033238 20 0.148
regulation of body fluid levels GO:0050878 162 0.147
positive regulation of secretion by cell GO:1903532 114 0.147
regulation of neuron differentiation GO:0045664 281 0.146
Human
cellular amine metabolic process GO:0044106 44 0.146
cellular amino acid metabolic process GO:0006520 103 0.145
peptidyl tyrosine modification GO:0018212 145 0.141
Mouse
cell maturation GO:0048469 127 0.141
regulation of membrane potential GO:0042391 192 0.139
cellular ketone metabolic process GO:0042180 84 0.139
negative regulation of cell development GO:0010721 169 0.135
Human
regulation of secretion GO:0051046 274 0.132
inorganic ion transmembrane transport GO:0098660 234 0.124
organelle localization GO:0051640 179 0.124
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.123
long term synaptic potentiation GO:0060291 25 0.123
negative regulation of molecular function GO:0044092 258 0.123
Human
epithelial cell development GO:0002064 159 0.122
positive regulation of protein modification process GO:0031401 299 0.122
Mouse
regulation of cellular component size GO:0032535 121 0.122
cellular potassium ion transport GO:0071804 43 0.120
regulation of transferase activity GO:0051338 263 0.119
camera type eye development GO:0043010 266 0.117
establishment of vesicle localization GO:0051650 81 0.116
regulation of peptidase activity GO:0052547 96 0.115
Human
gliogenesis GO:0042063 141 0.115
skin development GO:0043588 220 0.114
organic cyclic compound catabolic process GO:1901361 295 0.113
regulation of secretion by cell GO:1903530 249 0.112
positive regulation of protein kinase activity GO:0045860 144 0.110
cell adhesion GO:0007155 329 0.108
Human Mouse
protein processing GO:0016485 163 0.107
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.107
regulation of neuron death GO:1901214 134 0.105
negative regulation of cellular component organization GO:0051129 194 0.105
Human
regulation of neurotransmitter levels GO:0001505 87 0.100
developmental cell growth GO:0048588 84 0.099
retina development in camera type eye GO:0060041 119 0.097
forebrain development GO:0030900 302 0.097
glycosyl compound catabolic process GO:1901658 206 0.097
negative regulation of cellular protein metabolic process GO:0032269 247 0.096
Human
regeneration GO:0031099 38 0.095
midgut development GO:0007494 4 0.094
cellular nitrogen compound catabolic process GO:0044270 280 0.094
regulation of hydrolase activity GO:0051336 246 0.093
Human
regulation of protein kinase activity GO:0045859 232 0.093
positive regulation of cell migration GO:0030335 109 0.090
Mouse
aromatic compound catabolic process GO:0019439 286 0.090
carbohydrate derivative catabolic process GO:1901136 231 0.089
nucleoside triphosphate metabolic process GO:0009141 230 0.089
positive regulation of cellular amine metabolic process GO:0033240 5 0.088
learning or memory GO:0007611 148 0.088
ribonucleoside catabolic process GO:0042454 206 0.088
hindbrain development GO:0030902 128 0.087
regulation of map kinase activity GO:0043405 120 0.086
positive regulation of secretion GO:0051047 130 0.086
positive regulation of neuron differentiation GO:0045666 141 0.086
microtubule cytoskeleton organization GO:0000226 157 0.082
inorganic cation transmembrane transport GO:0098662 207 0.081
single organism cell adhesion GO:0098602 156 0.081
ribonucleoside triphosphate metabolic process GO:0009199 220 0.081
lymphocyte differentiation GO:0030098 242 0.078
Mouse
regulation of axon diameter GO:0031133 6 0.077
regulation of cell activation GO:0050865 289 0.076
Mouse
gtp catabolic process GO:0006184 143 0.075
negative regulation of phosphorus metabolic process GO:0010563 184 0.073
transmission of nerve impulse GO:0019226 76 0.073
vesicle localization GO:0051648 86 0.073
protein modification by small protein conjugation or removal GO:0070647 207 0.073
epidermis development GO:0008544 187 0.073
heterocycle catabolic process GO:0046700 280 0.072
divalent metal ion transport GO:0070838 172 0.072
calcium ion transport GO:0006816 159 0.072
purine nucleoside triphosphate metabolic process GO:0009144 226 0.072
negative regulation of neuron projection development GO:0010977 50 0.072
Human
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.071
purine nucleotide metabolic process GO:0006163 302 0.071
nucleoside triphosphate catabolic process GO:0009143 205 0.070
histamine induced gastric acid secretion GO:0001697 1 0.070
central nervous system neuron differentiation GO:0021953 162 0.070
regulation of hormone levels GO:0010817 211 0.069
ameboidal type cell migration GO:0001667 128 0.069
negative regulation of intracellular signal transduction GO:1902532 167 0.069
Mouse
multicellular organismal signaling GO:0035637 91 0.069
hormone secretion GO:0046879 128 0.069
sensory organ morphogenesis GO:0090596 242 0.068
negative regulation of proteolysis GO:0045861 74 0.068
Human
regulation of anatomical structure size GO:0090066 178 0.068
ribonucleotide metabolic process GO:0009259 291 0.067
purine nucleoside metabolic process GO:0042278 241 0.067
wnt signaling pathway GO:0016055 188 0.067
peripheral nervous system development GO:0007422 53 0.067
negative regulation of nervous system development GO:0051961 156 0.066
Human
cellular chemical homeostasis GO:0055082 215 0.065
synaptic vesicle localization GO:0097479 59 0.065
regulation of gliogenesis GO:0014013 50 0.065
carbohydrate homeostasis GO:0033500 128 0.065
nucleoside metabolic process GO:0009116 246 0.065
nucleobase containing small molecule metabolic process GO:0055086 352 0.064
metencephalon development GO:0022037 89 0.064
peptidyl amino acid modification GO:0018193 336 0.064
Mouse
angiogenesis GO:0001525 201 0.063
purine nucleotide catabolic process GO:0006195 211 0.062
glial cell development GO:0021782 54 0.062
divalent inorganic cation transport GO:0072511 178 0.061
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.061
heart morphogenesis GO:0003007 178 0.061
purine nucleoside catabolic process GO:0006152 205 0.060
neuron migration GO:0001764 122 0.060
purine ribonucleotide metabolic process GO:0009150 290 0.060
regulation of cytokine production GO:0001817 266 0.059
Mouse
cellular response to monosaccharide stimulus GO:0071326 47 0.059
intracellular protein transport GO:0006886 204 0.059
Mouse
skeletal system development GO:0001501 356 0.059
pigmentation GO:0043473 71 0.059
regulation of cell size GO:0008361 72 0.059
endomembrane system organization GO:0010256 147 0.058
regulation of apoptotic signaling pathway GO:2001233 197 0.058
Mouse
regulation of metal ion transport GO:0010959 106 0.058
neuromuscular process controlling balance GO:0050885 59 0.058
negative regulation of phosphorylation GO:0042326 166 0.058
purine nucleoside triphosphate catabolic process GO:0009146 203 0.058
regulation of establishment of protein localization GO:0070201 181 0.057
regulation of protein maturation GO:1903317 96 0.057
Human
endocytosis GO:0006897 168 0.057
nucleotide metabolic process GO:0009117 332 0.057
nucleoside phosphate metabolic process GO:0006753 338 0.057
detection of stimulus involved in sensory perception GO:0050906 44 0.057
apoptotic signaling pathway GO:0097190 306 0.057
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.056
regulation of kinase activity GO:0043549 249 0.056
digestive system development GO:0055123 200 0.056
digestion GO:0007586 40 0.056
positive regulation of transferase activity GO:0051347 167 0.056
positive regulation of protein phosphorylation GO:0001934 242 0.055
Mouse
cation homeostasis GO:0055080 212 0.054
microtubule based process GO:0007017 236 0.054
ribonucleoside metabolic process GO:0009119 245 0.054
regulation of vesicle mediated transport GO:0060627 139 0.054
connective tissue development GO:0061448 179 0.054
protein maturation GO:0051604 176 0.053
Human
astrocyte differentiation GO:0048708 43 0.053
negative regulation of muscle contraction GO:0045932 12 0.053
learning GO:0007612 98 0.052
neurotransmitter secretion GO:0007269 62 0.052
negative regulation of protein metabolic process GO:0051248 282 0.052
Human
plasma membrane organization GO:0007009 90 0.052
negative regulation of cell projection organization GO:0031345 56 0.052
Human
skeletal system morphogenesis GO:0048705 203 0.052
myeloid leukocyte differentiation GO:0002573 119 0.052
telencephalon development GO:0021537 186 0.052
peptide hormone secretion GO:0030072 109 0.051
regulation of hormone secretion GO:0046883 88 0.051
regulation of organelle organization GO:0033043 289 0.051
establishment of organelle localization GO:0051656 122 0.050
negative regulation of cell proliferation GO:0008285 296 0.050
protein secretion GO:0009306 111 0.050
glucose homeostasis GO:0042593 128 0.050
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.049
negative regulation of hydrolase activity GO:0051346 71 0.049
Human
potassium ion transport GO:0006813 52 0.049
positive regulation of apoptotic process GO:0043065 217 0.049
neuron projection extension GO:1990138 64 0.049
positive regulation of cell motility GO:2000147 116 0.049
Mouse
regulation of neuronal synaptic plasticity GO:0048168 30 0.049
g protein coupled glutamate receptor signaling pathway GO:0007216 3 0.049
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.049
regulation of protein catabolic process GO:0042176 108 0.049
leukocyte differentiation GO:0002521 342 0.048
Mouse
response to organonitrogen compound GO:0010243 246 0.048
regulation of cell cycle GO:0051726 281 0.048
innervation GO:0060384 22 0.048
cognition GO:0050890 149 0.048
regulation of cellular catabolic process GO:0031329 242 0.048
epithelial cell proliferation GO:0050673 174 0.048
negative regulation of neuron death GO:1901215 98 0.048
positive regulation of cell death GO:0010942 224 0.048
detection of stimulus GO:0051606 84 0.047
organelle fission GO:0048285 170 0.047
chemotaxis GO:0006935 247 0.047
Mouse
regulation of protein localization GO:0032880 231 0.046
positive regulation of growth GO:0045927 104 0.045
regulation of response to wounding GO:1903034 189 0.045
purine containing compound metabolic process GO:0072521 311 0.045
glycosyl compound metabolic process GO:1901657 246 0.045
regulation of nucleotide metabolic process GO:0006140 169 0.044
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.044
nitrogen compound transport GO:0071705 271 0.044
neuron death GO:0070997 154 0.044
central nervous system neuron development GO:0021954 67 0.043
regulation of cell cycle process GO:0010564 160 0.043
response to steroid hormone GO:0048545 56 0.043
purine ribonucleoside metabolic process GO:0046128 241 0.043
negative regulation of protein phosphorylation GO:0001933 126 0.043
positive regulation of cell cycle process GO:0090068 61 0.043
ribonucleotide catabolic process GO:0009261 208 0.043
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.043
fat cell differentiation GO:0045444 160 0.042
sensory perception of sound GO:0007605 97 0.042
negative regulation of protein processing GO:0010955 79 0.042
Human
negative regulation of protein maturation GO:1903318 79 0.042
Human
metal ion homeostasis GO:0055065 189 0.042
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.042
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
t cell differentiation GO:0030217 174 0.042
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.042
regulation of proteolysis GO:0030162 164 0.042
Human
positive regulation of leukocyte differentiation GO:1902107 86 0.042
Mouse
regulation of t cell activation GO:0050863 170 0.042
Mouse
negative regulation of synapse assembly GO:0051964 3 0.042
positive regulation of synaptic plasticity GO:0031915 4 0.041
regulation of axon extension GO:0030516 43 0.041
nucleoside catabolic process GO:0009164 206 0.041
negative regulation of transferase activity GO:0051348 85 0.040
regulation of angiogenesis GO:0045765 81 0.040
purine ribonucleoside catabolic process GO:0046130 205 0.040
glial cell differentiation GO:0010001 131 0.040
protein catabolic process GO:0030163 221 0.040
blood vessel morphogenesis GO:0048514 285 0.040
regulation of postsynaptic membrane potential GO:0060078 48 0.040
regulation of cell migration GO:0030334 219 0.040
Mouse
second messenger mediated signaling GO:0019932 73 0.040
regulation of cellular response to stress GO:0080135 159 0.039
Mouse
positive regulation of organelle organization GO:0010638 128 0.039
nuclear division GO:0000280 158 0.039
cellular response to abiotic stimulus GO:0071214 56 0.039
membrane depolarization GO:0051899 64 0.039
regulation of exocytosis GO:0017157 61 0.039
regulation of protein processing GO:0070613 96 0.038
Human
oligodendrocyte differentiation GO:0048709 53 0.038
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.038
muscle cell differentiation GO:0042692 261 0.038
regulation of protein serine threonine kinase activity GO:0071900 157 0.038
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.038
cell growth GO:0016049 130 0.038
ribonucleoside triphosphate catabolic process GO:0009203 199 0.038
neuron projection guidance GO:0097485 141 0.038
negative regulation of immune system process GO:0002683 209 0.038
Mouse
peptide secretion GO:0002790 114 0.037
regulation of purine nucleotide metabolic process GO:1900542 169 0.037
regulation of cellular component biogenesis GO:0044087 181 0.037
sensory perception GO:0007600 245 0.037
regulation of camp metabolic process GO:0030814 30 0.037
regulation of vasculature development GO:1901342 88 0.036
regulation of feeding behavior GO:0060259 3 0.036
digestive tract development GO:0048565 190 0.036
ensheathment of neurons GO:0007272 76 0.036
sensory perception of light stimulus GO:0050953 54 0.036
protein localization to membrane GO:0072657 108 0.036
response to peptide GO:1901652 136 0.036
actin cytoskeleton organization GO:0030036 220 0.036
cell junction organization GO:0034330 77 0.036
positive regulation of nucleotide catabolic process GO:0030813 88 0.035
positive regulation of map kinase activity GO:0043406 84 0.035
ear development GO:0043583 200 0.035
negative regulation of cellular amine metabolic process GO:0033239 1 0.035
anatomical structure homeostasis GO:0060249 145 0.035
cell type specific apoptotic process GO:0097285 268 0.035
Mouse
anion transport GO:0006820 177 0.035
nucleotide catabolic process GO:0009166 217 0.035
myelination in peripheral nervous system GO:0022011 19 0.035
guanosine containing compound catabolic process GO:1901069 144 0.035
regulation of nucleoside metabolic process GO:0009118 130 0.035
regulation of protein transport GO:0051223 163 0.035
regulation of cell division GO:0051302 76 0.035
mating behavior GO:0007617 20 0.034
guanosine containing compound metabolic process GO:1901068 144 0.034
single organismal cell cell adhesion GO:0016337 131 0.034
organophosphate catabolic process GO:0046434 232 0.034
mating GO:0007618 27 0.034
ribose phosphate metabolic process GO:0019693 291 0.034
cerebellar cortex development GO:0021695 48 0.034
regulation of ossification GO:0030278 112 0.034
ras protein signal transduction GO:0007265 77 0.033
regulation of peptide transport GO:0090087 91 0.033
exocytosis GO:0006887 121 0.033
neurotransmitter transport GO:0006836 76 0.033
myotube differentiation GO:0014902 105 0.033
protein modification by small protein conjugation GO:0032446 187 0.033
cerebellum development GO:0021549 77 0.033
regulation of ion transmembrane transporter activity GO:0032412 54 0.033
cellular response to glucose stimulus GO:0071333 45 0.033
multicellular organismal homeostasis GO:0048871 164 0.033
establishment or maintenance of cell polarity GO:0007163 86 0.033
cell cell junction organization GO:0045216 72 0.033
axon cargo transport GO:0008088 33 0.032
myelination GO:0042552 74 0.032
germ cell development GO:0007281 185 0.032
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.032
response to transforming growth factor beta GO:0071559 88 0.032
skeletal muscle fiber development GO:0048741 58 0.032
organ growth GO:0035265 117 0.032
mesenchymal cell development GO:0014031 93 0.032
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.031
regulation of cell adhesion GO:0030155 154 0.031
Human Mouse
neuromuscular process GO:0050905 99 0.031
peripheral nervous system neuron axonogenesis GO:0048936 3 0.031
cellular glucose homeostasis GO:0001678 52 0.031
cellular response to temperature stimulus GO:0071502 2 0.031
response to light stimulus GO:0009416 135 0.031
rap protein signal transduction GO:0032486 3 0.031
regulation of purine nucleotide catabolic process GO:0033121 122 0.031
protein localization to organelle GO:0033365 185 0.031
response to nutrient levels GO:0031667 109 0.031
modification dependent protein catabolic process GO:0019941 133 0.031
action potential GO:0001508 78 0.031
divalent inorganic cation homeostasis GO:0072507 138 0.031
heart contraction GO:0060047 93 0.030
calcium ion homeostasis GO:0055074 127 0.030
positive regulation of ossification GO:0045778 47 0.030
schwann cell proliferation GO:0014010 2 0.030
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.030
wound healing GO:0042060 157 0.030
cellular response to organonitrogen compound GO:0071417 145 0.030
neural tube closure GO:0001843 90 0.030
extracellular structure organization GO:0043062 148 0.030
Mouse
regulation of tube size GO:0035150 57 0.030
cellular protein catabolic process GO:0044257 155 0.029
stem cell proliferation GO:0072089 117 0.029
purine ribonucleotide catabolic process GO:0009154 208 0.029
nucleotide biosynthetic process GO:0009165 78 0.029
positive regulation of fat cell differentiation GO:0045600 32 0.029
mitral valve development GO:0003174 4 0.029
response to organic cyclic compound GO:0014070 198 0.029
multicellular organism growth GO:0035264 161 0.029
hippocampus development GO:0021766 52 0.029
ossification GO:0001503 216 0.029
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.029
negative regulation of phosphate metabolic process GO:0045936 184 0.028
macromolecule catabolic process GO:0009057 281 0.028
neural retina development GO:0003407 41 0.028
respiratory tube development GO:0030323 167 0.028
somatostatin receptor signaling pathway GO:0038169 2 0.028
conditioned taste aversion GO:0001661 4 0.028
establishment of synaptic vesicle localization GO:0097480 57 0.028
anatomical structure maturation GO:0071695 49 0.028
response to monosaccharide GO:0034284 67 0.028
neuron apoptotic process GO:0051402 142 0.028
regulation of epithelial cell proliferation GO:0050678 141 0.028
regulation of multi organism process GO:0043900 111 0.028
regulation of neuron apoptotic process GO:0043523 122 0.028
spinal cord development GO:0021510 81 0.028
feeding behavior GO:0007631 62 0.028
positive regulation of gtpase activity GO:0043547 85 0.027
protein ubiquitination GO:0016567 171 0.027
regulation of nucleotide catabolic process GO:0030811 122 0.027
modification dependent macromolecule catabolic process GO:0043632 133 0.027
detection of light stimulus GO:0009583 25 0.027
gland development GO:0048732 330 0.027
regulation of leukocyte differentiation GO:1902105 159 0.027
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.027
spermatogenesis GO:0007283 284 0.027
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.027
Mouse
regulation of ion transmembrane transport GO:0034765 119 0.027
vesicle organization GO:0016050 60 0.027
regulation of cell projection size GO:0032536 6 0.027
multicellular organismal response to stress GO:0033555 62 0.027
regulation of neurotransmitter secretion GO:0046928 29 0.027
regulation of cellular protein catabolic process GO:1903362 61 0.027
axon guidance GO:0007411 141 0.027
cellular response to growth factor stimulus GO:0071363 197 0.027
cellular divalent inorganic cation homeostasis GO:0072503 127 0.026
forebrain generation of neurons GO:0021872 63 0.026
establishment of glial blood brain barrier GO:0060857 2 0.026
regulation of gtp catabolic process GO:0033124 113 0.026
organonitrogen compound biosynthetic process GO:1901566 192 0.026
camp metabolic process GO:0046058 40 0.026
pallium development GO:0021543 120 0.026
response to oxygen levels GO:0070482 62 0.026
photoreceptor cell development GO:0042461 40 0.026
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.026
regulation of cell growth GO:0001558 91 0.026
regulation of homeostatic process GO:0032844 182 0.026
Mouse
negative regulation of membrane potential GO:0045837 4 0.026
positive regulation of kinase activity GO:0033674 155 0.026
synaptic transmission glutamatergic GO:0035249 36 0.026
associative learning GO:0008306 61 0.026
cellular macromolecule catabolic process GO:0044265 206 0.026
striated muscle tissue development GO:0014706 293 0.025
cellular response to hexose stimulus GO:0071331 47 0.025
cervix development GO:0060067 2 0.025
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.025
immune effector process GO:0002252 321 0.025
Mouse
dendrite development GO:0016358 115 0.025
sensory perception of mechanical stimulus GO:0050954 107 0.025
regulation of neurotransmitter transport GO:0051588 35 0.025
positive regulation of peptide hormone secretion GO:0090277 31 0.025
ribose phosphate biosynthetic process GO:0046390 59 0.025
synaptic vesicle transport GO:0048489 57 0.025
cellular homeostasis GO:0019725 240 0.025
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.025
gtp metabolic process GO:0046039 144 0.025
regulation of protein complex assembly GO:0043254 83 0.025
neural precursor cell proliferation GO:0061351 121 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.025
cytokine production GO:0001816 319 0.024
Mouse
positive regulation of cellular component biogenesis GO:0044089 94 0.024
cytoskeleton dependent intracellular transport GO:0030705 50 0.024
protein autophosphorylation GO:0046777 61 0.024
positive regulation of cell cycle GO:0045787 92 0.024
regulation of defense response GO:0031347 233 0.024
eye photoreceptor cell development GO:0042462 31 0.024
mesoderm formation GO:0001707 62 0.024
proteasomal protein catabolic process GO:0010498 98 0.024
oxidation reduction process GO:0055114 342 0.024
urogenital system development GO:0001655 261 0.024
regulation of intestinal epithelial structure maintenance GO:0060730 1 0.024
lateral motor column neuron migration GO:0097477 3 0.024
b cell activation GO:0042113 161 0.024
regulation of fat cell differentiation GO:0045598 81 0.024
regulation of sodium ion transport GO:0002028 29 0.024
olfactory learning GO:0008355 2 0.024
gonad development GO:0008406 141 0.024
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.024
ubiquitin dependent protein catabolic process GO:0006511 129 0.024
positive regulation of schwann cell proliferation GO:0010625 1 0.024
catecholamine transport GO:0051937 21 0.024
regulation of endopeptidase activity GO:0052548 89 0.023
Human
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.023
regulation of ras protein signal transduction GO:0046578 114 0.023
axon ensheathment GO:0008366 76 0.023
cell junction assembly GO:0034329 52 0.023
negative regulation of apoptotic signaling pathway GO:2001234 104 0.023
Mouse
detection of external stimulus GO:0009581 61 0.023
negative regulation of reproductive process GO:2000242 31 0.023
cytosolic calcium ion homeostasis GO:0051480 70 0.023
body morphogenesis GO:0010171 45 0.023
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 3 0.023
optic nerve structural organization GO:0021633 2 0.023
cellular protein complex assembly GO:0043623 116 0.023
detection of abiotic stimulus GO:0009582 60 0.023
organonitrogen compound catabolic process GO:1901565 264 0.023
regulation of mapk cascade GO:0043408 248 0.023
Mouse
substrate independent telencephalic tangential migration GO:0021826 8 0.022
organophosphate biosynthetic process GO:0090407 122 0.022
thermosensory behavior GO:0040040 1 0.022
camera type eye photoreceptor cell differentiation GO:0060219 15 0.022
g protein coupled receptor internalization GO:0002031 3 0.022
epithelial to mesenchymal transition GO:0001837 47 0.022
positive regulation of gtp catabolic process GO:0033126 85 0.022
protein targeting GO:0006605 143 0.022
regulation of lymphocyte proliferation GO:0050670 117 0.022
developmental growth involved in morphogenesis GO:0060560 138 0.022
camp mediated signaling GO:0019933 15 0.022
establishment of endothelial blood brain barrier GO:0014045 3 0.022
intermediate filament bundle assembly GO:0045110 3 0.022
positive regulation of glial cell proliferation GO:0060252 4 0.022
mesenchyme development GO:0060485 152 0.022
hair follicle development GO:0001942 85 0.022
neuron maturation GO:0042551 29 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
hematopoietic progenitor cell differentiation GO:0002244 143 0.021
glutamate receptor signaling pathway GO:0007215 35 0.021
myeloid leukocyte activation GO:0002274 83 0.021
positive regulation of epithelial cell differentiation involved in kidney development GO:2000698 2 0.021
motor neuron migration GO:0097475 4 0.021
positive regulation of epithelial cell proliferation GO:0050679 68 0.021
lateral line system development GO:0048925 1 0.021
protein autoprocessing GO:0016540 2 0.021
paramesonephric duct development GO:0061205 3 0.021
negative regulation of peptidase activity GO:0010466 46 0.021
Human
regulation of heart contraction GO:0008016 77 0.021
negative regulation of leukocyte differentiation GO:1902106 51 0.021
Mouse
myoblast differentiation GO:0045445 52 0.021

Spock1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023