Mus musculus

0 known processes

Sprr2h

small proline-rich protein 2H

(Aliases: AI661967)

Sprr2h biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
striated muscle tissue development GO:0014706 293 0.187
positive regulation of cellular amine metabolic process GO:0033240 5 0.175
sensory perception GO:0007600 245 0.157
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.155
cell type specific apoptotic process GO:0097285 268 0.131
skeletal muscle fiber development GO:0048741 58 0.118
ion transmembrane transport GO:0034220 361 0.117
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.113
regulation of cellular amino acid metabolic process GO:0006521 5 0.110
regulation of systemic arterial blood pressure GO:0003073 61 0.108
defense response to other organism GO:0098542 197 0.104
blood circulation GO:0008015 195 0.103
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.102
amine metabolic process GO:0009308 45 0.102
g protein coupled receptor signaling pathway GO:0007186 243 0.100
regulation of skeletal muscle fiber development GO:0048742 36 0.100
regulation of cellular amine metabolic process GO:0033238 20 0.099
response to lipopolysaccharide GO:0032496 128 0.092
negative regulation of immune system process GO:0002683 209 0.088
immune effector process GO:0002252 321 0.088
anion transport GO:0006820 177 0.087
cellular amino acid metabolic process GO:0006520 103 0.087
cellular amine metabolic process GO:0044106 44 0.087
muscle fiber development GO:0048747 76 0.086
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.082
negative regulation of endothelial cell migration GO:0010596 4 0.082
potassium ion transmembrane transport GO:0071805 43 0.079
inorganic ion transmembrane transport GO:0098660 234 0.078
positive regulation of nervous system development GO:0051962 221 0.078
digestive tract development GO:0048565 190 0.076
regulation of blood pressure GO:0008217 93 0.074
negative regulation of multi organism process GO:0043901 68 0.073
developmental maturation GO:0021700 193 0.070
negative regulation of cell proliferation GO:0008285 296 0.070
muscle tissue development GO:0060537 308 0.070
organonitrogen compound biosynthetic process GO:1901566 192 0.069
protein maturation GO:0051604 176 0.069
cation homeostasis GO:0055080 212 0.066
myotube differentiation GO:0014902 105 0.065
multicellular organismal homeostasis GO:0048871 164 0.065
regulation of cellular ketone metabolic process GO:0010565 66 0.063
organic hydroxy compound metabolic process GO:1901615 203 0.063
defense response to gram positive bacterium GO:0050830 50 0.060
regulation of synaptic plasticity GO:0048167 87 0.059
negative regulation of nervous system development GO:0051961 156 0.059
regulation of hormone levels GO:0010817 211 0.059
cellular potassium ion transport GO:0071804 43 0.058
endocrine process GO:0050886 39 0.058
regulation of cytokine production GO:0001817 266 0.057
negative regulation of cellular protein metabolic process GO:0032269 247 0.056
regulation of defense response GO:0031347 233 0.055
positive regulation of cell death GO:0010942 224 0.055
circulatory system process GO:0003013 197 0.054
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.053
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.053
stem cell differentiation GO:0048863 268 0.051
response to molecule of bacterial origin GO:0002237 143 0.051
transmembrane transport GO:0055085 412 0.050
amino acid transport GO:0006865 61 0.049
synaptic transmission GO:0007268 329 0.049
regulation of angiotensin levels in blood GO:0002002 4 0.049
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.049
myotube cell development GO:0014904 60 0.049
leukocyte mediated cytotoxicity GO:0001909 62 0.048
positive regulation of cell migration GO:0030335 109 0.047
amide transport GO:0042886 138 0.047
camera type eye development GO:0043010 266 0.046
reflex GO:0060004 22 0.046
regulation of microvillus assembly GO:0032534 3 0.046
defense response to virus GO:0051607 68 0.045
hexose transport GO:0008645 56 0.045
negative regulation of molecular function GO:0044092 258 0.043
learning or memory GO:0007611 148 0.043
ear development GO:0043583 200 0.043
regulation of cell cycle GO:0051726 281 0.042
stem cell development GO:0048864 219 0.042
positive regulation of cytokine production GO:0001819 174 0.042
regulation of secretion by cell GO:1903530 249 0.040
interspecies interaction between organisms GO:0044419 83 0.040
leukocyte differentiation GO:0002521 342 0.040
regulation of t cell activation GO:0050863 170 0.040
negative regulation of hydrolase activity GO:0051346 71 0.039
negative regulation of muscle cell differentiation GO:0051148 33 0.039
regulation of kinase activity GO:0043549 249 0.039
intermediate filament organization GO:0045109 15 0.038
t cell differentiation GO:0030217 174 0.038
endomembrane system organization GO:0010256 147 0.038
blood vessel morphogenesis GO:0048514 285 0.038
regulation of angiotensin metabolic process GO:0060177 4 0.037
engulfment of apoptotic cell GO:0043652 3 0.037
gland development GO:0048732 330 0.037
cation transmembrane transport GO:0098655 266 0.037
membrane organization GO:0061024 245 0.036
carboxylic acid transport GO:0046942 100 0.036
regulation of protein transport GO:0051223 163 0.036
hindbrain development GO:0030902 128 0.035
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.035
muscle cell differentiation GO:0042692 261 0.035
potassium ion transport GO:0006813 52 0.035
regulation of mapk cascade GO:0043408 248 0.035
regulation of microvillus organization GO:0032530 3 0.035
myoblast differentiation GO:0045445 52 0.034
cellular ketone metabolic process GO:0042180 84 0.034
regulation of myotube differentiation GO:0010830 62 0.033
inorganic cation transmembrane transport GO:0098662 207 0.033
compound eye development GO:0048749 1 0.032
regulation of cell activation GO:0050865 289 0.032
leukocyte mediated immunity GO:0002443 174 0.032
inorganic anion transport GO:0015698 43 0.032
regulation of angiogenesis GO:0045765 81 0.032
regulation of renal sodium excretion GO:0035813 3 0.032
regulation of organelle organization GO:0033043 289 0.032
regulation of cellular response to oxidative stress GO:1900407 19 0.031
phenol containing compound metabolic process GO:0018958 60 0.031
limb development GO:0060173 166 0.031
carbohydrate transport GO:0008643 62 0.030
organic acid transport GO:0015849 101 0.030
regulation of protein localization GO:0032880 231 0.030
digestive system development GO:0055123 200 0.030
hormone secretion GO:0046879 128 0.029
macromolecule catabolic process GO:0009057 281 0.028
striated muscle cell development GO:0055002 125 0.028
negative regulation of phosphorus metabolic process GO:0010563 184 0.028
muscle cell development GO:0055001 133 0.028
peptidyl tyrosine modification GO:0018212 145 0.027
epithelium migration GO:0090132 63 0.027
epithelial cell proliferation GO:0050673 174 0.027
apoptotic signaling pathway GO:0097190 306 0.027
unsaturated fatty acid metabolic process GO:0033559 31 0.027
negative regulation of phosphate metabolic process GO:0045936 184 0.027
regulation of thyroid hormone generation GO:2000609 4 0.027
regulation of neural precursor cell proliferation GO:2000177 70 0.026
natural killer cell activation GO:0030101 44 0.026
regulation of hydrolase activity GO:0051336 246 0.026
regulation of leukocyte differentiation GO:1902105 159 0.026
protein processing GO:0016485 163 0.026
regulation of muscle tissue development GO:1901861 97 0.026
lymphocyte mediated immunity GO:0002449 139 0.025
tissue remodeling GO:0048771 102 0.025
positive regulation of cell projection organization GO:0031346 95 0.025
adult behavior GO:0030534 135 0.025
intermediate filament based process GO:0045103 27 0.025
cell maturation GO:0048469 127 0.025
response to oxygen levels GO:0070482 62 0.024
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.024
regulation of striated muscle cell differentiation GO:0051153 81 0.024
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.024
glucose transport GO:0015758 56 0.024
positive regulation of cell motility GO:2000147 116 0.024
negative regulation of cellular component organization GO:0051129 194 0.023
regulation of peptidase activity GO:0052547 96 0.023
cytokine production GO:0001816 319 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
regulation of transferase activity GO:0051338 263 0.023
dephosphorylation GO:0016311 129 0.023
cellular homeostasis GO:0019725 240 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
cellular lipid metabolic process GO:0044255 323 0.023
anion transmembrane transport GO:0098656 71 0.023
positive regulation of angiogenesis GO:0045766 46 0.023
anatomical structure homeostasis GO:0060249 145 0.023
response to corticosteroid GO:0031960 20 0.023
skeletal muscle organ development GO:0060538 163 0.022
organic anion transport GO:0015711 137 0.022
single organism cell adhesion GO:0098602 156 0.022
monosaccharide transport GO:0015749 58 0.022
regulation of lymphocyte differentiation GO:0045619 107 0.022
cell adhesion GO:0007155 329 0.022
negative regulation of cell activation GO:0050866 111 0.022
regulation of system process GO:0044057 200 0.022
bone development GO:0060348 120 0.022
innate immune response GO:0045087 157 0.022
single organismal cell cell adhesion GO:0016337 131 0.022
peptide transport GO:0015833 133 0.022
positive regulation of cell development GO:0010720 237 0.021
positive regulation of secretion GO:0051047 130 0.021
regulation of secretion GO:0051046 274 0.021
monovalent inorganic cation homeostasis GO:0055067 33 0.021
peptidyl amino acid modification GO:0018193 336 0.021
bone remodeling GO:0046849 53 0.021
defense response to bacterium GO:0042742 119 0.021
regulation of cell motility GO:2000145 236 0.021
regulation of innate immune response GO:0045088 91 0.020
phospholipid metabolic process GO:0006644 87 0.020
positive regulation of protein modification process GO:0031401 299 0.020
lymphocyte differentiation GO:0030098 242 0.020
negative regulation of lymphocyte activation GO:0051250 91 0.020
regulation of homeostatic process GO:0032844 182 0.020
cognition GO:0050890 149 0.020
regulation of t cell differentiation GO:0045580 83 0.020
angiogenesis GO:0001525 201 0.020
heart contraction GO:0060047 93 0.020
interleukin 13 secretion GO:0072611 2 0.019
sprouting angiogenesis GO:0002040 26 0.019
embryonic organ morphogenesis GO:0048562 276 0.019
tendon formation GO:0035992 4 0.019
hepatocyte apoptotic process GO:0097284 11 0.019
placenta development GO:0001890 140 0.019
cellular response to cytokine stimulus GO:0071345 189 0.019
muscle contraction GO:0006936 101 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
regulation of cell projection organization GO:0031344 206 0.018
locomotory behavior GO:0007626 195 0.018
t cell mediated cytotoxicity GO:0001913 26 0.018
regulation of protein kinase activity GO:0045859 232 0.018
interleukin 5 secretion GO:0072603 2 0.018
nitrogen compound transport GO:0071705 271 0.018
regulation of vesicle mediated transport GO:0060627 139 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
hair cycle GO:0042633 90 0.018
morphogenesis of a branching structure GO:0001763 203 0.018
production of molecular mediator of immune response GO:0002440 103 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
inflammatory response GO:0006954 244 0.017
cation transport GO:0006812 399 0.017
response to acid chemical GO:0001101 111 0.017
regulation of ossification GO:0030278 112 0.017
cardiac muscle tissue morphogenesis GO:0055008 44 0.017
regulation of ion transport GO:0043269 215 0.017
protein secretion GO:0009306 111 0.017
peptidyl tyrosine phosphorylation GO:0018108 143 0.017
regulation of vasculature development GO:1901342 88 0.017
regulation of cell migration GO:0030334 219 0.017
positive regulation of t cell activation GO:0050870 101 0.017
negative regulation of interleukin 5 secretion GO:2000663 1 0.017
stem cell proliferation GO:0072089 117 0.017
renal system process GO:0003014 48 0.017
negative regulation of interleukin 13 production GO:0032696 2 0.017
adult walking behavior GO:0007628 41 0.017
regulation of chromosome organization GO:0033044 83 0.017
protein localization to membrane GO:0072657 108 0.016
vascular process in circulatory system GO:0003018 62 0.016
jak stat cascade GO:0007259 42 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
amino acid transmembrane transport GO:0003333 37 0.016
regulation of blood vessel size GO:0050880 56 0.016
peptide metabolic process GO:0006518 46 0.016
ameboidal type cell migration GO:0001667 128 0.016
regulation of proteolysis GO:0030162 164 0.016
response to oxidative stress GO:0006979 123 0.016
response to organic cyclic compound GO:0014070 198 0.016
positive regulation of immune effector process GO:0002699 107 0.016
cellular amide metabolic process GO:0043603 58 0.015
tendon cell differentiation GO:0035990 4 0.015
blood vessel endothelial cell migration GO:0043534 23 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
regulation of neuron differentiation GO:0045664 281 0.015
negative regulation of neuron differentiation GO:0045665 101 0.015
response to decreased oxygen levels GO:0036293 59 0.015
learning GO:0007612 98 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
vasodilation GO:0042311 28 0.015
cytokine mediated signaling pathway GO:0019221 115 0.015
membrane invagination GO:0010324 17 0.015
cardiac chamber morphogenesis GO:0003206 93 0.015
epithelial cell development GO:0002064 159 0.015
regulation of neuron projection development GO:0010975 169 0.015
wnt signaling pathway GO:0016055 188 0.015
intermediate filament cytoskeleton organization GO:0045104 26 0.015
regulation of stem cell proliferation GO:0072091 78 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
cellular response to calcium ion GO:0071277 14 0.015
leukocyte apoptotic process GO:0071887 71 0.014
negative regulation of interleukin 13 secretion GO:2000666 1 0.014
neural precursor cell proliferation GO:0061351 121 0.014
response to peptide GO:1901652 136 0.014
negative regulation of myoblast differentiation GO:0045662 18 0.014
renal sodium excretion GO:0035812 3 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
negative regulation of cytokine production GO:0001818 84 0.014
regulation of multi organism process GO:0043900 111 0.014
regulation of transmembrane transport GO:0034762 128 0.014
regulation of organ morphogenesis GO:2000027 144 0.014
regulation of exit from mitosis GO:0007096 1 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
response to glucocorticoid GO:0051384 20 0.014
regulation of interleukin 13 secretion GO:2000665 2 0.014
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
phagocytosis GO:0006909 66 0.014
regulation of binding GO:0051098 111 0.014
adaptive immune response GO:0002250 155 0.014
peptide secretion GO:0002790 114 0.014
interaction with symbiont GO:0051702 14 0.014
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis GO:0060598 2 0.014
organelle fission GO:0048285 170 0.014
regulation of gliogenesis GO:0014013 50 0.014
nuclear division GO:0000280 158 0.014
cytokine metabolic process GO:0042107 71 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
cellular response to oxidative stress GO:0034599 76 0.013
regulation of membrane potential GO:0042391 192 0.013
cell killing GO:0001906 67 0.013
negative regulation of protein modification process GO:0031400 163 0.013
response to reactive oxygen species GO:0000302 56 0.013
actin cytoskeleton organization GO:0030036 220 0.013
regulation of interleukin 5 secretion GO:2000662 2 0.013
purine nucleotide biosynthetic process GO:0006164 65 0.013
regulation of neuron death GO:1901214 134 0.013
adult locomotory behavior GO:0008344 91 0.013
regulation of myoblast differentiation GO:0045661 29 0.013
negative regulation of inflammatory response GO:0050728 61 0.013
response to organonitrogen compound GO:0010243 246 0.013
positive regulation of homeostatic process GO:0032846 64 0.013
positive regulation of kinase activity GO:0033674 155 0.013
cell chemotaxis GO:0060326 81 0.013
epidermis development GO:0008544 187 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
regulation of glial cell differentiation GO:0045685 41 0.013
regulation of lymphocyte apoptotic process GO:0070228 41 0.013
sensory perception of mechanical stimulus GO:0050954 107 0.013
mapk cascade GO:0000165 281 0.013
positive regulation of transforming growth factor beta secretion GO:2001203 1 0.013
tissue homeostasis GO:0001894 115 0.013
mitotic cell cycle process GO:1903047 159 0.012
lymphocyte proliferation GO:0046651 164 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
regulation of interferon gamma production GO:0032649 57 0.012
response to tumor necrosis factor GO:0034612 26 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
corticotropin releasing hormone secretion GO:0043396 2 0.012
pattern recognition receptor signaling pathway GO:0002221 47 0.012
cell division GO:0051301 120 0.012
chloride transport GO:0006821 32 0.012
response to hydrogen peroxide GO:0042542 32 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
protein catabolic process GO:0030163 221 0.012
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.012
negative regulation of protein processing GO:0010955 79 0.012
second messenger mediated signaling GO:0019932 73 0.012
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.012
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
response to inorganic substance GO:0010035 96 0.012
gliogenesis GO:0042063 141 0.012
positive regulation of defense response GO:0031349 124 0.012
positive regulation of dopamine metabolic process GO:0045964 2 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
urogenital system development GO:0001655 261 0.012
positive regulation of keratinocyte proliferation GO:0010838 4 0.012
g protein coupled receptor internalization GO:0002031 3 0.012
regulation of peptide transport GO:0090087 91 0.012
endocytosis GO:0006897 168 0.012
keratinocyte differentiation GO:0030216 48 0.012
renal system development GO:0072001 225 0.012
fat cell differentiation GO:0045444 160 0.011
skeletal system development GO:0001501 356 0.011
keratinization GO:0031424 9 0.011
negative regulation of t cell activation GO:0050868 65 0.011
regulation of anion transport GO:0044070 27 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
blastocyst formation GO:0001825 33 0.011
regulation of myeloid cell differentiation GO:0045637 96 0.011
limb morphogenesis GO:0035108 149 0.011
negative regulation of glial cell differentiation GO:0045686 21 0.011
regulation of t cell proliferation GO:0042129 92 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
interferon gamma production GO:0032609 67 0.011
regulation of interleukin 1 alpha production GO:0032650 4 0.011
protein autoprocessing GO:0016540 2 0.011
response to hypoxia GO:0001666 58 0.011
negative regulation of leukocyte differentiation GO:1902106 51 0.011
antimicrobial peptide biosynthetic process GO:0002777 2 0.011
mesenchymal cell differentiation GO:0048762 107 0.011
lymphocyte apoptotic process GO:0070227 54 0.011
multicellular organismal response to stress GO:0033555 62 0.011
respiratory gaseous exchange GO:0007585 43 0.011
purine containing compound biosynthetic process GO:0072522 70 0.011
regulation of ph GO:0006885 26 0.011
positive regulation of organelle organization GO:0010638 128 0.011
sensory organ morphogenesis GO:0090596 242 0.011
odontogenesis of dentin containing tooth GO:0042475 66 0.011
negative regulation of vasculature development GO:1901343 26 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.011
oligopeptide transmembrane transport GO:0035672 4 0.011
disruption by host of symbiont cells GO:0051852 11 0.011
odontogenesis GO:0042476 78 0.011
negative regulation of proteolysis GO:0045861 74 0.011
formation of primary germ layer GO:0001704 77 0.011
positive regulation of stem cell proliferation GO:2000648 59 0.011
regulation of astrocyte differentiation GO:0048710 20 0.011
axonogenesis GO:0007409 274 0.011
calcium mediated signaling GO:0019722 46 0.011
negative regulation of myeloid cell differentiation GO:0045638 38 0.011
regulation of anatomical structure size GO:0090066 178 0.011
midgut development GO:0007494 4 0.011
peripheral nervous system development GO:0007422 53 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.010
regulation of corticotropin releasing hormone secretion GO:0043397 2 0.010
neutrophil mediated killing of bacterium GO:0070944 6 0.010
response to thyroid hormone GO:0097066 2 0.010
positive regulation of antimicrobial humoral response GO:0002760 2 0.010
metanephros development GO:0001656 79 0.010
positive regulation of leukocyte differentiation GO:1902107 86 0.010
t cell activation GO:0042110 289 0.010
negative regulation of response to oxidative stress GO:1902883 10 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010

Sprr2h disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.019
disease of anatomical entity DOID:7 0 0.019
eye and adnexa disease DOID:1492 0 0.019
nervous system disease DOID:863 0 0.019
eye disease DOID:5614 0 0.019