Mus musculus

0 known processes

Sqstm1

sequestosome 1

(Aliases: OSF-6,Osi,p62,STAP,A170)

Sqstm1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macroautophagy GO:0016236 21 0.999
Human
autophagy GO:0006914 45 0.997
Human
cellular response to starvation GO:0009267 57 0.941
Human
cellular response to nutrient levels GO:0031669 64 0.930
Human
positive regulation of macroautophagy GO:0016239 3 0.872
Human
response to extracellular stimulus GO:0009991 127 0.834
Human
amine metabolic process GO:0009308 45 0.773
regulation of cellular ketone metabolic process GO:0010565 66 0.745
negative regulation of intracellular signal transduction GO:1902532 167 0.732
regulation of cellular response to stress GO:0080135 159 0.730
Human
macromolecule catabolic process GO:0009057 281 0.701
protein modification by small protein conjugation GO:0032446 187 0.694
response to nutrient levels GO:0031667 109 0.684
Human
cellular response to external stimulus GO:0071496 88 0.673
Human
cellular homeostasis GO:0019725 240 0.667
development of primary sexual characteristics GO:0045137 143 0.662
cellular response to extracellular stimulus GO:0031668 81 0.650
Human
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.649
spermatogenesis GO:0007283 284 0.637
cerebellum development GO:0021549 77 0.627
cellular ketone metabolic process GO:0042180 84 0.619
response to starvation GO:0042594 65 0.581
Human
regulation of cellular amino acid metabolic process GO:0006521 5 0.570
male gamete generation GO:0048232 285 0.556
autophagic vacuole assembly GO:0000045 13 0.525
gonad development GO:0008406 141 0.515
mapk cascade GO:0000165 281 0.493
negative regulation of apoptotic signaling pathway GO:2001234 104 0.478
i kappab kinase nf kappab signaling GO:0007249 85 0.457
Human
protein catabolic process GO:0030163 221 0.456
cellular amino acid metabolic process GO:0006520 103 0.453
male genitalia morphogenesis GO:0048808 4 0.446
regulation of protein serine threonine kinase activity GO:0071900 157 0.444
central nervous system neuron differentiation GO:0021953 162 0.435
regulation of mapk cascade GO:0043408 248 0.411
cation homeostasis GO:0055080 212 0.410
protein modification by small protein conjugation or removal GO:0070647 207 0.387
germ cell development GO:0007281 185 0.386
vacuole organization GO:0007033 38 0.383
response to peptide GO:1901652 136 0.375
pyrimidine nucleobase metabolic process GO:0006206 3 0.367
regulation of apoptotic signaling pathway GO:2001233 197 0.362
response to molecule of bacterial origin GO:0002237 143 0.358
regulation of cellular amine metabolic process GO:0033238 20 0.355
epidermis development GO:0008544 187 0.349
apoptotic signaling pathway GO:0097190 306 0.348
protein ubiquitination GO:0016567 171 0.337
ubiquitin dependent protein catabolic process GO:0006511 129 0.324
cellular response to cytokine stimulus GO:0071345 189 0.324
response to organonitrogen compound GO:0010243 246 0.321
ras protein signal transduction GO:0007265 77 0.320
regulation of protein kinase activity GO:0045859 232 0.316
response to organic cyclic compound GO:0014070 198 0.303
metal ion homeostasis GO:0055065 189 0.303
regulation of cellular catabolic process GO:0031329 242 0.300
Human
stress activated mapk cascade GO:0051403 80 0.297
male sex differentiation GO:0046661 109 0.295
cellular response to lipopolysaccharide GO:0071222 77 0.290
cellular amine metabolic process GO:0044106 44 0.280
negative regulation of cellular component organization GO:0051129 194 0.274
microtubule based process GO:0007017 236 0.267
positive regulation of mapk cascade GO:0043410 170 0.249
small molecule catabolic process GO:0044282 71 0.247
positive regulation of cellular amine metabolic process GO:0033240 5 0.240
cellular response to oxidative stress GO:0034599 76 0.233
response to peptide hormone GO:0043434 127 0.228
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.226
protein targeting GO:0006605 143 0.224
negative regulation of transposition GO:0010529 2 0.223
small gtpase mediated signal transduction GO:0007264 97 0.223
protein kinase b signaling GO:0043491 74 0.219
protein maturation GO:0051604 176 0.215
cellular response to biotic stimulus GO:0071216 92 0.213
defense response to other organism GO:0098542 197 0.210
locomotory behavior GO:0007626 195 0.210
oxidation reduction process GO:0055114 342 0.209
regulation of peptidase activity GO:0052547 96 0.202
negative regulation of molecular function GO:0044092 258 0.199
ossification GO:0001503 216 0.199
dna metabolic process GO:0006259 303 0.199
placenta development GO:0001890 140 0.197
response to epidermal growth factor GO:0070849 4 0.197
monocarboxylic acid catabolic process GO:0072329 27 0.195
glucose homeostasis GO:0042593 128 0.193
cell junction maintenance GO:0034331 4 0.193
cellular lipid catabolic process GO:0044242 52 0.191
response to growth factor GO:0070848 198 0.189
adult walking behavior GO:0007628 41 0.187
response to reactive oxygen species GO:0000302 56 0.187
monosaccharide transport GO:0015749 58 0.181
response to interleukin 4 GO:0070670 23 0.180
male anatomical structure morphogenesis GO:0090598 4 0.180
microtubule cytoskeleton organization GO:0000226 157 0.178
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.176
central nervous system neuron development GO:0021954 67 0.175
protein acylation GO:0043543 64 0.173
organelle assembly GO:0070925 177 0.168
response to oxidative stress GO:0006979 123 0.166
cellular response to molecule of bacterial origin GO:0071219 83 0.163
cellular response to organonitrogen compound GO:0071417 145 0.158
metencephalon development GO:0022037 89 0.156
adult behavior GO:0030534 135 0.154
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.152
negative regulation of neuron death GO:1901215 98 0.147
cellular lipid metabolic process GO:0044255 323 0.144
cellular response to arsenic containing substance GO:0071243 4 0.142
anatomical structure homeostasis GO:0060249 145 0.139
fatty acid oxidation GO:0019395 28 0.138
homeostasis of number of cells GO:0048872 210 0.138
skeletal system development GO:0001501 356 0.137
organic acid catabolic process GO:0016054 51 0.137
cellular response to cadmium ion GO:0071276 3 0.134
regulation of autophagy GO:0010506 30 0.134
Human
negative regulation of cellular protein metabolic process GO:0032269 247 0.133
male gonad development GO:0008584 88 0.132
cellular protein catabolic process GO:0044257 155 0.132
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.130
immune response regulating signaling pathway GO:0002764 125 0.127
cellular metal ion homeostasis GO:0006875 151 0.126
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.126
cellular response to granulocyte macrophage colony stimulating factor stimulus GO:0097011 3 0.125
oogenesis GO:0048477 56 0.125
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.125
intrinsic apoptotic signaling pathway GO:0097193 132 0.124
fatty acid metabolic process GO:0006631 121 0.124
female gamete generation GO:0007292 74 0.122
cellular response to growth factor stimulus GO:0071363 197 0.121
regulation of protein localization GO:0032880 231 0.120
cell type specific apoptotic process GO:0097285 268 0.119
negative regulation of protein modification process GO:0031400 163 0.119
response to alcohol GO:0097305 48 0.118
peptidyl amino acid modification GO:0018193 336 0.115
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.113
regulation of response to wounding GO:1903034 189 0.112
lipid homeostasis GO:0055088 63 0.111
regulation of binding GO:0051098 111 0.111
cellular chemical homeostasis GO:0055082 215 0.110
positive regulation of proteolysis GO:0045862 85 0.109
adherens junction maintenance GO:0034334 1 0.109
regulation of multi organism process GO:0043900 111 0.107
mitochondrion degradation GO:0000422 3 0.107
regulation of transferase activity GO:0051338 263 0.105
modification dependent macromolecule catabolic process GO:0043632 133 0.105
spermatid differentiation GO:0048515 115 0.104
meiotic nuclear division GO:0007126 115 0.104
multicellular organismal homeostasis GO:0048871 164 0.103
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.103
glucose import GO:0046323 32 0.102
negative regulation of osteoblast differentiation GO:0045668 30 0.102
forebrain neuron development GO:0021884 30 0.102
response to endoplasmic reticulum stress GO:0034976 53 0.099
positive regulation of autophagy GO:0010508 9 0.099
Human
response to lipopolysaccharide GO:0032496 128 0.099
regulation of epidermal cell differentiation GO:0045604 21 0.098
negative regulation of proteolysis GO:0045861 74 0.098
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.098
biomineral tissue development GO:0031214 64 0.098
cerebellar cortex development GO:0021695 48 0.097
protein processing GO:0016485 163 0.094
connective tissue development GO:0061448 179 0.094
negative regulation of phosphorus metabolic process GO:0010563 184 0.092
nuclear import GO:0051170 95 0.091
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.091
cellular response to interleukin 4 GO:0071353 21 0.089
skin development GO:0043588 220 0.088
negative regulation of ossification GO:0030279 49 0.088
regulation of proteolysis GO:0030162 164 0.087
regulation of hydrolase activity GO:0051336 246 0.087
cell maturation GO:0048469 127 0.087
single organism nuclear import GO:1902593 95 0.086
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.086
carbohydrate transport GO:0008643 62 0.085
immune response activating signal transduction GO:0002757 116 0.085
lipid modification GO:0030258 65 0.085
response to inorganic substance GO:0010035 96 0.084
regulation of anatomical structure size GO:0090066 178 0.082
immune effector process GO:0002252 321 0.082
mitochondrion organization GO:0007005 134 0.081
positive regulation of protein modification process GO:0031401 299 0.081
Rat
meiotic cell cycle GO:0051321 122 0.080
genitalia development GO:0048806 37 0.080
cellular carbohydrate metabolic process GO:0044262 119 0.080
negative regulation of protein metabolic process GO:0051248 282 0.079
cytokine production GO:0001816 319 0.079
regulation of kinase activity GO:0043549 249 0.078
cellular ion homeostasis GO:0006873 165 0.078
axonogenesis GO:0007409 274 0.077
cellular response to peptide GO:1901653 92 0.077
regulation of neuron apoptotic process GO:0043523 122 0.076
positive regulation of cell death GO:0010942 224 0.075
regulation of stress activated mapk cascade GO:0032872 69 0.075
developmental maturation GO:0021700 193 0.074
peptidyl lysine modification GO:0018205 77 0.073
development of primary male sexual characteristics GO:0046546 88 0.072
lipid catabolic process GO:0016042 69 0.072
fatty acid catabolic process GO:0009062 25 0.072
labyrinthine layer blood vessel development GO:0060716 21 0.071
myelination in peripheral nervous system GO:0022011 19 0.071
genitalia morphogenesis GO:0035112 11 0.070
cytoplasmic transport GO:0016482 234 0.070
labyrinthine layer development GO:0060711 49 0.070
maintenance of location GO:0051235 89 0.070
protein autophosphorylation GO:0046777 61 0.069
hexose transport GO:0008645 56 0.068
positive regulation of protein phosphorylation GO:0001934 242 0.067
Rat
response to metal ion GO:0010038 47 0.067
regulation of macroautophagy GO:0016241 12 0.067
Human
reactive oxygen species metabolic process GO:0072593 84 0.066
regulation of defense response GO:0031347 233 0.065
multicellular organismal aging GO:0010259 24 0.065
interleukin 1 mediated signaling pathway GO:0070498 4 0.064
acylglycerol homeostasis GO:0055090 16 0.064
carbohydrate homeostasis GO:0033500 128 0.064
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.062
negative regulation of cellular amine metabolic process GO:0033239 1 0.061
mammary gland epithelium development GO:0061180 65 0.061
reactive nitrogen species metabolic process GO:2001057 0 0.061
organelle fission GO:0048285 170 0.061
leukocyte differentiation GO:0002521 342 0.061
cerebellum morphogenesis GO:0021587 42 0.060
cellular response to lipid GO:0071396 145 0.060
negative regulation of cell proliferation GO:0008285 296 0.060
innate immune response GO:0045087 157 0.060
positive regulation of response to wounding GO:1903036 66 0.060
regulation of endopeptidase activity GO:0052548 89 0.059
negative regulation of phosphorylation GO:0042326 166 0.059
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.059
endomembrane system organization GO:0010256 147 0.059
camera type eye development GO:0043010 266 0.058
cellular response to inorganic substance GO:0071241 37 0.058
forebrain neuron differentiation GO:0021879 52 0.058
regulation of neuron death GO:1901214 134 0.058
neuron apoptotic process GO:0051402 142 0.057
regulation of body fluid levels GO:0050878 162 0.056
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.056
regulation of peptidyl lysine acetylation GO:2000756 22 0.055
hexose biosynthetic process GO:0019319 39 0.054
negative regulation of protein phosphorylation GO:0001933 126 0.054
response to topologically incorrect protein GO:0035966 25 0.054
modification dependent protein catabolic process GO:0019941 133 0.054
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.054
tissue homeostasis GO:0001894 115 0.054
regulation of protein catabolic process GO:0042176 108 0.054
fatty acid beta oxidation GO:0006635 16 0.053
adult locomotory behavior GO:0008344 91 0.053
regulation of proteasomal protein catabolic process GO:0061136 46 0.053
positive regulation of myeloid cell apoptotic process GO:0033034 4 0.053
membrane organization GO:0061024 245 0.053
negative regulation of transcription from rna polymerase ii promoter in response to stress GO:0097201 1 0.052
positive regulation of protein export from nucleus GO:0046827 4 0.052
internal protein amino acid acetylation GO:0006475 42 0.052
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.051
protein import GO:0017038 101 0.051
intracellular protein transport GO:0006886 204 0.050
negative regulation of protein processing GO:0010955 79 0.050
glial cell differentiation GO:0010001 131 0.049
gland development GO:0048732 330 0.049
chromatin modification GO:0016568 187 0.049
spermatid development GO:0007286 108 0.049
interspecies interaction between organisms GO:0044419 83 0.049
response to inactivity GO:0014854 4 0.048
gliogenesis GO:0042063 141 0.048
positive regulation of apoptotic process GO:0043065 217 0.047
mitochondrial dna metabolic process GO:0032042 13 0.047
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.047
establishment of protein localization to organelle GO:0072594 118 0.047
peptidyl lysine acetylation GO:0018394 45 0.046
nucleocytoplasmic transport GO:0006913 139 0.046
multicellular organism growth GO:0035264 161 0.046
regulation of organelle organization GO:0033043 289 0.046
epithelial cell proliferation GO:0050673 174 0.045
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 8 0.045
muscle tissue development GO:0060537 308 0.044
regulation of cysteine type endopeptidase activity GO:2000116 65 0.044
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.044
embryonic placenta development GO:0001892 98 0.044
regulation of wound healing GO:0061041 40 0.044
regulation of epidermis development GO:0045682 33 0.043
regulation of protein maturation GO:1903317 96 0.043
negative regulation of neuron apoptotic process GO:0043524 92 0.043
negative regulation of peptidase activity GO:0010466 46 0.043
positive regulation of protein catabolic process GO:0045732 60 0.043
regulation of protein binding GO:0043393 60 0.043
regulation of dna templated transcription in response to stress GO:0043620 9 0.042
regulation of cell cycle GO:0051726 281 0.042
t cell activation GO:0042110 289 0.042
erk1 and erk2 cascade GO:0070371 77 0.042
cerebellar cortex formation GO:0021697 22 0.042
wound healing GO:0042060 157 0.041
cellular response to hormone stimulus GO:0032870 150 0.041
regulation of translation GO:0006417 71 0.041
divalent metal ion transport GO:0070838 172 0.041
regulation of bone mineralization GO:0030500 31 0.041
cellular transition metal ion homeostasis GO:0046916 32 0.040
regulation of intracellular protein transport GO:0033157 82 0.040
positive regulation of endopeptidase activity GO:0010950 43 0.040
sensory organ morphogenesis GO:0090596 242 0.039
carboxylic acid catabolic process GO:0046395 51 0.039
cerebellar granular layer development GO:0021681 13 0.039
regulation of protein ubiquitination GO:0031396 52 0.039
cation transport GO:0006812 399 0.039
stress activated protein kinase signaling cascade GO:0031098 81 0.038
regulation of cellular protein catabolic process GO:1903362 61 0.038
regulation of nucleocytoplasmic transport GO:0046822 73 0.038
mitochondrial genome maintenance GO:0000002 15 0.038
forebrain generation of neurons GO:0021872 63 0.038
regulation of cytokine production GO:0001817 266 0.038
positive regulation of necrotic cell death GO:0010940 1 0.038
bone mineralization GO:0030282 54 0.038
extracellular structure organization GO:0043062 148 0.038
cellular response to organic cyclic compound GO:0071407 87 0.037
negative regulation of hydrolase activity GO:0051346 71 0.037
regulation of response to oxidative stress GO:1902882 19 0.037
regulation of cytoplasmic transport GO:1903649 112 0.037
regulation of reactive oxygen species metabolic process GO:2000377 40 0.037
response to hydrogen peroxide GO:0042542 32 0.037
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.037
negative regulation of cellular catabolic process GO:0031330 47 0.037
regulation of ossification GO:0030278 112 0.037
homeostasis of number of cells within a tissue GO:0048873 25 0.037
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.036
triglyceride homeostasis GO:0070328 15 0.036
regulation of cellular response to oxidative stress GO:1900407 19 0.036
cellular response to dna damage stimulus GO:0006974 207 0.036
posttranscriptional regulation of gene expression GO:0010608 155 0.036
regulation of secretion GO:0051046 274 0.036
meiosis i GO:0007127 60 0.036
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.036
glucose transport GO:0015758 56 0.035
positive regulation of protein kinase activity GO:0045860 144 0.035
peripheral nervous system development GO:0007422 53 0.035
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.035
g protein coupled receptor signaling pathway GO:0007186 243 0.035
multicellular organismal signaling GO:0035637 91 0.035
regulation of protein transport GO:0051223 163 0.035
circadian rhythm GO:0007623 114 0.035
attachment of spindle microtubules to kinetochore GO:0008608 4 0.035
t cell receptor signaling pathway GO:0050852 46 0.034
negative regulation of binding GO:0051100 39 0.034
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.034
regulation of cytokine biosynthetic process GO:0042035 59 0.034
positive regulation of cytokine production GO:0001819 174 0.034
regulation of transposition GO:0010528 2 0.033
negative regulation of dna binding GO:0043392 20 0.033
cellular macromolecule catabolic process GO:0044265 206 0.033
cholesterol storage GO:0010878 4 0.033
monocarboxylic acid metabolic process GO:0032787 191 0.033
fertilization GO:0009566 127 0.033
cartilage development GO:0051216 140 0.033
positive regulation of wound healing GO:0090303 17 0.032
positive regulation of growth GO:0045927 104 0.032
positive regulation of leukocyte apoptotic process GO:2000108 21 0.032
proteasomal protein catabolic process GO:0010498 98 0.032
regulation of cell growth GO:0001558 91 0.032
myeloid cell differentiation GO:0030099 233 0.031
regulation of response to biotic stimulus GO:0002831 38 0.031
positive regulation of cellular protein catabolic process GO:1903364 34 0.031
regulation of protein processing GO:0070613 96 0.031
positive regulation of cell cycle GO:0045787 92 0.031
cytokine biosynthetic process GO:0042089 68 0.031
regulation of cellular component size GO:0032535 121 0.031
negative regulation of phosphate metabolic process GO:0045936 184 0.031
calcium ion transport GO:0006816 159 0.030
reactive oxygen species biosynthetic process GO:1903409 8 0.030
negative regulation of transferase activity GO:0051348 85 0.030
phagocytosis GO:0006909 66 0.030
signal transduction in absence of ligand GO:0038034 55 0.030
lateral inhibition GO:0046331 1 0.030
copper ion homeostasis GO:0055070 9 0.030
pole plasm assembly GO:0007315 2 0.029
dendrite development GO:0016358 115 0.029
response to muscle inactivity involved in regulation of muscle adaptation GO:0014877 4 0.029
peptidyl tyrosine modification GO:0018212 145 0.029
defense response to gram positive bacterium GO:0050830 50 0.029
sensory system development GO:0048880 3 0.029
regulation of osteoblast differentiation GO:0045667 67 0.029
regulation of cell cycle process GO:0010564 160 0.029
icosanoid metabolic process GO:0006690 33 0.029
cerebellar granular layer morphogenesis GO:0021683 10 0.029
organic hydroxy compound metabolic process GO:1901615 203 0.028
response to monosaccharide GO:0034284 67 0.028
fatty acid derivative metabolic process GO:1901568 33 0.028
cellular glucose homeostasis GO:0001678 52 0.028
antigen receptor mediated signaling pathway GO:0050851 64 0.028
defense response to bacterium GO:0042742 119 0.028
myeloid cell homeostasis GO:0002262 114 0.028
cellular amide metabolic process GO:0043603 58 0.028
regulation of system process GO:0044057 200 0.028
negative regulation of defense response GO:0031348 77 0.028
lateral line system development GO:0048925 1 0.028
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.027
negative regulation of organelle organization GO:0010639 90 0.027
meiotic cell cycle process GO:1903046 77 0.027
cell differentiation in hindbrain GO:0021533 24 0.027
regulation of carbohydrate biosynthetic process GO:0043255 40 0.027
lymphocyte differentiation GO:0030098 242 0.027
positive regulation of map kinase activity GO:0043406 84 0.026
alpha amino acid metabolic process GO:1901605 59 0.026
sequestering of metal ion GO:0051238 19 0.026
regulation of cell migration GO:0030334 219 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.026
positive regulation of kinase activity GO:0033674 155 0.026
fat cell differentiation GO:0045444 160 0.026
negative regulation of cytokine production GO:0001818 84 0.026
striated muscle tissue development GO:0014706 293 0.026
response to oxygen levels GO:0070482 62 0.026
activation of immune response GO:0002253 138 0.026
regulation of biomineral tissue development GO:0070167 33 0.025
response to radiation GO:0009314 165 0.025
male meiosis GO:0007140 37 0.025
negative regulation of protein transport GO:0051224 46 0.025
positive regulation of transferase activity GO:0051347 167 0.025
chromatin organization GO:0006325 206 0.025
translation GO:0006412 93 0.025
cellular response to abiotic stimulus GO:0071214 56 0.025
regulation of protein acetylation GO:1901983 22 0.025
cellular divalent inorganic cation homeostasis GO:0072503 127 0.025
regulation of cellular response to growth factor stimulus GO:0090287 82 0.025
body fluid secretion GO:0007589 53 0.025
purine ribonucleoside metabolic process GO:0046128 241 0.025
extracellular matrix organization GO:0030198 147 0.025
determination of adult lifespan GO:0008340 11 0.025
regulation of erk1 and erk2 cascade GO:0070372 71 0.025
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.025
regulation of actin nucleation GO:0051125 4 0.025
protein localization to organelle GO:0033365 185 0.024
transition metal ion homeostasis GO:0055076 54 0.024
negative regulation of protein maturation GO:1903318 79 0.024
divalent inorganic cation transport GO:0072511 178 0.024
protein oligomerization GO:0051259 67 0.024
Rat
female gonad development GO:0008585 71 0.024
alcohol metabolic process GO:0006066 116 0.024
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.024
neuron projection regeneration GO:0031102 14 0.024
response to acid chemical GO:0001101 111 0.024
renal system development GO:0072001 225 0.024
regulation of fat cell differentiation GO:0045598 81 0.024
kidney epithelium development GO:0072073 121 0.024
cellular iron ion homeostasis GO:0006879 16 0.024
cellular alcohol metabolic process GO:0044107 3 0.023
lipid localization GO:0010876 126 0.023
regulation of mucus secretion GO:0070255 11 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.023
positive regulation of cell growth GO:0030307 33 0.023
sensory perception of pain GO:0019233 47 0.023
nuclear transport GO:0051169 139 0.023
action potential GO:0001508 78 0.023
response to ethanol GO:0045471 18 0.023
response to dsrna GO:0043331 30 0.023
interleukin 8 production GO:0032637 4 0.023
developmental growth involved in morphogenesis GO:0060560 138 0.023
response to muscle inactivity GO:0014870 4 0.023
regulation of cytoskeleton organization GO:0051493 122 0.023
oocyte development GO:0048599 33 0.022
cellular response to peptide hormone stimulus GO:0071375 92 0.022
muscle contraction GO:0006936 101 0.022
lens development in camera type eye GO:0002088 62 0.022
cell cycle switching GO:0060184 1 0.022
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.022
negative regulation of immune system process GO:0002683 209 0.022
receptor internalization GO:0031623 16 0.022
sensory perception GO:0007600 245 0.022
regulation of ras protein signal transduction GO:0046578 114 0.022
protein export from nucleus GO:0006611 20 0.022
neuronal action potential GO:0019228 54 0.022
lipoprotein metabolic process GO:0042157 43 0.022
regulation of mitotic cell cycle GO:0007346 126 0.022
divalent inorganic cation homeostasis GO:0072507 138 0.021
regulation of dna binding GO:0051101 39 0.021
fibrinolysis GO:0042730 3 0.021
regulation of neuron differentiation GO:0045664 281 0.021
cellular copper ion homeostasis GO:0006878 8 0.021
transmission of nerve impulse GO:0019226 76 0.021
organic hydroxy compound biosynthetic process GO:1901617 77 0.021
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.020
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.020
response to unfolded protein GO:0006986 21 0.020
rna processing GO:0006396 105 0.020
regulation of generation of precursor metabolites and energy GO:0043467 38 0.020
regulation of hormone levels GO:0010817 211 0.020
actomyosin structure organization GO:0031032 56 0.020
regulation of meiotic cell cycle GO:0051445 34 0.020
cytokine metabolic process GO:0042107 71 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.020
negative regulation of macroautophagy GO:0016242 5 0.020
regulation of peptidyl threonine phosphorylation GO:0010799 12 0.020
regulation of cellular component biogenesis GO:0044087 181 0.020
regulation of blood coagulation GO:0030193 28 0.020

Sqstm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 0 0.209
disease of anatomical entity DOID:7 0 0.209
Human
nervous system disease DOID:863 0 0.209
neuropathy DOID:870 0 0.209
disease of metabolism DOID:0014667 0 0.103
central nervous system disease DOID:331 0 0.099
charcot marie tooth disease DOID:10595 0 0.096
neurodegenerative disease DOID:1289 0 0.041
inherited metabolic disorder DOID:655 0 0.024
cardiovascular system disease DOID:1287 0 0.022