Mus musculus

41 known processes

Srsf2

serine/arginine-rich splicing factor 2

(Aliases: MRF-1,SC35,Sfrs2,D11Wsu175e,Sfrs10,Pr264)

Srsf2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.953
mrna metabolic process GO:0016071 84 0.831
mrna splicing via spliceosome GO:0000398 43 0.821
rna processing GO:0006396 105 0.770
nuclear division GO:0000280 158 0.748
Worm
regulation of rna splicing GO:0043484 37 0.730
mitotic cell cycle GO:0000278 195 0.699
rna splicing GO:0008380 54 0.693
mrna processing GO:0006397 63 0.681
alternative mrna splicing via spliceosome GO:0000380 12 0.646
oocyte anterior posterior axis specification GO:0007314 2 0.599
regulation of mrna splicing via spliceosome GO:0048024 32 0.570
mitotic cell cycle process GO:1903047 159 0.540
rna transport GO:0050658 18 0.449
organelle fission GO:0048285 170 0.416
Worm
rna splicing via transesterification reactions GO:0000375 43 0.402
oocyte construction GO:0007308 2 0.371
regulation of mrna processing GO:0050684 41 0.368
methylation GO:0032259 134 0.360
germ cell development GO:0007281 185 0.358
regulation of cell cycle process GO:0010564 160 0.350
Worm
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.340
male meiosis i GO:0007141 16 0.316
regulation of mrna stability GO:0043488 23 0.309
positive regulation of rna splicing GO:0033120 12 0.303
posttranscriptional regulation of gene expression GO:0010608 155 0.293
male gamete generation GO:0048232 285 0.286
pole plasm assembly GO:0007315 2 0.280
negative regulation of mrna processing GO:0050686 12 0.280
rna localization GO:0006403 23 0.279
negative regulation of mrna splicing via spliceosome GO:0048025 12 0.273
nucleic acid transport GO:0050657 18 0.271
negative regulation of rna splicing GO:0033119 12 0.251
regulation of mrna metabolic process GO:1903311 43 0.243
oogenesis GO:0048477 56 0.223
regulation of mitotic cell cycle GO:0007346 126 0.216
establishment of rna localization GO:0051236 18 0.211
meiotic nuclear division GO:0007126 115 0.202
Worm
microtubule based process GO:0007017 236 0.201
positive regulation of mrna splicing via spliceosome GO:0048026 11 0.197
negative regulation of mrna metabolic process GO:1903312 13 0.192
regulation of cell cycle GO:0051726 281 0.191
Worm
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.189
regulation of alternative mrna splicing via spliceosome GO:0000381 8 0.189
compound eye development GO:0048749 1 0.188
intracellular mrna localization GO:0008298 4 0.176
microtubule cytoskeleton organization GO:0000226 157 0.166
spermatogenesis GO:0007283 284 0.153
oocyte axis specification GO:0007309 2 0.149
nuclear export GO:0051168 34 0.146
regulation of organelle organization GO:0033043 289 0.146
Worm
cellular response to dna damage stimulus GO:0006974 207 0.144
regionalization GO:0003002 337 0.139
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.139
translation GO:0006412 93 0.139
segmentation GO:0035282 93 0.122
negative regulation of cellular component organization GO:0051129 194 0.117
positive regulation of cell cycle process GO:0090068 61 0.115
adult locomotory behavior GO:0008344 91 0.113
nitrogen compound transport GO:0071705 271 0.108
nucleocytoplasmic transport GO:0006913 139 0.106
cytoplasmic transport GO:0016482 234 0.104
female gamete generation GO:0007292 74 0.103
protein methylation GO:0006479 81 0.101
positive regulation of mrna metabolic process GO:1903313 17 0.100
posttranscriptional gene silencing by rna GO:0035194 10 0.098
positive regulation of mrna processing GO:0050685 16 0.097
rna interference GO:0016246 2 0.095
protein complex disassembly GO:0043241 40 0.095
negative regulation of dna templated transcription termination GO:0060567 1 0.093
ossification GO:0001503 216 0.086
regulation of translation GO:0006417 71 0.085
adult behavior GO:0030534 135 0.085
spermatid differentiation GO:0048515 115 0.085
mitotic nuclear division GO:0007067 48 0.081
regulation of mitotic cell cycle phase transition GO:1901990 73 0.081
gene silencing GO:0016458 38 0.080
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.072
regulation of cellular component biogenesis GO:0044087 181 0.072
regulation of rna stability GO:0043487 26 0.072
male meiosis GO:0007140 37 0.068
organonitrogen compound biosynthetic process GO:1901566 192 0.067
positive regulation of dna templated transcription elongation GO:0032786 2 0.064
dna repair GO:0006281 107 0.064
gonad development GO:0008406 141 0.063
oocyte development GO:0048599 33 0.062
cellular response to cytokine stimulus GO:0071345 189 0.061
nls bearing protein import into nucleus GO:0006607 2 0.061
positive regulation of translation GO:0045727 19 0.060
negative regulation of cell cycle GO:0045786 123 0.060
regulation of cell division GO:0051302 76 0.060
Worm
skin development GO:0043588 220 0.059
negative regulation of keratinocyte differentiation GO:0045617 4 0.059
protein desumoylation GO:0016926 2 0.057
locomotory behavior GO:0007626 195 0.054
dna templated transcription termination GO:0006353 4 0.054
regulation of binding GO:0051098 111 0.054
apoptotic signaling pathway GO:0097190 306 0.054
positive regulation of cell cycle GO:0045787 92 0.052
regulation of nuclear division GO:0051783 56 0.051
Worm
spliceosomal complex assembly GO:0000245 6 0.050
regulation of apoptotic signaling pathway GO:2001233 197 0.050
ribonucleoprotein complex subunit organization GO:0071826 28 0.049
spermatid development GO:0007286 108 0.049
nucleobase containing compound transport GO:0015931 27 0.049
protein import into nucleus GO:0006606 95 0.047
oocyte differentiation GO:0009994 35 0.047
transcription coupled nucleotide excision repair GO:0006283 2 0.047
oxidation reduction process GO:0055114 342 0.047
mrna catabolic process GO:0006402 22 0.046
regulation of cell cycle phase transition GO:1901987 77 0.046
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.045
ribonucleoprotein complex localization GO:0071166 1 0.045
positive regulation of organelle organization GO:0010638 128 0.045
3 utr mediated mrna stabilization GO:0070935 2 0.045
stem cell differentiation GO:0048863 268 0.044
negative regulation of protein metabolic process GO:0051248 282 0.044
cell fate specification GO:0001708 72 0.043
macromolecule methylation GO:0043414 120 0.041
nuclear transcribed mrna catabolic process GO:0000956 16 0.040
ribonucleoprotein complex disassembly GO:0032988 3 0.040
stem cell development GO:0048864 219 0.040
regulation of circadian rhythm GO:0042752 58 0.040
hematopoietic progenitor cell differentiation GO:0002244 143 0.039
lung development GO:0030324 164 0.039
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.038
meiotic cell cycle GO:0051321 122 0.038
Worm
protein alkylation GO:0008213 81 0.036
nuclear transport GO:0051169 139 0.036
dna metabolic process GO:0006259 303 0.036
mrna stabilization GO:0048255 9 0.036
maternal process involved in female pregnancy GO:0060135 32 0.035
amine metabolic process GO:0009308 45 0.035
negative regulation of cellular protein metabolic process GO:0032269 247 0.035
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.035
positive regulation of programmed cell death GO:0043068 218 0.034
centrosome separation GO:0051299 4 0.034
mrna localization resulting in posttranscriptional regulation of gene expression GO:0010609 2 0.034
regulation of keratinocyte proliferation GO:0010837 15 0.034
striated muscle contraction GO:0006941 45 0.033
regulation of glycogen catabolic process GO:0005981 2 0.033
gene silencing by rna GO:0031047 19 0.033
positive regulation of cell cycle phase transition GO:1901989 17 0.032
small molecule biosynthetic process GO:0044283 132 0.032
ras protein signal transduction GO:0007265 77 0.031
maternal placenta development GO:0001893 20 0.031
dna templated transcription elongation GO:0006354 13 0.031
hexose metabolic process GO:0019318 98 0.031
rna 3 end processing GO:0031123 20 0.031
epidermis development GO:0008544 187 0.030
cellular amine metabolic process GO:0044106 44 0.030
carbohydrate derivative biosynthetic process GO:1901137 183 0.030
inflammatory response GO:0006954 244 0.029
cellular macromolecule catabolic process GO:0044265 206 0.029
nucleus organization GO:0006997 45 0.028
skeletal system development GO:0001501 356 0.028
modification dependent macromolecule catabolic process GO:0043632 133 0.028
cell maturation GO:0048469 127 0.027
stem cell maintenance GO:0019827 130 0.027
cellular amino acid metabolic process GO:0006520 103 0.027
embryonic skeletal system development GO:0048706 120 0.027
sensory perception GO:0007600 245 0.026
regulation of protein complex assembly GO:0043254 83 0.026
positive regulation of cell death GO:0010942 224 0.025
placenta development GO:0001890 140 0.025
rna stabilization GO:0043489 9 0.025
circulatory system process GO:0003013 197 0.025
regulation of intracellular transport GO:0032386 159 0.024
positive regulation of mitotic cell cycle GO:0045931 41 0.024
response to lipopolysaccharide GO:0032496 128 0.024
dna integrity checkpoint GO:0031570 28 0.024
intrinsic apoptotic signaling pathway GO:0097193 132 0.024
regulation of proteolysis GO:0030162 164 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
positive regulation of apoptotic process GO:0043065 217 0.023
pharynx development GO:0060465 1 0.023
regulation of dna templated transcription termination GO:0031554 1 0.023
negative regulation of translation GO:0017148 22 0.023
organophosphate biosynthetic process GO:0090407 122 0.023
germ cell proliferation GO:0036093 7 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.022
epithelial to mesenchymal transition GO:0001837 47 0.022
histone methylation GO:0016571 71 0.022
protein localization to organelle GO:0033365 185 0.022
nuclear import GO:0051170 95 0.022
mrna export from nucleus GO:0006406 11 0.022
mrna transport GO:0051028 13 0.022
wound healing GO:0042060 157 0.022
dna recombination GO:0006310 92 0.022
epithelial cell proliferation GO:0050673 174 0.021
axon target recognition GO:0007412 4 0.021
regulation of transferase activity GO:0051338 263 0.021
negative regulation of molecular function GO:0044092 258 0.021
embryonic axis specification GO:0000578 30 0.021
regulation of microtubule based process GO:0032886 52 0.021
lipid biosynthetic process GO:0008610 179 0.020
peptidyl amino acid modification GO:0018193 336 0.020
response to oxidative stress GO:0006979 123 0.020
blood vessel morphogenesis GO:0048514 285 0.020
spindle organization GO:0007051 28 0.020
heart morphogenesis GO:0003007 178 0.020
response to organic cyclic compound GO:0014070 198 0.020
multi multicellular organism process GO:0044706 109 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.020
circadian rhythm GO:0007623 114 0.020
transcription elongation from rna polymerase ii promoter GO:0006368 9 0.020
cell cycle checkpoint GO:0000075 47 0.020
chromatin modification GO:0016568 187 0.020
regulation of protein localization GO:0032880 231 0.019
termination of rna polymerase ii transcription GO:0006369 1 0.019
cellular protein complex assembly GO:0043623 116 0.019
regulation of cell activation GO:0050865 289 0.019
regulation of cellular response to stress GO:0080135 159 0.019
meiotic cell cycle process GO:1903046 77 0.019
negative regulation of apoptotic cell clearance GO:2000426 1 0.019
fatty acid biosynthetic process GO:0006633 41 0.019
single organism nuclear import GO:1902593 95 0.019
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.018
leukocyte proliferation GO:0070661 172 0.018
transmembrane transport GO:0055085 412 0.018
development of primary sexual characteristics GO:0045137 143 0.018
regulation of protein catabolic process GO:0042176 108 0.018
nuclear mrna surveillance GO:0071028 1 0.017
regulation of cytoskeleton organization GO:0051493 122 0.017
g1 s transition of mitotic cell cycle GO:0000082 57 0.017
protein targeting GO:0006605 143 0.017
body morphogenesis GO:0010171 45 0.017
Worm
cellular protein complex disassembly GO:0043624 36 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
positive regulation of nervous system development GO:0051962 221 0.017
positive regulation of proteolysis GO:0045862 85 0.017
cartilage development GO:0051216 140 0.016
developmental maturation GO:0021700 193 0.016
development of primary male sexual characteristics GO:0046546 88 0.016
response to interferon gamma GO:0034341 34 0.016
macromolecule catabolic process GO:0009057 281 0.016
negative regulation of protein complex disassembly GO:0043242 22 0.016
histone modification GO:0016570 159 0.016
metaphase plate congression GO:0051310 2 0.016
heterocycle catabolic process GO:0046700 280 0.016
mesenchymal cell differentiation GO:0048762 107 0.016
epithelial cell proliferation involved in lung morphogenesis GO:0060502 5 0.016
skeletal system morphogenesis GO:0048705 203 0.016
respiratory system development GO:0060541 190 0.016
negative regulation of cell cycle process GO:0010948 69 0.016
molting cycle GO:0042303 90 0.015
cellular response to organic cyclic compound GO:0071407 87 0.015
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.015
regulation of response to dna damage stimulus GO:2001020 34 0.015
cardiac muscle contraction GO:0060048 32 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
lung morphogenesis GO:0060425 50 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
glycosyl compound biosynthetic process GO:1901659 21 0.015
mrna splice site selection GO:0006376 5 0.015
neuroblast differentiation GO:0014016 2 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
innate immune response GO:0045087 157 0.014
establishment of organelle localization GO:0051656 122 0.014
connective tissue development GO:0061448 179 0.014
aromatic compound catabolic process GO:0019439 286 0.014
negative regulation of phagocytosis GO:0050765 4 0.014
cellularization GO:0007349 1 0.014
cellular lipid metabolic process GO:0044255 323 0.014
regulation of reproductive process GO:2000241 66 0.014
angiogenesis GO:0001525 201 0.014
urogenital system development GO:0001655 261 0.014
positive regulation of protein modification process GO:0031401 299 0.014
blood circulation GO:0008015 195 0.013
polyamine biosynthetic process GO:0006596 2 0.013
histone h3 k4 methylation GO:0051568 23 0.013
positive regulation of cellular amine metabolic process GO:0033240 5 0.013
negative regulation of cell development GO:0010721 169 0.013
regulation of protein complex disassembly GO:0043244 28 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
muscle system process GO:0003012 141 0.013
ribonucleoside biosynthetic process GO:0042455 21 0.013
cell division GO:0051301 120 0.013
Worm
intracellular protein transport GO:0006886 204 0.013
cellular response to lipid GO:0071396 145 0.013
fatty acid metabolic process GO:0006631 121 0.012
negative regulation of dna replication GO:0008156 4 0.012
positive regulation of glycogen catabolic process GO:0045819 2 0.012
regulation of organ morphogenesis GO:2000027 144 0.012
nucleotide excision repair GO:0006289 13 0.012
glucan metabolic process GO:0044042 32 0.012
leukocyte differentiation GO:0002521 342 0.012
carbohydrate metabolic process GO:0005975 230 0.012
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.012
regulation of multi organism process GO:0043900 111 0.012
negative regulation of neuron projection regeneration GO:0070571 3 0.012
rna dependent dna replication GO:0006278 3 0.012
cellular protein catabolic process GO:0044257 155 0.012
respiratory tube development GO:0030323 167 0.012
humoral immune response GO:0006959 57 0.012
organic acid biosynthetic process GO:0016053 86 0.012
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 1 0.012
positive regulation of multi organism process GO:0043902 26 0.011
response to temperature stimulus GO:0009266 55 0.011
b cell activation GO:0042113 161 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
protein localization to chromosome centromeric region GO:0071459 1 0.011
mesenchyme development GO:0060485 152 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
negative regulation of dna dependent dna replication GO:2000104 1 0.011
visual perception GO:0007601 52 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
regulation of keratinocyte differentiation GO:0045616 11 0.011
positive regulation of reproductive process GO:2000243 19 0.011
regulation of carbohydrate metabolic process GO:0006109 75 0.011
tripartite regional subdivision GO:0007351 9 0.011
negative regulation of mitotic cell cycle GO:0045930 58 0.011
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.011
cellular ketone metabolic process GO:0042180 84 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.010
epithelial cell proliferation involved in prostate gland development GO:0060767 11 0.010
rna catabolic process GO:0006401 29 0.010
digestive tract morphogenesis GO:0048546 147 0.010
cellular polysaccharide metabolic process GO:0044264 38 0.010
regulation of endopeptidase activity GO:0052548 89 0.010
regulation of response to wounding GO:1903034 189 0.010
regulation of b cell activation GO:0050864 81 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
organonitrogen compound catabolic process GO:1901565 264 0.010
heart contraction GO:0060047 93 0.010

Srsf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.062
disease of anatomical entity DOID:7 0 0.062
nervous system disease DOID:863 0 0.062
neurodegenerative disease DOID:1289 0 0.023
myopathy DOID:423 0 0.018
muscular disease DOID:0080000 0 0.018
musculoskeletal system disease DOID:17 0 0.018
muscle tissue disease DOID:66 0 0.018