Mus musculus

8 known processes

Srxn1

sulfiredoxin 1 homolog (S. cerevisiae)

(Aliases: TX01,AW488194,AI854065,1700127B04Rik,Npn3,Srx,Srx1)

Srxn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.313
oxidation reduction process GO:0055114 342 0.129
glutathione metabolic process GO:0006749 16 0.099
cellular amide metabolic process GO:0043603 58 0.089
cellular lipid metabolic process GO:0044255 323 0.081
peptide metabolic process GO:0006518 46 0.077
response to oxidative stress GO:0006979 123 0.075
cellular modified amino acid metabolic process GO:0006575 63 0.075
sulfur compound metabolic process GO:0006790 100 0.067
apoptotic signaling pathway GO:0097190 306 0.063
cation transport GO:0006812 399 0.059
male gamete generation GO:0048232 285 0.057
cellular ketone metabolic process GO:0042180 84 0.055
amine metabolic process GO:0009308 45 0.052
negative regulation of cellular protein metabolic process GO:0032269 247 0.052
cellular amine metabolic process GO:0044106 44 0.047
negative regulation of protein metabolic process GO:0051248 282 0.046
regulation of cellular amine metabolic process GO:0033238 20 0.045
spermatogenesis GO:0007283 284 0.042
protein modification by small protein conjugation GO:0032446 187 0.041
regulation of cellular amino acid metabolic process GO:0006521 5 0.041
macromolecule catabolic process GO:0009057 281 0.040
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
negative regulation of intracellular signal transduction GO:1902532 167 0.039
negative regulation of protein modification process GO:0031400 163 0.037
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
regulation of cytokine production GO:0001817 266 0.034
transmembrane transport GO:0055085 412 0.034
response to inorganic substance GO:0010035 96 0.033
positive regulation of cell death GO:0010942 224 0.033
positive regulation of protein phosphorylation GO:0001934 242 0.033
alpha amino acid metabolic process GO:1901605 59 0.032
regulation of transferase activity GO:0051338 263 0.032
protein modification by small protein conjugation or removal GO:0070647 207 0.031
cytokine production GO:0001816 319 0.031
glycerolipid metabolic process GO:0046486 122 0.031
inflammatory response GO:0006954 244 0.031
monocarboxylic acid metabolic process GO:0032787 191 0.031
nucleoside phosphate metabolic process GO:0006753 338 0.029
regulation of cellular ketone metabolic process GO:0010565 66 0.029
cellular homeostasis GO:0019725 240 0.029
response to extracellular stimulus GO:0009991 127 0.029
regulation of apoptotic signaling pathway GO:2001233 197 0.028
organonitrogen compound catabolic process GO:1901565 264 0.028
ion transmembrane transport GO:0034220 361 0.028
organic cyclic compound catabolic process GO:1901361 295 0.028
positive regulation of protein modification process GO:0031401 299 0.028
serine family amino acid metabolic process GO:0009069 7 0.028
cofactor metabolic process GO:0051186 80 0.027
cytoplasmic transport GO:0016482 234 0.027
response to organic cyclic compound GO:0014070 198 0.027
organic anion transport GO:0015711 137 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.026
cellular ion homeostasis GO:0006873 165 0.026
response to reactive oxygen species GO:0000302 56 0.026
selenium compound metabolic process GO:0001887 3 0.026
intracellular protein transport GO:0006886 204 0.026
nitrogen compound transport GO:0071705 271 0.026
peptidyl amino acid modification GO:0018193 336 0.026
reactive oxygen species metabolic process GO:0072593 84 0.026
regulation of membrane potential GO:0042391 192 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
cellular macromolecule catabolic process GO:0044265 206 0.026
chemotaxis GO:0006935 247 0.025
regulation of mapk cascade GO:0043408 248 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.025
negative regulation of protein phosphorylation GO:0001933 126 0.025
organic acid transport GO:0015849 101 0.025
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.024
maintenance of location GO:0051235 89 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.024
sensory perception GO:0007600 245 0.024
cation transmembrane transport GO:0098655 266 0.024
aromatic compound catabolic process GO:0019439 286 0.024
skeletal system development GO:0001501 356 0.024
negative regulation of molecular function GO:0044092 258 0.023
mapk cascade GO:0000165 281 0.023
cell adhesion GO:0007155 329 0.023
locomotory behavior GO:0007626 195 0.023
divalent metal ion transport GO:0070838 172 0.022
placenta development GO:0001890 140 0.022
membrane organization GO:0061024 245 0.022
dephosphorylation GO:0016311 129 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
nucleotide metabolic process GO:0009117 332 0.022
regulation of protein serine threonine kinase activity GO:0071900 157 0.022
regulation of organelle organization GO:0033043 289 0.021
wound healing GO:0042060 157 0.021
regulation of defense response GO:0031347 233 0.021
carboxylic acid biosynthetic process GO:0046394 86 0.021
regulation of reactive oxygen species metabolic process GO:2000377 40 0.021
cellular protein catabolic process GO:0044257 155 0.021
adult behavior GO:0030534 135 0.021
response to oxygen levels GO:0070482 62 0.021
fertilization GO:0009566 127 0.021
muscle cell differentiation GO:0042692 261 0.021
small molecule biosynthetic process GO:0044283 132 0.021
modification dependent protein catabolic process GO:0019941 133 0.021
cellular metal ion homeostasis GO:0006875 151 0.021
fatty acid metabolic process GO:0006631 121 0.021
regulation of kinase activity GO:0043549 249 0.020
negative regulation of cellular amine metabolic process GO:0033239 1 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
protein catabolic process GO:0030163 221 0.020
response to nutrient levels GO:0031667 109 0.020
regulation of cell activation GO:0050865 289 0.020
cellular chemical homeostasis GO:0055082 215 0.020
cellular amino acid biosynthetic process GO:0008652 22 0.020
microtubule based process GO:0007017 236 0.020
regulation of cell cycle GO:0051726 281 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
cellular response to dna damage stimulus GO:0006974 207 0.020
retrograde transport endosome to golgi GO:0042147 2 0.019
compound eye development GO:0048749 1 0.019
carboxylic acid transport GO:0046942 100 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
protein ubiquitination GO:0016567 171 0.019
divalent inorganic cation homeostasis GO:0072507 138 0.019
nucleoside metabolic process GO:0009116 246 0.019
regulation of ion transport GO:0043269 215 0.019
blood circulation GO:0008015 195 0.019
regulation of hormone levels GO:0010817 211 0.019
lipid biosynthetic process GO:0008610 179 0.019
protein targeting GO:0006605 143 0.019
lipid transport GO:0006869 98 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
kidney development GO:0001822 213 0.019
response to organonitrogen compound GO:0010243 246 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
cell type specific apoptotic process GO:0097285 268 0.019
organic acid biosynthetic process GO:0016053 86 0.019
positive regulation of macroautophagy GO:0016239 3 0.019
regulation of secretion GO:0051046 274 0.018
response to acid chemical GO:0001101 111 0.018
coenzyme metabolic process GO:0006732 52 0.018
metal ion homeostasis GO:0055065 189 0.018
dna metabolic process GO:0006259 303 0.018
regulation of cellular response to stress GO:0080135 159 0.018
cellular response to lipid GO:0071396 145 0.018
extracellular matrix organization GO:0030198 147 0.018
ear development GO:0043583 200 0.018
cation homeostasis GO:0055080 212 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
positive regulation of necrotic cell death GO:0010940 1 0.018
organophosphate catabolic process GO:0046434 232 0.018
muscle tissue development GO:0060537 308 0.018
blood vessel morphogenesis GO:0048514 285 0.018
spermatid differentiation GO:0048515 115 0.018
sequestering of calcium ion GO:0051208 18 0.018
anion transport GO:0006820 177 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
t cell activation GO:0042110 289 0.018
protein oligomerization GO:0051259 67 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
sequestering of metal ion GO:0051238 19 0.017
regulation of protein kinase activity GO:0045859 232 0.017
divalent inorganic cation transport GO:0072511 178 0.017
endomembrane system organization GO:0010256 147 0.017
myeloid cell differentiation GO:0030099 233 0.017
defense response to other organism GO:0098542 197 0.017
regulation of protein localization GO:0032880 231 0.017
glycoprotein metabolic process GO:0009100 116 0.017
cellular response to oxidative stress GO:0034599 76 0.017
reactive nitrogen species metabolic process GO:2001057 0 0.017
leukocyte migration GO:0050900 124 0.017
protein maturation GO:0051604 176 0.017
germ cell development GO:0007281 185 0.017
digestive system development GO:0055123 200 0.017
muscle contraction GO:0006936 101 0.017
regulation of cell motility GO:2000145 236 0.017
synaptic transmission GO:0007268 329 0.016
regulation of homeostatic process GO:0032844 182 0.016
glycerophospholipid metabolic process GO:0006650 71 0.016
axonogenesis GO:0007409 274 0.016
circulatory system process GO:0003013 197 0.016
sensory organ morphogenesis GO:0090596 242 0.016
negative regulation of transferase activity GO:0051348 85 0.016
cell chemotaxis GO:0060326 81 0.016
ras protein signal transduction GO:0007265 77 0.016
cellular response to inorganic substance GO:0071241 37 0.016
exocytosis GO:0006887 121 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
nonribosomal peptide biosynthetic process GO:0019184 5 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
spermatid development GO:0007286 108 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
heterocycle catabolic process GO:0046700 280 0.016
positive regulation of cell development GO:0010720 237 0.016
renal system development GO:0072001 225 0.016
sulfur compound biosynthetic process GO:0044272 37 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016
response to peptide hormone GO:0043434 127 0.016
multi multicellular organism process GO:0044706 109 0.016
lipid localization GO:0010876 126 0.016
regulation of response to wounding GO:1903034 189 0.016
single organism cell adhesion GO:0098602 156 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
regulation of establishment of protein localization GO:0070201 181 0.015
cellular response to external stimulus GO:0071496 88 0.015
steroid metabolic process GO:0008202 119 0.015
protein localization to organelle GO:0033365 185 0.015
mitochondrion organization GO:0007005 134 0.015
muscle system process GO:0003012 141 0.015
proteasomal protein catabolic process GO:0010498 98 0.015
actin cytoskeleton organization GO:0030036 220 0.015
organelle localization GO:0051640 179 0.015
fat cell differentiation GO:0045444 160 0.015
phospholipid metabolic process GO:0006644 87 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
cell substrate adhesion GO:0031589 130 0.015
regulation of cell adhesion GO:0030155 154 0.015
purine containing compound metabolic process GO:0072521 311 0.015
cellular response to arsenic containing substance GO:0071243 4 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
microtubule cytoskeleton organization GO:0000226 157 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
purine containing compound catabolic process GO:0072523 213 0.015
engulfment of apoptotic cell GO:0043652 3 0.015
regulation of cell migration GO:0030334 219 0.015
skeletal muscle organ development GO:0060538 163 0.015
response to peptide GO:1901652 136 0.015
response to radiation GO:0009314 165 0.015
gland development GO:0048732 330 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
regulation of secretion by cell GO:1903530 249 0.015
immune effector process GO:0002252 321 0.015
homeostasis of number of cells GO:0048872 210 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
second messenger mediated signaling GO:0019932 73 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
leukocyte differentiation GO:0002521 342 0.014
carbohydrate metabolic process GO:0005975 230 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
regulation of cellular component size GO:0032535 121 0.014
regulation of protein transport GO:0051223 163 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
protein processing GO:0016485 163 0.014
neuronal action potential GO:0019228 54 0.014
small molecule catabolic process GO:0044282 71 0.014
oocyte construction GO:0007308 2 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
camera type eye development GO:0043010 266 0.014
regionalization GO:0003002 337 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
positive regulation of nervous system development GO:0051962 221 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
lipoprotein metabolic process GO:0042157 43 0.014
positive regulation of organelle organization GO:0010638 128 0.014
regulation of map kinase activity GO:0043405 120 0.014
regulation of body fluid levels GO:0050878 162 0.013
extracellular structure organization GO:0043062 148 0.013
oocyte axis specification GO:0007309 2 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
substantia nigra development GO:0021762 2 0.013
lipid modification GO:0030258 65 0.013
cellular calcium ion homeostasis GO:0006874 119 0.013
rho protein signal transduction GO:0007266 32 0.013
organelle assembly GO:0070925 177 0.013
multicellular organismal signaling GO:0035637 91 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
cellular protein complex assembly GO:0043623 116 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
regulation of inflammatory response GO:0050727 147 0.013
muscle cell development GO:0055001 133 0.013
innate immune response GO:0045087 157 0.013
cognition GO:0050890 149 0.013
response to endoplasmic reticulum stress GO:0034976 53 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
calcium ion transport GO:0006816 159 0.013
positive regulation of homeostatic process GO:0032846 64 0.013
transition metal ion transport GO:0000041 38 0.013
amide transport GO:0042886 138 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
signal transduction by p53 class mediator GO:0072331 51 0.013
regulation of multi organism process GO:0043900 111 0.013
regulation of system process GO:0044057 200 0.013
response to lipopolysaccharide GO:0032496 128 0.013
regulation of proteolysis GO:0030162 164 0.013
negative regulation of proteolysis GO:0045861 74 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
regulation of transmembrane transport GO:0034762 128 0.013
striated muscle tissue development GO:0014706 293 0.013
calcium ion homeostasis GO:0055074 127 0.013
organic hydroxy compound transport GO:0015850 93 0.013
regulation of cytoskeleton organization GO:0051493 122 0.012
negative regulation of immune system process GO:0002683 209 0.012
peptide transport GO:0015833 133 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
striated muscle cell development GO:0055002 125 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
nuclear transport GO:0051169 139 0.012
hormone secretion GO:0046879 128 0.012
response to vitamin a GO:0033189 1 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
regulation of protein catabolic process GO:0042176 108 0.012
cellular response to peptide hormone stimulus GO:0071375 92 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
lateral inhibition GO:0046331 1 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
developmental maturation GO:0021700 193 0.012
alcohol metabolic process GO:0006066 116 0.012
regulation of cell cycle process GO:0010564 160 0.012
action potential GO:0001508 78 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
leukocyte mediated immunity GO:0002443 174 0.012
regulation of hydrolase activity GO:0051336 246 0.012
dendritic spine maintenance GO:0097062 4 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
endocytosis GO:0006897 168 0.012
forebrain development GO:0030900 302 0.012
negative regulation of protein processing GO:0010955 79 0.012
ossification GO:0001503 216 0.012
cell growth GO:0016049 130 0.012
epithelial cell development GO:0002064 159 0.012
positive regulation of cell activation GO:0050867 158 0.012
positive regulation of secretion GO:0051047 130 0.012
lipid catabolic process GO:0016042 69 0.012
l amino acid transport GO:0015807 32 0.012
regulation of protein maturation GO:1903317 96 0.012
protein import GO:0017038 101 0.011
regulation of peptidase activity GO:0052547 96 0.011
amino acid transmembrane transport GO:0003333 37 0.011
response to ischemia GO:0002931 14 0.011
leukocyte chemotaxis GO:0030595 69 0.011
cytokine biosynthetic process GO:0042089 68 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
organelle fission GO:0048285 170 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
myeloid cell homeostasis GO:0002262 114 0.011
actin filament organization GO:0007015 113 0.011
regulation of protein processing GO:0070613 96 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
amino acid transport GO:0006865 61 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
angiogenesis GO:0001525 201 0.011
leukocyte proliferation GO:0070661 172 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
glial cell differentiation GO:0010001 131 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
cytokine metabolic process GO:0042107 71 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.011
plasma membrane organization GO:0007009 90 0.011
olfactory learning GO:0008355 2 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
b cell activation GO:0042113 161 0.011
regulation of neuron death GO:1901214 134 0.011
regulation of intracellular transport GO:0032386 159 0.011
sphingolipid metabolic process GO:0006665 45 0.011
nucleoside catabolic process GO:0009164 206 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
response to drug GO:0042493 75 0.011
response to light stimulus GO:0009416 135 0.011
membrane lipid metabolic process GO:0006643 53 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
phosphatidylinositol metabolic process GO:0046488 45 0.011
intracellular mrna localization GO:0008298 4 0.011
digestive tract morphogenesis GO:0048546 147 0.011
organ growth GO:0035265 117 0.011
cell maturation GO:0048469 127 0.011
cellular response to cadmium ion GO:0071276 3 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
cellular lipid catabolic process GO:0044242 52 0.011
lymphocyte proliferation GO:0046651 164 0.011
peptide secretion GO:0002790 114 0.011
skin development GO:0043588 220 0.011
nuclear import GO:0051170 95 0.011
response to growth factor GO:0070848 198 0.011
regulation of anatomical structure size GO:0090066 178 0.011
defense response to bacterium GO:0042742 119 0.011
response to insulin GO:0032868 100 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
transmission of nerve impulse GO:0019226 76 0.010
lymphocyte differentiation GO:0030098 242 0.010
adaptive immune response GO:0002250 155 0.010
cellularization GO:0007349 1 0.010
epidermis development GO:0008544 187 0.010
protein localization to nucleus GO:0034504 121 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
positive regulation of cytokine production GO:0001819 174 0.010
microglia development GO:0014005 2 0.010
response to oxygen radical GO:0000305 16 0.010
hormone metabolic process GO:0042445 86 0.010
negative regulation of protein maturation GO:1903318 79 0.010
response to steroid hormone GO:0048545 56 0.010
rhythmic process GO:0048511 174 0.010
regulation of cell projection organization GO:0031344 206 0.010
regulation of fat cell differentiation GO:0045598 81 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
learning or memory GO:0007611 148 0.010
digestive tract development GO:0048565 190 0.010
striated muscle myosin thick filament assembly GO:0071688 1 0.010
regulation of intracellular protein transport GO:0033157 82 0.010

Srxn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.033
disease of anatomical entity DOID:7 0 0.033
neuropathy DOID:870 0 0.032
musculoskeletal system disease DOID:17 0 0.030
neuromuscular disease DOID:440 0 0.024
organ system cancer DOID:0050686 0 0.019
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
connective tissue disease DOID:65 0 0.018
charcot marie tooth disease DOID:10595 0 0.017
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.015
bone disease DOID:0080001 0 0.013
immune system disease DOID:2914 0 0.012
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.010