Mus musculus

390 known processes

Stat5b

signal transducer and activator of transcription 5B

Stat5b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
creatinine metabolic process GO:0046449 3 1.000
response to granulocyte macrophage colony stimulating factor GO:0097012 3 1.000
Mouse
creatine metabolic process GO:0006600 4 0.999
citrate metabolic process GO:0006101 3 0.999
cellular response to granulocyte macrophage colony stimulating factor stimulus GO:0097011 3 0.999
Mouse
progesterone metabolic process GO:0042448 4 0.999
taurine metabolic process GO:0019530 4 0.998
cellular lactam metabolic process GO:0072338 3 0.998
negative regulation of glycolytic process GO:0045820 4 0.997
Mouse
succinate metabolic process GO:0006105 4 0.997
allantoin metabolic process GO:0000255 3 0.995
cellular response to growth hormone stimulus GO:0071378 7 0.990
development of secondary male sexual characteristics GO:0046544 3 0.989
response to interleukin 2 GO:0070669 2 0.989
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.985
jak stat cascade involved in growth hormone signaling pathway GO:0060397 4 0.984
interleukin 4 mediated signaling pathway GO:0035771 2 0.983
Mouse
positive regulation of activated t cell proliferation GO:0042104 8 0.982
interleukin 2 biosynthetic process GO:0042094 15 0.981
positive regulation of gamma delta t cell differentiation GO:0045588 6 0.981
negative regulation of macrophage fusion GO:0034240 1 0.980
Mouse
isoleucine metabolic process GO:0006549 4 0.980
negative regulation of erythrocyte differentiation GO:0045647 5 0.979
regulation of mast cell apoptotic process GO:0033025 5 0.978
Mouse
positive regulation of isotype switching to ige isotypes GO:0048295 4 0.977
Mouse
response to growth hormone GO:0060416 7 0.974
cellular response to x ray GO:0071481 2 0.974
Fly
mast cell proliferation GO:0070662 4 0.973
Mouse
cd4 positive alpha beta t cell lineage commitment GO:0043373 6 0.972
Mouse
negative regulation of syncytium formation by plasma membrane fusion GO:0034242 5 0.966
Mouse
cd4 positive alpha beta t cell activation GO:0035710 45 0.964
Mouse
macrophage fusion GO:0034238 3 0.964
Mouse
positive regulation of natural killer cell differentiation GO:0032825 7 0.963
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.959
t helper 1 cell lineage commitment GO:0002296 2 0.959
Mouse
phospholipid homeostasis GO:0055091 6 0.953
Mouse
positive regulation of natural killer cell proliferation GO:0032819 2 0.949
regulation of b cell differentiation GO:0045577 23 0.948
cellular response to interleukin 4 GO:0071353 21 0.947
Mouse
type i interferon signaling pathway GO:0060337 10 0.946
Mouse
carbohydrate catabolic process GO:0016052 32 0.937
Mouse
erythrocyte differentiation GO:0030218 88 0.937
positive regulation of interleukin 2 biosynthetic process GO:0045086 8 0.935
regulation of mast cell proliferation GO:0070666 4 0.932
Mouse
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.932
regulation of natural killer cell proliferation GO:0032817 2 0.931
regulation of macrophage fusion GO:0034239 3 0.924
Mouse
eye photoreceptor cell differentiation GO:0001754 41 0.916
Mouse
cellular carbohydrate catabolic process GO:0044275 15 0.915
Mouse
negative regulation of myeloid cell differentiation GO:0045638 38 0.914
regulation of antimicrobial humoral response GO:0002759 3 0.906
Fly
dicarboxylic acid metabolic process GO:0043648 18 0.903
lactation GO:0007595 25 0.900
glycolytic process GO:0006096 20 0.896
Mouse
positive regulation of endopeptidase activity GO:0010950 43 0.894
Mouse
generation of precursor metabolites and energy GO:0006091 103 0.893
Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.892
Mouse
regulation of natural killer cell mediated immunity GO:0002715 19 0.892
positive regulation of b cell differentiation GO:0045579 13 0.891
positive regulation of b cell mediated immunity GO:0002714 26 0.888
Mouse
negative regulation of cellular carbohydrate metabolic process GO:0010677 19 0.887
Mouse
somatic diversification of immune receptors GO:0002200 53 0.885
Mouse
sulfur compound metabolic process GO:0006790 100 0.877
tricarboxylic acid metabolic process GO:0072350 5 0.871
mucosal associated lymphoid tissue development GO:0048537 12 0.863
oxaloacetate metabolic process GO:0006107 5 0.862
alpha beta t cell differentiation GO:0046632 69 0.860
Mouse
regulation of type 2 immune response GO:0002828 18 0.859
Mouse
stem cell maintenance GO:0019827 130 0.858
Mouse Fly
somatic cell dna recombination GO:0016444 51 0.850
Mouse
t cell activation GO:0042110 289 0.849
regulation of t cell activation GO:0050863 170 0.848
2 oxoglutarate metabolic process GO:0006103 7 0.843
positive regulation of mast cell proliferation GO:0070668 3 0.843
Mouse
lymphocyte homeostasis GO:0002260 64 0.842
regulation of natural killer cell activation GO:0032814 22 0.841
positive regulation of natural killer cell activation GO:0032816 15 0.838
cellular response to interferon gamma GO:0071346 25 0.835
Mouse
leukocyte homeostasis GO:0001776 79 0.834
t cell proliferation GO:0042098 120 0.834
mast cell apoptotic process GO:0033024 5 0.834
Mouse
response to interleukin 4 GO:0070670 23 0.832
positive regulation of cell activation GO:0050867 158 0.831
regulation of interleukin 2 production GO:0032663 28 0.830
regulation of cell activation GO:0050865 289 0.825
cellular response to peptide GO:1901653 92 0.823
t cell differentiation GO:0030217 174 0.823
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.822
Mouse
growth hormone receptor signaling pathway GO:0060396 7 0.815
alpha beta t cell lineage commitment GO:0002363 7 0.814
Mouse
regulation of b cell mediated immunity GO:0002712 37 0.813
Mouse
segment specification GO:0007379 15 0.811
Fly
positive regulation of gamma delta t cell activation GO:0046645 6 0.810
positive regulation of mast cell differentiation GO:0060376 1 0.808
Mouse
regulation of interleukin 2 biosynthetic process GO:0045076 13 0.798
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.796
regulation of leukocyte mediated immunity GO:0002703 104 0.796
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.794
regulation of cytokine production GO:0001817 266 0.793
luteinization GO:0001553 8 0.790
positive regulation of notch signaling pathway GO:0045747 18 0.787
Mouse
digestive tract development GO:0048565 190 0.783
Fly
regulation of dna recombination GO:0000018 34 0.783
Mouse
positive regulation of t cell activation GO:0050870 101 0.782
regulation of cytokine biosynthetic process GO:0042035 59 0.781
regulation of t cell differentiation GO:0045580 83 0.780
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.778
Mouse
positive regulation of leukocyte proliferation GO:0070665 73 0.777
leukocyte activation involved in immune response GO:0002366 126 0.777
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.774
regionalization GO:0003002 337 0.773
Fly
regulation of natural killer cell differentiation GO:0032823 11 0.771
natural killer cell differentiation GO:0001779 21 0.768
t helper 1 cell differentiation GO:0045063 13 0.766
Mouse
pyruvate metabolic process GO:0006090 28 0.766
Mouse
alpha amino acid metabolic process GO:1901605 59 0.765
response to interferon gamma GO:0034341 34 0.759
Mouse
carbohydrate metabolic process GO:0005975 230 0.750
Mouse
natural killer cell activation GO:0030101 44 0.748
cytokine metabolic process GO:0042107 71 0.739
myeloid cell differentiation GO:0030099 233 0.739
natural killer cell mediated cytotoxicity GO:0042267 29 0.737
multicellular organism growth GO:0035264 161 0.737
regulation of insulin receptor signaling pathway GO:0046626 21 0.736
regulation of t cell proliferation GO:0042129 92 0.734
radial glial cell differentiation GO:0060019 6 0.731
Mouse
c21 steroid hormone metabolic process GO:0008207 7 0.729
lipid homeostasis GO:0055088 63 0.729
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.727
sensory organ morphogenesis GO:0090596 242 0.725
Mouse
regulation of carbohydrate metabolic process GO:0006109 75 0.722
Mouse
cytokine production GO:0001816 319 0.721
regulation of lymphocyte activation GO:0051249 240 0.716
regulation of gamma delta t cell differentiation GO:0045586 9 0.714
gamma delta t cell differentiation GO:0042492 11 0.712
positive regulation of lymphocyte activation GO:0051251 140 0.706
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.704
Mouse
regulation of glycolytic process GO:0006110 10 0.700
Mouse
somatic stem cell maintenance GO:0035019 47 0.697
Fly
regulation of gamma delta t cell activation GO:0046643 9 0.696
cellular ketone metabolic process GO:0042180 84 0.694
stem cell development GO:0048864 219 0.692
Mouse Fly
urogenital system development GO:0001655 261 0.686
Mouse
epithelial cell differentiation involved in prostate gland development GO:0060742 13 0.685
Mouse
regulation of activated t cell proliferation GO:0046006 16 0.680
digestive tract morphogenesis GO:0048546 147 0.678
Fly
natural killer cell mediated immunity GO:0002228 29 0.672
positive regulation of immunoglobulin production GO:0002639 28 0.669
Mouse
response to type i interferon GO:0034340 12 0.668
Mouse
response to x ray GO:0010165 11 0.667
Fly
female gonad development GO:0008585 71 0.667
mammary gland morphogenesis GO:0060443 54 0.667
Mouse
regulation of erythrocyte differentiation GO:0045646 23 0.664
somatic diversification of immunoglobulins GO:0016445 43 0.663
Mouse
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.659
Mouse
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.653
Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.649
cell killing GO:0001906 67 0.649
negative regulation of type 2 immune response GO:0002829 8 0.647
Mouse
female sex differentiation GO:0046660 84 0.646
positive regulation of leukocyte differentiation GO:1902107 86 0.645
activation of cysteine type endopeptidase activity GO:0097202 27 0.644
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.642
regulation of carbohydrate catabolic process GO:0043470 12 0.639
Mouse
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.639
Mouse
isotype switching GO:0045190 36 0.633
Mouse
positive t cell selection GO:0043368 23 0.631
Mouse
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 21 0.624
male sex differentiation GO:0046661 109 0.623
mast cell differentiation GO:0060374 5 0.621
Mouse
positive regulation of t cell differentiation GO:0045582 52 0.617
positive regulation of leukocyte mediated immunity GO:0002705 70 0.617
regulation of cellular ketone metabolic process GO:0010565 66 0.616
photoreceptor cell differentiation GO:0046530 52 0.613
Mouse
activation of janus kinase activity GO:0042976 2 0.610
ovulation cycle GO:0042698 59 0.610
negative regulation of cellular component organization GO:0051129 194 0.608
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.607
Mouse
b cell mediated immunity GO:0019724 71 0.599
Mouse
prostate gland epithelium morphogenesis GO:0060740 31 0.599
Mouse
leukocyte proliferation GO:0070661 172 0.590
regulation of myeloid leukocyte differentiation GO:0002761 58 0.589
Mouse
valine metabolic process GO:0006573 4 0.589
cellular response to cytokine stimulus GO:0071345 189 0.586
regulation of alpha beta t cell activation GO:0046634 53 0.585
type 2 immune response GO:0042092 23 0.579
Mouse
positive regulation of mitotic cell cycle GO:0045931 41 0.577
regulation of leukocyte proliferation GO:0070663 121 0.576
syncytium formation GO:0006949 43 0.575
Mouse
alpha beta t cell activation GO:0046631 91 0.572
Mouse
learning or memory GO:0007611 148 0.571
Fly
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.570
Mouse
t helper cell lineage commitment GO:0002295 6 0.569
Mouse
peyer s patch development GO:0048541 12 0.568
leukocyte mediated cytotoxicity GO:0001909 62 0.566
response to peptide hormone GO:0043434 127 0.566
development of secondary female sexual characteristics GO:0046543 8 0.565
development of primary female sexual characteristics GO:0046545 73 0.563
cytokine mediated signaling pathway GO:0019221 115 0.562
syncytium formation by plasma membrane fusion GO:0000768 42 0.559
Mouse
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.557
immunoglobulin production GO:0002377 73 0.557
Mouse
leukocyte mediated immunity GO:0002443 174 0.555
negative regulation of cell development GO:0010721 169 0.554
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.554
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.552
prolactin signaling pathway GO:0038161 5 0.547
myeloid leukocyte differentiation GO:0002573 119 0.544
Mouse
positive regulation of cell killing GO:0031343 33 0.542
negative regulation of mast cell apoptotic process GO:0033026 4 0.541
Mouse
response to molecule of bacterial origin GO:0002237 143 0.539
Mouse Rat Fly
glial cell differentiation GO:0010001 131 0.539
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 65 0.538
Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.530
regulation of immunoglobulin production GO:0002637 42 0.530
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.530
regulation of cellular carbohydrate catabolic process GO:0043471 12 0.524
Mouse
hormone metabolic process GO:0042445 86 0.516
lymphocyte mediated immunity GO:0002449 139 0.516
positive regulation of inflammatory response GO:0050729 47 0.516
regulation of body fluid levels GO:0050878 162 0.515
interleukin 2 production GO:0032623 33 0.513
positive regulation of cytokine production GO:0001819 174 0.511
cellular carbohydrate metabolic process GO:0044262 119 0.506
Mouse
positive regulation of lymphocyte proliferation GO:0050671 70 0.504
hormone mediated signaling pathway GO:0009755 23 0.503
cell activation involved in immune response GO:0002263 126 0.498
Mouse
positive regulation of apoptotic process GO:0043065 217 0.495
Mouse
positive regulation of t cell proliferation GO:0042102 52 0.494
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.493
Mouse
cellular response to hormone stimulus GO:0032870 150 0.493
regulation of cell adhesion GO:0030155 154 0.488
myeloid cell homeostasis GO:0002262 114 0.486
cytokine biosynthetic process GO:0042089 68 0.484
leukocyte apoptotic process GO:0071887 71 0.483
Mouse
embryonic placenta development GO:0001892 98 0.482
cellular response to lipid GO:0071396 145 0.482
Mouse Fly
lymphocyte differentiation GO:0030098 242 0.481
immune effector process GO:0002252 321 0.477
development of primary sexual characteristics GO:0045137 143 0.474
cellular amino acid metabolic process GO:0006520 103 0.473
cellular modified amino acid metabolic process GO:0006575 63 0.470
adaptive immune response GO:0002250 155 0.468
Mouse
cellular response to peptide hormone stimulus GO:0071375 92 0.463
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.457
Mouse
regulation of jak stat cascade GO:0046425 34 0.456
Fly
production of molecular mediator of immune response GO:0002440 103 0.455
Mouse
digestive system development GO:0055123 200 0.454
Fly
positive regulation of peptidase activity GO:0010952 49 0.454
Mouse
positive regulation of defense response GO:0031349 124 0.453
gland development GO:0048732 330 0.450
monosaccharide metabolic process GO:0005996 106 0.448
homeostasis of number of cells GO:0048872 210 0.444
positive regulation of cd4 positive alpha beta t cell differentiation GO:0043372 14 0.443
prostate gland morphogenesis GO:0060512 32 0.442
Mouse
fatty acid metabolic process GO:0006631 121 0.440
response to interleukin 15 GO:0070672 3 0.439
prostate gland development GO:0030850 48 0.438
Mouse
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.438
Mouse
branched chain amino acid metabolic process GO:0009081 6 0.430
positive regulation of immune effector process GO:0002699 107 0.429
regulation of adaptive immune response GO:0002819 90 0.428
Mouse
leukocyte differentiation GO:0002521 342 0.428
positive regulation of phagocytosis engulfment GO:0060100 3 0.425
regulation of kinase activity GO:0043549 249 0.421
regulation of leukocyte differentiation GO:1902105 159 0.418
cell adhesion GO:0007155 329 0.417
cell division GO:0051301 120 0.412
Fly
positive regulation of interleukin 2 production GO:0032743 19 0.411
regulation of immunoglobulin mediated immune response GO:0002889 37 0.409
Mouse
regulation of myeloid cell differentiation GO:0045637 96 0.406
t cell anergy GO:0002870 4 0.406
regulation of isotype switching GO:0045191 22 0.400
Mouse
t cell selection GO:0045058 34 0.399
Mouse
response to organonitrogen compound GO:0010243 246 0.398
t cell differentiation involved in immune response GO:0002292 30 0.395
Mouse
positive regulation of cell cycle GO:0045787 92 0.394
body fluid secretion GO:0007589 53 0.387
peptidyl tyrosine modification GO:0018212 145 0.387
Mouse
negative regulation of neuron death GO:1901215 98 0.386
response to radiation GO:0009314 165 0.383
Fly
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.382
Mouse
protein processing GO:0016485 163 0.381
Mouse
wnt signaling pathway GO:0016055 188 0.380
Fly
t cell lineage commitment GO:0002360 13 0.380
Mouse
regulation of peptidase activity GO:0052547 96 0.379
Mouse
regulation of cell motility GO:2000145 236 0.379
Mouse
blastoderm segmentation GO:0007350 13 0.371
Fly
immunoglobulin mediated immune response GO:0016064 69 0.371
Mouse
myeloid cell apoptotic process GO:0033028 22 0.370
Mouse
regulation of defense response to virus GO:0050688 18 0.366
Fly
negative regulation of cell motility GO:2000146 61 0.364
Mouse
mammary gland epithelial cell proliferation GO:0033598 24 0.348
Mouse
negative regulation of humoral immune response GO:0002921 6 0.347
Fly
regulation of wnt signaling pathway GO:0030111 123 0.346
Fly
positive regulation of isotype switching GO:0045830 15 0.343
Mouse
regulation of alpha beta t cell differentiation GO:0046637 35 0.343
b cell differentiation GO:0030183 78 0.339
regulation of b cell activation GO:0050864 81 0.337
positive regulation of adaptive immune response GO:0002821 61 0.335
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.334
gliogenesis GO:0042063 141 0.331
Mouse
dna metabolic process GO:0006259 303 0.330
Mouse
regulation of endopeptidase activity GO:0052548 89 0.329
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.326
Mouse Fly
temperature homeostasis GO:0001659 26 0.326
Mouse
negative regulation of cell proliferation GO:0008285 296 0.325
Mouse
regulation of interleukin 17 production GO:0032660 8 0.320
regulation of neuron death GO:1901214 134 0.316
protein polymerization GO:0051258 57 0.314
positive regulation of proteolysis GO:0045862 85 0.314
Mouse
protein maturation GO:0051604 176 0.309
Mouse
regulation of defense response to virus by host GO:0050691 8 0.309
Fly
peptidyl tyrosine phosphorylation GO:0018108 143 0.304
Mouse
positive regulation of glial cell proliferation GO:0060252 4 0.304
dna recombination GO:0006310 92 0.302
Mouse
positive regulation of lymphocyte differentiation GO:0045621 61 0.301
b cell activation GO:0042113 161 0.296
t cell homeostasis GO:0043029 35 0.295
cognition GO:0050890 149 0.293
Fly
regulation of lipid metabolic process GO:0019216 118 0.292
natural killer cell proliferation GO:0001787 3 0.290
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.285
Mouse
positive regulation of growth GO:0045927 104 0.280
neuron migration GO:0001764 122 0.278
Mouse
glucose homeostasis GO:0042593 128 0.274
Mouse
alpha beta t cell activation involved in immune response GO:0002287 31 0.272
Mouse
epithelial cell proliferation GO:0050673 174 0.271
Mouse
innate immune response GO:0045087 157 0.271
mammary gland lobule development GO:0061377 22 0.271
muscle cell differentiation GO:0042692 261 0.269
response to ethanol GO:0045471 18 0.269
Rat
cellular response to organonitrogen compound GO:0071417 145 0.269
mast cell homeostasis GO:0033023 5 0.267
Mouse
regulation of homeostatic process GO:0032844 182 0.265
negative regulation of cell migration GO:0030336 59 0.261
Mouse
segmentation GO:0035282 93 0.257
Fly
regulation of cell migration GO:0030334 219 0.255
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.253
cellular response to radiation GO:0071478 28 0.250
Fly
peptidyl amino acid modification GO:0018193 336 0.246
Mouse
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.243
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.240
regulation of cellular amino acid metabolic process GO:0006521 5 0.240
lipid localization GO:0010876 126 0.240
regulation of hydrolase activity GO:0051336 246 0.237
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.231
regulation of leukocyte apoptotic process GO:2000106 56 0.231
Mouse
development of secondary sexual characteristics GO:0045136 11 0.230
mammary gland involution GO:0060056 9 0.229
negative regulation of immune effector process GO:0002698 55 0.219
gonad development GO:0008406 141 0.218
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.217
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.212
negative regulation of phosphorus metabolic process GO:0010563 184 0.212
zymogen activation GO:0031638 41 0.212
Mouse
eating behavior GO:0042755 15 0.211
Mouse
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.211
post embryonic organ development GO:0048569 17 0.211
Fly
regulation of production of molecular mediator of immune response GO:0002700 65 0.209
Mouse
negative regulation of neuron migration GO:2001223 6 0.209
Mouse
cellular lipid metabolic process GO:0044255 323 0.208
positive regulation of response to wounding GO:1903036 66 0.207
jak stat cascade GO:0007259 42 0.204
cellular amine metabolic process GO:0044106 44 0.200
lymphocyte proliferation GO:0046651 164 0.198
response to organic cyclic compound GO:0014070 198 0.198
Human Mouse
positive regulation of innate immune response GO:0045089 80 0.193
positive regulation of cell death GO:0010942 224 0.192
Mouse
t helper cell differentiation GO:0042093 28 0.190
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.189
cellular response to abiotic stimulus GO:0071214 56 0.187
Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.187
response to lipopolysaccharide GO:0032496 128 0.185
Mouse Rat Fly
regulation of defense response GO:0031347 233 0.185
regulation of myeloid cell apoptotic process GO:0033032 19 0.179
Mouse
isotype switching to ige isotypes GO:0048289 7 0.179
Mouse
response to alcohol GO:0097305 48 0.177
Human Rat
regulation of lymphocyte anergy GO:0002911 4 0.177
response to dsrna GO:0043331 30 0.174
Mouse
regulation of gluconeogenesis GO:0006111 30 0.171
positive regulation of kinase activity GO:0033674 155 0.168
positive regulation of defense response to virus by host GO:0002230 6 0.165
Fly
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.163
defense response to other organism GO:0098542 197 0.161
Fly
regulation of protein kinase activity GO:0045859 232 0.157
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.156
Mouse
cell fate commitment GO:0045165 210 0.156
Mouse
response to peptide GO:1901652 136 0.156
regulation of glucose metabolic process GO:0010906 60 0.154
negative regulation of carbohydrate metabolic process GO:0045912 19 0.152
Mouse
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.151
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.148
mammary gland epithelium development GO:0061180 65 0.145
Mouse
regulation of actin filament polymerization GO:0030833 38 0.144
response to extracellular stimulus GO:0009991 127 0.144
carbohydrate biosynthetic process GO:0016051 74 0.144
lipid storage GO:0019915 36 0.144
male gamete generation GO:0048232 285 0.142
stem cell differentiation GO:0048863 268 0.141
Mouse Fly
hindgut morphogenesis GO:0007442 7 0.139
Fly
embryonic epithelial tube formation GO:0001838 130 0.139
positive regulation of alpha beta t cell activation GO:0046635 39 0.138
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.138
embryonic organ morphogenesis GO:0048562 276 0.135
stem cell division GO:0017145 30 0.134
Fly
inflammatory response GO:0006954 244 0.134
cellular response to ionizing radiation GO:0071479 11 0.131
Fly
neural tube closure GO:0001843 90 0.130
epithelial tube formation GO:0072175 130 0.127
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.127
Mouse
regulation of mapk cascade GO:0043408 248 0.124
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.123
cytoplasmic transport GO:0016482 234 0.122
regulation of transferase activity GO:0051338 263 0.122
t cell activation involved in immune response GO:0002286 43 0.121
Mouse
hindbrain development GO:0030902 128 0.121
regulation of notch signaling pathway GO:0008593 35 0.120
Mouse
positive regulation of myeloid cell differentiation GO:0045639 43 0.118
Zebrafish Mouse
regulation of isotype switching to ige isotypes GO:0048293 7 0.118
Mouse
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.117
Mouse
negative regulation of molecular function GO:0044092 258 0.117
regulation of humoral immune response GO:0002920 22 0.117
Fly
t helper 1 type immune response GO:0042088 25 0.116
Mouse
defense response to virus GO:0051607 68 0.116
Fly
regulation of hormone levels GO:0010817 211 0.114
wound healing GO:0042060 157 0.112
feeding behavior GO:0007631 62 0.110
Mouse
positive regulation of mapk cascade GO:0043410 170 0.110
mesenchyme development GO:0060485 152 0.110
regulation of cell cycle GO:0051726 281 0.109
negative regulation of interleukin 6 production GO:0032715 17 0.108
mapk cascade GO:0000165 281 0.108
morphogenesis of embryonic epithelium GO:0016331 159 0.107
neural tube formation GO:0001841 108 0.107
positive regulation of organelle organization GO:0010638 128 0.106
humoral immune response GO:0006959 57 0.105
Fly
cell migration involved in gastrulation GO:0042074 13 0.103
cellular ion homeostasis GO:0006873 165 0.101
regulation of striated muscle cell differentiation GO:0051153 81 0.101
regulation of organelle organization GO:0033043 289 0.101
lymphocyte activation involved in immune response GO:0002285 93 0.100
Mouse
b cell activation involved in immune response GO:0002312 50 0.100
Mouse
positive regulation of transferase activity GO:0051347 167 0.100
negative regulation of nervous system development GO:0051961 156 0.098
Mouse
neuron death GO:0070997 154 0.097
regulation of hormone secretion GO:0046883 88 0.096
negative regulation of cytokine production GO:0001818 84 0.095
negative regulation of immune system process GO:0002683 209 0.095
interleukin 6 production GO:0032635 58 0.093
striated muscle cell development GO:0055002 125 0.093
tube closure GO:0060606 91 0.093
regulation of steroid metabolic process GO:0019218 39 0.092
nuclear transport GO:0051169 139 0.092
positive regulation of b cell activation GO:0050871 49 0.091
primary neural tube formation GO:0014020 95 0.089
muscle system process GO:0003012 141 0.089
regulation of carbohydrate biosynthetic process GO:0043255 40 0.089
carbohydrate homeostasis GO:0033500 128 0.088
Mouse
cell type specific apoptotic process GO:0097285 268 0.086
Mouse
maintenance of location GO:0051235 89 0.086
negative regulation of protein phosphorylation GO:0001933 126 0.085
epithelial cell development GO:0002064 159 0.085
Fly
mammary gland alveolus development GO:0060749 22 0.083
tyrosine phosphorylation of stat protein GO:0007260 23 0.083
negative regulation of cellular amine metabolic process GO:0033239 1 0.082
rhythmic process GO:0048511 174 0.082
regulation of t cell anergy GO:0002667 4 0.082
positive regulation of behavior GO:0048520 40 0.081
negative regulation of defense response GO:0031348 77 0.081
regulation of t helper 1 cell differentiation GO:0045625 7 0.080
embryonic heart tube development GO:0035050 65 0.079
regulation of interleukin 6 production GO:0032675 55 0.078
apoptotic signaling pathway GO:0097190 306 0.078
regulation of secretion by cell GO:1903530 249 0.078
asymmetric stem cell division GO:0098722 3 0.077
b cell homeostasis GO:0001782 34 0.077
germ line stem cell maintenance GO:0030718 6 0.077
Fly
negative regulation of cellular protein metabolic process GO:0032269 247 0.077
negative regulation of neuron apoptotic process GO:0043524 92 0.076
metencephalon development GO:0022037 89 0.076
response to inactivity GO:0014854 4 0.076
muscle cell proliferation GO:0033002 52 0.075
Rat
ribonucleoside metabolic process GO:0009119 245 0.075
cation homeostasis GO:0055080 212 0.074
regulation of protein serine threonine kinase activity GO:0071900 157 0.074
regulation of establishment of protein localization GO:0070201 181 0.072
neuron projection guidance GO:0097485 141 0.072
divalent metal ion transport GO:0070838 172 0.072
mesodermal cell migration GO:0008078 4 0.071
positive regulation of apoptotic signaling pathway GO:2001235 95 0.071
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.070
tyrosine phosphorylation of stat3 protein GO:0042503 12 0.070
nuclear import GO:0051170 95 0.069
actin cytoskeleton organization GO:0030036 220 0.069
covalent chromatin modification GO:0016569 163 0.069

Stat5b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.161
immune system disease DOID:2914 0 0.094
disease of anatomical entity DOID:7 0 0.094