|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.975
|
|
|
|
positive regulation of macrophage activation
|
GO:0043032 |
10 |
0.975
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.970
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.965
|
Mouse |
|
|
regulation of chemokine secretion
|
GO:0090196 |
4 |
0.959
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.953
|
Mouse Fly |
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.951
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.943
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.942
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.940
|
Mouse |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.939
|
Fly |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.937
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.935
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.931
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.925
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.923
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.892
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.874
|
Mouse |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.871
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.853
|
Mouse |
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.851
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.843
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.836
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.834
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.832
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.828
|
Mouse |
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.791
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.790
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.790
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.790
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.788
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.786
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.780
|
Mouse |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.780
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.776
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.771
|
|
|
|
regulation of macrophage activation
|
GO:0043030 |
17 |
0.752
|
|
|
|
t helper 1 cell lineage commitment
|
GO:0002296 |
2 |
0.742
|
|
|
|
positive regulation of chemokine secretion
|
GO:0090197 |
4 |
0.736
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.727
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.714
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.713
|
|
|
|
isotype switching to ige isotypes
|
GO:0048289 |
7 |
0.703
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.696
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.692
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.686
|
Mouse |
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.680
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.668
|
Mouse |
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.665
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.661
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.645
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.642
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.640
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.640
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.638
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.619
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.610
|
Mouse |
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.609
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.609
|
Mouse |
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.608
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.597
|
Mouse |
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.590
|
Mouse |
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.588
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.583
|
Mouse |
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.581
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.579
|
Mouse |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.579
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.574
|
Mouse Fly |
|
|
syncytium formation
|
GO:0006949 |
43 |
0.568
|
Mouse |
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.562
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.553
|
Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.545
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.540
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.540
|
Mouse |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.538
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.532
|
Mouse |
|
|
negative regulation of t helper 1 type immune response
|
GO:0002826 |
5 |
0.531
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.529
|
Mouse |
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.522
|
Mouse |
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.508
|
|
|
|
positive regulation of isotype switching to ige isotypes
|
GO:0048295 |
4 |
0.503
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.502
|
Mouse Fly |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.498
|
|
|
|
macrophage activation
|
GO:0042116 |
27 |
0.490
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.483
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.478
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.476
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.470
|
Mouse |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.459
|
Mouse Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.444
|
Mouse |
|
|
negative regulation of t helper 1 cell differentiation
|
GO:0045626 |
3 |
0.442
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.441
|
Mouse |
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.435
|
Mouse |
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.434
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.431
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.424
|
Mouse |
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.421
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.419
|
Mouse |
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.409
|
|
|
|
positive regulation of type 2 immune response
|
GO:0002830 |
9 |
0.409
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.406
|
Mouse |
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.405
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.400
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.398
|
Mouse |
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.398
|
Mouse |
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.390
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.389
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.385
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.381
|
Mouse |
|
|
positive regulation of isotype switching
|
GO:0045830 |
15 |
0.378
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.368
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.366
|
|
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
4 |
0.361
|
Mouse |
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.358
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.358
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.354
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.352
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.351
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.346
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.342
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.340
|
Mouse |
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.339
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.337
|
Mouse |
|
|
response to drug
|
GO:0042493 |
75 |
0.337
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.333
|
Fly |
|
|
citrate metabolic process
|
GO:0006101 |
3 |
0.327
|
Mouse |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.327
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.327
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.326
|
Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.319
|
Mouse |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.319
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.316
|
Mouse |
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.314
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.312
|
Mouse |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.312
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.311
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.310
|
|
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.309
|
Mouse |
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.309
|
Mouse |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.308
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.307
|
Rat |
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.306
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.303
|
Mouse |
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.303
|
|
|
|
negative regulation of interferon gamma production
|
GO:0032689 |
18 |
0.302
|
|
|
|
chemokine secretion
|
GO:0090195 |
5 |
0.301
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.299
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.297
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.296
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.296
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.291
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.290
|
Mouse Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.288
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.287
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.287
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.285
|
Mouse |
|
|
t cell activation
|
GO:0042110 |
289 |
0.281
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.280
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.278
|
Fly |
|
|
dna recombination
|
GO:0006310 |
92 |
0.276
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.275
|
Mouse |
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.275
|
Mouse |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.275
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
23 |
0.273
|
Mouse |
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.272
|
Mouse |
|
|
regulation of mast cell differentiation
|
GO:0060375 |
3 |
0.271
|
Mouse |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.268
|
Mouse |
|
|
cation transport
|
GO:0006812 |
399 |
0.268
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.268
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.266
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.265
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.261
|
Mouse |
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.258
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.256
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.255
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.255
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.255
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.251
|
Mouse |
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.248
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.248
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.247
|
|
|
|
cellular response to interleukin 4
|
GO:0071353 |
21 |
0.247
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.246
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.246
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.245
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.244
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.243
|
Mouse |
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.243
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.239
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.238
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.236
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.235
|
Mouse |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.233
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.232
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.232
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.229
|
Mouse Fly |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.229
|
Mouse |
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.228
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.227
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.224
|
Mouse |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.223
|
|
|
|
response to interleukin 15
|
GO:0070672 |
3 |
0.219
|
Mouse |
|
|
microtubule based process
|
GO:0007017 |
236 |
0.218
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.216
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.216
|
Mouse |
|
|
protein maturation
|
GO:0051604 |
176 |
0.215
|
Mouse |
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.214
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.214
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.212
|
Mouse |
|
|
positive regulation of mast cell degranulation
|
GO:0043306 |
10 |
0.212
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.211
|
Mouse |
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.211
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.210
|
|
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.209
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.209
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.208
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.207
|
|
|
|
negative regulation of cd4 positive alpha beta t cell activation
|
GO:2000515 |
10 |
0.206
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.206
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.205
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.205
|
|
|
|
ovulation
|
GO:0030728 |
15 |
0.205
|
|
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
11 |
0.203
|
Mouse |
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.201
|
Mouse |
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.199
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.199
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.198
|
Mouse |
|
|
b cell activation
|
GO:0042113 |
161 |
0.197
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.195
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.194
|
Mouse |
|
|
regulation of isotype switching to ige isotypes
|
GO:0048293 |
7 |
0.193
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.192
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.191
|
|
|
|
positive regulation of activated t cell proliferation
|
GO:0042104 |
8 |
0.187
|
Mouse |
|
|
natural killer cell proliferation
|
GO:0001787 |
3 |
0.184
|
Mouse |
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.183
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.182
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.181
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.181
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.180
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.180
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.178
|
Mouse |
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.178
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.177
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.177
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.174
|
|
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.174
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.173
|
Mouse |
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.171
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.169
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.169
|
Mouse |
|
|
germ cell development
|
GO:0007281 |
185 |
0.169
|
Fly |
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.168
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.168
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.167
|
Mouse |
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.167
|
|
|
|
positive regulation of t helper 2 cell differentiation
|
GO:0045630 |
4 |
0.167
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.163
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.163
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.163
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.162
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.162
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.162
|
Mouse |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.160
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.159
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.159
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.159
|
Mouse |
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.158
|
|
|
|
negative regulation of alpha beta t cell differentiation
|
GO:0046639 |
12 |
0.158
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.158
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.157
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.157
|
Mouse |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.156
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.155
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.155
|
Mouse Fly |
|
|
positive regulation of natural killer cell activation
|
GO:0032816 |
15 |
0.154
|
Mouse |
|
|
lysosome localization
|
GO:0032418 |
20 |
0.154
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.151
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.151
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.150
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.150
|
Mouse |
|
|
natural killer cell differentiation
|
GO:0001779 |
21 |
0.149
|
Mouse |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.147
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.147
|
Fly |
|
|
response to alcohol
|
GO:0097305 |
48 |
0.147
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.146
|
Fly |
|
|
regulation of myd88 independent toll like receptor signaling pathway
|
GO:0034127 |
1 |
0.145
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.145
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.143
|
Mouse |
|
|
chromatin organization
|
GO:0006325 |
206 |
0.143
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.142
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.142
|
Mouse |
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.142
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.142
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.141
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.138
|
|
|
|
interleukin 2 biosynthetic process
|
GO:0042094 |
15 |
0.138
|
Mouse |
|
|
chemokine production
|
GO:0032602 |
34 |
0.138
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.136
|
Mouse |
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.136
|
Mouse |
|
|
creatine metabolic process
|
GO:0006600 |
4 |
0.134
|
Mouse |
|
|
histone modification
|
GO:0016570 |
159 |
0.133
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.133
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.131
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.131
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.131
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.130
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.130
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.130
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.129
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.128
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.128
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.128
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.127
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.127
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.127
|
|
|
|
myd88 dependent toll like receptor signaling pathway
|
GO:0002755 |
7 |
0.126
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.126
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
34 |
0.125
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.124
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.123
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.123
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.123
|
|
|
|
mammary gland epithelial cell proliferation
|
GO:0033598 |
24 |
0.123
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.122
|
Fly |
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.121
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.120
|
|
|
|
regulation of interleukin 13 secretion
|
GO:2000665 |
2 |
0.119
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.118
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.118
|
|
|
|
response to interleukin 4
|
GO:0070670 |
23 |
0.117
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.117
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.116
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.116
|
Mouse |
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.115
|
Mouse |
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.113
|
Fly |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.113
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.112
|
Mouse |
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.112
|
Mouse |
|
|
amide transport
|
GO:0042886 |
138 |
0.112
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.112
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.111
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.111
|
|
|
|
t cell homeostasis
|
GO:0043029 |
35 |
0.111
|
Mouse |
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.110
|
Mouse |
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
27 |
0.108
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.108
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.108
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.108
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.107
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.107
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.107
|
|
|
|
taurine metabolic process
|
GO:0019530 |
4 |
0.107
|
Mouse |
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.107
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.107
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.106
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.106
|
Mouse |
|
|
mast cell activation
|
GO:0045576 |
27 |
0.106
|
|
|
|
chemokine biosynthetic process
|
GO:0042033 |
8 |
0.105
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.105
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.105
|
Mouse |
|
|
positive regulation of actin nucleation
|
GO:0051127 |
3 |
0.104
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.104
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.103
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.103
|
Mouse |
|
|
lipid localization
|
GO:0010876 |
126 |
0.103
|
Mouse |
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.103
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.103
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.101
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.101
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.101
|
Mouse |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.100
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.100
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.099
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.098
|
|
|
|
positive regulation of mast cell differentiation
|
GO:0060376 |
1 |
0.097
|
Mouse |
|
|
positive regulation of dna recombination
|
GO:0045911 |
17 |
0.097
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.096
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.096
|
|
|
|
interferon beta production
|
GO:0032608 |
16 |
0.095
|
|
|
|
regulation of actin nucleation
|
GO:0051125 |
4 |
0.095
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.095
|
Mouse |
|
|
wound healing
|
GO:0042060 |
157 |
0.094
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.094
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.093
|
|
|
|
positive regulation of lymphocyte anergy
|
GO:0002913 |
4 |
0.093
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.093
|
Mouse |
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.092
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.091
|
Mouse |
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.091
|
|
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
7 |
0.091
|
Mouse |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.090
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
4 |
0.090
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.090
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
20 |
0.089
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.089
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.089
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.089
|
Mouse |
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.089
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.088
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.088
|
|
|
|
response to protozoan
|
GO:0001562 |
28 |
0.088
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.087
|
|
|
|
interleukin 18 mediated signaling pathway
|
GO:0035655 |
2 |
0.086
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.086
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.086
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.085
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.085
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.085
|
|
|
|
regulation of t cell anergy
|
GO:0002667 |
4 |
0.085
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.085
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.084
|
Mouse |
|
|
protein secretion
|
GO:0009306 |
111 |
0.084
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
18 |
0.084
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.084
|
|
|
|
atp metabolic process
|
GO:0046034 |
75 |
0.083
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.083
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.082
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.082
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.081
|
|
|
|
luteinization
|
GO:0001553 |
8 |
0.081
|
Mouse |
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.081
|
Mouse |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.081
|
Mouse |
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.081
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.080
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.080
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.080
|
|
|
|
negative regulation of macrophage fusion
|
GO:0034240 |
1 |
0.080
|
Mouse |
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.080
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.080
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.079
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.079
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.079
|
Mouse |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.079
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.079
|
Mouse |
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.079
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.079
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.079
|
Mouse |
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.078
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.078
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.078
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.077
|
|
|
|
positive regulation of striated muscle cell differentiation
|
GO:0051155 |
35 |
0.077
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.077
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.077
|
Mouse |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.077
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.077
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.076
|
Mouse |
|
|
organ regeneration
|
GO:0031100 |
2 |
0.076
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.076
|
|
|
|
negative regulation of lymphocyte mediated immunity
|
GO:0002707 |
21 |
0.075
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.075
|
|
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.075
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.074
|
Mouse |
|
|
t helper 17 cell lineage commitment
|
GO:0072540 |
4 |
0.074
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.074
|
Mouse |
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.074
|
|
|
|
myosin filament organization
|
GO:0031033 |
3 |
0.074
|
|
|
|
positive regulation of myotube differentiation
|
GO:0010831 |
24 |
0.074
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.073
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.073
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
23 |
0.072
|
Mouse |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.072
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.072
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.072
|
Mouse |
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.072
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.071
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.071
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.071
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.070
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.070
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.069
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.069
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.069
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.069
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.069
|
Mouse |
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.069
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.069
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.068
|
|
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.067
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.067
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.067
|
|
|
|
regulation of natural killer cell proliferation
|
GO:0032817 |
2 |
0.067
|
Mouse |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.067
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.066
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.066
|
|
