Mus musculus

249 known processes

Sumo1

SMT3 suppressor of mif two 3 homolog 1 (yeast)

(Aliases: SUMO-1,Smt3C,PIC1,SMT3H3,SMT3,MGC103203,SMTP3,Ubl1,GMP1,SENTRIN)

Sumo1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation or removal GO:0070647 207 0.496
hypoxia inducible factor 1alpha signaling pathway GO:0097411 2 0.472
cellular macromolecule catabolic process GO:0044265 206 0.369
Human
spermatid differentiation GO:0048515 115 0.228
spermatid development GO:0007286 108 0.218
positive regulation of protein modification process GO:0031401 299 0.186
regulation of kinase activity GO:0043549 249 0.183
epithelial cell proliferation GO:0050673 174 0.176
modification dependent macromolecule catabolic process GO:0043632 133 0.156
Human
ubiquitin dependent protein catabolic process GO:0006511 129 0.152
Human
modification dependent protein catabolic process GO:0019941 133 0.151
Human
positive regulation of cell death GO:0010942 224 0.143
regulation of cell cycle GO:0051726 281 0.142
rna splicing GO:0008380 54 0.136
spermatogenesis GO:0007283 284 0.135
regulation of protein kinase activity GO:0045859 232 0.133
regulation of cellular component biogenesis GO:0044087 181 0.132
Human
protein sumoylation GO:0016925 14 0.125
mitotic cell cycle GO:0000278 195 0.117
germ cell development GO:0007281 185 0.103
male gamete generation GO:0048232 285 0.103
amine metabolic process GO:0009308 45 0.103
protein catabolic process GO:0030163 221 0.103
Human
regulation of cellular amine metabolic process GO:0033238 20 0.103
nucleoside phosphate metabolic process GO:0006753 338 0.101
protein modification by small protein conjugation GO:0032446 187 0.094
dendrite development GO:0016358 115 0.084
regulation of cellular component size GO:0032535 121 0.084
stem cell development GO:0048864 219 0.083
protein neddylation GO:0045116 1 0.077
microtubule cytoskeleton organization GO:0000226 157 0.073
positive regulation of cellular protein catabolic process GO:1903364 34 0.073
Human
organelle fission GO:0048285 170 0.071
regulation of transferase activity GO:0051338 263 0.070
response to decreased oxygen levels GO:0036293 59 0.069
positive regulation of receptor biosynthetic process GO:0010870 1 0.068
response to oxygen levels GO:0070482 62 0.066
purine ribonucleotide metabolic process GO:0009150 290 0.066
protein ubiquitination GO:0016567 171 0.065
regulation of receptor biosynthetic process GO:0010869 2 0.063
proteasomal protein catabolic process GO:0010498 98 0.062
Human
nitrogen compound transport GO:0071705 271 0.061
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.061
nucleoside phosphate catabolic process GO:1901292 222 0.060
oxygen homeostasis GO:0032364 2 0.060
cellular response to dna damage stimulus GO:0006974 207 0.060
rna processing GO:0006396 105 0.059
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.059
Human
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.058
Human
regulation of epithelial cell proliferation GO:0050678 141 0.056
positive regulation of protein phosphorylation GO:0001934 242 0.056
negative regulation of cell proliferation GO:0008285 296 0.055
meiotic cell cycle GO:0051321 122 0.055
learning or memory GO:0007611 148 0.054
cellular protein catabolic process GO:0044257 155 0.053
Human
regionalization GO:0003002 337 0.053
regulation of cellular response to hypoxia GO:1900037 2 0.052
cell division GO:0051301 120 0.051
regulation of neuron apoptotic process GO:0043523 122 0.051
purine nucleotide metabolic process GO:0006163 302 0.050
regulation of ion transport GO:0043269 215 0.049
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.049
cellular nitrogen compound catabolic process GO:0044270 280 0.048
dna metabolic process GO:0006259 303 0.044
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.044
dna replication GO:0006260 52 0.043
regulation of mitotic cell cycle GO:0007346 126 0.042
meiotic chromosome segregation GO:0045132 19 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.040
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.040
Human
regulation of cellular response to stress GO:0080135 159 0.040
single fertilization GO:0007338 82 0.040
regulation of cell cycle process GO:0010564 160 0.040
regulation of protein catabolic process GO:0042176 108 0.040
Human
regulation of peptidase activity GO:0052547 96 0.039
microtubule based process GO:0007017 236 0.039
oogenesis GO:0048477 56 0.038
canonical wnt signaling pathway GO:0060070 130 0.038
positive regulation of cellular amine metabolic process GO:0033240 5 0.038
peptidyl amino acid modification GO:0018193 336 0.037
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.037
organelle localization GO:0051640 179 0.036
organic cyclic compound catabolic process GO:1901361 295 0.036
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.036
regulation of protein stability GO:0031647 52 0.036
keratinocyte development GO:0003334 10 0.036
hormone secretion GO:0046879 128 0.036
posttranscriptional regulation of gene expression GO:0010608 155 0.035
columnar cuboidal epithelial cell maturation GO:0002069 4 0.034
purine nucleotide catabolic process GO:0006195 211 0.033
epithelial tube formation GO:0072175 130 0.033
regulation of cellular catabolic process GO:0031329 242 0.033
cation transport GO:0006812 399 0.032
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.032
receptor biosynthetic process GO:0032800 3 0.032
response to steroid hormone GO:0048545 56 0.032
connective tissue replacement involved in inflammatory response wound healing GO:0002248 3 0.031
positive regulation of hydrolase activity GO:0051345 148 0.031
cell fate commitment GO:0045165 210 0.031
heterocycle catabolic process GO:0046700 280 0.030
cellularization GO:0007349 1 0.030
pallium development GO:0021543 120 0.030
macromolecule catabolic process GO:0009057 281 0.030
Human
sperm individualization GO:0007291 1 0.030
positive regulation of proteolysis GO:0045862 85 0.030
Human
regulation of hormone levels GO:0010817 211 0.030
cognition GO:0050890 149 0.029
positive regulation of protein kinase activity GO:0045860 144 0.028
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.028
regulation of binding GO:0051098 111 0.028
Human
meiotic nuclear division GO:0007126 115 0.028
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.028
recombinational repair GO:0000725 21 0.028
g1 s transition of mitotic cell cycle GO:0000082 57 0.028
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.028
embryonic organ morphogenesis GO:0048562 276 0.028
signal transduction by p53 class mediator GO:0072331 51 0.028
intestinal epithelial cell maturation GO:0060574 2 0.028
response to hypoxia GO:0001666 58 0.027
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.027
positive regulation of cellular component biogenesis GO:0044089 94 0.027
Human
regulation of mitotic cell cycle phase transition GO:1901990 73 0.026
response to organic cyclic compound GO:0014070 198 0.026
establishment of organelle localization GO:0051656 122 0.026
positive regulation of kinase activity GO:0033674 155 0.026
cell type specific apoptotic process GO:0097285 268 0.026
dna integrity checkpoint GO:0031570 28 0.026
ribonucleotide metabolic process GO:0009259 291 0.025
epithelial cell differentiation involved in mammary gland alveolus development GO:0061030 4 0.025
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.025
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.024
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.024
regulation of mapk cascade GO:0043408 248 0.024
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.024
protein maturation GO:0051604 176 0.024
regulation of cysteine type endopeptidase activity GO:2000116 65 0.024
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.024
organophosphate catabolic process GO:0046434 232 0.024
rna interference GO:0016246 2 0.024
response to peptide GO:1901652 136 0.024
purine containing compound metabolic process GO:0072521 311 0.024
molting cycle GO:0042303 90 0.023
digestive tract morphogenesis GO:0048546 147 0.023
glucose homeostasis GO:0042593 128 0.023
regulation of proteolysis GO:0030162 164 0.023
Human
regulation of cell growth GO:0001558 91 0.022
oocyte construction GO:0007308 2 0.022
neural fold elevation formation GO:0021502 1 0.022
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
heart process GO:0003015 94 0.022
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.022
Human
morphogenesis of embryonic epithelium GO:0016331 159 0.022
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.022
intracellular protein transport GO:0006886 204 0.021
respiratory tube development GO:0030323 167 0.021
fertilization GO:0009566 127 0.021
primary neural tube formation GO:0014020 95 0.021
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.021
Human
cell cycle checkpoint GO:0000075 47 0.021
regulation of cytoskeleton organization GO:0051493 122 0.021
meiotic cell cycle process GO:1903046 77 0.021
camera type eye development GO:0043010 266 0.021
negative regulation of cell cycle process GO:0010948 69 0.021
respiratory system development GO:0060541 190 0.021
regulation of cellular response to growth factor stimulus GO:0090287 82 0.020
cytokinesis GO:0000910 17 0.020
positive regulation of endopeptidase activity GO:0010950 43 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
blood vessel morphogenesis GO:0048514 285 0.020
neural tube formation GO:0001841 108 0.020
cellular carbohydrate metabolic process GO:0044262 119 0.019
negative regulation of epithelial cell proliferation GO:0050680 64 0.019
cell growth GO:0016049 130 0.019
multicellular organismal response to stress GO:0033555 62 0.019
regulation of cell cycle phase transition GO:1901987 77 0.019
nucleocytoplasmic transport GO:0006913 139 0.019
ras protein signal transduction GO:0007265 77 0.019
mrna splicing via spliceosome GO:0000398 43 0.019
chromatin organization GO:0006325 206 0.019
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 2 0.019
carboxylic acid biosynthetic process GO:0046394 86 0.018
regulation of organelle organization GO:0033043 289 0.018
regulation of cell size GO:0008361 72 0.018
nucleotide metabolic process GO:0009117 332 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
blood circulation GO:0008015 195 0.018
cellular lipid metabolic process GO:0044255 323 0.018
regulation of system process GO:0044057 200 0.018
epidermis development GO:0008544 187 0.018
mapk cascade GO:0000165 281 0.018
regulation of lymphocyte differentiation GO:0045619 107 0.018
neural crest cell differentiation GO:0014033 54 0.017
fibroblast proliferation GO:0048144 35 0.017
cellular response to inorganic substance GO:0071241 37 0.017
protein localization to organelle GO:0033365 185 0.017
neuromuscular process GO:0050905 99 0.017
angiogenesis GO:0001525 201 0.017
positive regulation of cell cycle GO:0045787 92 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
regulation of actin cytoskeleton organization GO:0032956 84 0.017
regulation of anatomical structure size GO:0090066 178 0.017
negative regulation of tor signaling GO:0032007 13 0.017
positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774 13 0.017
transmembrane transport GO:0055085 412 0.017
cellular response to hormone stimulus GO:0032870 150 0.016
organic acid biosynthetic process GO:0016053 86 0.016
negative regulation of b cell activation GO:0050869 27 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
telencephalon development GO:0021537 186 0.016
synapse organization GO:0050808 125 0.016
carbohydrate metabolic process GO:0005975 230 0.016
actin cytoskeleton organization GO:0030036 220 0.016
regulation of cell cycle g1 s phase transition GO:1902806 35 0.016
regulation of heart contraction GO:0008016 77 0.016
tube formation GO:0035148 140 0.016
myeloid cell homeostasis GO:0002262 114 0.016
amide transport GO:0042886 138 0.016
positive regulation of dna templated transcription elongation GO:0032786 2 0.016
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.016
positive regulation of protein catabolic process GO:0045732 60 0.016
Human
positive regulation of cellular catabolic process GO:0031331 148 0.016
cell maturation GO:0048469 127 0.015
stem cell differentiation GO:0048863 268 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
response to growth factor GO:0070848 198 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
organelle assembly GO:0070925 177 0.015
regulation of blood circulation GO:1903522 93 0.015
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.015
female gamete generation GO:0007292 74 0.015
cellular amine metabolic process GO:0044106 44 0.015
substantia nigra development GO:0021762 2 0.015
placenta development GO:0001890 140 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
activation of cysteine type endopeptidase activity GO:0097202 27 0.015
dna damage checkpoint GO:0000077 26 0.014
cellular ketone metabolic process GO:0042180 84 0.014
regulation of actin filament based process GO:0032970 99 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
protein processing GO:0016485 163 0.014
double strand break repair GO:0006302 48 0.014
regulation of erk1 and erk2 cascade GO:0070372 71 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
cellular response to organic cyclic compound GO:0071407 87 0.014
negative regulation of protein maturation GO:1903318 79 0.014
dna repair GO:0006281 107 0.014
purine containing compound catabolic process GO:0072523 213 0.014
positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 5 0.014
mitotic cytokinesis GO:0000281 4 0.014
organonitrogen compound catabolic process GO:1901565 264 0.013
midbrain development GO:0030901 35 0.013
muscle system process GO:0003012 141 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
stem cell maintenance GO:0019827 130 0.013
response to lipopolysaccharide GO:0032496 128 0.013
cation transmembrane transport GO:0098655 266 0.013
nucleoside metabolic process GO:0009116 246 0.013
ventricular septum development GO:0003281 42 0.013
centriole assembly GO:0098534 6 0.013
inflammatory response GO:0006954 244 0.013
lipid biosynthetic process GO:0008610 179 0.013
response to transforming growth factor beta GO:0071559 88 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
hair follicle development GO:0001942 85 0.013
regulation of neuron death GO:1901214 134 0.013
b cell differentiation GO:0030183 78 0.013
positive regulation of peptidase activity GO:0010952 49 0.013
lung development GO:0030324 164 0.013
cellular response to lipopolysaccharide GO:0071222 77 0.013
positive regulation of transferase activity GO:0051347 167 0.012
double strand break repair via homologous recombination GO:0000724 21 0.012
cilium morphogenesis GO:0060271 102 0.012
regulation of cellular amino acid metabolic process GO:0006521 5 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903376 3 0.012
apoptotic signaling pathway GO:0097190 306 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
aromatic compound catabolic process GO:0019439 286 0.012
regulation of membrane potential GO:0042391 192 0.012
lymphocyte differentiation GO:0030098 242 0.012
cartilage development GO:0051216 140 0.012
neuron migration GO:0001764 122 0.012
sperm motility GO:0030317 47 0.012
regulation of nuclear division GO:0051783 56 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
axon transport of mitochondrion GO:0019896 2 0.012
neuron death GO:0070997 154 0.012
dna conformation change GO:0071103 37 0.012
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.012
zymogen activation GO:0031638 41 0.012
peptide transport GO:0015833 133 0.012
ribose phosphate metabolic process GO:0019693 291 0.012
nucleotide catabolic process GO:0009166 217 0.011
cell fate specification GO:0001708 72 0.011
synaptic transmission GO:0007268 329 0.011
oocyte axis specification GO:0007309 2 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
regulation of response to cytokine stimulus GO:0060759 23 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
response to alcohol GO:0097305 48 0.011
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.011
cellular response to external stimulus GO:0071496 88 0.011
neural tube development GO:0021915 160 0.011
cerebral cortex development GO:0021987 86 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
homeostasis of number of cells GO:0048872 210 0.011
spindle assembly GO:0051225 13 0.011
forebrain development GO:0030900 302 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
dna templated transcription elongation GO:0006354 13 0.011
neuron intrinsic apoptotic signaling pathway in response to oxidative stress GO:0036480 3 0.011
mitotic cell cycle process GO:1903047 159 0.011
cellular chemical homeostasis GO:0055082 215 0.010
regulation of protein maturation GO:1903317 96 0.010
anatomical structure homeostasis GO:0060249 145 0.010
spindle assembly involved in mitosis GO:0090307 4 0.010
inflammatory response to wounding GO:0090594 4 0.010
regulation of defense response GO:0031347 233 0.010
positive regulation of protein complex assembly GO:0031334 45 0.010
Human
developmental maturation GO:0021700 193 0.010
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.010
cytoplasmic transport GO:0016482 234 0.010
detection of stimulus GO:0051606 84 0.010

Sumo1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
musculoskeletal system disease DOID:17 0 0.012