|
|
positive regulation of t cell mediated cytotoxicity
|
GO:0001916 |
15 |
1.000
|
|
|
|
negative regulation of natural killer cell mediated immunity
|
GO:0002716 |
5 |
1.000
|
Rat |
|
|
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway
|
GO:0002484 |
3 |
0.997
|
|
|
|
antigen processing and presentation of exogenous peptide antigen
|
GO:0002478 |
21 |
0.977
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.954
|
|
|
|
regulation of t cell mediated cytotoxicity
|
GO:0001914 |
18 |
0.945
|
|
|
|
myosin filament organization
|
GO:0031033 |
3 |
0.940
|
Worm |
|
|
antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway
|
GO:0002488 |
2 |
0.929
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.921
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.911
|
|
|
|
antigen processing and presentation of exogenous antigen
|
GO:0019884 |
26 |
0.896
|
|
|
|
regulation of myd88 independent toll like receptor signaling pathway
|
GO:0034127 |
1 |
0.869
|
|
|
|
antigen processing and presentation of peptide antigen via mhc class ib
|
GO:0002428 |
5 |
0.864
|
|
|
|
antigen processing and presentation of endogenous peptide antigen
|
GO:0002483 |
6 |
0.863
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.861
|
Rat |
|
|
regulation of natural killer cell mediated immunity
|
GO:0002715 |
19 |
0.858
|
Rat |
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
19 |
0.855
|
Rat |
|
|
antigen processing and presentation of peptide antigen via mhc class i
|
GO:0002474 |
9 |
0.839
|
|
|
|
antigen processing and presentation of peptide antigen
|
GO:0048002 |
29 |
0.834
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.832
|
Human |
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.821
|
Worm |
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.792
|
Rat |
|
|
iron ion import into cell
|
GO:0097459 |
4 |
0.788
|
|
|
|
antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway tap dependent
|
GO:0002489 |
2 |
0.760
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.757
|
Rat |
|
|
antigen processing and presentation of endogenous peptide antigen via mhc class ib
|
GO:0002476 |
4 |
0.728
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.725
|
Rat |
|
|
antigen processing and presentation of exogenous peptide antigen via mhc class i
|
GO:0042590 |
6 |
0.717
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.657
|
Rat |
|
|
t cell activation
|
GO:0042110 |
289 |
0.611
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.603
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.569
|
Human |
|
|
antigen processing and presentation via mhc class ib
|
GO:0002475 |
8 |
0.550
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
17 |
0.526
|
Rat |
|
|
antigen processing and presentation of exogenous peptide antigen via mhc class ib
|
GO:0002477 |
3 |
0.516
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.505
|
Rat |
|
|
antigen processing and presentation of endogenous peptide antigen via mhc class i
|
GO:0019885 |
3 |
0.497
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.496
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.480
|
Worm |
|
|
regulation of type i interferon mediated signaling pathway
|
GO:0060338 |
7 |
0.447
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.402
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
1 |
0.400
|
Worm |
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.399
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.387
|
Rat |
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.361
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.359
|
|
|
|
regulation of myd88 dependent toll like receptor signaling pathway
|
GO:0034124 |
2 |
0.353
|
|
|
|
transition metal ion transport
|
GO:0000041 |
38 |
0.348
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.328
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.321
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
80 |
0.311
|
Human |
|
|
viral life cycle
|
GO:0019058 |
36 |
0.299
|
Human |
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.290
|
|
|
|
cd8 positive alpha beta t cell proliferation
|
GO:0035740 |
1 |
0.289
|
|
|
|
rna interference
|
GO:0016246 |
2 |
0.281
|
Worm |
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.276
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.270
|
Human |
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.253
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.251
|
Worm |
|
|
positive regulation of t cell mediated immunity
|
GO:0002711 |
24 |
0.244
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.243
|
|
|
|
positive regulation of tolerance induction dependent upon immune response
|
GO:0002654 |
1 |
0.243
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.241
|
Human |
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.230
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.227
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.224
|
|
|
|
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway tap dependent
|
GO:0002485 |
3 |
0.222
|
|
|
|
t helper 17 cell lineage commitment
|
GO:0072540 |
4 |
0.220
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.218
|
|
|
|
intracellular transport of virus
|
GO:0075733 |
1 |
0.218
|
Human |
|
|
negative regulation of interferon beta biosynthetic process
|
GO:0045358 |
1 |
0.217
|
|
|
|
antigen processing and presentation of endogenous antigen
|
GO:0019883 |
6 |
0.203
|
|
|
|
iron ion import
|
GO:0097286 |
5 |
0.198
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.183
|
Human |
|
|
gland development
|
GO:0048732 |
330 |
0.173
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.173
|
|
|
|
atp metabolic process
|
GO:0046034 |
75 |
0.173
|
Human |
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.168
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.167
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.164
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.159
|
Worm |
|
|
negative regulation of interferon beta production
|
GO:0032688 |
3 |
0.158
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.157
|
Worm |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.156
|
Human |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.155
|
Human |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.153
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.152
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.151
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.148
|
Human |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.147
|
Human |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.145
|
Human |
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.145
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.141
|
Worm |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.138
|
Human |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.135
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.132
|
Human |
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.132
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.130
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.127
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.126
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.125
|
Human |
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.123
|
Rat |
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.120
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.119
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.117
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.117
|
Worm |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.116
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.115
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.115
|
Human |
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.111
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.110
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
8 |
0.107
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.106
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.106
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.106
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.105
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
58 |
0.103
|
Human |
|
|
negative regulation of defense response to virus by host
|
GO:0050689 |
1 |
0.102
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.099
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.099
|
|
|
|
atp catabolic process
|
GO:0006200 |
55 |
0.099
|
Human |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.098
|
Human |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.098
|
Worm |
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.097
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.097
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.095
|
Human |
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.093
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.092
|
Human |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.092
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.091
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.090
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.090
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.088
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.088
|
|
|
|
interleukin 12 biosynthetic process
|
GO:0042090 |
8 |
0.088
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.088
|
Human |
|
|
tolerance induction dependent upon immune response
|
GO:0002461 |
1 |
0.087
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.085
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
81 |
0.084
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.084
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.083
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.083
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.082
|
Human |
|
|
regulation of tolerance induction dependent upon immune response
|
GO:0002652 |
1 |
0.081
|
|
|
|
myofibril assembly
|
GO:0030239 |
34 |
0.081
|
Worm |
|
|
iron ion homeostasis
|
GO:0055072 |
36 |
0.081
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.080
|
|
|
|
negative regulation of lymphocyte mediated immunity
|
GO:0002707 |
21 |
0.079
|
Rat |
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.078
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
10 |
0.075
|
Worm |
|
|
cation transport
|
GO:0006812 |
399 |
0.075
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.075
|
|
|
|
response to type i interferon
|
GO:0034340 |
12 |
0.074
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.073
|
Human |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.073
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
59 |
0.071
|
Human |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.069
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.069
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.069
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
57 |
0.069
|
Human |
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.067
|
|
|
|
positive regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060261 |
5 |
0.067
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.067
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.066
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.066
|
Human |
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.066
|
Human |
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.066
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.065
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.065
|
|
|
|
interleukin 4 mediated signaling pathway
|
GO:0035771 |
2 |
0.063
|
|
|
|
peptidyl lysine methylation
|
GO:0018022 |
29 |
0.063
|
|
|
|
positive regulation of type i interferon mediated signaling pathway
|
GO:0060340 |
4 |
0.063
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.062
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.062
|
Human |
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.061
|
|
|
|
lysosomal transport
|
GO:0007041 |
10 |
0.061
|
Worm |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.061
|
|
|
|
transport of virus
|
GO:0046794 |
1 |
0.060
|
Human |
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.060
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.059
|
|
|
|
regulation of cd8 positive alpha beta t cell activation
|
GO:2001185 |
3 |
0.059
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.058
|
Human Rat |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.058
|
|
|
|
alpha beta t cell lineage commitment
|
GO:0002363 |
7 |
0.058
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.057
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.056
|
Human |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.056
|
Human |
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.055
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.053
|
Human |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.052
|
|
|
|
regulation of mast cell differentiation
|
GO:0060375 |
3 |
0.050
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.050
|
Rat |
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.050
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.050
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.049
|
|
|
|
antigen processing and presentation of exogenous protein antigen via mhc class ib tap dependent
|
GO:0002481 |
3 |
0.049
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.049
|
Human |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.048
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.048
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.048
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.047
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.047
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.046
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.046
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.046
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.044
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.044
|
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.044
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.044
|
Human |
|
|
regulation of interleukin 12 biosynthetic process
|
GO:0045075 |
8 |
0.043
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.043
|
Human |
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.043
|
Human |
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.042
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.042
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.042
|
Human |
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.041
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.040
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.040
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.040
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.040
|
|
|
|
marginal zone b cell differentiation
|
GO:0002315 |
2 |
0.040
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.040
|
|
|
|
dna templated transcription initiation
|
GO:0006352 |
13 |
0.040
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.039
|
Worm |
|
|
regulation of actin nucleation
|
GO:0051125 |
4 |
0.039
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.039
|
|
|
|
growth of symbiont involved in interaction with host
|
GO:0044116 |
23 |
0.039
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.039
|
|
|
|
regulation of dna templated transcription initiation
|
GO:2000142 |
7 |
0.038
|
|
|
|
positive regulation of response to cytokine stimulus
|
GO:0060760 |
11 |
0.038
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.037
|
|
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
5 |
0.037
|
|
|
|
negative regulation of regulatory t cell differentiation
|
GO:0045590 |
2 |
0.037
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.036
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.036
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.036
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.036
|
Human |
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.035
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.035
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.035
|
|
|
|
positive regulation of natural killer cell mediated cytotoxicity
|
GO:0045954 |
16 |
0.035
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.035
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.034
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.034
|
|
|
|
negative regulation of glycolytic process
|
GO:0045820 |
4 |
0.034
|
|
|
|
positive regulation of actin nucleation
|
GO:0051127 |
3 |
0.034
|
|
|
|
response to protozoan
|
GO:0001562 |
28 |
0.034
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.034
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.034
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.033
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.033
|
|
|
|
cd8 positive alpha beta t cell differentiation
|
GO:0043374 |
9 |
0.033
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.033
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.033
|
Worm |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.033
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.033
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.033
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.032
|
|
|
|
t helper 1 cell lineage commitment
|
GO:0002296 |
2 |
0.031
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.031
|
|
|
|
negative regulation of cytokine biosynthetic process
|
GO:0042036 |
13 |
0.031
|
|
|
|
t helper 17 cell differentiation
|
GO:0072539 |
7 |
0.031
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.031
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.031
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.030
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.030
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.030
|
|
|
|
import into cell
|
GO:0098657 |
8 |
0.030
|
|
|
|
inorganic cation import into cell
|
GO:0098659 |
4 |
0.030
|
|
|
|
regulation of nitric oxide biosynthetic process
|
GO:0045428 |
18 |
0.030
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.029
|
|
|
|
response to interleukin 2
|
GO:0070669 |
2 |
0.029
|
|
|
|
isoleucine metabolic process
|
GO:0006549 |
4 |
0.029
|
|
|
|
citrate metabolic process
|
GO:0006101 |
3 |
0.029
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.028
|
|
|
|
positive regulation of mast cell differentiation
|
GO:0060376 |
1 |
0.028
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.028
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.028
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.028
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.028
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.028
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.028
|
Human |
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
8 |
0.028
|
|
|
|
negative regulation of natural killer cell mediated cytotoxicity
|
GO:0045953 |
5 |
0.027
|
Rat |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.027
|
|
|
|
viral process
|
GO:0016032 |
41 |
0.027
|
Human |
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.027
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.027
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.027
|
|
|
|
positive regulation of type i interferon production
|
GO:0032481 |
14 |
0.027
|
|
|
|
t helper 17 type immune response
|
GO:0072538 |
9 |
0.027
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.026
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.026
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.026
|
|
|
|
keratinocyte proliferation
|
GO:0043616 |
21 |
0.026
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.026
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.025
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.025
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.025
|
Human |
|
|
stem cell development
|
GO:0048864 |
219 |
0.025
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.025
|
Human |
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.025
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.024
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.024
|
|
|
|
negative regulation of cell killing
|
GO:0031342 |
8 |
0.023
|
Rat |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.023
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.023
|
|
|
|
positive regulation of mast cell proliferation
|
GO:0070668 |
3 |
0.023
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.023
|
|
|
|
female gonad development
|
GO:0008585 |
71 |
0.023
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.023
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.023
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.023
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.023
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.023
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.023
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.022
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.022
|
Human |
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.022
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.022
|
|
|
|
inorganic ion import into cell
|
GO:0099587 |
4 |
0.022
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.022
|
Human Rat |
|
|
regulation of cd8 positive alpha beta t cell proliferation
|
GO:2000564 |
1 |
0.022
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.022
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.022
|
|
|
|
hormone biosynthetic process
|
GO:0042446 |
16 |
0.021
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.021
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.021
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.021
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.021
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.021
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.021
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.021
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.021
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.020
|
|
|
|
gene silencing by rna
|
GO:0031047 |
19 |
0.020
|
Worm |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.020
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.020
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.020
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.020
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.020
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.020
|
|
|
|
iron ion transport
|
GO:0006826 |
17 |
0.020
|
|
|
|
face morphogenesis
|
GO:0060325 |
29 |
0.020
|
|
|
|
creatinine metabolic process
|
GO:0046449 |
3 |
0.020
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.019
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.019
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.019
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.019
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.019
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
30 |
0.019
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.019
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.019
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.019
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.019
|
|
|
|
macrophage fusion
|
GO:0034238 |
3 |
0.019
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.019
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.019
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.019
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.019
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.019
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.019
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.018
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.018
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
52 |
0.018
|
|
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.018
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.018
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
57 |
0.018
|
Human |
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.018
|
|
|
|
response to interleukin 15
|
GO:0070672 |
3 |
0.018
|
|
|
|
t cell lineage commitment
|
GO:0002360 |
13 |
0.018
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.018
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.018
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.018
|
|
|
|
interaction with host
|
GO:0051701 |
22 |
0.018
|
Human |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.018
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.018
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.018
|
|
|
|
mammary gland epithelial cell differentiation
|
GO:0060644 |
13 |
0.018
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.017
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.017
|
Human |
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.017
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.017
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.017
|
|
|
|
positive regulation of dna templated transcription initiation
|
GO:2000144 |
5 |
0.017
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.017
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.017
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.017
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.017
|
Human |
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.017
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.017
|
|
|
|
progesterone metabolic process
|
GO:0042448 |
4 |
0.017
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.017
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.017
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.017
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.017
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.016
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.016
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.016
|
|
|
|
type i interferon production
|
GO:0032606 |
29 |
0.016
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.016
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.016
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.016
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.016
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.016
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.016
|
Human |
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.016
|
Human |
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.016
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.016
|
|
|
|
regulation of interleukin 5 secretion
|
GO:2000662 |
2 |
0.015
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.015
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.015
|
Human |
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.015
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.015
|
Human |
|
|
epinephrine secretion
|
GO:0048242 |
1 |
0.015
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.015
|
|
|
|
multicellular organismal iron ion homeostasis
|
GO:0060586 |
8 |
0.015
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.015
|
|
|
|
positive regulation of rig i signaling pathway
|
GO:1900246 |
1 |
0.015
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.015
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.015
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.015
|
|
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
11 |
0.015
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.015
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.015
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.015
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.015
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.015
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.015
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.015
|
|
|
|
t cell tolerance induction
|
GO:0002517 |
6 |
0.015
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.015
|
|
|
|
regulation of macrophage fusion
|
GO:0034239 |
3 |
0.014
|
|
|
|
t cell antigen processing and presentation
|
GO:0002457 |
2 |
0.014
|
|
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.014
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.014
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.014
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.014
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.014
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.014
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.014
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.014
|
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
25 |
0.014
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.014
|
|
|
|
prostate gland development
|
GO:0030850 |
48 |
0.014
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.014
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.014
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.014
|
|
|
|
myd88 dependent toll like receptor signaling pathway
|
GO:0002755 |
7 |
0.014
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.014
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.014
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.014
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.014
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.014
|
|
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.014
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.014
|
|
|
|
response to dsrna
|
GO:0043331 |
30 |
0.014
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.014
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.014
|
|
|
|
regulation of antimicrobial peptide production
|
GO:0002784 |
1 |
0.014
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.013
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.013
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.013
|
|
|
|
gene silencing by mirna
|
GO:0035195 |
10 |
0.013
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.013
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.013
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.013
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.013
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.013
|
|
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.013
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.013
|
|
|
|
interleukin 5 secretion
|
GO:0072603 |
2 |
0.013
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.013
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.013
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.013
|
|
|
|
t cell homeostasis
|
GO:0043029 |
35 |
0.013
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.013
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.013
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.013
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.012
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.012
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.012
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.012
|
|
|
|
cerebral cortex tangential migration using cell axon interactions
|
GO:0021824 |
3 |
0.012
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.012
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.012
|
|
