|
|
t cell differentiation
|
GO:0030217 |
174 |
0.795
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.773
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.732
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.732
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.706
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.682
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.679
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.647
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.603
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.590
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.547
|
Mouse |
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.501
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.497
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.480
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.462
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.445
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.424
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.423
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.404
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.389
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.388
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.374
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.368
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.359
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.358
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.354
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.353
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.353
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.352
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.341
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.331
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.330
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.325
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.323
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.312
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.307
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.305
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.304
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.303
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.303
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.300
|
|
|
|
lymphocyte costimulation
|
GO:0031294 |
15 |
0.289
|
|
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.287
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.281
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.281
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.275
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.266
|
Mouse |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.260
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.256
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.254
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.248
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.247
|
Mouse |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.244
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.239
|
Mouse |
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.238
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.237
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.237
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.236
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.236
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.235
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.234
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.232
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.231
|
Mouse |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.229
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.226
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.219
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.214
|
Mouse |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.211
|
Mouse |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.208
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.202
|
Mouse |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.200
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.198
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.196
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.192
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.191
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.187
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.185
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.183
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.182
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.181
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.179
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.178
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.176
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.176
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.176
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.173
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.172
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.170
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.169
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.166
|
Mouse |
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.163
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.154
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.151
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.149
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.149
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.147
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.144
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.143
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.143
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.141
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.138
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.138
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.136
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.135
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.134
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.134
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.133
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.124
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.123
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.122
|
Mouse |
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.122
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.117
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.116
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.116
|
Mouse |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.115
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.114
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.114
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.112
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.111
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.111
|
Mouse |
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.111
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.110
|
|
|
|
regulation of interleukin 4 biosynthetic process
|
GO:0045402 |
3 |
0.109
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.109
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.109
|
Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.109
|
Mouse |
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.108
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.108
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.107
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.107
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.105
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.105
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.105
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.104
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.104
|
Mouse |
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.104
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.104
|
Mouse |
|
|
innate immune response
|
GO:0045087 |
157 |
0.104
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.103
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.103
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.102
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.102
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.101
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.101
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.099
|
|
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
6 |
0.099
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.099
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.098
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.097
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.097
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.097
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.097
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
47 |
0.096
|
Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.095
|
Mouse |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.093
|
Mouse |
|
|
regulation of natural killer cell mediated immunity
|
GO:0002715 |
19 |
0.093
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.092
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.092
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.092
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.092
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.091
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.090
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.090
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
34 |
0.090
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.089
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.089
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.089
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.088
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.088
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.088
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.088
|
Mouse |
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.087
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.087
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.087
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.086
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.086
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.086
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.086
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.085
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.085
|
Mouse |
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.085
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.085
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.085
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.084
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.084
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.084
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.081
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.081
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.081
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.081
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.080
|
Mouse |
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.080
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.080
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.079
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.079
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.078
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.078
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.078
|
Mouse |
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
31 |
0.077
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.076
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.076
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.076
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.075
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.075
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.075
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.074
|
Mouse |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.073
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.073
|
Mouse |
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.072
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.072
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.072
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.071
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.070
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.070
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.070
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.070
|
|
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.069
|
Mouse |
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.069
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.069
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.068
|
Mouse |
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.068
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.068
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.068
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.067
|
Mouse |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.067
|
|
|
|
eosinophil migration
|
GO:0072677 |
3 |
0.067
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.067
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.066
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.066
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.065
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.065
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.065
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.064
|
Mouse |
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.064
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.063
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.062
|
Mouse |
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.062
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.062
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.062
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.061
|
Mouse |
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.061
|
Mouse |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.060
|
|
|
|
interleukin 2 secretion
|
GO:0070970 |
7 |
0.060
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.060
|
Mouse |
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.060
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.060
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.059
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.059
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.059
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.059
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.059
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.059
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.059
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.058
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.058
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.058
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.058
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.058
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.057
|
Mouse |
|
|
chromatin modification
|
GO:0016568 |
187 |
0.057
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.057
|
Mouse |
|
|
ossification
|
GO:0001503 |
216 |
0.057
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.056
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.056
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.056
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.056
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.055
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.055
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.055
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.054
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.054
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.054
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.054
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.054
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.054
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.053
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.053
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.053
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.053
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.053
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.052
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.052
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.052
|
Mouse |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.052
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.052
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.052
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.052
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.051
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.051
|
|
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.051
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.051
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.051
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.051
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.051
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.051
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.050
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.050
|
|
|
|
negative regulation of growth of symbiont involved in interaction with host
|
GO:0044146 |
19 |
0.050
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.050
|
|
|
|
negative regulation of interleukin 2 biosynthetic process
|
GO:0045085 |
3 |
0.050
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.050
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.050
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.050
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
16 |
0.049
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.049
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.048
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.048
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.048
|
Mouse |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.048
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.047
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.047
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.047
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.047
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.047
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.047
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
22 |
0.047
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.047
|
Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.046
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.046
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.046
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.046
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.046
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.046
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.046
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.045
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.045
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.045
|
|
|
|
negative regulation of rho protein signal transduction
|
GO:0035024 |
7 |
0.045
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.045
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.045
|
Mouse |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.045
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.045
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.045
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.044
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.044
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.044
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.044
|
Mouse |
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.044
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.044
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.043
|
Mouse |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.043
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.043
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
16 |
0.043
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.043
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.043
|
|
|
|
positive regulation of eosinophil migration
|
GO:2000418 |
2 |
0.043
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.042
|
Mouse |
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.042
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.042
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.042
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.042
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.042
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.042
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.041
|
|
|
|
blastocyst growth
|
GO:0001832 |
23 |
0.041
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.041
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
21 |
0.041
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.041
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.040
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.040
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.040
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.040
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.040
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.040
|
Mouse |
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.040
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.040
|
Mouse |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.040
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.039
|
|
|
|
negative regulation of myeloid dendritic cell activation
|
GO:0030886 |
3 |
0.039
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.039
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.039
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.039
|
Mouse |
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.039
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.039
|
Mouse |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.038
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.038
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.038
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.038
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.038
|
Mouse |
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.037
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.037
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.037
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.037
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.037
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.037
|
Mouse |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.037
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.037
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.037
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.037
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.036
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.036
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.036
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.036
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.036
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.036
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.036
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.036
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.036
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.036
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.036
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.035
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.035
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.035
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.035
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.035
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.035
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.035
|
|
|
|
response to interleukin 4
|
GO:0070670 |
23 |
0.035
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.035
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.035
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.034
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.034
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.034
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.034
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.034
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.034
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.034
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.033
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.033
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.033
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.033
|
|
|
|
negative regulation of interleukin 2 production
|
GO:0032703 |
8 |
0.033
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.032
|
Mouse |
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.032
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.032
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.032
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.032
|
|
|
|
regulation of eosinophil migration
|
GO:2000416 |
2 |
0.032
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.032
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.032
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.032
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.032
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.032
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.032
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.031
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.031
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.031
|
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
4 |
0.031
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.031
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.031
|
|
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.031
|
|
|
|
mrna transcription from rna polymerase ii promoter
|
GO:0042789 |
4 |
0.031
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.031
|
Mouse |
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
19 |
0.031
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.031
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.030
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.030
|
|
|
|
negative regulation of interferon gamma production
|
GO:0032689 |
18 |
0.030
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.030
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.030
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
34 |
0.030
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.030
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.030
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.029
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.029
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
57 |
0.029
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.029
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.029
|
|
|
|
inner cell mass cell proliferation
|
GO:0001833 |
15 |
0.029
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.029
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.029
|
Mouse |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.029
|
|
|
|
osteoblast development
|
GO:0002076 |
17 |
0.029
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.029
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
36 |
0.028
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
30 |
0.028
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.028
|
Mouse |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.028
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.028
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.028
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.028
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.028
|
|
|
|
forelimb morphogenesis
|
GO:0035136 |
40 |
0.028
|
Mouse |
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.028
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.028
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.028
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.028
|
Mouse |
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.028
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.027
|
Mouse |
|
|
mammary gland duct morphogenesis
|
GO:0060603 |
38 |
0.027
|
Mouse |
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.027
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.027
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.027
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.027
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.027
|
Mouse |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.027
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.027
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.027
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.027
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.027
|
Mouse |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.027
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.027
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.027
|
Mouse |
|
|
growth of symbiont involved in interaction with host
|
GO:0044116 |
23 |
0.027
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.027
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.027
|
Mouse |
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.027
|
|
