|
|
defense response to other organism
|
GO:0098542 |
197 |
0.717
|
Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.658
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.602
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.580
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.559
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.479
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.437
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.415
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.403
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.398
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.391
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.375
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.369
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.363
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.355
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.352
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.352
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.347
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.332
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.325
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.322
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.298
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.292
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.283
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.282
|
Fly |
|
|
membrane organization
|
GO:0061024 |
245 |
0.282
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.265
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.265
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.261
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.258
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.253
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.253
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.251
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.243
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.242
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.241
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.240
|
|
|
|
unsaturated fatty acid biosynthetic process
|
GO:0006636 |
15 |
0.239
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.238
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.235
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.235
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.234
|
Fly |
|
|
t cell activation
|
GO:0042110 |
289 |
0.233
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.231
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.231
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.229
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.229
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.227
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.221
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.217
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.217
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.215
|
|
|
|
serotonin transport
|
GO:0006837 |
11 |
0.213
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.210
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.206
|
Fly |
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.205
|
|
|
|
positive regulation of dendritic cell dendrite assembly
|
GO:2000549 |
1 |
0.203
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.200
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.188
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.188
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.186
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.178
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.173
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.173
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.172
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.170
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.170
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.168
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.168
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.166
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.162
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.161
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.160
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.158
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.156
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.153
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.151
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.145
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.143
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.143
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.143
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.143
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.142
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.142
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.141
|
|
|
|
purinergic nucleotide receptor signaling pathway
|
GO:0035590 |
3 |
0.141
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.136
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.133
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.128
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.127
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.126
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.126
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.126
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.123
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.123
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.123
|
|
|
|
eosinophil migration
|
GO:0072677 |
3 |
0.122
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.121
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.121
|
Fly |
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.120
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.120
|
|
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
2 |
0.120
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.119
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.119
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.119
|
Fly |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.116
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.116
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.115
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.114
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.114
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.110
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.110
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.108
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.108
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.108
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.107
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.107
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.107
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.106
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.105
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
15 |
0.105
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.104
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.104
|
|
|
|
regulation of t helper 2 cell cytokine production
|
GO:2000551 |
3 |
0.104
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.103
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.103
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.103
|
|
|
|
regulation of natural killer cell chemotaxis
|
GO:2000501 |
1 |
0.102
|
|
|
|
immunoglobulin production in mucosal tissue
|
GO:0002426 |
3 |
0.101
|
|
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.100
|
|
|
|
neutrophil mediated immunity
|
GO:0002446 |
19 |
0.097
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.096
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.096
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.093
|
Fly |
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.092
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.091
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.091
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.091
|
|
|
|
positive regulation of natural killer cell chemotaxis
|
GO:2000503 |
1 |
0.090
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.089
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.089
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.088
|
|
|
|
serotonin secretion involved in inflammatory response
|
GO:0002442 |
4 |
0.088
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.087
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.087
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.086
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.086
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.083
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.082
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.082
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.081
|
|
|
|
toll like receptor 7 signaling pathway
|
GO:0034154 |
4 |
0.081
|
|
|
|
serotonin production involved in inflammatory response
|
GO:0002351 |
4 |
0.081
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.081
|
|
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.080
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.079
|
|
|
|
cofactor transport
|
GO:0051181 |
4 |
0.078
|
|
|
|
positive regulation of macrophage chemotaxis
|
GO:0010759 |
5 |
0.078
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.078
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.077
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.077
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.075
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.075
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.075
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.075
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.073
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.073
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.072
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.072
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.071
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.071
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.071
|
Fly |
|
|
cell junction organization
|
GO:0034330 |
77 |
0.071
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.071
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.070
|
|
|
|
positive regulation of immunoglobulin production in mucosal tissue
|
GO:2000558 |
1 |
0.070
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.070
|
|
|
|
activation of jun kinase activity
|
GO:0007257 |
15 |
0.070
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.070
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.069
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.069
|
|
|
|
immunoglobulin transcytosis in epithelial cells
|
GO:0002414 |
2 |
0.069
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.068
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.067
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.067
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
18 |
0.067
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.066
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.066
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.065
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.065
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.065
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.065
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.065
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.064
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.063
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.063
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.062
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.062
|
|
|
|
positive regulation of mast cell activation
|
GO:0033005 |
12 |
0.062
|
|
|
|
regulation of toll like receptor 9 signaling pathway
|
GO:0034163 |
3 |
0.062
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.062
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.061
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.061
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.061
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.060
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.060
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.060
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.060
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.060
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.059
|
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045425 |
2 |
0.058
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
14 |
0.058
|
|
|
|
monoamine transport
|
GO:0015844 |
33 |
0.058
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.058
|
|
|
|
icosanoid biosynthetic process
|
GO:0046456 |
15 |
0.058
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.058
|
|
|
|
positive regulation of mast cell degranulation
|
GO:0043306 |
10 |
0.057
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.057
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.057
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.057
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.057
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.057
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.057
|
|
|
|
fatty acid derivative biosynthetic process
|
GO:1901570 |
15 |
0.056
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.056
|
|
|
|
positive regulation of metanephric mesenchymal cell migration
|
GO:2000591 |
1 |
0.056
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.055
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.055
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.055
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.055
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.055
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.055
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.054
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.054
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.054
|
|
|
|
negative regulation of lipoprotein lipase activity
|
GO:0051005 |
1 |
0.053
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.053
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.053
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.052
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.052
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.052
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.051
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.050
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.050
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.050
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.050
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.050
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.050
|
|
|
|
positive regulation of regulated secretory pathway
|
GO:1903307 |
10 |
0.050
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.050
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
20 |
0.049
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.049
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.049
|
|
|
|
digestion
|
GO:0007586 |
40 |
0.049
|
|
|
|
b cell chemotaxis
|
GO:0035754 |
3 |
0.048
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.048
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.048
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.048
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.048
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.048
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.048
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.048
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.048
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.048
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.048
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.047
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.047
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.047
|
|
|
|
positive regulation of thymocyte migration
|
GO:2000412 |
2 |
0.047
|
|
|
|
innate immune response in mucosa
|
GO:0002227 |
3 |
0.047
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.047
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.047
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.047
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.046
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.046
|
Mouse Fly |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.046
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.046
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.046
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.046
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
30 |
0.046
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.045
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.045
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.045
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.045
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.045
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.045
|
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
45 |
0.045
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.045
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.045
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.045
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.045
|
Fly |
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.045
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.045
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.045
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.044
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.044
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.044
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.044
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.044
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.044
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.044
|
|
|
|
negative regulation of mast cell degranulation
|
GO:0043305 |
4 |
0.044
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.044
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.044
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.043
|
|
|
|
mucosal immune response
|
GO:0002385 |
13 |
0.043
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.043
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.043
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.043
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.043
|
Rat |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.043
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.043
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.043
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.042
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.042
|
|
|
|
granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0042253 |
2 |
0.042
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.042
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.041
|
|
|
|
regulation of b cell chemotaxis
|
GO:2000537 |
2 |
0.041
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.041
|
|
|
|
antigen processing and presentation of exogenous peptide antigen
|
GO:0002478 |
21 |
0.041
|
|
|
|
l amino acid transport
|
GO:0015807 |
32 |
0.041
|
|
|
|
positive regulation of mast cell activation involved in immune response
|
GO:0033008 |
10 |
0.041
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.040
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.040
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.040
|
|
|
|
vacuole organization
|
GO:0007033 |
38 |
0.040
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.040
|
|
|
|
purinergic receptor signaling pathway
|
GO:0035587 |
7 |
0.040
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.040
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.040
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.040
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.040
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.039
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.039
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.039
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.039
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.039
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.039
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.039
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.039
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.038
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.038
|
|
|
|
positive regulation of eosinophil migration
|
GO:2000418 |
2 |
0.038
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.038
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.038
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.038
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.038
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
61 |
0.038
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.038
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.038
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.037
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.037
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.037
|
|
|
|
regulation of thymocyte migration
|
GO:2000410 |
2 |
0.037
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.037
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.037
|
Rat |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.037
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.037
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.037
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.037
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.037
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.037
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.037
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.037
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.036
|
|
|
|
serotonin secretion by mast cell
|
GO:0002552 |
1 |
0.036
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.036
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.036
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.036
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.036
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.036
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.036
|
|
|
|
serotonin secretion
|
GO:0001820 |
8 |
0.035
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.035
|
|
|
|
defense response to fungus
|
GO:0050832 |
12 |
0.035
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.035
|
|
|
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.035
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.035
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.035
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.035
|
|
|
|
astrocyte cell migration
|
GO:0043615 |
3 |
0.035
|
|
|
|
ceramide metabolic process
|
GO:0006672 |
31 |
0.035
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.034
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.034
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.034
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
35 |
0.034
|
|
|
|
icosanoid metabolic process
|
GO:0006690 |
33 |
0.034
|
|
|
|
negative regulation of hypersensitivity
|
GO:0002884 |
3 |
0.034
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.034
|
|
|
|
amino acid transport
|
GO:0006865 |
61 |
0.034
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.033
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.033
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.033
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.033
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.033
|
|
|
|
positive regulation of toll like receptor 9 signaling pathway
|
GO:0034165 |
2 |
0.033
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.033
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.033
|
|
|
|
regulation of immunoglobulin production in mucosal tissue
|
GO:2000557 |
1 |
0.033
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.033
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.033
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.033
|
|
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.033
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.033
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.032
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
3 |
0.032
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.032
|
|
|
|
positive regulation of tumor necrosis factor biosynthetic process
|
GO:0042535 |
8 |
0.032
|
|
|
|
positive regulation of t helper 2 cell cytokine production
|
GO:2000553 |
3 |
0.032
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.032
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.032
|
|
|
|
interleukin 11 mediated signaling pathway
|
GO:0038154 |
2 |
0.032
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.031
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.031
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.031
|
|
|
|
fc epsilon receptor signaling pathway
|
GO:0038095 |
3 |
0.031
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.031
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.031
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.031
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.031
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.031
|
|
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
32 |
0.031
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.031
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.030
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.030
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
17 |
0.030
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.030
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.030
|
|
|
|
antigen processing and presentation of exogenous peptide antigen via mhc class ii
|
GO:0019886 |
14 |
0.030
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.030
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.030
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.030
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.030
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.030
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.030
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.030
|
|
|
|
unsaturated fatty acid metabolic process
|
GO:0033559 |
31 |
0.030
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.030
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.030
|
|
|
|
phagolysosome assembly
|
GO:0001845 |
3 |
0.029
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.029
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
2 |
0.029
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.029
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.029
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.029
|
|
|
|
histamine transport
|
GO:0051608 |
2 |
0.029
|
|
|
|
leukotriene metabolic process
|
GO:0006691 |
7 |
0.029
|
|
|
|
regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045423 |
2 |
0.029
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.029
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.029
|
Rat |
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.029
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.028
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.028
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.028
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.028
|
Fly |
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.028
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.028
|
|
|
|
regulation of chemokine secretion
|
GO:0090196 |
4 |
0.028
|
|
|
|
interaction with symbiont
|
GO:0051702 |
14 |
0.028
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.028
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.027
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.027
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.027
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.027
|
|
|
|
keratinocyte migration
|
GO:0051546 |
3 |
0.027
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.027
|
|
|
|
macrophage chemotaxis
|
GO:0048246 |
14 |
0.027
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.027
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.027
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.026
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.026
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.026
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.026
|
|
|
|
positive regulation of leukocyte degranulation
|
GO:0043302 |
10 |
0.026
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.026
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.026
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.026
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.026
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.026
|
|
|
|
thymocyte migration
|
GO:0072679 |
2 |
0.026
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.026
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.026
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.025
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.025
|
|
|
|
positive regulation of adiponectin secretion
|
GO:0070165 |
1 |
0.025
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.025
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.025
|
|
|
|
interleukin 1 secretion
|
GO:0050701 |
16 |
0.025
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.025
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.025
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.025
|
Rat |
