|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.993
|
Fly |
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.971
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.969
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.968
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.963
|
Human |
|
|
chromatin modification
|
GO:0016568 |
187 |
0.947
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.942
|
Human |
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.942
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.918
|
Human |
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.913
|
|
|
|
oligodendrocyte development
|
GO:0014003 |
20 |
0.910
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.902
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.887
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.881
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.880
|
Zebrafish |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.879
|
Human |
|
|
negative regulation of osteoblast differentiation
|
GO:0045668 |
30 |
0.866
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.860
|
Human |
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.848
|
|
|
|
peyer s patch development
|
GO:0048541 |
12 |
0.838
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.837
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.822
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.820
|
Human Worm Fly |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.813
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.805
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.804
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
36 |
0.772
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.735
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.728
|
|
|
|
regulation of myoblast differentiation
|
GO:0045661 |
29 |
0.711
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.700
|
|
|
|
natural killer cell differentiation
|
GO:0001779 |
21 |
0.687
|
|
|
|
mucosal associated lymphoid tissue development
|
GO:0048537 |
12 |
0.663
|
|
|
|
regulation of dna binding
|
GO:0051101 |
39 |
0.656
|
|
|
|
epithelial cell differentiation involved in mammary gland alveolus development
|
GO:0061030 |
4 |
0.654
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.654
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.648
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.631
|
Worm |
|
|
regulation of cell cycle arrest
|
GO:0071156 |
12 |
0.631
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.628
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.623
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.620
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.615
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.604
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.599
|
|
|
|
negative regulation of dna binding
|
GO:0043392 |
20 |
0.595
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.587
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.586
|
Human |
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.581
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.576
|
|
|
|
regulation of exit from mitosis
|
GO:0007096 |
1 |
0.568
|
|
|
|
bundle of his development
|
GO:0003166 |
4 |
0.568
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.561
|
Human |
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.560
|
|
|
|
inter male aggressive behavior
|
GO:0002121 |
3 |
0.555
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.549
|
Human |
|
|
midgut development
|
GO:0007494 |
4 |
0.541
|
|
|
|
negative regulation of neural precursor cell proliferation
|
GO:2000178 |
18 |
0.541
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.540
|
Zebrafish |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.539
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.538
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.530
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.526
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.524
|
|
|
|
limbic system development
|
GO:0021761 |
72 |
0.516
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.513
|
Human |
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.513
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.510
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.508
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.498
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.485
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.478
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.472
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
41 |
0.467
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.462
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.458
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.454
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.453
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.450
|
|
|
|
negative regulation of myoblast differentiation
|
GO:0045662 |
18 |
0.446
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.442
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.440
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.436
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.431
|
Human |
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.418
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.417
|
|
|
|
positive regulation of erythrocyte differentiation
|
GO:0045648 |
11 |
0.414
|
|
|
|
positive regulation of exit from mitosis
|
GO:0031536 |
1 |
0.405
|
|
|
|
cellular senescence
|
GO:0090398 |
11 |
0.399
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.396
|
|
|
|
photoreceptor cell fate commitment
|
GO:0046552 |
2 |
0.393
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.390
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.382
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.377
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.376
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
35 |
0.375
|
|
|
|
regulation of mitosis
|
GO:0007088 |
29 |
0.372
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.367
|
|
|
|
positive regulation of translational initiation
|
GO:0045948 |
4 |
0.364
|
|
|
|
cell cycle arrest
|
GO:0007050 |
37 |
0.362
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.359
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.358
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.350
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.348
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.347
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.342
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.342
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.341
|
|
|
|
lung vasculature development
|
GO:0060426 |
7 |
0.339
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.337
|
Human |
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.336
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.328
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.326
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.324
|
|
|
|
locomotor rhythm
|
GO:0045475 |
8 |
0.322
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
14 |
0.322
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.317
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.314
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.309
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.308
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.306
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.303
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.300
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.292
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.291
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
26 |
0.288
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
15 |
0.286
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.281
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.280
|
Human |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.278
|
|
|
|
auditory receptor cell fate determination
|
GO:0042668 |
3 |
0.278
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.276
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.276
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.275
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.273
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.271
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.268
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.268
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.265
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.265
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.265
|
|
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.263
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
45 |
0.263
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.262
|
|
|
|
transdifferentiation
|
GO:0060290 |
1 |
0.261
|
|
|
|
positive regulation of translational initiation by iron
|
GO:0045994 |
2 |
0.261
|
|
|
|
his purkinje system development
|
GO:0003164 |
4 |
0.259
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.252
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.249
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
70 |
0.247
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.245
|
|
|
|
retinal cell programmed cell death
|
GO:0046666 |
8 |
0.244
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.244
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
10 |
0.242
|
|
|
|
positive regulation of macrophage differentiation
|
GO:0045651 |
5 |
0.239
|
|
|
|
intracellular distribution of mitochondria
|
GO:0048312 |
1 |
0.238
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.233
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.230
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.228
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.228
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.228
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
41 |
0.227
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.227
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.225
|
|
|
|
negative regulation of type b pancreatic cell apoptotic process
|
GO:2000675 |
3 |
0.224
|
|
|
|
cell aging
|
GO:0007569 |
35 |
0.219
|
|
|
|
mammary gland alveolus development
|
GO:0060749 |
22 |
0.218
|
|
|
|
hippocampus development
|
GO:0021766 |
52 |
0.212
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
49 |
0.211
|
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
8 |
0.207
|
Mouse |
|
|
neutrophil differentiation
|
GO:0030223 |
3 |
0.207
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.205
|
|
|
|
cardiac right ventricle formation
|
GO:0003219 |
3 |
0.205
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.205
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.200
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.199
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.199
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.199
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
35 |
0.198
|
Human |
|
|
regulation of epidermis development
|
GO:0045682 |
33 |
0.198
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.198
|
|
|
|
multicellular organismal macromolecule metabolic process
|
GO:0044259 |
19 |
0.197
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.196
|
|
|
|
regulation of intestinal epithelial structure maintenance
|
GO:0060730 |
1 |
0.196
|
|
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.196
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.195
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.195
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.195
|
|
|
|
protein alkylation
|
GO:0008213 |
81 |
0.194
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.194
|
|
|
|
mammary gland epithelial cell proliferation
|
GO:0033598 |
24 |
0.193
|
|
|
|
endothelial cell morphogenesis
|
GO:0001886 |
9 |
0.192
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.191
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.188
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.187
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.186
|
|
|
|
lung morphogenesis
|
GO:0060425 |
50 |
0.186
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.185
|
Worm |
|
|
positive regulation of myoblast differentiation
|
GO:0045663 |
8 |
0.183
|
|
|
|
regulation of neutrophil differentiation
|
GO:0045658 |
2 |
0.182
|
|
|
|
negative regulation of binding
|
GO:0051100 |
39 |
0.181
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.179
|
|
|
|
membranous septum morphogenesis
|
GO:0003149 |
6 |
0.178
|
|
|
|
myoblast differentiation
|
GO:0045445 |
52 |
0.177
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.176
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.176
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.175
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.175
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.175
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.174
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.172
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.171
|
|
|
|
cardiac septum morphogenesis
|
GO:0060411 |
46 |
0.170
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.169
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.168
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.167
|
|
|
|
pancreatic pp cell differentiation
|
GO:0003312 |
2 |
0.167
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.166
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
31 |
0.164
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.163
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.163
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.162
|
Human |
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.162
|
|
|
|
regulation of oxidative phosphorylation uncoupler activity
|
GO:2000275 |
3 |
0.161
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.160
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.159
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.158
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.158
|
|
|
|
cell fate determination
|
GO:0001709 |
32 |
0.157
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.156
|
|
|
|
metanephros development
|
GO:0001656 |
79 |
0.155
|
|
|
|
intra s dna damage checkpoint
|
GO:0031573 |
4 |
0.154
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.152
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.151
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.151
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.148
|
|
|
|
neuroblast differentiation
|
GO:0014016 |
2 |
0.148
|
Worm |
|
|
brain morphogenesis
|
GO:0048854 |
32 |
0.147
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.146
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.145
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.145
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.145
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.145
|
|
|
|
positive regulation of mechanoreceptor differentiation
|
GO:0045633 |
1 |
0.144
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.144
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.142
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.142
|
|
|
|
negative regulation of astrocyte differentiation
|
GO:0048712 |
10 |
0.142
|
|
|
|
intestinal epithelial structure maintenance
|
GO:0060729 |
4 |
0.141
|
|
|
|
negative regulation of muscle cell differentiation
|
GO:0051148 |
33 |
0.140
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.140
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.139
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.139
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
43 |
0.138
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.138
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.138
|
|
|
|
negative regulation of peroxisome proliferator activated receptor signaling pathway
|
GO:0035359 |
3 |
0.138
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.136
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.135
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.134
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.134
|
Human |
|
|
cerebral cortex neuron differentiation
|
GO:0021895 |
19 |
0.134
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.132
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.132
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.131
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.131
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.130
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.129
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.127
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.125
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.124
|
|
|
|
v d j recombination
|
GO:0033151 |
14 |
0.120
|
|
|
|
dna templated transcription initiation
|
GO:0006352 |
13 |
0.119
|
Mouse |
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
10 |
0.118
|
|
|
|
negative regulation of b cell differentiation
|
GO:0045578 |
4 |
0.118
|
|
|
|
osteoclast proliferation
|
GO:0002158 |
4 |
0.118
|
|
|
|
negative regulation of chromatin silencing
|
GO:0031936 |
1 |
0.116
|
|
|
|
thymus development
|
GO:0048538 |
41 |
0.116
|
|
|
|
adipose tissue development
|
GO:0060612 |
25 |
0.116
|
|
|
|
spinal cord oligodendrocyte cell differentiation
|
GO:0021529 |
3 |
0.116
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.116
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.114
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.113
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.112
|
|
|
|
regulation of translational initiation by iron
|
GO:0006447 |
2 |
0.112
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.111
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.111
|
|
|
|
regulation of oligodendrocyte differentiation
|
GO:0048713 |
23 |
0.111
|
|
|
|
neuroblast fate commitment
|
GO:0014017 |
1 |
0.111
|
Worm |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.110
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.110
|
|
|
|
regulation of auditory receptor cell differentiation
|
GO:0045607 |
4 |
0.110
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.109
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.109
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
27 |
0.109
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.108
|
Human |
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.108
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.106
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.105
|
Worm |
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.105
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.104
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.104
|
|
|
|
negative regulation of chromatin modification
|
GO:1903309 |
19 |
0.103
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.103
|
|
|
|
collagen metabolic process
|
GO:0032963 |
17 |
0.103
|
|
|
|
positive regulation of glial cell differentiation
|
GO:0045687 |
21 |
0.103
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.103
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
41 |
0.103
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.102
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.102
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.101
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.101
|
Human |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.100
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.100
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.099
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
27 |
0.099
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.099
|
|
|
|
pancreatic a cell fate commitment
|
GO:0003326 |
2 |
0.099
|
|
|
|
endocardial cushion to mesenchymal transition involved in heart valve formation
|
GO:0003199 |
4 |
0.099
|
|
|
|
spinal cord oligodendrocyte cell fate specification
|
GO:0021530 |
3 |
0.098
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.098
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.097
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.097
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.096
|
Human |
|
|
cellular response to metal ion
|
GO:0071248 |
31 |
0.095
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.095
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.095
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
25 |
0.095
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.093
|
|
|
|
embryonic digestive tract development
|
GO:0048566 |
27 |
0.093
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.092
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.092
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.092
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.091
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.091
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.091
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
3 |
0.090
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.090
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.090
|
|
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
17 |
0.089
|
|
|
|
outflow tract morphogenesis
|
GO:0003151 |
53 |
0.088
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.087
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
28 |
0.086
|
Mouse |
|
|
enucleate erythrocyte differentiation
|
GO:0043353 |
8 |
0.086
|
|
|
|
cell proliferation involved in heart valve development
|
GO:2000793 |
2 |
0.086
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.083
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.083
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.083
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
33 |
0.082
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.082
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.082
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.081
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.081
|
|
|
|
endodermal digestive tract morphogenesis
|
GO:0061031 |
4 |
0.081
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.080
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.079
|
|
|
|
notochord development
|
GO:0030903 |
20 |
0.079
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.079
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.078
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.078
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.077
|
|
|
|
negative regulation of oligodendrocyte differentiation
|
GO:0048715 |
11 |
0.077
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.077
|
|
|
|
negative regulation of histone modification
|
GO:0031057 |
18 |
0.077
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.076
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.076
|
|
|
|
deltoid tuberosity development
|
GO:0035993 |
3 |
0.076
|
|
|
|
locomotion involved in locomotory behavior
|
GO:0031987 |
8 |
0.075
|
|
|
|
negative regulation of cell aging
|
GO:0090344 |
5 |
0.075
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.075
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.075
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.075
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.075
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.075
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.074
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.074
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.073
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.072
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.072
|
|
|
|
aortic valve morphogenesis
|
GO:0003180 |
4 |
0.072
|
|
|
|
regulation of mast cell differentiation
|
GO:0060375 |
3 |
0.072
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.072
|
|
|
|
neural retina development
|
GO:0003407 |
41 |
0.072
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
30 |
0.071
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.070
|
|
|
|
regulation of astrocyte differentiation
|
GO:0048710 |
20 |
0.070
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.070
|
|
|
|
positive regulation of mitotic sister chromatid separation
|
GO:1901970 |
2 |
0.069
|
|
|
|
cell proliferation involved in outflow tract morphogenesis
|
GO:0061325 |
4 |
0.068
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.068
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.067
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.067
|
|
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.067
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.067
|
|
|
|
pancreatic pp cell fate commitment
|
GO:0003329 |
2 |
0.066
|
|
|
|
central nervous system myelination
|
GO:0022010 |
12 |
0.066
|
|
|
|
semaphorin plexin signaling pathway involved in outflow tract morphogenesis
|
GO:0071527 |
1 |
0.066
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.066
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.065
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.064
|
Fly |
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.064
|
|
|
|
positive regulation of chronic inflammatory response
|
GO:0002678 |
4 |
0.064
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
68 |
0.064
|
|
|
|
spinal cord development
|
GO:0021510 |
81 |
0.064
|
|
|
|
embryonic heart tube formation
|
GO:0003144 |
1 |
0.062
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.062
|
|
|
|
regulation of macrophage differentiation
|
GO:0045649 |
9 |
0.062
|
|
|
|
glial cell fate specification
|
GO:0021780 |
5 |
0.061
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.061
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.061
|
|
|
|
positive regulation of nuclear division
|
GO:0051785 |
27 |
0.061
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.060
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.060
|
|
|
|
regulation of translational initiation
|
GO:0006446 |
15 |
0.060
|
|
|
|
mammary gland epithelial cell differentiation
|
GO:0060644 |
13 |
0.059
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
67 |
0.059
|
|
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.059
|
|
|
|
establishment of monopolar cell polarity
|
GO:0061162 |
8 |
0.059
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.059
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process
|
GO:2000763 |
1 |
0.059
|
|
|
|
chromatin silencing
|
GO:0006342 |
15 |
0.059
|
|
|
|
positive regulation of synaptic plasticity
|
GO:0031915 |
4 |
0.059
|
|
|
|
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation
|
GO:2000802 |
1 |
0.059
|
|
|
|
negative regulation of glial cell differentiation
|
GO:0045686 |
21 |
0.059
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.058
|
Worm |
|
|
monocarboxylic acid transport
|
GO:0015718 |
44 |
0.058
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.058
|
|
|
|
positive regulation of mitosis
|
GO:0045840 |
14 |
0.058
|
|
|
|
negative regulation of fat cell differentiation
|
GO:0045599 |
36 |
0.057
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.057
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.057
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.057
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.057
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
18 |
0.057
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.057
|
Fly |
|
|
organic anion transport
|
GO:0015711 |
137 |
0.057
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.057
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.056
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.056
|
|
|
|
positive regulation of translation
|
GO:0045727 |
19 |
0.056
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
29 |
0.056
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.055
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.054
|
|
|
|
cerebellar granule cell precursor tangential migration
|
GO:0021935 |
1 |
0.054
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.054
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.054
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.054
|
|
|
|
neuroblast fate determination
|
GO:0007400 |
1 |
0.054
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.053
|
|
|
|
hemangioblast cell differentiation
|
GO:0060217 |
1 |
0.053
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.053
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.053
|
Fly |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.053
|
|
|
|
megakaryocyte differentiation
|
GO:0030219 |
26 |
0.053
|
|
|
|
cardiac septum development
|
GO:0003279 |
59 |
0.052
|
|
|
|
head morphogenesis
|
GO:0060323 |
34 |
0.052
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.052
|
|
|
|
sclerotome development
|
GO:0061056 |
4 |
0.052
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.052
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.051
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.051
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.051
|
|
|
|
regulation of corticotropin releasing hormone secretion
|
GO:0043397 |
2 |
0.051
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.051
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
34 |
0.051
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.051
|
|
|
|
response to antibiotic
|
GO:0046677 |
11 |
0.051
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.051
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.050
|
Human |
|
|
female meiosis chromosome segregation
|
GO:0016321 |
1 |
0.050
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
3 |
0.049
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
3 |
0.049
|
|
|
|
meiosis i
|
GO:0007127 |
60 |
0.049
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.049
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.049
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.049
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.048
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.048
|
|
|
|
rna splicing via transesterification reactions
|
GO:0000375 |
43 |
0.048
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.048
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.047
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.047
|
|
|
|
negative regulation of oxidative phosphorylation uncoupler activity
|
GO:2000276 |
2 |
0.047
|
|
|
|
pons development
|
GO:0021548 |
13 |
0.047
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.047
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.046
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.046
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.046
|
|
|
|
corpus callosum development
|
GO:0022038 |
10 |
0.046
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.046
|
|
|
|
positive regulation of ubiquitin protein transferase activity
|
GO:0051443 |
4 |
0.045
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.045
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.045
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.045
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.045
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.045
|
|
|
|
aggressive behavior
|
GO:0002118 |
7 |
0.045
|
|
|
|
gonad morphogenesis
|
GO:0035262 |
1 |
0.045
|
Worm |
|
|
mrna processing
|
GO:0006397 |
63 |
0.045
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.044
|
|