Mus musculus

133 known processes

Tcf7

transcription factor 7, T-cell specific

(Aliases: TCF-1,AI465550,Tcf1)

Tcf7 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
secretory granule localization GO:0032252 3 0.993
Mouse
insulin metabolic process GO:1901142 3 0.963
Mouse
somatic diversification of t cell receptor genes GO:0002568 5 0.937
formation of radial glial scaffolds GO:0021943 4 0.936
Mouse
retinoic acid metabolic process GO:0042573 12 0.873
terpenoid biosynthetic process GO:0016114 7 0.868
regulation of transcription during mitosis GO:0045896 1 0.863
Mouse
retinoic acid biosynthetic process GO:0002138 7 0.848
diterpenoid biosynthetic process GO:0016102 7 0.814
regulation of transcription from rna polymerase ii promoter mitotic GO:0046021 1 0.811
Mouse
defecation GO:0030421 1 0.806
Worm
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter GO:0072364 7 0.798
Mouse
positive regulation of transcription during mitosis GO:0045897 1 0.795
Mouse
triglyceride biosynthetic process GO:0019432 17 0.783
Mouse
t cell receptor v d j recombination GO:0033153 5 0.774
trachea gland development GO:0061153 3 0.771
Mouse
regulation of gluconeogenesis by regulation of transcription from rna polymerase ii promoter GO:0035947 7 0.765
Mouse
regulation of asymmetric cell division GO:0009786 4 0.736
Worm
leukocyte differentiation GO:0002521 342 0.719
regulation of excretion GO:0044062 5 0.702
Worm
somatic recombination of t cell receptor gene segments GO:0002681 5 0.694
positive regulation of triglyceride metabolic process GO:0090208 9 0.676
Mouse
terpenoid metabolic process GO:0006721 25 0.628
axial mesoderm morphogenesis GO:0048319 5 0.614
Mouse
transmission of nerve impulse GO:0019226 76 0.581
carbohydrate metabolic process GO:0005975 230 0.574
Mouse
regulation of hydrolase activity GO:0051336 246 0.565
regulation of triglyceride biosynthetic process GO:0010866 10 0.556
Mouse
adaptive immune response GO:0002250 155 0.555
Mouse
regulation of isoprenoid metabolic process GO:0019747 1 0.510
lymphocyte differentiation GO:0030098 242 0.492
hexose metabolic process GO:0019318 98 0.486
Mouse
energy derivation by oxidation of organic compounds GO:0015980 77 0.478
Mouse
acylglycerol biosynthetic process GO:0046463 18 0.460
Mouse
isoprenoid biosynthetic process GO:0008299 9 0.453
immune effector process GO:0002252 321 0.441
Mouse
generation of precursor metabolites and energy GO:0006091 103 0.440
Mouse
myeloid cell differentiation GO:0030099 233 0.439
diterpenoid metabolic process GO:0016101 24 0.435
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.429
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.427
cell adhesion GO:0007155 329 0.427
Mouse
lipid biosynthetic process GO:0008610 179 0.417
Mouse
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 4 0.416
regulation of secretion GO:0051046 274 0.413
Mouse Worm
regulation of carbohydrate biosynthetic process GO:0043255 40 0.402
Mouse
embryonic genitalia morphogenesis GO:0030538 4 0.401
small molecule biosynthetic process GO:0044283 132 0.398
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.395
Mouse
wnt signaling pathway GO:0016055 188 0.394
cellular lipid metabolic process GO:0044255 323 0.393
Mouse
canonical wnt signaling pathway GO:0060070 130 0.384
positive regulation of lipid metabolic process GO:0045834 40 0.379
Mouse
leukocyte activation involved in immune response GO:0002366 126 0.375
Mouse
forebrain radial glial cell differentiation GO:0021861 4 0.373
Mouse
pharynx development GO:0060465 1 0.372
Worm
peptidyl amino acid modification GO:0018193 336 0.370
epithelial tube morphogenesis GO:0060562 303 0.370
Mouse
positive regulation of triglyceride biosynthetic process GO:0010867 6 0.358
Mouse
negative regulation of interleukin 5 production GO:0032714 4 0.357
glycogen metabolic process GO:0005977 32 0.355
Mouse
polarity specification of proximal distal axis GO:0010085 2 0.355
Worm
regulation of homeostatic process GO:0032844 182 0.354
Mouse
retinoid metabolic process GO:0001523 24 0.354
muscle cell differentiation GO:0042692 261 0.351
Mouse
negative regulation of cell proliferation GO:0008285 296 0.350
multicellular organismal signaling GO:0035637 91 0.350
somatic diversification of immune receptors GO:0002200 53 0.341
cellular response to interleukin 4 GO:0071353 21 0.340
Human
hypothalamus cell differentiation GO:0021979 8 0.337
action potential GO:0001508 78 0.335
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.334
regulation of myeloid cell differentiation GO:0045637 96 0.331
apoptotic signaling pathway GO:0097190 306 0.331
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.325
Mouse
cell activation involved in immune response GO:0002263 126 0.322
Mouse
positive regulation of apoptotic process GO:0043065 217 0.320
Mouse
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.319
neuronal action potential GO:0019228 54 0.318
dna metabolic process GO:0006259 303 0.317
acylglycerol metabolic process GO:0006639 55 0.316
Mouse
granulocyte differentiation GO:0030851 17 0.314
regulation of neuron differentiation GO:0045664 281 0.312
regulation of carbohydrate metabolic process GO:0006109 75 0.311
Mouse
negative regulation of interleukin 13 production GO:0032696 2 0.307
oxidation reduction process GO:0055114 342 0.307
Mouse
cytokine production GO:0001816 319 0.304
regulation of peptidase activity GO:0052547 96 0.301
t cell differentiation GO:0030217 174 0.301
cell fate commitment GO:0045165 210 0.301
Mouse Worm
glycerolipid biosynthetic process GO:0045017 50 0.299
Mouse
posttranscriptional gene silencing GO:0016441 10 0.294
Worm
jnk cascade GO:0007254 72 0.290
positive regulation of programmed cell death GO:0043068 218 0.287
Mouse
regulation of endopeptidase activity GO:0052548 89 0.286
organic acid biosynthetic process GO:0016053 86 0.285
positive regulation of secretion by cell GO:1903532 114 0.284
Mouse
leukocyte proliferation GO:0070661 172 0.283
Mouse
cd4 positive alpha beta t cell activation GO:0035710 45 0.281
Mouse
rhythmic process GO:0048511 174 0.274
Worm
b cell activation GO:0042113 161 0.273
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 65 0.271
single organism cell adhesion GO:0098602 156 0.270
Mouse
sensory system development GO:0048880 3 0.270
stem cell development GO:0048864 219 0.269
Mouse
regulation of triglyceride metabolic process GO:0090207 17 0.268
Mouse
rna interference GO:0016246 2 0.267
Worm
regulation of cellular amino acid metabolic process GO:0006521 5 0.263
homeostasis of number of cells GO:0048872 210 0.262
stem cell maintenance GO:0019827 130 0.259
Mouse
skeletal system development GO:0001501 356 0.258
respiratory system development GO:0060541 190 0.258
Mouse Fly
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.257
alpha beta t cell differentiation GO:0046632 69 0.254
interspecies interaction between organisms GO:0044419 83 0.254
regulation of cytokine production GO:0001817 266 0.248
mapk cascade GO:0000165 281 0.248
regulation of system process GO:0044057 200 0.244
Worm
hormone metabolic process GO:0042445 86 0.240
regulation of mapk cascade GO:0043408 248 0.240
carboxylic acid biosynthetic process GO:0046394 86 0.240
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.239
Mouse
ossification GO:0001503 216 0.239
Mouse
insulin secretion GO:0030073 89 0.238
Mouse
t cell activation GO:0042110 289 0.232
forebrain development GO:0030900 302 0.232
Mouse
regulation of lipid biosynthetic process GO:0046890 54 0.231
Mouse
peptidyl lysine modification GO:0018205 77 0.231
regulation of lipid metabolic process GO:0019216 118 0.229
Mouse
viral gene expression GO:0019080 3 0.227
ras protein signal transduction GO:0007265 77 0.225
regulation of protein binding GO:0043393 60 0.222
lymphocyte activation involved in immune response GO:0002285 93 0.218
Mouse
digestive tract development GO:0048565 190 0.217
response to inorganic substance GO:0010035 96 0.216
hormone secretion GO:0046879 128 0.216
Mouse
urogenital system development GO:0001655 261 0.214
regulation of cell cycle GO:0051726 281 0.213
organelle localization GO:0051640 179 0.213
Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.211
positive regulation of hormone secretion GO:0046887 38 0.209
Mouse
regulation of membrane potential GO:0042391 192 0.203
negative regulation of cellular protein metabolic process GO:0032269 247 0.203
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.202
t helper 1 type immune response GO:0042088 25 0.199
Mouse
fat cell differentiation GO:0045444 160 0.197
Mouse
regulation of binding GO:0051098 111 0.195
regulation of cellular response to growth factor stimulus GO:0090287 82 0.194
Mouse
mesoderm development GO:0007498 100 0.194
Mouse Worm
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.193
Mouse
sensory organ morphogenesis GO:0090596 242 0.192
interleukin 4 production GO:0032633 24 0.192
positive regulation of cell death GO:0010942 224 0.192
Mouse
blood vessel morphogenesis GO:0048514 285 0.190
Mouse
gluconeogenesis GO:0006094 39 0.189
Mouse
posttranscriptional gene silencing by rna GO:0035194 10 0.189
Worm
protein processing GO:0016485 163 0.189
cellular amine metabolic process GO:0044106 44 0.189
regulation of neuron projection development GO:0010975 169 0.187
regulation of apoptotic signaling pathway GO:2001233 197 0.187
neutrophil differentiation GO:0030223 3 0.187
regulation of cellular ketone metabolic process GO:0010565 66 0.185
Mouse
regulation of cellular response to stress GO:0080135 159 0.185
carbohydrate biosynthetic process GO:0016051 74 0.184
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.183
organ regeneration GO:0031100 2 0.182
cellular response to hormone stimulus GO:0032870 150 0.181
energy reserve metabolic process GO:0006112 39 0.181
Mouse
regulation of proteolysis GO:0030162 164 0.179
muscle cell development GO:0055001 133 0.178
stress activated protein kinase signaling cascade GO:0031098 81 0.178
cellular response to lipid GO:0071396 145 0.178
positive regulation of protein phosphorylation GO:0001934 242 0.176
single organismal cell cell adhesion GO:0016337 131 0.176
Mouse
positive regulation of protein modification process GO:0031401 299 0.175
histone modification GO:0016570 159 0.174
small gtpase mediated signal transduction GO:0007264 97 0.174
isoprenoid metabolic process GO:0006720 29 0.173
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.173
development of primary sexual characteristics GO:0045137 143 0.170
Worm
negative regulation of protein phosphorylation GO:0001933 126 0.170
regulation of hormone levels GO:0010817 211 0.168
Mouse
vesicle localization GO:0051648 86 0.168
Mouse
positive regulation of cellular carbohydrate metabolic process GO:0010676 29 0.166
Mouse
regulation of jnk cascade GO:0046328 62 0.166
negative regulation of immune system process GO:0002683 209 0.166
regulation of secretion by cell GO:1903530 249 0.166
Mouse
trachea submucosa development GO:0061152 3 0.165
Mouse
regulation of cell motility GO:2000145 236 0.164
regulation of wnt signaling pathway GO:0030111 123 0.164
Mouse Fly
neural tube development GO:0021915 160 0.163
stem cell differentiation GO:0048863 268 0.163
Mouse
t helper 1 cell differentiation GO:0045063 13 0.161
Mouse
regulation of receptor binding GO:1900120 4 0.161
positive regulation of cell development GO:0010720 237 0.160
negative regulation of receptor binding GO:1900121 1 0.159
wound healing GO:0042060 157 0.159
monocarboxylic acid biosynthetic process GO:0072330 61 0.159
glucan metabolic process GO:0044042 32 0.159
Mouse
positive regulation of peptide secretion GO:0002793 33 0.158
Mouse
gliogenesis GO:0042063 141 0.158
Mouse
germ cell development GO:0007281 185 0.156
regulation of viral transcription GO:0046782 3 0.156
axial mesoderm development GO:0048318 8 0.155
Mouse
t cell differentiation in thymus GO:0033077 77 0.155
striated muscle tissue development GO:0014706 293 0.155
Mouse
protein maturation GO:0051604 176 0.155
cellular amino acid metabolic process GO:0006520 103 0.153
negative regulation of phosphorus metabolic process GO:0010563 184 0.152
striated muscle cell development GO:0055002 125 0.152
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.151
Mouse
regulation of vitamin metabolic process GO:0030656 3 0.150
positive regulation of gluconeogenesis GO:0045722 11 0.149
Mouse
negative regulation of bmp signaling pathway GO:0030514 35 0.148
Mouse
regulation of protein kinase activity GO:0045859 232 0.148
dna recombination GO:0006310 92 0.148
positive regulation of cell adhesion GO:0045785 80 0.147
peptide transport GO:0015833 133 0.147
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.146
lateral line system development GO:0048925 1 0.145
regulation of cell cycle process GO:0010564 160 0.144
polysaccharide metabolic process GO:0005976 39 0.143
Mouse
regulation of canonical wnt signaling pathway GO:0060828 82 0.143
angiogenesis GO:0001525 201 0.143
Mouse
gene silencing GO:0016458 38 0.143
Worm
axonogenesis GO:0007409 274 0.143
viral life cycle GO:0019058 36 0.142
myeloid cell homeostasis GO:0002262 114 0.142
regulation of cell migration GO:0030334 219 0.142
gland development GO:0048732 330 0.140
Mouse Fly
vitamin metabolic process GO:0006766 23 0.140
limbic system development GO:0021761 72 0.139
Mouse
somatic stem cell maintenance GO:0035019 47 0.139
Mouse
regulation of osteoblast differentiation GO:0045667 67 0.137
embryonic placenta development GO:0001892 98 0.137
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.137
Human
cellular response to extracellular stimulus GO:0031668 81 0.133
Mouse
glial cell differentiation GO:0010001 131 0.133
Mouse
negative regulation of cytokine production GO:0001818 84 0.132
chromatin modification GO:0016568 187 0.132
b cell proliferation GO:0042100 53 0.131
Mouse
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.130
Mouse
regulation of stress activated mapk cascade GO:0032872 69 0.130
amide transport GO:0042886 138 0.130
Mouse
labyrinthine layer development GO:0060711 49 0.130
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.130
Mouse
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.128
apoptotic process in bone marrow GO:0071839 1 0.128
response to fibroblast growth factor GO:0071774 47 0.128
Mouse
v d j recombination GO:0033151 14 0.128
peptide hormone secretion GO:0030072 109 0.128
Mouse
immune response regulating signaling pathway GO:0002764 125 0.128
digestive system development GO:0055123 200 0.127
negative regulation of phosphate metabolic process GO:0045936 184 0.126
regulation of fat cell differentiation GO:0045598 81 0.124
Mouse
cellular ketone metabolic process GO:0042180 84 0.124
Mouse
camera type eye development GO:0043010 266 0.124
cell division GO:0051301 120 0.124
Mouse Worm
cellular chemical homeostasis GO:0055082 215 0.123
Mouse
embryonic epithelial tube formation GO:0001838 130 0.123
cellular homeostasis GO:0019725 240 0.123
Mouse
alpha beta t cell activation involved in immune response GO:0002287 31 0.123
Mouse
neuron projection guidance GO:0097485 141 0.122
response to growth factor GO:0070848 198 0.121
Mouse
monosaccharide biosynthetic process GO:0046364 44 0.121
Mouse
lymphocyte mediated immunity GO:0002449 139 0.121
chemotaxis GO:0006935 247 0.119
stress activated mapk cascade GO:0051403 80 0.119
regulation of cell adhesion GO:0030155 154 0.118
Mouse
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.118
positive regulation of apoptotic signaling pathway GO:2001235 95 0.117
negative regulation of phosphorylation GO:0042326 166 0.116
cellular polysaccharide metabolic process GO:0044264 38 0.116
Mouse
regulation of cell division GO:0051302 76 0.115
Worm
histone h3 acetylation GO:0043966 14 0.115
positive regulation of hydrolase activity GO:0051345 148 0.114
mitotic cell cycle process GO:1903047 159 0.113
Worm
inflammatory response GO:0006954 244 0.112
regulation of muscle tissue development GO:1901861 97 0.112
Mouse
glucose homeostasis GO:0042593 128 0.111
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.111
regulation of interleukin 4 production GO:0032673 18 0.111
chromatin organization GO:0006325 206 0.111
positive regulation of leukocyte differentiation GO:1902107 86 0.110
cell type specific apoptotic process GO:0097285 268 0.110
epithelial cell proliferation GO:0050673 174 0.110
Mouse
microtubule based process GO:0007017 236 0.109
Worm
intracellular protein transport GO:0006886 204 0.109
Mouse
viral process GO:0016032 41 0.109
regulation of cellular amine metabolic process GO:0033238 20 0.109
regulation of protein processing GO:0070613 96 0.108
skeletal system morphogenesis GO:0048705 203 0.107
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.105
Mouse
lymphocyte proliferation GO:0046651 164 0.105
Mouse
cell growth GO:0016049 130 0.104
gonad development GO:0008406 141 0.104
Worm
regulation of hormone metabolic process GO:0032350 15 0.104
regulation of myeloid leukocyte differentiation GO:0002761 58 0.103
protein modification by small protein conjugation GO:0032446 187 0.103
negative regulation of hydrolase activity GO:0051346 71 0.103
response to steroid hormone GO:0048545 56 0.102
intrinsic apoptotic signaling pathway GO:0097193 132 0.102
regulation of protein maturation GO:1903317 96 0.102
renal system development GO:0072001 225 0.102
brown fat cell differentiation GO:0050873 36 0.101
positive regulation of cell migration GO:0030335 109 0.101
modification by host of symbiont morphology or physiology GO:0051851 12 0.101
blastocyst development GO:0001824 80 0.101
myelination GO:0042552 74 0.101
Mouse
regulation of chromosome organization GO:0033044 83 0.100
positive regulation of nervous system development GO:0051962 221 0.100
bone mineralization GO:0030282 54 0.099
Mouse
salivary gland morphogenesis GO:0007435 33 0.099
Fly
negative regulation of apoptotic signaling pathway GO:2001234 104 0.098
multicellular organismal homeostasis GO:0048871 164 0.098
negative regulation of wnt signaling pathway GO:0030178 73 0.097
neuron migration GO:0001764 122 0.097
hormone mediated signaling pathway GO:0009755 23 0.096
regulation of organ growth GO:0046620 61 0.096
Mouse
telencephalon development GO:0021537 186 0.095
Mouse
response to organic cyclic compound GO:0014070 198 0.095
negative regulation of protein modification process GO:0031400 163 0.094
axon guidance GO:0007411 141 0.094
negative regulation of osteoblast differentiation GO:0045668 30 0.094
gastrulation GO:0007369 116 0.094
Mouse Worm
cell migration in hindbrain GO:0021535 16 0.093
Mouse
positive regulation of cell cycle GO:0045787 92 0.093
metal ion homeostasis GO:0055065 189 0.093
muscle fiber development GO:0048747 76 0.093
protein ubiquitination GO:0016567 171 0.092
negative regulation of molecular function GO:0044092 258 0.091
protein kinase b signaling GO:0043491 74 0.091
kidney development GO:0001822 213 0.090
internal protein amino acid acetylation GO:0006475 42 0.090
cytoplasmic transport GO:0016482 234 0.089
Mouse
posttranscriptional regulation of gene expression GO:0010608 155 0.088
Worm
positive regulation of lymphocyte activation GO:0051251 140 0.088
regulation of lymphocyte activation GO:0051249 240 0.087
segmentation GO:0035282 93 0.087
Mouse
regulation of peptide transport GO:0090087 91 0.087
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.087
negative regulation of endopeptidase activity GO:0010951 44 0.086
negative regulation of ossification GO:0030279 49 0.086
regulation of cell projection organization GO:0031344 206 0.086
response to molecule of bacterial origin GO:0002237 143 0.085
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.085
regulation of myelination GO:0031641 20 0.085
Mouse
cellular response to carbohydrate stimulus GO:0071322 50 0.085
Mouse
negative regulation of cell development GO:0010721 169 0.084
cellular response to external stimulus GO:0071496 88 0.084
Mouse
alpha beta t cell activation GO:0046631 91 0.083
rho protein signal transduction GO:0007266 32 0.083
protein localization to nucleus GO:0034504 121 0.083
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.083
actin cytoskeleton organization GO:0030036 220 0.083
negative regulation of peptidase activity GO:0010466 46 0.083
spermatogenesis GO:0007283 284 0.083
regulation of cellular catabolic process GO:0031329 242 0.083
ensheathment of neurons GO:0007272 76 0.082
Mouse
embryonic digestive tract development GO:0048566 27 0.081
response to organonitrogen compound GO:0010243 246 0.081
hypothalamus development GO:0021854 16 0.081
palate development GO:0060021 76 0.081
Mouse
cilium morphogenesis GO:0060271 102 0.081
carbohydrate homeostasis GO:0033500 128 0.081
Mouse
myoblast differentiation GO:0045445 52 0.079
Mouse
neuroblast differentiation GO:0014016 2 0.079
regulation of establishment of protein localization GO:0070201 181 0.079
positive regulation of cell motility GO:2000147 116 0.079
viral transcription GO:0019083 3 0.078
negative regulation of cellular amine metabolic process GO:0033239 1 0.078
regulation of cytoplasmic transport GO:1903649 112 0.078
genitalia morphogenesis GO:0035112 11 0.078
covalent chromatin modification GO:0016569 163 0.077
t cell activation involved in immune response GO:0002286 43 0.076
Mouse
protein localization to organelle GO:0033365 185 0.076
Mouse
oligodendrocyte development GO:0014003 20 0.076
Mouse
positive regulation of proteolysis GO:0045862 85 0.075
response to transforming growth factor beta GO:0071559 88 0.075
regulation of anatomical structure size GO:0090066 178 0.075
axon ensheathment GO:0008366 76 0.075
Mouse
response to nutrient levels GO:0031667 109 0.073
Mouse
ear morphogenesis GO:0042471 118 0.073
leukocyte mediated immunity GO:0002443 174 0.072
protein targeting GO:0006605 143 0.072
Mouse
regulation of protein transport GO:0051223 163 0.072
myeloid leukocyte differentiation GO:0002573 119 0.072
placenta development GO:0001890 140 0.072
Mouse
negative regulation of nervous system development GO:0051961 156 0.072
negative regulation of growth GO:0045926 99 0.071
Mouse
positive regulation of stem cell differentiation GO:2000738 23 0.071
regulation of metal ion transport GO:0010959 106 0.071
dendrite development GO:0016358 115 0.071
muscle tissue development GO:0060537 308 0.071
Mouse
peptide secretion GO:0002790 114 0.070
Mouse
regulation of cell growth GO:0001558 91 0.070
antigen receptor mediated signaling pathway GO:0050851 64 0.069
regulation of transferase activity GO:0051338 263 0.069
muscle contraction GO:0006936 101 0.069
regulation of ras protein signal transduction GO:0046578 114 0.069
oogenesis GO:0048477 56 0.069
negative regulation of cell adhesion GO:0007162 45 0.068
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.068
Mouse
diencephalon development GO:0021536 63 0.068
Mouse
negative regulation of proteolysis GO:0045861 74 0.068
negative regulation of synapse assembly GO:0051964 3 0.067
embryonic organ morphogenesis GO:0048562 276 0.067
establishment of planar polarity GO:0001736 28 0.067
response to extracellular stimulus GO:0009991 127 0.067
Mouse
female gamete generation GO:0007292 74 0.067
positive regulation of growth GO:0045927 104 0.067
skin development GO:0043588 220 0.067
Mouse
catenin import into nucleus GO:0035411 6 0.067
Mouse
response to metal ion GO:0010038 47 0.067
negative regulation of cell motility GO:2000146 61 0.067
positive regulation of cellular amine metabolic process GO:0033240 5 0.066
developmental maturation GO:0021700 193 0.066
cellular response to organonitrogen compound GO:0071417 145 0.066
epithelial tube formation GO:0072175 130 0.066
response to starvation GO:0042594 65 0.066
Mouse
negative regulation of cell migration GO:0030336 59 0.066
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.066
negative regulation of protein processing GO:0010955 79 0.065
cellular response to acid chemical GO:0071229 68 0.065
multicellular organism growth GO:0035264 161 0.065
Mouse
morphogenesis of a polarized epithelium GO:0001738 37 0.065
regulation of organ morphogenesis GO:2000027 144 0.065
cell chemotaxis GO:0060326 81 0.065
t cell selection GO:0045058 34 0.064
regulation of cell proliferation involved in tissue homeostasis GO:0060784 1 0.064
limb morphogenesis GO:0035108 149 0.064
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.064
positive regulation of cell cycle process GO:0090068 61 0.064
renal tubule development GO:0061326 87 0.063
actin filament organization GO:0007015 113 0.063
regulation of nucleotide catabolic process GO:0030811 122 0.063
positive regulation of t cell activation GO:0050870 101 0.063
cellular metal ion homeostasis GO:0006875 151 0.063
regulation of cellular component size GO:0032535 121 0.062
negative regulation of cellular component organization GO:0051129 194 0.062
cellular response to steroid hormone stimulus GO:0071383 33 0.062
regulation of innate immune response GO:0045088 91 0.062
limb development GO:0060173 166 0.062
Mouse
modification of morphology or physiology of other organism GO:0035821 18 0.062
male gamete generation GO:0048232 285 0.062
histone acetylation GO:0016573 41 0.061
exocrine system development GO:0035272 45 0.061
Fly
stem cell proliferation GO:0072089 117 0.061
Mouse Fly
apoptotic process involved in patterning of blood vessels GO:1902262 6 0.060
Mouse
regionalization GO:0003002 337 0.060
Zebrafish Mouse Worm
negative regulation of protein maturation GO:1903318 79 0.060
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.059
Mouse
glycosyl compound metabolic process GO:1901657 246 0.059
regulation of peptide secretion GO:0002791 77 0.059
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.058
response to lipopolysaccharide GO:0032496 128 0.058
embryonic limb morphogenesis GO:0030326 126 0.058
Mouse
apoptotic process involved in development GO:1902742 28 0.058
Mouse
meiotic cell cycle GO:0051321 122 0.058
response to lithium ion GO:0010226 10 0.057
formation of primary germ layer GO:0001704 77 0.056
Mouse Worm
neural tube formation GO:0001841 108 0.056
hippocampus development GO:0021766 52 0.056
Mouse
positive regulation of nucleoside metabolic process GO:0045979 91 0.056
positive regulation of myeloid cell differentiation GO:0045639 43 0.056
neural precursor cell proliferation GO:0061351 121 0.056
Mouse
sprouting angiogenesis GO:0002040 26 0.056
Mouse
appendage morphogenesis GO:0035107 149 0.056
Mouse Fly
activation of immune response GO:0002253 138 0.056
mesenchymal cell development GO:0014031 93 0.055
Mouse
establishment of protein localization to organelle GO:0072594 118 0.055
Mouse
cell substrate adhesion GO:0031589 130 0.055
hair follicle development GO:0001942 85 0.055
methylation GO:0032259 134 0.055
positive regulation of gtp catabolic process GO:0033126 85 0.054
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.054
t cell differentiation involved in immune response GO:0002292 30 0.053
Mouse
sensory perception GO:0007600 245 0.053
Mouse
negative regulation of organ growth GO:0046621 17 0.053
Mouse
lung development GO:0030324 164 0.053
meiotic nuclear division GO:0007126 115 0.053
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.052
Mouse
positive regulation of gtpase activity GO:0043547 85 0.052
mesoderm formation GO:0001707 62 0.052
Mouse Worm
nucleocytoplasmic transport GO:0006913 139 0.052
Mouse
vagus nerve development GO:0021564 3 0.052
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.051
vagus nerve morphogenesis GO:0021644 2 0.051
protein acylation GO:0043543 64 0.051
oligodendrocyte differentiation GO:0048709 53 0.051
Mouse
positive regulation of cell growth GO:0030307 33 0.051
immunoglobulin mediated immune response GO:0016064 69 0.051
appendage development GO:0048736 166 0.050
Zebrafish Mouse Fly
immunoglobulin production GO:0002377 73 0.050
cartilage development GO:0051216 140 0.050
regulation of purine nucleotide metabolic process GO:1900542 169 0.050
digestive tract morphogenesis GO:0048546 147 0.050
organophosphate catabolic process GO:0046434 232 0.049

Tcf7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.068