Mus musculus

131 known processes

Tcf7l1

transcription factor 7-like 1 (T-cell specific, HMG box)

(Aliases: Tcf-3,bHLHb21,Tcf3)

Tcf7l1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
digestive tract development GO:0048565 190 0.881
Mouse Worm
digestive tract morphogenesis GO:0048546 147 0.873
Mouse Worm
urogenital system development GO:0001655 261 0.826
regionalization GO:0003002 337 0.785
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.760
regulation of cell migration GO:0030334 219 0.747
negative regulation of immune system process GO:0002683 209 0.734
canonical wnt signaling pathway GO:0060070 130 0.720
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.717
Zebrafish Mouse Fly
neural tube development GO:0021915 160 0.709
Zebrafish Mouse
gastrulation GO:0007369 116 0.709
Mouse Worm
cellular ketone metabolic process GO:0042180 84 0.688
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.673
kidney development GO:0001822 213 0.673
stem cell maintenance GO:0019827 130 0.668
leukocyte differentiation GO:0002521 342 0.667
Mouse
ossification GO:0001503 216 0.667
Mouse
stem cell proliferation GO:0072089 117 0.661
Mouse Fly
cartilage development GO:0051216 140 0.660
negative regulation of cell proliferation GO:0008285 296 0.651
mapk cascade GO:0000165 281 0.640
mesenchyme development GO:0060485 152 0.626
Mouse
muscle cell differentiation GO:0042692 261 0.624
Mouse
wnt signaling pathway GO:0016055 188 0.612
Zebrafish Mouse Fly
negative regulation of phosphorus metabolic process GO:0010563 184 0.611
epithelial tube formation GO:0072175 130 0.590
digestive system development GO:0055123 200 0.572
Mouse Worm
regulation of cellular ketone metabolic process GO:0010565 66 0.563
Mouse
skin development GO:0043588 220 0.561
cell fate commitment GO:0045165 210 0.550
Mouse Worm
negative regulation of protein metabolic process GO:0051248 282 0.549
cell adhesion GO:0007155 329 0.548
Mouse
lymphocyte differentiation GO:0030098 242 0.528
Mouse
ameboidal type cell migration GO:0001667 128 0.527
regulation of cell adhesion GO:0030155 154 0.524
Mouse
dephosphorylation GO:0016311 129 0.512
mesoderm development GO:0007498 100 0.508
single organismal cell cell adhesion GO:0016337 131 0.506
Mouse
erythrocyte differentiation GO:0030218 88 0.501
regulation of muscle tissue development GO:1901861 97 0.487
Mouse
epithelial tube morphogenesis GO:0060562 303 0.482
Mouse
negative regulation of molecular function GO:0044092 258 0.477
negative regulation of epithelial cell proliferation GO:0050680 64 0.474
cytoplasmic transport GO:0016482 234 0.473
Mouse
glial cell differentiation GO:0010001 131 0.465
Mouse
placenta development GO:0001890 140 0.451
Mouse
regulation of transferase activity GO:0051338 263 0.447
regulation of cell cycle process GO:0010564 160 0.443
primary neural tube formation GO:0014020 95 0.443
neural tube closure GO:0001843 90 0.439
neural tube formation GO:0001841 108 0.435
cardiac ventricle development GO:0003231 83 0.432
connective tissue development GO:0061448 179 0.425
regulation of kinase activity GO:0043549 249 0.424
blood vessel morphogenesis GO:0048514 285 0.422
Mouse
morphogenesis of a branching structure GO:0001763 203 0.420
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.415
regulation of protein targeting GO:1903533 61 0.414
regulation of mapk cascade GO:0043408 248 0.412
amine metabolic process GO:0009308 45 0.411
morphogenesis of embryonic epithelium GO:0016331 159 0.408
regulation of stem cell proliferation GO:0072091 78 0.406
Fly
positive regulation of nervous system development GO:0051962 221 0.403
spermatogenesis GO:0007283 284 0.402
limb development GO:0060173 166 0.402
Mouse
regulation of stem cell differentiation GO:2000736 50 0.399
response to growth factor GO:0070848 198 0.399
Mouse
regulation of cytoplasmic transport GO:1903649 112 0.385
tube formation GO:0035148 140 0.385
lung development GO:0030324 164 0.382
chemotaxis GO:0006935 247 0.380
embryonic organ morphogenesis GO:0048562 276 0.380
Zebrafish Mouse
fat cell differentiation GO:0045444 160 0.378
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.378
renal system development GO:0072001 225 0.376
skeletal system development GO:0001501 356 0.372
regulation of fat cell differentiation GO:0045598 81 0.372
Mouse
respiratory system development GO:0060541 190 0.371
Mouse Fly
cell fate determination GO:0001709 32 0.362
Worm
bmp signaling pathway GO:0030509 93 0.360
Mouse
cardiac chamber development GO:0003205 108 0.358
cell division GO:0051301 120 0.358
Mouse Worm
cerebellum development GO:0021549 77 0.345
regulation of cellular amino acid metabolic process GO:0006521 5 0.345
positive regulation of cellular amine metabolic process GO:0033240 5 0.338
skeletal system morphogenesis GO:0048705 203 0.336
regulation of mitotic cell cycle GO:0007346 126 0.336
hindbrain development GO:0030902 128 0.334
Zebrafish Mouse
positive regulation of cell motility GO:2000147 116 0.325
regulation of protein transport GO:0051223 163 0.324
gliogenesis GO:0042063 141 0.321
Mouse
regulation of establishment of protein localization GO:0070201 181 0.316
striated muscle tissue development GO:0014706 293 0.316
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.312
cell chemotaxis GO:0060326 81 0.309
ureteric bud development GO:0001657 94 0.308
positive regulation of protein kinase activity GO:0045860 144 0.305
regulation of organ morphogenesis GO:2000027 144 0.305
peptidyl tyrosine phosphorylation GO:0018108 143 0.304
epithelial cell morphogenesis GO:0003382 41 0.301
positive regulation of cell migration GO:0030335 109 0.300
astrocyte differentiation GO:0048708 43 0.299
metencephalon development GO:0022037 89 0.298
t cell differentiation in thymus GO:0033077 77 0.294
morphogenesis of a branching epithelium GO:0061138 193 0.292
Mouse
positive regulation of programmed cell death GO:0043068 218 0.292
Mouse
retina development in camera type eye GO:0060041 119 0.292
mitotic cell cycle GO:0000278 195 0.288
Worm
sensory organ morphogenesis GO:0090596 242 0.285
Zebrafish
cardiac septum development GO:0003279 59 0.283
camera type eye development GO:0043010 266 0.282
Zebrafish
epidermis development GO:0008544 187 0.279
branching morphogenesis of an epithelial tube GO:0048754 159 0.277
Mouse
peptidyl tyrosine modification GO:0018212 145 0.276
cardiac right atrium morphogenesis GO:0003213 3 0.274
positive regulation of protein modification process GO:0031401 299 0.272
positive regulation of cell death GO:0010942 224 0.272
Mouse
myeloid cell differentiation GO:0030099 233 0.271
positive regulation of protein phosphorylation GO:0001934 242 0.270
regulation of intracellular transport GO:0032386 159 0.270
germ cell development GO:0007281 185 0.264
appendage morphogenesis GO:0035107 149 0.264
Mouse Fly
forebrain development GO:0030900 302 0.263
Zebrafish Mouse
regulation of epithelial to mesenchymal transition GO:0010717 22 0.260
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.260
regulation of protein localization GO:0032880 231 0.258
wound healing GO:0042060 157 0.258
pallium development GO:0021543 120 0.258
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.257
gland development GO:0048732 330 0.250
Mouse Fly
neural precursor cell proliferation GO:0061351 121 0.248
Zebrafish Mouse
skeletal muscle organ development GO:0060538 163 0.242
Mouse
cellular amine metabolic process GO:0044106 44 0.241
regulation of nucleocytoplasmic transport GO:0046822 73 0.240
embryonic epithelial tube formation GO:0001838 130 0.240
regulation of neuron differentiation GO:0045664 281 0.239
muscle tissue development GO:0060537 308 0.238
Mouse
epithelial cell development GO:0002064 159 0.235
ear development GO:0043583 200 0.233
cerebral cortex development GO:0021987 86 0.233
respiratory tube development GO:0030323 167 0.232
organ growth GO:0035265 117 0.231
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.231
Mouse
cardiocyte differentiation GO:0035051 87 0.230
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.227
Mouse
molting cycle GO:0042303 90 0.225
muscle cell development GO:0055001 133 0.225
protein ubiquitination GO:0016567 171 0.223
positive regulation of cell development GO:0010720 237 0.223
retinal blood vessel morphogenesis GO:0061304 3 0.220
glucose homeostasis GO:0042593 128 0.215
Mouse
positive regulation of intracellular transport GO:0032388 70 0.215
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.214
cellular response to growth factor stimulus GO:0071363 197 0.213
Mouse
mesenchymal cell proliferation GO:0010463 44 0.213
epithelial to mesenchymal transition GO:0001837 47 0.212
Mouse
axis elongation involved in somitogenesis GO:0090245 4 0.212
appendage development GO:0048736 166 0.211
Mouse Fly
protein catabolic process GO:0030163 221 0.211
response to oxygen levels GO:0070482 62 0.210
photoreceptor cell differentiation GO:0046530 52 0.209
regulation of intracellular protein transport GO:0033157 82 0.207
regulation of cell motility GO:2000145 236 0.207
epithelial cell proliferation GO:0050673 174 0.206
Mouse
formation of primary germ layer GO:0001704 77 0.206
Mouse Worm
negative regulation of cell cycle GO:0045786 123 0.204
establishment of protein localization to organelle GO:0072594 118 0.203
Mouse
regulation of ossification GO:0030278 112 0.200
mitotic cell cycle process GO:1903047 159 0.199
Worm
positive regulation of mapk cascade GO:0043410 170 0.198
g1 s transition of mitotic cell cycle GO:0000082 57 0.197
angiogenesis GO:0001525 201 0.196
Mouse
limbic system development GO:0021761 72 0.194
Mouse
stem cell development GO:0048864 219 0.193
endothelium development GO:0003158 45 0.193
embryonic camera type eye development GO:0031076 36 0.193
Zebrafish
cellular response to lipid GO:0071396 145 0.191
neuron projection guidance GO:0097485 141 0.191
negative regulation of ossification GO:0030279 49 0.189
multicellular organism growth GO:0035264 161 0.189
Mouse
central nervous system neuron differentiation GO:0021953 162 0.186
negative regulation of fat cell differentiation GO:0045599 36 0.184
Mouse
intracellular protein transport GO:0006886 204 0.183
Mouse
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.183
tendon cell differentiation GO:0035990 4 0.182
cerebellum morphogenesis GO:0021587 42 0.182
negative regulation of phosphate metabolic process GO:0045936 184 0.181
b cell differentiation GO:0030183 78 0.181
cardiac muscle tissue development GO:0048738 130 0.181
carbohydrate homeostasis GO:0033500 128 0.180
Mouse
cellular amino acid metabolic process GO:0006520 103 0.179
regulation of osteoblast differentiation GO:0045667 67 0.177
negative regulation of protein modification process GO:0031400 163 0.175
mesenchymal cell differentiation GO:0048762 107 0.172
Mouse
cardiac septum morphogenesis GO:0060411 46 0.171
negative regulation of bmp signaling pathway GO:0030514 35 0.171
Mouse
endothelial cell differentiation GO:0045446 41 0.170
regulation of protein stability GO:0031647 52 0.169
t cell activation GO:0042110 289 0.169
Mouse
apoptotic signaling pathway GO:0097190 306 0.167
posttranscriptional regulation of gene expression GO:0010608 155 0.166
Worm
regulation of cellular amine metabolic process GO:0033238 20 0.165
regulation of bmp signaling pathway GO:0030510 60 0.164
Mouse
mesenchymal cell development GO:0014031 93 0.163
Mouse
cell cell junction organization GO:0045216 72 0.162
regulation of apoptotic signaling pathway GO:2001233 197 0.162
positive regulation of apoptotic process GO:0043065 217 0.161
Mouse
ribonucleotide metabolic process GO:0009259 291 0.161
positive regulation of cytoplasmic transport GO:1903651 40 0.160
regulation of protein kinase activity GO:0045859 232 0.159
axonogenesis GO:0007409 274 0.158
organelle fission GO:0048285 170 0.157
b cell activation GO:0042113 161 0.157
Mouse
protein import into nucleus GO:0006606 95 0.156
Mouse
transmission of nerve impulse GO:0019226 76 0.156
negative regulation of cellular component organization GO:0051129 194 0.156
bone morphogenesis GO:0060349 78 0.155
negative regulation of myoblast differentiation GO:0045662 18 0.155
peptidyl amino acid modification GO:0018193 336 0.153
heart morphogenesis GO:0003007 178 0.153
male gamete generation GO:0048232 285 0.152
negative regulation of phosphorylation GO:0042326 166 0.151
cell junction assembly GO:0034329 52 0.149
regulation of stem cell maintenance GO:2000036 17 0.149
mesonephros development GO:0001823 97 0.148
positive regulation of intracellular protein transport GO:0090316 42 0.148
lens morphogenesis in camera type eye GO:0002089 24 0.148
regulation of epithelial cell proliferation GO:0050678 141 0.147
Mouse
regulation of protein localization to nucleus GO:1900180 60 0.146
bone development GO:0060348 120 0.146
positive regulation of transferase activity GO:0051347 167 0.146
peptide transport GO:0015833 133 0.146
Mouse
asymmetric neuroblast division GO:0055059 1 0.145
kidney epithelium development GO:0072073 121 0.145
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.144
negative regulation of osteoblast differentiation GO:0045668 30 0.144
endochondral bone morphogenesis GO:0060350 50 0.143
embryonic heart tube morphogenesis GO:0003143 51 0.143
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.143
nuclear division GO:0000280 158 0.142
neuron migration GO:0001764 122 0.142
macromolecule catabolic process GO:0009057 281 0.141
oocyte axis specification GO:0007309 2 0.141
bone mineralization GO:0030282 54 0.141
Mouse
homeostasis of number of cells GO:0048872 210 0.141
mammary gland epithelium development GO:0061180 65 0.140
paraxial mesoderm development GO:0048339 18 0.140
Mouse
asymmetric stem cell division GO:0098722 3 0.139
nephron tubule morphogenesis GO:0072078 68 0.138
developmental growth involved in morphogenesis GO:0060560 138 0.137
glycosyl compound catabolic process GO:1901658 206 0.136
nephron tubule development GO:0072080 84 0.136
regulation of hormone levels GO:0010817 211 0.136
Mouse
telencephalon development GO:0021537 186 0.134
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.134
purine ribonucleotide metabolic process GO:0009150 290 0.133
determination of heart left right asymmetry GO:0061371 48 0.131
regulation of protein import into nucleus GO:0042306 52 0.130
muscle cell proliferation GO:0033002 52 0.129
response to organic cyclic compound GO:0014070 198 0.129
hair follicle development GO:0001942 85 0.128
formation of radial glial scaffolds GO:0021943 4 0.128
Mouse
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.128
nucleocytoplasmic transport GO:0006913 139 0.128
Mouse
establishment of planar polarity GO:0001736 28 0.127
developmental maturation GO:0021700 193 0.127
palate development GO:0060021 76 0.127
Mouse
skeletal muscle fiber development GO:0048741 58 0.125
regulation of cell cycle GO:0051726 281 0.124
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.124
sensory perception GO:0007600 245 0.123
Mouse
genitalia development GO:0048806 37 0.123
Mouse Worm
regulation of lymphocyte activation GO:0051249 240 0.122
muscle fiber development GO:0048747 76 0.121
regulation of canonical wnt signaling pathway GO:0060828 82 0.121
negative regulation of mitotic cell cycle GO:0045930 58 0.120
axon guidance GO:0007411 141 0.119
regulation of membrane potential GO:0042391 192 0.119
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.119
kidney morphogenesis GO:0060993 83 0.118
nitrogen compound transport GO:0071705 271 0.118
Mouse
embryonic heart tube development GO:0035050 65 0.118
somitogenesis GO:0001756 69 0.116
Mouse
hair cycle GO:0042633 90 0.115
positive regulation of protein transport GO:0051222 93 0.114
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.114
neuroblast proliferation GO:0007405 49 0.114
Mouse
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.114
cellular response to dna damage stimulus GO:0006974 207 0.114
cell cell signaling involved in cell fate commitment GO:0045168 35 0.113
defense response to gram negative bacterium GO:0050829 28 0.113
response to organonitrogen compound GO:0010243 246 0.113
cell junction organization GO:0034330 77 0.112
positive regulation of protein import into nucleus GO:0042307 26 0.111
regulation of protein serine threonine kinase activity GO:0071900 157 0.111
tissue migration GO:0090130 68 0.111
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.111
trachea cartilage morphogenesis GO:0060535 4 0.110
odontogenesis GO:0042476 78 0.110
Mouse
metanephros development GO:0001656 79 0.110
myotube differentiation GO:0014902 105 0.110
cellular homeostasis GO:0019725 240 0.109
Mouse
spinal cord development GO:0021510 81 0.108
keratinocyte proliferation GO:0043616 21 0.108
regulation of hippo signaling GO:0035330 1 0.108
epithelial cell migration GO:0010631 63 0.107
negative regulation of nervous system development GO:0051961 156 0.107
regulation of cellular catabolic process GO:0031329 242 0.106
regulation of cell division GO:0051302 76 0.106
Worm
limb morphogenesis GO:0035108 149 0.105
Mouse
protein localization to nucleus GO:0034504 121 0.105
Mouse
response to transforming growth factor beta GO:0071559 88 0.105
development of primary sexual characteristics GO:0045137 143 0.104
Worm
cell maturation GO:0048469 127 0.102
apoptotic process involved in morphogenesis GO:0060561 25 0.102
Mouse
ventricular septum development GO:0003281 42 0.102
formation of organ boundary GO:0010160 1 0.102
anatomical structure homeostasis GO:0060249 145 0.102
negative regulation of cell development GO:0010721 169 0.102
regulation of mitotic cell cycle phase transition GO:1901990 73 0.101
epithelium migration GO:0090132 63 0.101
nuclear import GO:0051170 95 0.101
Mouse
prostate gland epithelium morphogenesis GO:0060740 31 0.101
hormone secretion GO:0046879 128 0.101
Mouse
cell cell junction assembly GO:0007043 27 0.101
chondrocyte differentiation GO:0002062 72 0.101
regulation of establishment of planar polarity GO:0090175 28 0.100
regulation of embryonic development GO:0045995 71 0.100
modification dependent macromolecule catabolic process GO:0043632 133 0.100
purine ribonucleoside catabolic process GO:0046130 205 0.100
notch signaling pathway GO:0007219 71 0.099
actin cytoskeleton organization GO:0030036 220 0.099
hindlimb morphogenesis GO:0035137 42 0.099
convergent extension GO:0060026 14 0.099
cellular nitrogen compound catabolic process GO:0044270 280 0.099
hippocampus development GO:0021766 52 0.098
Mouse
regulation of mesenchymal cell proliferation GO:0010464 37 0.098
biomineral tissue development GO:0031214 64 0.098
Mouse
negative regulation of glial cell proliferation GO:0060253 4 0.098
tendon formation GO:0035992 4 0.098
prostate gland morphogenesis GO:0060512 32 0.097
cell fate specification GO:0001708 72 0.096
Worm
protein modification by small protein conjugation GO:0032446 187 0.096
adherens junction organization GO:0034332 28 0.096
negative regulation of gastrulation GO:2000542 3 0.095
jnk cascade GO:0007254 72 0.095
regulation of hormone secretion GO:0046883 88 0.094
Mouse
regulation of innate immune response GO:0045088 91 0.094
determination of left right symmetry GO:0007368 80 0.094
nephron morphogenesis GO:0072028 69 0.094
endocardial cell differentiation GO:0060956 4 0.094
axis elongation GO:0003401 30 0.094
lateral inhibition GO:0046331 1 0.093
ventricular septum morphogenesis GO:0060412 27 0.093
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.092
innate immune response GO:0045087 157 0.092
protein localization to organelle GO:0033365 185 0.092
Mouse
embryonic appendage morphogenesis GO:0035113 126 0.091
Mouse
regulation of homeostatic process GO:0032844 182 0.091
Mouse
regulation of epithelial cell migration GO:0010632 35 0.090
blastocyst development GO:0001824 80 0.090
non canonical wnt signaling pathway GO:0035567 33 0.090
developmental programmed cell death GO:0010623 41 0.089
Mouse
negative regulation of apoptotic signaling pathway GO:2001234 104 0.089
mitral valve development GO:0003174 4 0.089
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.089
regulation of gtp catabolic process GO:0033124 113 0.089
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.089
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.089
positive regulation of stem cell proliferation GO:2000648 59 0.088
myoblast differentiation GO:0045445 52 0.088
Mouse
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.088
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.088
cardiac endothelial cell differentiation GO:0003348 4 0.088
regulation of myotube differentiation GO:0010830 62 0.088
mesenchyme morphogenesis GO:0072132 32 0.088
Mouse
cell migration involved in gastrulation GO:0042074 13 0.087
dna metabolic process GO:0006259 303 0.087
Mouse
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.087
regulation of chondrocyte differentiation GO:0032330 33 0.087
mesoderm formation GO:0001707 62 0.086
Mouse Worm
regulation of gliogenesis GO:0014013 50 0.086
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.086
phospholipid metabolic process GO:0006644 87 0.085
stem cell differentiation GO:0048863 268 0.085
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.085
cellular protein catabolic process GO:0044257 155 0.084
negative regulation of intracellular signal transduction GO:1902532 167 0.084
morphogenesis of an epithelial sheet GO:0002011 27 0.083
single organism cell adhesion GO:0098602 156 0.083
Mouse
regulation of cell projection organization GO:0031344 206 0.083
cellular lipid metabolic process GO:0044255 323 0.083
Mouse
morphogenesis of a polarized epithelium GO:0001738 37 0.083
regulation of mitosis GO:0007088 29 0.082
nephron epithelium morphogenesis GO:0072088 68 0.082
multi multicellular organism process GO:0044706 109 0.082
embryonic skeletal system development GO:0048706 120 0.081
negative regulation of organelle organization GO:0010639 90 0.081
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.081
neuronal action potential GO:0019228 54 0.081
regulation of sphingolipid mediated signaling pathway GO:1902068 2 0.080
tube closure GO:0060606 91 0.080
metal ion homeostasis GO:0055065 189 0.080
regulation of striated muscle cell differentiation GO:0051153 81 0.080
positive regulation of cell cycle GO:0045787 92 0.080
mitotic nuclear division GO:0007067 48 0.079
renal vesicle induction GO:0072034 3 0.079
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.079
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.079
epithelial cell differentiation involved in kidney development GO:0035850 23 0.079
oocyte construction GO:0007308 2 0.079
regulation of system process GO:0044057 200 0.078
Worm
regulation of cellular response to stress GO:0080135 159 0.078
autonomic nervous system development GO:0048483 43 0.078
insulin secretion GO:0030073 89 0.077
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.077
locomotory behavior GO:0007626 195 0.077
somatic stem cell division GO:0048103 19 0.077
Mouse
cell type specific apoptotic process GO:0097285 268 0.077
regulation of response to wounding GO:1903034 189 0.076
stem cell division GO:0017145 30 0.076
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.076
glandular epithelial cell differentiation GO:0002067 38 0.075
single organism nuclear import GO:1902593 95 0.075
Mouse
negative regulation of kinase activity GO:0033673 81 0.075
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.074
gonad development GO:0008406 141 0.074
Worm
cardiac muscle cell differentiation GO:0055007 69 0.074
multicellular organismal homeostasis GO:0048871 164 0.073
regulation of cell cycle phase transition GO:1901987 77 0.073
oligodendrocyte development GO:0014003 20 0.073
Mouse
regulation of cartilage development GO:0061035 44 0.073
prostate gland development GO:0030850 48 0.072
positive regulation of striated muscle tissue development GO:0045844 31 0.072
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.072
Mouse
inner ear morphogenesis GO:0042472 101 0.072
cerebellar cortex development GO:0021695 48 0.072
regulation of hydrolase activity GO:0051336 246 0.071
negative regulation of prostatic bud formation GO:0060686 4 0.071
cation homeostasis GO:0055080 212 0.071
negative regulation of neuron differentiation GO:0045665 101 0.071
negative regulation of cellular amine metabolic process GO:0033239 1 0.071
renal tubule development GO:0061326 87 0.071
nucleotide metabolic process GO:0009117 332 0.071
positive regulation of response to wounding GO:1903036 66 0.071
mesoderm morphogenesis GO:0048332 64 0.070
regulation of proteolysis GO:0030162 164 0.070
embryonic limb morphogenesis GO:0030326 126 0.070
Mouse
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.069
renal tubule morphogenesis GO:0061333 72 0.069
protein modification by small protein conjugation or removal GO:0070647 207 0.069
defense response to bacterium GO:0042742 119 0.069
muscle tissue morphogenesis GO:0060415 53 0.069
striated muscle cell development GO:0055002 125 0.068
cytokine production GO:0001816 319 0.068
cell cell adhesion GO:0098609 41 0.067
regulation of secretion GO:0051046 274 0.067
Mouse Worm
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.067
organelle localization GO:0051640 179 0.067
Mouse
nephron development GO:0072006 109 0.067
negative regulation of defense response GO:0031348 77 0.067
oogenesis GO:0048477 56 0.067
blastocyst formation GO:0001825 33 0.066
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.066
metanephric mesenchyme morphogenesis GO:0072133 4 0.066
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.066
establishment or maintenance of cell polarity GO:0007163 86 0.065
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.065
nuclear transport GO:0051169 139 0.065
Mouse
stress activated mapk cascade GO:0051403 80 0.065
negative regulation of growth GO:0045926 99 0.065
Mouse
positive regulation of bmp signaling pathway GO:0030513 23 0.065
regulation of peptide hormone secretion GO:0090276 75 0.065
Mouse
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.065
regulation of cellular component biogenesis GO:0044087 181 0.064
small gtpase mediated signal transduction GO:0007264 97 0.064
mesonephric tubule development GO:0072164 94 0.064
purine ribonucleotide catabolic process GO:0009154 208 0.063
nucleoside triphosphate catabolic process GO:0009143 205 0.063
positive regulation of epithelial cell migration GO:0010634 19 0.063
deltoid tuberosity development GO:0035993 3 0.063
photoreceptor cell development GO:0042461 40 0.063
gastrulation with mouth forming second GO:0001702 29 0.063
neural crest cell differentiation GO:0014033 54 0.062
negative regulation of muscle cell differentiation GO:0051148 33 0.062
cell growth GO:0016049 130 0.062
central nervous system neuron development GO:0021954 67 0.062
heart valve development GO:0003170 23 0.061
purine containing compound metabolic process GO:0072521 311 0.061
heterocycle catabolic process GO:0046700 280 0.061
regulation of skeletal muscle fiber development GO:0048742 36 0.061
organic cyclic compound catabolic process GO:1901361 295 0.061
skeletal muscle cell differentiation GO:0035914 66 0.061
nucleobase containing small molecule metabolic process GO:0055086 352 0.061

Tcf7l1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.282
musculoskeletal system disease DOID:17 0 0.282
connective tissue disease DOID:65 0 0.282
bone disease DOID:0080001 0 0.105
disease of cellular proliferation DOID:14566 0 0.063