Mus musculus

231 known processes

Tek

endothelial-specific receptor tyrosine kinase

(Aliases: Tie2,Cd202b,Hyk,AA517024,tie-2)

Tek biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell adhesion GO:0007155 329 0.979
regulation of cell adhesion GO:0030155 154 0.931
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.924
Human
negative regulation of phosphorus metabolic process GO:0010563 184 0.870
cellular ketone metabolic process GO:0042180 84 0.818
positive regulation of cell migration GO:0030335 109 0.811
Human
negative regulation of phosphorylation GO:0042326 166 0.793
positive regulation of cell adhesion GO:0045785 80 0.774
t cell activation GO:0042110 289 0.766
wnt signaling pathway GO:0016055 188 0.749
regulation of cell migration GO:0030334 219 0.730
mapk cascade GO:0000165 281 0.702
Human
single organism cell adhesion GO:0098602 156 0.687
single organismal cell cell adhesion GO:0016337 131 0.614
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.612
negative regulation of cellular protein metabolic process GO:0032269 247 0.576
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.569
immune effector process GO:0002252 321 0.569
regulation of cellular amine metabolic process GO:0033238 20 0.555
cell migration involved in coronary angiogenesis GO:0060981 1 0.507
insulin like growth factor receptor signaling pathway GO:0048009 21 0.496
lamellipodium organization GO:0097581 29 0.488
regulation of wnt signaling pathway GO:0030111 123 0.488
regulation of cell motility GO:2000145 236 0.471
positive regulation of cell motility GO:2000147 116 0.443
Human
cellular response to organonitrogen compound GO:0071417 145 0.440
angiogenesis GO:0001525 201 0.436
ameboidal type cell migration GO:0001667 128 0.432
Human
peptidyl tyrosine modification GO:0018212 145 0.422
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.421
cellular response to insulin stimulus GO:0032869 78 0.421
insulin receptor signaling pathway GO:0008286 49 0.418
regulation of insulin receptor signaling pathway GO:0046626 21 0.408
cellular response to growth factor stimulus GO:0071363 197 0.403
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 1 0.402
negative regulation of wnt signaling pathway GO:0030178 73 0.391
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.388
response to growth factor GO:0070848 198 0.377
positive regulation of cellular amine metabolic process GO:0033240 5 0.375
heart trabecula formation GO:0060347 14 0.372
negative regulation of protein metabolic process GO:0051248 282 0.367
smooth muscle cell chemotaxis GO:0071670 2 0.365
cellular response to erythropoietin GO:0036018 1 0.362
blood vessel morphogenesis GO:0048514 285 0.362
negative regulation of phosphate metabolic process GO:0045936 184 0.355
posttranscriptional regulation of gene expression GO:0010608 155 0.336
cellular amine metabolic process GO:0044106 44 0.333
leukocyte proliferation GO:0070661 172 0.317
response to erythropoietin GO:0036017 1 0.310
blood circulation GO:0008015 195 0.308
regulation of angiogenesis GO:0045765 81 0.303
digestive tract morphogenesis GO:0048546 147 0.302
melanocyte migration GO:0097324 2 0.294
organelle assembly GO:0070925 177 0.294
response to peptide hormone GO:0043434 127 0.281
circulatory system process GO:0003013 197 0.278
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.276
cell substrate adhesion GO:0031589 130 0.269
cell cell junction organization GO:0045216 72 0.265
Human
regulation of system process GO:0044057 200 0.253
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.253
regulation of cellular ketone metabolic process GO:0010565 66 0.244
urogenital system development GO:0001655 261 0.238
cellular response to hormone stimulus GO:0032870 150 0.226
kidney development GO:0001822 213 0.223
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 16 0.223
regulation of vasculogenesis GO:2001212 9 0.223
inositol lipid mediated signaling GO:0048017 41 0.218
Human
embryonic organ morphogenesis GO:0048562 276 0.213
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.207
myeloid cell differentiation GO:0030099 233 0.206
metanephric glomerular mesangium development GO:0072223 3 0.205
heart morphogenesis GO:0003007 178 0.203
regulation of cell activation GO:0050865 289 0.203
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.201
sensory organ morphogenesis GO:0090596 242 0.201
erythropoietin mediated signaling pathway GO:0038162 1 0.201
endothelial cell apoptotic process GO:0072577 9 0.199
cell migration involved in vasculogenesis GO:0035441 2 0.198
regulation of cellular amino acid metabolic process GO:0006521 5 0.196
morphogenesis of a branching structure GO:0001763 203 0.194
vascular endothelial growth factor receptor signaling pathway GO:0048010 24 0.193
response to insulin GO:0032868 100 0.184
ion transmembrane transport GO:0034220 361 0.184
nephron development GO:0072006 109 0.183
cellular amino acid metabolic process GO:0006520 103 0.183
cellular response to thyroid hormone stimulus GO:0097067 1 0.176
germ cell development GO:0007281 185 0.174
dendritic cell cytokine production GO:0002371 3 0.171
cellular response to stem cell factor stimulus GO:0036216 3 0.168
regulation of mapk cascade GO:0043408 248 0.168
Human
renal system development GO:0072001 225 0.162
cardiac chamber development GO:0003205 108 0.162
regulation of blood vessel remodeling GO:0060312 3 0.159
relaxation of vascular smooth muscle GO:0060087 7 0.158
pigmentation GO:0043473 71 0.158
gastrulation GO:0007369 116 0.157
cardiac chamber morphogenesis GO:0003206 93 0.157
translation GO:0006412 93 0.156
regulation of translation GO:0006417 71 0.155
muscle tissue development GO:0060537 308 0.152
cytokine mediated signaling pathway GO:0019221 115 0.152
positive regulation of smooth muscle cell migration GO:0014911 4 0.150
amine metabolic process GO:0009308 45 0.148
canonical wnt signaling pathway GO:0060070 130 0.148
phosphatidylinositol mediated signaling GO:0048015 41 0.146
Human
kit signaling pathway GO:0038109 3 0.146
response to testosterone GO:0033574 3 0.145
response to organonitrogen compound GO:0010243 246 0.143
cellular response to peptide GO:1901653 92 0.143
neuron migration GO:0001764 122 0.140
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.140
cytokine production involved in immune response GO:0002367 34 0.140
regulation of epithelial cell proliferation GO:0050678 141 0.136
metanephric glomerulus vasculature morphogenesis GO:0072276 3 0.134
cardiac muscle fiber development GO:0048739 4 0.131
relaxation of smooth muscle GO:0044557 8 0.129
pro t cell differentiation GO:0002572 3 0.128
glomerulus development GO:0032835 40 0.127
cellular homeostasis GO:0019725 240 0.126
av node cell to bundle of his cell communication GO:0086067 2 0.126
metal ion homeostasis GO:0055065 189 0.126
insulin secretion GO:0030073 89 0.126
artery development GO:0060840 53 0.124
metanephric mesenchymal cell migration GO:0035789 2 0.123
digestive tract development GO:0048565 190 0.120
positive regulation of mapk cascade GO:0043410 170 0.120
Human
negative regulation of cellular amine metabolic process GO:0033239 1 0.120
actin cytoskeleton organization GO:0030036 220 0.120
Human
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.118
male gamete generation GO:0048232 285 0.117
response to acid chemical GO:0001101 111 0.116
response to peptide GO:1901652 136 0.115
regulation of transmembrane transport GO:0034762 128 0.115
negative regulation of muscle contraction GO:0045932 12 0.114
retina development in camera type eye GO:0060041 119 0.114
positive regulation of protein phosphorylation GO:0001934 242 0.113
gland development GO:0048732 330 0.113
b cell activation GO:0042113 161 0.111
stem cell development GO:0048864 219 0.110
negative regulation of cell motility GO:2000146 61 0.108
Mouse
wound healing GO:0042060 157 0.108
tissue homeostasis GO:0001894 115 0.107
muscle cell differentiation GO:0042692 261 0.107
cell matrix adhesion GO:0007160 68 0.107
regulation of cell projection organization GO:0031344 206 0.107
multi organism reproductive behavior GO:0044705 29 0.107
regulation of secretion by cell GO:1903530 249 0.107
axonogenesis GO:0007409 274 0.106
regulation of peptidyl serine phosphorylation GO:0033135 39 0.106
morphogenesis of embryonic epithelium GO:0016331 159 0.104
hematopoietic progenitor cell differentiation GO:0002244 143 0.104
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.103
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.103
neuron projection guidance GO:0097485 141 0.103
regulation of endothelial cell migration GO:0010594 22 0.103
Human
leukocyte mediated immunity GO:0002443 174 0.102
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.100
photoreceptor cell differentiation GO:0046530 52 0.100
multi multicellular organism process GO:0044706 109 0.100
leukocyte migration GO:0050900 124 0.100
kidney vasculature development GO:0061440 15 0.099
regulation of organ morphogenesis GO:2000027 144 0.098
notch signaling pathway GO:0007219 71 0.098
g protein coupled receptor signaling pathway GO:0007186 243 0.096
b cell differentiation GO:0030183 78 0.095
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.094
detection of mechanical stimulus involved in sensory perception GO:0050974 23 0.093
developmental maturation GO:0021700 193 0.093
sensory perception of mechanical stimulus GO:0050954 107 0.092
axon regeneration GO:0031103 12 0.091
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.090
regulation of actin cytoskeleton organization GO:0032956 84 0.089
Human
multi organism behavior GO:0051705 62 0.089
apical junction assembly GO:0043297 15 0.089
regulation of receptor activity GO:0010469 41 0.088
erk1 and erk2 cascade GO:0070371 77 0.088
Human
blastocyst development GO:0001824 80 0.087
second messenger mediated signaling GO:0019932 73 0.087
regulation of cardiac cell fate specification GO:2000043 1 0.086
multicellular organismal signaling GO:0035637 91 0.086
stem cell proliferation GO:0072089 117 0.085
male sex differentiation GO:0046661 109 0.085
negative regulation of kinase activity GO:0033673 81 0.084
negative regulation of cell proliferation GO:0008285 296 0.084
response to macrophage colony stimulating factor GO:0036005 3 0.084
metanephric glomerular capillary formation GO:0072277 3 0.083
regulation of sphingolipid mediated signaling pathway GO:1902068 2 0.083
stem cell differentiation GO:0048863 268 0.083
negative regulation of immune system process GO:0002683 209 0.082
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.082
positive regulation of cell substrate adhesion GO:0010811 47 0.082
Human
cell activation involved in immune response GO:0002263 126 0.081
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.081
camera type eye development GO:0043010 266 0.081
lens epithelial cell proliferation GO:0097166 1 0.080
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.079
detection of stimulus GO:0051606 84 0.079
response to transforming growth factor beta GO:0071559 88 0.079
filtration diaphragm assembly GO:0036058 1 0.078
mesodermal cell migration GO:0008078 4 0.078
extracellular matrix organization GO:0030198 147 0.077
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.077
peptidyl tyrosine phosphorylation GO:0018108 143 0.076
vasodilation GO:0042311 28 0.076
response to radiation GO:0009314 165 0.076
oligodendrocyte differentiation GO:0048709 53 0.075
small gtpase mediated signal transduction GO:0007264 97 0.075
muscle cell proliferation GO:0033002 52 0.075
negative regulation of glucose transport GO:0010829 9 0.075
cognition GO:0050890 149 0.075
lymphocyte proliferation GO:0046651 164 0.074
positive regulation of vasculogenesis GO:2001214 7 0.073
cellular chemical homeostasis GO:0055082 215 0.073
defense response to other organism GO:0098542 197 0.073
endodermal cell fate specification GO:0001714 4 0.073
negative regulation of endothelial cell apoptotic process GO:2000352 7 0.072
negative regulation of translation GO:0017148 22 0.072
regulation of map kinase activity GO:0043405 120 0.072
endocardial cell differentiation GO:0060956 4 0.072
detection of external stimulus GO:0009581 61 0.072
vascular process in circulatory system GO:0003018 62 0.070
detection of mechanical stimulus involved in equilibrioception GO:0050973 2 0.070
regulation of blood pressure GO:0008217 93 0.070
regulation of transferase activity GO:0051338 263 0.070
Human
regulation of neuron differentiation GO:0045664 281 0.069
cellular response to vascular endothelial growth factor stimulus GO:0035924 11 0.069
regulation of cellular response to growth factor stimulus GO:0090287 82 0.068
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 2 0.068
regulation of hormone levels GO:0010817 211 0.068
regulation of kinase activity GO:0043549 249 0.068
Human
regulation of body fluid levels GO:0050878 162 0.068
endothelium development GO:0003158 45 0.067
negative regulation of protein modification process GO:0031400 163 0.067
regulation of endothelial cell apoptotic process GO:2000351 9 0.067
regulation of anatomical structure size GO:0090066 178 0.067
lymph vessel morphogenesis GO:0036303 11 0.066
response to thyroid hormone GO:0097066 2 0.066
regulation of mitotic cell cycle GO:0007346 126 0.066
purine ribonucleotide metabolic process GO:0009150 290 0.066
skin development GO:0043588 220 0.066
regulation of vesicle mediated transport GO:0060627 139 0.066
negative regulation of blood vessel morphogenesis GO:2000181 25 0.065
Human Mouse
cell type specific apoptotic process GO:0097285 268 0.065
cardiocyte differentiation GO:0035051 87 0.065
positive regulation of nervous system development GO:0051962 221 0.065
regulation of protein serine threonine kinase activity GO:0071900 157 0.065
prostate gland morphogenesis GO:0060512 32 0.064
metanephric glomerulus morphogenesis GO:0072275 3 0.064
epithelial cell proliferation GO:0050673 174 0.064
cell chemotaxis GO:0060326 81 0.064
granulocyte migration GO:0097530 43 0.063
inner ear morphogenesis GO:0042472 101 0.063
regulation of mesenchymal cell proliferation GO:0010464 37 0.062
phosphatidylinositol metabolic process GO:0046488 45 0.062
Human
erythrocyte differentiation GO:0030218 88 0.061
regulation of canonical wnt signaling pathway GO:0060828 82 0.061
regulation of glucose transport GO:0010827 32 0.061
divalent inorganic cation transport GO:0072511 178 0.061
glucose import GO:0046323 32 0.060
detection of abiotic stimulus GO:0009582 60 0.060
angiogenesis involved in coronary vascular morphogenesis GO:0060978 2 0.060
leukocyte chemotaxis GO:0030595 69 0.060
vascular endothelial growth factor signaling pathway GO:0038084 10 0.060
cellular response to abiotic stimulus GO:0071214 56 0.059
protein localization to organelle GO:0033365 185 0.059
glomerular mesangial cell proliferation GO:0072110 3 0.058
learning or memory GO:0007611 148 0.058
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.058
phospholipid metabolic process GO:0006644 87 0.058
Human
regulation of vasculature development GO:1901342 88 0.058
digestive system development GO:0055123 200 0.058
sensory perception GO:0007600 245 0.057
embryonic placenta development GO:0001892 98 0.057
positive regulation of protein modification process GO:0031401 299 0.057
epithelial cell proliferation involved in prostatic bud elongation GO:0060517 1 0.057
nucleotide metabolic process GO:0009117 332 0.057
response to immune response of other organism involved in symbiotic interaction GO:0052564 3 0.056
spinal cord development GO:0021510 81 0.056
spermatid development GO:0007286 108 0.056
regulation of cellular component biogenesis GO:0044087 181 0.055
Human
melanocyte adhesion GO:0097326 1 0.055
transmembrane transport GO:0055085 412 0.055
regulation of leukocyte differentiation GO:1902105 159 0.055
cell migration involved in kidney development GO:0035787 3 0.055
negative regulation of cell adhesion GO:0007162 45 0.055
retina vasculature development in camera type eye GO:0061298 17 0.055
negative regulation of vasculature development GO:1901343 26 0.054
Human Mouse
regulation of chemotaxis GO:0050920 53 0.054
astrocyte fate commitment GO:0060018 4 0.053
production of molecular mediator of immune response GO:0002440 103 0.053
mesenchymal cell proliferation GO:0010463 44 0.053
response to defense related nitric oxide production by other organism involved in symbiotic interaction GO:0052551 2 0.053
protein localization to nucleus GO:0034504 121 0.053
development of primary sexual characteristics GO:0045137 143 0.053
protein kinase b signaling GO:0043491 74 0.052
Human
cell fate commitment GO:0045165 210 0.052
positive regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014718 2 0.052
trabecula formation GO:0060343 24 0.052
nephron epithelium development GO:0072009 92 0.052
cardiac muscle tissue morphogenesis GO:0055008 44 0.052
cardiac muscle tissue development GO:0048738 130 0.051
response to host immune response GO:0052572 3 0.051
osteoclast differentiation GO:0030316 62 0.051
regulation of blood circulation GO:1903522 93 0.051
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.051
leukocyte activation involved in immune response GO:0002366 126 0.051
positive regulation of cytokine secretion involved in immune response GO:0002741 2 0.050
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.050
positive regulation of cell development GO:0010720 237 0.049
organophosphate catabolic process GO:0046434 232 0.049
renal system process GO:0003014 48 0.049
developmental pigmentation GO:0048066 40 0.049
regulation of actin filament based process GO:0032970 99 0.049
Human
ras protein signal transduction GO:0007265 77 0.048
cardiac muscle cell development GO:0055013 39 0.048
ribose phosphate metabolic process GO:0019693 291 0.048
endocardium development GO:0003157 10 0.048
multicellular organismal reproductive behavior GO:0033057 23 0.047
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.047
negative regulation of glucose import GO:0046325 7 0.047
palate development GO:0060021 76 0.047
skeletal system morphogenesis GO:0048705 203 0.046
vegf activated neuropilin signaling pathway GO:0038190 2 0.046
glucose transport GO:0015758 56 0.046
megakaryocyte differentiation GO:0030219 26 0.046
negative regulation of cell migration GO:0030336 59 0.046
Mouse
axon guidance GO:0007411 141 0.045
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.045
cell junction organization GO:0034330 77 0.045
Human
jak stat cascade GO:0007259 42 0.045
primary prostatic bud elongation GO:0060516 2 0.044
homeostasis of number of cells GO:0048872 210 0.044
positive regulation of cell projection organization GO:0031346 95 0.044
hormone metabolic process GO:0042445 86 0.044
cytoplasmic transport GO:0016482 234 0.044
intrahepatic bile duct development GO:0035622 2 0.044
metanephric nephron development GO:0072210 34 0.044
regulation of ion transport GO:0043269 215 0.044
response to amino acid GO:0043200 37 0.044
endocardium formation GO:0060214 4 0.044
cytokine production GO:0001816 319 0.043
positive regulation of secretion by cell GO:1903532 114 0.043
regulation of muscle system process GO:0090257 80 0.043
chemotaxis GO:0006935 247 0.043
olfactory learning GO:0008355 2 0.043
response to defense related host nitric oxide production GO:0052565 2 0.043
t cell differentiation GO:0030217 174 0.042
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.042
regulation of cytokine secretion involved in immune response GO:0002739 4 0.042
negative regulation of smooth muscle contraction GO:0045986 10 0.042
leukocyte differentiation GO:0002521 342 0.042
ascending aorta development GO:0035905 3 0.042
muscle system process GO:0003012 141 0.042
lymphoid progenitor cell differentiation GO:0002320 17 0.042
rho protein signal transduction GO:0007266 32 0.042
ribonucleotide metabolic process GO:0009259 291 0.042
lymphocyte differentiation GO:0030098 242 0.042
macrophage colony stimulating factor signaling pathway GO:0038145 2 0.041
positive chemotaxis GO:0050918 18 0.041
lens development in camera type eye GO:0002088 62 0.041
inorganic ion transmembrane transport GO:0098660 234 0.041
regulation of b cell activation GO:0050864 81 0.041
positive regulation of rho gtpase activity GO:0032321 41 0.041
anatomical structure homeostasis GO:0060249 145 0.041
exocrine system development GO:0035272 45 0.040
regulation of secretion GO:0051046 274 0.040
peptidyl serine phosphorylation GO:0018105 74 0.040
cellular component assembly involved in morphogenesis GO:0010927 139 0.040
purine nucleotide metabolic process GO:0006163 302 0.040
adaptive immune response GO:0002250 155 0.040
mitral valve morphogenesis GO:0003183 4 0.039
epithelium migration GO:0090132 63 0.039
Human
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.039
cell cell junction assembly GO:0007043 27 0.039
myeloid leukocyte differentiation GO:0002573 119 0.038
mesonephric tubule development GO:0072164 94 0.038
regulation of homeostatic process GO:0032844 182 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
dephosphorylation GO:0016311 129 0.038
inner cell mass cellular morphogenesis GO:0001828 1 0.038
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.038
cgmp biosynthetic process GO:0006182 13 0.037
gastrulation with mouth forming second GO:0001702 29 0.037
kidney vasculature morphogenesis GO:0061439 7 0.037
spermatid differentiation GO:0048515 115 0.037
regulation of rho gtpase activity GO:0032319 58 0.037
negative regulation of cell fate specification GO:0009996 4 0.036
purine containing compound biosynthetic process GO:0072522 70 0.036
divalent inorganic cation homeostasis GO:0072507 138 0.036
regulation of membrane potential GO:0042391 192 0.036
negative regulation of protein phosphorylation GO:0001933 126 0.036
negative regulation of cell development GO:0010721 169 0.036
response to stem cell factor GO:0036215 3 0.036
male germ line sex determination GO:0019100 2 0.036
regulation of jak stat cascade GO:0046425 34 0.036
response to heparin GO:0071503 1 0.036
negative regulation of endothelial cell migration GO:0010596 4 0.036
positive regulation of angiogenesis GO:0045766 46 0.036
Human
macromolecule catabolic process GO:0009057 281 0.036
epiblast cell extraembryonic ectoderm cell signaling involved in anterior posterior axis specification GO:0060802 1 0.036
cellular response to cytokine stimulus GO:0071345 189 0.036
negative regulation of b cell differentiation GO:0045578 4 0.036
ribose phosphate biosynthetic process GO:0046390 59 0.035
carbohydrate homeostasis GO:0033500 128 0.035
organonitrogen compound catabolic process GO:1901565 264 0.035
negative regulation of molecular function GO:0044092 258 0.035
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.035
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.035
positive regulation of neuron projection development GO:0010976 79 0.035
negative regulation of angiogenesis GO:0016525 25 0.035
Human Mouse
ear morphogenesis GO:0042471 118 0.035
positive regulation of epithelial cell proliferation GO:0050679 68 0.035
inner ear receptor cell differentiation GO:0060113 61 0.035
regulation of reactive oxygen species metabolic process GO:2000377 40 0.034
regulation of ion transmembrane transport GO:0034765 119 0.034
cellular response to peptide hormone stimulus GO:0071375 92 0.034
negative regulation of heart rate GO:0010459 4 0.034
cytosolic calcium ion homeostasis GO:0051480 70 0.034
endoderm development GO:0007492 45 0.034
cardiac ventricle morphogenesis GO:0003208 50 0.034
blastocyst formation GO:0001825 33 0.034
cardiac cell fate specification GO:0060912 2 0.034
ascending aorta morphogenesis GO:0035910 3 0.034
regulation of positive chemotaxis GO:0050926 7 0.034
action potential GO:0001508 78 0.033
cellular response to lipid GO:0071396 145 0.033
regulation of hematopoietic progenitor cell differentiation GO:1901532 18 0.033
regulation of muscle tissue development GO:1901861 97 0.033
salivary gland morphogenesis GO:0007435 33 0.033
response to hypoxia GO:0001666 58 0.033
positive regulation of cgmp metabolic process GO:0030825 6 0.033
regulation of cellular response to insulin stimulus GO:1900076 30 0.033
nephrogenic mesenchyme development GO:0072076 3 0.033
cell maturation GO:0048469 127 0.033
muscle cell development GO:0055001 133 0.033
negative regulation of protein tyrosine kinase activity GO:0061099 3 0.033
sensory perception of sound GO:0007605 97 0.033
regulation of b cell differentiation GO:0045577 23 0.033
cation transport GO:0006812 399 0.033
guanosine containing compound catabolic process GO:1901069 144 0.033
glial cell differentiation GO:0010001 131 0.033
aorta morphogenesis GO:0035909 22 0.033
cellular response to dna damage stimulus GO:0006974 207 0.032
ear development GO:0043583 200 0.032
regulation of muscle contraction GO:0006937 49 0.032
tyrosine phosphorylation of stat protein GO:0007260 23 0.032
nitrogen compound transport GO:0071705 271 0.032
regulation of reproductive process GO:2000241 66 0.032
purine containing compound metabolic process GO:0072521 311 0.032
smooth muscle tissue development GO:0048745 22 0.032
defense response to bacterium GO:0042742 119 0.032
activation of immune response GO:0002253 138 0.032
t cell activation involved in immune response GO:0002286 43 0.032
calcium ion transport GO:0006816 159 0.032
monosaccharide transport GO:0015749 58 0.032
regulation of skeletal muscle fiber development GO:0048742 36 0.031
morphogenesis of a branching epithelium GO:0061138 193 0.031
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.031
Human
cardiac atrium development GO:0003230 24 0.031
response to extracellular stimulus GO:0009991 127 0.031
regulation of cell cycle GO:0051726 281 0.031
regulation of morphogenesis of a branching structure GO:0060688 53 0.031
heart process GO:0003015 94 0.031
cyclic nucleotide metabolic process GO:0009187 59 0.031
heart trabecula morphogenesis GO:0061384 26 0.031
cellularization GO:0007349 1 0.031
metanephros development GO:0001656 79 0.031
nuclear transport GO:0051169 139 0.031
transmission of nerve impulse GO:0019226 76 0.031
regulation of heart contraction GO:0008016 77 0.031
phosphatidylinositol phosphorylation GO:0046854 23 0.031
Human
positive regulation of growth GO:0045927 104 0.031
peptide secretion GO:0002790 114 0.030
mesenchymal cell differentiation GO:0048762 107 0.030
mesoderm development GO:0007498 100 0.030
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.030
Human
positive regulation of neuron differentiation GO:0045666 141 0.030
cell migration involved in gastrulation GO:0042074 13 0.030
negative regulation of mesodermal cell fate specification GO:0042662 3 0.030
epidermis development GO:0008544 187 0.030
mesenchyme development GO:0060485 152 0.030
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.030
metanephric glomerular endothelium development GO:0072264 1 0.030

Tek disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.106
disease of anatomical entity DOID:7 0 0.106
hematopoietic system disease DOID:74 0 0.106
hemolytic anemia DOID:583 0 0.083
hemolytic uremic syndrome DOID:12554 0 0.083
normocytic anemia DOID:720 0 0.083
anemia DOID:2355 0 0.083
muscular disease DOID:0080000 0 0.034
musculoskeletal system disease DOID:17 0 0.034
myopathy DOID:423 0 0.030
muscle tissue disease DOID:66 0 0.030