Mus musculus

38 known processes

Tgfa

transforming growth factor alpha

(Aliases: wa1,wa-1)

Tgfa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hair follicle development GO:0001942 85 0.944
epithelial tube morphogenesis GO:0060562 303 0.942
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.852
stem cell development GO:0048864 219 0.840
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.801
regulation of cellular amino acid metabolic process GO:0006521 5 0.777
positive regulation of cellular amine metabolic process GO:0033240 5 0.776
regulation of transferase activity GO:0051338 263 0.747
Human
epidermis development GO:0008544 187 0.742
regulation of cell migration GO:0030334 219 0.737
regulation of protein kinase activity GO:0045859 232 0.736
Human
hair cycle GO:0042633 90 0.730
positive regulation of protein kinase activity GO:0045860 144 0.718
Human
cellular amino acid metabolic process GO:0006520 103 0.713
positive regulation of rho gtpase activity GO:0032321 41 0.700
regulation of cellular ketone metabolic process GO:0010565 66 0.689
stem cell maintenance GO:0019827 130 0.684
hair follicle morphogenesis GO:0031069 29 0.672
mapk cascade GO:0000165 281 0.660
Human
skin development GO:0043588 220 0.643
stem cell differentiation GO:0048863 268 0.637
positive regulation of transferase activity GO:0051347 167 0.631
Human
regulation of cell motility GO:2000145 236 0.620
somatic stem cell maintenance GO:0035019 47 0.617
morphogenesis of a branching epithelium GO:0061138 193 0.616
regulation of kinase activity GO:0043549 249 0.611
Human
forebrain development GO:0030900 302 0.610
regulation of cellular amine metabolic process GO:0033238 20 0.601
positive regulation of kinase activity GO:0033674 155 0.590
Human
positive regulation of intracellular transport GO:0032388 70 0.576
g protein coupled receptor signaling pathway GO:0007186 243 0.562
ameboidal type cell migration GO:0001667 128 0.561
response to organonitrogen compound GO:0010243 246 0.532
axis elongation involved in somitogenesis GO:0090245 4 0.514
regulation of hormone levels GO:0010817 211 0.510
cerebral cortex development GO:0021987 86 0.494
non canonical wnt signaling pathway GO:0035567 33 0.485
positive regulation of mapk cascade GO:0043410 170 0.480
Human
negative regulation of cell proliferation GO:0008285 296 0.475
regulation of protein serine threonine kinase activity GO:0071900 157 0.466
Human
regulation of protein tyrosine kinase activity GO:0061097 17 0.466
Human
regulation of mapk cascade GO:0043408 248 0.458
Human
epidermis morphogenesis GO:0048730 33 0.458
canonical wnt signaling pathway GO:0060070 130 0.453
cellular amine metabolic process GO:0044106 44 0.451
blood circulation GO:0008015 195 0.451
leukocyte differentiation GO:0002521 342 0.451
lymphocyte differentiation GO:0030098 242 0.434
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.427
Human
apoptotic signaling pathway GO:0097190 306 0.424
molting cycle GO:0042303 90 0.422
positive regulation of protein phosphorylation GO:0001934 242 0.419
Human
ossification GO:0001503 216 0.415
regulation of map kinase activity GO:0043405 120 0.412
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.410
positive regulation of epidermal growth factor activated receptor activity GO:0045741 2 0.409
Human
positive regulation of map kinase activity GO:0043406 84 0.405
Human
epidermal growth factor receptor signaling pathway GO:0007173 28 0.401
morphogenesis of a branching structure GO:0001763 203 0.399
regulation of epithelial cell proliferation GO:0050678 141 0.399
Human
positive regulation of cell migration GO:0030335 109 0.394
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.392
embryonic organ morphogenesis GO:0048562 276 0.384
regulation of wnt signaling pathway GO:0030111 123 0.383
regulation of cell activation GO:0050865 289 0.373
epithelial cell proliferation GO:0050673 174 0.372
Human
mammary gland morphogenesis GO:0060443 54 0.366
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.363
insulin secretion GO:0030073 89 0.361
morphogenesis of a polarized epithelium GO:0001738 37 0.356
positive regulation of wnt signaling pathway GO:0030177 45 0.352
regulation of epidermal growth factor activated receptor activity GO:0007176 7 0.351
Human
wnt signaling pathway GO:0016055 188 0.341
regulation of cytoskeleton organization GO:0051493 122 0.340
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.335
mammary gland duct morphogenesis GO:0060603 38 0.335
circulatory system process GO:0003013 197 0.333
regulation of epithelial cell migration GO:0010632 35 0.333
axis elongation GO:0003401 30 0.331
hormone secretion GO:0046879 128 0.330
positive regulation of gtp catabolic process GO:0033126 85 0.325
neural tube development GO:0021915 160 0.324
skin morphogenesis GO:0043589 38 0.323
actin cytoskeleton organization GO:0030036 220 0.319
skeletal system development GO:0001501 356 0.311
establishment of planar polarity GO:0001736 28 0.311
axonogenesis GO:0007409 274 0.309
regulation of establishment of planar polarity GO:0090175 28 0.308
regulation of defense response GO:0031347 233 0.307
cerebral cortex cell migration GO:0021795 44 0.302
camera type eye development GO:0043010 266 0.300
branch elongation of an epithelium GO:0060602 19 0.288
gland development GO:0048732 330 0.286
muscle cell proliferation GO:0033002 52 0.281
keratinocyte differentiation GO:0030216 48 0.277
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.274
positive regulation of protein modification process GO:0031401 299 0.274
Human
negative regulation of cell migration GO:0030336 59 0.273
branching morphogenesis of an epithelial tube GO:0048754 159 0.271
epithelium migration GO:0090132 63 0.271
transmembrane transport GO:0055085 412 0.267
synapse organization GO:0050808 125 0.266
cardiac ventricle development GO:0003231 83 0.264
regulation of receptor activity GO:0010469 41 0.264
Human
positive regulation of cellular catabolic process GO:0031331 148 0.264
activation of mapkk activity GO:0000186 15 0.263
morphogenesis of an epithelial fold GO:0060571 28 0.259
angiogenesis GO:0001525 201 0.254
negative regulation of hydrolase activity GO:0051346 71 0.252
protein maturation GO:0051604 176 0.249
carbohydrate derivative biosynthetic process GO:1901137 183 0.247
peptide hormone secretion GO:0030072 109 0.247
t cell differentiation GO:0030217 174 0.247
t cell differentiation in thymus GO:0033077 77 0.247
positive regulation of apoptotic process GO:0043065 217 0.246
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.246
amine metabolic process GO:0009308 45 0.244
mesenchyme development GO:0060485 152 0.244
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.243
regulation of neural precursor cell proliferation GO:2000177 70 0.243
regulation of canonical wnt signaling pathway GO:0060828 82 0.242
extrinsic apoptotic signaling pathway GO:0097191 126 0.241
cellular ketone metabolic process GO:0042180 84 0.240
negative regulation of ossification GO:0030279 49 0.238
cellular homeostasis GO:0019725 240 0.237
ureteric bud development GO:0001657 94 0.235
regulation of ossification GO:0030278 112 0.234
regionalization GO:0003002 337 0.234
regulation of response to wounding GO:1903034 189 0.231
establishment of tissue polarity GO:0007164 28 0.228
bone remodeling GO:0046849 53 0.227
ras protein signal transduction GO:0007265 77 0.227
response to peptide GO:1901652 136 0.226
heart morphogenesis GO:0003007 178 0.221
morphogenesis of an epithelial sheet GO:0002011 27 0.219
positive regulation of neural precursor cell proliferation GO:2000179 42 0.219
regulation of cell adhesion GO:0030155 154 0.214
cardiac septum morphogenesis GO:0060411 46 0.213
genitalia development GO:0048806 37 0.213
regulation of nucleotide metabolic process GO:0006140 169 0.213
digestive tract morphogenesis GO:0048546 147 0.212
telencephalon cell migration GO:0022029 55 0.211
cellular response to hormone stimulus GO:0032870 150 0.211
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.210
ear morphogenesis GO:0042471 118 0.210
regulation of postsynaptic membrane potential GO:0060078 48 0.208
positive regulation of epithelial cell migration GO:0010634 19 0.208
central nervous system morphogenesis GO:0021551 2 0.207
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.206
rho protein signal transduction GO:0007266 32 0.206
peptidyl amino acid modification GO:0018193 336 0.205
Human
negative regulation of cell motility GO:2000146 61 0.205
mammary gland epithelium development GO:0061180 65 0.204
cation transport GO:0006812 399 0.203
positive regulation of cytoplasmic transport GO:1903651 40 0.203
positive regulation of apoptotic signaling pathway GO:2001235 95 0.203
mesonephric tubule development GO:0072164 94 0.201
paraxial mesodermal cell fate commitment GO:0048343 2 0.201
positive regulation of protein import into nucleus GO:0042307 26 0.200
positive regulation of nucleotide metabolic process GO:0045981 114 0.199
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.198
negative regulation of molecular function GO:0044092 258 0.198
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.198
cardiac chamber morphogenesis GO:0003206 93 0.197
tissue migration GO:0090130 68 0.196
pallium development GO:0021543 120 0.195
tissue remodeling GO:0048771 102 0.194
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.193
cardiac septum development GO:0003279 59 0.192
small gtpase mediated signal transduction GO:0007264 97 0.191
regulation of apoptotic signaling pathway GO:2001233 197 0.190
determination of heart left right asymmetry GO:0061371 48 0.189
regulation of transforming growth factor beta2 production GO:0032909 2 0.188
regulation of rho gtpase activity GO:0032319 58 0.188
t cell activation GO:0042110 289 0.187
regulation of catenin import into nucleus GO:0035412 5 0.187
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.187
nucleoside phosphate metabolic process GO:0006753 338 0.187
organonitrogen compound biosynthetic process GO:1901566 192 0.187
epithelial cell migration GO:0010631 63 0.184
response to extracellular stimulus GO:0009991 127 0.184
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.183
positive regulation of ras gtpase activity GO:0032320 65 0.183
regulation of ion homeostasis GO:2000021 64 0.180
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.179
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.178
anatomical structure homeostasis GO:0060249 145 0.178
artery development GO:0060840 53 0.177
negative regulation of phosphorus metabolic process GO:0010563 184 0.176
telencephalon development GO:0021537 186 0.175
anagen GO:0042640 13 0.175
inner ear morphogenesis GO:0042472 101 0.174
placenta development GO:0001890 140 0.174
negative regulation of cellular protein metabolic process GO:0032269 247 0.173
digestive system development GO:0055123 200 0.173
gtp catabolic process GO:0006184 143 0.170
sterol metabolic process GO:0016125 58 0.169
blood vessel morphogenesis GO:0048514 285 0.167
regulation of cytoplasmic transport GO:1903649 112 0.166
dopaminergic neuron differentiation GO:0071542 14 0.165
regulation of proteolysis GO:0030162 164 0.165
bone resorption GO:0045453 38 0.163
cardiac muscle tissue development GO:0048738 130 0.162
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.162
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.162
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.161
regulation of protein transport GO:0051223 163 0.161
regulation of homeostatic process GO:0032844 182 0.160
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.160
neural tube formation GO:0001841 108 0.160
lipid biosynthetic process GO:0008610 179 0.160
oxygen homeostasis GO:0032364 2 0.157
regulation of actin filament based process GO:0032970 99 0.157
embryonic epithelial tube formation GO:0001838 130 0.157
nitrogen compound transport GO:0071705 271 0.156
male gamete generation GO:0048232 285 0.152
positive regulation of cell cycle GO:0045787 92 0.152
Human
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.152
Human
carboxylic acid biosynthetic process GO:0046394 86 0.152
wound healing GO:0042060 157 0.152
Rat
male sex differentiation GO:0046661 109 0.151
neuroblast proliferation GO:0007405 49 0.151
primary neural tube formation GO:0014020 95 0.147
membrane organization GO:0061024 245 0.143
regulation of hormone secretion GO:0046883 88 0.143
paraxial mesodermal cell differentiation GO:0048342 2 0.141
cellular response to external stimulus GO:0071496 88 0.140
positive regulation of cell development GO:0010720 237 0.139
embryonic heart tube morphogenesis GO:0003143 51 0.138
cardiac chamber development GO:0003205 108 0.137
positive regulation of cell cell adhesion mediated by cadherin GO:2000049 2 0.137
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.137
Human
intracellular protein transport GO:0006886 204 0.136
positive regulation of nervous system development GO:0051962 221 0.136
mesonephros development GO:0001823 97 0.135
urogenital system development GO:0001655 261 0.134
negative regulation of inflammatory response GO:0050728 61 0.134
regulation of peptide transport GO:0090087 91 0.133
respiratory system development GO:0060541 190 0.132
regulation of hydrolase activity GO:0051336 246 0.131
skeletal system morphogenesis GO:0048705 203 0.131
determination of left right symmetry GO:0007368 80 0.130
steroid metabolic process GO:0008202 119 0.129
cellular response to growth factor stimulus GO:0071363 197 0.128
forebrain cell migration GO:0021885 58 0.128
appendage morphogenesis GO:0035107 149 0.128
stem cell proliferation GO:0072089 117 0.128
positive regulation of intracellular protein transport GO:0090316 42 0.127
regulation of osteoblast differentiation GO:0045667 67 0.127
purine containing compound metabolic process GO:0072521 311 0.127
lung induction GO:0060492 3 0.126
regulation of system process GO:0044057 200 0.125
forebrain generation of neurons GO:0021872 63 0.124
gtp metabolic process GO:0046039 144 0.124
regulation of inflammatory response GO:0050727 147 0.124
aminoglycan metabolic process GO:0006022 34 0.124
organic hydroxy compound metabolic process GO:1901615 203 0.123
negative regulation of protein metabolic process GO:0051248 282 0.122
positive regulation of receptor activity GO:2000273 17 0.122
Human
jnk cascade GO:0007254 72 0.122
stress activated mapk cascade GO:0051403 80 0.122
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.122
ion transmembrane transport GO:0034220 361 0.122
regulation of t cell activation GO:0050863 170 0.119
planar cell polarity pathway involved in neural tube closure GO:0090179 14 0.116
regulation of purine nucleotide metabolic process GO:1900542 169 0.116
regulation of kidney development GO:0090183 40 0.115
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.115
regulation of cellular response to growth factor stimulus GO:0090287 82 0.114
regulation of protein targeting GO:1903533 61 0.113
limb development GO:0060173 166 0.113
ear development GO:0043583 200 0.113
outflow tract morphogenesis GO:0003151 53 0.112
ribose phosphate metabolic process GO:0019693 291 0.112
male gonad development GO:0008584 88 0.111
protein localization to organelle GO:0033365 185 0.110
mammary gland lobule development GO:0061377 22 0.110
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.109
regulation of nucleocytoplasmic transport GO:0046822 73 0.109
stress activated protein kinase signaling cascade GO:0031098 81 0.109
muscle tissue development GO:0060537 308 0.107
epithelial tube formation GO:0072175 130 0.107
peptide secretion GO:0002790 114 0.107
positive regulation of protein localization to nucleus GO:1900182 30 0.106
positive regulation of cell motility GO:2000147 116 0.106
organic acid biosynthetic process GO:0016053 86 0.106
regulation of secretion by cell GO:1903530 249 0.105
regulation of organ morphogenesis GO:2000027 144 0.105
negative regulation of wnt signaling pathway GO:0030178 73 0.105
regulation of gtp catabolic process GO:0033124 113 0.104
apoptotic process involved in development GO:1902742 28 0.104
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.103
positive regulation of jnk cascade GO:0046330 46 0.103
peptide transport GO:0015833 133 0.103
regulation of leukocyte proliferation GO:0070663 121 0.103
inflammatory response GO:0006954 244 0.103
cognition GO:0050890 149 0.103
forebrain neuroblast division GO:0021873 9 0.102
gliogenesis GO:0042063 141 0.102
organic anion transport GO:0015711 137 0.102
negative regulation of cellular amine metabolic process GO:0033239 1 0.101
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.101
alcohol metabolic process GO:0006066 116 0.100
tissue regeneration GO:0042246 22 0.100
regulation of heart contraction GO:0008016 77 0.100
endothelial cell migration GO:0043542 44 0.100
cell adhesion GO:0007155 329 0.099
regulation of renal sodium excretion GO:0035813 3 0.098
regulation of protein localization GO:0032880 231 0.097
cartilage development GO:0051216 140 0.097
bmp signaling pathway GO:0030509 93 0.097
nucleoside metabolic process GO:0009116 246 0.097
protein kinase b signaling GO:0043491 74 0.096
negative regulation of epithelial cell proliferation GO:0050680 64 0.096
regulation of intracellular transport GO:0032386 159 0.096
protein processing GO:0016485 163 0.096
lymphocyte homeostasis GO:0002260 64 0.095
regulation of muscle tissue development GO:1901861 97 0.095
renal system development GO:0072001 225 0.094
tube closure GO:0060606 91 0.093
organ growth GO:0035265 117 0.093
regulation of protein catabolic process GO:0042176 108 0.093
hormone metabolic process GO:0042445 86 0.092
positive regulation of programmed cell death GO:0043068 218 0.092
negative regulation of neuron differentiation GO:0045665 101 0.092
striated muscle tissue development GO:0014706 293 0.092
renal vesicle induction GO:0072034 3 0.092
protein localization to nucleus GO:0034504 121 0.092
guanosine containing compound catabolic process GO:1901069 144 0.091
regulation of stress activated mapk cascade GO:0032872 69 0.091
endocrine system development GO:0035270 98 0.091
positive regulation of cell adhesion GO:0045785 80 0.090
ribonucleotide metabolic process GO:0009259 291 0.090
regulation of stem cell proliferation GO:0072091 78 0.090
negative regulation of cellular component organization GO:0051129 194 0.089
embryonic appendage morphogenesis GO:0035113 126 0.089
single organism cell adhesion GO:0098602 156 0.089
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.089
cardiac right atrium morphogenesis GO:0003213 3 0.089
regulation of leukocyte differentiation GO:1902105 159 0.089
cellular response to extracellular stimulus GO:0031668 81 0.088
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.088
positive regulation of response to wounding GO:1903036 66 0.087
developmental cell growth GO:0048588 84 0.087
purine ribonucleoside metabolic process GO:0046128 241 0.087
cardiac atrium morphogenesis GO:0003209 23 0.086
morphogenesis of embryonic epithelium GO:0016331 159 0.086
midbrain development GO:0030901 35 0.086
response to oxidative stress GO:0006979 123 0.086
protein import into nucleus GO:0006606 95 0.086
mesonephric duct formation GO:0072181 2 0.086
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.085
positive regulation of stress activated mapk cascade GO:0032874 48 0.085
androgen biosynthetic process GO:0006702 4 0.085
metencephalon development GO:0022037 89 0.085
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.084
actin filament organization GO:0007015 113 0.084
purine nucleotide metabolic process GO:0006163 302 0.084
polarity specification of proximal distal axis GO:0010085 2 0.083
nuclear import GO:0051170 95 0.082
response to growth factor GO:0070848 198 0.082
developmental programmed cell death GO:0010623 41 0.082
single organism nuclear import GO:1902593 95 0.081
purine ribonucleotide metabolic process GO:0009150 290 0.081
positive regulation of protein tyrosine kinase activity GO:0061098 10 0.081
Human
head morphogenesis GO:0060323 34 0.080
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.079
somite development GO:0061053 81 0.079
ribonucleoside metabolic process GO:0009119 245 0.079
glucose homeostasis GO:0042593 128 0.078
cell proliferation in external granule layer GO:0021924 10 0.078
positive regulation of neuron projection development GO:0010976 79 0.078
locomotory behavior GO:0007626 195 0.078
response to organic cyclic compound GO:0014070 198 0.078
trachea cartilage morphogenesis GO:0060535 4 0.077
rac protein signal transduction GO:0016601 13 0.076
hair cycle phase GO:0044851 16 0.076
nephric duct formation GO:0072179 4 0.076
regulation of cardioblast differentiation GO:0051890 3 0.076
regulation of cell growth GO:0001558 91 0.075
cell junction organization GO:0034330 77 0.075
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.074
ventricular septum development GO:0003281 42 0.074
regulation of body fluid levels GO:0050878 162 0.074
regulation of purine nucleotide catabolic process GO:0033121 122 0.074
regulation of peptidyl threonine phosphorylation GO:0010799 12 0.074
tube formation GO:0035148 140 0.074
positive regulation of proteolysis GO:0045862 85 0.074
maintenance of cell number GO:0098727 3 0.073
regulation of mesenchymal cell proliferation GO:0010464 37 0.073
salivary gland morphogenesis GO:0007435 33 0.073
appendage development GO:0048736 166 0.073
neural tube closure GO:0001843 90 0.073
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.072
mesonephric duct morphogenesis GO:0072180 4 0.072
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.072
negative regulation of cell development GO:0010721 169 0.072
hindbrain formation GO:0021576 1 0.072
bone development GO:0060348 120 0.072
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.072
developmental growth involved in morphogenesis GO:0060560 138 0.072
response to steroid hormone GO:0048545 56 0.071
mesenchymal cell differentiation GO:0048762 107 0.071
regulation of establishment of protein localization GO:0070201 181 0.071
glycosaminoglycan metabolic process GO:0030203 34 0.070
positive regulation of protein transport GO:0051222 93 0.070
inorganic cation transmembrane transport GO:0098662 207 0.070
macromolecule catabolic process GO:0009057 281 0.070
muscle cell differentiation GO:0042692 261 0.070
regulation of cellular catabolic process GO:0031329 242 0.069
epithelial cell differentiation involved in mammary gland alveolus development GO:0061030 4 0.069
aromatic compound catabolic process GO:0019439 286 0.068
positive regulation of ossification GO:0045778 47 0.068
leukocyte apoptotic process GO:0071887 71 0.068
regulation of secretion GO:0051046 274 0.067
regulation of bmp signaling pathway GO:0030510 60 0.067
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.067
mitral valve development GO:0003174 4 0.067
positive regulation of hydrolase activity GO:0051345 148 0.067
oviduct development GO:0060066 3 0.066
negative regulation of cell growth GO:0030308 44 0.066
kidney development GO:0001822 213 0.066
negative regulation of immune system process GO:0002683 209 0.066
extracellular structure organization GO:0043062 148 0.065
positive regulation of cell death GO:0010942 224 0.065
cell matrix adhesion GO:0007160 68 0.065
negative regulation of growth GO:0045926 99 0.065
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.065
neural precursor cell proliferation GO:0061351 121 0.065
epithelial to mesenchymal transition GO:0001837 47 0.065
positive regulation of camp mediated signaling GO:0043950 3 0.064
mesoderm development GO:0007498 100 0.064
t cell apoptotic process GO:0070231 39 0.064
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.064
regulation of cell cycle GO:0051726 281 0.064
Human
single organismal cell cell adhesion GO:0016337 131 0.064
nucleotide metabolic process GO:0009117 332 0.064
alpha beta t cell activation GO:0046631 91 0.063
lymphocyte apoptotic process GO:0070227 54 0.063
gastrulation GO:0007369 116 0.063
regulation of peptidase activity GO:0052547 96 0.063
regulation of protein import into nucleus GO:0042306 52 0.063
cytokine mediated signaling pathway GO:0019221 115 0.063
developmental maturation GO:0021700 193 0.062
negative regulation of neuron projection development GO:0010977 50 0.062
endothelial cell differentiation GO:0045446 41 0.062
carbohydrate metabolic process GO:0005975 230 0.062
amide transport GO:0042886 138 0.062
regulation of endothelial cell migration GO:0010594 22 0.062
regulation of protein maturation GO:1903317 96 0.062
renal inner medulla development GO:0072053 3 0.062
divalent inorganic cation transport GO:0072511 178 0.061
hindbrain development GO:0030902 128 0.061
foregut regionalization GO:0060423 3 0.061
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.060
endocrine process GO:0050886 39 0.060
mechanoreceptor differentiation GO:0042490 67 0.060
regulation of intracellular protein transport GO:0033157 82 0.060
regulation of epidermal cell differentiation GO:0045604 21 0.060
mesenchymal cell proliferation GO:0010463 44 0.060
mesonephric epithelium development GO:0072163 94 0.060
gas homeostasis GO:0033483 3 0.059
purine ribonucleotide catabolic process GO:0009154 208 0.059
positive regulation of epithelial cell proliferation GO:0050679 68 0.059
Human
renal outer medulla development GO:0072054 2 0.059
adult behavior GO:0030534 135 0.059
regulation of muscle contraction GO:0006937 49 0.059
positive regulation of nucleoside metabolic process GO:0045979 91 0.058
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.058
carbohydrate homeostasis GO:0033500 128 0.058
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.058
limb morphogenesis GO:0035108 149 0.058
rhythmic process GO:0048511 174 0.058
positive regulation of gtpase activity GO:0043547 85 0.058
modification dependent macromolecule catabolic process GO:0043632 133 0.058
peptidyl tyrosine modification GO:0018212 145 0.058
Human
regulation of lymphocyte activation GO:0051249 240 0.057
paraxial mesoderm development GO:0048339 18 0.057
cellular chemical homeostasis GO:0055082 215 0.057
positive regulation of catenin import into nucleus GO:0035413 2 0.057
regulation of epidermis development GO:0045682 33 0.057
positive regulation of protein catabolic process GO:0045732 60 0.056
cation transmembrane transport GO:0098655 266 0.056
epithelial cell proliferation involved in mammary gland duct elongation GO:0060750 5 0.056
regulation of mitotic cell cycle GO:0007346 126 0.056
Human
regulation of heart morphogenesis GO:2000826 22 0.056
cellular divalent inorganic cation homeostasis GO:0072503 127 0.055
positive regulation of secretion by cell GO:1903532 114 0.055
regulation of vasculature development GO:1901342 88 0.055
lung field specification GO:0060424 3 0.055
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.055
endoderm development GO:0007492 45 0.055
digestive tract development GO:0048565 190 0.054

Tgfa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.075
musculoskeletal system disease DOID:17 0 0.075