Mus musculus

461 known processes

Tgfb1

transforming growth factor, beta 1

(Aliases: TGF-beta1,Tgfb,TGFbeta1,Tgfb-1)

Tgfb1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amine metabolic process GO:0033238 20 0.999
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.997
leukocyte differentiation GO:0002521 342 0.996
activation of janus kinase activity GO:0042976 2 0.996
positive regulation of apoptotic signaling pathway GO:2001235 95 0.995
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.994
Human
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.994
Mouse
t cell differentiation GO:0030217 174 0.993
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.992
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.991
Human
lymphocyte differentiation GO:0030098 242 0.991
response to host GO:0075136 3 0.988
Human
extrinsic apoptotic signaling pathway GO:0097191 126 0.977
Human Mouse
leukocyte proliferation GO:0070661 172 0.975
negative regulation of interferon gamma mediated signaling pathway GO:0060336 1 0.973
cell substrate adhesion GO:0031589 130 0.972
regulation of melanocyte differentiation GO:0045634 7 0.971
response to organic cyclic compound GO:0014070 198 0.969
Human Mouse Rat
response to osmotic stress GO:0006970 21 0.968
positive regulation of apoptotic process GO:0043065 217 0.965
Mouse Rat
apoptotic signaling pathway GO:0097190 306 0.965
Human Mouse
negative regulation of growth GO:0045926 99 0.964
digestive tract development GO:0048565 190 0.964
Rat
regulation of cell shape GO:0008360 39 0.962
lymphocyte proliferation GO:0046651 164 0.957
regulation of myeloid cell differentiation GO:0045637 96 0.952
cellular amino acid metabolic process GO:0006520 103 0.952
response to alcohol GO:0097305 48 0.950
Human Mouse Rat
myeloid leukocyte differentiation GO:0002573 119 0.950
positive regulation of protein modification process GO:0031401 299 0.950
cellular response to growth factor stimulus GO:0071363 197 0.947
fat soluble vitamin biosynthetic process GO:0042362 4 0.946
sensory perception of umami taste GO:0050917 4 0.945
cellular response to peptide GO:1901653 92 0.945
urogenital system development GO:0001655 261 0.944
cytokine production GO:0001816 319 0.943
axon guidance GO:0007411 141 0.940
Mouse Fly
branching morphogenesis of an epithelial tube GO:0048754 159 0.940
stem cell differentiation GO:0048863 268 0.938
positive regulation of leukocyte proliferation GO:0070665 73 0.937
cellular response to peptide hormone stimulus GO:0071375 92 0.937
regulation of vitamin d biosynthetic process GO:0060556 1 0.936
positive regulation of cell death GO:0010942 224 0.934
Mouse Rat
ovulation cycle GO:0042698 59 0.933
response to lipopolysaccharide GO:0032496 128 0.929
Human
metanephric glomerular mesangium development GO:0072223 3 0.927
regulation of myeloid leukocyte differentiation GO:0002761 58 0.927
gland development GO:0048732 330 0.926
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.923
Human
regulation of cellular amino acid metabolic process GO:0006521 5 0.923
carbohydrate derivative biosynthetic process GO:1901137 183 0.920
Human
cartilage development GO:0051216 140 0.915
peptidyl amino acid modification GO:0018193 336 0.915
rhythmic process GO:0048511 174 0.915
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.912
regulation of cellular ketone metabolic process GO:0010565 66 0.911
positive regulation of kinase activity GO:0033674 155 0.908
Human
action potential GO:0001508 78 0.906
Rat
digestive system development GO:0055123 200 0.903
Rat
negative regulation of cell proliferation GO:0008285 296 0.903
negative regulation of leukocyte differentiation GO:1902106 51 0.900
t cell activation GO:0042110 289 0.898
positive regulation of cell migration GO:0030335 109 0.897
Human
regulation of insulin receptor signaling pathway GO:0046626 21 0.893
muscle cell differentiation GO:0042692 261 0.888
Human Rat
regulation of developmental pigmentation GO:0048070 14 0.887
positive regulation of leukocyte differentiation GO:1902107 86 0.879
regulation of lymphocyte activation GO:0051249 240 0.876
negative regulation of apoptotic signaling pathway GO:2001234 104 0.874
positive regulation of programmed cell death GO:0043068 218 0.874
Mouse Rat
superoxide metabolic process GO:0006801 27 0.873
Human
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 2 0.873
granulocyte chemotaxis GO:0071621 39 0.872
connective tissue development GO:0061448 179 0.868
erythrocyte differentiation GO:0030218 88 0.868
positive regulation of cell development GO:0010720 237 0.868
cellular component assembly involved in morphogenesis GO:0010927 139 0.866
amine metabolic process GO:0009308 45 0.864
pigment cell differentiation GO:0050931 27 0.860
regulation of cell migration GO:0030334 219 0.855
Human
sphingolipid metabolic process GO:0006665 45 0.854
cell chemotaxis GO:0060326 81 0.853
cytokine mediated signaling pathway GO:0019221 115 0.851
negative regulation of protein metabolic process GO:0051248 282 0.851
Human
regulation of leukocyte differentiation GO:1902105 159 0.850
activation of rac gtpase activity GO:0032863 2 0.847
response to amino acid GO:0043200 37 0.847
myeloid leukocyte migration GO:0097529 57 0.842
vitamin d biosynthetic process GO:0042368 3 0.841
cellular response to organonitrogen compound GO:0071417 145 0.839
cell adhesion GO:0007155 329 0.837
Human
molting cycle GO:0042303 90 0.836
Mouse
regulation of osteoclast differentiation GO:0045670 36 0.835
regulation of apoptotic signaling pathway GO:2001233 197 0.834
Mouse
jak stat cascade GO:0007259 42 0.830
lamellipodium organization GO:0097581 29 0.830
regulation of gluconeogenesis GO:0006111 30 0.829
negative regulation of peptide hormone secretion GO:0090278 16 0.829
positive regulation of protein phosphorylation GO:0001934 242 0.828
Human
cellular response to organic cyclic compound GO:0071407 87 0.820
Human Mouse Rat
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.818
embryonic organ morphogenesis GO:0048562 276 0.811
ensheathment of neurons GO:0007272 76 0.811
Rat
development of primary female sexual characteristics GO:0046545 73 0.810
neuronal action potential GO:0019228 54 0.800
Rat
positive regulation of lymphocyte proliferation GO:0050671 70 0.798
morphogenesis of a branching epithelium GO:0061138 193 0.796
cellular amine metabolic process GO:0044106 44 0.790
calcium ion transport GO:0006816 159 0.789
Rat
regulation of lipid metabolic process GO:0019216 118 0.789
Human
reactive oxygen species biosynthetic process GO:1903409 8 0.788
reactive nitrogen species metabolic process GO:2001057 0 0.781
tyrosine phosphorylation of stat3 protein GO:0042503 12 0.774
hormone mediated signaling pathway GO:0009755 23 0.773
small gtpase mediated signal transduction GO:0007264 97 0.773
establishment of endothelial blood brain barrier GO:0014045 3 0.772
apoptotic process involved in mammary gland involution GO:0060057 4 0.772
response to transforming growth factor beta GO:0071559 88 0.771
cellular response to inorganic substance GO:0071241 37 0.770
positive regulation of b cell proliferation GO:0030890 24 0.770
epithelial cell proliferation GO:0050673 174 0.769
Human Rat
developmental maturation GO:0021700 193 0.769
Mouse
developmental pigmentation GO:0048066 40 0.768
cellular response to lipid GO:0071396 145 0.767
Human Mouse Rat
fibroblast proliferation GO:0048144 35 0.756
oxidation reduction process GO:0055114 342 0.754
positive regulation of smooth muscle cell migration GO:0014911 4 0.745
positive regulation of osteoclast differentiation GO:0045672 15 0.742
steroid metabolic process GO:0008202 119 0.740
hypotonic response GO:0006971 3 0.738
replacement ossification GO:0036075 26 0.737
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.735
regulation of kinase activity GO:0043549 249 0.734
Human
regulation of lipid kinase activity GO:0043550 14 0.734
Human
circulatory system process GO:0003013 197 0.734
stem cell maintenance GO:0019827 130 0.728
regulation of activation of jak2 kinase activity GO:0010534 1 0.727
ras protein signal transduction GO:0007265 77 0.726
positive regulation of transferase activity GO:0051347 167 0.725
Human
regulation of mast cell differentiation GO:0060375 3 0.722
leukocyte migration GO:0050900 124 0.720
positive regulation of t cell proliferation GO:0042102 52 0.719
embryonic hemopoiesis GO:0035162 23 0.718
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.716
regulation of epithelial cell proliferation GO:0050678 141 0.716
Human Rat
regulation of nitrogen cycle metabolic process GO:1903314 1 0.714
gonad development GO:0008406 141 0.712
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.712
positive regulation of cell motility GO:2000147 116 0.712
Human
response to dexamethasone GO:0071548 8 0.705
Mouse Rat
positive regulation of myeloid cell differentiation GO:0045639 43 0.705
actin filament organization GO:0007015 113 0.701
cellular response to interferon gamma GO:0071346 25 0.699
regulation of calcium ion transport GO:0051924 69 0.699
Rat
dna metabolic process GO:0006259 303 0.697
Human
pigmentation GO:0043473 71 0.697
multicellular organism growth GO:0035264 161 0.695
development of primary sexual characteristics GO:0045137 143 0.695
response to radiation GO:0009314 165 0.694
Rat
monocyte differentiation GO:0030224 9 0.693
epithelial tube morphogenesis GO:0060562 303 0.693
endochondral bone morphogenesis GO:0060350 50 0.692
female gamete generation GO:0007292 74 0.691
endothelial cell differentiation GO:0045446 41 0.690
response to acid chemical GO:0001101 111 0.687
renin angiotensin regulation of aldosterone production GO:0002018 3 0.684
morphogenesis of a branching structure GO:0001763 203 0.679
immune response regulating signaling pathway GO:0002764 125 0.677
response to light stimulus GO:0009416 135 0.672
regulation of histone acetylation GO:0035065 19 0.670
defense response to other organism GO:0098542 197 0.669
Rat Worm
cation homeostasis GO:0055080 212 0.666
response to organonitrogen compound GO:0010243 246 0.653
positive regulation of activated t cell proliferation GO:0042104 8 0.648
organelle assembly GO:0070925 177 0.645
skin development GO:0043588 220 0.644
Mouse
intracellular receptor signaling pathway GO:0030522 74 0.643
limb development GO:0060173 166 0.639
negative regulation of immune system process GO:0002683 209 0.635
jak stat cascade involved in growth hormone signaling pathway GO:0060397 4 0.633
blood vessel morphogenesis GO:0048514 285 0.631
cellular ketone metabolic process GO:0042180 84 0.631
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.631
bone development GO:0060348 120 0.628
Rat
regulation of glutamine family amino acid metabolic process GO:0000820 1 0.626
mammary gland morphogenesis GO:0060443 54 0.622
germ cell development GO:0007281 185 0.622
negative regulation of neurotransmitter transport GO:0051589 7 0.621
cellular response to abiotic stimulus GO:0071214 56 0.621
inositol lipid mediated signaling GO:0048017 41 0.621
positive regulation of lipid metabolic process GO:0045834 40 0.620
Human
regulation of protein kinase activity GO:0045859 232 0.616
Human
luteinization GO:0001553 8 0.613
carbohydrate biosynthetic process GO:0016051 74 0.611
Human
immune response activating signal transduction GO:0002757 116 0.610
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.610
myeloid leukocyte activation GO:0002274 83 0.608
regulation of smooth muscle cell migration GO:0014910 6 0.606
rho protein signal transduction GO:0007266 32 0.602
hair follicle development GO:0001942 85 0.600
Mouse
cellular response to glucocorticoid stimulus GO:0071385 13 0.600
Mouse Rat
regulation of cytokine production GO:0001817 266 0.600
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.599
response to decreased oxygen levels GO:0036293 59 0.597
Rat
sensory perception GO:0007600 245 0.593
regulation of hormone levels GO:0010817 211 0.592
Fly
regulation of renal output by angiotensin GO:0002019 2 0.591
alpha amino acid metabolic process GO:1901605 59 0.591
striated muscle tissue development GO:0014706 293 0.585
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.580
ammonia assimilation cycle GO:0019676 2 0.578
cellular response to steroid hormone stimulus GO:0071383 33 0.576
Mouse Rat
gliogenesis GO:0042063 141 0.576
muscle cell development GO:0055001 133 0.575
Human
modification of morphology or physiology of other organism GO:0035821 18 0.568
Human
cellular divalent inorganic cation homeostasis GO:0072503 127 0.566
multicellular organismal homeostasis GO:0048871 164 0.564
hexose biosynthetic process GO:0019319 39 0.563
myeloid cell differentiation GO:0030099 233 0.555
regulation of leukocyte apoptotic process GO:2000106 56 0.554
Mouse
myeloid cell homeostasis GO:0002262 114 0.550
positive regulation of chromosome organization GO:2001252 33 0.548
g protein coupled receptor signaling pathway GO:0007186 243 0.547
appendage development GO:0048736 166 0.546
response to inorganic substance GO:0010035 96 0.545
smooth muscle cell migration GO:0014909 10 0.544
regulation of leukocyte proliferation GO:0070663 121 0.541
cellular response to corticosteroid stimulus GO:0071384 13 0.536
Mouse Rat
organic hydroxy compound biosynthetic process GO:1901617 77 0.532
Mouse
b cell activation GO:0042113 161 0.532
Human
regulation of jak stat cascade GO:0046425 34 0.530
eye photoreceptor cell differentiation GO:0001754 41 0.530
protein catabolic process GO:0030163 221 0.528
response to drug GO:0042493 75 0.528
Rat
positive regulation of neuron apoptotic process GO:0043525 25 0.528
positive regulation of histone acetylation GO:0035066 8 0.528
response to extracellular stimulus GO:0009991 127 0.526
Rat
positive regulation of epithelial cell proliferation GO:0050679 68 0.524
Rat
cd4 positive alpha beta t cell activation GO:0035710 45 0.524
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.523
dendritic cell cytokine production GO:0002371 3 0.523
regulation of tissue remodeling GO:0034103 38 0.521
tor signaling GO:0031929 21 0.520
maintenance of location GO:0051235 89 0.515
cell growth involved in cardiac muscle cell development GO:0061049 3 0.510
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.506
positive regulation of jak stat cascade GO:0046427 22 0.505
cellular homeostasis GO:0019725 240 0.503
response to corticosteroid GO:0031960 20 0.500
Mouse Rat
cardiac muscle cell differentiation GO:0055007 69 0.499
cell fate commitment GO:0045165 210 0.497
Mouse
response to bile acid GO:1903412 1 0.494
bone morphogenesis GO:0060349 78 0.488
Rat
response to peptide hormone GO:0043434 127 0.488
myofibril assembly GO:0030239 34 0.487
female sex differentiation GO:0046660 84 0.487
wound healing GO:0042060 157 0.485
Rat
odontogenesis GO:0042476 78 0.482
epithelial cell development GO:0002064 159 0.482
positive regulation of cell adhesion GO:0045785 80 0.481
cellular response to hormone stimulus GO:0032870 150 0.479
Mouse Rat
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.478
calcium mediated signaling GO:0019722 46 0.478
positive regulation of b cell activation GO:0050871 49 0.477
Human
regulation of cholesterol esterification GO:0010872 2 0.475
positive regulation of mammary gland involution GO:1903521 4 0.472
cellular response to radiation GO:0071478 28 0.472
keratinocyte migration GO:0051546 3 0.472
regulation of system process GO:0044057 200 0.470
leukocyte activation involved in immune response GO:0002366 126 0.470
Human
b cell proliferation GO:0042100 53 0.467
cellular response to cytokine stimulus GO:0071345 189 0.467
response to lithium ion GO:0010226 10 0.465
regulation of mammary gland involution GO:1903519 4 0.462
immature b cell differentiation GO:0002327 10 0.456
negative regulation of myeloid cell differentiation GO:0045638 38 0.454
hormone metabolic process GO:0042445 86 0.454
cellular response to amino acid stimulus GO:0071230 29 0.452
cellular amide metabolic process GO:0043603 58 0.451
regulation of angiogenesis GO:0045765 81 0.450
glial cell differentiation GO:0010001 131 0.450
gluconeogenesis GO:0006094 39 0.449
genetic imprinting GO:0071514 27 0.448
macromolecule catabolic process GO:0009057 281 0.448
Human
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.448
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.447
embryonic skeletal system development GO:0048706 120 0.447
embryonic appendage morphogenesis GO:0035113 126 0.446
positive regulation of fibroblast proliferation GO:0048146 20 0.446
regulation of hydrolase activity GO:0051336 246 0.446
antigen receptor mediated signaling pathway GO:0050851 64 0.442
response to interferon gamma GO:0034341 34 0.441
fatty acid beta oxidation GO:0006635 16 0.440
response to corticosterone GO:0051412 1 0.439
angiogenesis GO:0001525 201 0.438
granulocyte migration GO:0097530 43 0.438
cellular ion homeostasis GO:0006873 165 0.435
regulation of protein targeting GO:1903533 61 0.433
cell migration involved in coronary angiogenesis GO:0060981 1 0.432
regulation of vitamin metabolic process GO:0030656 3 0.431
internal protein amino acid acetylation GO:0006475 42 0.427
embryonic skeletal system morphogenesis GO:0048704 91 0.425
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.423
regulation of fibroblast proliferation GO:0048145 34 0.421
sensory perception of chemical stimulus GO:0007606 51 0.419
regulation of transferase activity GO:0051338 263 0.419
Human
cellular response to x ray GO:0071481 2 0.418
positive regulation of peptidase activity GO:0010952 49 0.418
lymphocyte homeostasis GO:0002260 64 0.418
regulation of osteoblast differentiation GO:0045667 67 0.417
regulation of lymphocyte differentiation GO:0045619 107 0.417
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.416
fat soluble vitamin metabolic process GO:0006775 11 0.415
energy derivation by oxidation of organic compounds GO:0015980 77 0.415
ribonucleotide biosynthetic process GO:0009260 59 0.414
Human
angiogenesis involved in coronary vascular morphogenesis GO:0060978 2 0.410
glucocorticoid biosynthetic process GO:0006704 5 0.409
response to insulin GO:0032868 100 0.406
calcium ion homeostasis GO:0055074 127 0.404
regulation of peptidyl serine phosphorylation GO:0033135 39 0.402
Human
retinal cone cell development GO:0046549 8 0.401
inflammatory response GO:0006954 244 0.399
appendage morphogenesis GO:0035107 149 0.398
cation transport GO:0006812 399 0.397
metanephric mesenchymal cell migration GO:0035789 2 0.394
response to peptide GO:1901652 136 0.393
signal transduction in absence of ligand GO:0038034 55 0.393
Mouse
regulation of cell motility GO:2000145 236 0.393
Human
forebrain development GO:0030900 302 0.387
regulation of steroid metabolic process GO:0019218 39 0.386
osteoclast differentiation GO:0030316 62 0.386
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.385
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.385
regulation of b cell activation GO:0050864 81 0.379
Human
body morphogenesis GO:0010171 45 0.379
regulation of mitotic cell cycle GO:0007346 126 0.378
Human Rat
carbohydrate metabolic process GO:0005975 230 0.370
Human
melanocyte differentiation GO:0030318 25 0.370
regulation of chromatin modification GO:1903308 57 0.368
positive regulation of rac gtpase activity GO:0032855 14 0.365
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.365
negative regulation of phosphorylation GO:0042326 166 0.362
Human
regulation of t cell differentiation GO:0045580 83 0.361
b cell differentiation GO:0030183 78 0.360
leukocyte chemotaxis GO:0030595 69 0.360
regulation of mast cell apoptotic process GO:0033025 5 0.354
digestion GO:0007586 40 0.352
pallium development GO:0021543 120 0.352
cholesterol esterification GO:0034435 3 0.351
ovarian follicle development GO:0001541 40 0.351
regulation of inflammatory response GO:0050727 147 0.350
regulation of blood pressure GO:0008217 93 0.350
metal ion homeostasis GO:0055065 189 0.349
monosaccharide biosynthetic process GO:0046364 44 0.349
regulation of urea metabolic process GO:0034255 1 0.348
succinate metabolic process GO:0006105 4 0.347
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 10 0.343
tyrosine phosphorylation of stat protein GO:0007260 23 0.343
positive regulation of dephosphorylation GO:0035306 6 0.341
Human
megakaryocyte differentiation GO:0030219 26 0.341
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.340
regulation of vasculature development GO:1901342 88 0.340
negative regulation of cytokine production GO:0001818 84 0.337
Human
positive regulation of osteoblast differentiation GO:0045669 34 0.337
mitotic cell cycle GO:0000278 195 0.335
Human Rat
cardiocyte differentiation GO:0035051 87 0.335
positive regulation of apoptotic process involved in morphogenesis GO:1902339 4 0.335
cellular metal ion homeostasis GO:0006875 151 0.334
neutrophil chemotaxis GO:0030593 36 0.333
respiratory tube development GO:0030323 167 0.331
mammary gland duct morphogenesis GO:0060603 38 0.331
cellular response to tumor necrosis factor GO:0071356 21 0.330
taurine metabolic process GO:0019530 4 0.329
regulation of cell adhesion GO:0030155 154 0.328
Human
positive regulation of peptidyl lysine acetylation GO:2000758 9 0.326
single organismal cell cell adhesion GO:0016337 131 0.324
Human
regulation of protein localization GO:0032880 231 0.323
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.323
cellular response to biotic stimulus GO:0071216 92 0.323
Human
response to growth factor GO:0070848 198 0.322
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.319
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 3 0.319
liver development GO:0001889 66 0.318
sensory perception of smell GO:0007608 26 0.318
regulation of monooxygenase activity GO:0032768 7 0.317
response to hypoxia GO:0001666 58 0.316
Rat
signal transduction by p53 class mediator GO:0072331 51 0.316
regulation of antimicrobial humoral response GO:0002759 3 0.315
response to oxygen levels GO:0070482 62 0.315
Rat
response to steroid hormone GO:0048545 56 0.313
Human Mouse Rat
male sex differentiation GO:0046661 109 0.312
response to inactivity GO:0014854 4 0.309
positive regulation of protein acetylation GO:1901985 9 0.309
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.308
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.308
response to nutrient levels GO:0031667 109 0.308
Rat
vitamin metabolic process GO:0006766 23 0.304
carbohydrate derivative catabolic process GO:1901136 231 0.303
Human
creatinine metabolic process GO:0046449 3 0.303
regulation of cell activation GO:0050865 289 0.302
tissue migration GO:0090130 68 0.301
Human
regulation of cell substrate adhesion GO:0010810 73 0.300
cellular response to lipopolysaccharide GO:0071222 77 0.299
Human
multi multicellular organism process GO:0044706 109 0.298
Rat
fatty acid metabolic process GO:0006631 121 0.297
regulation of ammonia assimilation cycle GO:2001248 1 0.297
phosphatidylinositol mediated signaling GO:0048015 41 0.294
ossification GO:0001503 216 0.294
actin cytoskeleton organization GO:0030036 220 0.294
regulation of natural killer cell differentiation GO:0032823 11 0.293
glycolipid metabolic process GO:0006664 25 0.293
long chain fatty acid transport GO:0015909 15 0.292
hematopoietic progenitor cell differentiation GO:0002244 143 0.291
Human
response to molecule of bacterial origin GO:0002237 143 0.291
Human
negative regulation of homeostatic process GO:0032845 71 0.290
Rat
body fluid secretion GO:0007589 53 0.288
t cell proliferation GO:0042098 120 0.286
induction by organism of immune response of other organism involved in symbiotic interaction GO:0052558 1 0.285
endothelial cell migration GO:0043542 44 0.284
Human
cellular response to acid chemical GO:0071229 68 0.283
regulation of steroid biosynthetic process GO:0050810 26 0.283
t cell differentiation in thymus GO:0033077 77 0.283
cellular response to external stimulus GO:0071496 88 0.283
negative regulation of t cell activation GO:0050868 65 0.282
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.281
syncytium formation by plasma membrane fusion GO:0000768 42 0.277
neutrophil migration GO:1990266 37 0.277
mast cell differentiation GO:0060374 5 0.277
positive regulation of cholesterol esterification GO:0010873 1 0.277
regulation of hair follicle cell proliferation GO:0071336 2 0.274
cardiac muscle tissue development GO:0048738 130 0.273
hair cycle GO:0042633 90 0.272
Mouse
positive regulation of organelle organization GO:0010638 128 0.270
regulation of rho gtpase activity GO:0032319 58 0.269
erk1 and erk2 cascade GO:0070371 77 0.267
pro t cell differentiation GO:0002572 3 0.266
regulation of proteolysis GO:0030162 164 0.266
nucleoside metabolic process GO:0009116 246 0.266
Human
actomyosin structure organization GO:0031032 56 0.265
regulation of nitric oxide synthase activity GO:0050999 6 0.265
eye photoreceptor cell development GO:0042462 31 0.264
regulation of mapk cascade GO:0043408 248 0.264
Human
skeletal system morphogenesis GO:0048705 203 0.262
Mouse Rat
regulation of muscle adaptation GO:0043502 31 0.262
liposaccharide metabolic process GO:1903509 27 0.261
cell type specific apoptotic process GO:0097285 268 0.259
Mouse
response to ketone GO:1901654 15 0.258
Human Mouse Rat
cellular response to metal ion GO:0071248 31 0.258
glycerophospholipid metabolic process GO:0006650 71 0.257
Human
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.257
mitotic spindle organization GO:0007052 10 0.256
vitamin biosynthetic process GO:0009110 7 0.254
peptide metabolic process GO:0006518 46 0.254
dna biosynthetic process GO:0071897 22 0.253
cellular response to insulin stimulus GO:0032869 78 0.249
tissue homeostasis GO:0001894 115 0.249
cellular chemical homeostasis GO:0055082 215 0.248
posttranscriptional regulation of gene expression GO:0010608 155 0.247
regulation of ras gtpase activity GO:0032318 88 0.247
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.246
Rat
neuron apoptotic process GO:0051402 142 0.245
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.244
Human
dicarboxylic acid metabolic process GO:0043648 18 0.243
positive regulation of t cell activation GO:0050870 101 0.243
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.242
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.242
polysaccharide metabolic process GO:0005976 39 0.241
Human
nephron development GO:0072006 109 0.237
Rat
regulation of response to wounding GO:1903034 189 0.235
generation of precursor metabolites and energy GO:0006091 103 0.234
actin filament bundle assembly GO:0051017 40 0.233
regulation of organ morphogenesis GO:2000027 144 0.232
epithelium migration GO:0090132 63 0.231
Human
regionalization GO:0003002 337 0.230
Mouse
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 15 0.229
neuron projection guidance GO:0097485 141 0.229
Mouse Fly
peptidyl lysine modification GO:0018205 77 0.229
regulation of adrenergic receptor signaling pathway GO:0071877 4 0.228
eating behavior GO:0042755 15 0.228
Worm
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.227
cellular carbohydrate metabolic process GO:0044262 119 0.227

Tgfb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.969
Human
musculoskeletal system disease DOID:17 0 0.969
Human
connective tissue disease DOID:65 0 0.969
Human
disease of cellular proliferation DOID:14566 0 0.644
cancer DOID:162 0 0.484
organ system cancer DOID:0050686 0 0.484
hypertension DOID:10763 0 0.458
artery disease DOID:0050828 0 0.458
vascular disease DOID:178 0 0.458
essential hypertension DOID:10825 0 0.458
cardiovascular system disease DOID:1287 0 0.458
immune system cancer DOID:0060083 0 0.444
hematologic cancer DOID:2531 0 0.444
bone remodeling disease DOID:0080005 0 0.296
Human
bone disease DOID:0080001 0 0.296
Human
disease of metabolism DOID:0014667 0 0.268