Mus musculus

209 known processes

Tgfb2

transforming growth factor, beta 2

(Aliases: Tgf-beta2,Tgfb-2,BB105277)

Tgfb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
stem cell development GO:0048864 219 1.000
Human Mouse
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 1.000
stem cell differentiation GO:0048863 268 1.000
Human Mouse
embryonic organ morphogenesis GO:0048562 276 1.000
Rat
axon guidance GO:0007411 141 1.000
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 1.000
mesenchyme development GO:0060485 152 1.000
Human Mouse
cardioblast migration to the midline involved in heart field formation GO:0060975 1 1.000
pyramidal neuron migration GO:0021852 1 1.000
heart morphogenesis GO:0003007 178 1.000
Human
epithelial tube morphogenesis GO:0060562 303 1.000
Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 1.000
Fly
embryonic skeletal system development GO:0048706 120 1.000
Rat
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 1.000
clara cell differentiation GO:0060486 4 1.000
cardioblast migration GO:0003260 1 1.000
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 1.000
trachea formation GO:0060440 3 1.000
neuron projection guidance GO:0097485 141 1.000
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 1.000
epithelial to mesenchymal transition GO:0001837 47 1.000
Human Mouse
mesenchymal cell differentiation GO:0048762 107 1.000
Human Mouse
mitral valve morphogenesis GO:0003183 4 1.000
mesenchymal cell development GO:0014031 93 1.000
Human Mouse
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 1.000
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 1.000
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.999
metanephric capsule specification GO:0072267 1 0.999
activation of mapk activity involved in innate immune response GO:0035419 2 0.999
embryonic heart tube anterior posterior pattern specification GO:0035054 3 0.999
embryonic skeletal system morphogenesis GO:0048704 91 0.999
Rat
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.999
appendage morphogenesis GO:0035107 149 0.999
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.999
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.999
positive regulation of transcription by glucose GO:0046016 3 0.999
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.999
auditory receptor cell fate determination GO:0042668 3 0.999
chondrocyte development GO:0002063 24 0.999
negative regulation of transcription by glucose GO:0045014 1 0.998
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.998
positive regulation of bmp signaling pathway GO:0030513 23 0.998
extracellular matrix dependent thymocyte migration GO:0072680 1 0.998
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.998
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.998
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.998
heart field specification GO:0003128 6 0.998
ventricular septum morphogenesis GO:0060412 27 0.998
striated muscle tissue development GO:0014706 293 0.998
Human Mouse Rat
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.998
axonogenesis GO:0007409 274 0.998
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.998
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.998
Fly
cell proliferation in hindbrain GO:0021534 10 0.997
skeletal system development GO:0001501 356 0.997
telencephalon development GO:0021537 186 0.997
cell migration to the midline involved in heart development GO:0003318 1 0.997
atrial septum primum morphogenesis GO:0003289 3 0.997
embryonic heart tube formation GO:0003144 1 0.997
positive regulation of thymocyte migration GO:2000412 2 0.997
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.997
ossification GO:0001503 216 0.997
Human Mouse
bmp signaling pathway GO:0030509 93 0.997
endocardial cushion formation GO:0003272 13 0.997
otolith morphogenesis GO:0032474 3 0.996
regionalization GO:0003002 337 0.996
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.996
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.996
cardiac epithelial to mesenchymal transition GO:0060317 18 0.996
Human
carbon catabolite repression of transcription GO:0045013 1 0.996
mitral valve development GO:0003174 4 0.996
locus ceruleus development GO:0021703 1 0.996
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.996
regulation of epithelial to mesenchymal transition GO:0010717 22 0.996
Human Mouse
chemotaxis GO:0006935 247 0.996
closure of optic fissure GO:0061386 2 0.995
regulation of astrocyte differentiation GO:0048710 20 0.995
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.995
regulation of vascular wound healing GO:0061043 2 0.995
eosinophil migration GO:0072677 3 0.995
positive regulation of odontogenesis GO:0042482 4 0.995
Mouse
bone morphogenesis GO:0060349 78 0.995
Rat
septum primum development GO:0003284 4 0.994
lateral mesoderm morphogenesis GO:0048369 3 0.994
gastrulation GO:0007369 116 0.994
regulation of cardiac muscle tissue development GO:0055024 31 0.994
limb morphogenesis GO:0035108 149 0.994
ear morphogenesis GO:0042471 118 0.993
hindbrain tangential cell migration GO:0021934 2 0.993
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.993
embryonic heart tube development GO:0035050 65 0.993
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.993
growth plate cartilage chondrocyte development GO:0003431 3 0.993
cartilage development GO:0051216 140 0.993
retinal ganglion cell axon guidance GO:0031290 18 0.992
heart valve morphogenesis GO:0003179 21 0.992
embryonic heart tube morphogenesis GO:0003143 51 0.992
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.992
Human Mouse Fly
positive regulation of map kinase activity GO:0043406 84 0.992
skeletal muscle organ development GO:0060538 163 0.992
Rat
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.992
cell aggregation GO:0098743 18 0.991
regulation of bmp signaling pathway GO:0030510 60 0.991
lung development GO:0030324 164 0.991
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.991
atrial ventricular junction remodeling GO:0003294 2 0.991
primary neural tube formation GO:0014020 95 0.991
noradrenergic neuron differentiation GO:0003357 6 0.991
chondrocyte differentiation GO:0002062 72 0.991
positive regulation of axon extension GO:0045773 20 0.990
embryonic appendage morphogenesis GO:0035113 126 0.990
negative regulation of gastrulation GO:2000542 3 0.990
cardiac muscle tissue development GO:0048738 130 0.990
Human
lateral mesoderm formation GO:0048370 3 0.989
regulation of endodermal cell differentiation GO:1903224 2 0.989
endocardial cushion to mesenchymal transition GO:0090500 5 0.989
endodermal cell fate commitment GO:0001711 12 0.988
positive regulation of ossification GO:0045778 47 0.988
Human
positive regulation of transcription via serum response element binding GO:0010735 1 0.988
growth plate cartilage development GO:0003417 14 0.987
response to growth factor GO:0070848 198 0.987
Human Mouse Fly
renal capsule specification GO:0072130 1 0.987
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.986
cardiac chamber morphogenesis GO:0003206 93 0.986
neural tube closure GO:0001843 90 0.986
negative regulation of cell proliferation GO:0008285 296 0.986
Human Mouse Rat
blood vessel morphogenesis GO:0048514 285 0.985
cardiac right ventricle formation GO:0003219 3 0.985
regulation of muscle tissue development GO:1901861 97 0.984
Mouse
somitogenesis GO:0001756 69 0.984
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.984
cardiac atrium development GO:0003230 24 0.984
branching involved in ureteric bud morphogenesis GO:0001658 56 0.984
vascular wound healing GO:0061042 3 0.984
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.984
mesonephric epithelium development GO:0072163 94 0.984
Mouse
positive regulation of glial cell differentiation GO:0045687 21 0.983
skeletal system morphogenesis GO:0048705 203 0.983
positive regulation of stem cell proliferation GO:2000648 59 0.983
regulation of glial cell differentiation GO:0045685 41 0.982
embryonic heart tube left right pattern formation GO:0060971 5 0.981
stem cell maintenance GO:0019827 130 0.981
ventricular cardiac muscle cell differentiation GO:0055012 17 0.980
epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198 10 0.979
regulation of endodermal cell fate specification GO:0042663 2 0.979
forebrain generation of neurons GO:0021872 63 0.979
mesenchymal cell proliferation involved in ureteric bud development GO:0072138 3 0.979
negative regulation of endodermal cell differentiation GO:1903225 1 0.978
bmp signaling pathway involved in heart development GO:0061312 2 0.978
morphogenesis of a branching epithelium GO:0061138 193 0.978
Mouse
regulation of hepatocyte differentiation GO:0070366 2 0.977
forebrain neuron differentiation GO:0021879 52 0.977
negative regulation of epithelial cell proliferation GO:0050680 64 0.977
Human
positive regulation of osteoblast differentiation GO:0045669 34 0.976
cardiac septum morphogenesis GO:0060411 46 0.975
camera type eye development GO:0043010 266 0.975
Mouse
endochondral bone morphogenesis GO:0060350 50 0.974
epithelial cell development GO:0002064 159 0.974
nephron tubule morphogenesis GO:0072078 68 0.974
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.974
salivary gland morphogenesis GO:0007435 33 0.973
Human
cell adhesion GO:0007155 329 0.973
Human
globus pallidus development GO:0021759 2 0.973
secondary heart field specification GO:0003139 6 0.972
ear development GO:0043583 200 0.971
Rat
ureteric bud development GO:0001657 94 0.971
Mouse
cardiac chamber development GO:0003205 108 0.970
gliogenesis GO:0042063 141 0.970
Human
regulation of heart morphogenesis GO:2000826 22 0.970
digestive tract development GO:0048565 190 0.970
Human Rat
axial mesodermal cell fate commitment GO:0048322 1 0.969
regulation of map kinase activity GO:0043405 120 0.969
axonogenesis involved in innervation GO:0060385 5 0.968
rac protein signal transduction GO:0016601 13 0.968
negative regulation of neuron projection development GO:0010977 50 0.967
positive regulation of apoptotic process GO:0043065 217 0.967
positive regulation of ureteric bud formation GO:0072107 3 0.966
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.966
carbon catabolite activation of transcription GO:0045991 4 0.966
heart valve development GO:0003170 23 0.966
ascending aorta morphogenesis GO:0035910 3 0.963
formation of radial glial scaffolds GO:0021943 4 0.963
positive regulation of nervous system development GO:0051962 221 0.963
ventricular zone neuroblast division GO:0021847 3 0.962
cardiac septum development GO:0003279 59 0.961
prostate gland stromal morphogenesis GO:0060741 2 0.960
regulation of cell migration GO:0030334 219 0.960
Human Rat
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.960
neural crest cell differentiation GO:0014033 54 0.960
mesonephric tubule development GO:0072164 94 0.959
Mouse
myelination in peripheral nervous system GO:0022011 19 0.959
endothelial cell fate commitment GO:0060839 2 0.959
pallium development GO:0021543 120 0.959
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.959
sensory organ morphogenesis GO:0090596 242 0.958
Mouse
positive regulation of cell migration GO:0030335 109 0.958
Human Rat
inner cell mass cellular morphogenesis GO:0001828 1 0.958
exocrine system development GO:0035272 45 0.957
Human
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.956
digestive system development GO:0055123 200 0.955
Human Rat
leukocyte differentiation GO:0002521 342 0.955
Mouse
cardiac muscle cell development GO:0055013 39 0.954
anterior commissure morphogenesis GO:0021960 6 0.954
central nervous system projection neuron axonogenesis GO:0021952 21 0.953
ventricular cardiac myofibril assembly GO:0055005 3 0.953
branching morphogenesis of an epithelial tube GO:0048754 159 0.953
Mouse
growth plate cartilage chondrocyte growth GO:0003430 2 0.952
regulation of leukocyte differentiation GO:1902105 159 0.952
lateral mesodermal cell differentiation GO:0048371 3 0.952
atrioventricular valve morphogenesis GO:0003181 13 0.952
positive regulation of vascular wound healing GO:0035470 1 0.951
astrocyte fate commitment GO:0060018 4 0.951
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.950
limb development GO:0060173 166 0.949
mesenchymal cell proliferation GO:0010463 44 0.949
regulation of hormone secretion GO:0046883 88 0.949
Fly
myelination GO:0042552 74 0.949
glomerular mesangial cell development GO:0072144 3 0.949
cardiogenic plate morphogenesis GO:0003142 1 0.948
sinoatrial node cell differentiation GO:0060921 3 0.946
epidermis development GO:0008544 187 0.946
tendon formation GO:0035992 4 0.946
single organismal cell cell adhesion GO:0016337 131 0.945
nephron morphogenesis GO:0072028 69 0.945
atrial septum development GO:0003283 12 0.944
embryonic viscerocranium morphogenesis GO:0048703 8 0.944
fibronectin dependent thymocyte migration GO:0072681 1 0.944
regulation of cartilage development GO:0061035 44 0.943
cardiac muscle cell differentiation GO:0055007 69 0.943
regulation of osteoblast differentiation GO:0045667 67 0.942
neuron projection extension GO:1990138 64 0.941
negative regulation of bmp signaling pathway GO:0030514 35 0.941
determination of heart left right asymmetry GO:0061371 48 0.941
endodermal cell fate specification GO:0001714 4 0.941
cardiac endothelial cell differentiation GO:0003348 4 0.940
regulation of mapk cascade GO:0043408 248 0.940
Human
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.939
renal system development GO:0072001 225 0.938
Mouse Rat
aorta morphogenesis GO:0035909 22 0.938
regulation of gliogenesis GO:0014013 50 0.938
negative regulation of endodermal cell fate specification GO:0042664 1 0.938
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.937
digestive tract morphogenesis GO:0048546 147 0.937
inner ear morphogenesis GO:0042472 101 0.937
regulation of neuron differentiation GO:0045664 281 0.936
myofibril assembly GO:0030239 34 0.935
bmp signaling pathway involved in mesodermal cell fate specification GO:0060803 1 0.935
chondrocyte hypertrophy GO:0003415 4 0.935
negative regulation of chondrocyte differentiation GO:0032331 13 0.935
respiratory system development GO:0060541 190 0.934
regulation of homeostatic process GO:0032844 182 0.934
regulation of neuron projection development GO:0010975 169 0.934
fused antrum stage GO:0048165 1 0.933
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 5 0.932
negative regulation of immature t cell proliferation GO:0033087 3 0.932
embryonic nail plate morphogenesis GO:0035880 3 0.932
glomerular mesangial cell differentiation GO:0072008 3 0.932
lung induction GO:0060492 3 0.932
cardiocyte differentiation GO:0035051 87 0.930
Human
tendon cell differentiation GO:0035990 4 0.928
formation of primary germ layer GO:0001704 77 0.928
endocardial cell differentiation GO:0060956 4 0.927
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.927
glycoprotein metabolic process GO:0009100 116 0.927
angiogenesis GO:0001525 201 0.927
cardiac atrium morphogenesis GO:0003209 23 0.926
hormone secretion GO:0046879 128 0.926
Fly
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.924
mesonephros development GO:0001823 97 0.924
Mouse
prostate gland morphogenesis GO:0060512 32 0.923
regulation of ossification GO:0030278 112 0.922
Human Mouse
neural crest cell development GO:0014032 48 0.921
positive regulation of kinase activity GO:0033674 155 0.921
Human
rhythmic process GO:0048511 174 0.921
labyrinthine layer morphogenesis GO:0060713 21 0.919
pancreatic pp cell fate commitment GO:0003329 2 0.919
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.919
urogenital system development GO:0001655 261 0.919
Mouse Rat
respiratory tube development GO:0030323 167 0.919
cell proliferation in midbrain GO:0033278 2 0.917
positive regulation of cell motility GO:2000147 116 0.915
Human Rat
regulation of organ morphogenesis GO:2000027 144 0.914
Mouse
activation of mapk activity GO:0000187 59 0.913
transcriptional activation by promoter enhancer looping GO:0071733 2 0.912
protein import into nucleus GO:0006606 95 0.911
Human Mouse
cranial suture morphogenesis GO:0060363 8 0.911
Rat
muscle tissue development GO:0060537 308 0.910
Human Mouse Rat
cardiac ventricle development GO:0003231 83 0.910
osteoblast development GO:0002076 17 0.908
regulation of protein serine threonine kinase activity GO:0071900 157 0.906
cerebral cortex cell migration GO:0021795 44 0.906
dichotomous subdivision of terminal units involved in ureteric bud branching GO:0060678 1 0.905
primary prostatic bud elongation GO:0060516 2 0.903
glial cell differentiation GO:0010001 131 0.903
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.902
neural crest cell migration GO:0001755 32 0.902
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.901
positive regulation of heart growth GO:0060421 18 0.901
metanephric nephron tubule formation GO:0072289 4 0.901
positive regulation of programmed cell death GO:0043068 218 0.900
detection of stimulus GO:0051606 84 0.899
heart trabecula formation GO:0060347 14 0.899
positive regulation of epithelial to mesenchymal transition GO:0010718 13 0.899
Human Mouse
germ cell development GO:0007281 185 0.899
positive regulation of transferase activity GO:0051347 167 0.899
Human
regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation GO:2000702 1 0.897
regulation of mesodermal cell fate specification GO:0042661 5 0.897
regulation of cellular ketone metabolic process GO:0010565 66 0.897
regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000307 1 0.896
cell proliferation involved in mesonephros development GO:0061209 4 0.895
glomerulus vasculature morphogenesis GO:0072103 6 0.895
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.895
hindbrain development GO:0030902 128 0.895
Rat
bone mineralization GO:0030282 54 0.894
regulation of kinase activity GO:0043549 249 0.893
Human
smoothened signaling pathway GO:0007224 105 0.890
regulation of protein kinase activity GO:0045859 232 0.890
Human
regulation of ureteric bud formation GO:0072106 3 0.889
epithelial cell differentiation involved in kidney development GO:0035850 23 0.889
axon extension involved in axon guidance GO:0048846 14 0.888
positive regulation of mapk cascade GO:0043410 170 0.888
Human
regulation of cytokine production GO:0001817 266 0.887
Human Mouse
regulation of mesenchymal cell proliferation GO:0010464 37 0.887
glycosaminoglycan metabolic process GO:0030203 34 0.886
regulation of cell cycle GO:0051726 281 0.886
cellular ketone metabolic process GO:0042180 84 0.886
regulation of cell activation GO:0050865 289 0.886
Mouse
negative regulation of cell fate specification GO:0009996 4 0.884
regulation of cardioblast differentiation GO:0051890 3 0.884
Human
negative regulation of astrocyte differentiation GO:0048712 10 0.883
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.881
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.880
metanephric capsule formation GO:0072266 1 0.879
oocyte axis specification GO:0007309 2 0.878
carbon catabolite regulation of transcription GO:0045990 4 0.877
regulation of secretion GO:0051046 274 0.876
Human Fly
retina vasculature development in camera type eye GO:0061298 17 0.875
positive regulation of transcription from rna polymerase iii promoter GO:0045945 1 0.875
tube formation GO:0035148 140 0.875
cell migration involved in heart formation GO:0060974 1 0.873
bone development GO:0060348 120 0.873
Rat
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.872
positive regulation of cell development GO:0010720 237 0.872
Human Mouse
cardiac cell fate determination GO:0060913 2 0.871
embryonic neurocranium morphogenesis GO:0048702 3 0.871
Rat
branch elongation involved in ureteric bud branching GO:0060681 3 0.870
neuron migration GO:0001764 122 0.869
regulation of intracellular transport GO:0032386 159 0.868
Mouse Rat
synaptic transmission GO:0007268 329 0.868
negative regulation of molecular function GO:0044092 258 0.867
Human
hair cycle GO:0042633 90 0.866
regulation of t cell proliferation GO:0042129 92 0.864
Mouse
foramen ovale closure GO:0035922 1 0.864
positive regulation of protein phosphorylation GO:0001934 242 0.864
Human
olfactory bulb interneuron differentiation GO:0021889 12 0.864
embryonic skeletal joint morphogenesis GO:0060272 11 0.863
muscular septum morphogenesis GO:0003150 4 0.863
commissural neuron axon guidance GO:0071679 8 0.863
endocardial cushion morphogenesis GO:0003203 18 0.863
mesonephric tubule morphogenesis GO:0072171 63 0.862
ovarian cumulus expansion GO:0001550 1 0.862
metanephric comma shaped body morphogenesis GO:0072278 1 0.862
negative regulation of mesodermal cell fate specification GO:0042662 3 0.862
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.862
regulation of auditory receptor cell differentiation GO:0045607 4 0.861
cardiac muscle fiber development GO:0048739 4 0.861
mesoderm development GO:0007498 100 0.858
cellular homeostasis GO:0019725 240 0.856
Mouse Rat
regulation of cardiac muscle cell differentiation GO:2000725 9 0.855
atrial septum morphogenesis GO:0060413 11 0.855
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.855
Human Mouse Fly
coronary vasculature development GO:0060976 12 0.855
hypophysis morphogenesis GO:0048850 3 0.854
regulation of eosinophil migration GO:2000416 2 0.854
positive regulation of bone mineralization GO:0030501 12 0.853
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.852
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.852
Human Mouse
mapk cascade GO:0000165 281 0.851
Human
regulation of binding GO:0051098 111 0.849
Mouse
mesoderm morphogenesis GO:0048332 64 0.848
proteoglycan metabolic process GO:0006029 38 0.848
kidney development GO:0001822 213 0.847
Mouse Rat
glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000701 1 0.846
neural crest cell fate commitment GO:0014034 1 0.846
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.846
t cell differentiation in thymus GO:0033077 77 0.845
cellular amino acid metabolic process GO:0006520 103 0.845
notochord formation GO:0014028 5 0.845
negative regulation of cell development GO:0010721 169 0.843
retinal rod cell differentiation GO:0060221 2 0.842
ovarian follicle development GO:0001541 40 0.842
cell migration involved in sprouting angiogenesis GO:0002042 9 0.842
epithelial cell migration GO:0010631 63 0.841
Human
skeletal muscle cell differentiation GO:0035914 66 0.840
renal vesicle induction GO:0072034 3 0.840
connective tissue development GO:0061448 179 0.840
cellular chemical homeostasis GO:0055082 215 0.839
Mouse Rat
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.838
mesangial cell differentiation GO:0072007 4 0.836
regulation of transcription from rna polymerase ii promoter involved in forebrain neuron fate commitment GO:0021882 3 0.834
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.834
regulation of transferase activity GO:0051338 263 0.834
Human
mesoderm formation GO:0001707 62 0.833
labyrinthine layer development GO:0060711 49 0.833
response to transforming growth factor beta GO:0071559 88 0.833
Human Mouse Fly
regulation of epithelial cell migration GO:0010632 35 0.832
Human
regulation of peptide secretion GO:0002791 77 0.832
Fly
tricuspid valve formation GO:0003195 2 0.830
response to monosaccharide GO:0034284 67 0.826
muscle cell proliferation GO:0033002 52 0.825
Human
cardiac myofibril assembly GO:0055003 12 0.824
cardiac muscle tissue morphogenesis GO:0055008 44 0.823
negative regulation of axon extension GO:0030517 19 0.822
gland development GO:0048732 330 0.822
Human Mouse Rat
regulation of stem cell proliferation GO:0072091 78 0.820
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.819
myeloid cell differentiation GO:0030099 233 0.819
Mouse
mullerian duct regression GO:0001880 1 0.818
regulation of transcription from rna polymerase ii promoter by glucose GO:0000430 3 0.817
positive regulation of non canonical wnt signaling pathway GO:2000052 6 0.817
trophectodermal cellular morphogenesis GO:0001831 3 0.816
wound healing spreading of cells GO:0044319 8 0.816
positive regulation of protein modification process GO:0031401 299 0.816
Human Mouse
homeostasis of number of cells GO:0048872 210 0.816
regulation of response to wounding GO:1903034 189 0.815
multicellular organism growth GO:0035264 161 0.815
regulation of cell proliferation involved in heart morphogenesis GO:2000136 15 0.814
frontal suture morphogenesis GO:0060364 2 0.814
Rat
telencephalon cell migration GO:0022029 55 0.812
response to oxygen levels GO:0070482 62 0.812
Human
cell migration involved in gastrulation GO:0042074 13 0.809
morphogenesis of a branching structure GO:0001763 203 0.809
Mouse
amine metabolic process GO:0009308 45 0.808
positive regulation of cell death GO:0010942 224 0.806
striated muscle cell development GO:0055002 125 0.805
nucleus accumbens development GO:0021768 1 0.805
regulation of cell adhesion mediated by integrin GO:0033628 13 0.805
Human
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.805
endocardium development GO:0003157 10 0.805
mechanoreceptor differentiation GO:0042490 67 0.805
positive regulation of epithelial cell migration GO:0010634 19 0.801
Human
placenta development GO:0001890 140 0.800
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.800
somite development GO:0061053 81 0.800
regulation of smad protein import into nucleus GO:0060390 3 0.800
regulation of cellular response to growth factor stimulus GO:0090287 82 0.799
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.798
detection of external stimulus GO:0009581 61 0.797
cerebellar granule cell precursor proliferation GO:0021930 10 0.796
forebrain development GO:0030900 302 0.796
substrate dependent cell migration GO:0006929 18 0.796
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.795
keratinocyte development GO:0003334 10 0.792
noradrenergic neuron development GO:0003358 3 0.792
cell migration involved in coronary angiogenesis GO:0060981 1 0.786
oligodendrocyte differentiation GO:0048709 53 0.785
cerebral cortex development GO:0021987 86 0.785
negative regulation of glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000734 1 0.785
embryonic camera type eye development GO:0031076 36 0.785
somite specification GO:0001757 4 0.784
peptide hormone secretion GO:0030072 109 0.782
Fly
negative regulation of branching involved in ureteric bud morphogenesis GO:0090191 4 0.782
determination of left right symmetry GO:0007368 80 0.781
anatomical structure homeostasis GO:0060249 145 0.781
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.780
ureteric bud morphogenesis GO:0060675 62 0.780
renal capsule development GO:0072127 1 0.780
central nervous system neuron differentiation GO:0021953 162 0.778
glomerular endothelium development GO:0072011 2 0.776
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation GO:0021938 4 0.773
positive regulation of cellular amine metabolic process GO:0033240 5 0.772
mast cell differentiation GO:0060374 5 0.768
chondroblast differentiation GO:0060591 2 0.766
negative regulation of glial cell proliferation GO:0060253 4 0.766
axon target recognition GO:0007412 4 0.764
otic placode formation GO:0043049 1 0.763
striated muscle cell proliferation GO:0014855 39 0.757
Human
ascending aorta development GO:0035905 3 0.757
positive regulation of fibronectin dependent thymocyte migration GO:2000415 1 0.757
midbrain hindbrain boundary maturation GO:0021732 1 0.757
wnt signaling pathway involved in kidney development GO:0061289 2 0.756
negative regulation of neuron projection regeneration GO:0070571 3 0.755
regulation of system process GO:0044057 200 0.754
Human
metanephric nephron morphogenesis GO:0072273 19 0.753
corticotropin hormone secreting cell differentiation GO:0060128 3 0.752
renal capsule formation GO:0072129 1 0.751
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.751
Human Mouse
mesenchyme morphogenesis GO:0072132 32 0.750
regulation of thymocyte migration GO:2000410 2 0.750

Tgfb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.998
musculoskeletal system disease DOID:17 0 0.998
heart disease DOID:114 0 0.990
cardiovascular system disease DOID:1287 0 0.990
sensory system disease DOID:0050155 0 0.929
eye and adnexa disease DOID:1492 0 0.929
nervous system disease DOID:863 0 0.929
connective tissue disease DOID:65 0 0.889