Mus musculus

31 known processes

Thbs2

thrombospondin 2

(Aliases: TSP2,Thbs-2)

Thbs2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
connective tissue development GO:0061448 179 0.789
Mouse
extracellular matrix organization GO:0030198 147 0.777
cartilage development GO:0051216 140 0.662
Mouse
response to growth factor GO:0070848 198 0.646
Mouse
negative regulation of endothelial cell migration GO:0010596 4 0.623
regulation of plasminogen activation GO:0010755 4 0.612
cellular response to growth factor stimulus GO:0071363 197 0.592
Mouse
collagen fibril organization GO:0030199 32 0.560
positive regulation of cell adhesion GO:0045785 80 0.554
Mouse
negative regulation of hydrolase activity GO:0051346 71 0.537
positive regulation of proteolysis GO:0045862 85 0.531
cell adhesion GO:0007155 329 0.508
Mouse Fly
regulation of cell substrate adhesion GO:0010810 73 0.493
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.486
Mouse
extracellular structure organization GO:0043062 148 0.485
regulation of cell adhesion GO:0030155 154 0.484
Mouse
chondrocyte differentiation GO:0002062 72 0.459
bone development GO:0060348 120 0.441
Mouse
skeletal system morphogenesis GO:0048705 203 0.437
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.427
Mouse
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.384
anatomical structure homeostasis GO:0060249 145 0.359
regulation of cell motility GO:2000145 236 0.356
Mouse
cell substrate adhesion GO:0031589 130 0.351
Mouse
regulation of tissue remodeling GO:0034103 38 0.348
Mouse
negative regulation of cell adhesion GO:0007162 45 0.335
blood vessel morphogenesis GO:0048514 285 0.314
cellular response to oxidative stress GO:0034599 76 0.302
Mouse
engulfment of apoptotic cell GO:0043652 3 0.297
apoptotic signaling pathway GO:0097190 306 0.292
cell matrix adhesion GO:0007160 68 0.288
response to oxidative stress GO:0006979 123 0.284
Mouse
negative regulation of cell proliferation GO:0008285 296 0.280
Mouse
positive regulation of cell substrate adhesion GO:0010811 47 0.269
Mouse
regulation of system process GO:0044057 200 0.266
bone morphogenesis GO:0060349 78 0.256
Mouse
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.254
Mouse
growth plate cartilage development GO:0003417 14 0.252
Mouse
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.231
Mouse
positive regulation of programmed cell death GO:0043068 218 0.231
multicellular organismal homeostasis GO:0048871 164 0.226
negative regulation of cell substrate adhesion GO:0010812 16 0.222
regulation of proteolysis GO:0030162 164 0.213
regulation of ion transport GO:0043269 215 0.208
myeloid leukocyte migration GO:0097529 57 0.207
Mouse
regulation of peptidase activity GO:0052547 96 0.207
elastic fiber assembly GO:0048251 4 0.203
extrinsic apoptotic signaling pathway GO:0097191 126 0.191
positive regulation of peptidase activity GO:0010952 49 0.187
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.186
mesenchyme development GO:0060485 152 0.185
Mouse
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.185
lung development GO:0030324 164 0.184
regulation of ceramide biosynthetic process GO:2000303 1 0.183
leukocyte chemotaxis GO:0030595 69 0.178
Mouse
skeletal system development GO:0001501 356 0.177
Mouse
sensory organ morphogenesis GO:0090596 242 0.177
response to fibroblast growth factor GO:0071774 47 0.175
chemotaxis GO:0006935 247 0.174
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.174
Mouse
camera type eye development GO:0043010 266 0.172
bone trabecula morphogenesis GO:0061430 12 0.170
Mouse
ossification GO:0001503 216 0.170
Mouse
endothelial cell proliferation GO:0001935 27 0.170
Mouse
regulation of removal of superoxide radicals GO:2000121 4 0.167
muscle system process GO:0003012 141 0.166
regulation of mapk cascade GO:0043408 248 0.166
negative regulation of phospholipase activity GO:0010519 4 0.165
response to transforming growth factor beta GO:0071559 88 0.157
Mouse
developmental maturation GO:0021700 193 0.156
Mouse
negative regulation of fatty acid transport GO:2000192 1 0.155
protein maturation GO:0051604 176 0.154
tissue remodeling GO:0048771 102 0.153
Mouse
trabecula formation GO:0060343 24 0.153
Mouse
regulation of cellular response to growth factor stimulus GO:0090287 82 0.152
Mouse
cytokine production GO:0001816 319 0.150
positive regulation of cytokine production GO:0001819 174 0.149
tissue homeostasis GO:0001894 115 0.148
positive regulation of apoptotic process GO:0043065 217 0.146
endochondral bone growth GO:0003416 19 0.139
Mouse
peptide cross linking GO:0018149 10 0.135
regulation of fatty acid transport GO:2000191 10 0.134
regulation of cell migration GO:0030334 219 0.129
Mouse
angiogenesis GO:0001525 201 0.128
negative regulation of angiogenesis GO:0016525 25 0.128
muscle tissue development GO:0060537 308 0.128
intussusceptive angiogenesis GO:0002041 2 0.128
regulation of cartilage development GO:0061035 44 0.127
regulation of cytokine production GO:0001817 266 0.126
acetylcholine secretion neurotransmission GO:0014055 2 0.126
positive regulation of apoptotic signaling pathway GO:2001235 95 0.126
axonogenesis GO:0007409 274 0.125
axon guidance GO:0007411 141 0.124
digestive system development GO:0055123 200 0.121
regulation of tooth mineralization GO:0070170 2 0.119
mapk cascade GO:0000165 281 0.116
positive regulation of cell motility GO:2000147 116 0.115
Mouse
transmembrane transport GO:0055085 412 0.114
organic anion transport GO:0015711 137 0.114
positive regulation of protein phosphorylation GO:0001934 242 0.112
heart morphogenesis GO:0003007 178 0.112
Mouse
fibril organization GO:0097435 2 0.106
regulation of reactive oxygen species metabolic process GO:2000377 40 0.106
inflammatory response GO:0006954 244 0.105
Mouse
regulation of inflammatory response GO:0050727 147 0.104
proteoglycan metabolic process GO:0006029 38 0.104
respiratory tube development GO:0030323 167 0.101
biomineral tissue development GO:0031214 64 0.101
synaptic transmission GO:0007268 329 0.100
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.099
epithelial cell proliferation GO:0050673 174 0.099
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.098
regulation of cellular component biogenesis GO:0044087 181 0.098
response to reactive oxygen species GO:0000302 56 0.097
Mouse
negative regulation of growth GO:0045926 99 0.096
antibacterial peptide biosynthetic process GO:0002780 2 0.095
anion transport GO:0006820 177 0.095
regulation of endopeptidase activity GO:0052548 89 0.093
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.093
Mouse
regulation of chondrocyte differentiation GO:0032330 33 0.092
positive regulation of protein modification process GO:0031401 299 0.091
reactive oxygen species metabolic process GO:0072593 84 0.088
positive regulation of nervous system development GO:0051962 221 0.087
cation transport GO:0006812 399 0.087
positive regulation of cell death GO:0010942 224 0.086
regulation of organ morphogenesis GO:2000027 144 0.085
positive regulation of cellular amine metabolic process GO:0033240 5 0.083
response to organonitrogen compound GO:0010243 246 0.083
protein processing GO:0016485 163 0.083
regulation of biomineral tissue development GO:0070167 33 0.080
protein kinase b signaling GO:0043491 74 0.079
regulation of cellular response to stress GO:0080135 159 0.079
regulation of hydrolase activity GO:0051336 246 0.079
regulation of chemotaxis GO:0050920 53 0.078
Mouse
regulation of blood coagulation GO:0030193 28 0.078
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.078
negative regulation of apoptotic signaling pathway GO:2001234 104 0.078
bone mineralization GO:0030282 54 0.077
fat cell differentiation GO:0045444 160 0.077
regulation of sphingolipid biosynthetic process GO:0090153 1 0.077
positive regulation of bone remodeling GO:0046852 13 0.076
bmp signaling pathway GO:0030509 93 0.075
positive regulation of phospholipase activity GO:0010518 3 0.074
organ growth GO:0035265 117 0.074
Mouse
embryonic placenta development GO:0001892 98 0.074
regulation of apoptotic signaling pathway GO:2001233 197 0.073
negative regulation of cell migration GO:0030336 59 0.073
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.072
Mouse
digestive tract morphogenesis GO:0048546 147 0.072
regulation of defense response GO:0031347 233 0.070
negative regulation of blood vessel morphogenesis GO:2000181 25 0.070
protein heterotrimerization GO:0070208 8 0.070
striated muscle tissue development GO:0014706 293 0.070
regulation of cysteine type endopeptidase activity GO:2000116 65 0.069
neuron migration GO:0001764 122 0.068
negative regulation of vasculature development GO:1901343 26 0.067
cartilage condensation GO:0001502 18 0.067
physiological cardiac muscle hypertrophy GO:0003301 3 0.067
endochondral bone morphogenesis GO:0060350 50 0.066
Mouse
carboxylic acid transport GO:0046942 100 0.066
placenta development GO:0001890 140 0.066
regulation of secretion GO:0051046 274 0.066
regulation of neurotransmitter levels GO:0001505 87 0.065
multicellular organismal response to stress GO:0033555 62 0.065
Mouse
cellular response to acid chemical GO:0071229 68 0.064
wound healing GO:0042060 157 0.063
respiratory system development GO:0060541 190 0.063
trabecula morphogenesis GO:0061383 40 0.062
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.062
cellular response to cytokine stimulus GO:0071345 189 0.061
regulation of hormone levels GO:0010817 211 0.061
stem cell differentiation GO:0048863 268 0.061
single organism cell adhesion GO:0098602 156 0.061
regulation of neuron projection development GO:0010975 169 0.060
cognition GO:0050890 149 0.060
neuron projection guidance GO:0097485 141 0.060
muscle cell development GO:0055001 133 0.060
regulation of cellular ketone metabolic process GO:0010565 66 0.059
epidermis development GO:0008544 187 0.059
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.058
response to radiation GO:0009314 165 0.058
negative regulation of tooth mineralization GO:0070171 1 0.057
regulation of muscle system process GO:0090257 80 0.057
response to inorganic substance GO:0010035 96 0.057
Mouse
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.057
inner ear morphogenesis GO:0042472 101 0.057
skeletal muscle organ development GO:0060538 163 0.056
Fly
defense response to bacterium GO:0042742 119 0.056
peptide metabolic process GO:0006518 46 0.055
developmental programmed cell death GO:0010623 41 0.055
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.054
protein oligomerization GO:0051259 67 0.054
regulation of angiogenesis GO:0045765 81 0.054
appendage development GO:0048736 166 0.054
negative regulation of molecular function GO:0044092 258 0.054
retinal blood vessel morphogenesis GO:0061304 3 0.052
ear development GO:0043583 200 0.052
response to organic cyclic compound GO:0014070 198 0.051
bone resorption GO:0045453 38 0.051
progesterone secretion GO:0042701 1 0.050
sulfur compound metabolic process GO:0006790 100 0.050
bone trabecula formation GO:0060346 9 0.050
Mouse
cellular response to amino acid stimulus GO:0071230 29 0.050
negative regulation of phosphorus metabolic process GO:0010563 184 0.050
regulation of epithelial cell proliferation GO:0050678 141 0.049
Mouse
extracellular fibril organization GO:0043206 2 0.049
positive regulation of angiogenesis GO:0045766 46 0.049
odontogenesis GO:0042476 78 0.049
response to amino acid GO:0043200 37 0.049
pallium development GO:0021543 120 0.048
cellular amide metabolic process GO:0043603 58 0.048
regulation of neuron differentiation GO:0045664 281 0.048
muscle cell differentiation GO:0042692 261 0.048
renal system development GO:0072001 225 0.048
regulation of cellular response to oxidative stress GO:1900407 19 0.048
gland development GO:0048732 330 0.047
regulation of macrophage migration inhibitory factor signaling pathway GO:2000446 1 0.047
regulation of response to wounding GO:1903034 189 0.047
positive regulation of protein kinase b signaling GO:0051897 32 0.047
negative regulation of protein activation cascade GO:2000258 3 0.046
smooth muscle contraction GO:0006939 44 0.046
regulation of response to oxidative stress GO:1902882 19 0.046
synaptic transmission cholinergic GO:0007271 7 0.046
cellular response to prostaglandin stimulus GO:0071379 2 0.045
antibacterial peptide production GO:0002778 2 0.045
locomotory behavior GO:0007626 195 0.045
signal transduction in absence of ligand GO:0038034 55 0.044
chondroblast differentiation GO:0060591 2 0.044
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.044
peripheral nervous system axon regeneration GO:0014012 2 0.044
macrophage chemotaxis GO:0048246 14 0.044
Mouse
erk1 and erk2 cascade GO:0070371 77 0.044
regulation of body fluid levels GO:0050878 162 0.043
activation of mapk activity GO:0000187 59 0.043
single organismal cell cell adhesion GO:0016337 131 0.043
positive regulation of axon extension GO:0045773 20 0.043
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.043
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
response to endoplasmic reticulum stress GO:0034976 53 0.043
Mouse
regulation of vasculature development GO:1901342 88 0.043
cell chemotaxis GO:0060326 81 0.043
Mouse
cell growth involved in cardiac muscle cell development GO:0061049 3 0.042
negative regulation of protein processing GO:0010955 79 0.042
regulation of fibrinolysis GO:0051917 1 0.042
regulation of ion transmembrane transport GO:0034765 119 0.040
embryonic organ morphogenesis GO:0048562 276 0.040
circulatory system process GO:0003013 197 0.040
negative regulation of macrophage chemotaxis GO:0010760 1 0.040
sensory perception of light stimulus GO:0050953 54 0.040
positive regulation of cell migration GO:0030335 109 0.040
Mouse
regulation of macrophage chemotaxis GO:0010758 8 0.040
Mouse
organic acid transport GO:0015849 101 0.040
gliogenesis GO:0042063 141 0.040
acetylcholine transport GO:0015870 2 0.039
antimicrobial peptide biosynthetic process GO:0002777 2 0.039
membrane lipid biosynthetic process GO:0046467 32 0.039
positive regulation of fatty acid oxidation GO:0046321 4 0.039
response to lipopolysaccharide GO:0032496 128 0.039
cellular response to organonitrogen compound GO:0071417 145 0.038
cardiac chamber development GO:0003205 108 0.038
aminoglycan metabolic process GO:0006022 34 0.038
granulocyte migration GO:0097530 43 0.038
Mouse
positive regulation of kinase activity GO:0033674 155 0.038
positive regulation of response to wounding GO:1903036 66 0.038
lipid transport GO:0006869 98 0.038
macromolecule catabolic process GO:0009057 281 0.038
regulation of cell growth involved in cardiac muscle cell development GO:0061050 3 0.037
removal of superoxide radicals GO:0019430 12 0.037
muscle fiber development GO:0048747 76 0.037
regulation of secretion by cell GO:1903530 249 0.037
negative regulation of epithelial cell proliferation GO:0050680 64 0.037
Mouse
insemination GO:0007320 6 0.036
long term synaptic potentiation GO:0060291 25 0.036
negative regulation of odontogenesis GO:0042483 3 0.036
negative regulation of cell motility GO:2000146 61 0.036
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.035
chondrocyte development GO:0002063 24 0.035
defense response to other organism GO:0098542 197 0.035
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.035
positive regulation of macrophage chemotaxis GO:0010759 5 0.035
Mouse
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.035
response to molecule of bacterial origin GO:0002237 143 0.035
ameboidal type cell migration GO:0001667 128 0.035
regulation of cell projection organization GO:0031344 206 0.034
mononuclear cell migration GO:0071674 8 0.034
Mouse
regulation of map kinase activity GO:0043405 120 0.034
positive regulation of mapk cascade GO:0043410 170 0.034
cell type specific apoptotic process GO:0097285 268 0.034
nitrogen compound transport GO:0071705 271 0.034
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.034
cardiac chamber morphogenesis GO:0003206 93 0.034
replacement ossification GO:0036075 26 0.033
negative regulation of phosphorylation GO:0042326 166 0.033
limb development GO:0060173 166 0.033
ceramide biosynthetic process GO:0046513 20 0.033
cellular ketone metabolic process GO:0042180 84 0.033
urogenital system development GO:0001655 261 0.033
negative regulation of endopeptidase activity GO:0010951 44 0.033
ion transmembrane transport GO:0034220 361 0.032
regulation of lipid transport GO:0032368 36 0.032
cellular response to lipid GO:0071396 145 0.032
cellular response to oxygen radical GO:0071450 14 0.032
regulation of erk1 and erk2 cascade GO:0070372 71 0.031
response to hypoxia GO:0001666 58 0.031
regulation of lymphocyte activation GO:0051249 240 0.031
positive regulation of neuron differentiation GO:0045666 141 0.031
regulation of anatomical structure size GO:0090066 178 0.031
regulation of bone resorption GO:0045124 24 0.030
limb morphogenesis GO:0035108 149 0.030
sensory perception of mechanical stimulus GO:0050954 107 0.030
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.030
i kappab kinase nf kappab signaling GO:0007249 85 0.030
development of primary female sexual characteristics GO:0046545 73 0.029
endomembrane system organization GO:0010256 147 0.029
neuromuscular process GO:0050905 99 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
regulation of anion transport GO:0044070 27 0.029
sensory perception of sound GO:0007605 97 0.029
regulation of ossification GO:0030278 112 0.029
negative regulation of phosphate metabolic process GO:0045936 184 0.029
positive regulation of bone resorption GO:0045780 13 0.029
regulation of transmembrane transport GO:0034762 128 0.029
negative regulation of ion transport GO:0043271 28 0.028
peptide hormone processing GO:0016486 9 0.028
positive regulation of sphingolipid biosynthetic process GO:0090154 1 0.028
b cell activation GO:0042113 161 0.028
lateral line system development GO:0048925 1 0.028
regulation of bmp signaling pathway GO:0030510 60 0.028
negative regulation of cell proliferation involved in contact inhibition GO:0060244 3 0.028
positive regulation of defense response GO:0031349 124 0.028
glycoprotein metabolic process GO:0009100 116 0.028
cellular response to external stimulus GO:0071496 88 0.028
tumor necrosis factor production GO:0032640 50 0.027
sensory perception GO:0007600 245 0.027
regulation of bone remodeling GO:0046850 28 0.027
forebrain development GO:0030900 302 0.027
cell growth GO:0016049 130 0.027
regulation of coagulation GO:0050818 31 0.027
insulin processing GO:0030070 2 0.026
regulation of establishment of protein localization GO:0070201 181 0.026
renal system process GO:0003014 48 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
positive regulation of endopeptidase activity GO:0010950 43 0.026
amine metabolic process GO:0009308 45 0.026
neurotransmitter secretion GO:0007269 62 0.026
regulation of cardiac muscle hypertrophy GO:0010611 13 0.026
blood circulation GO:0008015 195 0.026
spermatogenesis GO:0007283 284 0.026
response to pain GO:0048265 26 0.026
Mouse
negative regulation of cellular component organization GO:0051129 194 0.026
antibacterial peptide secretion GO:0002779 1 0.026
regulation of synaptic plasticity GO:0048167 87 0.026
digestive tract development GO:0048565 190 0.026
regulation of cell activation GO:0050865 289 0.026
apoptotic process involved in morphogenesis GO:0060561 25 0.026
second messenger mediated signaling GO:0019932 73 0.026
t cell activation GO:0042110 289 0.025
positive regulation of adiponectin secretion GO:0070165 1 0.025
multi multicellular organism process GO:0044706 109 0.025
regulation of protein serine threonine kinase activity GO:0071900 157 0.025
regulation of protein kinase activity GO:0045859 232 0.025
ear morphogenesis GO:0042471 118 0.025
immune effector process GO:0002252 321 0.025
response to light stimulus GO:0009416 135 0.025
monocarboxylic acid metabolic process GO:0032787 191 0.024
rhythmic process GO:0048511 174 0.024
positive regulation of hydrolase activity GO:0051345 148 0.024
regulation of mononuclear cell migration GO:0071675 6 0.024
Mouse
ovulation cycle GO:0042698 59 0.024
physiological muscle hypertrophy GO:0003298 3 0.024
divalent inorganic cation transport GO:0072511 178 0.024
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.024
oxidation reduction process GO:0055114 342 0.024
mucopolysaccharide metabolic process GO:1903510 25 0.023
vascular process in circulatory system GO:0003018 62 0.023
developmental cell growth GO:0048588 84 0.023
regulation of hemostasis GO:1900046 28 0.023
positive regulation of map kinase activity GO:0043406 84 0.023
regulation of endothelial cell apoptotic process GO:2000351 9 0.023
regulation of protein processing GO:0070613 96 0.023
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.023
epithelial tube morphogenesis GO:0060562 303 0.023
cyclic nucleotide metabolic process GO:0009187 59 0.023
deltoid tuberosity development GO:0035993 3 0.023
regulation of protein maturation GO:1903317 96 0.023
lipid oxidation GO:0034440 29 0.022
antimicrobial peptide secretion GO:0002776 1 0.022
protein heterooligomerization GO:0051291 14 0.022
hormone secretion GO:0046879 128 0.022
organic hydroxy compound metabolic process GO:1901615 203 0.022
apoptotic process involved in development GO:1902742 28 0.022
lung alveolus development GO:0048286 45 0.022
acetate ester transport GO:1901374 2 0.022
regulation of fatty acid oxidation GO:0046320 10 0.022
conditioned taste aversion GO:0001661 4 0.022
cation transmembrane transport GO:0098655 266 0.022
import into cell GO:0098657 8 0.022
regulation of cardiac muscle tissue growth GO:0055021 26 0.022
regulation of homeostatic process GO:0032844 182 0.022
production of molecular mediator of immune response GO:0002440 103 0.021
regulation of cell size GO:0008361 72 0.021
divalent metal ion transport GO:0070838 172 0.021
monocarboxylic acid transport GO:0015718 44 0.021
regionalization GO:0003002 337 0.021
cellular polysaccharide metabolic process GO:0044264 38 0.021
striated muscle cell development GO:0055002 125 0.021
regulation of cellular amine metabolic process GO:0033238 20 0.021
neuromuscular process controlling balance GO:0050885 59 0.021
positive regulation of lipid biosynthetic process GO:0046889 18 0.021
peptide cross linking via chondroitin 4 sulfate glycosaminoglycan GO:0019800 8 0.021
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.021
protein catabolic process GO:0030163 221 0.021
positive regulation of cell development GO:0010720 237 0.021
metencephalon development GO:0022037 89 0.021
regulation of transferase activity GO:0051338 263 0.021
regulation of protein secretion GO:0050708 82 0.020
sprouting angiogenesis GO:0002040 26 0.020
translation GO:0006412 93 0.020
jnk cascade GO:0007254 72 0.020
sphingolipid biosynthetic process GO:0030148 26 0.020
neuron neuron synaptic transmission GO:0007270 69 0.020
regulation of smoothened signaling pathway GO:0008589 58 0.020
regulation of tumor necrosis factor production GO:0032680 49 0.020
positive regulation of homeostatic process GO:0032846 64 0.020
cardiac ventricle development GO:0003231 83 0.020
regulation of protein transport GO:0051223 163 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.020
cytokine metabolic process GO:0042107 71 0.020
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.020
smoothened signaling pathway GO:0007224 105 0.020
cytokine mediated signaling pathway GO:0019221 115 0.019
negative regulation of fibrinolysis GO:0051918 1 0.019
regulation of translation GO:0006417 71 0.019
branching involved in salivary gland morphogenesis GO:0060445 26 0.019
positive regulation of tissue remodeling GO:0034105 19 0.019
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.019
telencephalon development GO:0021537 186 0.019
regulation of kinase activity GO:0043549 249 0.019
zymogen activation GO:0031638 41 0.019
regulation of cytokine secretion GO:0050707 61 0.019
skin development GO:0043588 220 0.019
positive regulation of cell activation GO:0050867 158 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
endoderm formation GO:0001706 20 0.019
muscle cell proliferation GO:0033002 52 0.019
thymocyte migration GO:0072679 2 0.019
fibroblast migration GO:0010761 21 0.019
peptidyl serine modification GO:0018209 83 0.018
glial cell differentiation GO:0010001 131 0.018
multicellular organismal catabolic process GO:0044243 7 0.018
cellular glucan metabolic process GO:0006073 32 0.018
negative regulation of protein maturation GO:1903318 79 0.018
antimicrobial peptide production GO:0002775 2 0.018
cellular response to lipopolysaccharide GO:0071222 77 0.018
stem cell proliferation GO:0072089 117 0.018
regulation of multi organism process GO:0043900 111 0.018
negative regulation of proteolysis GO:0045861 74 0.018
cellular response to x ray GO:0071481 2 0.018
epithelial cell development GO:0002064 159 0.018
regulation of thymocyte migration GO:2000410 2 0.017
membrane organization GO:0061024 245 0.017
metal ion homeostasis GO:0055065 189 0.017
purine containing compound metabolic process GO:0072521 311 0.017
positive regulation of thymocyte migration GO:2000412 2 0.017
positive regulation of camp mediated signaling GO:0043950 3 0.017
female gonad development GO:0008585 71 0.017
positive regulation of eosinophil migration GO:2000418 2 0.017
antibacterial humoral response GO:0019731 8 0.017
regulation of morphogenesis of a branching structure GO:0060688 53 0.017
positive regulation of semaphorin plexin signaling pathway GO:2001262 1 0.017
bone maturation GO:0070977 13 0.017
Mouse
negative regulation of immune system process GO:0002683 209 0.017
protein autoprocessing GO:0016540 2 0.017
fatty acid transmembrane transport GO:1902001 1 0.017
lipid localization GO:0010876 126 0.017
embryonic skeletal system development GO:0048706 120 0.017
kidney development GO:0001822 213 0.017
regulation of reproductive process GO:2000241 66 0.017
canonical wnt signaling pathway GO:0060070 130 0.017
negative regulation of mapk cascade GO:0043409 65 0.017
adult behavior GO:0030534 135 0.016

Thbs2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.268
muscular disease DOID:0080000 0 0.268
disease of anatomical entity DOID:7 0 0.268
musculoskeletal system disease DOID:17 0 0.268
muscle tissue disease DOID:66 0 0.268
heart disease DOID:114 0 0.039
cardiovascular system disease DOID:1287 0 0.039
retinal disease DOID:5679 0 0.030
retinal degeneration DOID:8466 0 0.030
sensory system disease DOID:0050155 0 0.030
eye and adnexa disease DOID:1492 0 0.030
nervous system disease DOID:863 0 0.030
eye disease DOID:5614 0 0.030
congenital muscular dystrophy DOID:0050557 0 0.020
muscular dystrophy DOID:9884 0 0.020