Mus musculus

0 known processes

Thoc3

THO complex 3

(Aliases: AL033344,2410044K02Rik)

Thoc3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna metabolic process GO:0016071 84 0.161
mrna splicing via spliceosome GO:0000398 43 0.153
cellular response to dna damage stimulus GO:0006974 207 0.125
rna processing GO:0006396 105 0.120
aromatic compound catabolic process GO:0019439 286 0.105
covalent chromatin modification GO:0016569 163 0.104
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.097
peptidyl amino acid modification GO:0018193 336 0.092
organic cyclic compound catabolic process GO:1901361 295 0.091
dna metabolic process GO:0006259 303 0.087
ribose phosphate metabolic process GO:0019693 291 0.085
regulation of cellular amine metabolic process GO:0033238 20 0.073
rna splicing via transesterification reactions GO:0000375 43 0.073
gonad development GO:0008406 141 0.071
ncrna processing GO:0034470 26 0.070
amine metabolic process GO:0009308 45 0.063
dna repair GO:0006281 107 0.061
purine nucleotide metabolic process GO:0006163 302 0.059
dephosphorylation GO:0016311 129 0.058
cellular ketone metabolic process GO:0042180 84 0.056
chromatin organization GO:0006325 206 0.054
histone modification GO:0016570 159 0.051
regulation of cellular amino acid metabolic process GO:0006521 5 0.050
regulation of cell cycle GO:0051726 281 0.049
rna splicing GO:0008380 54 0.049
ribonucleotide metabolic process GO:0009259 291 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.049
mitochondrion organization GO:0007005 134 0.046
positive regulation of cellular amine metabolic process GO:0033240 5 0.045
cytoplasmic transport GO:0016482 234 0.044
Human
heterocycle catabolic process GO:0046700 280 0.043
glycosyl compound metabolic process GO:1901657 246 0.042
chromatin modification GO:0016568 187 0.042
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.041
cellular nitrogen compound catabolic process GO:0044270 280 0.040
nucleoside metabolic process GO:0009116 246 0.039
nucleoside phosphate metabolic process GO:0006753 338 0.039
purine containing compound metabolic process GO:0072521 311 0.038
nucleoside monophosphate metabolic process GO:0009123 85 0.038
negative regulation of cellular component organization GO:0051129 194 0.037
development of primary sexual characteristics GO:0045137 143 0.037
ribonucleoside triphosphate metabolic process GO:0009199 220 0.036
purine ribonucleotide metabolic process GO:0009150 290 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
cell fate commitment GO:0045165 210 0.033
protein acylation GO:0043543 64 0.032
nucleotide metabolic process GO:0009117 332 0.032
establishment of rna localization GO:0051236 18 0.032
Human
nucleoside triphosphate catabolic process GO:0009143 205 0.032
gland development GO:0048732 330 0.030
endocytosis GO:0006897 168 0.030
regionalization GO:0003002 337 0.030
mrna processing GO:0006397 63 0.029
nucleotide catabolic process GO:0009166 217 0.029
mapk cascade GO:0000165 281 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.027
cellular amine metabolic process GO:0044106 44 0.027
organelle fission GO:0048285 170 0.027
germ cell development GO:0007281 185 0.026
mrna transport GO:0051028 13 0.026
Human
peptidyl lysine modification GO:0018205 77 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
nitrogen compound transport GO:0071705 271 0.026
Human
mitotic recombination GO:0006312 3 0.026
response to oxidative stress GO:0006979 123 0.026
regulation of organelle organization GO:0033043 289 0.025
regulation of cell cycle process GO:0010564 160 0.025
positive regulation of protein modification process GO:0031401 299 0.024
membrane organization GO:0061024 245 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
dna recombination GO:0006310 92 0.024
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
histone acetylation GO:0016573 41 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
purine nucleoside catabolic process GO:0006152 205 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
ribonucleoside monophosphate metabolic process GO:0009161 80 0.022
macromolecule catabolic process GO:0009057 281 0.022
purine nucleotide catabolic process GO:0006195 211 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
trna wobble uridine modification GO:0002098 2 0.021
receptor mediated endocytosis GO:0006898 51 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
cellular amino acid metabolic process GO:0006520 103 0.020
nuclear division GO:0000280 158 0.020
nucleoside phosphate catabolic process GO:1901292 222 0.020
meiotic cell cycle process GO:1903046 77 0.020
nucleotide biosynthetic process GO:0009165 78 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.019
mitotic cell cycle GO:0000278 195 0.019
meiotic cell cycle GO:0051321 122 0.018
protein localization to organelle GO:0033365 185 0.018
microtubule based process GO:0007017 236 0.018
endomembrane system organization GO:0010256 147 0.018
organophosphate catabolic process GO:0046434 232 0.018
nucleoside phosphate biosynthetic process GO:1901293 79 0.018
methylation GO:0032259 134 0.018
rrna processing GO:0006364 10 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
ribonucleotide catabolic process GO:0009261 208 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
regulation of hydrolase activity GO:0051336 246 0.017
maturation of 5 8s rrna GO:0000460 1 0.017
purine nucleoside monophosphate metabolic process GO:0009126 81 0.017
organelle assembly GO:0070925 177 0.017
ribosome biogenesis GO:0042254 20 0.017
histone methylation GO:0016571 71 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
cellular macromolecule catabolic process GO:0044265 206 0.016
internal peptidyl lysine acetylation GO:0018393 42 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
negative regulation of apoptotic signaling pathway GO:2001234 104 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.016
negative regulation of molecular function GO:0044092 258 0.016
regulation of protein localization GO:0032880 231 0.016
cellular protein complex assembly GO:0043623 116 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
meiosis i GO:0007127 60 0.015
female gamete generation GO:0007292 74 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.015
oogenesis GO:0048477 56 0.015
internal protein amino acid acetylation GO:0006475 42 0.015
response to organic cyclic compound GO:0014070 198 0.015
multicellular organism growth GO:0035264 161 0.015
positive regulation of cell death GO:0010942 224 0.015
double strand break repair GO:0006302 48 0.015
regulation of response to dna damage stimulus GO:2001020 34 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
regulation of establishment of protein localization GO:0070201 181 0.014
purine containing compound catabolic process GO:0072523 213 0.014
rna transport GO:0050658 18 0.014
Human
nuclear transport GO:0051169 139 0.014
Human
apoptotic signaling pathway GO:0097190 306 0.014
multicellular organismal signaling GO:0035637 91 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
peptidyl lysine acetylation GO:0018394 45 0.014
protein catabolic process GO:0030163 221 0.014
response to radiation GO:0009314 165 0.014
ribonucleoprotein complex subunit organization GO:0071826 28 0.014
macromolecule methylation GO:0043414 120 0.014
regulation of cellular response to stress GO:0080135 159 0.014
stem cell differentiation GO:0048863 268 0.014
meiotic nuclear division GO:0007126 115 0.013
regulation of mapk cascade GO:0043408 248 0.013
oocyte construction GO:0007308 2 0.013
action potential GO:0001508 78 0.013
nuclear transcribed mrna catabolic process GO:0000956 16 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
ras protein signal transduction GO:0007265 77 0.013
genitalia development GO:0048806 37 0.013
negative regulation of myeloid cell differentiation GO:0045638 38 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
positive regulation of organelle organization GO:0010638 128 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
response to growth factor GO:0070848 198 0.013
spermatogenesis GO:0007283 284 0.013
leukocyte differentiation GO:0002521 342 0.013
cell adhesion GO:0007155 329 0.013
regulation of kinase activity GO:0043549 249 0.013
regulation of histone modification GO:0031056 56 0.013
oocyte axis specification GO:0007309 2 0.013
response to organonitrogen compound GO:0010243 246 0.013
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 1 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
regulation of intracellular transport GO:0032386 159 0.012
trna wobble base modification GO:0002097 2 0.012
cation transport GO:0006812 399 0.012
apoptotic mitochondrial changes GO:0008637 48 0.012
positive regulation of cell development GO:0010720 237 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
segmentation GO:0035282 93 0.012
regulation of chromatin modification GO:1903308 57 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
male gamete generation GO:0048232 285 0.012
response to light stimulus GO:0009416 135 0.012
forebrain development GO:0030900 302 0.012
regulation of mitotic cell cycle phase transition GO:1901990 73 0.012
ribonucleoside monophosphate catabolic process GO:0009158 57 0.012
protein targeting GO:0006605 143 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
nucleoside catabolic process GO:0009164 206 0.012
wnt signaling pathway GO:0016055 188 0.012
telencephalon development GO:0021537 186 0.012
negative regulation of immune system process GO:0002683 209 0.011
dna dependent dna replication GO:0006261 24 0.011
regulation of protein transport GO:0051223 163 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
negative regulation of organelle organization GO:0010639 90 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
negative regulation of protein metabolic process GO:0051248 282 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
neuronal action potential GO:0019228 54 0.011
t cell activation GO:0042110 289 0.011
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.011
regulation of mrna metabolic process GO:1903311 43 0.011
intracellular protein transport GO:0006886 204 0.011
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 10 0.011
regulation of chromatin organization GO:1902275 57 0.011
rna catabolic process GO:0006401 29 0.011
regulation of rna splicing GO:0043484 37 0.011
regulation of transferase activity GO:0051338 263 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
homeostasis of number of cells GO:0048872 210 0.011
regulation of ras protein signal transduction GO:0046578 114 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
axonogenesis GO:0007409 274 0.010
regulation of cellular response to growth factor stimulus GO:0090287 82 0.010
positive regulation of growth GO:0045927 104 0.010
lipid biosynthetic process GO:0008610 179 0.010
regulation of cell migration GO:0030334 219 0.010
protein ubiquitination GO:0016567 171 0.010
regulation of cell activation GO:0050865 289 0.010
transcription coupled nucleotide excision repair GO:0006283 2 0.010
regulation of secretion by cell GO:1903530 249 0.010
striated muscle myosin thick filament assembly GO:0071688 1 0.010
ribonucleoside catabolic process GO:0042454 206 0.010
transmembrane transport GO:0055085 412 0.010

Thoc3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.016
disease of mental health DOID:150 0 0.015
central nervous system disease DOID:331 0 0.012
disease of anatomical entity DOID:7 0 0.012
neurodegenerative disease DOID:1289 0 0.012
nervous system disease DOID:863 0 0.012