Mus musculus

280 known processes

Thra

thyroid hormone receptor alpha

(Aliases: T3R[a],T3Ralpha,Nr1a1,AW259572,Rvr,Thra1,Thra2,Erba,6430529J03Rik)

Thra biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
type i pneumocyte differentiation GO:0060509 7 1.000
regulation of feeding behavior GO:0060259 3 0.997
retinal cone cell development GO:0046549 8 0.992
cholesterol homeostasis GO:0042632 44 0.988
Mouse
sensory perception of umami taste GO:0050917 4 0.969
multicellular organism growth GO:0035264 161 0.967
Mouse
generation of precursor metabolites and energy GO:0006091 103 0.961
Mouse
limb development GO:0060173 166 0.955
Mouse
cellular modified amino acid metabolic process GO:0006575 63 0.951
positive regulation of steroid biosynthetic process GO:0010893 4 0.942
Mouse
regulation of triglyceride metabolic process GO:0090207 17 0.932
carbohydrate metabolic process GO:0005975 230 0.925
Mouse
appendage development GO:0048736 166 0.924
Mouse
positive regulation of neurotransmitter transport GO:0051590 9 0.923
connective tissue development GO:0061448 179 0.921
clara cell differentiation GO:0060486 4 0.916
cellular carbohydrate metabolic process GO:0044262 119 0.909
Mouse
endochondral bone morphogenesis GO:0060350 50 0.902
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.900
Mouse
bone development GO:0060348 120 0.896
Mouse
energy reserve metabolic process GO:0006112 39 0.894
Mouse
acetylcholine transport GO:0015870 2 0.880
regulation of intracellular transport GO:0032386 159 0.873
retinal cone cell differentiation GO:0042670 8 0.861
osteoclast differentiation GO:0030316 62 0.858
cellular amino acid metabolic process GO:0006520 103 0.842
regulation of myeloid leukocyte differentiation GO:0002761 58 0.837
Mouse
eye photoreceptor cell development GO:0042462 31 0.836
oxidation reduction process GO:0055114 342 0.811
Mouse
lung epithelium development GO:0060428 37 0.804
skeletal system morphogenesis GO:0048705 203 0.802
negative regulation of translational initiation GO:0045947 4 0.789
Mouse
morphogenesis of a branching structure GO:0001763 203 0.786
acetylcholine secretion neurotransmission GO:0014055 2 0.785
epithelial tube morphogenesis GO:0060562 303 0.782
Mouse
telencephalon development GO:0021537 186 0.782
Mouse
embryonic limb morphogenesis GO:0030326 126 0.782
Mouse
regulation of fat cell differentiation GO:0045598 81 0.773
Mouse
camp metabolic process GO:0046058 40 0.771
forebrain development GO:0030900 302 0.756
Mouse
fat cell differentiation GO:0045444 160 0.743
Mouse
regulation of circadian rhythm GO:0042752 58 0.722
Mouse
photoreceptor cell development GO:0042461 40 0.714
erythrocyte differentiation GO:0030218 88 0.713
myeloid leukocyte differentiation GO:0002573 119 0.695
Mouse
proteasomal protein catabolic process GO:0010498 98 0.690
Mouse
regulation of neurotransmitter levels GO:0001505 87 0.673
limb morphogenesis GO:0035108 149 0.667
Mouse
female mating behavior GO:0060180 8 0.665
regulation of cholesterol homeostasis GO:2000188 9 0.661
Mouse
cyclic purine nucleotide metabolic process GO:0052652 43 0.648
negative regulation of epithelial cell proliferation GO:0050680 64 0.647
acylglycerol metabolic process GO:0006639 55 0.637
regulation of hormone levels GO:0010817 211 0.623
Mouse
negative regulation of mesenchymal cell proliferation involved in lung development GO:2000791 2 0.620
cellular protein catabolic process GO:0044257 155 0.615
Mouse
thyroid hormone metabolic process GO:0042403 16 0.612
extrinsic apoptotic signaling pathway GO:0097191 126 0.610
multi organism reproductive behavior GO:0044705 29 0.600
positive regulation of innate immune response GO:0045089 80 0.597
photoreceptor cell differentiation GO:0046530 52 0.596
regulation of phospholipase c activity GO:1900274 3 0.593
protein import GO:0017038 101 0.593
regulation of mesenchymal cell proliferation involved in lung development GO:2000790 2 0.586
ossification GO:0001503 216 0.586
bone morphogenesis GO:0060349 78 0.582
Mouse
lactation GO:0007595 25 0.579
neutral lipid metabolic process GO:0006638 57 0.577
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.576
skeletal system development GO:0001501 356 0.573
regulation of protein targeting GO:1903533 61 0.569
positive regulation of fatty acid oxidation GO:0046321 4 0.565
protein localization to organelle GO:0033365 185 0.564
sterol homeostasis GO:0055092 45 0.556
Mouse
regulation of receptor activity GO:0010469 41 0.554
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.550
Mouse
regionalization GO:0003002 337 0.548
Mouse
neural tube closure GO:0001843 90 0.546
Mouse
gland development GO:0048732 330 0.532
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.530
negative regulation of female receptivity GO:0007621 2 0.524
Mouse
regulation of binding GO:0051098 111 0.519
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.519
energy derivation by oxidation of organic compounds GO:0015980 77 0.514
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.503
Mouse
regulation of peptide secretion GO:0002791 77 0.503
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.501
Mouse
growth plate cartilage development GO:0003417 14 0.493
Mouse
triglyceride metabolic process GO:0006641 51 0.484
appendage morphogenesis GO:0035107 149 0.484
Mouse
eating behavior GO:0042755 15 0.479
nitrogen compound transport GO:0071705 271 0.477
Mouse
chromatin organization GO:0006325 206 0.476
cellular amide metabolic process GO:0043603 58 0.472
carbohydrate biosynthetic process GO:0016051 74 0.468
Mouse
regulation of cellular catabolic process GO:0031329 242 0.463
genetic imprinting GO:0071514 27 0.459
trigeminal sensory nucleus development GO:0021730 2 0.458
mammary gland duct morphogenesis GO:0060603 38 0.454
regulation of protein binding GO:0043393 60 0.453
establishment of protein localization to organelle GO:0072594 118 0.452
angiogenesis GO:0001525 201 0.446
positive regulation of apoptotic process GO:0043065 217 0.441
Mouse
rhodopsin mediated signaling pathway GO:0016056 4 0.431
lung ciliated cell differentiation GO:0061141 1 0.426
regulation of lipid catabolic process GO:0050994 15 0.425
regulation of osteoblast differentiation GO:0045667 67 0.424
phototransduction GO:0007602 17 0.424
regulation of cellular amine metabolic process GO:0033238 20 0.420
regulation of defense response GO:0031347 233 0.417
Mouse
circadian temperature homeostasis GO:0060086 2 0.414
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.405
Mouse
cellular response to inorganic substance GO:0071241 37 0.405
cellular response to hormone stimulus GO:0032870 150 0.404
mammary gland epithelium development GO:0061180 65 0.402
lipid localization GO:0010876 126 0.390
regulation of glucose metabolic process GO:0010906 60 0.389
morphogenesis of a branching epithelium GO:0061138 193 0.386
eye photoreceptor cell differentiation GO:0001754 41 0.385
macromolecule methylation GO:0043414 120 0.381
regulation of protein localization to nucleus GO:1900180 60 0.375
lung cell differentiation GO:0060479 30 0.374
g protein coupled receptor signaling pathway GO:0007186 243 0.366
methylation GO:0032259 134 0.366
response to extracellular stimulus GO:0009991 127 0.366
Rat
regulation of lipid transport GO:0032368 36 0.365
positive regulation of striated muscle cell differentiation GO:0051155 35 0.362
regulation of nucleocytoplasmic transport GO:0046822 73 0.361
lung development GO:0030324 164 0.359
circulatory system process GO:0003013 197 0.357
response to ph GO:0009268 14 0.356
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.352
Rat
regulation of carbohydrate metabolic process GO:0006109 75 0.349
regulation of fatty acid oxidation GO:0046320 10 0.349
response to inactivity GO:0014854 4 0.347
carbohydrate derivative biosynthetic process GO:1901137 183 0.346
regulation of mapk cascade GO:0043408 248 0.345
regulation of translation GO:0006417 71 0.341
Mouse
lung epithelial cell differentiation GO:0060487 29 0.337
chromatin modification GO:0016568 187 0.328
positive regulation of cellular amine metabolic process GO:0033240 5 0.328
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.324
forebrain generation of neurons GO:0021872 63 0.322
regulation of multi organism process GO:0043900 111 0.322
regulation of camp metabolic process GO:0030814 30 0.321
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.319
Mouse
regulation of myeloid cell differentiation GO:0045637 96 0.317
Mouse
protein localization to nucleus GO:0034504 121 0.315
regulation of osteoclast differentiation GO:0045670 36 0.312
thyroid hormone mediated signaling pathway GO:0002154 3 0.312
monosaccharide metabolic process GO:0005996 106 0.311
positive regulation of cell death GO:0010942 224 0.310
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.306
muscle cell differentiation GO:0042692 261 0.304
cd4 positive alpha beta t cell activation GO:0035710 45 0.303
regulation of carbohydrate biosynthetic process GO:0043255 40 0.301
nucleocytoplasmic transport GO:0006913 139 0.298
bone mineralization GO:0030282 54 0.297
hexose metabolic process GO:0019318 98 0.297
lipid homeostasis GO:0055088 63 0.296
Mouse
dna metabolic process GO:0006259 303 0.293
regulation of pigment cell differentiation GO:0050932 7 0.293
respiratory tube development GO:0030323 167 0.292
dopamine receptor signaling pathway GO:0007212 16 0.291
hindlimb morphogenesis GO:0035137 42 0.285
Mouse
energy homeostasis GO:0097009 15 0.284
Mouse
translation GO:0006412 93 0.283
Mouse
regulation of steroid biosynthetic process GO:0050810 26 0.282
Mouse
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.280
single organism nuclear import GO:1902593 95 0.279
carbohydrate catabolic process GO:0016052 32 0.277
macromolecule deacylation GO:0098732 37 0.274
regulation of histone modification GO:0031056 56 0.274
circadian rhythm GO:0007623 114 0.270
Mouse
replacement ossification GO:0036075 26 0.269
regulation of fatty acid metabolic process GO:0019217 28 0.269
negative regulation of cell proliferation GO:0008285 296 0.267
Mouse
embryonic skeletal system morphogenesis GO:0048704 91 0.266
diencephalon development GO:0021536 63 0.264
protein import into nucleus GO:0006606 95 0.263
glycogen metabolic process GO:0005977 32 0.262
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.261
regulation of lipid metabolic process GO:0019216 118 0.259
response to temperature stimulus GO:0009266 55 0.258
histone modification GO:0016570 159 0.258
polysaccharide metabolic process GO:0005976 39 0.257
Mouse
negative regulation of protein localization to nucleus GO:1900181 23 0.256
kidney development GO:0001822 213 0.255
Mouse Rat
cytoplasmic sequestering of transcription factor GO:0042994 5 0.251
cellular chemical homeostasis GO:0055082 215 0.250
Mouse
formation of radial glial scaffolds GO:0021943 4 0.247
cellular response to radiation GO:0071478 28 0.245
positive regulation of muscle cell differentiation GO:0051149 39 0.244
glucose homeostasis GO:0042593 128 0.242
Mouse
negative regulation of fat cell differentiation GO:0045599 36 0.242
regulation of membrane potential GO:0042391 192 0.242
myeloid cell differentiation GO:0030099 233 0.239
regulation of chromatin modification GO:1903308 57 0.239
hormone metabolic process GO:0042445 86 0.238
ras protein signal transduction GO:0007265 77 0.235
myeloid cell apoptotic process GO:0033028 22 0.235
cellular response to cytokine stimulus GO:0071345 189 0.234
positive regulation of cell cycle GO:0045787 92 0.232
rhythmic process GO:0048511 174 0.231
Mouse
cerebellar granular layer development GO:0021681 13 0.230
regulation of protein import into nucleus translocation GO:0033158 2 0.229
regulation of secretion GO:0051046 274 0.227
Mouse
phenol containing compound metabolic process GO:0018958 60 0.224
regulation of cellular response to stress GO:0080135 159 0.223
response to inorganic substance GO:0010035 96 0.223
purine containing compound biosynthetic process GO:0072522 70 0.221
heart morphogenesis GO:0003007 178 0.219
Mouse
positive regulation of peptide hormone secretion GO:0090277 31 0.218
type ii pneumocyte differentiation GO:0060510 7 0.218
insulin secretion GO:0030073 89 0.217
Mouse
hypophysis morphogenesis GO:0048850 3 0.215
cyclic nucleotide metabolic process GO:0009187 59 0.215
embryonic placenta development GO:0001892 98 0.214
cardiac chamber morphogenesis GO:0003206 93 0.213
Mouse
cellular lipid metabolic process GO:0044255 323 0.212
canonical wnt signaling pathway GO:0060070 130 0.211
response to monosaccharide GO:0034284 67 0.211
Mouse
multicellular organismal homeostasis GO:0048871 164 0.211
Mouse
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 18 0.210
carbohydrate homeostasis GO:0033500 128 0.210
Mouse
sensory perception GO:0007600 245 0.209
Mouse
camera type eye photoreceptor cell differentiation GO:0060219 15 0.208
cellular response to abiotic stimulus GO:0071214 56 0.207
positive regulation of osteoblast differentiation GO:0045669 34 0.207
cellular homeostasis GO:0019725 240 0.207
Mouse
pituitary gland development GO:0021983 38 0.204
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.203
positive regulation of osteoclast differentiation GO:0045672 15 0.202
posttranscriptional regulation of gene expression GO:0010608 155 0.202
Mouse
cellular ketone metabolic process GO:0042180 84 0.198
Mouse
nuclear transport GO:0051169 139 0.196
positive regulation of cytoplasmic transport GO:1903651 40 0.195
developmental growth involved in morphogenesis GO:0060560 138 0.195
Mouse
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.195
cellular response to biotic stimulus GO:0071216 92 0.194
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.194
sulfur compound biosynthetic process GO:0044272 37 0.193
urogenital system development GO:0001655 261 0.193
Mouse Rat
hexose biosynthetic process GO:0019319 39 0.192
positive regulation of binding GO:0051099 49 0.192
glycerolipid metabolic process GO:0046486 122 0.190
cellular glucose homeostasis GO:0001678 52 0.187
Mouse
face development GO:0060324 38 0.187
Mouse
cell maturation GO:0048469 127 0.185
cartilage development GO:0051216 140 0.185
regulation of organ morphogenesis GO:2000027 144 0.184
embryonic appendage morphogenesis GO:0035113 126 0.184
Mouse
lipid transport GO:0006869 98 0.182
regulation of striated muscle cell differentiation GO:0051153 81 0.182
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.180
Mouse
cellular amine metabolic process GO:0044106 44 0.180
response to organonitrogen compound GO:0010243 246 0.180
phosphatidylinositol mediated signaling GO:0048015 41 0.180
regulation of melanocyte differentiation GO:0045634 7 0.179
anatomical structure homeostasis GO:0060249 145 0.179
regulation of lyase activity GO:0051339 13 0.177
neurotransmitter secretion GO:0007269 62 0.176
nucleotide biosynthetic process GO:0009165 78 0.176
regulation of androgen receptor signaling pathway GO:0060765 3 0.175
central nervous system neuron differentiation GO:0021953 162 0.174
carboxylic acid catabolic process GO:0046395 51 0.171
polysaccharide biosynthetic process GO:0000271 20 0.169
Mouse
organophosphate biosynthetic process GO:0090407 122 0.169
regulation of innate immune response GO:0045088 91 0.166
defense response to other organism GO:0098542 197 0.166
adenylate cyclase activating dopamine receptor signaling pathway GO:0007191 7 0.165
branching morphogenesis of an epithelial tube GO:0048754 159 0.164
carbon catabolite activation of transcription GO:0045991 4 0.162
body morphogenesis GO:0010171 45 0.161
anterior commissure morphogenesis GO:0021960 6 0.161
acetate ester transport GO:1901374 2 0.161
reactive oxygen species metabolic process GO:0072593 84 0.159
negative regulation of molecular function GO:0044092 258 0.158
Rat
negative regulation of intracellular protein transport GO:0090317 27 0.158
cellular amino acid catabolic process GO:0009063 25 0.158
retina morphogenesis in camera type eye GO:0060042 45 0.157
heart process GO:0003015 94 0.156
negative regulation of phosphate metabolic process GO:0045936 184 0.156
intracellular receptor signaling pathway GO:0030522 74 0.155
nuclear import GO:0051170 95 0.155
cation homeostasis GO:0055080 212 0.153
lipid catabolic process GO:0016042 69 0.152
cellular response to carbohydrate stimulus GO:0071322 50 0.152
Mouse
prostate gland development GO:0030850 48 0.151
Mouse
positive regulation of lipid metabolic process GO:0045834 40 0.150
Mouse
regulation of stem cell proliferation GO:0072091 78 0.149
prostate glandular acinus development GO:0060525 12 0.148
mapk cascade GO:0000165 281 0.147
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.147
positive regulation of cell development GO:0010720 237 0.146
positive regulation of phospholipase c activity GO:0010863 2 0.144
epithelial cell proliferation GO:0050673 174 0.144
glycolytic process GO:0006096 20 0.144
organic hydroxy compound catabolic process GO:1901616 25 0.144
skin development GO:0043588 220 0.144
reactive oxygen species biosynthetic process GO:1903409 8 0.143
amine metabolic process GO:0009308 45 0.140
protein targeting GO:0006605 143 0.140
cerebellar purkinje cell layer development GO:0021680 26 0.139
courtship behavior GO:0007619 5 0.137
wnt signaling pathway GO:0016055 188 0.137
cyclic nucleotide biosynthetic process GO:0009190 44 0.136
maintenance of location GO:0051235 89 0.136
ventricular cardiac muscle cell differentiation GO:0055012 17 0.136
Mouse
creatinine metabolic process GO:0046449 3 0.134
covalent chromatin modification GO:0016569 163 0.134
regulation of intracellular protein transport GO:0033157 82 0.134
monosaccharide biosynthetic process GO:0046364 44 0.133
cytoplasmic transport GO:0016482 234 0.133
tube formation GO:0035148 140 0.132
Mouse
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.131
sensory perception of smell GO:0007608 26 0.130
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.129
regulation of cell migration GO:0030334 219 0.129
regulation of cell motility GO:2000145 236 0.129
regulation of lipid biosynthetic process GO:0046890 54 0.127
Mouse
regulation of cytoplasmic transport GO:1903649 112 0.127
regulation of establishment of protein localization GO:0070201 181 0.125
regulation of lipid kinase activity GO:0043550 14 0.125
chondroblast differentiation GO:0060591 2 0.124
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.124
multi multicellular organism process GO:0044706 109 0.123
principal sensory nucleus of trigeminal nerve development GO:0021740 2 0.122
regulation of inflammatory response GO:0050727 147 0.121
Mouse
regulation of kinase activity GO:0043549 249 0.120
respiratory system development GO:0060541 190 0.118
developmental cell growth GO:0048588 84 0.118
Mouse
activation of janus kinase activity GO:0042976 2 0.117
germ line stem cell division GO:0042078 2 0.116
regulation of morphogenesis of a branching structure GO:0060688 53 0.115
neural precursor cell proliferation GO:0061351 121 0.115
regulation of cholesterol metabolic process GO:0090181 14 0.113
positive regulation of hormone metabolic process GO:0032352 3 0.112
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.111
axon guidance GO:0007411 141 0.111
hindbrain development GO:0030902 128 0.111
regulation of granulocyte differentiation GO:0030852 8 0.111
Mouse
positive regulation of carbohydrate metabolic process GO:0045913 30 0.111
embryonic skeletal system development GO:0048706 120 0.108
cardiac chamber development GO:0003205 108 0.107
Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.106
fertilization GO:0009566 127 0.106
morphogenesis of embryonic epithelium GO:0016331 159 0.106
Mouse
inflammatory response GO:0006954 244 0.106
Mouse
response to iron ion GO:0010039 4 0.106
regulation of thyroid hormone mediated signaling pathway GO:0002155 3 0.105
dna methylation GO:0006306 43 0.105
regulation of peptide transport GO:0090087 91 0.105
Mouse
regulation of fatty acid beta oxidation GO:0031998 1 0.104
biomineral tissue development GO:0031214 64 0.103
ureteric bud development GO:0001657 94 0.103
Mouse
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.102
Mouse
odontogenesis of dentin containing tooth GO:0042475 66 0.101
nucleoside phosphate biosynthetic process GO:1901293 79 0.101
cerebellum morphogenesis GO:0021587 42 0.101
multicellular organismal reproductive behavior GO:0033057 23 0.101
stress activated mapk cascade GO:0051403 80 0.100
purine nucleotide biosynthetic process GO:0006164 65 0.099
sensory organ morphogenesis GO:0090596 242 0.099
Mouse
peptide secretion GO:0002790 114 0.099
Mouse
regulation of p38mapk cascade GO:1900744 3 0.097
negative regulation of calcium ion transmembrane transporter activity GO:1901020 1 0.097
regulation of steroid hormone biosynthetic process GO:0090030 4 0.097
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.096
ribonucleotide biosynthetic process GO:0009260 59 0.095
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis GO:0060527 7 0.095
regulation of chromosome organization GO:0033044 83 0.095
positive regulation of defense response GO:0031349 124 0.095
striated muscle hypertrophy GO:0014897 24 0.094
endocrine system development GO:0035270 98 0.094
negative regulation of lyase activity GO:0051350 1 0.094
sensory perception of chemical stimulus GO:0007606 51 0.094
camp biosynthetic process GO:0006171 31 0.093
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.092
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.092
regulation of protein transport GO:0051223 163 0.092
regulation of generation of precursor metabolites and energy GO:0043467 38 0.092
embryonic digit morphogenesis GO:0042733 56 0.091
dna alkylation GO:0006305 43 0.091
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.090
cellular response to molecule of bacterial origin GO:0071219 83 0.090
Mouse
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.089
carbon catabolite regulation of transcription GO:0045990 4 0.089
regulation of hormone metabolic process GO:0032350 15 0.088
positive regulation of fatty acid beta oxidation GO:0032000 1 0.088
hydrogen peroxide metabolic process GO:0042743 16 0.088
positive regulation of phospholipase activity GO:0010518 3 0.088
neural tube formation GO:0001841 108 0.088
Mouse
regulation of reproductive process GO:2000241 66 0.088
mammary gland morphogenesis GO:0060443 54 0.088
response to peptide hormone GO:0043434 127 0.087
regulation of ossification GO:0030278 112 0.087
hormone secretion GO:0046879 128 0.086
Mouse
placenta development GO:0001890 140 0.086
positive regulation of transcription by galactose GO:0000411 1 0.086
amide transport GO:0042886 138 0.086
Mouse
regulation of glutamine family amino acid metabolic process GO:0000820 1 0.086
alpha beta t cell differentiation GO:0046632 69 0.085
positive regulation of apoptotic signaling pathway GO:2001235 95 0.085
embryonic organ morphogenesis GO:0048562 276 0.085
Mouse
endochondral bone growth GO:0003416 19 0.085
Mouse
histone acetylation GO:0016573 41 0.084
positive regulation of programmed cell death GO:0043068 218 0.083
Mouse
cellular response to glucose stimulus GO:0071333 45 0.082
Mouse
fat soluble vitamin metabolic process GO:0006775 11 0.082
positive regulation of protein export from nucleus GO:0046827 4 0.082
cellular response to external stimulus GO:0071496 88 0.082
protein kinase b signaling GO:0043491 74 0.081
cellular response to extracellular stimulus GO:0031668 81 0.081
intracellular protein transport GO:0006886 204 0.081
pyruvate metabolic process GO:0006090 28 0.080
wnt signaling pathway involved in kidney development GO:0061289 2 0.079
blood vessel morphogenesis GO:0048514 285 0.079
positive regulation of stem cell proliferation GO:2000648 59 0.079
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.079
definitive erythrocyte differentiation GO:0060318 7 0.078
ear development GO:0043583 200 0.078
serotonin receptor signaling pathway GO:0007210 8 0.078
engulfment of apoptotic cell GO:0043652 3 0.078
regulation of neuron differentiation GO:0045664 281 0.077
locomotory behavior GO:0007626 195 0.077
phospholipid metabolic process GO:0006644 87 0.076
regulation of secretion by cell GO:1903530 249 0.075
Mouse
negative regulation of cytoplasmic transport GO:1903650 29 0.075
negative regulation of binding GO:0051100 39 0.074
regulation of erk1 and erk2 cascade GO:0070372 71 0.074
triglyceride homeostasis GO:0070328 15 0.072
positive regulation of ossification GO:0045778 47 0.072
negative regulation of growth of symbiont in host GO:0044130 19 0.072
cerebellar cortex formation GO:0021697 22 0.071
dna modification GO:0006304 50 0.071
purine ribonucleotide metabolic process GO:0009150 290 0.070
ribose phosphate biosynthetic process GO:0046390 59 0.070
purine ribonucleotide biosynthetic process GO:0009152 59 0.070
ovarian follicle development GO:0001541 40 0.070
stem cell maintenance GO:0019827 130 0.069
positive regulation of chromatin modification GO:1903310 28 0.069
response to organic cyclic compound GO:0014070 198 0.069
response to peptide GO:1901652 136 0.069
stem cell proliferation GO:0072089 117 0.069
response to nitric oxide GO:0071731 4 0.068
regulation of muscle tissue development GO:1901861 97 0.067
Mouse
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.067
positive regulation of chromosome organization GO:2001252 33 0.067
gluconeogenesis GO:0006094 39 0.067
innate immune response GO:0045087 157 0.067
adult behavior GO:0030534 135 0.067
response to amphetamine GO:0001975 16 0.066
positive regulation of myeloid cell differentiation GO:0045639 43 0.066
skeletal muscle cell differentiation GO:0035914 66 0.066
Mouse
regulation of cellular protein catabolic process GO:1903362 61 0.066
organic acid transport GO:0015849 101 0.066
ensheathment of neurons GO:0007272 76 0.066
regulation of camp biosynthetic process GO:0030817 25 0.065
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.065
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.065
plasma membrane long chain fatty acid transport GO:0015911 1 0.065
regulation of skeletal muscle cell differentiation GO:2001014 11 0.065
Mouse
chondrocyte differentiation GO:0002062 72 0.064
Mouse
positive regulation of leukocyte differentiation GO:1902107 86 0.064
positive regulation of cell migration GO:0030335 109 0.064
neural tube development GO:0021915 160 0.064
Mouse
action potential GO:0001508 78 0.064
regulation of protein kinase b signaling GO:0051896 56 0.063
regulation of nucleotide biosynthetic process GO:0030808 34 0.063
positive regulation of female receptivity GO:0045925 3 0.062
cell growth GO:0016049 130 0.062
Mouse
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.060
b cell activation GO:0042113 161 0.060
protein deacetylation GO:0006476 32 0.060
cartilage condensation GO:0001502 18 0.060
positive regulation of gluconeogenesis GO:0045722 11 0.060
odontogenesis GO:0042476 78 0.060
regulation of insulin receptor signaling pathway GO:0046626 21 0.060
regulation of developmental pigmentation GO:0048070 14 0.060
growth plate cartilage chondrocyte growth GO:0003430 2 0.059
Mouse
regulation of gluconeogenesis GO:0006111 30 0.059
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.059
neuron death GO:0070997 154 0.058
organonitrogen compound biosynthetic process GO:1901566 192 0.058

Thra disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
thyroid gland disease DOID:50 0 0.649
Human
hypothyroidism DOID:1459 0 0.649
Human
disease of anatomical entity DOID:7 0 0.649
Human
endocrine system disease DOID:28 0 0.649
Human
diabetes mellitus DOID:9351 0 0.414
type 2 diabetes mellitus DOID:9352 0 0.414
disease of metabolism DOID:0014667 0 0.414
carbohydrate metabolism disease DOID:0050013 0 0.414
glucose metabolism disease DOID:4194 0 0.414
acquired metabolic disease DOID:0060158 0 0.414
central nervous system disease DOID:331 0 0.093
nervous system disease DOID:863 0 0.093