Mus musculus

60 known processes

Ticam2

toll-like receptor adaptor molecule 2

(Aliases: B430113A10,TICAM-2,TRAM,Trif,MGC107370,Tirp)

Ticam2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
detection of molecule of bacterial origin GO:0032490 2 0.535
cellular response to peptidoglycan GO:0071224 4 0.502
regulation of nucleotide binding oligomerization domain containing 1 signaling pathway GO:0070428 3 0.185
interferon beta biosynthetic process GO:0045350 4 0.158
Zebrafish Mouse
response to molecule of fungal origin GO:0002238 4 0.151
defense response to other organism GO:0098542 197 0.145
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.116
Mouse
regulation of cell activation GO:0050865 289 0.107
Mouse
positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway GO:0070434 2 0.105
monocarboxylic acid metabolic process GO:0032787 191 0.102
activation of immune response GO:0002253 138 0.101
Mouse
induction by organism of immune response of other organism involved in symbiotic interaction GO:0052558 1 0.099
response to organonitrogen compound GO:0010243 246 0.092
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.090
cytokine production GO:0001816 319 0.080
cellular response to biotic stimulus GO:0071216 92 0.079
Mouse
negative regulation of immune system process GO:0002683 209 0.079
response to molecule of bacterial origin GO:0002237 143 0.077
Mouse
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.075
reactive oxygen species biosynthetic process GO:1903409 8 0.074
response to bacterial lipoprotein GO:0032493 4 0.074
inflammatory response GO:0006954 244 0.070
response to lipopolysaccharide GO:0032496 128 0.070
Mouse
cellular response to lipid GO:0071396 145 0.068
Mouse
nitrogen compound transport GO:0071705 271 0.066
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.062
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.062
cellular lipid metabolic process GO:0044255 323 0.062
t cell activation GO:0042110 289 0.060
leukocyte differentiation GO:0002521 342 0.060
cellular amino acid metabolic process GO:0006520 103 0.060
response to defense related nitric oxide production by other organism involved in symbiotic interaction GO:0052551 2 0.060
carbohydrate metabolic process GO:0005975 230 0.059
leukocyte proliferation GO:0070661 172 0.059
Mouse
myeloid leukocyte activation GO:0002274 83 0.058
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.058
detection of stimulus GO:0051606 84 0.057
cellular response to lipopolysaccharide GO:0071222 77 0.056
Mouse
i kappab kinase nf kappab signaling GO:0007249 85 0.056
Zebrafish Mouse
multicellular organismal homeostasis GO:0048871 164 0.056
reactive oxygen species metabolic process GO:0072593 84 0.056
positive regulation of cytokine production GO:0001819 174 0.055
b cell activation GO:0042113 161 0.054
Mouse
male gamete generation GO:0048232 285 0.052
leukocyte migration GO:0050900 124 0.051
immune effector process GO:0002252 321 0.051
Mouse
regulation of b cell proliferation GO:0030888 39 0.050
Mouse
regulation of cytokine production GO:0001817 266 0.050
dna metabolic process GO:0006259 303 0.050
positive regulation of cell activation GO:0050867 158 0.049
Mouse
chemotaxis GO:0006935 247 0.049
lymphocyte mediated immunity GO:0002449 139 0.048
regulation of body fluid levels GO:0050878 162 0.048
regulation of lymphocyte activation GO:0051249 240 0.048
Mouse
production of molecular mediator involved in inflammatory response GO:0002532 21 0.047
adaptive immune response GO:0002250 155 0.047
regulation of membrane potential GO:0042391 192 0.046
regulation of interleukin 6 production GO:0032675 55 0.046
leukocyte activation involved in immune response GO:0002366 126 0.046
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.045
regulation of inflammatory response GO:0050727 147 0.045
purine ribonucleotide metabolic process GO:0009150 290 0.045
regulation of defense response GO:0031347 233 0.045
Mouse
regulation of secretion GO:0051046 274 0.045
regulation of secretion by cell GO:1903530 249 0.045
cellular ketone metabolic process GO:0042180 84 0.045
transmembrane transport GO:0055085 412 0.044
protein modification by small protein conjugation or removal GO:0070647 207 0.043
Mouse
mapk cascade GO:0000165 281 0.043
cellular amine metabolic process GO:0044106 44 0.042
spermatogenesis GO:0007283 284 0.042
nucleotide binding oligomerization domain containing 1 signaling pathway GO:0070427 5 0.042
regulation of cell motility GO:2000145 236 0.041
neuronal action potential GO:0019228 54 0.041
developmental maturation GO:0021700 193 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.040
cell adhesion GO:0007155 329 0.040
cell type specific apoptotic process GO:0097285 268 0.040
homeostasis of number of cells GO:0048872 210 0.040
lymphocyte homeostasis GO:0002260 64 0.040
toxin transport GO:1901998 38 0.039
positive regulation of apoptotic process GO:0043065 217 0.039
hemostasis GO:0007599 78 0.039
regulation of innate immune response GO:0045088 91 0.039
Mouse
immune response regulating signaling pathway GO:0002764 125 0.039
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.038
innate immune response GO:0045087 157 0.038
Mouse
response to acid chemical GO:0001101 111 0.037
interleukin 18 production GO:0032621 4 0.037
regulation of system process GO:0044057 200 0.037
lymphocyte apoptotic process GO:0070227 54 0.037
production of molecular mediator of immune response GO:0002440 103 0.037
apoptotic signaling pathway GO:0097190 306 0.037
Mouse
leukocyte mediated immunity GO:0002443 174 0.037
protein processing GO:0016485 163 0.037
positive regulation of innate immune response GO:0045089 80 0.037
Mouse
negative regulation of t cell activation GO:0050868 65 0.037
positive regulation of lymphocyte activation GO:0051251 140 0.037
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.037
cellular response to lipoteichoic acid GO:0071223 6 0.037
lymphocyte differentiation GO:0030098 242 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.036
regulation of cell cycle GO:0051726 281 0.036
organic hydroxy compound metabolic process GO:1901615 203 0.036
renal system development GO:0072001 225 0.036
nitric oxide synthase biosynthetic process GO:0051767 7 0.035
cell maturation GO:0048469 127 0.035
blood vessel morphogenesis GO:0048514 285 0.035
defense response to bacterium GO:0042742 119 0.035
immune response activating signal transduction GO:0002757 116 0.035
Mouse
fatty acid metabolic process GO:0006631 121 0.035
macrophage activation GO:0042116 27 0.035
Mouse
regulation of homeostatic process GO:0032844 182 0.035
regulation of cellular amine metabolic process GO:0033238 20 0.034
interleukin 17 production GO:0032620 11 0.034
lymphocyte activation involved in immune response GO:0002285 93 0.034
protein maturation GO:0051604 176 0.034
regulation of reactive oxygen species metabolic process GO:2000377 40 0.034
interleukin 8 production GO:0032637 4 0.034
sensory perception GO:0007600 245 0.033
regulation of cellular ketone metabolic process GO:0010565 66 0.033
amine metabolic process GO:0009308 45 0.032
positive regulation of b cell activation GO:0050871 49 0.032
Mouse
transmission of nerve impulse GO:0019226 76 0.032
cation transmembrane transport GO:0098655 266 0.032
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.032
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.032
defense response to virus GO:0051607 68 0.032
Mouse
positive regulation of secretion GO:0051047 130 0.032
metal ion homeostasis GO:0055065 189 0.032
germ cell development GO:0007281 185 0.032
cellular macromolecule catabolic process GO:0044265 206 0.032
cellular response to acid chemical GO:0071229 68 0.031
regulation of establishment of protein localization GO:0070201 181 0.031
organic acid transport GO:0015849 101 0.031
lymphocyte proliferation GO:0046651 164 0.031
Mouse
camera type eye development GO:0043010 266 0.031
regulation of cell migration GO:0030334 219 0.031
g protein coupled receptor signaling pathway GO:0007186 243 0.031
action potential GO:0001508 78 0.030
regulation of protein localization GO:0032880 231 0.030
macromolecule catabolic process GO:0009057 281 0.030
intrinsic apoptotic signaling pathway GO:0097193 132 0.030
positive regulation of leukocyte mediated immunity GO:0002705 70 0.030
muscle system process GO:0003012 141 0.030
positive regulation of lipopolysaccharide mediated signaling pathway GO:0031666 5 0.030
regulation of cellular catabolic process GO:0031329 242 0.029
aromatic compound catabolic process GO:0019439 286 0.029
response to host defenses GO:0052200 3 0.029
sensory organ morphogenesis GO:0090596 242 0.029
regulation of response to wounding GO:1903034 189 0.029
regulation of interleukin 18 production GO:0032661 3 0.028
regulation of interleukin 8 production GO:0032677 3 0.028
urogenital system development GO:0001655 261 0.028
epithelial tube morphogenesis GO:0060562 303 0.028
negative regulation of cell development GO:0010721 169 0.028
b cell proliferation GO:0042100 53 0.028
Mouse
membrane organization GO:0061024 245 0.028
response to lipoteichoic acid GO:0070391 6 0.028
response to peptide GO:1901652 136 0.027
regulation of lymphocyte proliferation GO:0050670 117 0.027
Mouse
skeletal system development GO:0001501 356 0.027
coagulation GO:0050817 78 0.027
hematopoietic progenitor cell differentiation GO:0002244 143 0.027
regulation of hormone levels GO:0010817 211 0.027
myeloid leukocyte differentiation GO:0002573 119 0.027
response to peptidoglycan GO:0032494 9 0.026
regulation of protein transport GO:0051223 163 0.026
antibiotic transport GO:0042891 1 0.026
cell fate commitment GO:0045165 210 0.026
microglial cell activation GO:0001774 3 0.026
modulation by symbiont of defense related host nitric oxide production GO:0052163 1 0.026
ossification GO:0001503 216 0.026
regulation of interferon beta biosynthetic process GO:0045357 4 0.026
Zebrafish Mouse
detection of lipopolysaccharide GO:0032497 1 0.026
cellular response to oxidative stress GO:0034599 76 0.026
protein secretion GO:0009306 111 0.026
regulation of apoptotic signaling pathway GO:2001233 197 0.025
regulation of mapk cascade GO:0043408 248 0.025
defense response to gram positive bacterium GO:0050830 50 0.025
purine containing compound metabolic process GO:0072521 311 0.025
induction by organism of defense related nitric oxide production in other organism involved in symbiotic interaction GO:0052263 1 0.025
positive regulation of macrophage cytokine production GO:0060907 7 0.025
forebrain development GO:0030900 302 0.025
positive regulation by symbiont of defense related host nitric oxide production GO:0052347 1 0.025
positive regulation of binding GO:0051099 49 0.025
Mouse
engulfment of apoptotic cell GO:0043652 3 0.025
organic anion transport GO:0015711 137 0.025
carboxylic acid biosynthetic process GO:0046394 86 0.025
regulation of interferon gamma production GO:0032649 57 0.025
response to immune response of other organism involved in symbiotic interaction GO:0052564 3 0.025
leukocyte apoptotic process GO:0071887 71 0.025
negative regulation of cell proliferation GO:0008285 296 0.025
induction by symbiont of host immune response GO:0052559 1 0.025
cation transport GO:0006812 399 0.024
toll like receptor signaling pathway GO:0002224 38 0.024
Mouse
regulation of cytokine biosynthetic process GO:0042035 59 0.024
Zebrafish Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.024
unsaturated fatty acid metabolic process GO:0033559 31 0.024
tissue homeostasis GO:0001894 115 0.024
negative regulation of phosphate metabolic process GO:0045936 184 0.024
wound healing GO:0042060 157 0.024
regulation of response to biotic stimulus GO:0002831 38 0.023
positive regulation of apoptotic signaling pathway GO:2001235 95 0.023
nucleoside phosphate metabolic process GO:0006753 338 0.023
positive regulation of protein transport GO:0051222 93 0.023
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.023
Mouse
response to defense related host nitric oxide production GO:0052565 2 0.023
positive regulation of lymphocyte proliferation GO:0050671 70 0.023
Mouse
epidermis development GO:0008544 187 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
positive regulation of cell migration GO:0030335 109 0.023
positive regulation of protein modification process GO:0031401 299 0.023
Mouse
carboxylic acid transport GO:0046942 100 0.023
positive regulation of interleukin 8 production GO:0032757 2 0.022
negative regulation of growth GO:0045926 99 0.022
purine nucleotide metabolic process GO:0006163 302 0.022
angiogenesis GO:0001525 201 0.022
pattern recognition receptor signaling pathway GO:0002221 47 0.022
Mouse
regulation of multi organism process GO:0043900 111 0.022
skin development GO:0043588 220 0.022
modification by symbiont of host morphology or physiology GO:0044003 4 0.022
glial cell differentiation GO:0010001 131 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
natural killer cell activation GO:0030101 44 0.022
Mouse
posttranscriptional regulation of gene expression GO:0010608 155 0.022
regulation of cellular response to stress GO:0080135 159 0.021
cellular homeostasis GO:0019725 240 0.021
ion transmembrane transport GO:0034220 361 0.021
organic cyclic compound catabolic process GO:1901361 295 0.021
regulation of organelle organization GO:0033043 289 0.021
regulation of nucleotide binding oligomerization domain containing signaling pathway GO:0070424 3 0.021
positive regulation of antimicrobial peptide production GO:0002225 1 0.021
nucleotide metabolic process GO:0009117 332 0.021
response to oxidative stress GO:0006979 123 0.021
positive regulation of nervous system development GO:0051962 221 0.021
gland development GO:0048732 330 0.021
cellular response to cytokine stimulus GO:0071345 189 0.021
cytokine secretion GO:0050663 72 0.021
neural tube development GO:0021915 160 0.020
regulation of leukocyte proliferation GO:0070663 121 0.020
Mouse
cellular chemical homeostasis GO:0055082 215 0.020
regulation of neuron apoptotic process GO:0043523 122 0.020
protein modification by small protein conjugation GO:0032446 187 0.020
Mouse
extracellular matrix organization GO:0030198 147 0.020
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.020
cytokine mediated signaling pathway GO:0019221 115 0.020
regulation of tumor necrosis factor production GO:0032680 49 0.020
Mouse
interferon gamma production GO:0032609 67 0.020
wnt signaling pathway GO:0016055 188 0.020
amide transport GO:0042886 138 0.020
positive regulation by symbiont of host defense response GO:0052509 1 0.020
dna recombination GO:0006310 92 0.020
response to organic cyclic compound GO:0014070 198 0.020
Mouse
tube formation GO:0035148 140 0.020
peptidyl amino acid modification GO:0018193 336 0.020
inorganic ion transmembrane transport GO:0098660 234 0.020
organ growth GO:0035265 117 0.020
regulation of cytoplasmic transport GO:1903649 112 0.020
b cell activation involved in immune response GO:0002312 50 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
detection of chemical stimulus GO:0009593 16 0.019
axon ensheathment GO:0008366 76 0.019
nuclear division GO:0000280 158 0.019
muscle tissue development GO:0060537 308 0.019
protein catabolic process GO:0030163 221 0.019
positive regulation of tumor necrosis factor production GO:0032760 30 0.019
Mouse
response to inorganic substance GO:0010035 96 0.019
regulation of protein secretion GO:0050708 82 0.019
somatic diversification of immune receptors GO:0002200 53 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
peptide transport GO:0015833 133 0.019
cellular carbohydrate metabolic process GO:0044262 119 0.019
cellular response to peptide GO:1901653 92 0.019
positive regulation of proteolysis GO:0045862 85 0.019
positive regulation of leukocyte proliferation GO:0070665 73 0.019
Mouse
cation homeostasis GO:0055080 212 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
intestinal epithelial structure maintenance GO:0060729 4 0.019
interleukin 23 production GO:0032627 2 0.019
glycoprotein metabolic process GO:0009100 116 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
positive regulation of immune effector process GO:0002699 107 0.019
regulation of anatomical structure size GO:0090066 178 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
negative regulation of nervous system development GO:0051961 156 0.019
response to interleukin 12 GO:0070671 2 0.019
myeloid cell differentiation GO:0030099 233 0.018
positive regulation of protein secretion GO:0050714 52 0.018
anion transport GO:0006820 177 0.018
cellular ion homeostasis GO:0006873 165 0.018
fat cell differentiation GO:0045444 160 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
regulation of lipopolysaccharide mediated signaling pathway GO:0031664 9 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
response to insulin GO:0032868 100 0.018
blood circulation GO:0008015 195 0.018
response to peptide hormone GO:0043434 127 0.018
leukotriene metabolic process GO:0006691 7 0.018
cell recognition GO:0008037 83 0.018
sulfur compound metabolic process GO:0006790 100 0.018
cellular response to bacterial lipoprotein GO:0071220 3 0.018
regulation of cytokine secretion GO:0050707 61 0.018
regulation of exit from mitosis GO:0007096 1 0.018
myelination GO:0042552 74 0.018
negative regulation of lymphocyte activation GO:0051250 91 0.018
positive regulation of interleukin 6 production GO:0032755 37 0.018
endocytosis GO:0006897 168 0.018
positive regulation of hemostasis GO:1900048 10 0.018
regulation of ossification GO:0030278 112 0.018
neuron migration GO:0001764 122 0.018
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.018
spermatid development GO:0007286 108 0.017
central nervous system neuron differentiation GO:0021953 162 0.017
regulation of nucleotide binding oligomerization domain containing 2 signaling pathway GO:0070432 3 0.017
lipid homeostasis GO:0055088 63 0.017
digestive system development GO:0055123 200 0.017
digestive tract development GO:0048565 190 0.017
rhythmic process GO:0048511 174 0.017
positive regulation by symbiont of host immune response GO:0052556 1 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.017
positive regulation of neuron differentiation GO:0045666 141 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
kidney development GO:0001822 213 0.017
positive regulation of vasoconstriction GO:0045907 4 0.017
cytokine metabolic process GO:0042107 71 0.017
Zebrafish Mouse
regulation of peptidase activity GO:0052547 96 0.017
negative regulation of cytokine production GO:0001818 84 0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.017
muscle contraction GO:0006936 101 0.017
regulation of transferase activity GO:0051338 263 0.017
neural tube formation GO:0001841 108 0.017
positive regulation of cell death GO:0010942 224 0.017
positive regulation of peptidase activity GO:0010952 49 0.017
heterocycle catabolic process GO:0046700 280 0.017
t cell homeostasis GO:0043029 35 0.017
lipid biosynthetic process GO:0008610 179 0.017
negative regulation of cell cycle GO:0045786 123 0.017
response to light stimulus GO:0009416 135 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
negative regulation of multi organism process GO:0043901 68 0.017
positive regulation of homeostatic process GO:0032846 64 0.017
negative regulation of protein processing GO:0010955 79 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
fertilization GO:0009566 127 0.016
regulation of binding GO:0051098 111 0.016
Mouse
extracellular structure organization GO:0043062 148 0.016
modulation by symbiont of host immune response GO:0052553 1 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
regionalization GO:0003002 337 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
respiratory tube development GO:0030323 167 0.016
cell activation involved in immune response GO:0002263 126 0.016
Mouse
positive regulation of cell motility GO:2000147 116 0.016
positive regulation of intracellular transport GO:0032388 70 0.016
activation of cysteine type endopeptidase activity GO:0097202 27 0.016
tumor necrosis factor production GO:0032640 50 0.016
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.016
detection of external biotic stimulus GO:0098581 9 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
positive regulation of transferase activity GO:0051347 167 0.016
blood coagulation GO:0007596 76 0.016
icosanoid metabolic process GO:0006690 33 0.016
dendrite development GO:0016358 115 0.016
adult behavior GO:0030534 135 0.016
negative regulation of growth of symbiont in host GO:0044130 19 0.016
stem cell differentiation GO:0048863 268 0.016
multicellular organismal signaling GO:0035637 91 0.016
spermatid differentiation GO:0048515 115 0.016
regulation of production of molecular mediator of immune response GO:0002700 65 0.016
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathway GO:0070430 1 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
calcium ion homeostasis GO:0055074 127 0.016
immunoglobulin production GO:0002377 73 0.016
response to host GO:0075136 3 0.016
phenol containing compound metabolic process GO:0018958 60 0.016
positive regulation of cytokine secretion GO:0050715 41 0.016
heart morphogenesis GO:0003007 178 0.016
regulation of neuron differentiation GO:0045664 281 0.016
regulation of intracellular transport GO:0032386 159 0.015
nitric oxide production involved in inflammatory response GO:0002537 2 0.015
ras protein signal transduction GO:0007265 77 0.015
monocarboxylic acid biosynthetic process GO:0072330 61 0.015
b cell differentiation GO:0030183 78 0.015
positive regulation of chemokine production GO:0032722 22 0.015
leukocyte homeostasis GO:0001776 79 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
mitotic cell cycle process GO:1903047 159 0.015
protein ubiquitination GO:0016567 171 0.015
Mouse
positive regulation of nucleotide binding oligomerization domain containing signaling pathway GO:0070426 2 0.015
nucleoside metabolic process GO:0009116 246 0.015
cellular response to abiotic stimulus GO:0071214 56 0.015
cellular response to amino acid stimulus GO:0071230 29 0.015
positive regulation of growth GO:0045927 104 0.015
protein oligomerization GO:0051259 67 0.015
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.015
small molecule biosynthetic process GO:0044283 132 0.015
regulation of ion transport GO:0043269 215 0.015
organic acid biosynthetic process GO:0016053 86 0.015
negative regulation of leukocyte proliferation GO:0070664 46 0.015
muscle cell differentiation GO:0042692 261 0.015
morphogenesis of embryonic epithelium GO:0016331 159 0.015
lung development GO:0030324 164 0.015
regulation of neuron death GO:1901214 134 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
synaptic transmission GO:0007268 329 0.015
hormone secretion GO:0046879 128 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
positive regulation of interferon gamma production GO:0032729 39 0.015
protein targeting GO:0006605 143 0.015
connective tissue development GO:0061448 179 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
regulation of protein kinase activity GO:0045859 232 0.014
learning or memory GO:0007611 148 0.014
endomembrane system organization GO:0010256 147 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
regulation of endopeptidase activity GO:0052548 89 0.014
leukocyte mediated cytotoxicity GO:0001909 62 0.014
stem cell development GO:0048864 219 0.014
placenta development GO:0001890 140 0.014
immunoglobulin mediated immune response GO:0016064 69 0.014
response to radiation GO:0009314 165 0.014
positive regulation of cell development GO:0010720 237 0.014
regulation of interleukin 23 production GO:0032667 2 0.014
response to amino acid GO:0043200 37 0.014
cognition GO:0050890 149 0.014
pallium development GO:0021543 120 0.014
fatty acid derivative metabolic process GO:1901568 33 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
peptidyl serine modification GO:0018209 83 0.014
appendage morphogenesis GO:0035107 149 0.014
ear development GO:0043583 200 0.014
cell substrate adhesion GO:0031589 130 0.014
modulation by organism of defense related nitric oxide production in other organism involved in symbiotic interaction GO:0052302 1 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
regulation of protein processing GO:0070613 96 0.014
gliogenesis GO:0042063 141 0.014
compound eye development GO:0048749 1 0.014
regulation of erk1 and erk2 cascade GO:0070372 71 0.014
tissue remodeling GO:0048771 102 0.014
oxidation reduction process GO:0055114 342 0.014
regulation of nitric oxide biosynthetic process GO:0045428 18 0.014
Mouse
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.014
respiratory system development GO:0060541 190 0.014
regulation of peptide transport GO:0090087 91 0.014
regulation of lymphocyte mediated immunity GO:0002706 84 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
regulation of blood vessel size GO:0050880 56 0.013
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
growth involved in symbiotic interaction GO:0044110 23 0.013
telencephalon development GO:0021537 186 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
translation GO:0006412 93 0.013
carbohydrate homeostasis GO:0033500 128 0.013
cytokine biosynthetic process GO:0042089 68 0.013
Zebrafish Mouse
cellularization GO:0007349 1 0.013
organelle fission GO:0048285 170 0.013
t cell proliferation GO:0042098 120 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
regulation of kinase activity GO:0043549 249 0.013
hindbrain development GO:0030902 128 0.013
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.013
epithelial cell development GO:0002064 159 0.013
positive regulation by organism of defense related nitric oxide production in other organism involved in symbiotic interaction GO:0052345 1 0.013
multicellular organism growth GO:0035264 161 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
monocarboxylic acid transport GO:0015718 44 0.013
meiotic nuclear division GO:0007126 115 0.013
metencephalon development GO:0022037 89 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
regulation of leukocyte mediated immunity GO:0002703 104 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
intracellular protein transport GO:0006886 204 0.013
positive regulation of endopeptidase activity GO:0010950 43 0.013
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.013
t cell differentiation in thymus GO:0033077 77 0.013

Ticam2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.050
nervous system disease DOID:863 0 0.050
disease of cellular proliferation DOID:14566 0 0.048
cancer DOID:162 0 0.044
retinal disease DOID:5679 0 0.029
sensory system disease DOID:0050155 0 0.029
eye and adnexa disease DOID:1492 0 0.029
eye disease DOID:5614 0 0.029
organ system cancer DOID:0050686 0 0.019
disease of metabolism DOID:0014667 0 0.018