Mus musculus

0 known processes

Timm8a1

translocase of inner mitochondrial membrane 8 homolog a1 (yeast)

(Aliases: Tim8a,Timm8a,Fci-12,Ddp1,DXHXS1274E)

Timm8a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitochondrion organization GO:0007005 134 0.840
mitochondrial transport GO:0006839 36 0.728
transmembrane transport GO:0055085 412 0.395
mitochondrial translation GO:0032543 4 0.290
protein localization to mitochondrion GO:0070585 15 0.277
regulation of mitochondrion organization GO:0010821 27 0.187
protein targeting to mitochondrion GO:0006626 6 0.135
positive regulation of mitochondrion organization GO:0010822 17 0.131
protein processing GO:0016485 163 0.120
cytoplasmic transport GO:0016482 234 0.117
cellular nitrogen compound catabolic process GO:0044270 280 0.116
mitochondrial membrane organization GO:0007006 26 0.089
nucleotide metabolic process GO:0009117 332 0.086
cellular lipid metabolic process GO:0044255 323 0.078
activation of cysteine type endopeptidase activity GO:0097202 27 0.077
inner mitochondrial membrane organization GO:0007007 5 0.075
cellular metal ion homeostasis GO:0006875 151 0.072
protein localization to organelle GO:0033365 185 0.067
rna catabolic process GO:0006401 29 0.063
purine ribonucleotide biosynthetic process GO:0009152 59 0.057
aromatic compound catabolic process GO:0019439 286 0.056
regulation of hydrolase activity GO:0051336 246 0.053
development of primary sexual characteristics GO:0045137 143 0.052
regulation of feeding behavior GO:0060259 3 0.050
generation of precursor metabolites and energy GO:0006091 103 0.048
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.048
positive regulation of hydrolase activity GO:0051345 148 0.048
organic acid biosynthetic process GO:0016053 86 0.047
carbohydrate homeostasis GO:0033500 128 0.046
organic cyclic compound catabolic process GO:1901361 295 0.046
nucleobase containing small molecule metabolic process GO:0055086 352 0.045
oxidation reduction process GO:0055114 342 0.045
establishment of protein localization to organelle GO:0072594 118 0.044
regulation of organelle organization GO:0033043 289 0.044
protein maturation GO:0051604 176 0.044
cellular homeostasis GO:0019725 240 0.043
gland development GO:0048732 330 0.042
establishment of protein localization to mitochondrion GO:0072655 11 0.042
protein targeting GO:0006605 143 0.042
lipid biosynthetic process GO:0008610 179 0.041
amine metabolic process GO:0009308 45 0.040
organonitrogen compound biosynthetic process GO:1901566 192 0.040
myeloid cell differentiation GO:0030099 233 0.038
regulation of membrane potential GO:0042391 192 0.037
organophosphate biosynthetic process GO:0090407 122 0.037
gonad development GO:0008406 141 0.036
positive regulation of peptidase activity GO:0010952 49 0.035
response to oxidative stress GO:0006979 123 0.035
spermatogenesis GO:0007283 284 0.035
heterocycle catabolic process GO:0046700 280 0.033
defecation GO:0030421 1 0.033
establishment of protein localization to mitochondrial membrane GO:0090151 2 0.033
metal ion homeostasis GO:0055065 189 0.032
male gamete generation GO:0048232 285 0.032
ion transmembrane transport GO:0034220 361 0.031
regulation of apoptotic signaling pathway GO:2001233 197 0.030
regulation of cysteine type endopeptidase activity GO:2000116 65 0.030
regulation of phospholipid biosynthetic process GO:0071071 3 0.029
carbohydrate derivative biosynthetic process GO:1901137 183 0.029
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.028
sphingolipid metabolic process GO:0006665 45 0.028
mitochondrion morphogenesis GO:0070584 13 0.027
glucose homeostasis GO:0042593 128 0.026
positive regulation of cell death GO:0010942 224 0.026
positive regulation of apoptotic process GO:0043065 217 0.026
cofactor transport GO:0051181 4 0.026
nucleotide biosynthetic process GO:0009165 78 0.026
intracellular protein transport GO:0006886 204 0.026
positive regulation of endopeptidase activity GO:0010950 43 0.026
immune response regulating signaling pathway GO:0002764 125 0.026
regulation of endopeptidase activity GO:0052548 89 0.025
endocytosis GO:0006897 168 0.025
protein import GO:0017038 101 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
mrna metabolic process GO:0016071 84 0.024
cellular amino acid metabolic process GO:0006520 103 0.023
multicellular organism growth GO:0035264 161 0.023
divalent inorganic cation homeostasis GO:0072507 138 0.023
dna catabolic process GO:0006308 19 0.023
cellular amine metabolic process GO:0044106 44 0.023
purine nucleotide biosynthetic process GO:0006164 65 0.022
protein transmembrane transport GO:0071806 8 0.022
cellular response to oxidative stress GO:0034599 76 0.021
phospholipid metabolic process GO:0006644 87 0.021
cell type specific apoptotic process GO:0097285 268 0.021
neuron apoptotic process GO:0051402 142 0.020
positive regulation of cell development GO:0010720 237 0.020
locomotory behavior GO:0007626 195 0.020
negative regulation of cellular amine metabolic process GO:0033239 1 0.020
response to organonitrogen compound GO:0010243 246 0.020
regulation of peptidase activity GO:0052547 96 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.019
anion transport GO:0006820 177 0.019
small molecule biosynthetic process GO:0044283 132 0.019
nitrogen compound transport GO:0071705 271 0.019
apoptotic signaling pathway GO:0097190 306 0.018
nucleoside phosphate biosynthetic process GO:1901293 79 0.018
production of molecular mediator of immune response GO:0002440 103 0.018
cellular chemical homeostasis GO:0055082 215 0.018
cation transport GO:0006812 399 0.018
cellular ion homeostasis GO:0006873 165 0.018
positive regulation of immune response to tumor cell GO:0002839 6 0.018
ribonucleotide biosynthetic process GO:0009260 59 0.018
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.018
response to growth factor GO:0070848 198 0.017
cation homeostasis GO:0055080 212 0.017
response to inorganic substance GO:0010035 96 0.017
negative regulation of immune system process GO:0002683 209 0.017
glycerolipid metabolic process GO:0046486 122 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
cellular response to carbohydrate stimulus GO:0071322 50 0.016
cellularization GO:0007349 1 0.016
homeostasis of number of cells GO:0048872 210 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
lung development GO:0030324 164 0.016
sensory perception GO:0007600 245 0.016
germ cell development GO:0007281 185 0.016
calcium ion homeostasis GO:0055074 127 0.016
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
regulation of interferon gamma production GO:0032649 57 0.015
regulation of mitochondrial fission GO:0090140 3 0.015
regulation of mitochondrial membrane potential GO:0051881 17 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
regulation of macrophage activation GO:0043030 17 0.015
regulation of response to biotic stimulus GO:0002831 38 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
regulation of lipid metabolic process GO:0019216 118 0.014
negative regulation of phospholipid biosynthetic process GO:0071072 1 0.014
regulation of body fluid levels GO:0050878 162 0.014
regulation of hormone levels GO:0010817 211 0.014
ribosome biogenesis GO:0042254 20 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
positive regulation of proteolysis GO:0045862 85 0.014
protein oligomerization GO:0051259 67 0.014
membrane organization GO:0061024 245 0.014
cellular respiration GO:0045333 38 0.014
glycerophospholipid metabolic process GO:0006650 71 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
urogenital system development GO:0001655 261 0.014
cation transmembrane transport GO:0098655 266 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
lymphocyte proliferation GO:0046651 164 0.014
zymogen activation GO:0031638 41 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
regulation of interleukin 6 production GO:0032675 55 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
innate immune response GO:0045087 157 0.013
sequestering of calcium ion GO:0051208 18 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
apoptotic mitochondrial changes GO:0008637 48 0.013
response to nutrient levels GO:0031667 109 0.013
epithelial cell proliferation GO:0050673 174 0.013
forebrain development GO:0030900 302 0.013
regulation of cell activation GO:0050865 289 0.012
alpha amino acid metabolic process GO:1901605 59 0.012
divalent inorganic cation transport GO:0072511 178 0.012
blood circulation GO:0008015 195 0.012
ribose phosphate metabolic process GO:0019693 291 0.012
protein methylation GO:0006479 81 0.012
activation of immune response GO:0002253 138 0.012
respiratory tube development GO:0030323 167 0.012
positive regulation of mitochondrial fission GO:0090141 2 0.012
transition metal ion homeostasis GO:0055076 54 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
regulation of cellular amine metabolic process GO:0033238 20 0.012
regulation of t cell activation GO:0050863 170 0.012
nucleoside phosphate metabolic process GO:0006753 338 0.012
positive regulation of immune effector process GO:0002699 107 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
positive regulation of growth GO:0045927 104 0.011
ribose phosphate biosynthetic process GO:0046390 59 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
divalent metal ion transport GO:0070838 172 0.011
adenine nucleotide transport GO:0051503 2 0.011
pharynx development GO:0060465 1 0.011
cell aging GO:0007569 35 0.011
cytokine production GO:0001816 319 0.011
immunoglobulin production GO:0002377 73 0.011
cytokine production involved in immune response GO:0002367 34 0.011
regulation of myeloid cell differentiation GO:0045637 96 0.011
immune response activating signal transduction GO:0002757 116 0.011
protein tetramerization GO:0051262 23 0.011
regulation of hormone secretion GO:0046883 88 0.010
regulation of generation of precursor metabolites and energy GO:0043467 38 0.010
glycosyl compound metabolic process GO:1901657 246 0.010
negative regulation of cellular protein metabolic process GO:0032269 247 0.010
negative regulation of alcohol biosynthetic process GO:1902931 4 0.010
t cell activation GO:0042110 289 0.010
defense response to bacterium GO:0042742 119 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
regulation of neuron differentiation GO:0045664 281 0.010
response to oxygen levels GO:0070482 62 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010

Timm8a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.030
inherited metabolic disorder DOID:655 0 0.030
hemorrhagic disease DOID:2213 0 0.024
immune system disease DOID:2914 0 0.024
disease of anatomical entity DOID:7 0 0.024
blood coagulation disease DOID:1247 0 0.024
hematopoietic system disease DOID:74 0 0.024
central nervous system disease DOID:331 0 0.011
nervous system disease DOID:863 0 0.011