Mus musculus

273 known processes

Tirap

toll-interleukin 1 receptor (TIR) domain-containing adaptor protein

(Aliases: Wyatt,Tlr4ap,C130027E04Rik,AA407980,Mal)

Tirap biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytokine production GO:0001816 319 0.232
regulation of cytokine production GO:0001817 266 0.224
immune response regulating signaling pathway GO:0002764 125 0.185
positive regulation of innate immune response GO:0045089 80 0.183
activation of innate immune response GO:0002218 56 0.161
regulation of interleukin 6 production GO:0032675 55 0.135
cellular amino acid metabolic process GO:0006520 103 0.132
regulation of secretion GO:0051046 274 0.127
regulation of defense response GO:0031347 233 0.123
pattern recognition receptor signaling pathway GO:0002221 47 0.122
response to molecule of bacterial origin GO:0002237 143 0.117
activation of immune response GO:0002253 138 0.114
regulation of innate immune response GO:0045088 91 0.110
cellular response to molecule of bacterial origin GO:0071219 83 0.104
regulation of cellular ketone metabolic process GO:0010565 66 0.102
negative regulation of cytokine production GO:0001818 84 0.097
positive regulation of mapk cascade GO:0043410 170 0.095
Human
cellular ketone metabolic process GO:0042180 84 0.094
cellular response to lipopolysaccharide GO:0071222 77 0.094
inflammatory response GO:0006954 244 0.093
negative regulation of protein metabolic process GO:0051248 282 0.092
apoptotic signaling pathway GO:0097190 306 0.090
negative regulation of intracellular signal transduction GO:1902532 167 0.089
b cell activation GO:0042113 161 0.085
regulation of response to wounding GO:1903034 189 0.085
innate immune response GO:0045087 157 0.083
response to lipopolysaccharide GO:0032496 128 0.083
Human
negative regulation of immune system process GO:0002683 209 0.082
cellular response to lipid GO:0071396 145 0.080
positive regulation of defense response GO:0031349 124 0.079
regulation of cellular amino acid metabolic process GO:0006521 5 0.079
posttranscriptional regulation of gene expression GO:0010608 155 0.077
Human
regulation of secretion by cell GO:1903530 249 0.077
interleukin 6 secretion GO:0072604 3 0.074
regulation of cellular amine metabolic process GO:0033238 20 0.072
regulation of cell activation GO:0050865 289 0.071
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.067
translation GO:0006412 93 0.066
regulation of mapk cascade GO:0043408 248 0.065
Human
positive regulation of cellular amine metabolic process GO:0033240 5 0.061
cellular response to biotic stimulus GO:0071216 92 0.058
regulation of transferase activity GO:0051338 263 0.055
leukocyte differentiation GO:0002521 342 0.055
regulation of inflammatory response GO:0050727 147 0.054
carbohydrate metabolic process GO:0005975 230 0.054
defense response to bacterium GO:0042742 119 0.053
detection of molecule of bacterial origin GO:0032490 2 0.052
mapk cascade GO:0000165 281 0.052
Human
negative regulation of lymphocyte activation GO:0051250 91 0.051
cellular response to cytokine stimulus GO:0071345 189 0.051
negative regulation of cellular protein metabolic process GO:0032269 247 0.051
cell adhesion GO:0007155 329 0.050
regulation of cytokine secretion GO:0050707 61 0.050
leukocyte proliferation GO:0070661 172 0.050
cytoplasmic transport GO:0016482 234 0.050
toll like receptor 4 signaling pathway GO:0034142 9 0.050
Human
cytokine mediated signaling pathway GO:0019221 115 0.049
regulation of establishment of protein localization GO:0070201 181 0.048
regulation of protein transport GO:0051223 163 0.047
nitrogen compound transport GO:0071705 271 0.047
peptidyl amino acid modification GO:0018193 336 0.047
negative regulation of cell activation GO:0050866 111 0.047
negative regulation of phosphorus metabolic process GO:0010563 184 0.046
interleukin 6 production GO:0032635 58 0.045
regulation of translation GO:0006417 71 0.045
regulation of protein localization GO:0032880 231 0.045
amine metabolic process GO:0009308 45 0.045
cellular amine metabolic process GO:0044106 44 0.045
cation transport GO:0006812 399 0.044
protein secretion GO:0009306 111 0.043
leukocyte mediated immunity GO:0002443 174 0.042
multicellular organismal homeostasis GO:0048871 164 0.042
regulation of protein secretion GO:0050708 82 0.041
negative regulation of phosphate metabolic process GO:0045936 184 0.041
cellular lipid metabolic process GO:0044255 323 0.041
regulation of protein kinase activity GO:0045859 232 0.041
t cell activation GO:0042110 289 0.040
toll like receptor signaling pathway GO:0002224 38 0.040
innate immune response activating signal transduction GO:0002758 50 0.039
transmembrane transport GO:0055085 412 0.039
digestive system development GO:0055123 200 0.039
homeostasis of number of cells GO:0048872 210 0.039
oxidation reduction process GO:0055114 342 0.038
immune response activating signal transduction GO:0002757 116 0.038
skin development GO:0043588 220 0.038
cation transmembrane transport GO:0098655 266 0.038
regulation of kinase activity GO:0043549 249 0.037
regulation of cellular response to stress GO:0080135 159 0.036
Human
regulation of body fluid levels GO:0050878 162 0.036
positive regulation of apoptotic process GO:0043065 217 0.035
response to acid chemical GO:0001101 111 0.035
protein maturation GO:0051604 176 0.034
regulation of b cell activation GO:0050864 81 0.034
positive regulation of cell activation GO:0050867 158 0.033
intrinsic apoptotic signaling pathway GO:0097193 132 0.032
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.032
membrane organization GO:0061024 245 0.032
adaptive immune response GO:0002250 155 0.032
positive regulation of cytokine production GO:0001819 174 0.031
regulation of cellular catabolic process GO:0031329 242 0.031
muscle tissue development GO:0060537 308 0.031
immune effector process GO:0002252 321 0.031
protein catabolic process GO:0030163 221 0.031
macromolecule catabolic process GO:0009057 281 0.030
hemostasis GO:0007599 78 0.030
sensory perception GO:0007600 245 0.030
nucleobase containing small molecule metabolic process GO:0055086 352 0.030
response to organic cyclic compound GO:0014070 198 0.030
reactive oxygen species metabolic process GO:0072593 84 0.030
regulation of multi organism process GO:0043900 111 0.030
toll like receptor 7 signaling pathway GO:0034154 4 0.030
toll like receptor 2 signaling pathway GO:0034134 6 0.030
Human
negative regulation of b cell activation GO:0050869 27 0.030
negative regulation of cell proliferation GO:0008285 296 0.030
response to oxidative stress GO:0006979 123 0.029
cellular response to hormone stimulus GO:0032870 150 0.029
negative regulation of cellular amine metabolic process GO:0033239 1 0.029
tumor necrosis factor production GO:0032640 50 0.029
ion transmembrane transport GO:0034220 361 0.029
cellular response to organonitrogen compound GO:0071417 145 0.029
nucleoside metabolic process GO:0009116 246 0.029
muscle cell differentiation GO:0042692 261 0.029
peptidyl tyrosine phosphorylation GO:0018108 143 0.029
cytokine secretion GO:0050663 72 0.028
response to organonitrogen compound GO:0010243 246 0.028
glycosyl compound catabolic process GO:1901658 206 0.028
regulation of lymphocyte activation GO:0051249 240 0.028
negative regulation of interleukin 6 production GO:0032715 17 0.028
glycoprotein metabolic process GO:0009100 116 0.028
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.028
i kappab kinase nf kappab signaling GO:0007249 85 0.028
digestive tract development GO:0048565 190 0.027
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
regulation of hydrolase activity GO:0051336 246 0.027
respiratory system development GO:0060541 190 0.027
regulation of apoptotic signaling pathway GO:2001233 197 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.027
striated muscle tissue development GO:0014706 293 0.027
regulation of proteolysis GO:0030162 164 0.026
regulation of membrane potential GO:0042391 192 0.026
lymphocyte differentiation GO:0030098 242 0.026
regulation of organelle organization GO:0033043 289 0.026
detection of stimulus GO:0051606 84 0.026
cellular response to peptidoglycan GO:0071224 4 0.026
nucleotide metabolic process GO:0009117 332 0.026
negative regulation of phosphorylation GO:0042326 166 0.026
negative regulation of molecular function GO:0044092 258 0.026
positive regulation of protein kinase activity GO:0045860 144 0.026
lipid biosynthetic process GO:0008610 179 0.026
t cell proliferation GO:0042098 120 0.026
protein processing GO:0016485 163 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.025
positive regulation of nervous system development GO:0051962 221 0.025
lung development GO:0030324 164 0.025
wnt signaling pathway GO:0016055 188 0.025
cytokine biosynthetic process GO:0042089 68 0.025
regulation of cell motility GO:2000145 236 0.025
positive regulation of protein phosphorylation GO:0001934 242 0.025
organophosphate catabolic process GO:0046434 232 0.025
epithelial cell development GO:0002064 159 0.025
cellular protein catabolic process GO:0044257 155 0.025
male gamete generation GO:0048232 285 0.025
cellular chemical homeostasis GO:0055082 215 0.024
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.024
defense response to gram positive bacterium GO:0050830 50 0.024
leukocyte migration GO:0050900 124 0.024
positive regulation of cell motility GO:2000147 116 0.024
regulation of vesicle mediated transport GO:0060627 139 0.024
aromatic compound catabolic process GO:0019439 286 0.024
circulatory system process GO:0003013 197 0.024
negative regulation of protein modification process GO:0031400 163 0.024
respiratory tube development GO:0030323 167 0.024
gland development GO:0048732 330 0.024
positive regulation of cellular catabolic process GO:0031331 148 0.024
negative regulation of growth GO:0045926 99 0.023
positive regulation of secretion GO:0051047 130 0.023
ribonucleoside catabolic process GO:0042454 206 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.023
positive regulation of protein transport GO:0051222 93 0.023
regulation of interferon beta biosynthetic process GO:0045357 4 0.023
regulation of interleukin 8 production GO:0032677 3 0.023
intracellular protein transport GO:0006886 204 0.023
protein localization to organelle GO:0033365 185 0.023
cell type specific apoptotic process GO:0097285 268 0.023
blood circulation GO:0008015 195 0.023
regionalization GO:0003002 337 0.022
epithelial cell proliferation GO:0050673 174 0.022
positive regulation of protein modification process GO:0031401 299 0.022
regulation of lymphocyte proliferation GO:0050670 117 0.022
inorganic cation transmembrane transport GO:0098662 207 0.022
protein ubiquitination GO:0016567 171 0.022
regulation of hormone levels GO:0010817 211 0.022
morphogenesis of a branching epithelium GO:0061138 193 0.022
compound eye development GO:0048749 1 0.021
reactive nitrogen species metabolic process GO:2001057 0 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.021
myeloid cell homeostasis GO:0002262 114 0.021
coagulation GO:0050817 78 0.021
muscle system process GO:0003012 141 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
macromolecule glycosylation GO:0043413 55 0.021
hexose metabolic process GO:0019318 98 0.021
modification dependent protein catabolic process GO:0019941 133 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.021
positive regulation of kinase activity GO:0033674 155 0.021
purine containing compound metabolic process GO:0072521 311 0.021
negative regulation of translation GO:0017148 22 0.021
regulation of wnt signaling pathway GO:0030111 123 0.021
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.020
lymphocyte mediated immunity GO:0002449 139 0.020
positive regulation of interferon alpha production GO:0032727 4 0.020
epithelial tube morphogenesis GO:0060562 303 0.020
divalent inorganic cation transport GO:0072511 178 0.020
response to radiation GO:0009314 165 0.020
stem cell differentiation GO:0048863 268 0.020
negative regulation of leukocyte proliferation GO:0070664 46 0.020
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.020
cellular response to acid chemical GO:0071229 68 0.020
glycoprotein biosynthetic process GO:0009101 89 0.020
lipid transport GO:0006869 98 0.020
glycerolipid biosynthetic process GO:0045017 50 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
single organism cell adhesion GO:0098602 156 0.020
wound healing GO:0042060 157 0.020
negative regulation of multi organism process GO:0043901 68 0.020
localization within membrane GO:0051668 4 0.020
morphogenesis of embryonic epithelium GO:0016331 159 0.020
cell maturation GO:0048469 127 0.019
anion transport GO:0006820 177 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
t cell differentiation GO:0030217 174 0.019
blood coagulation GO:0007596 76 0.019
cell substrate adhesion GO:0031589 130 0.019
endomembrane system organization GO:0010256 147 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
response to light stimulus GO:0009416 135 0.019
phosphatidylinositol mediated signaling GO:0048015 41 0.019
regulation of cytokine biosynthetic process GO:0042035 59 0.019
lymphocyte proliferation GO:0046651 164 0.019
mitotic cell cycle GO:0000278 195 0.019
skeletal muscle organ development GO:0060538 163 0.019
interspecies interaction between organisms GO:0044419 83 0.019
spermatogenesis GO:0007283 284 0.019
ossification GO:0001503 216 0.018
negative regulation of protein phosphorylation GO:0001933 126 0.018
cation homeostasis GO:0055080 212 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
protein targeting GO:0006605 143 0.018
organophosphate biosynthetic process GO:0090407 122 0.018
fat cell differentiation GO:0045444 160 0.018
learning or memory GO:0007611 148 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
translational initiation GO:0006413 24 0.018
positive regulation of cell death GO:0010942 224 0.018
response to molecule of fungal origin GO:0002238 4 0.018
response to inorganic substance GO:0010035 96 0.018
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.018
cellular response to oxidative stress GO:0034599 76 0.018
nucleoside catabolic process GO:0009164 206 0.018
positive regulation of map kinase activity GO:0043406 84 0.018
defense response to other organism GO:0098542 197 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
lymphocyte activation involved in immune response GO:0002285 93 0.018
engulfment of apoptotic cell GO:0043652 3 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
exocytosis GO:0006887 121 0.017
urogenital system development GO:0001655 261 0.017
endocytosis GO:0006897 168 0.017
small molecule biosynthetic process GO:0044283 132 0.017
regulation of organ morphogenesis GO:2000027 144 0.017
muscle contraction GO:0006936 101 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.017
negative regulation of cell development GO:0010721 169 0.017
negative regulation of nervous system development GO:0051961 156 0.017
cellular response to dna damage stimulus GO:0006974 207 0.017
cell activation involved in immune response GO:0002263 126 0.017
epidermis development GO:0008544 187 0.017
regulation of system process GO:0044057 200 0.017
regulation of anatomical structure size GO:0090066 178 0.017
heart morphogenesis GO:0003007 178 0.017
regulation of neuron differentiation GO:0045664 281 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
regulation of chemokine production GO:0032642 30 0.017
lipid localization GO:0010876 126 0.017
monosaccharide metabolic process GO:0005996 106 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
dna metabolic process GO:0006259 303 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.017
germ cell development GO:0007281 185 0.017
sequestering of metal ion GO:0051238 19 0.017
negative regulation of translational initiation GO:0045947 4 0.016
protein kinase b signaling GO:0043491 74 0.016
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
neural precursor cell proliferation GO:0061351 121 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
amide transport GO:0042886 138 0.016
regulation of protein processing GO:0070613 96 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
myotube differentiation GO:0014902 105 0.016
regulation of cell projection organization GO:0031344 206 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
organic acid transport GO:0015849 101 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
glycerophospholipid metabolic process GO:0006650 71 0.016
leukocyte homeostasis GO:0001776 79 0.016
morphogenesis of a branching structure GO:0001763 203 0.016
lateral inhibition GO:0046331 1 0.016
actin cytoskeleton organization GO:0030036 220 0.016
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
neuron death GO:0070997 154 0.016
regulation of homeostatic process GO:0032844 182 0.016
maintenance of location GO:0051235 89 0.016
regulation of ion transport GO:0043269 215 0.016
mitochondrion organization GO:0007005 134 0.016
negative regulation of protein maturation GO:1903318 79 0.016
positive regulation of interleukin 18 production GO:0032741 2 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
inositol lipid mediated signaling GO:0048017 41 0.016
regulation of myotube differentiation GO:0010830 62 0.016
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.016
proteasomal protein catabolic process GO:0010498 98 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.016
protein import GO:0017038 101 0.016
small gtpase mediated signal transduction GO:0007264 97 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
purine containing compound catabolic process GO:0072523 213 0.015
b cell proliferation GO:0042100 53 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
regulation of protein maturation GO:1903317 96 0.015
carboxylic acid transport GO:0046942 100 0.015
cellular response to abiotic stimulus GO:0071214 56 0.015
response to bacterial lipoprotein GO:0032493 4 0.015
regulation of b cell proliferation GO:0030888 39 0.015
negative regulation of secretion by cell GO:1903531 54 0.015
regulation of protein kinase b signaling GO:0051896 56 0.015
protein localization to nucleus GO:0034504 121 0.015
lymphocyte apoptotic process GO:0070227 54 0.015
heterocycle catabolic process GO:0046700 280 0.015
transmission of nerve impulse GO:0019226 76 0.015
developmental maturation GO:0021700 193 0.015
peptide transport GO:0015833 133 0.015
sensory organ morphogenesis GO:0090596 242 0.015
protein glycosylation GO:0006486 55 0.015
antimicrobial peptide production GO:0002775 2 0.015
regulation of cell adhesion GO:0030155 154 0.015
chromatin modification GO:0016568 187 0.015
b cell differentiation GO:0030183 78 0.015
connective tissue development GO:0061448 179 0.015
tissue homeostasis GO:0001894 115 0.015
regulation of toll like receptor signaling pathway GO:0034121 20 0.015
negative regulation of kinase activity GO:0033673 81 0.015
extracellular matrix organization GO:0030198 147 0.015
interleukin 8 production GO:0032637 4 0.015
leukocyte apoptotic process GO:0071887 71 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
nuclear import GO:0051170 95 0.015
protein localization to membrane GO:0072657 108 0.014
positive regulation of immune effector process GO:0002699 107 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
positive regulation of neuron differentiation GO:0045666 141 0.014
positive regulation of cell migration GO:0030335 109 0.014
response to growth factor GO:0070848 198 0.014
forebrain development GO:0030900 302 0.014
organic hydroxy compound transport GO:0015850 93 0.014
organic anion transport GO:0015711 137 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
response to insulin GO:0032868 100 0.014
steroid metabolic process GO:0008202 119 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
metal ion homeostasis GO:0055065 189 0.014
action potential GO:0001508 78 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
response to extracellular stimulus GO:0009991 127 0.014
organelle localization GO:0051640 179 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
regulation of cellular component size GO:0032535 121 0.014
regulation of translational initiation GO:0006446 15 0.014
response to steroid hormone GO:0048545 56 0.014
canonical wnt signaling pathway GO:0060070 130 0.014
positive regulation of jnk cascade GO:0046330 46 0.014
Human
establishment of organelle localization GO:0051656 122 0.014
cytokine metabolic process GO:0042107 71 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.014
interferon gamma production GO:0032609 67 0.014
sequestering of calcium ion GO:0051208 18 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
response to peptide GO:1901652 136 0.014
negative regulation of t cell activation GO:0050868 65 0.014
stress activated protein kinase signaling cascade GO:0031098 81 0.014
Human
purine ribonucleoside catabolic process GO:0046130 205 0.014
single organism nuclear import GO:1902593 95 0.014
locomotory behavior GO:0007626 195 0.014
carbohydrate homeostasis GO:0033500 128 0.013
negative regulation of secretion GO:0051048 61 0.013
gonad development GO:0008406 141 0.013
gastrulation GO:0007369 116 0.013
regulation of striated muscle cell differentiation GO:0051153 81 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
cellular response to external stimulus GO:0071496 88 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
glycerophospholipid biosynthetic process GO:0046474 32 0.013
renal system development GO:0072001 225 0.013
kidney development GO:0001822 213 0.013
striated muscle cell development GO:0055002 125 0.013
alcohol metabolic process GO:0006066 116 0.013
response to peptide hormone GO:0043434 127 0.013
digestive tract morphogenesis GO:0048546 147 0.013
regulation of binding GO:0051098 111 0.013
Human
glycosylation GO:0070085 62 0.013
negative regulation of protein transport GO:0051224 46 0.013
tissue remodeling GO:0048771 102 0.013
ameboidal type cell migration GO:0001667 128 0.013
positive regulation of stress activated mapk cascade GO:0032874 48 0.013
Human
regulation of cell cycle GO:0051726 281 0.013
alpha beta t cell activation GO:0046631 91 0.013
neuronal action potential GO:0019228 54 0.013
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.013
regulation of blood pressure GO:0008217 93 0.013
plasma membrane organization GO:0007009 90 0.013
skeletal system morphogenesis GO:0048705 203 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.013
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.013
positive regulation of transferase activity GO:0051347 167 0.013
cognition GO:0050890 149 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
blood vessel morphogenesis GO:0048514 285 0.013
positive regulation of interleukin 8 production GO:0032757 2 0.013
regulation of leukocyte proliferation GO:0070663 121 0.013
chromatin organization GO:0006325 206 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
cellular homeostasis GO:0019725 240 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
positive regulation of antimicrobial peptide production GO:0002225 1 0.013
regulation of muscle tissue development GO:1901861 97 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
peptidyl serine modification GO:0018209 83 0.013
cellularization GO:0007349 1 0.013
skeletal system development GO:0001501 356 0.013
positive regulation of protein secretion GO:0050714 52 0.013
stem cell proliferation GO:0072089 117 0.012
response to amino acid GO:0043200 37 0.012
multicellular organismal signaling GO:0035637 91 0.012
single organismal cell cell adhesion GO:0016337 131 0.012
glucose homeostasis GO:0042593 128 0.012
divalent metal ion transport GO:0070838 172 0.012
olfactory learning GO:0008355 2 0.012
intestinal epithelial structure maintenance GO:0060729 4 0.012
positive regulation of antimicrobial humoral response GO:0002760 2 0.012
phospholipid metabolic process GO:0006644 87 0.012
positive regulation of interleukin 6 production GO:0032755 37 0.012
regulation of antimicrobial peptide production GO:0002784 1 0.012
protein import into nucleus GO:0006606 95 0.012
regulation of protein catabolic process GO:0042176 108 0.012
notch signaling pathway GO:0007219 71 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
neural tube development GO:0021915 160 0.012
regulation of ossification GO:0030278 112 0.012
organelle fission GO:0048285 170 0.012
cellular response to peptide hormone stimulus GO:0071375 92 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
positive regulation of apoptotic signaling pathway GO:2001235 95 0.012
calcium ion homeostasis GO:0055074 127 0.012
glucose metabolic process GO:0006006 92 0.012
cartilage development GO:0051216 140 0.012
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.012
Human
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.012
insulin receptor signaling pathway GO:0008286 49 0.012
carbohydrate biosynthetic process GO:0016051 74 0.012
interferon beta biosynthetic process GO:0045350 4 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.012
negative regulation of defense response GO:0031348 77 0.012

Tirap disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.038
disease of anatomical entity DOID:7 0 0.038
disease of metabolism DOID:0014667 0 0.037
eye and adnexa disease DOID:1492 0 0.036
sensory system disease DOID:0050155 0 0.036
cancer DOID:162 0 0.034
disease of cellular proliferation DOID:14566 0 0.034
organ system cancer DOID:0050686 0 0.034
eye disease DOID:5614 0 0.033
retinal disease DOID:5679 0 0.021
retinal degeneration DOID:8466 0 0.021
inherited metabolic disorder DOID:655 0 0.018
immune system disease DOID:2914 0 0.018
musculoskeletal system disease DOID:17 0 0.018
immune system cancer DOID:0060083 0 0.015
hematologic cancer DOID:2531 0 0.015
hematopoietic system disease DOID:74 0 0.015