Mus musculus

7 known processes

Tjap1

tight junction associated protein 1

(Aliases: AW121008,0610041D19Rik,Tjp4,Pilt,AI415281)

Tjap1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rac protein signal transduction GO:0016601 13 0.298
ras protein signal transduction GO:0007265 77 0.208
small gtpase mediated signal transduction GO:0007264 97 0.187
male gamete generation GO:0048232 285 0.118
actin cytoskeleton organization GO:0030036 220 0.116
establishment or maintenance of cell polarity GO:0007163 86 0.102
regulation of neuron projection development GO:0010975 169 0.089
regulation of ras protein signal transduction GO:0046578 114 0.087
macromolecule glycosylation GO:0043413 55 0.085
protein localization to endosome GO:0036010 2 0.075
regulation of cellular component biogenesis GO:0044087 181 0.075
regulation of neuron differentiation GO:0045664 281 0.074
spermatogenesis GO:0007283 284 0.071
regulation of protein localization GO:0032880 231 0.071
positive regulation of protein complex assembly GO:0031334 45 0.069
regulation of anatomical structure size GO:0090066 178 0.068
protein localization to organelle GO:0033365 185 0.065
regulation of organelle organization GO:0033043 289 0.065
carbohydrate metabolic process GO:0005975 230 0.063
regulation of actin filament based process GO:0032970 99 0.063
glycoprotein biosynthetic process GO:0009101 89 0.062
positive regulation of organelle organization GO:0010638 128 0.060
positive regulation of protein modification process GO:0031401 299 0.060
protein polymerization GO:0051258 57 0.060
membrane organization GO:0061024 245 0.057
regulation of protein kinase activity GO:0045859 232 0.056
myotube differentiation GO:0014902 105 0.056
carbohydrate derivative biosynthetic process GO:1901137 183 0.056
regulation of cell projection organization GO:0031344 206 0.055
plasma membrane organization GO:0007009 90 0.054
cell type specific apoptotic process GO:0097285 268 0.054
protein glycosylation GO:0006486 55 0.053
protein localization to membrane GO:0072657 108 0.053
regulation of cytoskeleton organization GO:0051493 122 0.053
positive regulation of cellular component biogenesis GO:0044089 94 0.052
cell division GO:0051301 120 0.052
cellular amine metabolic process GO:0044106 44 0.052
actin filament organization GO:0007015 113 0.052
actin filament polymerization GO:0030041 44 0.051
organic cyclic compound catabolic process GO:1901361 295 0.051
cellular amino acid metabolic process GO:0006520 103 0.050
positive regulation of programmed cell death GO:0043068 218 0.050
regulation of cellular component size GO:0032535 121 0.050
purine nucleoside metabolic process GO:0042278 241 0.050
regulation of apoptotic signaling pathway GO:2001233 197 0.049
actin polymerization or depolymerization GO:0008154 54 0.049
regulation of actin cytoskeleton organization GO:0032956 84 0.047
positive regulation of cytoskeleton organization GO:0051495 49 0.047
regulation of rac protein signal transduction GO:0035020 19 0.046
regulation of cellular ketone metabolic process GO:0010565 66 0.046
regulation of mapk cascade GO:0043408 248 0.046
regulation of actin filament polymerization GO:0030833 38 0.046
glycosylation GO:0070085 62 0.046
regulation of protein complex assembly GO:0043254 83 0.045
apoptotic signaling pathway GO:0097190 306 0.044
ribonucleoside triphosphate metabolic process GO:0009199 220 0.044
regulation of cellular catabolic process GO:0031329 242 0.043
glycoprotein metabolic process GO:0009100 116 0.042
positive regulation of cellular catabolic process GO:0031331 148 0.042
protein localization to plasma membrane GO:0072659 57 0.042
lipid biosynthetic process GO:0008610 179 0.042
positive regulation of protein phosphorylation GO:0001934 242 0.042
cellular ketone metabolic process GO:0042180 84 0.041
liver development GO:0001889 66 0.040
protein modification by small protein conjugation GO:0032446 187 0.039
response to organonitrogen compound GO:0010243 246 0.039
regulation of establishment of protein localization GO:0070201 181 0.038
adult behavior GO:0030534 135 0.038
dendrite development GO:0016358 115 0.037
organonitrogen compound catabolic process GO:1901565 264 0.037
regulation of protein serine threonine kinase activity GO:0071900 157 0.037
purine ribonucleoside metabolic process GO:0046128 241 0.037
ribonucleotide metabolic process GO:0009259 291 0.037
positive regulation of cell development GO:0010720 237 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
dephosphorylation GO:0016311 129 0.035
guanosine containing compound catabolic process GO:1901069 144 0.035
glycosyl compound catabolic process GO:1901658 206 0.035
carbohydrate derivative catabolic process GO:1901136 231 0.035
nucleoside phosphate catabolic process GO:1901292 222 0.034
organelle localization GO:0051640 179 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.034
purine nucleotide metabolic process GO:0006163 302 0.033
meiotic cell cycle GO:0051321 122 0.033
dna metabolic process GO:0006259 303 0.033
cellular lipid metabolic process GO:0044255 323 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
positive regulation of growth GO:0045927 104 0.032
regulation of cellular amine metabolic process GO:0033238 20 0.032
oocyte axis specification GO:0007309 2 0.032
amine metabolic process GO:0009308 45 0.031
purine ribonucleotide metabolic process GO:0009150 290 0.031
axonogenesis GO:0007409 274 0.031
syncytium formation GO:0006949 43 0.031
macromolecule catabolic process GO:0009057 281 0.031
protein modification by small protein conjugation or removal GO:0070647 207 0.031
modification dependent protein catabolic process GO:0019941 133 0.031
membrane tubulation GO:0097320 4 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
muscle cell differentiation GO:0042692 261 0.030
nucleobase containing small molecule metabolic process GO:0055086 352 0.030
compound eye development GO:0048749 1 0.029
ribose phosphate metabolic process GO:0019693 291 0.029
gland development GO:0048732 330 0.029
cytokine production GO:0001816 319 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
positive regulation of apoptotic process GO:0043065 217 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.028
oocyte construction GO:0007308 2 0.028
regulation of dendritic spine development GO:0060998 22 0.028
ruffle organization GO:0031529 16 0.028
purine containing compound metabolic process GO:0072521 311 0.028
purine nucleotide catabolic process GO:0006195 211 0.028
nucleotide metabolic process GO:0009117 332 0.028
aromatic compound catabolic process GO:0019439 286 0.028
protein catabolic process GO:0030163 221 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.027
positive regulation of actin filament polymerization GO:0030838 26 0.027
filopodium assembly GO:0046847 19 0.027
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.026
regulation of cytokine production GO:0001817 266 0.026
cellular nitrogen compound catabolic process GO:0044270 280 0.026
nucleoside triphosphate catabolic process GO:0009143 205 0.025
establishment of protein localization to membrane GO:0090150 54 0.025
rho protein signal transduction GO:0007266 32 0.025
cation transport GO:0006812 399 0.025
organophosphate catabolic process GO:0046434 232 0.025
stem cell differentiation GO:0048863 268 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.025
positive regulation of apoptotic signaling pathway GO:2001235 95 0.025
heterocycle catabolic process GO:0046700 280 0.025
cellular component assembly involved in morphogenesis GO:0010927 139 0.025
mitotic cell cycle process GO:1903047 159 0.024
nucleoside metabolic process GO:0009116 246 0.024
nucleotide catabolic process GO:0009166 217 0.024
protein ubiquitination GO:0016567 171 0.024
positive regulation of cell death GO:0010942 224 0.024
striated muscle tissue development GO:0014706 293 0.024
response to peptide hormone GO:0043434 127 0.024
cellular protein catabolic process GO:0044257 155 0.023
endocytosis GO:0006897 168 0.023
respiratory tube development GO:0030323 167 0.023
gtp metabolic process GO:0046039 144 0.023
purine nucleoside triphosphate catabolic process GO:0009146 203 0.023
ribonucleoside catabolic process GO:0042454 206 0.023
mitotic cell cycle GO:0000278 195 0.023
organonitrogen compound biosynthetic process GO:1901566 192 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
muscle system process GO:0003012 141 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.022
organelle assembly GO:0070925 177 0.022
regulation of hydrolase activity GO:0051336 246 0.022
microtubule based process GO:0007017 236 0.022
cellular response to organonitrogen compound GO:0071417 145 0.022
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.021
hepaticobiliary system development GO:0061008 67 0.021
nucleoside catabolic process GO:0009164 206 0.021
respiratory system development GO:0060541 190 0.021
oxidation reduction process GO:0055114 342 0.021
cilium morphogenesis GO:0060271 102 0.021
negative regulation of protein phosphorylation GO:0001933 126 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
cellularization GO:0007349 1 0.021
cytoplasmic transport GO:0016482 234 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
regulation of gtp catabolic process GO:0033124 113 0.021
positive regulation of mapk cascade GO:0043410 170 0.021
retrograde transport endosome to golgi GO:0042147 2 0.021
establishment of organelle localization GO:0051656 122 0.021
glycosyl compound metabolic process GO:1901657 246 0.020
circadian regulation of gene expression GO:0032922 48 0.020
regulation of nucleoside metabolic process GO:0009118 130 0.020
mitochondrion organization GO:0007005 134 0.020
response to lipopolysaccharide GO:0032496 128 0.020
regulation of cell cycle GO:0051726 281 0.020
regulation of establishment of protein localization to plasma membrane GO:0090003 12 0.020
guanosine containing compound metabolic process GO:1901068 144 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
skeletal system development GO:0001501 356 0.020
intracellular protein transport GO:0006886 204 0.019
synaptic transmission GO:0007268 329 0.019
protein localization to cell junction GO:1902414 3 0.019
embryonic organ morphogenesis GO:0048562 276 0.019
transmembrane transport GO:0055085 412 0.019
phospholipid biosynthetic process GO:0008654 36 0.019
negative regulation of protein modification process GO:0031400 163 0.019
regulation of cell projection assembly GO:0060491 38 0.018
dendritic spine development GO:0060996 30 0.018
regulation of system process GO:0044057 200 0.018
regulation of cell motility GO:2000145 236 0.018
establishment of synaptic vesicle localization GO:0097480 57 0.018
positive regulation of protein localization to plasma membrane GO:1903078 7 0.018
response to oxidative stress GO:0006979 123 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
sensory perception GO:0007600 245 0.017
primary neural tube formation GO:0014020 95 0.017
regulation of cell cycle process GO:0010564 160 0.017
synaptic vesicle localization GO:0097479 59 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
positive regulation of transferase activity GO:0051347 167 0.017
cell adhesion GO:0007155 329 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
ion transmembrane transport GO:0034220 361 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
modification dependent macromolecule catabolic process GO:0043632 133 0.017
cellular homeostasis GO:0019725 240 0.017
locomotory behavior GO:0007626 195 0.017
regulation of secretion by cell GO:1903530 249 0.017
histone modification GO:0016570 159 0.016
nitrogen compound transport GO:0071705 271 0.016
wnt signaling pathway GO:0016055 188 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
regulation of transferase activity GO:0051338 263 0.016
small molecule biosynthetic process GO:0044283 132 0.016
negative regulation of nervous system development GO:0051961 156 0.016
glycerolipid biosynthetic process GO:0045017 50 0.016
digestive tract development GO:0048565 190 0.016
negative regulation of molecular function GO:0044092 258 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
negative regulation of synapse assembly GO:0051964 3 0.016
synaptic vesicle transport GO:0048489 57 0.016
positive regulation of nervous system development GO:0051962 221 0.016
microtubule cytoskeleton organization GO:0000226 157 0.016
regulation of proteolysis GO:0030162 164 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
purine containing compound catabolic process GO:0072523 213 0.015
muscle tissue development GO:0060537 308 0.015
regulation of membrane potential GO:0042391 192 0.015
circulatory system process GO:0003013 197 0.015
asymmetric stem cell division GO:0098722 3 0.015
skeletal system morphogenesis GO:0048705 203 0.015
response to acid chemical GO:0001101 111 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
cation transmembrane transport GO:0098655 266 0.015
rab protein signal transduction GO:0032482 1 0.015
blood circulation GO:0008015 195 0.015
syncytium formation by plasma membrane fusion GO:0000768 42 0.015
spermatid differentiation GO:0048515 115 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
immune effector process GO:0002252 321 0.015
midgut development GO:0007494 4 0.015
regulation of map kinase activity GO:0043405 120 0.014
regulation of filopodium assembly GO:0051489 13 0.014
extracellular matrix organization GO:0030198 147 0.014
protein oligomerization GO:0051259 67 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
endomembrane system organization GO:0010256 147 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.014
innate immune response GO:0045087 157 0.014
hepatocyte apoptotic process GO:0097284 11 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
cell growth GO:0016049 130 0.014
negative regulation of cytokine production GO:0001818 84 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
lateral inhibition GO:0046331 1 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
muscle contraction GO:0006936 101 0.014
regulation of protein catabolic process GO:0042176 108 0.014
defecation GO:0030421 1 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
chemotaxis GO:0006935 247 0.014
regulation of jnk cascade GO:0046328 62 0.014
gtp catabolic process GO:0006184 143 0.014
regulation of defense response GO:0031347 233 0.014
multicellular organism growth GO:0035264 161 0.014
cation homeostasis GO:0055080 212 0.014
circadian rhythm GO:0007623 114 0.014
glycerolipid metabolic process GO:0046486 122 0.014
mapk cascade GO:0000165 281 0.014
forebrain development GO:0030900 302 0.014
glycerophospholipid metabolic process GO:0006650 71 0.014
macromolecule methylation GO:0043414 120 0.014
cellular chemical homeostasis GO:0055082 215 0.014
multicellular organismal homeostasis GO:0048871 164 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
regionalization GO:0003002 337 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
positive regulation of gtp catabolic process GO:0033126 85 0.013
neuron death GO:0070997 154 0.013
developmental maturation GO:0021700 193 0.013
camera type eye development GO:0043010 266 0.013
regulation of cell migration GO:0030334 219 0.013
ossification GO:0001503 216 0.013
asymmetric neuroblast division GO:0055059 1 0.013
positive regulation of kinase activity GO:0033674 155 0.013
protein maturation GO:0051604 176 0.013
organic acid biosynthetic process GO:0016053 86 0.013
rhythmic process GO:0048511 174 0.013
regulation of ras gtpase activity GO:0032318 88 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.013
homeostasis of number of cells GO:0048872 210 0.013
covalent chromatin modification GO:0016569 163 0.013
cell substrate adhesion GO:0031589 130 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
response to growth factor GO:0070848 198 0.013
positive regulation of map kinase activity GO:0043406 84 0.013
establishment of protein localization to plasma membrane GO:0090002 34 0.013
protein targeting GO:0006605 143 0.013
proteasomal protein catabolic process GO:0010498 98 0.013
regulation of multi organism process GO:0043900 111 0.013
ameboidal type cell migration GO:0001667 128 0.013
nuclear transport GO:0051169 139 0.013
peptidyl amino acid modification GO:0018193 336 0.013
extracellular structure organization GO:0043062 148 0.012
regulation of cell size GO:0008361 72 0.012
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.012
negative regulation of dna replication GO:0008156 4 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
cytokinetic process GO:0032506 2 0.012
protein localization to nucleus GO:0034504 121 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
protein import GO:0017038 101 0.012
t cell activation GO:0042110 289 0.012
stress activated mapk cascade GO:0051403 80 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
myosin filament assembly GO:0031034 2 0.012
multicellular organismal signaling GO:0035637 91 0.012
myeloid cell differentiation GO:0030099 233 0.012
organic anion transport GO:0015711 137 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
regulation of stress activated mapk cascade GO:0032872 69 0.012
establishment of epithelial cell polarity GO:0090162 10 0.012
phospholipid metabolic process GO:0006644 87 0.012
inflammatory response GO:0006954 244 0.012
learning GO:0007612 98 0.012
angiogenesis GO:0001525 201 0.012
spermatid development GO:0007286 108 0.012
cell cell junction organization GO:0045216 72 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
cell fate commitment GO:0045165 210 0.012
myeloid cell apoptotic process GO:0033028 22 0.012
antimicrobial peptide production GO:0002775 2 0.012
anion transport GO:0006820 177 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
response to peptide GO:1901652 136 0.011
pharynx development GO:0060465 1 0.011
neural tube development GO:0021915 160 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
dna endoreduplication GO:0042023 4 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
cognition GO:0050890 149 0.011
behavioral response to ethanol GO:0048149 8 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.011
regulation of cell activation GO:0050865 289 0.011
protein processing GO:0016485 163 0.011
stem cell development GO:0048864 219 0.011
epithelial cell development GO:0002064 159 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
regulation of antimicrobial peptide production GO:0002784 1 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
negative regulation of cell activation GO:0050866 111 0.011
neural precursor cell proliferation GO:0061351 121 0.011
response to light stimulus GO:0009416 135 0.011
positive regulation of cell projection organization GO:0031346 95 0.011
tissue homeostasis GO:0001894 115 0.011
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 11 0.011
cellular response to lipid GO:0071396 145 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
negative regulation of immune system process GO:0002683 209 0.011
response to inorganic substance GO:0010035 96 0.011
cilium assembly GO:0042384 81 0.011
single organism nuclear import GO:1902593 95 0.011
habituation GO:0046959 3 0.011
meiotic cytokinesis GO:0033206 5 0.011
muscle adaptation GO:0043500 39 0.011
fat cell differentiation GO:0045444 160 0.011
metal ion homeostasis GO:0055065 189 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
digestive system development GO:0055123 200 0.011
leukocyte differentiation GO:0002521 342 0.011
lymphocyte differentiation GO:0030098 242 0.011
bone development GO:0060348 120 0.010
sensory organ morphogenesis GO:0090596 242 0.010
anatomical structure homeostasis GO:0060249 145 0.010
cellular ion homeostasis GO:0006873 165 0.010
positive regulation of cell cycle process GO:0090068 61 0.010
transmission of nerve impulse GO:0019226 76 0.010
regulation of secretion GO:0051046 274 0.010
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.010
purine ribonucleoside catabolic process GO:0046130 205 0.010
mrna splicing via spliceosome GO:0000398 43 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
regulation of cell adhesion GO:0030155 154 0.010
regulation of cellular protein catabolic process GO:1903362 61 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
regulation of canonical wnt signaling pathway GO:0060828 82 0.010
regulation of endocytosis GO:0030100 69 0.010
negative regulation of wnt signaling pathway GO:0030178 73 0.010
vesicle localization GO:0051648 86 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
interleukin 8 production GO:0032637 4 0.010
maintenance of location GO:0051235 89 0.010
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.010
cellular response to biotic stimulus GO:0071216 92 0.010
b cell activation GO:0042113 161 0.010

Tjap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
musculoskeletal system disease DOID:17 0 0.028
neuromuscular disease DOID:440 0 0.017
neuropathy DOID:870 0 0.017
immune system disease DOID:2914 0 0.013
connective tissue disease DOID:65 0 0.013
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011
sensory system disease DOID:0050155 0 0.011
bone disease DOID:0080001 0 0.011
hematopoietic system disease DOID:74 0 0.011