Mus musculus

147 known processes

Tlr9

toll-like receptor 9

Tlr9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of defense response GO:0031349 124 0.269
Mouse Fly
cytokine production GO:0001816 319 0.228
regulation of cell activation GO:0050865 289 0.205
immune response activating signal transduction GO:0002757 116 0.182
Mouse
defense response to other organism GO:0098542 197 0.172
activation of innate immune response GO:0002218 56 0.170
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.162
cellular chemical homeostasis GO:0055082 215 0.161
anatomical structure homeostasis GO:0060249 145 0.151
regulation of cellular amino acid metabolic process GO:0006521 5 0.145
positive regulation of cell activation GO:0050867 158 0.145
positive regulation of cytokine production GO:0001819 174 0.144
myeloid cell differentiation GO:0030099 233 0.136
leukocyte migration GO:0050900 124 0.134
inflammatory response GO:0006954 244 0.126
homeostasis of number of cells GO:0048872 210 0.125
cation transport GO:0006812 399 0.107
myeloid leukocyte activation GO:0002274 83 0.105
cellular amine metabolic process GO:0044106 44 0.103
organic anion transport GO:0015711 137 0.102
regulation of lymphocyte activation GO:0051249 240 0.098
regulation of homeostatic process GO:0032844 182 0.097
cellular ketone metabolic process GO:0042180 84 0.095
multicellular organismal homeostasis GO:0048871 164 0.091
divalent inorganic cation homeostasis GO:0072507 138 0.090
tissue homeostasis GO:0001894 115 0.090
cellular response to lipid GO:0071396 145 0.089
immune response regulating signaling pathway GO:0002764 125 0.083
Mouse
action potential GO:0001508 78 0.083
regulation of ion transport GO:0043269 215 0.082
interferon gamma production GO:0032609 67 0.081
heterocycle catabolic process GO:0046700 280 0.079
regulation of inflammatory response GO:0050727 147 0.079
regulation of membrane potential GO:0042391 192 0.079
nucleobase containing small molecule metabolic process GO:0055086 352 0.079
calcium ion homeostasis GO:0055074 127 0.078
cellular response to cytokine stimulus GO:0071345 189 0.078
b cell proliferation GO:0042100 53 0.078
multicellular organismal signaling GO:0035637 91 0.076
cellular calcium ion homeostasis GO:0006874 119 0.076
negative regulation of inflammatory response GO:0050728 61 0.075
regulation of cytokine production GO:0001817 266 0.074
lymphocyte proliferation GO:0046651 164 0.073
calcium ion transport GO:0006816 159 0.070
reactive oxygen species metabolic process GO:0072593 84 0.069
sequestering of calcium ion GO:0051208 18 0.069
leukocyte proliferation GO:0070661 172 0.068
t cell activation GO:0042110 289 0.068
negative regulation of homeostatic process GO:0032845 71 0.066
b cell activation GO:0042113 161 0.065
cellular amino acid metabolic process GO:0006520 103 0.065
cellular response to biotic stimulus GO:0071216 92 0.064
negative regulation of defense response GO:0031348 77 0.063
amine metabolic process GO:0009308 45 0.063
regulation of transferase activity GO:0051338 263 0.063
regulation of body fluid levels GO:0050878 162 0.062
response to lipopolysaccharide GO:0032496 128 0.062
positive regulation of lymphocyte activation GO:0051251 140 0.061
response to organic cyclic compound GO:0014070 198 0.061
Mouse
positive regulation of protein modification process GO:0031401 299 0.060
anion transport GO:0006820 177 0.060
regulation of cellular amine metabolic process GO:0033238 20 0.060
cellular ion homeostasis GO:0006873 165 0.058
regulation of cellular ketone metabolic process GO:0010565 66 0.057
regulation of innate immune response GO:0045088 91 0.057
Mouse
skin development GO:0043588 220 0.057
negative regulation of protein metabolic process GO:0051248 282 0.056
epidermis development GO:0008544 187 0.055
divalent metal ion transport GO:0070838 172 0.055
negative regulation of protein modification process GO:0031400 163 0.055
striated muscle contraction GO:0006941 45 0.055
cellular metal ion homeostasis GO:0006875 151 0.054
positive regulation of cytokine biosynthetic process GO:0042108 40 0.054
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.054
regulation of leukocyte proliferation GO:0070663 121 0.053
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.053
Mouse
response to interleukin 12 GO:0070671 2 0.053
purine nucleotide catabolic process GO:0006195 211 0.053
defense response to virus GO:0051607 68 0.053
interferon beta biosynthetic process GO:0045350 4 0.053
positive regulation of immune effector process GO:0002699 107 0.053
Fly
regulation of interferon beta biosynthetic process GO:0045357 4 0.051
cytokine mediated signaling pathway GO:0019221 115 0.051
nucleotide metabolic process GO:0009117 332 0.051
metal ion homeostasis GO:0055065 189 0.050
cytosolic calcium ion transport GO:0060401 48 0.049
regulation of b cell activation GO:0050864 81 0.049
divalent inorganic cation transport GO:0072511 178 0.048
positive regulation of b cell proliferation GO:0030890 24 0.048
multicellular organism growth GO:0035264 161 0.047
response to molecule of bacterial origin GO:0002237 143 0.047
interleukin 18 production GO:0032621 4 0.046
nucleoside phosphate metabolic process GO:0006753 338 0.046
positive regulation of apoptotic process GO:0043065 217 0.046
regulation of cell migration GO:0030334 219 0.046
regulation of cellular catabolic process GO:0031329 242 0.045
Fly
regulation of intracellular transport GO:0032386 159 0.045
protein modification by small protein conjugation or removal GO:0070647 207 0.045
cation homeostasis GO:0055080 212 0.045
transmembrane transport GO:0055085 412 0.045
negative regulation of immune system process GO:0002683 209 0.045
maintenance of location GO:0051235 89 0.044
nucleoside triphosphate metabolic process GO:0009141 230 0.044
positive regulation of leukocyte differentiation GO:1902107 86 0.043
protein modification by small protein conjugation GO:0032446 187 0.043
detection of molecule of bacterial origin GO:0032490 2 0.042
organic acid transport GO:0015849 101 0.042
regulation of response to wounding GO:1903034 189 0.041
intestinal epithelial structure maintenance GO:0060729 4 0.041
regulation of leukocyte differentiation GO:1902105 159 0.041
chemotaxis GO:0006935 247 0.041
Fly
activation of mapk activity GO:0000187 59 0.041
regulation of b cell proliferation GO:0030888 39 0.041
regulation of map kinase activity GO:0043405 120 0.041
response to organonitrogen compound GO:0010243 246 0.041
myeloid leukocyte differentiation GO:0002573 119 0.041
positive regulation of interferon alpha production GO:0032727 4 0.041
Mouse
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.041
regulation of interleukin 8 production GO:0032677 3 0.041
membrane organization GO:0061024 245 0.040
positive regulation of t cell activation GO:0050870 101 0.040
ribonucleoside metabolic process GO:0009119 245 0.040
stem cell differentiation GO:0048863 268 0.040
small gtpase mediated signal transduction GO:0007264 97 0.040
cytokine biosynthetic process GO:0042089 68 0.039
Mouse
regionalization GO:0003002 337 0.039
Fly
regulation of ion homeostasis GO:2000021 64 0.038
stress activated protein kinase signaling cascade GO:0031098 81 0.038
Mouse
skeletal muscle organ development GO:0060538 163 0.038
transmission of nerve impulse GO:0019226 76 0.037
aromatic compound catabolic process GO:0019439 286 0.037
glycosyl compound catabolic process GO:1901658 206 0.037
transepithelial chloride transport GO:0030321 4 0.037
cellular nitrogen compound catabolic process GO:0044270 280 0.037
positive regulation of secretion GO:0051047 130 0.036
ribose phosphate metabolic process GO:0019693 291 0.036
i kappab kinase nf kappab signaling GO:0007249 85 0.036
Mouse
positive regulation of lymphocyte proliferation GO:0050671 70 0.036
nucleoside metabolic process GO:0009116 246 0.035
organic cyclic compound catabolic process GO:1901361 295 0.035
purine nucleoside metabolic process GO:0042278 241 0.035
negative regulation of cellular amine metabolic process GO:0033239 1 0.035
regulation of tumor necrosis factor production GO:0032680 49 0.035
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.035
positive regulation of leukocyte proliferation GO:0070665 73 0.035
regulation of reactive oxygen species metabolic process GO:2000377 40 0.035
cytosolic calcium ion homeostasis GO:0051480 70 0.034
regulation of system process GO:0044057 200 0.034
glycoprotein metabolic process GO:0009100 116 0.034
Fly
peptidyl amino acid modification GO:0018193 336 0.034
protein secretion GO:0009306 111 0.034
sequestering of metal ion GO:0051238 19 0.034
glycosyl compound metabolic process GO:1901657 246 0.034
cellular homeostasis GO:0019725 240 0.034
regulation of secretion by cell GO:1903530 249 0.033
regulation of protein localization GO:0032880 231 0.033
positive regulation of ion transport GO:0043270 65 0.033
regulation of interleukin 1 production GO:0032652 26 0.033
positive regulation of interleukin 8 production GO:0032757 2 0.033
striated muscle tissue development GO:0014706 293 0.033
microtubule cytoskeleton organization GO:0000226 157 0.032
positive regulation of programmed cell death GO:0043068 218 0.032
negative regulation of cellular protein metabolic process GO:0032269 247 0.032
carbohydrate derivative biosynthetic process GO:1901137 183 0.031
Fly
immune effector process GO:0002252 321 0.031
intracellular protein transport GO:0006886 204 0.031
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.031
peptidyl tyrosine phosphorylation GO:0018108 143 0.031
carboxylic acid transport GO:0046942 100 0.031
purine nucleotide metabolic process GO:0006163 302 0.030
innate immune response GO:0045087 157 0.030
Mouse Fly
posttranscriptional regulation of gene expression GO:0010608 155 0.030
epithelial cell development GO:0002064 159 0.030
epithelial cell proliferation GO:0050673 174 0.030
cytokine secretion GO:0050663 72 0.030
regulation of acute inflammatory response GO:0002673 27 0.030
camera type eye development GO:0043010 266 0.030
positive regulation of map kinase activity GO:0043406 84 0.029
regulation of erk1 and erk2 cascade GO:0070372 71 0.029
regulation of calcium ion transport GO:0051924 69 0.029
protein ubiquitination GO:0016567 171 0.029
macromolecule catabolic process GO:0009057 281 0.029
negative regulation of cytokine production GO:0001818 84 0.029
asymmetric stem cell division GO:0098722 3 0.028
ion transmembrane transport GO:0034220 361 0.028
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.028
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.028
epithelial tube morphogenesis GO:0060562 303 0.028
response to radiation GO:0009314 165 0.028
inorganic cation transmembrane transport GO:0098662 207 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.028
positive regulation of homeostatic process GO:0032846 64 0.027
morphogenesis of a branching epithelium GO:0061138 193 0.027
endomembrane system organization GO:0010256 147 0.027
organelle localization GO:0051640 179 0.026
rho protein signal transduction GO:0007266 32 0.026
response to light stimulus GO:0009416 135 0.026
organelle assembly GO:0070925 177 0.026
organic hydroxy compound transport GO:0015850 93 0.025
regulation of cellular component biogenesis GO:0044087 181 0.025
positive regulation of interleukin 18 production GO:0032741 2 0.025
cellular response to external stimulus GO:0071496 88 0.025
innate immune response activating signal transduction GO:0002758 50 0.025
Mouse
ribonucleotide metabolic process GO:0009259 291 0.025
lymphocyte differentiation GO:0030098 242 0.025
regulation of protein secretion GO:0050708 82 0.025
regulation of protein serine threonine kinase activity GO:0071900 157 0.025
sensory perception GO:0007600 245 0.024
negative regulation of response to wounding GO:1903035 77 0.024
regulation of cytokine secretion GO:0050707 61 0.024
regulation of organelle organization GO:0033043 289 0.024
mapk cascade GO:0000165 281 0.024
Mouse
muscle tissue development GO:0060537 308 0.024
transdifferentiation GO:0060290 1 0.024
spermatid development GO:0007286 108 0.024
establishment of endothelial blood brain barrier GO:0014045 3 0.024
gland development GO:0048732 330 0.024
muscle contraction GO:0006936 101 0.024
positive regulation of cell development GO:0010720 237 0.024
positive regulation of interferon beta production GO:0032728 8 0.023
microtubule based process GO:0007017 236 0.023
positive regulation of protein kinase activity GO:0045860 144 0.023
ras protein signal transduction GO:0007265 77 0.023
positive regulation of jnk cascade GO:0046330 46 0.023
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.023
t cell proliferation GO:0042098 120 0.023
cell activation involved in immune response GO:0002263 126 0.023
interleukin 8 production GO:0032637 4 0.023
regulation of protein transport GO:0051223 163 0.023
regulation of protein kinase activity GO:0045859 232 0.023
morphogenesis of a branching structure GO:0001763 203 0.022
positive regulation of stress activated mapk cascade GO:0032874 48 0.022
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
cation transmembrane transport GO:0098655 266 0.022
compound eye development GO:0048749 1 0.022
response to bacterial lipoprotein GO:0032493 4 0.022
developmental maturation GO:0021700 193 0.022
positive regulation of interferon beta biosynthetic process GO:0045359 3 0.022
amino acid transport GO:0006865 61 0.022
monocarboxylic acid metabolic process GO:0032787 191 0.022
lipid localization GO:0010876 126 0.022
positive regulation of cell death GO:0010942 224 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
regulation of lymphocyte mediated immunity GO:0002706 84 0.022
male gamete generation GO:0048232 285 0.021
positive regulation of protein transport GO:0051222 93 0.021
positive regulation of keratinocyte proliferation GO:0010838 4 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.021
regulation of lymphocyte proliferation GO:0050670 117 0.021
methylation GO:0032259 134 0.021
cellular response to abiotic stimulus GO:0071214 56 0.021
regulation of interleukin 18 production GO:0032661 3 0.021
nephron epithelium development GO:0072009 92 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
regulation of cytokine biosynthetic process GO:0042035 59 0.021
Mouse
positive regulation of secretion by cell GO:1903532 114 0.021
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.021
defense response to gram positive bacterium GO:0050830 50 0.021
protein catabolic process GO:0030163 221 0.021
cellular divalent inorganic cation homeostasis GO:0072503 127 0.021
erk1 and erk2 cascade GO:0070371 77 0.021
nitrogen compound transport GO:0071705 271 0.021
dna metabolic process GO:0006259 303 0.021
stress activated mapk cascade GO:0051403 80 0.020
Mouse
purine nucleoside catabolic process GO:0006152 205 0.020
regulation of t cell activation GO:0050863 170 0.020
positive regulation of interleukin 6 production GO:0032755 37 0.020
negative regulation of phosphorylation GO:0042326 166 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
positive regulation of interleukin 1 secretion GO:0050716 14 0.020
second messenger mediated signaling GO:0019932 73 0.020
immunoglobulin production GO:0002377 73 0.020
ossification GO:0001503 216 0.020
cellular macromolecule catabolic process GO:0044265 206 0.020
regulation of muscle system process GO:0090257 80 0.020
histone modification GO:0016570 159 0.020
regulation of organ morphogenesis GO:2000027 144 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
cellular response to peptidoglycan GO:0071224 4 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
regulation of defense response GO:0031347 233 0.019
calcium mediated signaling GO:0019722 46 0.019
positive regulation of inflammatory response GO:0050729 47 0.019
circulatory system process GO:0003013 197 0.019
synaptic transmission GO:0007268 329 0.019
positive regulation of cell migration GO:0030335 109 0.019
axonogenesis GO:0007409 274 0.019
regulation of epidermis development GO:0045682 33 0.019
sclerotome development GO:0061056 4 0.019
regulation of chemokine production GO:0032642 30 0.019
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.018
lymphocyte mediated immunity GO:0002449 139 0.018
positive regulation of myeloid cell differentiation GO:0045639 43 0.018
regulation of interleukin 6 production GO:0032675 55 0.018
apoptotic signaling pathway GO:0097190 306 0.018
response to host GO:0075136 3 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
regulation of actin filament based process GO:0032970 99 0.018
cell type specific apoptotic process GO:0097285 268 0.018
wnt signaling pathway GO:0016055 188 0.018
regulation of angiogenesis GO:0045765 81 0.018
negative regulation of leukocyte proliferation GO:0070664 46 0.018
synapse organization GO:0050808 125 0.018
Fly
purine containing compound catabolic process GO:0072523 213 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
positive regulation of thymocyte migration GO:2000412 2 0.018
organophosphate catabolic process GO:0046434 232 0.018
lateral inhibition GO:0046331 1 0.018
regulation of fat cell differentiation GO:0045598 81 0.018
regulation of neural retina development GO:0061074 3 0.018
cellular protein catabolic process GO:0044257 155 0.018
regulation of cell motility GO:2000145 236 0.018
muscle fiber development GO:0048747 76 0.018
positive regulation of t cell differentiation GO:0045582 52 0.017
translation GO:0006412 93 0.017
positive regulation of glutamate secretion GO:0014049 2 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
positive regulation of innate immune response GO:0045089 80 0.017
Mouse
production of molecular mediator of immune response GO:0002440 103 0.017
Fly
ribonucleoside monophosphate metabolic process GO:0009161 80 0.017
interleukin 10 production GO:0032613 23 0.017
regulation of leukocyte mediated immunity GO:0002703 104 0.017
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.017
regulation of myeloid leukocyte differentiation GO:0002761 58 0.017
interleukin 10 secretion GO:0072608 4 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
muscle cell development GO:0055001 133 0.017
regulation of translation GO:0006417 71 0.017
protein acylation GO:0043543 64 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
blood vessel morphogenesis GO:0048514 285 0.017
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.017
chloride transport GO:0006821 32 0.017
heart contraction GO:0060047 93 0.016
angiogenesis GO:0001525 201 0.016
circadian temperature homeostasis GO:0060086 2 0.016
tumor necrosis factor production GO:0032640 50 0.016
cytoplasmic transport GO:0016482 234 0.016
regulation of neuron differentiation GO:0045664 281 0.016
negative regulation of phagocytosis GO:0050765 4 0.016
germ line stem cell division GO:0042078 2 0.016
negative regulation of transferase activity GO:0051348 85 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
regulation of mapk cascade GO:0043408 248 0.016
Mouse
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
positive regulation of type i interferon production GO:0032481 14 0.016
leukocyte mediated immunity GO:0002443 174 0.016
stem cell maintenance GO:0019827 130 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
negative regulation of lymphocyte proliferation GO:0050672 45 0.016
wound healing GO:0042060 157 0.016
regulation of t cell proliferation GO:0042129 92 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
positive regulation of interferon gamma production GO:0032729 39 0.016
sensory perception of pain GO:0019233 47 0.016
lens development in camera type eye GO:0002088 62 0.015
regulation of metal ion transport GO:0010959 106 0.015
positive regulation of transferase activity GO:0051347 167 0.015
glial cell apoptotic process GO:0034349 3 0.015
response to growth factor GO:0070848 198 0.015
Fly
endocytosis GO:0006897 168 0.015
chromatin organization GO:0006325 206 0.015
cardiac muscle contraction GO:0060048 32 0.015
ear development GO:0043583 200 0.015
gtp metabolic process GO:0046039 144 0.015
sensory perception of chemical stimulus GO:0007606 51 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
learning or memory GO:0007611 148 0.015
fatty acid metabolic process GO:0006631 121 0.015
regulation of blood circulation GO:1903522 93 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
protein localization to organelle GO:0033365 185 0.015
germ cell development GO:0007281 185 0.015
spermatogenesis GO:0007283 284 0.015
macrophage activation GO:0042116 27 0.015
regulation of interferon gamma production GO:0032649 57 0.015
regulation of kinase activity GO:0043549 249 0.015
heart process GO:0003015 94 0.015
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.015
regulation of odontogenesis GO:0042481 18 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
cell chemotaxis GO:0060326 81 0.014
forebrain development GO:0030900 302 0.014
fat cell differentiation GO:0045444 160 0.014
regulation of interleukin 23 production GO:0032667 2 0.014
interleukin 6 production GO:0032635 58 0.014
intracellular distribution of mitochondria GO:0048312 1 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
extracellular matrix organization GO:0030198 147 0.014
regulation of hormone levels GO:0010817 211 0.014
regulation of tissue remodeling GO:0034103 38 0.014
nuclear transport GO:0051169 139 0.014
regulation of transmembrane transport GO:0034762 128 0.014
regulation of retina development in camera type eye GO:1902866 3 0.014
heart morphogenesis GO:0003007 178 0.014
calcium ion transmembrane transport GO:0070588 85 0.014
nucleoside catabolic process GO:0009164 206 0.014
regulation of cell projection organization GO:0031344 206 0.014
response to acid chemical GO:0001101 111 0.014
leukocyte differentiation GO:0002521 342 0.014
hair follicle development GO:0001942 85 0.014
positive regulation of cytokine secretion GO:0050715 41 0.014
regulation of myeloid cell differentiation GO:0045637 96 0.014
negative regulation of cell activation GO:0050866 111 0.014
carbohydrate metabolic process GO:0005975 230 0.014
Fly
atp catabolic process GO:0006200 55 0.014
pancreatic pp cell differentiation GO:0003312 2 0.014
blood circulation GO:0008015 195 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
mitotic cell cycle GO:0000278 195 0.013
Fly
negative regulation of cellular component organization GO:0051129 194 0.013
jnk cascade GO:0007254 72 0.013
Mouse
antibiotic transport GO:0042891 1 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
Fly
positive regulation of leukocyte mediated immunity GO:0002705 70 0.013
regulation of secretion GO:0051046 274 0.013
regulation of striated muscle cell differentiation GO:0051153 81 0.013
neuron apoptotic process GO:0051402 142 0.013
negative regulation of immune effector process GO:0002698 55 0.013
interleukin 1 beta production GO:0032611 30 0.013
monocarboxylic acid transport GO:0015718 44 0.013
negative regulation of interleukin 10 secretion GO:2001180 2 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
exocytosis GO:0006887 121 0.013
myotube differentiation GO:0014902 105 0.013
neutrophil chemotaxis GO:0030593 36 0.013
defense response to bacterium GO:0042742 119 0.013
Worm Fly
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.013
visual behavior GO:0007632 45 0.013
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.013
positive regulation of t cell proliferation GO:0042102 52 0.013
regulation of protein kinase b signaling GO:0051896 56 0.013
negative regulation of molecular function GO:0044092 258 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
homeostasis of number of cells within a tissue GO:0048873 25 0.013
type i interferon production GO:0032606 29 0.013
positive regulation of gtp catabolic process GO:0033126 85 0.013
pancreatic a cell fate commitment GO:0003326 2 0.013
cell growth GO:0016049 130 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
regulation of cell cycle GO:0051726 281 0.013
positive regulation of b cell activation GO:0050871 49 0.012
negative regulation of t cell proliferation GO:0042130 38 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
peptidyl serine modification GO:0018209 83 0.012
serotonin production involved in inflammatory response GO:0002351 4 0.012
mature dendritic cell differentiation GO:0097029 3 0.012
hair cycle GO:0042633 90 0.012
cell adhesion GO:0007155 329 0.012
Fly
sensory perception of smell GO:0007608 26 0.012
negative regulation of myeloid cell differentiation GO:0045638 38 0.012
activation of immune response GO:0002253 138 0.012
Mouse
neutrophil migration GO:1990266 37 0.012
positive regulation of transcription via serum response element binding GO:0010735 1 0.012
receptor mediated endocytosis GO:0006898 51 0.012
pattern recognition receptor signaling pathway GO:0002221 47 0.012
Mouse
mitotic cell cycle process GO:1903047 159 0.012
Fly
regulation of chromosome organization GO:0033044 83 0.012
cognition GO:0050890 149 0.012
sodium ion transport GO:0006814 73 0.012
regulation of interleukin 1 beta production GO:0032651 25 0.012
positive regulation of osteoclast differentiation GO:0045672 15 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
activation of mapk activity involved in innate immune response GO:0035419 2 0.012
antigen receptor mediated signaling pathway GO:0050851 64 0.012
spermatid differentiation GO:0048515 115 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
myeloid leukocyte migration GO:0097529 57 0.012
actin cytoskeleton organization GO:0030036 220 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
leukocyte chemotaxis GO:0030595 69 0.012
regulation of hydrolase activity GO:0051336 246 0.012
mast cell activation GO:0045576 27 0.012
granulocyte migration GO:0097530 43 0.012
osteoclast differentiation GO:0030316 62 0.012
positive regulation of chemotaxis GO:0050921 38 0.012
b cell activation involved in immune response GO:0002312 50 0.012
negative regulation of protein transport GO:0051224 46 0.012
glial cell differentiation GO:0010001 131 0.012
learning GO:0007612 98 0.012
myeloid cell activation involved in immune response GO:0002275 34 0.012
regulation of calcium mediated signaling GO:0050848 19 0.012
serotonin secretion involved in inflammatory response GO:0002442 4 0.012

Tlr9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.019
cancer DOID:162 0 0.016
organ system cancer DOID:0050686 0 0.016
disease of anatomical entity DOID:7 0 0.015
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015
nervous system disease DOID:863 0 0.013
sensory system disease DOID:0050155 0 0.013
immune system disease DOID:2914 0 0.012