Mus musculus

78 known processes

Tnc

tenascin C

(Aliases: cytotactin,Hxb,MGC144209,MGC144208,TN-C,Ten,tenascin-C,TN,C130033P17Rik,AI528729)

Tnc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell matrix adhesion GO:0007160 68 0.549
Mouse
extracellular matrix organization GO:0030198 147 0.394
Mouse
cell substrate adhesion GO:0031589 130 0.384
Mouse
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.348
cell adhesion GO:0007155 329 0.346
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.341
response to amino acid GO:0043200 37 0.329
regulation of cell adhesion GO:0030155 154 0.319
Mouse
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.303
negative regulation of cell substrate adhesion GO:0010812 16 0.303
regulation of cell substrate adhesion GO:0010810 73 0.303
skeletal system morphogenesis GO:0048705 203 0.298
extracellular structure organization GO:0043062 148 0.290
Mouse
multicellular organismal homeostasis GO:0048871 164 0.277
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.276
negative regulation of cell adhesion GO:0007162 45 0.275
Mouse
cellular response to amino acid stimulus GO:0071230 29 0.251
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.246
regulation of sphingolipid biosynthetic process GO:0090153 1 0.237
fibrinolysis GO:0042730 3 0.234
response to growth factor GO:0070848 198 0.233
ossification GO:0001503 216 0.232
Human
proteoglycan metabolic process GO:0006029 38 0.228
wound healing GO:0042060 157 0.224
Mouse
ras protein signal transduction GO:0007265 77 0.219
negative regulation of cell migration GO:0030336 59 0.218
regulation of cell migration GO:0030334 219 0.213
appendage development GO:0048736 166 0.209
skeletal system development GO:0001501 356 0.205
rho protein signal transduction GO:0007266 32 0.199
response to fibroblast growth factor GO:0071774 47 0.195
cellular response to growth factor stimulus GO:0071363 197 0.195
muscle tissue development GO:0060537 308 0.187
cartilage condensation GO:0001502 18 0.183
response to organonitrogen compound GO:0010243 246 0.181
tissue homeostasis GO:0001894 115 0.181
synaptic transmission GO:0007268 329 0.177
Zebrafish Mouse
cartilage development GO:0051216 140 0.176
intussusceptive angiogenesis GO:0002041 2 0.175
single organismal cell cell adhesion GO:0016337 131 0.173
Mouse
regulation of cell motility GO:2000145 236 0.173
cellular response to acid chemical GO:0071229 68 0.166
response to transforming growth factor beta GO:0071559 88 0.165
chondrocyte differentiation GO:0002062 72 0.161
membrane lipid biosynthetic process GO:0046467 32 0.158
connective tissue development GO:0061448 179 0.152
negative regulation of cell motility GO:2000146 61 0.149
anatomical structure homeostasis GO:0060249 145 0.144
cellular response to organonitrogen compound GO:0071417 145 0.142
regulation of rho protein signal transduction GO:0035023 71 0.139
sphingolipid biosynthetic process GO:0030148 26 0.138
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.130
heart morphogenesis GO:0003007 178 0.121
regulation of ceramide biosynthetic process GO:2000303 1 0.121
striated muscle tissue development GO:0014706 293 0.119
blood vessel morphogenesis GO:0048514 285 0.119
regulation of apoptotic signaling pathway GO:2001233 197 0.115
small gtpase mediated signal transduction GO:0007264 97 0.114
aorta smooth muscle tissue morphogenesis GO:0060414 2 0.106
bone development GO:0060348 120 0.105
response to acid chemical GO:0001101 111 0.105
positive regulation of cell migration GO:0030335 109 0.105
regulation of proteolysis GO:0030162 164 0.105
Mouse
protein heterotrimerization GO:0070208 8 0.103
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.103
negative regulation of nervous system development GO:0051961 156 0.100
Zebrafish Mouse
digestive tract morphogenesis GO:0048546 147 0.095
cellular response to external stimulus GO:0071496 88 0.094
sensory perception GO:0007600 245 0.094
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.094
myeloid leukocyte migration GO:0097529 57 0.093
transmembrane transport GO:0055085 412 0.090
regulation of neuron migration GO:2001222 22 0.089
response to organic cyclic compound GO:0014070 198 0.088
sensory perception of sound GO:0007605 97 0.085
ceramide biosynthetic process GO:0046513 20 0.084
regulation of fibrinolysis GO:0051917 1 0.082
bone trabecula morphogenesis GO:0061430 12 0.082
inflammatory response GO:0006954 244 0.081
trabecula morphogenesis GO:0061383 40 0.081
positive regulation of rho protein signal transduction GO:0035025 7 0.081
engulfment of apoptotic cell GO:0043652 3 0.080
cardiac muscle tissue development GO:0048738 130 0.078
chondrocyte development GO:0002063 24 0.077
endochondral bone morphogenesis GO:0060350 50 0.075
bone morphogenesis GO:0060349 78 0.074
mapk cascade GO:0000165 281 0.073
Mouse
digestive tract development GO:0048565 190 0.072
single organism cell adhesion GO:0098602 156 0.072
Mouse
regulation of endopeptidase activity GO:0052548 89 0.071
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.071
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.070
regulation of mapk cascade GO:0043408 248 0.069
Mouse
collagen fibril organization GO:0030199 32 0.069
Mouse
regulation of peptidase activity GO:0052547 96 0.069
Mouse
sensory organ morphogenesis GO:0090596 242 0.067
cell adhesion mediated by integrin GO:0033627 18 0.067
apoptotic signaling pathway GO:0097190 306 0.066
sphingolipid metabolic process GO:0006665 45 0.066
positive regulation of sphingolipid biosynthetic process GO:0090154 1 0.066
bone resorption GO:0045453 38 0.064
organic acid transport GO:0015849 101 0.064
cell aggregation GO:0098743 18 0.064
glycoprotein metabolic process GO:0009100 116 0.064
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.063
protein oligomerization GO:0051259 67 0.060
skin development GO:0043588 220 0.060
regulation of blood coagulation GO:0030193 28 0.059
ion transmembrane transport GO:0034220 361 0.058
bone trabecula formation GO:0060346 9 0.058
macromolecule catabolic process GO:0009057 281 0.057
protein catabolic process GO:0030163 221 0.057
neuron migration GO:0001764 122 0.056
head morphogenesis GO:0060323 34 0.056
anion transport GO:0006820 177 0.056
regulation of eosinophil migration GO:2000416 2 0.055
chemotaxis GO:0006935 247 0.055
Zebrafish
negative regulation of cell development GO:0010721 169 0.055
Zebrafish Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.055
regulation of plasminogen activation GO:0010755 4 0.055
regulation of body fluid levels GO:0050878 162 0.054
ear development GO:0043583 200 0.053
digestive system development GO:0055123 200 0.052
carboxylic acid transport GO:0046942 100 0.052
positive regulation of cell adhesion GO:0045785 80 0.052
protein trimerization GO:0070206 13 0.051
negative regulation of molecular function GO:0044092 258 0.051
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.051
protein processing GO:0016485 163 0.050
negative regulation of intracellular signal transduction GO:1902532 167 0.050
reactive oxygen species metabolic process GO:0072593 84 0.048
protein maturation GO:0051604 176 0.047
negative regulation of cell proliferation GO:0008285 296 0.046
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.046
signal transduction in absence of ligand GO:0038034 55 0.046
endoderm development GO:0007492 45 0.045
positive regulation of response to wounding GO:1903036 66 0.044
Zebrafish
regulation of ras protein signal transduction GO:0046578 114 0.044
cell chemotaxis GO:0060326 81 0.044
negative regulation of apoptotic signaling pathway GO:2001234 104 0.044
cardiac chamber morphogenesis GO:0003206 93 0.044
pallium development GO:0021543 120 0.043
cellular lipid metabolic process GO:0044255 323 0.043
Mouse
regulation of coagulation GO:0050818 31 0.042
calcium ion transport GO:0006816 159 0.042
endodermal cell differentiation GO:0035987 14 0.042
cellular response to cytokine stimulus GO:0071345 189 0.042
replacement ossification GO:0036075 26 0.041
ear morphogenesis GO:0042471 118 0.041
regulation of ion transport GO:0043269 215 0.041
trabecula formation GO:0060343 24 0.041
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.041
face development GO:0060324 38 0.040
regulation of cell activation GO:0050865 289 0.040
integrin mediated signaling pathway GO:0007229 27 0.040
response to catecholamine GO:0071869 4 0.040
regulation of cellular component biogenesis GO:0044087 181 0.040
Zebrafish
lipid biosynthetic process GO:0008610 179 0.039
negative regulation of neuron migration GO:2001223 6 0.039
regulation of map kinase activity GO:0043405 120 0.039
Mouse
inner ear morphogenesis GO:0042472 101 0.039
positive regulation of protein phosphorylation GO:0001934 242 0.039
respiratory tube development GO:0030323 167 0.038
axonogenesis GO:0007409 274 0.038
Zebrafish Mouse
thymocyte migration GO:0072679 2 0.038
protein heterooligomerization GO:0051291 14 0.038
regulation of protein kinase activity GO:0045859 232 0.038
Mouse
membrane lipid metabolic process GO:0006643 53 0.038
regulation of organelle organization GO:0033043 289 0.038
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.038
ameboidal type cell migration GO:0001667 128 0.038
Zebrafish
positive regulation of cell motility GO:2000147 116 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
cellular ketone metabolic process GO:0042180 84 0.037
appendage morphogenesis GO:0035107 149 0.037
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.037
positive regulation of eosinophil migration GO:2000418 2 0.036
sensory perception of mechanical stimulus GO:0050954 107 0.036
activation of mapk activity involved in innate immune response GO:0035419 2 0.036
regulation of reactive oxygen species metabolic process GO:2000377 40 0.036
regulation of system process GO:0044057 200 0.036
Mouse
negative regulation of fibrinolysis GO:0051918 1 0.036
positive regulation of thymocyte migration GO:2000412 2 0.036
response to epidermal growth factor GO:0070849 4 0.036
cation transport GO:0006812 399 0.035
organic anion transport GO:0015711 137 0.035
oxidation reduction process GO:0055114 342 0.035
skeletal muscle organ development GO:0060538 163 0.035
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.035
positive regulation of map kinase activity GO:0043406 84 0.035
body morphogenesis GO:0010171 45 0.034
response to nitric oxide GO:0071731 4 0.033
endoderm formation GO:0001706 20 0.033
positive regulation of phospholipase activity GO:0010518 3 0.033
limb development GO:0060173 166 0.033
response to peptide hormone GO:0043434 127 0.032
cardiac chamber development GO:0003205 108 0.032
regulation of ossification GO:0030278 112 0.032
renal system development GO:0072001 225 0.032
fibril organization GO:0097435 2 0.032
Mouse
tendon development GO:0035989 6 0.032
positive regulation of cell substrate adhesion GO:0010811 47 0.032
negative regulation of coagulation GO:0050819 11 0.032
regulation of transmembrane transport GO:0034762 128 0.032
cardiac ventricle development GO:0003231 83 0.031
regulation of hemostasis GO:1900046 28 0.031
regulation of thymocyte migration GO:2000410 2 0.031
face morphogenesis GO:0060325 29 0.031
positive regulation of proteolysis GO:0045862 85 0.030
Mouse
regulation of ion transmembrane transport GO:0034765 119 0.030
leukocyte chemotaxis GO:0030595 69 0.030
membrane organization GO:0061024 245 0.030
cellular response to abiotic stimulus GO:0071214 56 0.030
response to peptide GO:1901652 136 0.029
angiogenesis GO:0001525 201 0.029
response to inorganic substance GO:0010035 96 0.029
formation of primary germ layer GO:0001704 77 0.029
negative regulation of blood vessel morphogenesis GO:2000181 25 0.029
divalent metal ion transport GO:0070838 172 0.029
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.029
negative regulation of peptidase activity GO:0010466 46 0.028
notochord development GO:0030903 20 0.028
fatty acid transmembrane transport GO:1902001 1 0.028
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.028
lipid transport GO:0006869 98 0.028
embryonic organ morphogenesis GO:0048562 276 0.028
multi multicellular organism process GO:0044706 109 0.028
regulation of cellular response to growth factor stimulus GO:0090287 82 0.027
cellular amine metabolic process GO:0044106 44 0.027
gastrulation GO:0007369 116 0.027
regulation of cytokine production GO:0001817 266 0.027
negative regulation of protein processing GO:0010955 79 0.027
endomembrane system organization GO:0010256 147 0.027
granulocyte migration GO:0097530 43 0.026
chondroblast differentiation GO:0060591 2 0.026
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
purine containing compound metabolic process GO:0072521 311 0.026
response to monosaccharide GO:0034284 67 0.026
eosinophil migration GO:0072677 3 0.026
leukocyte migration GO:0050900 124 0.026
ceramide metabolic process GO:0006672 31 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
response to extracellular stimulus GO:0009991 127 0.026
cellular chemical homeostasis GO:0055082 215 0.026
regulation of wound healing GO:0061041 40 0.026
regulation of lipid biosynthetic process GO:0046890 54 0.025
regulation of kinase activity GO:0043549 249 0.025
Mouse
second messenger mediated signaling GO:0019932 73 0.025
cerebral cortex development GO:0021987 86 0.025
negative regulation of protein metabolic process GO:0051248 282 0.025
purine ribonucleotide metabolic process GO:0009150 290 0.025
cellular response to hormone stimulus GO:0032870 150 0.025
cell cell adhesion GO:0098609 41 0.025
regulation of response to wounding GO:1903034 189 0.025
Zebrafish Mouse
regulation of leukocyte differentiation GO:1902105 159 0.025
divalent inorganic cation transport GO:0072511 178 0.025
regulation of neuron projection development GO:0010975 169 0.025
Zebrafish Mouse
cognition GO:0050890 149 0.025
Mouse
purine nucleotide metabolic process GO:0006163 302 0.025
cellular homeostasis GO:0019725 240 0.025
lung development GO:0030324 164 0.024
nucleoside phosphate metabolic process GO:0006753 338 0.024
actin filament organization GO:0007015 113 0.024
regulation of erk1 and erk2 cascade GO:0070372 71 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
organelle assembly GO:0070925 177 0.023
response to radiation GO:0009314 165 0.023
response to metal ion GO:0010038 47 0.023
cell recognition GO:0008037 83 0.023
Zebrafish
developmental maturation GO:0021700 193 0.023
muscle cell development GO:0055001 133 0.023
retinal blood vessel morphogenesis GO:0061304 3 0.023
tissue migration GO:0090130 68 0.023
negative regulation of vasculature development GO:1901343 26 0.023
cellular ion homeostasis GO:0006873 165 0.022
aminoglycan metabolic process GO:0006022 34 0.022
response to insulin GO:0032868 100 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
Zebrafish Mouse
positive regulation of cell development GO:0010720 237 0.022
Zebrafish Mouse
wound healing spreading of cells GO:0044319 8 0.022
anatomical structure maturation GO:0071695 49 0.022
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.022
positive regulation of defense response GO:0031349 124 0.022
regulation of lipid metabolic process GO:0019216 118 0.022
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.021
negative regulation of fatty acid transport GO:2000192 1 0.021
mononuclear cell migration GO:0071674 8 0.021
artery development GO:0060840 53 0.021
cellular response to nitric oxide GO:0071732 4 0.021
positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 12 0.021
zymogen activation GO:0031638 41 0.021
calcium ion homeostasis GO:0055074 127 0.021
positive regulation of cell death GO:0010942 224 0.021
monocarboxylic acid transport GO:0015718 44 0.021
regulation of homotypic cell cell adhesion GO:0034110 13 0.021
regulation of cytoskeleton organization GO:0051493 122 0.021
fat cell differentiation GO:0045444 160 0.020
positive regulation of mapk cascade GO:0043410 170 0.020
positive regulation of kinase activity GO:0033674 155 0.020
neuronal action potential GO:0019228 54 0.020
homeostasis of number of cells GO:0048872 210 0.020
synaptic transmission glutamatergic GO:0035249 36 0.020
Mouse
muscle contraction GO:0006936 101 0.020
muscle tissue morphogenesis GO:0060415 53 0.020
forebrain development GO:0030900 302 0.020
Mouse
negative regulation of endopeptidase activity GO:0010951 44 0.020
direct ossification GO:0036072 5 0.020
regulation of tissue remodeling GO:0034103 38 0.020
lipid localization GO:0010876 126 0.019
negative regulation of hemostasis GO:1900047 11 0.019
smooth muscle tissue development GO:0048745 22 0.019
defense response to other organism GO:0098542 197 0.019
fatty acid transport GO:0015908 28 0.019
translation GO:0006412 93 0.019
dendritic spine maintenance GO:0097062 4 0.019
negative regulation of protein maturation GO:1903318 79 0.019
aorta morphogenesis GO:0035909 22 0.019
biomineral tissue development GO:0031214 64 0.019
activation of mapk activity GO:0000187 59 0.019
regulation of translation GO:0006417 71 0.019
response to reactive oxygen species GO:0000302 56 0.018
response to drug GO:0042493 75 0.018
negative regulation of plasminogen activation GO:0010757 2 0.018
leukocyte cell cell adhesion GO:0007159 14 0.018
positive regulation of lipid biosynthetic process GO:0046889 18 0.018
cellular calcium ion homeostasis GO:0006874 119 0.018
developmental growth involved in morphogenesis GO:0060560 138 0.018
Zebrafish Mouse
actin cytoskeleton organization GO:0030036 220 0.018
endocytosis GO:0006897 168 0.018
epithelial to mesenchymal transition GO:0001837 47 0.018
cardiac muscle tissue morphogenesis GO:0055008 44 0.018
positive regulation of behavior GO:0048520 40 0.018
negative regulation of gastrulation GO:2000542 3 0.018
cell type specific apoptotic process GO:0097285 268 0.018
cellular component assembly involved in morphogenesis GO:0010927 139 0.018
regulation of cellular ketone metabolic process GO:0010565 66 0.018
cellular response to lipid GO:0071396 145 0.018
plasma membrane organization GO:0007009 90 0.017
renal system process GO:0003014 48 0.017
regulation of endodermal cell differentiation GO:1903224 2 0.017
phagocytosis GO:0006909 66 0.017
molting cycle GO:0042303 90 0.017
regulation of vasculature development GO:1901342 88 0.017
carbohydrate metabolic process GO:0005975 230 0.017
regulation of inflammatory response GO:0050727 147 0.017
regulation of angiogenesis GO:0045765 81 0.017
nucleotide metabolic process GO:0009117 332 0.017
positive regulation of macrophage chemotaxis GO:0010759 5 0.017
regulation of cysteine type endopeptidase activity GO:2000116 65 0.017
positive regulation of bone remodeling GO:0046852 13 0.017
mesodermal cell migration GO:0008078 4 0.016
cation homeostasis GO:0055080 212 0.016
organelle fission GO:0048285 170 0.016
regulation of bone resorption GO:0045124 24 0.016
regulation of homeostatic process GO:0032844 182 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.016
sequestering of calcium ion GO:0051208 18 0.016
positive regulation of hydrolase activity GO:0051345 148 0.016
Mouse
cellular protein complex assembly GO:0043623 116 0.016
tissue remodeling GO:0048771 102 0.016
negative regulation of blood coagulation GO:0030195 11 0.016
positive regulation of coagulation GO:0050820 13 0.016
elastic fiber assembly GO:0048251 4 0.016
endothelial cell apoptotic process GO:0072577 9 0.016
t cell activation GO:0042110 289 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
positive regulation of cell activation GO:0050867 158 0.016
positive regulation of neuron projection development GO:0010976 79 0.016
Zebrafish Mouse
negative regulation of hydrolase activity GO:0051346 71 0.016
immune effector process GO:0002252 321 0.016
development of primary female sexual characteristics GO:0046545 73 0.016
regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000307 1 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
regulation of membrane potential GO:0042391 192 0.015
cellular response to epidermal growth factor stimulus GO:0071364 4 0.015
positive regulation of monocyte chemotaxis GO:0090026 2 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
regulation of actin filament based process GO:0032970 99 0.015
negative regulation of smooth muscle cell migration GO:0014912 2 0.015
negative regulation of neuron death GO:1901215 98 0.015
metal ion homeostasis GO:0055065 189 0.015
regulation of protein maturation GO:1903317 96 0.015
regulation of anatomical structure size GO:0090066 178 0.015
Zebrafish Mouse
limb morphogenesis GO:0035108 149 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
positive regulation of ras protein signal transduction GO:0046579 13 0.015
otic vesicle development GO:0071599 14 0.015
membrane invagination GO:0010324 17 0.014
regulation of epithelial cell migration GO:0010632 35 0.014
telencephalon development GO:0021537 186 0.014
Mouse
cellular response to inorganic substance GO:0071241 37 0.014
regulation of monocyte chemotaxis GO:0090025 3 0.014
ventricular septum development GO:0003281 42 0.014
regulation of anion transport GO:0044070 27 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
cell junction organization GO:0034330 77 0.014
Mouse
negative regulation of angiogenesis GO:0016525 25 0.014
positive regulation of transferase activity GO:0051347 167 0.014
glycerolipid biosynthetic process GO:0045017 50 0.014
blood coagulation GO:0007596 76 0.014
extracellular matrix dependent thymocyte migration GO:0072680 1 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
regulation of lipid transport GO:0032368 36 0.014
erk1 and erk2 cascade GO:0070371 77 0.014
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
response to pain GO:0048265 26 0.014
regulation of chondrocyte differentiation GO:0032330 33 0.014
organ growth GO:0035265 117 0.014
cell cycle g1 s phase transition GO:0044843 57 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
regulation of cell projection organization GO:0031344 206 0.013
Zebrafish Mouse
response to nutrient levels GO:0031667 109 0.013
defense response to bacterium GO:0042742 119 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
striated muscle cell development GO:0055002 125 0.013
response to oxygen radical GO:0000305 16 0.013
negative regulation of proteolysis GO:0045861 74 0.013
negative regulation of immune system process GO:0002683 209 0.013
regulation of calcium ion transport GO:0051924 69 0.013
glucose homeostasis GO:0042593 128 0.013
growth plate cartilage development GO:0003417 14 0.013
embryonic skeletal system morphogenesis GO:0048704 91 0.013
negative regulation of wound healing GO:0061045 14 0.013
chondrocyte proliferation GO:0035988 6 0.013
positive regulation of homeostatic process GO:0032846 64 0.013
regulation of protein processing GO:0070613 96 0.013
steroid metabolic process GO:0008202 119 0.013
negative regulation of macrophage chemotaxis GO:0010760 1 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
positive regulation of cardiac muscle contraction GO:0060452 2 0.013
positive regulation of smooth muscle cell migration GO:0014911 4 0.013
peripheral nervous system axon regeneration GO:0014012 2 0.013
epithelium migration GO:0090132 63 0.013
positive regulation of cytokine production GO:0001819 174 0.012
myosin filament assembly GO:0031034 2 0.012
axon guidance GO:0007411 141 0.012
Zebrafish
regulation of t cell activation GO:0050863 170 0.012
detection of abiotic stimulus GO:0009582 60 0.012
regulation of protein catabolic process GO:0042176 108 0.012
protein secretion GO:0009306 111 0.012
circulatory system process GO:0003013 197 0.012
fibronectin dependent thymocyte migration GO:0072681 1 0.012
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.012
regulation of actin cytoskeleton organization GO:0032956 84 0.012
response to hyperoxia GO:0055093 2 0.012
nitrogen compound transport GO:0071705 271 0.012
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.012
oocyte axis specification GO:0007309 2 0.012
female gonad development GO:0008585 71 0.012
positive regulation of chemotaxis GO:0050921 38 0.012
protein localization to membrane GO:0072657 108 0.012
extracellular fibril organization GO:0043206 2 0.012
Mouse
regulation of removal of superoxide radicals GO:2000121 4 0.012
mucopolysaccharide metabolic process GO:1903510 25 0.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.012
epithelial cell migration GO:0010631 63 0.012
regulation of metal ion transport GO:0010959 106 0.012
adult behavior GO:0030534 135 0.012
regulation of fibronectin dependent thymocyte migration GO:2000413 1 0.012
regulation of action potential GO:0098900 4 0.011
protein kinase b signaling GO:0043491 74 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
keratinocyte migration GO:0051546 3 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
limb bud formation GO:0060174 10 0.011
cellular protein catabolic process GO:0044257 155 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
astrocyte cell migration GO:0043615 3 0.011
epiboly GO:0090504 8 0.011
response to temperature stimulus GO:0009266 55 0.011
response to steroid hormone GO:0048545 56 0.011
chorio allantoic fusion GO:0060710 8 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.011
response to estrogen GO:0043627 24 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
Mouse
alcohol metabolic process GO:0006066 116 0.011
regulation of lipase activity GO:0060191 15 0.011

Tnc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.327
musculoskeletal system disease DOID:17 0 0.327
connective tissue disease DOID:65 0 0.327
myopathy DOID:423 0 0.053
muscular disease DOID:0080000 0 0.053
muscle tissue disease DOID:66 0 0.053
collagen disease DOID:854 0 0.035
nervous system disease DOID:863 0 0.021
ehlers danlos syndrome DOID:13359 0 0.021
congenital muscular dystrophy DOID:0050557 0 0.015
muscular dystrophy DOID:9884 0 0.015
bone remodeling disease DOID:0080005 0 0.013
bone disease DOID:0080001 0 0.013
heart disease DOID:114 0 0.013
cardiovascular system disease DOID:1287 0 0.013
bone development disease DOID:0080006 0 0.012