|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
1.000
|
|
|
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
6 |
1.000
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
1.000
|
Human |
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
1.000
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
1.000
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
1.000
|
Rat |
|
|
necroptotic signaling pathway
|
GO:0097527 |
3 |
1.000
|
Mouse |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
1.000
|
Mouse |
|
|
defense response to other organism
|
GO:0098542 |
197 |
1.000
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
13 |
0.999
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.999
|
|
|
|
nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070427 |
5 |
0.999
|
|
|
|
response to interleukin 1
|
GO:0070555 |
11 |
0.999
|
|
|
|
cellular response to peptidoglycan
|
GO:0071224 |
4 |
0.999
|
|
|
|
nik nf kappab signaling
|
GO:0038061 |
14 |
0.999
|
|
|
|
negative regulation of interleukin 10 secretion
|
GO:2001180 |
2 |
0.999
|
|
|
|
regulation of cd8 positive alpha beta cytotoxic t cell extravasation
|
GO:2000452 |
2 |
0.998
|
|
|
|
regulation of antibacterial peptide biosynthetic process
|
GO:0002808 |
1 |
0.998
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
26 |
0.998
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.998
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.998
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.997
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.997
|
Mouse |
|
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.996
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.996
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.996
|
|
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.995
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.995
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.995
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.995
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.994
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.994
|
Rat |
|
|
negative regulation of interleukin 5 secretion
|
GO:2000663 |
1 |
0.993
|
|
|
|
cellular response to interleukin 18
|
GO:0071351 |
3 |
0.993
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.992
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.992
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.992
|
|
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
2 |
0.991
|
|
|
|
response to interleukin 15
|
GO:0070672 |
3 |
0.991
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.991
|
|
|
|
interleukin 5 secretion
|
GO:0072603 |
2 |
0.991
|
|
|
|
necroptotic process
|
GO:0070266 |
21 |
0.991
|
Mouse |
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.991
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.990
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.990
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.990
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.990
|
Human |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.989
|
Rat |
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.989
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.988
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.987
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.987
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.987
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.986
|
Rat |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.986
|
Rat |
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.986
|
Mouse |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.984
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.984
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.984
|
Human |
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.982
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.982
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.982
|
Mouse |
|
|
detection of molecule of bacterial origin
|
GO:0032490 |
2 |
0.981
|
|
|
|
ripoptosome assembly involved in necroptotic process
|
GO:1901026 |
6 |
0.980
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.980
|
Mouse |
|
|
i kappab phosphorylation
|
GO:0007252 |
6 |
0.980
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.978
|
|
|
|
interleukin 18 mediated signaling pathway
|
GO:0035655 |
2 |
0.978
|
|
|
|
interleukin 13 secretion
|
GO:0072611 |
2 |
0.977
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.976
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.976
|
|
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.976
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.975
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.971
|
Human |
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.969
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.967
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.967
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.966
|
|
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.964
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.964
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.963
|
Human |
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
21 |
0.963
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.962
|
|
|
|
induction by organism of immune response of other organism involved in symbiotic interaction
|
GO:0052558 |
1 |
0.962
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.959
|
Rat |
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.959
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.957
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.957
|
Mouse |
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.956
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.955
|
|
|
|
response to molecule of fungal origin
|
GO:0002238 |
4 |
0.954
|
|
|
|
negative regulation of odontogenesis of dentin containing tooth
|
GO:0042489 |
1 |
0.953
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.952
|
|
|
|
fever generation
|
GO:0001660 |
7 |
0.952
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.952
|
|
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.951
|
|
|
|
growth involved in symbiotic interaction
|
GO:0044110 |
23 |
0.943
|
|
|
|
positive regulation of cytokine secretion involved in immune response
|
GO:0002741 |
2 |
0.941
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.940
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.939
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.939
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.938
|
|
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.935
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.935
|
|
|
|
regulation of necroptotic process
|
GO:0060544 |
10 |
0.932
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.931
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.931
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.929
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.929
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.929
|
|
|
|
interleukin 6 biosynthetic process
|
GO:0042226 |
12 |
0.928
|
|
|
|
regulation of nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070428 |
3 |
0.927
|
|
|
|
activation of nf kappab inducing kinase activity
|
GO:0007250 |
4 |
0.926
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.925
|
Mouse |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.924
|
|
|
|
cellular response to lipoteichoic acid
|
GO:0071223 |
6 |
0.923
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.921
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.920
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.918
|
|
|
|
regulation of interleukin 5 secretion
|
GO:2000662 |
2 |
0.916
|
|
|
|
natural killer cell degranulation
|
GO:0043320 |
3 |
0.916
|
|
|
|
lymph node development
|
GO:0048535 |
18 |
0.914
|
|
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.913
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.911
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.911
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
17 |
0.911
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.911
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.908
|
Rat |
|
|
regulation of nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070424 |
3 |
0.907
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.906
|
|
|
|
negative regulation of reactive oxygen species biosynthetic process
|
GO:1903427 |
0 |
0.905
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.903
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.901
|
|
|
|
cellular response to interleukin 6
|
GO:0071354 |
9 |
0.901
|
|
|
|
positive regulation of cytokine production involved in immune response
|
GO:0002720 |
19 |
0.900
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.898
|
|
|
|
modulation of growth of symbiont involved in interaction with host
|
GO:0044144 |
19 |
0.896
|
|
|
|
peptide biosynthetic process
|
GO:0043043 |
11 |
0.894
|
|
|
|
negative regulation of interleukin 13 production
|
GO:0032696 |
2 |
0.894
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.893
|
Rat |
|
|
regulation of cytokine secretion involved in immune response
|
GO:0002739 |
4 |
0.893
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.893
|
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
9 |
0.893
|
|
|
|
regulation of interleukin 13 secretion
|
GO:2000665 |
2 |
0.890
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
30 |
0.885
|
|
|
|
regulation of antimicrobial peptide production
|
GO:0002784 |
1 |
0.885
|
|
|
|
spleen development
|
GO:0048536 |
39 |
0.879
|
Mouse |
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.878
|
|
|
|
negative regulation of interleukin 13 secretion
|
GO:2000666 |
1 |
0.875
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.875
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.870
|
|
|
|
activation induced cell death of t cells
|
GO:0006924 |
10 |
0.864
|
Mouse |
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.863
|
Mouse |
|
|
positive regulation of organic acid transport
|
GO:0032892 |
11 |
0.857
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.855
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.851
|
|
|
|
positive regulation of dna recombination
|
GO:0045911 |
17 |
0.850
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.846
|
|
|
|
response to peptidoglycan
|
GO:0032494 |
9 |
0.844
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.841
|
|
|
|
modulation by symbiont of defense related host nitric oxide production
|
GO:0052163 |
1 |
0.835
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.834
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.833
|
|
|
|
positive regulation by symbiont of defense related host nitric oxide production
|
GO:0052347 |
1 |
0.833
|
|
|
|
positive regulation of activation of membrane attack complex
|
GO:0001970 |
2 |
0.826
|
|
|
|
cytokine secretion involved in immune response
|
GO:0002374 |
6 |
0.824
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.824
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.821
|
Mouse |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.818
|
Human |
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.818
|
|
|
|
negative regulation of necroptotic process
|
GO:0060546 |
9 |
0.815
|
|
|
|
regulation of interleukin 6 biosynthetic process
|
GO:0045408 |
11 |
0.815
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.815
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.814
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.814
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.812
|
Rat |
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.811
|
|
|
|
regulation of interleukin 18 production
|
GO:0032661 |
3 |
0.809
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.809
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.808
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.806
|
Human |
|
|
response to defense related nitric oxide production by other organism involved in symbiotic interaction
|
GO:0052551 |
2 |
0.806
|
|
|
|
isotype switching to ige isotypes
|
GO:0048289 |
7 |
0.803
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.802
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.802
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.802
|
Rat |
|
|
chemokine production
|
GO:0032602 |
34 |
0.800
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.793
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.791
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.789
|
Rat |
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.788
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.786
|
Rat |
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.785
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.778
|
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.766
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.766
|
|
|
|
response to dsrna
|
GO:0043331 |
30 |
0.764
|
|
|
|
positive regulation of chronic inflammatory response
|
GO:0002678 |
4 |
0.762
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.757
|
Mouse |
|
|
acute phase response
|
GO:0006953 |
10 |
0.756
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.756
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.751
|
|
|
|
regulation of nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070432 |
3 |
0.750
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.748
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.747
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.742
|
|
|
|
positive regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031666 |
5 |
0.738
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.735
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.731
|
|
|
|
nucleotide binding domain leucine rich repeat containing receptor signaling pathway
|
GO:0035872 |
6 |
0.730
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.729
|
|
|
|
temperature homeostasis
|
GO:0001659 |
26 |
0.727
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.724
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.723
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.721
|
|
|
|
activation of membrane attack complex
|
GO:0001905 |
4 |
0.721
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
8 |
0.719
|
|
|
|
negative regulation of necrotic cell death
|
GO:0060547 |
11 |
0.715
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.713
|
Mouse |
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.708
|
|
|
|
positive regulation of fever generation
|
GO:0031622 |
6 |
0.707
|
|
|
|
negative regulation of growth of symbiont involved in interaction with host
|
GO:0044146 |
19 |
0.707
|
|
|
|
response to bacterial lipoprotein
|
GO:0032493 |
4 |
0.707
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.707
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.705
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.703
|
Mouse |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.703
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.702
|
|
|
|
negative regulation of odontogenesis
|
GO:0042483 |
3 |
0.700
|
|
|
|
regulation of activated t cell proliferation
|
GO:0046006 |
16 |
0.699
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.697
|
Mouse |
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
18 |
0.695
|
|
|
|
protein homooligomerization
|
GO:0051260 |
43 |
0.692
|
Mouse |
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.689
|
|
|
|
negative regulation of growth of symbiont in host
|
GO:0044130 |
19 |
0.689
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.687
|
Mouse |
|
|
positive regulation of fever generation by positive regulation of prostaglandin secretion
|
GO:0071812 |
2 |
0.684
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
25 |
0.678
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.675
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.675
|
Mouse |
|
|
positive regulation by symbiont of host immune response
|
GO:0052556 |
1 |
0.668
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.661
|
|
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.661
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.655
|
|
|
|
growth of symbiont involved in interaction with host
|
GO:0044116 |
23 |
0.652
|
|
|
|
regulation of fever generation
|
GO:0031620 |
6 |
0.652
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.652
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.647
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.644
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.643
|
|
|
|
negative regulation of ripoptosome assembly involved in necroptotic process
|
GO:1902443 |
3 |
0.635
|
|
|
|
response to lipoteichoic acid
|
GO:0070391 |
6 |
0.633
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.625
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.624
|
|
|
|
myd88 dependent toll like receptor signaling pathway
|
GO:0002755 |
7 |
0.622
|
|
|
|
positive regulation of protein activation cascade
|
GO:2000259 |
2 |
0.622
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.621
|
|
|
|
ripoptosome assembly
|
GO:0097343 |
6 |
0.619
|
|
|
|
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070430 |
1 |
0.608
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.606
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.603
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
14 |
0.599
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.596
|
|
|
|
negative regulation of interleukin 6 production
|
GO:0032715 |
17 |
0.593
|
Rat |
|
|
positive regulation of immature t cell proliferation
|
GO:0033091 |
4 |
0.593
|
|
|
|
type i interferon biosynthetic process
|
GO:0045351 |
9 |
0.592
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.591
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.590
|
|
|
|
regulation of macrophage fusion
|
GO:0034239 |
3 |
0.589
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.587
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.582
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.578
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.578
|
|
|
|
follicular dendritic cell differentiation
|
GO:0002268 |
2 |
0.569
|
|
|
|
b cell apoptotic process
|
GO:0001783 |
19 |
0.568
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.563
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.562
|
|
|
|
chemokine biosynthetic process
|
GO:0042033 |
8 |
0.560
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.555
|
Rat |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.551
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.551
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.549
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.548
|
|
|
|
positive regulation of interferon beta biosynthetic process
|
GO:0045359 |
3 |
0.545
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.543
|
Mouse |
|
|
negative regulation of glycolytic process
|
GO:0045820 |
4 |
0.538
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.535
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.534
|
|
|
|
interleukin 10 production
|
GO:0032613 |
23 |
0.533
|
|
|
|
regulation of necrotic cell death
|
GO:0010939 |
13 |
0.531
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.524
|
|
|
|
urea cycle
|
GO:0000050 |
2 |
0.521
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.518
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.516
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.515
|
Human |
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.514
|
|
|
|
marginal zone b cell differentiation
|
GO:0002315 |
2 |
0.513
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.510
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.507
|
Mouse |
|
|
gland development
|
GO:0048732 |
330 |
0.507
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.506
|
Human |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.505
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.502
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.502
|
Mouse |
|
|
macrophage cytokine production
|
GO:0010934 |
9 |
0.500
|
|
|
|
regulation of fever generation by regulation of prostaglandin secretion
|
GO:0071810 |
2 |
0.499
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.495
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.489
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.486
|
|
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
4 |
0.483
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.481
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.481
|
|
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.481
|
|
|
|
circadian temperature homeostasis
|
GO:0060086 |
2 |
0.475
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.475
|
Zebrafish |
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.473
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.471
|
Mouse Rat |
|
|
myelination
|
GO:0042552 |
74 |
0.469
|
|
|
|
cd8 positive alpha beta cytotoxic t cell extravasation
|
GO:0035698 |
2 |
0.464
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.461
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.461
|
Rat |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.460
|
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.456
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.450
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
44 |
0.449
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.446
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.446
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.446
|
Mouse |
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.436
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.435
|
Mouse |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.431
|
Mouse |
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.430
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.429
|
|
|
|
positive regulation of t cell migration
|
GO:2000406 |
10 |
0.428
|
|
|
|
oligodendrocyte apoptotic process
|
GO:0097252 |
1 |
0.428
|
|
|
|
mammary gland alveolus development
|
GO:0060749 |
22 |
0.428
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.427
|
|
|
|
negative regulation of tumor necrosis factor production
|
GO:0032720 |
17 |
0.426
|
|
|
|
positive regulation of interleukin 18 production
|
GO:0032741 |
2 |
0.425
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.424
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
21 |
0.423
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
15 |
0.423
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.419
|
Human |
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.419
|
|
|
|
regulation of chronic inflammatory response to antigenic stimulus
|
GO:0002874 |
3 |
0.415
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.414
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.412
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.411
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.407
|
|
|
|
interleukin 23 production
|
GO:0032627 |
2 |
0.406
|
|
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.405
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.404
|
|
|
|
induction by symbiont of host immune response
|
GO:0052559 |
1 |
0.403
|
|
|
|
interleukin 12 biosynthetic process
|
GO:0042090 |
8 |
0.400
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
22 |
0.400
|
|
|
|
response to defense related host nitric oxide production
|
GO:0052565 |
2 |
0.397
|
|
|
|
regulation of fatty acid transport
|
GO:2000191 |
10 |
0.397
|
|
|
|
interaction with host
|
GO:0051701 |
22 |
0.395
|
|
|
|
interleukin 1 mediated signaling pathway
|
GO:0070498 |
4 |
0.394
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.392
|
Mouse |
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.391
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.389
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.387
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.385
|
|
|
|
response to interleukin 18
|
GO:0070673 |
4 |
0.380
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.380
|
|
|
|
negative regulation of interferon gamma production
|
GO:0032689 |
18 |
0.379
|
|
|
|
modulation by organism of defense related nitric oxide production in other organism involved in symbiotic interaction
|
GO:0052302 |
1 |
0.377
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.376
|
|
|
|
negative regulation of interferon gamma mediated signaling pathway
|
GO:0060336 |
1 |
0.375
|
|
|
|
positive regulation of atp biosynthetic process
|
GO:2001171 |
2 |
0.374
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.374
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.369
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
2 |
0.367
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.365
|
|
|
|
regulation of anion transport
|
GO:0044070 |
27 |
0.363
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.362
|
|
|
|
positive regulation of type i interferon production
|
GO:0032481 |
14 |
0.361
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.361
|
Mouse |
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.359
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.355
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.354
|
|
|
|
cellular response to bacterial lipopeptide
|
GO:0071221 |
3 |
0.351
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.350
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.349
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.346
|
|
|
|
regulation of interleukin 23 production
|
GO:0032667 |
2 |
0.346
|
|
|
|
induction by organism of defense related nitric oxide production in other organism involved in symbiotic interaction
|
GO:0052263 |
1 |
0.344
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.344
|
|
|
|
type i interferon production
|
GO:0032606 |
29 |
0.343
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.343
|
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.341
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.340
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.338
|
Mouse |
|
|
modulation by symbiont of host immune response
|
GO:0052553 |
1 |
0.336
|
|
|
|
positive regulation of icosanoid secretion
|
GO:0032305 |
7 |
0.335
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.335
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.334
|
|
|
|
regulation of immunoglobulin secretion
|
GO:0051023 |
12 |
0.333
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.331
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.330
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.329
|
Mouse |
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.328
|
Mouse Rat |
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.325
|
|
|
|
positive regulation of activated t cell proliferation
|
GO:0042104 |
8 |
0.323
|
|
|
|
positive regulation of prostaglandin secretion
|
GO:0032308 |
5 |
0.323
|
|
|
|
inflammatory response to wounding
|
GO:0090594 |
4 |
0.322
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.322
|
|
|
|
positive regulation of chemokine biosynthetic process
|
GO:0045080 |
6 |
0.321
|
|
|
|
positive regulation of macrophage cytokine production
|
GO:0060907 |
7 |
0.320
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.320
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.319
|
Rat |
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.317
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.315
|
|
|
|
response to bacterial lipopeptide
|
GO:0070339 |
3 |
0.313
|
|
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.312
|
|
|
|
regulation of mast cell differentiation
|
GO:0060375 |
3 |
0.308
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.308
|
Mouse Rat |
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
23 |
0.305
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.305
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.304
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.304
|
Rat |
|
|
regulation of chronic inflammatory response
|
GO:0002676 |
7 |
0.304
|
|
|
|
regulation of natural killer cell proliferation
|
GO:0032817 |
2 |
0.303
|
|
|
|
regulation of antimicrobial peptide biosynthetic process
|
GO:0002805 |
1 |
0.301
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.299
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.296
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.296
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.292
|
|
|
|
positive regulation of apoptotic cell clearance
|
GO:2000427 |
3 |
0.291
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.287
|
Rat |
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.286
|
Mouse |
|
|
positive regulation of isotype switching to ige isotypes
|
GO:0048295 |
4 |
0.285
|
|
|
|
antibiotic transport
|
GO:0042891 |
1 |
0.284
|
|
|
|
positive regulation of cd4 positive alpha beta t cell activation
|
GO:2000516 |
16 |
0.281
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.280
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.279
|
|
|
|
cellular response to bacterial lipoprotein
|
GO:0071220 |
3 |
0.279
|
|
|
|
chronic inflammatory response
|
GO:0002544 |
9 |
0.278
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.274
|
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
6 |
0.274
|
|
|
|
activation of jnkk activity
|
GO:0007256 |
3 |
0.273
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.272
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.272
|
|
|
|
regulation of chemokine secretion
|
GO:0090196 |
4 |
0.271
|
|
|
|
regulation of mhc class ii biosynthetic process
|
GO:0045346 |
7 |
0.269
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.268
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.267
|
|
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.267
|
|
|
|
positive regulation of response to biotic stimulus
|
GO:0002833 |
15 |
0.266
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.262
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
28 |
0.262
|
|
|
|
positive regulation of fatty acid transport
|
GO:2000193 |
8 |
0.261
|
|
|
|
fatty acid derivative transport
|
GO:1901571 |
14 |
0.260
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.258
|
|
|
|
heat generation
|
GO:0031649 |
13 |
0.258
|
|
|
|
positive regulation of interleukin 12 biosynthetic process
|
GO:0045084 |
6 |
0.258
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.257
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.257
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.257
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.254
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.248
|
|
|
|
regulation of nik nf kappab signaling
|
GO:1901222 |
10 |
0.247
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.245
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.245
|
|
|
|
response to host immune response
|
GO:0052572 |
3 |
0.245
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.243
|
Rat |
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.243
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.241
|
|
|
|
wound healing involved in inflammatory response
|
GO:0002246 |
4 |
0.238
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.237
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.236
|
|
|
|
response to exogenous dsrna
|
GO:0043330 |
22 |
0.236
|
|
|
|
follicular dendritic cell activation
|
GO:0002266 |
2 |
0.234
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.231
|
|
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
4 |
0.231
|
|
|
|
positive regulation of macrophage activation
|
GO:0043032 |
10 |
0.230
|
|
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.229
|
|
|
|
mammary gland epithelial cell proliferation
|
GO:0033598 |
24 |
0.228
|
|
|
|
negative regulation of chronic inflammatory response
|
GO:0002677 |
3 |
0.228
|
|
|
|
regulation of oligodendrocyte differentiation
|
GO:0048713 |
23 |
0.228
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.228
|
Rat |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.226
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.224
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.220
|
|
|
|
regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031664 |
9 |
0.219
|
|
|
|
positive regulation of lipid transport
|
GO:0032370 |
22 |
0.217
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.217
|
|
