|
|
interleukin 18 mediated signaling pathway
|
GO:0035655 |
2 |
0.998
|
|
|
|
cellular response to interleukin 18
|
GO:0071351 |
3 |
0.989
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.989
|
|
|
|
cellular response to peptidoglycan
|
GO:0071224 |
4 |
0.980
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.979
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.974
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.969
|
Human Mouse |
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.968
|
Mouse |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.966
|
Mouse |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.961
|
Mouse |
|
|
immune effector process
|
GO:0002252 |
321 |
0.957
|
Mouse |
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.956
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.951
|
|
|
|
detection of molecule of bacterial origin
|
GO:0032490 |
2 |
0.946
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.940
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.938
|
Mouse |
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.937
|
Mouse |
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.936
|
|
|
|
modulation of growth of symbiont involved in interaction with host
|
GO:0044144 |
19 |
0.932
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.926
|
Mouse |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.922
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.921
|
Mouse |
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.917
|
Human Mouse |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.912
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.906
|
Human |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.901
|
Human |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.899
|
Human |
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.898
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.890
|
|
|
|
chemokine biosynthetic process
|
GO:0042033 |
8 |
0.885
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.880
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.878
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.877
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
0.875
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.867
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.844
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.836
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.831
|
|
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.824
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.822
|
Mouse |
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.818
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.815
|
Mouse |
|
|
positive regulation of fever generation
|
GO:0031622 |
6 |
0.808
|
Mouse |
|
|
cytokine production
|
GO:0001816 |
319 |
0.800
|
Mouse |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.789
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.789
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.788
|
|
|
|
apoptotic cell clearance
|
GO:0043277 |
17 |
0.785
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.782
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.779
|
Mouse |
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.776
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.776
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.775
|
Mouse |
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.770
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.765
|
Mouse |
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.754
|
|
|
|
fever generation
|
GO:0001660 |
7 |
0.739
|
Mouse |
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.733
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.725
|
Mouse |
|
|
positive regulation of interleukin 18 production
|
GO:0032741 |
2 |
0.724
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.722
|
|
|
|
positive regulation by symbiont of defense related host nitric oxide production
|
GO:0052347 |
1 |
0.709
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.708
|
|
|
|
necroptotic signaling pathway
|
GO:0097527 |
3 |
0.707
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.702
|
Mouse |
|
|
negative regulation of growth of symbiont involved in interaction with host
|
GO:0044146 |
19 |
0.689
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.686
|
Mouse |
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.682
|
|
|
|
t helper 17 cell lineage commitment
|
GO:0072540 |
4 |
0.680
|
|
|
|
chemokine production
|
GO:0032602 |
34 |
0.680
|
|
|
|
induction by organism of immune response of other organism involved in symbiotic interaction
|
GO:0052558 |
1 |
0.677
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.676
|
Mouse |
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.668
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.667
|
Mouse |
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.665
|
Mouse |
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.663
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.663
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.655
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.655
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.654
|
Mouse |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.648
|
Mouse |
|
|
regulation of vascular endothelial growth factor production
|
GO:0010574 |
13 |
0.642
|
|
|
|
regulation of chronic inflammatory response to antigenic stimulus
|
GO:0002874 |
3 |
0.633
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.621
|
Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.621
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.613
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.602
|
|
|
|
positive regulation of fatty acid transport
|
GO:2000193 |
8 |
0.601
|
Mouse |
|
|
response to interleukin 1
|
GO:0070555 |
11 |
0.600
|
Mouse |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.594
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.590
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.583
|
Mouse |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.581
|
Human |
|
|
acute phase response
|
GO:0006953 |
10 |
0.580
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.577
|
|
|
|
interleukin 6 biosynthetic process
|
GO:0042226 |
12 |
0.576
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.576
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.574
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.572
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.572
|
|
|
|
heat generation
|
GO:0031649 |
13 |
0.566
|
Mouse |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.563
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.557
|
Mouse |
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.553
|
|
|
|
response to bacterial lipoprotein
|
GO:0032493 |
4 |
0.549
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.548
|
|
|
|
necroptotic process
|
GO:0070266 |
21 |
0.544
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.541
|
|
|
|
growth of symbiont involved in interaction with host
|
GO:0044116 |
23 |
0.540
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.537
|
Mouse |
|
|
regulation of heat generation
|
GO:0031650 |
8 |
0.523
|
Mouse |
|
|
vascular endothelial growth factor production
|
GO:0010573 |
13 |
0.522
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.521
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
8 |
0.519
|
|
|
|
regulation of interleukin 6 biosynthetic process
|
GO:0045408 |
11 |
0.514
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.514
|
|
|
|
growth involved in symbiotic interaction
|
GO:0044110 |
23 |
0.504
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.502
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.500
|
|
|
|
regulation of nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070424 |
3 |
0.491
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.488
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.486
|
Mouse |
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.484
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.479
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.479
|
Mouse |
|
|
negative regulation of chemokine production
|
GO:0032682 |
4 |
0.476
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.474
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.472
|
Mouse |
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.468
|
|
|
|
inflammatory response to wounding
|
GO:0090594 |
4 |
0.467
|
|
|
|
negative regulation of growth of symbiont in host
|
GO:0044130 |
19 |
0.458
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.457
|
|
|
|
chemokine metabolic process
|
GO:0050755 |
10 |
0.456
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.455
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
26 |
0.455
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.450
|
|
|
|
modulation by symbiont of defense related host nitric oxide production
|
GO:0052163 |
1 |
0.445
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.445
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.442
|
Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.441
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.441
|
Mouse |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.438
|
Mouse |
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.432
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.425
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.421
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.416
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.416
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.415
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.413
|
Mouse |
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.412
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.411
|
Mouse |
|
|
regulation of chemokine biosynthetic process
|
GO:0045073 |
8 |
0.409
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.407
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.407
|
Mouse |
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.403
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.403
|
|
|
|
translation
|
GO:0006412 |
93 |
0.401
|
|
|
|
positive regulation of apoptotic cell clearance
|
GO:2000427 |
3 |
0.401
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.400
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.397
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.386
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
25 |
0.386
|
|
|
|
interleukin 33 mediated signaling pathway
|
GO:0038172 |
1 |
0.384
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.381
|
Mouse |
|
|
positive regulation of type i interferon production
|
GO:0032481 |
14 |
0.381
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.379
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.373
|
Mouse |
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.373
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.371
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.360
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.360
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.359
|
Mouse |
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.358
|
|
|
|
response to defense related nitric oxide production by other organism involved in symbiotic interaction
|
GO:0052551 |
2 |
0.356
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.353
|
Mouse |
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.346
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.346
|
|
|
|
chronic inflammatory response to antigenic stimulus
|
GO:0002439 |
3 |
0.344
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.342
|
|
|
|
positive regulation of chronic inflammatory response
|
GO:0002678 |
4 |
0.339
|
|
|
|
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070430 |
1 |
0.336
|
|
|
|
i kappab phosphorylation
|
GO:0007252 |
6 |
0.328
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.327
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.326
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.326
|
Mouse |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.325
|
Mouse |
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.324
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.323
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.323
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.320
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.319
|
Mouse |
|
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
6 |
0.319
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.319
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.319
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.318
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.318
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.317
|
Mouse |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.314
|
Mouse |
|
|
anion transport
|
GO:0006820 |
177 |
0.313
|
Mouse |
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
13 |
0.312
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.309
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.308
|
Mouse |
|
|
b cell activation
|
GO:0042113 |
161 |
0.308
|
Mouse |
|
|
phagocytosis
|
GO:0006909 |
66 |
0.307
|
|
|
|
regulation of nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070428 |
3 |
0.306
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.305
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.305
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.304
|
Mouse |
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.303
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.303
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.301
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.301
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.299
|
Mouse |
|
|
organic acid transport
|
GO:0015849 |
101 |
0.298
|
Mouse |
|
|
response to interleukin 18
|
GO:0070673 |
4 |
0.297
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.292
|
Mouse |
|
|
t helper 17 cell differentiation
|
GO:0072539 |
7 |
0.289
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.288
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.286
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.283
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.281
|
Mouse |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.280
|
Mouse |
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.280
|
Mouse |
|
|
branching involved in salivary gland morphogenesis
|
GO:0060445 |
26 |
0.280
|
|
|
|
positive regulation of organic acid transport
|
GO:0032892 |
11 |
0.279
|
Mouse |
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.279
|
Mouse |
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.279
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.278
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.277
|
Mouse |
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.275
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.274
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.274
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.272
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.269
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.269
|
Mouse |
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.269
|
Mouse |
|
|
humoral immune response
|
GO:0006959 |
57 |
0.265
|
Mouse |
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.262
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.261
|
Mouse |
|
|
protein complex localization
|
GO:0031503 |
19 |
0.258
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.257
|
|
|
|
superoxide metabolic process
|
GO:0006801 |
27 |
0.256
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.253
|
Mouse |
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.252
|
|
|
|
positive regulation by symbiont of host immune response
|
GO:0052556 |
1 |
0.251
|
|
|
|
negative regulation of interleukin 10 secretion
|
GO:2001180 |
2 |
0.250
|
Mouse |
|
|
positive regulation of interferon beta biosynthetic process
|
GO:0045359 |
3 |
0.247
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.243
|
Mouse |
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.243
|
|
|
|
negative regulation of myeloid dendritic cell activation
|
GO:0030886 |
3 |
0.242
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
0.242
|
|
|
|
regulation of anion transport
|
GO:0044070 |
27 |
0.241
|
Mouse |
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.239
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.238
|
Mouse |
|
|
peptide transport
|
GO:0015833 |
133 |
0.237
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.237
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.232
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.232
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.231
|
|
|
|
salivary gland development
|
GO:0007431 |
37 |
0.231
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.229
|
|
|
|
negative regulation of reactive oxygen species biosynthetic process
|
GO:1903427 |
0 |
0.229
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.228
|
|
|
|
mammary gland epithelial cell proliferation
|
GO:0033598 |
24 |
0.226
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.225
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.223
|
Mouse |
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
32 |
0.223
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.220
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.219
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.219
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.219
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.218
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.216
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.215
|
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.214
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.210
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.206
|
Mouse |
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.206
|
Mouse |
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.206
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.205
|
|
|
|
regulation of chemokine secretion
|
GO:0090196 |
4 |
0.205
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.204
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.204
|
Mouse |
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.204
|
Mouse |
|
|
macrophage activation
|
GO:0042116 |
27 |
0.204
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.203
|
Mouse |
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.202
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.199
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.198
|
Mouse |
|
|
transcription factor import into nucleus
|
GO:0042991 |
26 |
0.198
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.197
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.196
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.195
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.195
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.195
|
|
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.194
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.193
|
Mouse |
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.192
|
Mouse |
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.190
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.189
|
Mouse |
|
|
positive regulation of icosanoid secretion
|
GO:0032305 |
7 |
0.186
|
Mouse |
|
|
leukocyte aggregation
|
GO:0070486 |
1 |
0.183
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.182
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.182
|
|
|
|
myd88 dependent toll like receptor signaling pathway
|
GO:0002755 |
7 |
0.180
|
|
|
|
positive regulation of translational initiation
|
GO:0045948 |
4 |
0.179
|
|
|
|
response to host immune response
|
GO:0052572 |
3 |
0.178
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.178
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
5 |
0.177
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.176
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.175
|
Mouse |
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.175
|
Mouse |
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.174
|
Mouse |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.173
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.173
|
Mouse |
|
|
response to amino acid
|
GO:0043200 |
37 |
0.172
|
|
|
|
regulation of fever generation
|
GO:0031620 |
6 |
0.172
|
Mouse |
|
|
protein secretion
|
GO:0009306 |
111 |
0.172
|
Mouse |
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.171
|
|
|
|
positive regulation of type 2 immune response
|
GO:0002830 |
9 |
0.169
|
|
|
|
response to defense related host nitric oxide production
|
GO:0052565 |
2 |
0.168
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.168
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.167
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
17 |
0.167
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.166
|
Mouse |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.166
|
Mouse |
|
|
protein targeting
|
GO:0006605 |
143 |
0.166
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.164
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.164
|
|
|
|
wound healing involved in inflammatory response
|
GO:0002246 |
4 |
0.163
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.163
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.162
|
Mouse |
|
|
membrane invagination
|
GO:0010324 |
17 |
0.159
|
|
|
|
neutrophil apoptotic process
|
GO:0001781 |
3 |
0.159
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.159
|
Mouse |
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.158
|
|
|
|
regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031664 |
9 |
0.158
|
|
|
|
induction by organism of defense related nitric oxide production in other organism involved in symbiotic interaction
|
GO:0052263 |
1 |
0.156
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.156
|
Human |
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.156
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.156
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.155
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.155
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.155
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.152
|
Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.152
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.152
|
|
|
|
modulation by symbiont of host immune response
|
GO:0052553 |
1 |
0.152
|
|
|
|
response to peptidoglycan
|
GO:0032494 |
9 |
0.152
|
|
|
|
cellular response to bacterial lipoprotein
|
GO:0071220 |
3 |
0.152
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.151
|
Mouse |
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.150
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.149
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.148
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.146
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.146
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.146
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.145
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.145
|
|
|
|
chronic inflammatory response
|
GO:0002544 |
9 |
0.144
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.143
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.143
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.142
|
|
|
|
regulation of fatty acid transport
|
GO:2000191 |
10 |
0.142
|
Mouse |
|
|
negative regulation of t helper 1 type immune response
|
GO:0002826 |
5 |
0.141
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.141
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.140
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.139
|
|
|
|
induction by symbiont of host immune response
|
GO:0052559 |
1 |
0.139
|
|
|
|
chemokine secretion
|
GO:0090195 |
5 |
0.139
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.138
|
Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.137
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.137
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
3 |
0.136
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.135
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.134
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.133
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.133
|
Mouse |
|
|
positive regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031666 |
5 |
0.133
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
44 |
0.132
|
Mouse |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.132
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.132
|
Mouse |
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.130
|
|
|
|
secondary metabolic process
|
GO:0019748 |
18 |
0.129
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.128
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.127
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.126
|
Mouse |
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.126
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.125
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.124
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.123
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.123
|
Mouse |
|
|
positive regulation of brown fat cell differentiation
|
GO:0090336 |
4 |
0.122
|
|
|
|
response to host defenses
|
GO:0052200 |
3 |
0.121
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.120
|
|
|
|
negative regulation of cytokine biosynthetic process
|
GO:0042036 |
13 |
0.118
|
|
|
|
negative regulation of multicellular organismal metabolic process
|
GO:0044252 |
1 |
0.116
|
|
|
|
antibiotic transport
|
GO:0042891 |
1 |
0.115
|
|
|
|
regulation of nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070432 |
3 |
0.115
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.115
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.115
|
Mouse |
|
|
activation of jun kinase activity
|
GO:0007257 |
15 |
0.114
|
|
|
|
response to defenses of other organism involved in symbiotic interaction
|
GO:0052173 |
3 |
0.114
|
|
|
|
response to dsrna
|
GO:0043331 |
30 |
0.114
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.114
|
|
|
|
interleukin 6 mediated signaling pathway
|
GO:0070102 |
6 |
0.114
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.114
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.113
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
23 |
0.113
|
|
|
|
regulation of chronic inflammatory response
|
GO:0002676 |
7 |
0.113
|
|
|
|
icosanoid transport
|
GO:0071715 |
14 |
0.113
|
Mouse |
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.113
|
Mouse |
|
|
interleukin 11 mediated signaling pathway
|
GO:0038154 |
2 |
0.112
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.112
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.112
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
17 |
0.111
|
Mouse |
|
|
positive regulation of fever generation by positive regulation of prostaglandin secretion
|
GO:0071812 |
2 |
0.109
|
Mouse |
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.109
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.109
|
|
|
|
positive regulation by organism of defense response of other organism involved in symbiotic interaction
|
GO:0052510 |
1 |
0.109
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.109
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.108
|
Mouse |
|
|
positive regulation of heat generation
|
GO:0031652 |
7 |
0.107
|
Mouse |
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.107
|
Mouse |
|
|
corticotropin releasing hormone secretion
|
GO:0043396 |
2 |
0.107
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.107
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.107
|
Mouse |
|
|
muscle cell development
|
GO:0055001 |
133 |
0.107
|
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
6 |
0.106
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.104
|
|
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
4 |
0.103
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.103
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.103
|
Mouse |
|
|
response to fructose
|
GO:0009750 |
2 |
0.103
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.102
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.102
|
|
|
|
keratinocyte migration
|
GO:0051546 |
3 |
0.101
|
|
|
|
negative regulation of chemokine biosynthetic process
|
GO:0045079 |
2 |
0.101
|
|
|
|
positive regulation of syncytium formation by plasma membrane fusion
|
GO:0060143 |
17 |
0.101
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.101
|
Mouse |
|
|
positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070434 |
2 |
0.100
|
|
|
|
regulation of lipid transport
|
GO:0032368 |
36 |
0.100
|
Mouse |
|
|
positive regulation of myoblast differentiation
|
GO:0045663 |
8 |
0.100
|
|
|
|
regulation of corticotropin releasing hormone secretion
|
GO:0043397 |
2 |
0.100
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.100
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.099
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.099
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.097
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.097
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.097
|
|
|
|
type i interferon biosynthetic process
|
GO:0045351 |
9 |
0.097
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.096
|
Mouse |
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.096
|
Mouse |
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.096
|
|
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.096
|
|
|
|
antibacterial peptide secretion
|
GO:0002779 |
1 |
0.096
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
11 |
0.096
|
Mouse |
|
|
negative regulation of interleukin 6 production
|
GO:0032715 |
17 |
0.095
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.094
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.094
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.094
|
Human |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.092
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.092
|
Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.092
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.091
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.091
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
25 |
0.090
|
|
|
|
positive regulation of lipid transport
|
GO:0032370 |
22 |
0.090
|
Mouse |
|
|
response to protozoan
|
GO:0001562 |
28 |
0.090
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.089
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.089
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.089
|
|
|
|
modulation by organism of defense response of other organism involved in symbiotic interaction
|
GO:0052255 |
1 |
0.088
|
|
|
|
positive regulation of chronic inflammatory response to antigenic stimulus
|
GO:0002876 |
2 |
0.088
|
|
|
|
positive regulation of macrophage activation
|
GO:0043032 |
10 |
0.088
|
|
|
|
nitric oxide production involved in inflammatory response
|
GO:0002537 |
2 |
0.087
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.087
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.087
|
Mouse |
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
30 |
0.086
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.086
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.086
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.085
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.085
|
Mouse |
|
|
pigment metabolic process
|
GO:0042440 |
32 |
0.085
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.085
|
|
|
|
negative regulation of glucose transport
|
GO:0010829 |
9 |
0.085
|
|
|
|
lymphocyte chemotaxis
|
GO:0048247 |
10 |
0.084
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.084
|
|
|
|
positive regulation of t cell migration
|
GO:2000406 |
10 |
0.084
|
Mouse |
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.084
|
Mouse |
|
|
nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070427 |
5 |
0.084
|
|
