Mus musculus

0 known processes

Tnfsf10

tumor necrosis factor (ligand) superfamily, member 10

(Aliases: TL2,A330042I21Rik,Trail,APO-2L,Ly81,AI448571)

Tnfsf10 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cytokine production GO:0001816 319 0.712
Mouse
innate immune response GO:0045087 157 0.707
Fly
response to molecule of bacterial origin GO:0002237 143 0.668
Mouse
regulation of defense response GO:0031347 233 0.666
Mouse
interspecies interaction between organisms GO:0044419 83 0.596
Mouse
immune effector process GO:0002252 321 0.421
Mouse
regulation of cytokine production GO:0001817 266 0.411
Mouse
myeloid cell differentiation GO:0030099 233 0.400
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.398
pattern recognition receptor signaling pathway GO:0002221 47 0.388
cellular response to interferon beta GO:0035458 21 0.385
immune response activating signal transduction GO:0002757 116 0.359
activation of immune response GO:0002253 138 0.349
lymphocyte differentiation GO:0030098 242 0.340
Mouse
cellular response to lipid GO:0071396 145 0.339
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.337
Mouse
response to lipopolysaccharide GO:0032496 128 0.326
Mouse
regulation of innate immune response GO:0045088 91 0.314
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.309
leukocyte proliferation GO:0070661 172 0.308
Mouse
positive regulation of cytokine production GO:0001819 174 0.304
Mouse
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.304
negative regulation of protein metabolic process GO:0051248 282 0.296
adaptive immune response GO:0002250 155 0.283
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.268
Mouse
positive regulation of defense response GO:0031349 124 0.251
Mouse
defense response to virus GO:0051607 68 0.245
immune response regulating signaling pathway GO:0002764 125 0.240
activation of innate immune response GO:0002218 56 0.224
negative regulation of molecular function GO:0044092 258 0.211
Mouse
defense response to bacterium GO:0042742 119 0.208
Mouse Fly
regulation of leukocyte proliferation GO:0070663 121 0.201
myeloid leukocyte differentiation GO:0002573 119 0.199
Mouse
defense response to other organism GO:0098542 197 0.188
Mouse Fly
leukocyte differentiation GO:0002521 342 0.187
Mouse
positive regulation of innate immune response GO:0045089 80 0.182
t cell differentiation GO:0030217 174 0.180
protein catabolic process GO:0030163 221 0.178
i kappab kinase nf kappab signaling GO:0007249 85 0.178
Human Mouse
negative regulation of immune system process GO:0002683 209 0.175
t cell activation GO:0042110 289 0.174
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.166
negative regulation of cell proliferation GO:0008285 296 0.163
innate immune response activating signal transduction GO:0002758 50 0.161
viral process GO:0016032 41 0.158
cellular response to molecule of bacterial origin GO:0071219 83 0.157
Mouse
interferon gamma production GO:0032609 67 0.156
Mouse
tumor necrosis factor production GO:0032640 50 0.154
regulation of lymphocyte activation GO:0051249 240 0.152
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.152
protein ubiquitination GO:0016567 171 0.151
cytokine mediated signaling pathway GO:0019221 115 0.149
Mouse
protein modification by small protein conjugation GO:0032446 187 0.148
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.140
Human
positive regulation of t cell activation GO:0050870 101 0.138
Mouse
negative regulation of protein modification process GO:0031400 163 0.137
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.130
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.128
regulation of establishment of protein localization GO:0070201 181 0.126
Mouse
regulation of defense response to virus GO:0050688 18 0.125
reactive oxygen species metabolic process GO:0072593 84 0.124
Mouse
negative regulation of phosphorylation GO:0042326 166 0.123
cell activation involved in immune response GO:0002263 126 0.119
Mouse
positive regulation of viral entry into host cell GO:0046598 3 0.119
cytokine secretion GO:0050663 72 0.119
inflammatory response GO:0006954 244 0.115
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.112
Human Mouse Fly
regulation of protein localization GO:0032880 231 0.112
Mouse
negative regulation of cytokine production GO:0001818 84 0.110
negative regulation of phosphate metabolic process GO:0045936 184 0.109
Mouse
lymphocyte proliferation GO:0046651 164 0.107
regulation of response to wounding GO:1903034 189 0.107
Mouse
angiogenesis GO:0001525 201 0.107
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.106
Mouse
regulation of cell activation GO:0050865 289 0.105
Mouse
blood vessel morphogenesis GO:0048514 285 0.105
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.101
positive regulation of lymphocyte activation GO:0051251 140 0.101
Mouse
mapk cascade GO:0000165 281 0.101
Mouse Fly
apoptotic signaling pathway GO:0097190 306 0.101
Human Mouse Fly
positive regulation of viral genome replication GO:0045070 2 0.100
negative regulation of necroptotic process GO:0060546 9 0.098
response to interferon gamma GO:0034341 34 0.096
nucleoside phosphate metabolic process GO:0006753 338 0.093
negative regulation of viral transcription GO:0032897 3 0.093
regulation of cytokine secretion GO:0050707 61 0.092
alpha beta t cell activation GO:0046631 91 0.090
cellular macromolecule catabolic process GO:0044265 206 0.090
regulation of t cell activation GO:0050863 170 0.090
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.090
Mouse
cell type specific apoptotic process GO:0097285 268 0.088
viral gene expression GO:0019080 3 0.084
b cell proliferation GO:0042100 53 0.084
intracellular protein transport GO:0006886 204 0.084
Mouse
regulation of defense response to bacterium GO:1900424 3 0.080
macromolecule catabolic process GO:0009057 281 0.080
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.080
divalent inorganic cation transport GO:0072511 178 0.080
positive regulation of secretion GO:0051047 130 0.080
Mouse
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.079
protein oligomerization GO:0051259 67 0.078
Mouse
negative regulation of multi organism process GO:0043901 68 0.078
Mouse
leukocyte mediated cytotoxicity GO:0001909 62 0.077
leukocyte apoptotic process GO:0071887 71 0.077
negative regulation of defense response GO:0031348 77 0.077
carbohydrate derivative biosynthetic process GO:1901137 183 0.077
regulation of angiogenesis GO:0045765 81 0.077
ribonucleoside triphosphate metabolic process GO:0009199 220 0.077
nucleotide metabolic process GO:0009117 332 0.076
defense response to gram positive bacterium GO:0050830 50 0.075
Mouse
regulation of multi organism process GO:0043900 111 0.074
Mouse
engulfment of apoptotic cell GO:0043652 3 0.073
Fly
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.072
Mouse
cell killing GO:0001906 67 0.072
positive regulation of interleukin 1 alpha production GO:0032730 4 0.072
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.072
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.071
regulation of toll like receptor signaling pathway GO:0034121 20 0.071
regulation of ion homeostasis GO:2000021 64 0.071
forebrain development GO:0030900 302 0.071
toll like receptor signaling pathway GO:0002224 38 0.070
regulation of protein catabolic process GO:0042176 108 0.070
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.069
nucleobase containing small molecule metabolic process GO:0055086 352 0.069
interleukin 1 beta secretion GO:0050702 16 0.068
positive regulation of cell activation GO:0050867 158 0.067
Mouse
mitochondrion organization GO:0007005 134 0.067
Human
regulation of lymphocyte mediated immunity GO:0002706 84 0.067
Mouse
epithelial tube morphogenesis GO:0060562 303 0.067
organic cyclic compound catabolic process GO:1901361 295 0.067
protein localization to nucleus GO:0034504 121 0.066
Mouse
sequestering of metal ion GO:0051238 19 0.066
aromatic compound catabolic process GO:0019439 286 0.066
protein maturation GO:0051604 176 0.066
Mouse
sequestering of calcium ion GO:0051208 18 0.065
regulation of peptidase activity GO:0052547 96 0.065
Human Mouse
cation transport GO:0006812 399 0.064
blood circulation GO:0008015 195 0.064
protein import into nucleus GO:0006606 95 0.064
Mouse
protein processing GO:0016485 163 0.064
Mouse
t cell proliferation GO:0042098 120 0.062
regulation of cell cycle GO:0051726 281 0.062
mature dendritic cell differentiation GO:0097029 3 0.061
regulation of response to biotic stimulus GO:0002831 38 0.059
regulation of mapk cascade GO:0043408 248 0.059
Mouse
divalent metal ion transport GO:0070838 172 0.059
establishment of protein localization to organelle GO:0072594 118 0.058
Mouse
organophosphate catabolic process GO:0046434 232 0.058
regulation of t cell proliferation GO:0042129 92 0.058
cellular protein complex assembly GO:0043623 116 0.058
cellular amine metabolic process GO:0044106 44 0.057
positive regulation of lymphocyte proliferation GO:0050671 70 0.057
carboxylic acid transport GO:0046942 100 0.056
Mouse
signal transduction in absence of ligand GO:0038034 55 0.056
response to organonitrogen compound GO:0010243 246 0.055
Mouse
anion transport GO:0006820 177 0.055
Mouse
nitrogen compound transport GO:0071705 271 0.055
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.054
Human
viral transcription GO:0019083 3 0.054
positive regulation of immune effector process GO:0002699 107 0.054
Mouse
t cell mediated cytotoxicity GO:0001913 26 0.054
regulation of interferon gamma production GO:0032649 57 0.053
Mouse
interleukin 1 alpha secretion GO:0050703 3 0.053
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.053
negative regulation of angiogenesis GO:0016525 25 0.053
ribose phosphate metabolic process GO:0019693 291 0.053
regulation of cysteine type endopeptidase activity GO:2000116 65 0.053
Human Mouse
sensory perception GO:0007600 245 0.053
glycosyl compound metabolic process GO:1901657 246 0.053
cytoplasmic transport GO:0016482 234 0.052
Mouse
t cell mediated immunity GO:0002456 50 0.052
regulation of protein transport GO:0051223 163 0.052
Mouse
regulation of interleukin 1 production GO:0032652 26 0.052
antigen receptor mediated signaling pathway GO:0050851 64 0.051
regulation of defense response to virus by host GO:0050691 8 0.051
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.051
cellular response to interferon alpha GO:0035457 4 0.051
regulation of interleukin 1 beta secretion GO:0050706 15 0.051
negative regulation of intracellular signal transduction GO:1902532 167 0.051
circulatory system process GO:0003013 197 0.051
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.051
reactive oxygen species biosynthetic process GO:1903409 8 0.050
ribonucleoside catabolic process GO:0042454 206 0.050
natural killer cell activation GO:0030101 44 0.050
stress activated mapk cascade GO:0051403 80 0.050
Mouse Fly
regulation of b cell proliferation GO:0030888 39 0.049
positive regulation of endopeptidase activity GO:0010950 43 0.049
Human Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.049
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.048
regulation of interleukin 1 alpha production GO:0032650 4 0.048
regulation of hormone levels GO:0010817 211 0.048
Mouse
regulation of cell motility GO:2000145 236 0.048
Mouse
regulation of hydrolase activity GO:0051336 246 0.047
Human Mouse
modification dependent protein catabolic process GO:0019941 133 0.047
cellular response to dna damage stimulus GO:0006974 207 0.047
Mouse
negative regulation of macrophage apoptotic process GO:2000110 3 0.047
purine nucleoside triphosphate catabolic process GO:0009146 203 0.047
regulation of cell killing GO:0031341 40 0.047
nucleocytoplasmic transport GO:0006913 139 0.047
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.047
cellular protein catabolic process GO:0044257 155 0.047
divalent inorganic cation homeostasis GO:0072507 138 0.046
Mouse
ubiquitin dependent protein catabolic process GO:0006511 129 0.046
positive regulation of leukocyte proliferation GO:0070665 73 0.046
calcium ion transport GO:0006816 159 0.045
t cell receptor signaling pathway GO:0050852 46 0.045
membrane organization GO:0061024 245 0.045
Fly
transmembrane transport GO:0055085 412 0.045
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.045
homeostasis of number of cells GO:0048872 210 0.045
nuclear transport GO:0051169 139 0.045
Mouse
modification dependent macromolecule catabolic process GO:0043632 133 0.044
alpha beta t cell differentiation GO:0046632 69 0.044
regulation of cell migration GO:0030334 219 0.044
Mouse
regulation of leukocyte apoptotic process GO:2000106 56 0.044
response to organic cyclic compound GO:0014070 198 0.044
ribonucleotide metabolic process GO:0009259 291 0.044
entry into other organism involved in symbiotic interaction GO:0051828 15 0.044
viral life cycle GO:0019058 36 0.044
eosinophil activation involved in immune response GO:0002278 1 0.043
nucleoside phosphate catabolic process GO:1901292 222 0.043
defense response to protozoan GO:0042832 25 0.043
cellular nitrogen compound catabolic process GO:0044270 280 0.043
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.043
regulation of vasculature development GO:1901342 88 0.043
interleukin 1 production GO:0032612 31 0.043
positive regulation of protein transport GO:0051222 93 0.042
Mouse
metal ion homeostasis GO:0055065 189 0.042
Mouse
cellular response to molecule of fungal origin GO:0071226 2 0.042
organic acid transport GO:0015849 101 0.042
Mouse
cation homeostasis GO:0055080 212 0.041
Mouse
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.041
Human Mouse
cellular response to biotic stimulus GO:0071216 92 0.041
Mouse
regulation of interleukin 1 secretion GO:0050704 15 0.041
cytokine biosynthetic process GO:0042089 68 0.041
regulation of monocyte chemotaxis GO:0090025 3 0.041
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.041
Human Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.040
negative regulation of homeostatic process GO:0032845 71 0.040
glial cell apoptotic process GO:0034349 3 0.040
natural killer cell mediated cytotoxicity GO:0042267 29 0.040
positive regulation of interleukin 1 alpha secretion GO:0050717 3 0.040
regulation of angiotensin metabolic process GO:0060177 4 0.040
regulation of adaptive immune response GO:0002819 90 0.039
Mouse
regulation of endopeptidase activity GO:0052548 89 0.039
Human Mouse
regulation of b cell activation GO:0050864 81 0.039
regulation of homeostatic process GO:0032844 182 0.039
Mouse
regulation of inflammatory response GO:0050727 147 0.039
Mouse
cellular amino acid metabolic process GO:0006520 103 0.039
positive regulation of cell killing GO:0031343 33 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.039
regulation of body fluid levels GO:0050878 162 0.039
endocytosis GO:0006897 168 0.039
Fly
negative regulation of cellular component organization GO:0051129 194 0.038
positive regulation of mapk cascade GO:0043410 170 0.038
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.038
cellular response to hormone stimulus GO:0032870 150 0.038
regulation of kinase activity GO:0043549 249 0.038
Mouse
regulation of secretion by cell GO:1903530 249 0.038
Mouse
nucleotide catabolic process GO:0009166 217 0.038
positive regulation of leukocyte differentiation GO:1902107 86 0.038
Mouse
regulation of ion transport GO:0043269 215 0.038
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.038
purine containing compound metabolic process GO:0072521 311 0.038
cell adhesion GO:0007155 329 0.038
positive regulation of immunological synapse formation GO:2000522 1 0.038
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.038
Mouse
regulation of tumor necrosis factor production GO:0032680 49 0.037
monocyte extravasation GO:0035696 2 0.037
organonitrogen compound catabolic process GO:1901565 264 0.037
purine nucleotide metabolic process GO:0006163 302 0.037
heterocycle catabolic process GO:0046700 280 0.037
regulation of intracellular protein transport GO:0033157 82 0.037
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.037
Mouse
regulation of nucleocytoplasmic transport GO:0046822 73 0.037
Mouse
regulation of cytokine biosynthetic process GO:0042035 59 0.036
negative regulation of viral release from host cell GO:1902187 6 0.036
response to interferon beta GO:0035456 22 0.036
positive regulation of programmed cell death GO:0043068 218 0.036
Human Mouse
positive regulation of t cell extravasation GO:2000409 2 0.036
regulation of leukocyte mediated immunity GO:0002703 104 0.036
Mouse
regulation of lymphocyte apoptotic process GO:0070228 41 0.035
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.035
purine nucleoside triphosphate metabolic process GO:0009144 226 0.035
multicellular organismal homeostasis GO:0048871 164 0.035
Mouse
positive regulation of cytokine secretion GO:0050715 41 0.035
positive regulation of actin nucleation GO:0051127 3 0.034
response to radiation GO:0009314 165 0.034
anatomical structure homeostasis GO:0060249 145 0.034
Mouse Fly
regulation of protein complex assembly GO:0043254 83 0.034
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.034
single organism nuclear import GO:1902593 95 0.034
Mouse
regulation of alpha beta t cell activation GO:0046634 53 0.034
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.034
regulation of monocyte extravasation GO:2000437 2 0.034
positive regulation of proteolysis GO:0045862 85 0.034
Human Mouse
cellular calcium ion homeostasis GO:0006874 119 0.033
cellular response to interferon gamma GO:0071346 25 0.033
lymphocyte activation involved in immune response GO:0002285 93 0.033
Mouse
response to endoplasmic reticulum stress GO:0034976 53 0.033
regulation of cytoplasmic transport GO:1903649 112 0.033
Mouse
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.033
Human
negative regulation of intracellular protein transport GO:0090317 27 0.033
organic anion transport GO:0015711 137 0.033
Mouse
protein secretion GO:0009306 111 0.032
Mouse
negative regulation of viral process GO:0048525 23 0.032
leukocyte activation involved in immune response GO:0002366 126 0.032
Mouse
regulation of cellular catabolic process GO:0031329 242 0.032
negative regulation of nervous system development GO:0051961 156 0.032
pyroptosis GO:0070269 8 0.032
protein polyubiquitination GO:0000209 33 0.032
regulation of immunological synapse formation GO:2000520 2 0.031
protein localization to organelle GO:0033365 185 0.031
Mouse
amine metabolic process GO:0009308 45 0.031
cellular ion homeostasis GO:0006873 165 0.031
compound eye development GO:0048749 1 0.031
positive regulation of apoptotic process GO:0043065 217 0.030
Human Mouse
chemotaxis GO:0006935 247 0.030
Mouse
ear development GO:0043583 200 0.030
natural killer cell mediated immunity GO:0002228 29 0.030
negative regulation of eosinophil degranulation GO:0043310 1 0.030
regulation of transferase activity GO:0051338 263 0.030
Mouse
chemokine mediated signaling pathway GO:0070098 17 0.030
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.030
leukocyte mediated immunity GO:0002443 174 0.030
Mouse
maintenance of location GO:0051235 89 0.029
glycoprotein biosynthetic process GO:0009101 89 0.029
purine containing compound catabolic process GO:0072523 213 0.029
regulation of protein kinase activity GO:0045859 232 0.029
Mouse
regulation of protein processing GO:0070613 96 0.029
second messenger mediated signaling GO:0019932 73 0.029
regulation of neuron apoptotic process GO:0043523 122 0.029
antigen processing and presentation of endogenous peptide antigen via mhc class ib GO:0002476 4 0.028
gland development GO:0048732 330 0.028
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.028
Mouse
positive regulation of t cell costimulation GO:2000525 2 0.028
regulation of membrane potential GO:0042391 192 0.028
response to molecule of fungal origin GO:0002238 4 0.028
regulation of actin nucleation GO:0051125 4 0.028
reactive nitrogen species metabolic process GO:2001057 0 0.028
regulation of leukocyte differentiation GO:1902105 159 0.028
Mouse
cellular metal ion homeostasis GO:0006875 151 0.027
positive regulation of alpha beta t cell activation GO:0046635 39 0.027
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.027
natural killer cell proliferation GO:0001787 3 0.027
regulation of cellular component biogenesis GO:0044087 181 0.027
t helper 17 cell chemotaxis GO:0035705 1 0.027
regulation of eosinophil degranulation GO:0043309 1 0.027
cellular response to organic cyclic compound GO:0071407 87 0.027
g protein coupled receptor signaling pathway GO:0007186 243 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
regulation of viral transcription GO:0046782 3 0.026
negative regulation of kinase activity GO:0033673 81 0.026
lymphocyte apoptotic process GO:0070227 54 0.026
cell recognition GO:0008037 83 0.026
positive regulation of chemotaxis GO:0050921 38 0.026
Mouse
regulation of proteolysis GO:0030162 164 0.026
Human Mouse
positive regulation of interferon gamma production GO:0032729 39 0.026
Mouse
regulation of protein secretion GO:0050708 82 0.026
Mouse
single organism cell adhesion GO:0098602 156 0.026
nucleoside triphosphate metabolic process GO:0009141 230 0.026
multicellular organismal signaling GO:0035637 91 0.026
interferon beta production GO:0032608 16 0.026
regulation of viral release from host cell GO:1902186 6 0.026
cytosolic calcium ion transport GO:0060401 48 0.026
negative regulation of transferase activity GO:0051348 85 0.025
regulation of necroptotic process GO:0060544 10 0.025
regulation of angiotensin levels in blood GO:0002002 4 0.025
regulation of blood pressure GO:0008217 93 0.025
regulation of organelle organization GO:0033043 289 0.025
Human
regulation of interleukin 4 biosynthetic process GO:0045402 3 0.025
autophagy GO:0006914 45 0.025
cellular homeostasis GO:0019725 240 0.025
Fly
positive regulation of organelle organization GO:0010638 128 0.025
Human
phagocytosis GO:0006909 66 0.025
Fly
nuclear import GO:0051170 95 0.025
Mouse
morphogenesis of a branching structure GO:0001763 203 0.025
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.025
regulation of interleukin 10 secretion GO:2001179 4 0.025
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.025
Mouse
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.025
negative regulation of vasculature development GO:1901343 26 0.025
activation of cysteine type endopeptidase activity GO:0097202 27 0.025
Mouse
negative regulation of blood vessel morphogenesis GO:2000181 25 0.024
cellular lipid metabolic process GO:0044255 323 0.024
rho protein signal transduction GO:0007266 32 0.024
glycosyl compound catabolic process GO:1901658 206 0.024
ribonucleoside metabolic process GO:0009119 245 0.024
organophosphate biosynthetic process GO:0090407 122 0.024
positive regulation of interferon alpha production GO:0032727 4 0.024
negative regulation of protein processing GO:0010955 79 0.024
ossification GO:0001503 216 0.024
Mouse
tissue remodeling GO:0048771 102 0.024
Mouse
negative regulation of cell development GO:0010721 169 0.024
positive regulation of protein complex assembly GO:0031334 45 0.024
entry into host cell GO:0030260 15 0.024
interleukin 1 secretion GO:0050701 16 0.024
positive regulation of adaptive immune response GO:0002821 61 0.024
Mouse
cellular response to oxidative stress GO:0034599 76 0.024
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.023
regulation of chloride transport GO:2001225 2 0.023
positive regulation of camp mediated signaling GO:0043950 3 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
negative regulation of proteolysis GO:0045861 74 0.023
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
interleukin 12 secretion GO:0072610 3 0.023
glycoprotein metabolic process GO:0009100 116 0.023
negative regulation of necrotic cell death GO:0060547 11 0.023
sensory perception of mechanical stimulus GO:0050954 107 0.023
regulation of protein maturation GO:1903317 96 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.023
Mouse
eosinophil degranulation GO:0043308 1 0.023
protein targeting GO:0006605 143 0.023
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.022
negative regulation of lymphocyte activation GO:0051250 91 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
microglial cell activation involved in immune response GO:0002282 1 0.022
regulation of cellular response to stress GO:0080135 159 0.022
Mouse
epithelial cell proliferation GO:0050673 174 0.022
Mouse
peptide transport GO:0015833 133 0.022
Mouse
negative regulation of innate immune response GO:0045824 17 0.022
peptidyl amino acid modification GO:0018193 336 0.022
small gtpase mediated signal transduction GO:0007264 97 0.022
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.022
calcium ion homeostasis GO:0055074 127 0.022
Mouse
covalent chromatin modification GO:0016569 163 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
neutrophil migration GO:1990266 37 0.022
positive regulation of secretion by cell GO:1903532 114 0.022
Mouse
response to acid chemical GO:0001101 111 0.021
Mouse
mitotic cell cycle process GO:1903047 159 0.021
regulation of dendritic cell chemotaxis GO:2000508 1 0.021
t cell extravasation GO:0072683 4 0.021
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.021
regulation of cellular ketone metabolic process GO:0010565 66 0.021
positive regulation of protein localization to nucleus GO:1900182 30 0.021
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.021
Mouse
macrophage differentiation GO:0030225 20 0.021
nucleoside catabolic process GO:0009164 206 0.021
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.021
lymphocyte mediated immunity GO:0002449 139 0.021
Mouse
dna metabolic process GO:0006259 303 0.021
Mouse
striated muscle tissue development GO:0014706 293 0.021
Mouse
regulation of mitochondrial membrane potential GO:0051881 17 0.021
positive regulation of phospholipase c activity GO:0010863 2 0.021
negative regulation of response to wounding GO:1903035 77 0.021
organic acid biosynthetic process GO:0016053 86 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.021
positive regulation of phospholipase activity GO:0010518 3 0.021
nucleoside metabolic process GO:0009116 246 0.021
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.020
response to protozoan GO:0001562 28 0.020
regulation of cellular amino acid metabolic process GO:0006521 5 0.020
lipid transport GO:0006869 98 0.020
Mouse
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.020
t cell differentiation in thymus GO:0033077 77 0.020
cytosolic calcium ion homeostasis GO:0051480 70 0.020
regulation of lymphocyte differentiation GO:0045619 107 0.020
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.020
positive regulation of inflammatory response GO:0050729 47 0.020
Mouse
cellular response to drug GO:0035690 15 0.020
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.020
eosinophil mediated immunity GO:0002447 1 0.020
regulation of interleukin 1 beta production GO:0032651 25 0.020
cellularization GO:0007349 1 0.020
regulation of interleukin 2 production GO:0032663 28 0.020
purine nucleotide catabolic process GO:0006195 211 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
Mouse
stress activated protein kinase signaling cascade GO:0031098 81 0.019
Mouse Fly
wound healing GO:0042060 157 0.019
cellular ketone metabolic process GO:0042180 84 0.019
positive regulation of interleukin 1 secretion GO:0050716 14 0.019
positive regulation of monocyte chemotaxis GO:0090026 2 0.019
positive regulation of peptidase activity GO:0010952 49 0.019
Human Mouse
interleukin 10 secretion GO:0072608 4 0.019
negative regulation of nucleocytoplasmic transport GO:0046823 23 0.019
regulation of systemic arterial blood pressure GO:0003073 61 0.019
regulation of antimicrobial humoral response GO:0002759 3 0.019
chromatin organization GO:0006325 206 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
Human Mouse
multicellular organism growth GO:0035264 161 0.019
positive regulation of protein catabolic process GO:0045732 60 0.019
response to oxygen levels GO:0070482 62 0.019
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
regulation of myeloid cell differentiation GO:0045637 96 0.019
Mouse
interleukin 6 production GO:0032635 58 0.019
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
proteasomal protein catabolic process GO:0010498 98 0.019
regulation of secretion GO:0051046 274 0.019
Mouse
helper t cell chemotaxis GO:0035704 1 0.018
interleukin 2 biosynthetic process GO:0042094 15 0.018
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
regulation of stress activated mapk cascade GO:0032872 69 0.018
Mouse

Tnfsf10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.036
cancer DOID:162 0 0.031
organ system cancer DOID:0050686 0 0.031