Mus musculus

67 known processes

Tpm1

tropomyosin 1, alpha

(Aliases: AA986836,TM2,Tm3,Tmpa,Tpm-1,AI854628,alpha-TM)

Tpm1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin cytoskeleton organization GO:0030036 220 0.574
Worm
cellular component assembly involved in morphogenesis GO:0010927 139 0.454
muscle contraction GO:0006936 101 0.434
actomyosin structure organization GO:0031032 56 0.333
muscle system process GO:0003012 141 0.318
sarcomere organization GO:0045214 24 0.315
muscle cell development GO:0055001 133 0.246
cell adhesion GO:0007155 329 0.236
striated muscle cell development GO:0055002 125 0.235
muscle cell differentiation GO:0042692 261 0.233
organelle assembly GO:0070925 177 0.211
muscle tissue development GO:0060537 308 0.188
actin filament organization GO:0007015 113 0.165
Worm
striated muscle tissue development GO:0014706 293 0.145
single organismal cell cell adhesion GO:0016337 131 0.135
heart morphogenesis GO:0003007 178 0.124
regulation of anatomical structure size GO:0090066 178 0.120
Worm
heart contraction GO:0060047 93 0.101
negative regulation of phagocytosis GO:0050765 4 0.101
circulatory system process GO:0003013 197 0.101
macromolecule catabolic process GO:0009057 281 0.092
purine nucleotide metabolic process GO:0006163 302 0.092
heart process GO:0003015 94 0.090
regulation of cytoskeleton organization GO:0051493 122 0.089
Worm
wnt signaling pathway GO:0016055 188 0.089
wound healing GO:0042060 157 0.088
myosin filament organization GO:0031033 3 0.084
nucleobase containing small molecule metabolic process GO:0055086 352 0.084
cardiac muscle tissue development GO:0048738 130 0.082
blood circulation GO:0008015 195 0.081
myosin filament assembly GO:0031034 2 0.079
cation homeostasis GO:0055080 212 0.079
transmembrane transport GO:0055085 412 0.076
regulation of body fluid levels GO:0050878 162 0.075
coagulation GO:0050817 78 0.073
myofibril assembly GO:0030239 34 0.072
protein localization to organelle GO:0033365 185 0.071
regulation of hydrolase activity GO:0051336 246 0.071
blood coagulation GO:0007596 76 0.070
cardiac myofibril assembly GO:0055003 12 0.069
cellular divalent inorganic cation homeostasis GO:0072503 127 0.069
cell division GO:0051301 120 0.069
Worm
cellular chemical homeostasis GO:0055082 215 0.068
cell substrate adhesion GO:0031589 130 0.067
regulation of system process GO:0044057 200 0.066
cellular amine metabolic process GO:0044106 44 0.064
nucleotide metabolic process GO:0009117 332 0.063
regulation of cellular ketone metabolic process GO:0010565 66 0.063
cation transport GO:0006812 399 0.063
metal ion homeostasis GO:0055065 189 0.061
regulation of cellular component biogenesis GO:0044087 181 0.060
Worm Fly
regulation of mapk cascade GO:0043408 248 0.059
cellular homeostasis GO:0019725 240 0.059
regulation of actin filament based process GO:0032970 99 0.059
Worm
organic cyclic compound catabolic process GO:1901361 295 0.059
regulation of cell motility GO:2000145 236 0.059
cellular metal ion homeostasis GO:0006875 151 0.059
actin filament depolymerization GO:0030042 15 0.058
Worm
skeletal myofibril assembly GO:0014866 4 0.058
maintenance of location GO:0051235 89 0.058
regulation of transferase activity GO:0051338 263 0.058
negative regulation of molecular function GO:0044092 258 0.057
hemostasis GO:0007599 78 0.057
cardiac muscle cell differentiation GO:0055007 69 0.056
nucleoside triphosphate catabolic process GO:0009143 205 0.056
divalent inorganic cation homeostasis GO:0072507 138 0.055
peptidyl amino acid modification GO:0018193 336 0.055
single organism cell adhesion GO:0098602 156 0.055
regulation of organelle organization GO:0033043 289 0.055
Worm
mapk cascade GO:0000165 281 0.054
digestive tract morphogenesis GO:0048546 147 0.054
cardiocyte differentiation GO:0035051 87 0.054
nucleoside metabolic process GO:0009116 246 0.054
cellular nitrogen compound catabolic process GO:0044270 280 0.053
negative regulation of phosphorus metabolic process GO:0010563 184 0.052
ion transmembrane transport GO:0034220 361 0.052
positive regulation of protein kinase activity GO:0045860 144 0.052
platelet activation GO:0030168 40 0.051
cytoplasmic transport GO:0016482 234 0.051
regulation of actin cytoskeleton organization GO:0032956 84 0.051
Worm
ribonucleotide catabolic process GO:0009261 208 0.051
positive regulation of apoptotic process GO:0043065 217 0.050
regulation of cell adhesion GO:0030155 154 0.050
regulation of protein kinase activity GO:0045859 232 0.050
ribose phosphate metabolic process GO:0019693 291 0.049
cellular amino acid metabolic process GO:0006520 103 0.048
cellular calcium ion homeostasis GO:0006874 119 0.047
microtubule cytoskeleton organization GO:0000226 157 0.046
regulation of cell growth GO:0001558 91 0.046
dendritic spine organization GO:0097061 26 0.046
regulation of neuron projection development GO:0010975 169 0.046
actin filament based movement GO:0030048 23 0.045
cardiac muscle contraction GO:0060048 32 0.045
negative regulation of actin filament depolymerization GO:0030835 9 0.044
Worm
regulation of cell projection organization GO:0031344 206 0.044
Fly
muscle fiber development GO:0048747 76 0.043
protein catabolic process GO:0030163 221 0.043
regulation of cellular component size GO:0032535 121 0.043
Worm
cell growth GO:0016049 130 0.043
guanosine containing compound catabolic process GO:1901069 144 0.043
synaptic transmission GO:0007268 329 0.042
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.042
t cell activation GO:0042110 289 0.042
aromatic compound catabolic process GO:0019439 286 0.042
regulation of actin filament length GO:0030832 45 0.042
Worm
endocytosis GO:0006897 168 0.041
striated muscle contraction GO:0006941 45 0.041
negative regulation of phosphorylation GO:0042326 166 0.041
positive regulation of protein phosphorylation GO:0001934 242 0.041
calcium ion homeostasis GO:0055074 127 0.041
purine nucleoside triphosphate metabolic process GO:0009144 226 0.040
mitotic cell cycle process GO:1903047 159 0.040
organophosphate catabolic process GO:0046434 232 0.039
organic anion transport GO:0015711 137 0.039
apical constriction GO:0003383 4 0.039
anion transport GO:0006820 177 0.039
divalent metal ion transport GO:0070838 172 0.039
nucleoside catabolic process GO:0009164 206 0.038
skeletal muscle organ development GO:0060538 163 0.038
cardiac cell development GO:0055006 41 0.038
heterocycle catabolic process GO:0046700 280 0.038
cellular ion homeostasis GO:0006873 165 0.037
homotypic cell cell adhesion GO:0034109 28 0.037
myotube differentiation GO:0014902 105 0.037
platelet aggregation GO:0070527 20 0.037
regulation of cellular amine metabolic process GO:0033238 20 0.037
regulation of blood circulation GO:1903522 93 0.037
regulation of actin polymerization or depolymerization GO:0008064 45 0.037
Worm
purine containing compound metabolic process GO:0072521 311 0.037
positive regulation of cell death GO:0010942 224 0.036
regulation of purine nucleotide metabolic process GO:1900542 169 0.036
glycosyl compound metabolic process GO:1901657 246 0.036
apoptotic signaling pathway GO:0097190 306 0.035
myeloid cell differentiation GO:0030099 233 0.035
negative regulation of cell proliferation GO:0008285 296 0.035
regulation of cellular amino acid metabolic process GO:0006521 5 0.035
cardiac muscle cell development GO:0055013 39 0.035
protein localization to nucleus GO:0034504 121 0.035
cellular protein complex assembly GO:0043623 116 0.035
Worm
positive regulation of protein modification process GO:0031401 299 0.035
protein targeting GO:0006605 143 0.035
connective tissue development GO:0061448 179 0.035
carboxylic acid transport GO:0046942 100 0.034
membrane organization GO:0061024 245 0.034
phagocytosis GO:0006909 66 0.034
amine metabolic process GO:0009308 45 0.034
positive regulation of cellular amine metabolic process GO:0033240 5 0.034
striated muscle myosin thick filament assembly GO:0071688 1 0.033
engulfment of apoptotic cell GO:0043652 3 0.033
divalent inorganic cation transport GO:0072511 178 0.033
ribonucleoside triphosphate catabolic process GO:0009203 199 0.032
leukocyte differentiation GO:0002521 342 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
leukocyte proliferation GO:0070661 172 0.032
purine ribonucleotide metabolic process GO:0009150 290 0.032
cell matrix adhesion GO:0007160 68 0.032
digestive tract development GO:0048565 190 0.032
Worm
response to organic cyclic compound GO:0014070 198 0.031
gastrulation GO:0007369 116 0.031
negative regulation of cellular component organization GO:0051129 194 0.031
Worm
regulation of endocytosis GO:0030100 69 0.031
monocarboxylic acid metabolic process GO:0032787 191 0.031
adult behavior GO:0030534 135 0.031
response to muscle inactivity involved in regulation of muscle adaptation GO:0014877 4 0.031
response to inorganic substance GO:0010035 96 0.030
purine containing compound catabolic process GO:0072523 213 0.030
regulation of membrane potential GO:0042391 192 0.030
nuclear transport GO:0051169 139 0.030
regionalization GO:0003002 337 0.030
Fly
camera type eye development GO:0043010 266 0.030
inorganic ion transmembrane transport GO:0098660 234 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
muscle tissue morphogenesis GO:0060415 53 0.030
organonitrogen compound biosynthetic process GO:1901566 192 0.030
ras protein signal transduction GO:0007265 77 0.030
skeletal muscle thin filament assembly GO:0030240 2 0.030
regulation of ion transport GO:0043269 215 0.029
regulation of heart contraction GO:0008016 77 0.029
developmental growth involved in morphogenesis GO:0060560 138 0.029
negative regulation of protein phosphorylation GO:0001933 126 0.029
dendrite development GO:0016358 115 0.029
Fly
regulation of binding GO:0051098 111 0.029
Worm
response to peptide hormone GO:0043434 127 0.029
sequestering of calcium ion GO:0051208 18 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
lymphocyte proliferation GO:0046651 164 0.028
regulation of nucleoside metabolic process GO:0009118 130 0.028
purine ribonucleotide catabolic process GO:0009154 208 0.028
t cell proliferation GO:0042098 120 0.028
response to acid chemical GO:0001101 111 0.028
oxidation reduction process GO:0055114 342 0.028
ribonucleotide metabolic process GO:0009259 291 0.028
inorganic cation transmembrane transport GO:0098662 207 0.028
ribonucleoside metabolic process GO:0009119 245 0.028
regulation of intracellular transport GO:0032386 159 0.027
regulation of cell cycle process GO:0010564 160 0.027
regulation of cell activation GO:0050865 289 0.027
intracellular protein transport GO:0006886 204 0.027
regulation of cell migration GO:0030334 219 0.027
synapse organization GO:0050808 125 0.027
protein depolymerization GO:0051261 34 0.027
Worm
cellular ketone metabolic process GO:0042180 84 0.026
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
cellular protein complex disassembly GO:0043624 36 0.026
Worm
locomotory behavior GO:0007626 195 0.026
regulation of intracellular protein transport GO:0033157 82 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
positive regulation of cell development GO:0010720 237 0.026
organic acid transport GO:0015849 101 0.026
regulation of cellular catabolic process GO:0031329 242 0.026
angiogenesis GO:0001525 201 0.026
gtp metabolic process GO:0046039 144 0.025
actin mediated cell contraction GO:0070252 15 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.025
regulation of protein localization GO:0032880 231 0.025
regulation of vesicle mediated transport GO:0060627 139 0.025
regulation of blood pressure GO:0008217 93 0.025
regulation of kinase activity GO:0043549 249 0.025
regulation of establishment of protein localization GO:0070201 181 0.025
epithelial cell development GO:0002064 159 0.025
g protein coupled receptor signaling pathway GO:0007186 243 0.025
dna metabolic process GO:0006259 303 0.025
response to muscle stretch GO:0035994 1 0.024
lipid biosynthetic process GO:0008610 179 0.024
nucleoside triphosphate metabolic process GO:0009141 230 0.024
nucleoside phosphate metabolic process GO:0006753 338 0.024
pole plasm assembly GO:0007315 2 0.024
Fly
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
regulation of cell cycle GO:0051726 281 0.024
actin polymerization or depolymerization GO:0008154 54 0.024
Worm
positive regulation of nucleotide metabolic process GO:0045981 114 0.024
carbohydrate derivative biosynthetic process GO:1901137 183 0.024
endomembrane system organization GO:0010256 147 0.024
jnk cascade GO:0007254 72 0.023
organophosphate biosynthetic process GO:0090407 122 0.023
regulation of microtubule based process GO:0032886 52 0.023
developmental cell growth GO:0048588 84 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
small gtpase mediated signal transduction GO:0007264 97 0.023
positive regulation of hydrolase activity GO:0051345 148 0.023
blood vessel morphogenesis GO:0048514 285 0.023
glycosyl compound catabolic process GO:1901658 206 0.023
regulation of apoptotic signaling pathway GO:2001233 197 0.023
small molecule biosynthetic process GO:0044283 132 0.023
carboxylic acid biosynthetic process GO:0046394 86 0.023
negative regulation of cell development GO:0010721 169 0.022
smooth muscle contraction GO:0006939 44 0.022
regulation of wnt signaling pathway GO:0030111 123 0.022
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.022
regulation of muscle system process GO:0090257 80 0.022
transmission of nerve impulse GO:0019226 76 0.022
cation transmembrane transport GO:0098655 266 0.022
homeostasis of number of cells GO:0048872 210 0.022
regulation of neuron differentiation GO:0045664 281 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
response to inactivity GO:0014854 4 0.022
multicellular organismal signaling GO:0035637 91 0.022
axonogenesis GO:0007409 274 0.022
regulation of cell substrate adhesion GO:0010810 73 0.021
regulation of cytoplasmic transport GO:1903649 112 0.021
action potential GO:0001508 78 0.021
nucleocytoplasmic transport GO:0006913 139 0.021
positive regulation of transferase activity GO:0051347 167 0.021
regulation of purine nucleotide catabolic process GO:0033121 122 0.021
cellular protein catabolic process GO:0044257 155 0.021
protein maturation GO:0051604 176 0.021
epithelial tube morphogenesis GO:0060562 303 0.021
positive regulation of kinase activity GO:0033674 155 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.021
establishment of protein localization to organelle GO:0072594 118 0.021
urogenital system development GO:0001655 261 0.021
calcium ion transport GO:0006816 159 0.021
response to organonitrogen compound GO:0010243 246 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
neural precursor cell proliferation GO:0061351 121 0.020
establishment of tissue polarity GO:0007164 28 0.020
positive regulation of cell migration GO:0030335 109 0.020
regulation of actin filament polymerization GO:0030833 38 0.020
Worm
positive regulation of cell adhesion GO:0045785 80 0.020
regulation of metal ion transport GO:0010959 106 0.020
epithelial cell morphogenesis GO:0003382 41 0.020
cardiac muscle tissue morphogenesis GO:0055008 44 0.020
ameboidal type cell migration GO:0001667 128 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.020
protein ubiquitination GO:0016567 171 0.020
immune effector process GO:0002252 321 0.019
mitotic cytokinesis GO:0000281 4 0.019
macromolecular complex disassembly GO:0032984 43 0.019
Worm
localization within membrane GO:0051668 4 0.019
cellular response to lipid GO:0071396 145 0.019
tube formation GO:0035148 140 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
regulation of transmembrane transport GO:0034762 128 0.019
male gamete generation GO:0048232 285 0.019
cell migration involved in gastrulation GO:0042074 13 0.019
response to growth factor GO:0070848 198 0.019
positive regulation of cell cycle GO:0045787 92 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
nitrogen compound transport GO:0071705 271 0.019
negative regulation of apoptotic signaling pathway GO:2001234 104 0.019
response to transforming growth factor beta GO:0071559 88 0.019
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
fat cell differentiation GO:0045444 160 0.018
sequestering of metal ion GO:0051238 19 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
protein localization to membrane GO:0072657 108 0.018
circadian regulation of gene expression GO:0032922 48 0.018
lymphocyte differentiation GO:0030098 242 0.018
positive regulation of proteolysis GO:0045862 85 0.018
cellular alcohol biosynthetic process GO:0044108 3 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
detection of abiotic stimulus GO:0009582 60 0.018
renal system development GO:0072001 225 0.018
positive regulation of growth GO:0045927 104 0.018
skeletal muscle fiber development GO:0048741 58 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
stress activated protein kinase signaling cascade GO:0031098 81 0.017
lateral inhibition GO:0046331 1 0.017
positive regulation of nervous system development GO:0051962 221 0.017
positive regulation of endopeptidase activity GO:0010950 43 0.017
regulation of phagocytosis GO:0050764 33 0.017
positive regulation of cellular component biogenesis GO:0044089 94 0.017
regulation of gtp catabolic process GO:0033124 113 0.017
gtp catabolic process GO:0006184 143 0.017
negative regulation of organelle organization GO:0010639 90 0.017
Worm
reactive nitrogen species metabolic process GO:2001057 0 0.017
oocyte construction GO:0007308 2 0.017
Fly
nephron development GO:0072006 109 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
cytokine production GO:0001816 319 0.017
extrinsic apoptotic signaling pathway GO:0097191 126 0.017
rhythmic process GO:0048511 174 0.017
peripheral nervous system axon regeneration GO:0014012 2 0.017
microtubule based process GO:0007017 236 0.016
cell fate commitment GO:0045165 210 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
neuromuscular process GO:0050905 99 0.016
regulation of nucleocytoplasmic transport GO:0046822 73 0.016
neuron projection extension GO:1990138 64 0.016
regulation of homeostatic process GO:0032844 182 0.016
chronological cell aging GO:0001300 1 0.016
positive regulation of cell projection organization GO:0031346 95 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
modification dependent protein catabolic process GO:0019941 133 0.016
extracellular structure organization GO:0043062 148 0.016
mesoderm development GO:0007498 100 0.016
organic acid biosynthetic process GO:0016053 86 0.016
integrin mediated signaling pathway GO:0007229 27 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.016
development of primary sexual characteristics GO:0045137 143 0.016
Worm
positive regulation of neuron differentiation GO:0045666 141 0.016
cellular response to organic cyclic compound GO:0071407 87 0.016
cell type specific apoptotic process GO:0097285 268 0.015
multicellular organism growth GO:0035264 161 0.015
positive regulation of cell substrate adhesion GO:0010811 47 0.015
canonical wnt signaling pathway GO:0060070 130 0.015
fibrinolysis GO:0042730 3 0.015
detection of mechanical stimulus GO:0050982 27 0.015
regulation of defense response GO:0031347 233 0.015
negative regulation of intracellular transport GO:0032387 38 0.015
stress activated mapk cascade GO:0051403 80 0.015
neuronal action potential GO:0019228 54 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
neuron death GO:0070997 154 0.015
cellular lipid metabolic process GO:0044255 323 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
cardiac chamber development GO:0003205 108 0.015
extracellular matrix organization GO:0030198 147 0.015
regulation of hormone levels GO:0010817 211 0.015
cell aging GO:0007569 35 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.015
neuron apoptotic process GO:0051402 142 0.015
atp catabolic process GO:0006200 55 0.015
developmental maturation GO:0021700 193 0.015
Fly
negative regulation of kinase activity GO:0033673 81 0.015
multi multicellular organism process GO:0044706 109 0.015
Worm
mitotic cell cycle GO:0000278 195 0.015
adult locomotory behavior GO:0008344 91 0.014
meiotic cell cycle GO:0051321 122 0.014
tissue homeostasis GO:0001894 115 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.014
compound eye development GO:0048749 1 0.014
organelle localization GO:0051640 179 0.014
peptidyl proline hydroxylation GO:0019511 3 0.014
regulation of protein transport GO:0051223 163 0.014
retrograde transport endosome to golgi GO:0042147 2 0.014
skeletal system development GO:0001501 356 0.014
microtubule based movement GO:0007018 84 0.014
single organism nuclear import GO:1902593 95 0.014
positive regulation of cell cycle process GO:0090068 61 0.014
regulation of secretion GO:0051046 274 0.014
forebrain development GO:0030900 302 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
response to oxygen levels GO:0070482 62 0.014
spermatogenesis GO:0007283 284 0.014
peptide transport GO:0015833 133 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
regulation of actin filament depolymerization GO:0030834 13 0.014
Worm
inter male aggressive behavior GO:0002121 3 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
meiotic nuclear division GO:0007126 115 0.014
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
establishment of planar polarity GO:0001736 28 0.014
asymmetric stem cell division GO:0098722 3 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
negative regulation of cell motility GO:2000146 61 0.014
positive regulation of binding GO:0051099 49 0.014
regulation of transporter activity GO:0032409 57 0.014
mesodermal cell migration GO:0008078 4 0.014
regulation of lymphocyte activation GO:0051249 240 0.013
regulation of map kinase activity GO:0043405 120 0.013
response to alcohol GO:0097305 48 0.013
negative regulation of protein complex disassembly GO:0043242 22 0.013
Worm
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.013
cellular response to acid chemical GO:0071229 68 0.013
actin filament polymerization GO:0030041 44 0.013
Worm
carbohydrate metabolic process GO:0005975 230 0.013
lipid localization GO:0010876 126 0.013
mitochondrion distribution GO:0048311 4 0.013
placenta development GO:0001890 140 0.013
cofactor metabolic process GO:0051186 80 0.013
regulation of ossification GO:0030278 112 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
substrate adhesion dependent cell spreading GO:0034446 30 0.013
protein import GO:0017038 101 0.013
calcium ion transmembrane transport GO:0070588 85 0.013
kidney development GO:0001822 213 0.013
nuclear import GO:0051170 95 0.013
mitochondrion organization GO:0007005 134 0.013
regulation of ion homeostasis GO:2000021 64 0.013
nuclear division GO:0000280 158 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
i kappab kinase nf kappab signaling GO:0007249 85 0.013
exocytosis GO:0006887 121 0.013
respiratory tube development GO:0030323 167 0.013
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
glycoprotein metabolic process GO:0009100 116 0.013
regulation of protein depolymerization GO:1901879 26 0.013
Worm
response to radiation GO:0009314 165 0.013
learning or memory GO:0007611 148 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
generation of precursor metabolites and energy GO:0006091 103 0.013
rna processing GO:0006396 105 0.013
regulation of synaptic plasticity GO:0048167 87 0.013
sensory perception GO:0007600 245 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
acetylcholine transport GO:0015870 2 0.012
negative regulation of cytoskeleton organization GO:0051494 36 0.012
Worm
cellular response to organonitrogen compound GO:0071417 145 0.012
response to metal ion GO:0010038 47 0.012
positive regulation of cell motility GO:2000147 116 0.012
regulation of engulfment of apoptotic cell GO:1901074 2 0.012
inflammatory response GO:0006954 244 0.012
amide transport GO:0042886 138 0.012
nucleotide catabolic process GO:0009166 217 0.012
plasma membrane organization GO:0007009 90 0.012
regulation of synapse structural plasticity GO:0051823 4 0.012
cellular alcohol metabolic process GO:0044107 3 0.012
protein polymerization GO:0051258 57 0.012
Worm
muscle cell fate specification GO:0042694 1 0.012
negative regulation of protein modification process GO:0031400 163 0.012
cell cell junction organization GO:0045216 72 0.012
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
cytosolic calcium ion homeostasis GO:0051480 70 0.012
regulation of protein binding GO:0043393 60 0.012
Worm
regulation of ion transmembrane transporter activity GO:0032412 54 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
establishment or maintenance of cell polarity GO:0007163 86 0.012
morphogenesis of a polarized epithelium GO:0001738 37 0.012
regulation of cell cycle phase transition GO:1901987 77 0.012

Tpm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.023
muscular disease DOID:0080000 0 0.023
heart disease DOID:114 0 0.023
cardiomyopathy DOID:0050700 0 0.023
disease of anatomical entity DOID:7 0 0.023
cardiovascular system disease DOID:1287 0 0.023
musculoskeletal system disease DOID:17 0 0.023
muscle tissue disease DOID:66 0 0.023
nervous system disease DOID:863 0 0.019
bone development disease DOID:0080006 0 0.018
bone disease DOID:0080001 0 0.018
connective tissue disease DOID:65 0 0.018
intrinsic cardiomyopathy DOID:0060036 0 0.016