Mus musculus

91 known processes

Trem3

triggering receptor expressed on myeloid cells 3

(Aliases: BB134760)

Trem3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response to other organism GO:0098542 197 0.938
negative regulation of serotonin secretion GO:0014063 2 0.832
serotonin secretion by mast cell GO:0002552 1 0.791
positive regulation of cytokine secretion GO:0050715 41 0.778
positive regulation of toll like receptor 9 signaling pathway GO:0034165 2 0.744
detection of fungus GO:0016046 2 0.739
immunoglobulin transcytosis in epithelial cells GO:0002414 2 0.736
regulation of cytokine production GO:0001817 266 0.712
regulation of defense response GO:0031347 233 0.708
cellular response to peptidoglycan GO:0071224 4 0.675
cellular response to lipopolysaccharide GO:0071222 77 0.649
myeloid cell differentiation GO:0030099 233 0.616
negative regulation of immune system process GO:0002683 209 0.613
myeloid leukocyte mediated immunity GO:0002444 42 0.613
regulation of inflammatory response GO:0050727 147 0.609
response to molecule of bacterial origin GO:0002237 143 0.577
immune effector process GO:0002252 321 0.564
negative regulation of mast cell degranulation GO:0043305 4 0.556
positive regulation of cytokine production GO:0001819 174 0.536
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.526
cytokine production GO:0001816 319 0.511
leukocyte mediated immunity GO:0002443 174 0.507
regulation of leukocyte mediated immunity GO:0002703 104 0.489
response to lipopolysaccharide GO:0032496 128 0.462
regulation of innate immune response GO:0045088 91 0.458
defense response to bacterium GO:0042742 119 0.448
leukocyte migration GO:0050900 124 0.429
serotonin secretion involved in inflammatory response GO:0002442 4 0.414
regulation of mast cell activation GO:0033003 21 0.394
leukocyte activation involved in immune response GO:0002366 126 0.391
organic hydroxy compound transport GO:0015850 93 0.382
positive regulation of defense response GO:0031349 124 0.382
regulation of vesicle mediated transport GO:0060627 139 0.375
cell killing GO:0001906 67 0.374
regulation of secretion GO:0051046 274 0.374
leukocyte degranulation GO:0043299 27 0.362
nitrogen compound transport GO:0071705 271 0.340
regulation of multi organism process GO:0043900 111 0.339
positive regulation of cell migration GO:0030335 109 0.319
activation of innate immune response GO:0002218 56 0.314
g protein coupled receptor signaling pathway GO:0007186 243 0.313
cellular response to molecule of bacterial origin GO:0071219 83 0.310
detection of molecule of bacterial origin GO:0032490 2 0.308
immune response regulating signaling pathway GO:0002764 125 0.305
immune response activating signal transduction GO:0002757 116 0.300
pattern recognition receptor signaling pathway GO:0002221 47 0.280
t cell activation GO:0042110 289 0.279
negative regulation of leukocyte mediated immunity GO:0002704 29 0.271
cellular response to organonitrogen compound GO:0071417 145 0.268
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.263
regulation of cell motility GO:2000145 236 0.257
monoamine transport GO:0015844 33 0.256
regulation of cell migration GO:0030334 219 0.253
regulation of toll like receptor signaling pathway GO:0034121 20 0.248
cell activation involved in immune response GO:0002263 126 0.244
activation of mapk activity involved in innate immune response GO:0035419 2 0.243
toll like receptor signaling pathway GO:0002224 38 0.236
inflammatory response GO:0006954 244 0.234
leukocyte differentiation GO:0002521 342 0.233
defense response to gram positive bacterium GO:0050830 50 0.232
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.231
positive regulation of immune effector process GO:0002699 107 0.231
detection of peptidoglycan GO:0032499 1 0.230
positive regulation of protein transport GO:0051222 93 0.229
regulation of serotonin secretion GO:0014062 3 0.228
lymphocyte mediated immunity GO:0002449 139 0.228
positive regulation of innate immune response GO:0045089 80 0.227
detection of biotic stimulus GO:0009595 10 0.222
killing of cells of other organism GO:0031640 13 0.222
wound healing GO:0042060 157 0.217
negative regulation of immune effector process GO:0002698 55 0.211
regulation of cell activation GO:0050865 289 0.209
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.207
regulation of regulated secretory pathway GO:1903305 20 0.204
regulation of exocytosis GO:0017157 61 0.201
action potential GO:0001508 78 0.200
myeloid leukocyte differentiation GO:0002573 119 0.199
protein secretion GO:0009306 111 0.198
regulation of response to wounding GO:1903034 189 0.197
regulation of secretion by cell GO:1903530 249 0.194
chemotaxis GO:0006935 247 0.187
purinergic receptor signaling pathway GO:0035587 7 0.187
myeloid leukocyte activation GO:0002274 83 0.184
regulation of hormone levels GO:0010817 211 0.183
innate immune response GO:0045087 157 0.181
mast cell activation involved in immune response GO:0002279 20 0.179
striated muscle tissue development GO:0014706 293 0.178
membrane organization GO:0061024 245 0.178
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.177
interspecies interaction between organisms GO:0044419 83 0.167
myeloid cell activation involved in immune response GO:0002275 34 0.166
cytokine secretion GO:0050663 72 0.165
innate immune response activating signal transduction GO:0002758 50 0.162
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.159
exocytosis GO:0006887 121 0.154
positive regulation of mapk cascade GO:0043410 170 0.153
regulation of lymphocyte proliferation GO:0050670 117 0.152
regulation of lymphocyte activation GO:0051249 240 0.149
serotonin production involved in inflammatory response GO:0002351 4 0.147
regulation of cellular amine metabolic process GO:0033238 20 0.145
mast cell activation GO:0045576 27 0.144
regulation of cellular amino acid metabolic process GO:0006521 5 0.142
cellular response to lipid GO:0071396 145 0.141
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.140
peptidyl amino acid modification GO:0018193 336 0.137
regulation of chemokine production GO:0032642 30 0.137
leukocyte proliferation GO:0070661 172 0.134
positive regulation of leukocyte mediated immunity GO:0002705 70 0.131
negative regulation of defense response GO:0031348 77 0.129
cellular amine metabolic process GO:0044106 44 0.129
regulation of lymphocyte mediated immunity GO:0002706 84 0.128
phagocytosis GO:0006909 66 0.127
negative regulation of regulated secretory pathway GO:1903306 7 0.127
positive regulation of secretion by cell GO:1903532 114 0.126
amide transport GO:0042886 138 0.126
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.125
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.125
neutrophil chemotaxis GO:0030593 36 0.123
peptide transport GO:0015833 133 0.122
negative regulation of cell proliferation GO:0008285 296 0.121
regulation of phagocytosis GO:0050764 33 0.121
interleukin 18 production GO:0032621 4 0.120
detection of yeast GO:0001879 2 0.119
endocytosis GO:0006897 168 0.115
negative regulation of cell activation GO:0050866 111 0.114
reactive oxygen species metabolic process GO:0072593 84 0.114
positive regulation of response to wounding GO:1903036 66 0.112
positive regulation of cellular amine metabolic process GO:0033240 5 0.111
positive regulation of leukocyte differentiation GO:1902107 86 0.110
mast cell mediated immunity GO:0002448 20 0.110
positive regulation of phagocytosis GO:0050766 26 0.110
negative regulation of mast cell activation involved in immune response GO:0033007 5 0.106
lymphocyte activation involved in immune response GO:0002285 93 0.106
tumor necrosis factor production GO:0032640 50 0.105
cellular response to biotic stimulus GO:0071216 92 0.104
production of molecular mediator of immune response GO:0002440 103 0.104
detection of external biotic stimulus GO:0098581 9 0.103
cell chemotaxis GO:0060326 81 0.103
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.102
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.099
hormone secretion GO:0046879 128 0.098
neutrophil mediated immunity GO:0002446 19 0.098
negative regulation of inflammatory response GO:0050728 61 0.098
regulation of protein localization GO:0032880 231 0.096
regulation of reactive oxygen species metabolic process GO:2000377 40 0.096
lymphocyte proliferation GO:0046651 164 0.095
positive regulation of chemotaxis GO:0050921 38 0.094
serotonin transport GO:0006837 11 0.092
reactive nitrogen species metabolic process GO:2001057 0 0.092
regulation of protein secretion GO:0050708 82 0.092
negative regulation of phagocytosis GO:0050765 4 0.091
positive regulation of leukocyte degranulation GO:0043302 10 0.090
regulation of cytokine secretion GO:0050707 61 0.090
granulocyte migration GO:0097530 43 0.090
adaptive immune response GO:0002250 155 0.089
cellular amino acid metabolic process GO:0006520 103 0.088
ossification GO:0001503 216 0.087
negative regulation of secretion GO:0051048 61 0.086
cell fate commitment GO:0045165 210 0.085
negative regulation of mast cell activation GO:0033004 6 0.084
single organismal cell cell adhesion GO:0016337 131 0.084
negative regulation of response to wounding GO:1903035 77 0.083
muscle tissue development GO:0060537 308 0.083
regulation of osteoclast differentiation GO:0045670 36 0.082
muscle cell differentiation GO:0042692 261 0.082
regulation of interferon gamma production GO:0032649 57 0.082
cellular ketone metabolic process GO:0042180 84 0.081
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.081
acute inflammatory response GO:0002526 41 0.080
negative regulation of cytokine production GO:0001818 84 0.080
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.079
amine metabolic process GO:0009308 45 0.079
positive regulation of apoptotic process GO:0043065 217 0.079
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.078
regulation of acute inflammatory response to non antigenic stimulus GO:0002877 2 0.078
calcium mediated signaling GO:0019722 46 0.078
regulation of mast cell degranulation GO:0043304 16 0.077
toll like receptor 9 signaling pathway GO:0034162 6 0.077
response to acid chemical GO:0001101 111 0.077
regulation of establishment of protein localization GO:0070201 181 0.077
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.076
tissue homeostasis GO:0001894 115 0.076
regulation of membrane potential GO:0042391 192 0.075
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.075
histamine transport GO:0051608 2 0.075
peptide secretion GO:0002790 114 0.074
interleukin 6 production GO:0032635 58 0.074
negative regulation of multi organism process GO:0043901 68 0.073
negative regulation of growth GO:0045926 99 0.073
osteoclast differentiation GO:0030316 62 0.073
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.072
positive regulation of cell death GO:0010942 224 0.071
positive regulation of cell motility GO:2000147 116 0.071
positive regulation of protein secretion GO:0050714 52 0.071
positive regulation of cell activation GO:0050867 158 0.071
carboxylic acid transport GO:0046942 100 0.070
phosphatidylinositol mediated signaling GO:0048015 41 0.070
negative regulation of nik nf kappab signaling GO:1901223 2 0.069
cytokine metabolic process GO:0042107 71 0.069
protein processing GO:0016485 163 0.069
regulation of leukocyte degranulation GO:0043300 20 0.068
response to organonitrogen compound GO:0010243 246 0.068
negative regulation of cellular protein metabolic process GO:0032269 247 0.067
interferon gamma production GO:0032609 67 0.067
peptidyl tyrosine phosphorylation GO:0018108 143 0.067
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.066
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.065
regulation of peptide transport GO:0090087 91 0.065
inositol lipid mediated signaling GO:0048017 41 0.064
protein modification by small protein conjugation or removal GO:0070647 207 0.064
regulation of protein transport GO:0051223 163 0.064
regulation of intracellular transport GO:0032386 159 0.063
cell type specific apoptotic process GO:0097285 268 0.063
regulation of tumor necrosis factor production GO:0032680 49 0.063
negative regulation of intracellular transport GO:0032387 38 0.062
defense response to virus GO:0051607 68 0.062
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.062
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.062
regulation of chemotaxis GO:0050920 53 0.062
positive regulation of transferase activity GO:0051347 167 0.061
extracellular matrix organization GO:0030198 147 0.060
glial cell differentiation GO:0010001 131 0.059
keratinocyte migration GO:0051546 3 0.059
negative regulation of secretion by cell GO:1903531 54 0.059
regulation of muscle tissue development GO:1901861 97 0.059
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.059
digestive tract development GO:0048565 190 0.058
activation of immune response GO:0002253 138 0.057
protein ubiquitination GO:0016567 171 0.057
anion transport GO:0006820 177 0.057
peptidyl tyrosine modification GO:0018212 145 0.056
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.056
antibacterial peptide production GO:0002778 2 0.056
serotonin secretion GO:0001820 8 0.055
modification of morphology or physiology of other organism GO:0035821 18 0.055
regulation of homeostatic process GO:0032844 182 0.054
histamine production involved in inflammatory response GO:0002349 1 0.054
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.054
response to growth factor GO:0070848 198 0.053
protein modification by small protein conjugation GO:0032446 187 0.053
negative regulation of interferon gamma production GO:0032689 18 0.053
reactive oxygen species biosynthetic process GO:1903409 8 0.052
regulation of ion transport GO:0043269 215 0.052
regulation of cell killing GO:0031341 40 0.051
amino acid transport GO:0006865 61 0.051
organic acid transport GO:0015849 101 0.051
cation homeostasis GO:0055080 212 0.051
natural killer cell activation GO:0030101 44 0.050
negative regulation of cellular component organization GO:0051129 194 0.050
negative regulation of lymphocyte activation GO:0051250 91 0.050
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.049
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.049
developmental maturation GO:0021700 193 0.049
positive regulation of exocytosis GO:0045921 20 0.049
second messenger mediated signaling GO:0019932 73 0.048
cellular response to hormone stimulus GO:0032870 150 0.048
insulin secretion GO:0030073 89 0.048
leukocyte chemotaxis GO:0030595 69 0.048
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.047
positive regulation of calcium mediated signaling GO:0050850 15 0.047
cell adhesion GO:0007155 329 0.047
regulation of cellular ketone metabolic process GO:0010565 66 0.047
regulation of myotube differentiation GO:0010830 62 0.046
regulation of cellular response to stress GO:0080135 159 0.046
ameboidal type cell migration GO:0001667 128 0.046
hexose transport GO:0008645 56 0.046
response to peptide GO:1901652 136 0.046
multicellular organismal homeostasis GO:0048871 164 0.046
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.046
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.046
regulation of cytokine biosynthetic process GO:0042035 59 0.045
transmission of nerve impulse GO:0019226 76 0.045
antimicrobial peptide production GO:0002775 2 0.045
t cell mediated immunity GO:0002456 50 0.045
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.045
synaptic transmission GO:0007268 329 0.045
mapk cascade GO:0000165 281 0.044
regulation of mast cell activation involved in immune response GO:0033006 17 0.044
organelle localization GO:0051640 179 0.044
circulatory system process GO:0003013 197 0.044
lysosome localization GO:0032418 20 0.043
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.043
anatomical structure homeostasis GO:0060249 145 0.043
regulation of striated muscle cell differentiation GO:0051153 81 0.043
regulation of t cell costimulation GO:2000523 2 0.043
regulation of t cell activation GO:0050863 170 0.043
response to peptidoglycan GO:0032494 9 0.043
ras protein signal transduction GO:0007265 77 0.042
detection of lipoteichoic acid GO:0070392 1 0.042
regulation of immunoglobulin mediated immune response GO:0002889 37 0.042
cation transport GO:0006812 399 0.042
positive regulation of secretion GO:0051047 130 0.042
stem cell differentiation GO:0048863 268 0.042
protein localization to organelle GO:0033365 185 0.042
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.042
positive regulation of regulated secretory pathway GO:1903307 10 0.042
organic anion transport GO:0015711 137 0.041
antibacterial peptide biosynthetic process GO:0002780 2 0.041
regulation of cell projection organization GO:0031344 206 0.041
organonitrogen compound biosynthetic process GO:1901566 192 0.041
positive regulation of protein modification process GO:0031401 299 0.041
negative regulation of toll like receptor 2 signaling pathway GO:0034136 3 0.041
regulation of cell cycle GO:0051726 281 0.041
cellular ion homeostasis GO:0006873 165 0.040
regulation of endocytosis GO:0030100 69 0.040
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 4 0.040
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.040
defense response to gram negative bacterium GO:0050829 28 0.040
regulated secretory pathway GO:0045055 32 0.040
divalent inorganic cation transport GO:0072511 178 0.040
production of molecular mediator involved in inflammatory response GO:0002532 21 0.040
nuclear transport GO:0051169 139 0.040
glucose homeostasis GO:0042593 128 0.040
erk1 and erk2 cascade GO:0070371 77 0.040
rho protein signal transduction GO:0007266 32 0.039
response to organic cyclic compound GO:0014070 198 0.039
regulation of hormone secretion GO:0046883 88 0.039
positive regulation of interleukin 8 production GO:0032757 2 0.039
regulation of protein kinase b signaling GO:0051896 56 0.038
blood circulation GO:0008015 195 0.038
monosaccharide transport GO:0015749 58 0.038
cellular response to acid chemical GO:0071229 68 0.038
regulation of mapk cascade GO:0043408 248 0.037
regulation of organ growth GO:0046620 61 0.037
protein kinase b signaling GO:0043491 74 0.037
posttranscriptional regulation of gene expression GO:0010608 155 0.037
cognition GO:0050890 149 0.037
chemokine metabolic process GO:0050755 10 0.037
small gtpase mediated signal transduction GO:0007264 97 0.037
endomembrane system organization GO:0010256 147 0.036
positive regulation of map kinase activity GO:0043406 84 0.036
regulation of proteolysis GO:0030162 164 0.036
regulation of blood pressure GO:0008217 93 0.036
extracellular structure organization GO:0043062 148 0.036
homeostasis of number of cells GO:0048872 210 0.036
cytokine biosynthetic process GO:0042089 68 0.036
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.036
b cell proliferation GO:0042100 53 0.036
regulation of anatomical structure size GO:0090066 178 0.036
neuronal action potential GO:0019228 54 0.036
regulation of interleukin 6 production GO:0032675 55 0.036
myeloid leukocyte migration GO:0097529 57 0.036
peptide hormone secretion GO:0030072 109 0.035
regulation of wound healing GO:0061041 40 0.035
regulation of toll like receptor 9 signaling pathway GO:0034163 3 0.035
leukocyte apoptotic process GO:0071887 71 0.035
carbohydrate metabolic process GO:0005975 230 0.034
neutrophil migration GO:1990266 37 0.034
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.034
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.034
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 3 0.034
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.034
negative regulation of t cell mediated immunity GO:0002710 9 0.034
negative regulation of leukocyte degranulation GO:0043301 7 0.034
regulation of osteoblast differentiation GO:0045667 67 0.034
natural killer cell mediated immunity GO:0002228 29 0.034
positive regulation of cell development GO:0010720 237 0.034
humoral immune response GO:0006959 57 0.034
granulocyte chemotaxis GO:0071621 39 0.034
aromatic compound catabolic process GO:0019439 286 0.033
detection of other organism GO:0098543 8 0.033
positive regulation of programmed cell death GO:0043068 218 0.033
mast cell degranulation GO:0043303 19 0.033
divalent metal ion transport GO:0070838 172 0.033
leukocyte mediated cytotoxicity GO:0001909 62 0.032
single organism cell adhesion GO:0098602 156 0.032
salivary gland development GO:0007431 37 0.032
fat cell differentiation GO:0045444 160 0.032
carbohydrate homeostasis GO:0033500 128 0.032
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.032
microtubule based process GO:0007017 236 0.031
kidney development GO:0001822 213 0.031
positive regulation of interferon gamma production GO:0032729 39 0.031
regulation of peptide hormone secretion GO:0090276 75 0.031
protein targeting GO:0006605 143 0.031
stem cell development GO:0048864 219 0.031
growth of symbiont involved in interaction with host GO:0044116 23 0.031
cellular response to peptide hormone stimulus GO:0071375 92 0.031
body fluid secretion GO:0007589 53 0.031
transepithelial chloride transport GO:0030321 4 0.031
regulation of wnt signaling pathway GO:0030111 123 0.031
multicellular organismal signaling GO:0035637 91 0.031
maintenance of location GO:0051235 89 0.031
odontogenesis of dentin containing tooth GO:0042475 66 0.031
metal ion homeostasis GO:0055065 189 0.031
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.031
t helper 17 cell chemotaxis GO:0035705 1 0.030
positive regulation of mast cell degranulation GO:0043306 10 0.030
innate immune response in mucosa GO:0002227 3 0.030
positive regulation of homeostatic process GO:0032846 64 0.030
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.030
t cell proliferation GO:0042098 120 0.030
cellular response to cytokine stimulus GO:0071345 189 0.030
regulation of cellular component biogenesis GO:0044087 181 0.030
transcytosis GO:0045056 5 0.030
response to extracellular stimulus GO:0009991 127 0.030
regulation of acute inflammatory response GO:0002673 27 0.030
cellular protein complex assembly GO:0043623 116 0.029
cellular response to organic cyclic compound GO:0071407 87 0.029
regulation of body fluid levels GO:0050878 162 0.029
skeletal muscle fiber development GO:0048741 58 0.029
skeletal system development GO:0001501 356 0.029
natural killer cell mediated cytotoxicity GO:0042267 29 0.029
positive regulation of lymphocyte proliferation GO:0050671 70 0.029
intracellular protein transport GO:0006886 204 0.028
nuclear import GO:0051170 95 0.028
regulation of endopeptidase activity GO:0052548 89 0.028
cerebral cortex development GO:0021987 86 0.028
negative regulation of lipid metabolic process GO:0045833 30 0.028
negative regulation of exocytosis GO:0045920 12 0.028
positive regulation of proteolysis GO:0045862 85 0.028
b cell activation GO:0042113 161 0.028
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.028
cytoplasmic transport GO:0016482 234 0.028
learning or memory GO:0007611 148 0.028
detection of lipopolysaccharide GO:0032497 1 0.027
respiratory tube development GO:0030323 167 0.027
sequestering of calcium ion GO:0051208 18 0.027
response to amino acid GO:0043200 37 0.027
cellular calcium ion homeostasis GO:0006874 119 0.027
hematopoietic progenitor cell differentiation GO:0002244 143 0.027
negative regulation of synapse assembly GO:0051964 3 0.027
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.027
regulation of antimicrobial humoral response GO:0002759 3 0.027
regulation of mucus secretion GO:0070255 11 0.026
calcium ion homeostasis GO:0055074 127 0.026
macromolecule catabolic process GO:0009057 281 0.026
cellular carbohydrate metabolic process GO:0044262 119 0.026
regulation of t cell proliferation GO:0042129 92 0.026
gliogenesis GO:0042063 141 0.026
cellular response to insulin stimulus GO:0032869 78 0.026
regulation of leukocyte proliferation GO:0070663 121 0.026
regulation of apoptotic signaling pathway GO:2001233 197 0.026
cellular response to peptide GO:1901653 92 0.026
membrane invagination GO:0010324 17 0.026
notch signaling pathway GO:0007219 71 0.026
calcium ion transport GO:0006816 159 0.026
regulation of production of molecular mediator of immune response GO:0002700 65 0.026
regulation of peptide secretion GO:0002791 77 0.026
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.026
cell growth GO:0016049 130 0.026
epithelial tube morphogenesis GO:0060562 303 0.025
organic hydroxy compound metabolic process GO:1901615 203 0.025
negative regulation of adaptive immune response GO:0002820 25 0.025
apoptotic signaling pathway GO:0097190 306 0.025
pallium development GO:0021543 120 0.025
cytokine production involved in immune response GO:0002367 34 0.025
regulation of neuron differentiation GO:0045664 281 0.025
growth involved in symbiotic interaction GO:0044110 23 0.025
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.025
exocrine system development GO:0035272 45 0.025
tumor necrosis factor biosynthetic process GO:0042533 10 0.025
positive regulation of cytokine biosynthetic process GO:0042108 40 0.024
positive regulation of intracellular transport GO:0032388 70 0.024
cellular response to growth factor stimulus GO:0071363 197 0.024
sensory perception of pain GO:0019233 47 0.024
skeletal muscle organ development GO:0060538 163 0.024
striated muscle cell development GO:0055002 125 0.024
coagulation GO:0050817 78 0.024
negative regulation of growth of symbiont in host GO:0044130 19 0.024
negative regulation of myeloid leukocyte mediated immunity GO:0002887 7 0.024
regulation of humoral immune response GO:0002920 22 0.024
telencephalon development GO:0021537 186 0.024
toll like receptor 7 signaling pathway GO:0034154 4 0.024
oxidation reduction process GO:0055114 342 0.024
mitotic cell cycle GO:0000278 195 0.024
interleukin 8 production GO:0032637 4 0.023
sensory perception GO:0007600 245 0.023
azole transport GO:0045117 6 0.023
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.023
organ growth GO:0035265 117 0.023
cellular response to steroid hormone stimulus GO:0071383 33 0.023
negative regulation of leukocyte proliferation GO:0070664 46 0.023
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.023
digestive system development GO:0055123 200 0.023
protein localization to nucleus GO:0034504 121 0.023
negative regulation of mapk cascade GO:0043409 65 0.023
glycoprotein biosynthetic process GO:0009101 89 0.023
chronic inflammatory response to antigenic stimulus GO:0002439 3 0.023
response to inorganic substance GO:0010035 96 0.023
response to insulin GO:0032868 100 0.023
positive regulation of kinase activity GO:0033674 155 0.023
regulation of prostaglandin endoperoxide synthase activity GO:0060584 2 0.023
glycoprotein metabolic process GO:0009100 116 0.023
muscle cell development GO:0055001 133 0.023
nk t cell proliferation GO:0001866 2 0.022
regulation of neutrophil migration GO:1902622 14 0.022
antimicrobial peptide biosynthetic process GO:0002777 2 0.022
cell maturation GO:0048469 127 0.022
regulation of calcium mediated signaling GO:0050848 19 0.022
positive regulation of endocytosis GO:0045807 42 0.022
blood vessel morphogenesis GO:0048514 285 0.022

Trem3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
acquired immunodeficiency syndrome DOID:635 0 0.039
disease by infectious agent DOID:0050117 0 0.039
viral infectious disease DOID:934 0 0.039
human immunodeficiency virus infectious disease DOID:526 0 0.039
disease of cellular proliferation DOID:14566 0 0.034
cancer DOID:162 0 0.028
organ system cancer DOID:0050686 0 0.028