Mus musculus

166 known processes

Trim28

tripartite motif-containing 28

(Aliases: KAP-1,Tif1b,Tif1beta,KRIP-1,AA408787,MGC102100)

Trim28 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone methylation GO:0016571 71 0.990
dna metabolic process GO:0006259 303 0.972
dna methylation GO:0006306 43 0.921
chromatin modification GO:0016568 187 0.919
histone h3 k9 dimethylation GO:0036123 4 0.899
chromatin organization GO:0006325 206 0.867
Fly
protein alkylation GO:0008213 81 0.855
purine nucleoside catabolic process GO:0006152 205 0.841
dna hypermethylation GO:0044026 3 0.836
cellular response to dna damage stimulus GO:0006974 207 0.832
Human
regulation of histone methylation GO:0031060 30 0.815
macromolecule methylation GO:0043414 120 0.806
regulation of transcription by chromatin organization GO:0034401 0 0.798
histone lysine methylation GO:0034968 50 0.794
negative regulation of mrna processing GO:0050686 12 0.773
glycosyl compound metabolic process GO:1901657 246 0.749
dna modification GO:0006304 50 0.744
dna repair GO:0006281 107 0.686
Human
nucleoside metabolic process GO:0009116 246 0.666
purine nucleoside triphosphate catabolic process GO:0009146 203 0.665
histone modification GO:0016570 159 0.646
covalent chromatin modification GO:0016569 163 0.645
mitotic cell cycle GO:0000278 195 0.642
spermatogenesis GO:0007283 284 0.629
intracellular receptor signaling pathway GO:0030522 74 0.610
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.606
Human Mouse
histone deubiquitination GO:0016578 2 0.580
positive regulation of histone methylation GO:0031062 16 0.569
dna alkylation GO:0006305 43 0.556
gene silencing GO:0016458 38 0.544
positive regulation of protein modification process GO:0031401 299 0.536
chromatin assembly GO:0031497 13 0.535
amine metabolic process GO:0009308 45 0.533
methylation GO:0032259 134 0.530
regulation of histone h3 k9 methylation GO:0051570 8 0.518
small gtpase mediated signal transduction GO:0007264 97 0.513
regulation of chromatin modification GO:1903308 57 0.504
regulation of histone modification GO:0031056 56 0.501
protein methylation GO:0006479 81 0.493
ribonucleoside metabolic process GO:0009119 245 0.469
histone h3 k9 methylation GO:0051567 17 0.458
regulation of cell cycle GO:0051726 281 0.451
regulation of cellular ketone metabolic process GO:0010565 66 0.448
purine containing compound metabolic process GO:0072521 311 0.442
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.441
chromatin assembly or disassembly GO:0006333 16 0.433
cellular nitrogen compound catabolic process GO:0044270 280 0.399
mrna splicing via spliceosome GO:0000398 43 0.397
ribonucleotide catabolic process GO:0009261 208 0.387
regulation of cellular amino acid metabolic process GO:0006521 5 0.385
nucleobase containing small molecule metabolic process GO:0055086 352 0.368
development of primary sexual characteristics GO:0045137 143 0.366
cellular amine metabolic process GO:0044106 44 0.359
rna splicing via transesterification reactions GO:0000375 43 0.358
positive regulation of histone modification GO:0031058 28 0.343
positive regulation of chromatin modification GO:1903310 28 0.341
negative regulation of mrna splicing via spliceosome GO:0048025 12 0.326
chromatin silencing GO:0006342 15 0.322
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.312
Human
viral life cycle GO:0019058 36 0.307
Human
ras protein signal transduction GO:0007265 77 0.305
ribonucleotide metabolic process GO:0009259 291 0.302
purine ribonucleoside catabolic process GO:0046130 205 0.297
regulation of nucleotide catabolic process GO:0030811 122 0.294
cellular ketone metabolic process GO:0042180 84 0.288
regulation of mitotic cell cycle phase transition GO:1901990 73 0.282
positive regulation of organelle organization GO:0010638 128 0.281
meiosis i GO:0007127 60 0.278
male gamete generation GO:0048232 285 0.273
nucleotide catabolic process GO:0009166 217 0.272
regulation of cell cycle phase transition GO:1901987 77 0.269
mitotic cell cycle process GO:1903047 159 0.268
rna processing GO:0006396 105 0.260
negative regulation of rna splicing GO:0033119 12 0.255
purine ribonucleoside metabolic process GO:0046128 241 0.251
histone h4 k20 trimethylation GO:0034773 2 0.251
positive regulation of cellular amine metabolic process GO:0033240 5 0.249
ribonucleoside triphosphate catabolic process GO:0009203 199 0.245
negative regulation of cellular protein metabolic process GO:0032269 247 0.245
purine nucleoside triphosphate metabolic process GO:0009144 226 0.244
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.241
nuclear division GO:0000280 158 0.240
regulation of ras protein signal transduction GO:0046578 114 0.239
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.232
peptidyl lysine modification GO:0018205 77 0.225
carbohydrate derivative catabolic process GO:1901136 231 0.220
purine containing compound catabolic process GO:0072523 213 0.220
ribonucleoside triphosphate metabolic process GO:0009199 220 0.220
regulation of rna splicing GO:0043484 37 0.217
positive regulation of chromosome organization GO:2001252 33 0.214
stem cell differentiation GO:0048863 268 0.213
regulation of cellular amine metabolic process GO:0033238 20 0.212
negative regulation of mrna metabolic process GO:1903312 13 0.211
positive regulation of histone h3 k9 methylation GO:0051574 4 0.209
negative regulation of kinase activity GO:0033673 81 0.208
negative regulation of protein metabolic process GO:0051248 282 0.204
negative regulation of transferase activity GO:0051348 85 0.200
ribose phosphate metabolic process GO:0019693 291 0.198
mrna transport GO:0051028 13 0.197
demethylation GO:0070988 23 0.196
dna conformation change GO:0071103 37 0.193
nucleoside triphosphate catabolic process GO:0009143 205 0.193
dna packaging GO:0006323 30 0.191
ribonucleoside catabolic process GO:0042454 206 0.190
purine nucleotide catabolic process GO:0006195 211 0.187
nucleotide metabolic process GO:0009117 332 0.185
transcription coupled nucleotide excision repair GO:0006283 2 0.177
regulation of nucleoside metabolic process GO:0009118 130 0.175
cellular amino acid metabolic process GO:0006520 103 0.174
regulation of protein localization GO:0032880 231 0.174
Human
regulation of nucleotide metabolic process GO:0006140 169 0.165
nucleoside phosphate metabolic process GO:0006753 338 0.160
purine ribonucleotide metabolic process GO:0009150 290 0.160
peptidyl lysine methylation GO:0018022 29 0.159
interspecies interaction between organisms GO:0044419 83 0.157
Human
telomere maintenance GO:0000723 19 0.155
nucleoside triphosphate metabolic process GO:0009141 230 0.154
gene silencing by rna GO:0031047 19 0.151
regulation of organelle organization GO:0033043 289 0.151
regulation of protein kinase activity GO:0045859 232 0.149
protein modification by small protein conjugation GO:0032446 187 0.149
Human Mouse
mrna metabolic process GO:0016071 84 0.147
organelle fission GO:0048285 170 0.143
regulation of chromatin organization GO:1902275 57 0.136
posttranscriptional regulation of gene expression GO:0010608 155 0.136
Mouse
purine nucleoside metabolic process GO:0042278 241 0.135
microtubule based process GO:0007017 236 0.133
antimicrobial peptide production GO:0002775 2 0.131
negative regulation of gene expression epigenetic GO:0045814 15 0.127
chromatin disassembly GO:0031498 1 0.126
positive regulation of chromosome segregation GO:0051984 4 0.125
spliceosomal complex assembly GO:0000245 6 0.124
peptidyl amino acid modification GO:0018193 336 0.122
microtubule cytoskeleton organization GO:0000226 157 0.121
regulation of mrna splicing via spliceosome GO:0048024 32 0.119
positive regulation of intracellular transport GO:0032388 70 0.118
Human
negative regulation of phosphorus metabolic process GO:0010563 184 0.118
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.118
Human
intracellular transport of virus GO:0075733 1 0.117
genitalia development GO:0048806 37 0.116
protein dna complex subunit organization GO:0071824 28 0.115
regulation of cell cycle g2 m phase transition GO:1902749 10 0.114
aromatic compound catabolic process GO:0019439 286 0.114
nucleobase containing compound transport GO:0015931 27 0.113
purine nucleotide metabolic process GO:0006163 302 0.109
chromatin remodeling GO:0006338 32 0.108
purine ribonucleotide catabolic process GO:0009154 208 0.107
cell cycle checkpoint GO:0000075 47 0.107
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.104
negative regulation of ras protein signal transduction GO:0046580 18 0.103
regulation of chromosome organization GO:0033044 83 0.103
dna dealkylation GO:0035510 11 0.101
nucleoside phosphate catabolic process GO:1901292 222 0.101
positive regulation of nucleotide catabolic process GO:0030813 88 0.099
gtp metabolic process GO:0046039 144 0.098
maintenance of apical basal cell polarity GO:0035090 3 0.097
regulation of dna damage checkpoint GO:2000001 3 0.096
maintenance of epithelial cell apical basal polarity GO:0045199 2 0.096
guanosine containing compound catabolic process GO:1901069 144 0.095
chemotaxis GO:0006935 247 0.093
Fly
protein modification by small protein removal GO:0070646 21 0.091
embryonic organ morphogenesis GO:0048562 276 0.089
negative regulation of protein modification process GO:0031400 163 0.089
gtp catabolic process GO:0006184 143 0.089
regulation of cell cycle process GO:0010564 160 0.089
negative regulation of phosphate metabolic process GO:0045936 184 0.088
organonitrogen compound catabolic process GO:1901565 264 0.088
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.086
positive regulation of gtpase activity GO:0043547 85 0.086
wnt signaling pathway GO:0016055 188 0.086
rna interference GO:0016246 2 0.085
protein targeting GO:0006605 143 0.083
Human
negative regulation of cellular component organization GO:0051129 194 0.083
organonitrogen compound biosynthetic process GO:1901566 192 0.081
organic cyclic compound catabolic process GO:1901361 295 0.079
dna methylation on cytosine GO:0032776 5 0.079
positive regulation of nucleotide metabolic process GO:0045981 114 0.078
heterocycle catabolic process GO:0046700 280 0.078
nucleocytoplasmic transport GO:0006913 139 0.076
Human
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.076
gonad development GO:0008406 141 0.074
regulation of establishment of protein localization GO:0070201 181 0.073
Human
germ cell development GO:0007281 185 0.072
regulation of purine nucleotide metabolic process GO:1900542 169 0.072
multicellular organism growth GO:0035264 161 0.072
negative regulation of molecular function GO:0044092 258 0.071
neuron projection guidance GO:0097485 141 0.067
Fly
cytoplasmic transport GO:0016482 234 0.067
Human
nucleoside catabolic process GO:0009164 206 0.067
regulation of cytoplasmic transport GO:1903649 112 0.067
Human
organophosphate catabolic process GO:0046434 232 0.066
regulation of purine nucleotide catabolic process GO:0033121 122 0.065
positive regulation of hydrolase activity GO:0051345 148 0.063
oocyte anterior posterior axis specification GO:0007314 2 0.062
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.061
regulation of mrna metabolic process GO:1903311 43 0.061
cellular response to cytokine stimulus GO:0071345 189 0.061
regulation of hydrolase activity GO:0051336 246 0.061
regulation of mrna processing GO:0050684 41 0.061
negative regulation of protein phosphorylation GO:0001933 126 0.060
negative regulation of cell proliferation GO:0008285 296 0.059
Mouse
protein localization to chromatin GO:0071168 3 0.059
posttranscriptional gene silencing GO:0016441 10 0.058
negative regulation of nervous system development GO:0051961 156 0.056
proteasomal protein catabolic process GO:0010498 98 0.056
glycosyl compound catabolic process GO:1901658 206 0.056
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.055
regulation of intracellular transport GO:0032386 159 0.054
Human
intracellular protein transport GO:0006886 204 0.054
Human
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.052
positive regulation of dna templated transcription elongation GO:0032786 2 0.052
negative regulation of viral process GO:0048525 23 0.052
Human
translation GO:0006412 93 0.051
regulation of gtp catabolic process GO:0033124 113 0.051
camera type eye development GO:0043010 266 0.051
positive regulation of gtp catabolic process GO:0033126 85 0.050
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.049
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.049
nucleotide excision repair GO:0006289 13 0.048
endocytosis GO:0006897 168 0.047
gland development GO:0048732 330 0.047
positive regulation of synaptic plasticity GO:0031915 4 0.046
regulation of kinase activity GO:0043549 249 0.046
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.046
anatomical structure homeostasis GO:0060249 145 0.045
negative regulation of multi organism process GO:0043901 68 0.045
Human
multi multicellular organism process GO:0044706 109 0.044
negative regulation of chromatin modification GO:1903309 19 0.044
positive regulation of retinoic acid receptor signaling pathway GO:0048386 3 0.044
receptor mediated endocytosis GO:0006898 51 0.044
nuclear export GO:0051168 34 0.043
developmental growth involved in morphogenesis GO:0060560 138 0.042
protein import into nucleus GO:0006606 95 0.042
Human
macromolecule catabolic process GO:0009057 281 0.042
Mouse
regulation of antimicrobial humoral response GO:0002759 3 0.042
nuclear transport GO:0051169 139 0.042
Human
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.042
Human
negative regulation of cell cycle process GO:0010948 69 0.041
protein localization to organelle GO:0033365 185 0.041
Human
cellular response to organic cyclic compound GO:0071407 87 0.041
Mouse
meiotic cell cycle GO:0051321 122 0.041
rna splicing GO:0008380 54 0.040
sensory organ morphogenesis GO:0090596 242 0.039
ribonucleoprotein complex subunit organization GO:0071826 28 0.039
regulation of cellular component biogenesis GO:0044087 181 0.038
locomotory behavior GO:0007626 195 0.038
spermatid differentiation GO:0048515 115 0.038
viral gene expression GO:0019080 3 0.037
heterochromatin assembly GO:0031507 2 0.037
focal adhesion assembly GO:0048041 19 0.037
regulation of cell motility GO:2000145 236 0.036
learning GO:0007612 98 0.036
negative regulation of phosphorylation GO:0042326 166 0.035
learning or memory GO:0007611 148 0.035
positive regulation of cellular component biogenesis GO:0044089 94 0.035
protein deubiquitination GO:0016579 19 0.034
positive regulation of growth GO:0045927 104 0.034
guanosine containing compound metabolic process GO:1901068 144 0.033
cognition GO:0050890 149 0.033
cellular homeostasis GO:0019725 240 0.033
histone h4 acetylation GO:0043967 10 0.033
regulation of cell cycle checkpoint GO:1901976 9 0.033
mesenchyme development GO:0060485 152 0.033
connective tissue development GO:0061448 179 0.033
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.033
establishment of protein localization to organelle GO:0072594 118 0.033
Human
primary mirna processing GO:0031053 1 0.032
protein ubiquitination GO:0016567 171 0.032
Human Mouse
rna transport GO:0050658 18 0.032
regulation of cellular catabolic process GO:0031329 242 0.032
regulation of protein serine threonine kinase activity GO:0071900 157 0.031
histone h4 k20 methylation GO:0034770 8 0.031
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.031
response to alcohol GO:0097305 48 0.031
Mouse
protein import GO:0017038 101 0.030
Human
cellular response to hormone stimulus GO:0032870 150 0.030
regulation of meiotic cell cycle GO:0051445 34 0.030
blastocyst growth GO:0001832 23 0.030
response to radiation GO:0009314 165 0.029
cellular protein catabolic process GO:0044257 155 0.028
nuclear import GO:0051170 95 0.028
Human
blastocyst hatching GO:0001835 4 0.028
regulation of binding GO:0051098 111 0.028
regulation of protein import into nucleus GO:0042306 52 0.028
Human
cellular response to peptide GO:1901653 92 0.027
protein complex disassembly GO:0043241 40 0.027
negative regulation of chromosome organization GO:2001251 30 0.027
negative regulation of mitotic cell cycle GO:0045930 58 0.027
establishment of rna localization GO:0051236 18 0.026
response to topologically incorrect protein GO:0035966 25 0.026
axonal fasciculation GO:0007413 15 0.026
recombinational repair GO:0000725 21 0.026
rhythmic process GO:0048511 174 0.025
regulation of multi organism process GO:0043900 111 0.025
Human
regulation of rna export from nucleus GO:0046831 4 0.025
histone h2a ubiquitination GO:0033522 3 0.025
rna export from nucleus GO:0006405 15 0.025
positive regulation of rna splicing GO:0033120 12 0.024
entry into host GO:0044409 15 0.024
response to light stimulus GO:0009416 135 0.024
positive regulation of cell cycle phase transition GO:1901989 17 0.024
single organism nuclear import GO:1902593 95 0.024
Human
peptidyl lysine dimethylation GO:0018027 6 0.023
regulation of mitochondrion organization GO:0010821 27 0.023
transcription elongation from rna polymerase ii promoter GO:0006368 9 0.023
regulation of mitotic cell cycle GO:0007346 126 0.023
dna templated transcription elongation GO:0006354 13 0.023
divalent inorganic cation homeostasis GO:0072507 138 0.023
Mouse
alternative mrna splicing via spliceosome GO:0000380 12 0.023
histone h3 k4 methylation GO:0051568 23 0.023
dendrite development GO:0016358 115 0.023
Fly
meiotic nuclear division GO:0007126 115 0.022
regulation of peptidyl lysine acetylation GO:2000756 22 0.022
base excision repair GO:0006284 9 0.022
spermatid development GO:0007286 108 0.022
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.022
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.022
regulation of antimicrobial peptide production GO:0002784 1 0.021
meiotic cell cycle process GO:1903046 77 0.021
ameboidal type cell migration GO:0001667 128 0.021
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.021
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.021
regulation of chromatin binding GO:0035561 7 0.021
positive regulation of nucleoside metabolic process GO:0045979 91 0.021
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 18 0.021
atp metabolic process GO:0046034 75 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
primary neural tube formation GO:0014020 95 0.020
motor neuron migration GO:0097475 4 0.020
regulation of protein transport GO:0051223 163 0.020
Human
cytoplasmic translational initiation GO:0002183 3 0.020
peptidyl lysine trimethylation GO:0018023 12 0.020
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.020
multicellular organismal homeostasis GO:0048871 164 0.020
stem cell development GO:0048864 219 0.019
positive regulation of cell death GO:0010942 224 0.019
defense response to bacterium GO:0042742 119 0.019
carbohydrate biosynthetic process GO:0016051 74 0.019
trna wobble uridine modification GO:0002098 2 0.019
viral transcription GO:0019083 3 0.019
skeletal system development GO:0001501 356 0.019
metal ion homeostasis GO:0055065 189 0.019
Mouse
regulation of g2 m transition of mitotic cell cycle GO:0010389 10 0.019
epithelial tube morphogenesis GO:0060562 303 0.019
segmentation GO:0035282 93 0.019
dna recombination GO:0006310 92 0.019
calcium ion homeostasis GO:0055074 127 0.019
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.018
viral process GO:0016032 41 0.018
Human
female gamete generation GO:0007292 74 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
spindle organization GO:0007051 28 0.018
mrna processing GO:0006397 63 0.018
molting cycle GO:0042303 90 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.018
negative regulation of peroxisome proliferator activated receptor signaling pathway GO:0035359 3 0.018
multicellular organismal aging GO:0010259 24 0.017
localization within membrane GO:0051668 4 0.017
pole plasm assembly GO:0007315 2 0.017
response to acid chemical GO:0001101 111 0.017
stem cell fate specification GO:0048866 3 0.017
body morphogenesis GO:0010171 45 0.017
mitotic g2 dna damage checkpoint GO:0007095 8 0.017
cellular protein complex assembly GO:0043623 116 0.017
fat cell differentiation GO:0045444 160 0.017
heart process GO:0003015 94 0.017
response to transforming growth factor beta GO:0071559 88 0.016
epithelial cell proliferation GO:0050673 174 0.016
negative regulation of cell cycle phase transition GO:1901988 48 0.016
regulation of mammary gland epithelial cell proliferation GO:0033599 12 0.016
regulation of secretion by cell GO:1903530 249 0.016
monoubiquitinated histone deubiquitination GO:0035521 1 0.016
negative regulation of histone h3 k9 methylation GO:0051573 4 0.016
mesenchymal cell development GO:0014031 93 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
histone h3 k14 acetylation GO:0044154 3 0.016
negative regulation of nucleotide catabolic process GO:0030812 9 0.016
establishment of planar polarity GO:0001736 28 0.016
negative regulation of organelle organization GO:0010639 90 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
innate immune response GO:0045087 157 0.015
Human
ribonucleoside monophosphate catabolic process GO:0009158 57 0.015
internal protein amino acid acetylation GO:0006475 42 0.015
peptide secretion GO:0002790 114 0.015
regulation of transposition GO:0010528 2 0.015
peptidyl lysine monomethylation GO:0018026 1 0.015
adult behavior GO:0030534 135 0.015
mitotic nuclear division GO:0007067 48 0.015
maintenance of location GO:0051235 89 0.015
immune effector process GO:0002252 321 0.015
purine nucleoside monophosphate catabolic process GO:0009128 58 0.015
nitrogen compound transport GO:0071705 271 0.015
purine containing compound biosynthetic process GO:0072522 70 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.014
regulation of peptide secretion GO:0002791 77 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
protein localization to nucleus GO:0034504 121 0.014
Human
telencephalon development GO:0021537 186 0.014
regulation of fat cell differentiation GO:0045598 81 0.014
regulation of histone h3 k4 methylation GO:0051569 12 0.014
heterochromatin organization GO:0070828 4 0.014
divalent metal ion transport GO:0070838 172 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
cell fate determination involved in pattern specification GO:0060582 1 0.014
positive regulation of binding GO:0051099 49 0.014
neuron migration GO:0001764 122 0.014
regulation of chromatin silencing GO:0031935 2 0.014
organism emergence from protective structure GO:0071684 4 0.014
regulation of mapk cascade GO:0043408 248 0.014
regulation of viral transcription GO:0046782 3 0.013
transmembrane transport GO:0055085 412 0.013
regulation of hormone levels GO:0010817 211 0.013
hatching GO:0035188 4 0.013
receptor biosynthetic process GO:0032800 3 0.013
regulation of intracellular protein transport GO:0033157 82 0.013
Human
negative regulation of viral transcription GO:0032897 3 0.013
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter GO:0072364 7 0.013
cellular response to interleukin 4 GO:0071353 21 0.013
pharynx development GO:0060465 1 0.013
response to organic cyclic compound GO:0014070 198 0.013
Mouse
establishment or maintenance of neuroblast polarity GO:0045196 1 0.013
cell junction assembly GO:0034329 52 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
antimicrobial peptide biosynthetic process GO:0002777 2 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
gliogenesis GO:0042063 141 0.013
negative regulation of cell adhesion GO:0007162 45 0.013
response to temperature stimulus GO:0009266 55 0.013
epidermis development GO:0008544 187 0.013
negative regulation of proteolysis GO:0045861 74 0.013
embryonic axis specification GO:0000578 30 0.013
mitotic cell cycle checkpoint GO:0007093 31 0.013
organ growth GO:0035265 117 0.012
mammary gland epithelium development GO:0061180 65 0.012
response to interleukin 4 GO:0070670 23 0.012
hair follicle placode formation GO:0060789 5 0.012
peptide hormone secretion GO:0030072 109 0.012
mesenchymal cell differentiation GO:0048762 107 0.012
response to oxidative stress GO:0006979 123 0.012
positive regulation of immune effector process GO:0002699 107 0.012
positive regulation of dna templated transcription initiation GO:2000144 5 0.012
cell growth GO:0016049 130 0.012
leukocyte differentiation GO:0002521 342 0.012
protein processing GO:0016485 163 0.012
negative regulation of secretion by cell GO:1903531 54 0.012
hepaticobiliary system development GO:0061008 67 0.012
negative regulation of histone modification GO:0031057 18 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
inner cell mass cell proliferation GO:0001833 15 0.011
oogenesis GO:0048477 56 0.011
positive regulation of histone h3 k4 methylation GO:0051571 5 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
positive regulation of gluconeogenesis by positive regulation of transcription from rna polymerase ii promoter GO:0035948 5 0.011
dna integrity checkpoint GO:0031570 28 0.011
circadian regulation of gene expression GO:0032922 48 0.011
response to amino acid GO:0043200 37 0.011
intrahepatic bile duct development GO:0035622 2 0.011
histone acetylation GO:0016573 41 0.011
calcium ion transport GO:0006816 159 0.011
homeostasis of number of cells GO:0048872 210 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
cell recognition GO:0008037 83 0.011
s adenosylhomocysteine metabolic process GO:0046498 1 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
multi organism reproductive behavior GO:0044705 29 0.011
regulation of interleukin 2 secretion GO:1900040 6 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
transmission of nerve impulse GO:0019226 76 0.011
dna unwinding involved in dna replication GO:0006268 5 0.011
carbohydrate homeostasis GO:0033500 128 0.011
jak stat cascade GO:0007259 42 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.010
atp catabolic process GO:0006200 55 0.010
response to nerve growth factor GO:1990089 3 0.010
embryonic placenta development GO:0001892 98 0.010
response to peptide hormone GO:0043434 127 0.010
response to organonitrogen compound GO:0010243 246 0.010

Trim28 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.155
nervous system disease DOID:863 0 0.155
retinal disease DOID:5679 0 0.132
sensory system disease DOID:0050155 0 0.132
eye and adnexa disease DOID:1492 0 0.132
eye disease DOID:5614 0 0.132
neuropathy DOID:870 0 0.063
retinal degeneration DOID:8466 0 0.036
retinitis pigmentosa DOID:10584 0 0.036
disease of cellular proliferation DOID:14566 0 0.034
central nervous system disease DOID:331 0 0.022
neurodegenerative disease DOID:1289 0 0.018
hereditary sensory neuropathy DOID:0050548 0 0.012
peripheral neuropathy DOID:0060053 0 0.012
neuromuscular disease DOID:440 0 0.011