Mus musculus

50 known processes

Ttc3

tetratricopeptide repeat domain 3

(Aliases: TPRD,KIAA4119,mKIAA4119,D16Ium21e,AA409221,D16Ium21,2610202A04Rik)

Ttc3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 5 0.210
axon guidance GO:0007411 141 0.203
posttranscriptional regulation of gene expression GO:0010608 155 0.188
chromatin modification GO:0016568 187 0.148
peptidyl amino acid modification GO:0018193 336 0.145
regulation of cellular component biogenesis GO:0044087 181 0.142
chromatin organization GO:0006325 206 0.128
dna metabolic process GO:0006259 303 0.119
cellular ketone metabolic process GO:0042180 84 0.106
ribonucleoside catabolic process GO:0042454 206 0.104
chemotaxis GO:0006935 247 0.103
dna recombination GO:0006310 92 0.097
axon cargo transport GO:0008088 33 0.096
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.096
regulation of cellular amine metabolic process GO:0033238 20 0.092
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.090
microtubule based process GO:0007017 236 0.086
histone modification GO:0016570 159 0.085
cellular amine metabolic process GO:0044106 44 0.084
central nervous system neuron axonogenesis GO:0021955 28 0.084
response to molecule of bacterial origin GO:0002237 143 0.082
covalent chromatin modification GO:0016569 163 0.078
spermatogenesis GO:0007283 284 0.078
dendrite development GO:0016358 115 0.078
male gamete generation GO:0048232 285 0.075
amine metabolic process GO:0009308 45 0.074
regulation of cell motility GO:2000145 236 0.074
neuron projection guidance GO:0097485 141 0.074
negative regulation of protein metabolic process GO:0051248 282 0.072
learning or memory GO:0007611 148 0.071
regulation of cellular ketone metabolic process GO:0010565 66 0.071
purine containing compound metabolic process GO:0072521 311 0.070
membrane organization GO:0061024 245 0.070
nucleoside monophosphate metabolic process GO:0009123 85 0.068
peptidyl lysine modification GO:0018205 77 0.067
ribonucleoside triphosphate metabolic process GO:0009199 220 0.064
positive regulation of nervous system development GO:0051962 221 0.064
cytoskeleton dependent intracellular transport GO:0030705 50 0.063
positive regulation of neuron differentiation GO:0045666 141 0.062
heterocycle catabolic process GO:0046700 280 0.062
negative regulation of phosphorus metabolic process GO:0010563 184 0.062
negative regulation of phosphate metabolic process GO:0045936 184 0.061
negative regulation of cellular protein metabolic process GO:0032269 247 0.061
nucleobase containing small molecule metabolic process GO:0055086 352 0.060
glycosyl compound catabolic process GO:1901658 206 0.059
cellular nitrogen compound catabolic process GO:0044270 280 0.057
microtubule cytoskeleton organization GO:0000226 157 0.056
translation GO:0006412 93 0.054
peptidyl serine modification GO:0018209 83 0.054
central nervous system projection neuron axonogenesis GO:0021952 21 0.054
leukocyte differentiation GO:0002521 342 0.053
ribonucleoside monophosphate metabolic process GO:0009161 80 0.053
regulation of peptidyl serine phosphorylation GO:0033135 39 0.053
histone acetylation GO:0016573 41 0.052
positive regulation of cellular amine metabolic process GO:0033240 5 0.051
regulation of chromosome organization GO:0033044 83 0.051
apoptotic signaling pathway GO:0097190 306 0.051
negative regulation of synapse assembly GO:0051964 3 0.050
negative regulation of cell proliferation GO:0008285 296 0.049
purine nucleoside monophosphate catabolic process GO:0009128 58 0.049
macromolecule methylation GO:0043414 120 0.049
germ cell development GO:0007281 185 0.048
response to organonitrogen compound GO:0010243 246 0.048
small gtpase mediated signal transduction GO:0007264 97 0.048
atp metabolic process GO:0046034 75 0.047
protein modification by small protein conjugation GO:0032446 187 0.047
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.046
formation of primary germ layer GO:0001704 77 0.045
dna repair GO:0006281 107 0.044
regulation of mrna metabolic process GO:1903311 43 0.044
purine ribonucleoside metabolic process GO:0046128 241 0.044
mesoderm morphogenesis GO:0048332 64 0.043
cell type specific apoptotic process GO:0097285 268 0.043
cellular response to lipopolysaccharide GO:0071222 77 0.042
negative regulation of intracellular signal transduction GO:1902532 167 0.042
intracellular protein transport GO:0006886 204 0.041
ribonucleoside monophosphate catabolic process GO:0009158 57 0.041
protein modification by small protein conjugation or removal GO:0070647 207 0.041
Human
ribonucleoside metabolic process GO:0009119 245 0.040
blood vessel morphogenesis GO:0048514 285 0.040
positive regulation of protein modification process GO:0031401 299 0.040
cellular amino acid metabolic process GO:0006520 103 0.040
microtubule based transport GO:0010970 50 0.040
purine nucleoside triphosphate metabolic process GO:0009144 226 0.040
epithelial cell proliferation GO:0050673 174 0.040
regulation of cell projection organization GO:0031344 206 0.039
cognition GO:0050890 149 0.039
camera type eye development GO:0043010 266 0.039
regulation of cellular component size GO:0032535 121 0.039
somatic diversification of immunoglobulins GO:0016445 43 0.039
v d j recombination GO:0033151 14 0.039
organic cyclic compound catabolic process GO:1901361 295 0.038
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.038
organelle localization GO:0051640 179 0.038
macromolecule catabolic process GO:0009057 281 0.038
Human
nucleoside triphosphate catabolic process GO:0009143 205 0.037
digestive system development GO:0055123 200 0.036
purine nucleotide metabolic process GO:0006163 302 0.036
nucleoside phosphate catabolic process GO:1901292 222 0.036
regulation of leukocyte proliferation GO:0070663 121 0.036
digestive tract development GO:0048565 190 0.036
peptidyl lysine acetylation GO:0018394 45 0.035
posttranscriptional gene silencing by rna GO:0035194 10 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
body morphogenesis GO:0010171 45 0.035
regulation of mapk cascade GO:0043408 248 0.035
synapse organization GO:0050808 125 0.035
regionalization GO:0003002 337 0.034
regulation of cellular catabolic process GO:0031329 242 0.034
aromatic compound catabolic process GO:0019439 286 0.033
regulation of apoptotic signaling pathway GO:2001233 197 0.033
purine ribonucleotide catabolic process GO:0009154 208 0.033
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.032
nucleotide catabolic process GO:0009166 217 0.032
regulation of cytoskeleton organization GO:0051493 122 0.032
cellular response to lipid GO:0071396 145 0.032
ribonucleoside triphosphate catabolic process GO:0009203 199 0.032
nucleoside metabolic process GO:0009116 246 0.032
purine ribonucleotide metabolic process GO:0009150 290 0.031
regulation of mrna processing GO:0050684 41 0.030
carbohydrate derivative catabolic process GO:1901136 231 0.030
positive regulation of cell activation GO:0050867 158 0.030
nucleoside monophosphate catabolic process GO:0009125 59 0.030
trna wobble uridine modification GO:0002098 2 0.028
midgut development GO:0007494 4 0.028
cell adhesion GO:0007155 329 0.028
protein polymerization GO:0051258 57 0.028
positive regulation of apoptotic process GO:0043065 217 0.028
response to lipopolysaccharide GO:0032496 128 0.027
protein acylation GO:0043543 64 0.027
regulation of wnt signaling pathway GO:0030111 123 0.027
regulation of organelle organization GO:0033043 289 0.027
ras protein signal transduction GO:0007265 77 0.027
ribonucleotide catabolic process GO:0009261 208 0.027
positive regulation of protein phosphorylation GO:0001934 242 0.027
peptidyl serine phosphorylation GO:0018105 74 0.027
regulation of anatomical structure size GO:0090066 178 0.027
cellular component assembly involved in morphogenesis GO:0010927 139 0.026
positive regulation of programmed cell death GO:0043068 218 0.026
negative regulation of molecular function GO:0044092 258 0.026
dna methylation GO:0006306 43 0.026
negative regulation of phosphorylation GO:0042326 166 0.026
purine containing compound catabolic process GO:0072523 213 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
genitalia development GO:0048806 37 0.026
negative regulation of lymphocyte activation GO:0051250 91 0.025
trna wobble base modification GO:0002097 2 0.025
striated muscle tissue development GO:0014706 293 0.025
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.025
protein methylation GO:0006479 81 0.025
synapse assembly GO:0007416 56 0.025
histone methylation GO:0016571 71 0.024
endocytosis GO:0006897 168 0.024
regulation of muscle tissue development GO:1901861 97 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
negative regulation of wnt signaling pathway GO:0030178 73 0.024
stem cell maintenance GO:0019827 130 0.024
mitochondrion organization GO:0007005 134 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
protein localization to organelle GO:0033365 185 0.024
purine nucleoside monophosphate metabolic process GO:0009126 81 0.023
myeloid cell homeostasis GO:0002262 114 0.023
peptidyl threonine modification GO:0018210 31 0.023
pole plasm assembly GO:0007315 2 0.023
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.023
establishment of protein localization to endoplasmic reticulum GO:0072599 2 0.023
skeletal muscle organ development GO:0060538 163 0.023
peptidyl lysine methylation GO:0018022 29 0.023
cellular response to dna damage stimulus GO:0006974 207 0.023
protein ubiquitination GO:0016567 171 0.023
Human
stem cell differentiation GO:0048863 268 0.023
forebrain development GO:0030900 302 0.023
negative regulation of multi organism process GO:0043901 68 0.023
renal tubule morphogenesis GO:0061333 72 0.023
regulation of actin filament polymerization GO:0030833 38 0.022
internal peptidyl lysine acetylation GO:0018393 42 0.022
tetrapyrrole metabolic process GO:0033013 22 0.022
negative regulation of protein modification process GO:0031400 163 0.022
ventricular cardiac myofibril assembly GO:0055005 3 0.022
negative regulation of nervous system development GO:0051961 156 0.022
regulation of mrna splicing via spliceosome GO:0048024 32 0.022
cell fate commitment GO:0045165 210 0.022
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.022
urogenital system development GO:0001655 261 0.022
negative regulation of apoptotic signaling pathway GO:2001234 104 0.022
myeloid cell differentiation GO:0030099 233 0.022
nucleoside catabolic process GO:0009164 206 0.022
cellular alcohol metabolic process GO:0044107 3 0.021
regulation of neuron projection development GO:0010975 169 0.021
muscle tissue development GO:0060537 308 0.021
positive regulation of cell development GO:0010720 237 0.021
regulation of cell migration GO:0030334 219 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
organophosphate catabolic process GO:0046434 232 0.020
methylation GO:0032259 134 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
cellular response to biotic stimulus GO:0071216 92 0.020
positive regulation of mapk cascade GO:0043410 170 0.020
microtubule based movement GO:0007018 84 0.020
skeletal system development GO:0001501 356 0.020
regulation of circadian rhythm GO:0042752 58 0.020
kidney development GO:0001822 213 0.020
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.020
gonad morphogenesis GO:0035262 1 0.020
immune effector process GO:0002252 321 0.020
regulation of cell adhesion GO:0030155 154 0.019
double strand break repair GO:0006302 48 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
organelle assembly GO:0070925 177 0.019
adult behavior GO:0030534 135 0.019
dendritic spine organization GO:0097061 26 0.019
meiotic nuclear division GO:0007126 115 0.019
retinal ganglion cell axon guidance GO:0031290 18 0.019
neural tube development GO:0021915 160 0.019
posttranslational protein targeting to membrane GO:0006620 2 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
mesoderm formation GO:0001707 62 0.019
regulation of translation GO:0006417 71 0.019
synaptic transmission GO:0007268 329 0.019
porphyrin containing compound metabolic process GO:0006778 22 0.019
cellular response to organic cyclic compound GO:0071407 87 0.019
skeletal muscle cell differentiation GO:0035914 66 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
transmembrane transport GO:0055085 412 0.019
neuron migration GO:0001764 122 0.019
regulation of ras protein signal transduction GO:0046578 114 0.019
intracellular receptor signaling pathway GO:0030522 74 0.019
oxidation reduction process GO:0055114 342 0.019
regulation of protein complex assembly GO:0043254 83 0.019
peripheral nervous system neuron axonogenesis GO:0048936 3 0.018
striated muscle cell proliferation GO:0014855 39 0.018
production of molecular mediator of immune response GO:0002440 103 0.018
regulation of actin filament based process GO:0032970 99 0.018
actin polymerization or depolymerization GO:0008154 54 0.018
protein alkylation GO:0008213 81 0.018
cytoplasmic transport GO:0016482 234 0.018
muscle cell differentiation GO:0042692 261 0.018
regulation of neuron apoptotic process GO:0043523 122 0.018
development of primary sexual characteristics GO:0045137 143 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
Human
somatic cell dna recombination GO:0016444 51 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
t cell activation GO:0042110 289 0.017
mesoderm development GO:0007498 100 0.017
photoreceptor cell development GO:0042461 40 0.017
intracellular mrna localization GO:0008298 4 0.017
internal protein amino acid acetylation GO:0006475 42 0.017
regulation of actin cytoskeleton organization GO:0032956 84 0.017
gonad development GO:0008406 141 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
rna interference GO:0016246 2 0.016
central nervous system neuron differentiation GO:0021953 162 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
muscle adaptation GO:0043500 39 0.016
gastrulation GO:0007369 116 0.016
cell division GO:0051301 120 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
nephron epithelium development GO:0072009 92 0.016
positive regulation of cellular component biogenesis GO:0044089 94 0.016
cellular response to molecule of bacterial origin GO:0071219 83 0.016
rna splicing GO:0008380 54 0.015
terminal button organization GO:0072553 3 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
positive regulation of hh target transcription factor activity GO:0007228 3 0.015
i kappab kinase nf kappab signaling GO:0007249 85 0.015
regulation of neuron death GO:1901214 134 0.015
positive regulation of organelle organization GO:0010638 128 0.015
oocyte anterior posterior axis specification GO:0007314 2 0.015
circadian rhythm GO:0007623 114 0.015
histone h3 k4 trimethylation GO:0080182 5 0.015
limb morphogenesis GO:0035108 149 0.015
rhythmic process GO:0048511 174 0.015
endomembrane system organization GO:0010256 147 0.015
cell growth GO:0016049 130 0.015
atp catabolic process GO:0006200 55 0.015
neural tube patterning GO:0021532 43 0.014
t cell proliferation GO:0042098 120 0.014
dna packaging GO:0006323 30 0.014
anterior head development GO:0097065 2 0.014
endodermal cell fate specification GO:0001714 4 0.014
dna alkylation GO:0006305 43 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
striated muscle cell development GO:0055002 125 0.014
regulation of cell activation GO:0050865 289 0.014
fat cell differentiation GO:0045444 160 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
positive regulation of intracellular transport GO:0032388 70 0.014
positive regulation of dna templated transcription elongation GO:0032786 2 0.014
negative regulation of translation GO:0017148 22 0.014
response to parathyroid hormone GO:0071107 3 0.013
response to organic cyclic compound GO:0014070 198 0.013
positive regulation of cell death GO:0010942 224 0.013
cilium morphogenesis GO:0060271 102 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
mitotic cell cycle process GO:1903047 159 0.013
regulation of actin filament length GO:0030832 45 0.013
negative regulation of defense response GO:0031348 77 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.013
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.013
negative regulation of cell development GO:0010721 169 0.013
regulation of skeletal muscle adaptation GO:0014733 12 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
cellular protein complex assembly GO:0043623 116 0.013
regulation of histone modification GO:0031056 56 0.013
t cell differentiation GO:0030217 174 0.013
regulation of sarcomere organization GO:0060297 4 0.013
response to drug GO:0042493 75 0.013
protein targeting to membrane GO:0006612 20 0.013
cellular response to parathyroid hormone stimulus GO:0071374 2 0.013
axonogenesis GO:0007409 274 0.013
regulation of dna recombination GO:0000018 34 0.013
positive regulation of wnt signaling pathway GO:0030177 45 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
circadian behavior GO:0048512 13 0.013
axon target recognition GO:0007412 4 0.013
cofactor metabolic process GO:0051186 80 0.013
nuclear transcribed mrna catabolic process GO:0000956 16 0.013
stem cell fate specification GO:0048866 3 0.012
rac protein signal transduction GO:0016601 13 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
bmp signaling pathway GO:0030509 93 0.012
negative regulation of cell activation GO:0050866 111 0.012
mapk cascade GO:0000165 281 0.012
regulation of membrane potential GO:0042391 192 0.012
neuroblast differentiation GO:0014016 2 0.012
female gamete generation GO:0007292 74 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
energy derivation by oxidation of organic compounds GO:0015980 77 0.012
neuron projection extension GO:1990138 64 0.012
smoothened signaling pathway GO:0007224 105 0.012
response to transforming growth factor beta GO:0071559 88 0.012
determination of left right symmetry GO:0007368 80 0.012
stem cell development GO:0048864 219 0.012
mitochondrion distribution GO:0048311 4 0.012
negative regulation of cell motility GO:2000146 61 0.012
developmental maturation GO:0021700 193 0.012
muscle fiber development GO:0048747 76 0.012
response to peptide GO:1901652 136 0.012
homeostasis of number of cells GO:0048872 210 0.012
palate development GO:0060021 76 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
humoral immune response GO:0006959 57 0.012
endoderm development GO:0007492 45 0.012
regulation of anterior head development GO:2000742 2 0.011
regulation of multi organism process GO:0043900 111 0.011
lymphocyte homeostasis GO:0002260 64 0.011
multicellular organism growth GO:0035264 161 0.011
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.011
olfactory learning GO:0008355 2 0.011
regulation of protein processing GO:0070613 96 0.011
kidney epithelium development GO:0072073 121 0.011
cerebral cortex radially oriented cell migration GO:0021799 31 0.011
negative regulation of mapk cascade GO:0043409 65 0.011
positive regulation of transferase activity GO:0051347 167 0.011
protein catabolic process GO:0030163 221 0.011
Human
leukocyte mediated immunity GO:0002443 174 0.011
somatic diversification of immune receptors GO:0002200 53 0.011
regulation of microtubule cytoskeleton organization GO:0070507 37 0.011
immunoglobulin production GO:0002377 73 0.011
cellular ion homeostasis GO:0006873 165 0.011
wnt signaling pathway GO:0016055 188 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
regulation of protein localization GO:0032880 231 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
regulation of dna dependent dna replication GO:0090329 8 0.011
nucleoside phosphate metabolic process GO:0006753 338 0.011
positive regulation of chromosome organization GO:2001252 33 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.011
inositol lipid mediated signaling GO:0048017 41 0.011
establishment of organelle localization GO:0051656 122 0.011
golgi vesicle transport GO:0048193 30 0.011
nitrogen compound transport GO:0071705 271 0.010
response to nutrient levels GO:0031667 109 0.010
intraciliary transport GO:0042073 9 0.010
epidermal growth factor receptor signaling pathway GO:0007173 28 0.010
nuclear transport GO:0051169 139 0.010
dna conformation change GO:0071103 37 0.010
neuron death GO:0070997 154 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.010
response to acid chemical GO:0001101 111 0.010
adaptive immune response GO:0002250 155 0.010
nucleotide metabolic process GO:0009117 332 0.010
purine nucleotide catabolic process GO:0006195 211 0.010

Ttc3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.055
nervous system disease DOID:863 0 0.055
central nervous system disease DOID:331 0 0.021
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013