Mus musculus

21 known processes

Tuba1b

tubulin, alpha 1B

(Aliases: MGC117866,MGC118411,MGC102558,Tuba2)

Tuba1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
microtubule cytoskeleton organization GO:0000226 157 0.341
cellular response to interleukin 4 GO:0071353 21 0.273
regulation of protein transport GO:0051223 163 0.230
dna repair GO:0006281 107 0.206
intracellular protein transport GO:0006886 204 0.168
negative regulation of cell size GO:0045792 3 0.147
camera type eye development GO:0043010 266 0.144
protein targeting GO:0006605 143 0.144
regulation of intracellular protein transport GO:0033157 82 0.135
protein localization to nucleus GO:0034504 121 0.135
ion transmembrane transport GO:0034220 361 0.121
regulation of intracellular transport GO:0032386 159 0.119
positive regulation of protein modification process GO:0031401 299 0.119
organelle assembly GO:0070925 177 0.117
transmembrane transport GO:0055085 412 0.115
sensory organ morphogenesis GO:0090596 242 0.108
single organism nuclear import GO:1902593 95 0.107
nucleobase containing small molecule metabolic process GO:0055086 352 0.106
cellular response to cytokine stimulus GO:0071345 189 0.101
regulation of hydrolase activity GO:0051336 246 0.098
protein modification by small protein conjugation or removal GO:0070647 207 0.098
protein secretion GO:0009306 111 0.089
purine ribonucleoside metabolic process GO:0046128 241 0.083
regulation of protein localization GO:0032880 231 0.083
regulation of secretion by cell GO:1903530 249 0.078
cation transport GO:0006812 399 0.078
gene silencing GO:0016458 38 0.073
response to amino acid GO:0043200 37 0.068
positive regulation of protein transport GO:0051222 93 0.065
regulation of body fluid levels GO:0050878 162 0.059
cardiac muscle cell development GO:0055013 39 0.058
hexose catabolic process GO:0019320 3 0.058
lipid particle organization GO:0034389 7 0.057
regulation of establishment of protein localization GO:0070201 181 0.057
regulation of ion transmembrane transport GO:0034765 119 0.056
organophosphate biosynthetic process GO:0090407 122 0.055
embryonic organ morphogenesis GO:0048562 276 0.053
spindle assembly GO:0051225 13 0.051
chromatin organization GO:0006325 206 0.050
retina homeostasis GO:0001895 23 0.048
chromatin modification GO:0016568 187 0.047
wound healing GO:0042060 157 0.047
nadph regeneration GO:0006740 2 0.046
oxidation reduction process GO:0055114 342 0.045
ear development GO:0043583 200 0.044
transcription coupled nucleotide excision repair GO:0006283 2 0.043
actin filament based movement GO:0030048 23 0.043
positive regulation of viral genome replication GO:0045070 2 0.043
regulation of cellular amino acid metabolic process GO:0006521 5 0.042
cellular nitrogen compound catabolic process GO:0044270 280 0.041
protein localization to organelle GO:0033365 185 0.041
regulation of protein secretion GO:0050708 82 0.041
skeletal muscle fiber development GO:0048741 58 0.041
regulation of transporter activity GO:0032409 57 0.040
protein import GO:0017038 101 0.039
protein ubiquitination GO:0016567 171 0.039
peptidyl amino acid modification GO:0018193 336 0.038
telencephalon development GO:0021537 186 0.038
blood circulation GO:0008015 195 0.038
cofactor metabolic process GO:0051186 80 0.036
cation transmembrane transport GO:0098655 266 0.036
protein depolymerization GO:0051261 34 0.036
inorganic ion transmembrane transport GO:0098660 234 0.036
protein catabolic process GO:0030163 221 0.036
nucleocytoplasmic transport GO:0006913 139 0.035
cranial nerve formation GO:0021603 4 0.035
cellular response to dna damage stimulus GO:0006974 207 0.035
posttranscriptional gene silencing GO:0016441 10 0.034
blood coagulation GO:0007596 76 0.034
positive regulation of protein phosphorylation GO:0001934 242 0.033
nucleotide metabolic process GO:0009117 332 0.033
rna interference GO:0016246 2 0.032
cytoplasmic transport GO:0016482 234 0.032
chronological cell aging GO:0001300 1 0.032
spindle organization GO:0007051 28 0.032
regulation of secretion GO:0051046 274 0.032
receptor mediated endocytosis GO:0006898 51 0.032
substantia nigra development GO:0021762 2 0.031
cellular component assembly involved in morphogenesis GO:0010927 139 0.031
nucleotide biosynthetic process GO:0009165 78 0.029
protein modification by small protein conjugation GO:0032446 187 0.029
response to oxidative stress GO:0006979 123 0.029
muscle system process GO:0003012 141 0.029
viral process GO:0016032 41 0.029
regulation of cytoplasmic transport GO:1903649 112 0.029
gene silencing by rna GO:0031047 19 0.028
negative regulation of purine nucleotide catabolic process GO:0033122 9 0.028
regulation of nucleotide catabolic process GO:0030811 122 0.028
glucose catabolic process GO:0006007 3 0.027
organophosphate catabolic process GO:0046434 232 0.027
thermosensory behavior GO:0040040 1 0.027
circulatory system process GO:0003013 197 0.027
response to interleukin 4 GO:0070670 23 0.027
multicellular organismal homeostasis GO:0048871 164 0.027
cytoskeleton dependent intracellular transport GO:0030705 50 0.027
atp catabolic process GO:0006200 55 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
engulfment of apoptotic cell GO:0043652 3 0.027
regulation of cellular ketone metabolic process GO:0010565 66 0.026
recombinational repair GO:0000725 21 0.026
mesenchyme development GO:0060485 152 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
vasoconstriction GO:0042310 27 0.026
dna metabolic process GO:0006259 303 0.026
microtubule based transport GO:0010970 50 0.026
anatomical structure homeostasis GO:0060249 145 0.025
cellular ketone metabolic process GO:0042180 84 0.025
purine nucleotide metabolic process GO:0006163 302 0.025
sequestering of calcium ion GO:0051208 18 0.025
embryonic epithelial tube formation GO:0001838 130 0.025
meiotic cell cycle GO:0051321 122 0.025
dna hypermethylation GO:0044026 3 0.025
regulation of nucleocytoplasmic transport GO:0046822 73 0.024
actin mediated cell contraction GO:0070252 15 0.024
heart morphogenesis GO:0003007 178 0.024
cellular modified amino acid metabolic process GO:0006575 63 0.024
actin filament organization GO:0007015 113 0.024
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.024
divalent metal ion transport GO:0070838 172 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
smooth muscle contraction GO:0006939 44 0.024
nuclear import GO:0051170 95 0.024
intermediate filament bundle assembly GO:0045110 3 0.024
epidermis development GO:0008544 187 0.024
internal protein amino acid acetylation GO:0006475 42 0.023
stem cell proliferation GO:0072089 117 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
positive regulation of intracellular protein transport GO:0090316 42 0.023
urogenital system development GO:0001655 261 0.023
heterocycle catabolic process GO:0046700 280 0.023
histone acetylation GO:0016573 41 0.023
cellular response to oxidative stress GO:0034599 76 0.023
cardiac muscle contraction GO:0060048 32 0.022
small gtpase mediated signal transduction GO:0007264 97 0.022
hemostasis GO:0007599 78 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
positive regulation of secretion GO:0051047 130 0.022
peptidyl proline modification GO:0018208 6 0.022
canonical wnt signaling pathway GO:0060070 130 0.021
meiosis i GO:0007127 60 0.021
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.021
purine containing compound metabolic process GO:0072521 311 0.021
stem cell development GO:0048864 219 0.021
leukocyte differentiation GO:0002521 342 0.021
asymmetric neuroblast division GO:0055059 1 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
striated muscle tissue development GO:0014706 293 0.021
internal peptidyl lysine acetylation GO:0018393 42 0.021
vascular process in circulatory system GO:0003018 62 0.021
positive regulation of protein secretion GO:0050714 52 0.020
myotube differentiation GO:0014902 105 0.020
dna dealkylation GO:0035510 11 0.020
ameboidal type cell migration GO:0001667 128 0.020
cardiocyte differentiation GO:0035051 87 0.020
muscle tissue morphogenesis GO:0060415 53 0.020
regulation of endopeptidase activity GO:0052548 89 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
multicellular organism growth GO:0035264 161 0.020
coagulation GO:0050817 78 0.020
regulation of nucleotide metabolic process GO:0006140 169 0.020
skeletal myofibril assembly GO:0014866 4 0.020
anion transport GO:0006820 177 0.020
ras protein signal transduction GO:0007265 77 0.020
digestive tract morphogenesis GO:0048546 147 0.020
regulation of actin cytoskeleton organization GO:0032956 84 0.020
regulation of tube size GO:0035150 57 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
interspecies interaction between organisms GO:0044419 83 0.020
cell type specific apoptotic process GO:0097285 268 0.020
telomere maintenance via telomerase GO:0007004 1 0.019
chemotaxis GO:0006935 247 0.019
pentose phosphate shunt GO:0006098 2 0.019
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.019
mesenchymal cell differentiation GO:0048762 107 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
protein import into nucleus GO:0006606 95 0.019
intrahepatic bile duct development GO:0035622 2 0.019
cardiac muscle tissue development GO:0048738 130 0.018
lymphocyte proliferation GO:0046651 164 0.018
tissue homeostasis GO:0001894 115 0.018
dna modification GO:0006304 50 0.018
photoreceptor cell development GO:0042461 40 0.018
multi multicellular organism process GO:0044706 109 0.018
response to organic cyclic compound GO:0014070 198 0.018
axon guidance GO:0007411 141 0.018
epithelial cell proliferation GO:0050673 174 0.017
cellular protein complex disassembly GO:0043624 36 0.017
purine nucleoside monophosphate metabolic process GO:0009126 81 0.017
actomyosin structure organization GO:0031032 56 0.017
regulation of organ morphogenesis GO:2000027 144 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
calcium ion transport GO:0006816 159 0.017
posttranscriptional gene silencing by rna GO:0035194 10 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
neural tube development GO:0021915 160 0.017
negative regulation of neuron apoptotic process GO:0043524 92 0.017
calcium ion transmembrane transport GO:0070588 85 0.016
asymmetric stem cell division GO:0098722 3 0.016
nucleoside phosphate biosynthetic process GO:1901293 79 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
response to inorganic substance GO:0010035 96 0.016
negative regulation of chromatin silencing GO:0031936 1 0.016
heart contraction GO:0060047 93 0.016
response to acid chemical GO:0001101 111 0.016
positive regulation of mrna metabolic process GO:1903313 17 0.016
positive regulation of organelle organization GO:0010638 128 0.016
neural tube formation GO:0001841 108 0.016
cyclic nucleotide metabolic process GO:0009187 59 0.016
skeletal muscle thin filament assembly GO:0030240 2 0.016
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.016
regulation of actin filament based process GO:0032970 99 0.016
digestive system development GO:0055123 200 0.016
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051439 1 0.015
kidney development GO:0001822 213 0.015
dendritic spine morphogenesis GO:0060997 22 0.015
placenta development GO:0001890 140 0.015
positive regulation of nucleotide metabolic process GO:0045981 114 0.015
meiotic cell cycle process GO:1903046 77 0.015
regulation of immunological synapse formation GO:2000520 2 0.015
endocytosis GO:0006897 168 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
cranial nerve morphogenesis GO:0021602 26 0.015
cellular response to lipid GO:0071396 145 0.015
amine metabolic process GO:0009308 45 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
carbohydrate metabolic process GO:0005975 230 0.015
cellular amino acid metabolic process GO:0006520 103 0.015
muscle fiber development GO:0048747 76 0.015
single organismal cell cell adhesion GO:0016337 131 0.015
positive regulation of protein export from nucleus GO:0046827 4 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
tube formation GO:0035148 140 0.015
coenzyme metabolic process GO:0006732 52 0.015
regulation of cell activation GO:0050865 289 0.015
positive regulation of dna templated transcription elongation GO:0032786 2 0.015
cell chemotaxis GO:0060326 81 0.015
regulation of mapk cascade GO:0043408 248 0.014
mitotic cytokinesis GO:0000281 4 0.014
nerve development GO:0021675 67 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
photoreceptor cell differentiation GO:0046530 52 0.014
response to metal ion GO:0010038 47 0.014
digestive tract development GO:0048565 190 0.014
muscle tissue development GO:0060537 308 0.014
peptidyl lysine modification GO:0018205 77 0.014
regulation of transcription by chromatin organization GO:0034401 0 0.014
epithelial cell development GO:0002064 159 0.014
alpha amino acid metabolic process GO:1901605 59 0.014
viral life cycle GO:0019058 36 0.014
cellular protein catabolic process GO:0044257 155 0.014
cell cell recognition GO:0009988 44 0.014
leukocyte migration GO:0050900 124 0.014
cranial nerve development GO:0021545 41 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
cellular amine metabolic process GO:0044106 44 0.014
regulation of transmembrane transport GO:0034762 128 0.014
vascular smooth muscle contraction GO:0014829 5 0.014
regulation of ion transport GO:0043269 215 0.014
synaptonemal complex organization GO:0070193 15 0.014
positive regulation of actin filament depolymerization GO:0030836 5 0.014
cilium morphogenesis GO:0060271 102 0.013
phospholipid metabolic process GO:0006644 87 0.013
cofactor biosynthetic process GO:0051188 41 0.013
epithelial tube formation GO:0072175 130 0.013
negative regulation of t cell activation GO:0050868 65 0.013
extracellular structure organization GO:0043062 148 0.013
peptidyl lysine acetylation GO:0018394 45 0.013
mitotic cell cycle GO:0000278 195 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
cell recognition GO:0008037 83 0.013
regulation of protein targeting GO:1903533 61 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
regulation of cell cycle GO:0051726 281 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
ribonucleoside monophosphate catabolic process GO:0009158 57 0.013
positive regulation of kinase activity GO:0033674 155 0.013
second messenger mediated signaling GO:0019932 73 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
purine containing compound catabolic process GO:0072523 213 0.013
protein dna complex subunit organization GO:0071824 28 0.013
mapk cascade GO:0000165 281 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
positive regulation of actin nucleation GO:0051127 3 0.013
histone modification GO:0016570 159 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.012
aromatic compound catabolic process GO:0019439 286 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
positive regulation of atpase activity GO:0032781 3 0.012
stem cell differentiation GO:0048863 268 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
rna dependent dna replication GO:0006278 3 0.012
response to growth factor GO:0070848 198 0.012
sensory perception GO:0007600 245 0.012
regulation of calcium ion transmembrane transport GO:1903169 20 0.012
negative regulation of molecular function GO:0044092 258 0.012
actin polymerization or depolymerization GO:0008154 54 0.012
morphogenesis of a polarized epithelium GO:0001738 37 0.012
microtubule based process GO:0007017 236 0.012
neuroblast proliferation GO:0007405 49 0.012
establishment or maintenance of cell polarity GO:0007163 86 0.012
response to organonitrogen compound GO:0010243 246 0.012
fertilization GO:0009566 127 0.012
actin cytoskeleton organization GO:0030036 220 0.012
calcium ion homeostasis GO:0055074 127 0.012
ear morphogenesis GO:0042471 118 0.012
response to amine GO:0014075 16 0.012
retina development in camera type eye GO:0060041 119 0.012
response to testosterone GO:0033574 3 0.012
myotube cell development GO:0014904 60 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.011
organelle localization GO:0051640 179 0.011
cell maturation GO:0048469 127 0.011
negative regulation of protein modification process GO:0031400 163 0.011
neural retina development GO:0003407 41 0.011
dendrite development GO:0016358 115 0.011
positive regulation of cardiac muscle contraction GO:0060452 2 0.011
membrane organization GO:0061024 245 0.011
pancreas development GO:0031016 57 0.011
dna replication GO:0006260 52 0.011
cardiac muscle tissue morphogenesis GO:0055008 44 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
regulation of hormone levels GO:0010817 211 0.011
skin development GO:0043588 220 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
regulation of system process GO:0044057 200 0.011
chromatin remodeling GO:0006338 32 0.011
connective tissue development GO:0061448 179 0.011
regulation of protein import into nucleus translocation GO:0033158 2 0.011
negative regulation of intracellular transport GO:0032387 38 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
positive regulation of intracellular transport GO:0032388 70 0.011
neuron projection guidance GO:0097485 141 0.011
positive regulation of rna splicing GO:0033120 12 0.011
cellular homeostasis GO:0019725 240 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
cardiac muscle cell differentiation GO:0055007 69 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
protein sumoylation GO:0016925 14 0.011
sulfur compound metabolic process GO:0006790 100 0.011
positive regulation of viral process GO:0048524 5 0.011
regulation of cell projection organization GO:0031344 206 0.011
nuclear transport GO:0051169 139 0.011
spindle assembly involved in female meiosis GO:0007056 3 0.011
leukocyte proliferation GO:0070661 172 0.010
translesion synthesis GO:0019985 1 0.010
optic nerve morphogenesis GO:0021631 6 0.010
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.010
nucleotide catabolic process GO:0009166 217 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010
mesenchymal cell development GO:0014031 93 0.010
cellular macromolecule catabolic process GO:0044265 206 0.010
hindbrain development GO:0030902 128 0.010
divalent inorganic cation transport GO:0072511 178 0.010
response to increased oxygen levels GO:0036296 2 0.010
regulation of anatomical structure size GO:0090066 178 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
organic acid transport GO:0015849 101 0.010
regulation of neuron death GO:1901214 134 0.010
mitochondrion organization GO:0007005 134 0.010
signal transduction in absence of ligand GO:0038034 55 0.010
cell adhesion GO:0007155 329 0.010
cellular lipid metabolic process GO:0044255 323 0.010

Tuba1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
congenital nervous system abnormality DOID:2490 0 0.165
lissencephaly DOID:0050453 0 0.165
physical disorder DOID:0080015 0 0.165
disease of anatomical entity DOID:7 0 0.097
nervous system disease DOID:863 0 0.097
sensory system disease DOID:0050155 0 0.097
nonsyndromic deafness DOID:0050563 0 0.022
auditory system disease DOID:2742 0 0.022
neuropathy DOID:870 0 0.012
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.012
joubert syndrome DOID:0050777 0 0.012
disease of cellular proliferation DOID:14566 0 0.010
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010