Mus musculus

0 known processes

Txndc5

thioredoxin domain containing 5

(Aliases: ERp46,PC-TRP,AL022641)

Txndc5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecule glycosylation GO:0043413 55 0.524
protein glycosylation GO:0006486 55 0.500
peptidyl proline hydroxylation GO:0019511 3 0.303
transmembrane transport GO:0055085 412 0.300
glycosylation GO:0070085 62 0.258
endomembrane system organization GO:0010256 147 0.230
carbohydrate derivative biosynthetic process GO:1901137 183 0.226
copii coated vesicle budding GO:0090114 2 0.212
membrane organization GO:0061024 245 0.187
cation transport GO:0006812 399 0.183
glycoprotein biosynthetic process GO:0009101 89 0.142
t cell activation GO:0042110 289 0.139
multicellular organism growth GO:0035264 161 0.129
ion transmembrane transport GO:0034220 361 0.127
regulation of transmembrane transport GO:0034762 128 0.124
glycoprotein metabolic process GO:0009100 116 0.119
cation transmembrane transport GO:0098655 266 0.118
protein hydroxylation GO:0018126 4 0.109
inorganic ion transmembrane transport GO:0098660 234 0.103
carbohydrate metabolic process GO:0005975 230 0.102
monocarboxylic acid metabolic process GO:0032787 191 0.100
inorganic cation transmembrane transport GO:0098662 207 0.099
response to endoplasmic reticulum stress GO:0034976 53 0.093
cytoplasmic transport GO:0016482 234 0.088
oxidation reduction process GO:0055114 342 0.088
positive regulation of apoptotic process GO:0043065 217 0.084
positive regulation of viral entry into host cell GO:0046598 3 0.083
cellular amino acid metabolic process GO:0006520 103 0.077
liver development GO:0001889 66 0.076
regulation of apoptotic signaling pathway GO:2001233 197 0.076
positive regulation of apoptotic signaling pathway GO:2001235 95 0.073
cellular amine metabolic process GO:0044106 44 0.071
regulation of t cell activation GO:0050863 170 0.071
regulation of ion transmembrane transport GO:0034765 119 0.067
metal ion homeostasis GO:0055065 189 0.067
regulation of cellular amine metabolic process GO:0033238 20 0.064
positive regulation of cell death GO:0010942 224 0.064
cellular nitrogen compound catabolic process GO:0044270 280 0.063
regulation of body fluid levels GO:0050878 162 0.062
regulation of ion transport GO:0043269 215 0.061
blood coagulation GO:0007596 76 0.060
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.059
blood circulation GO:0008015 195 0.058
localization within membrane GO:0051668 4 0.054
divalent inorganic cation transport GO:0072511 178 0.054
leukocyte differentiation GO:0002521 342 0.054
vesicle organization GO:0016050 60 0.052
regulation of leukocyte differentiation GO:1902105 159 0.051
response to metal ion GO:0010038 47 0.051
regulation of system process GO:0044057 200 0.050
protein n linked glycosylation GO:0006487 12 0.050
cation homeostasis GO:0055080 212 0.050
forebrain development GO:0030900 302 0.049
circulatory system process GO:0003013 197 0.049
nucleobase containing small molecule metabolic process GO:0055086 352 0.048
male gamete generation GO:0048232 285 0.048
cell adhesion GO:0007155 329 0.048
macromolecule catabolic process GO:0009057 281 0.047
positive regulation of ion transport GO:0043270 65 0.046
divalent inorganic cation homeostasis GO:0072507 138 0.046
negative regulation of fatty acid oxidation GO:0046322 5 0.045
transition metal ion transport GO:0000041 38 0.045
negative regulation of cellular component organization GO:0051129 194 0.045
gland development GO:0048732 330 0.045
skeletal system development GO:0001501 356 0.044
lymphocyte differentiation GO:0030098 242 0.043
endoplasmic reticulum unfolded protein response GO:0030968 19 0.043
epithalamus development GO:0021538 2 0.043
cellular lipid metabolic process GO:0044255 323 0.042
amine metabolic process GO:0009308 45 0.042
sulfur compound biosynthetic process GO:0044272 37 0.042
regulation of cellular ketone metabolic process GO:0010565 66 0.040
cellular chemical homeostasis GO:0055082 215 0.040
calcium ion homeostasis GO:0055074 127 0.039
regulation of actin filament polymerization GO:0030833 38 0.039
carboxylic acid catabolic process GO:0046395 51 0.038
cellular response to zinc ion starvation GO:0034224 2 0.038
regulation of lymphocyte activation GO:0051249 240 0.036
positive regulation of vesicle fusion GO:0031340 2 0.036
ubiquitin dependent protein catabolic process GO:0006511 129 0.036
bone development GO:0060348 120 0.036
epithelial tube morphogenesis GO:0060562 303 0.035
organic acid transport GO:0015849 101 0.035
regulation of actin nucleation GO:0051125 4 0.035
nucleotide metabolic process GO:0009117 332 0.035
response to unfolded protein GO:0006986 21 0.035
protein polymerization GO:0051258 57 0.034
peptidyl proline hydroxylation to 4 hydroxy l proline GO:0018401 2 0.034
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.034
purine containing compound metabolic process GO:0072521 311 0.034
wound healing GO:0042060 157 0.033
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.032
cellular carbohydrate metabolic process GO:0044262 119 0.032
cellular divalent inorganic cation homeostasis GO:0072503 127 0.032
cellular macromolecule catabolic process GO:0044265 206 0.032
actin filament polymerization GO:0030041 44 0.032
ossification GO:0001503 216 0.031
organic anion transport GO:0015711 137 0.031
arp2 3 complex mediated actin nucleation GO:0034314 3 0.031
cellular ion homeostasis GO:0006873 165 0.031
regulation of secretion by cell GO:1903530 249 0.031
purine nucleoside catabolic process GO:0006152 205 0.030
protein folding GO:0006457 28 0.030
actin filament organization GO:0007015 113 0.030
divalent metal ion transport GO:0070838 172 0.030
coagulation GO:0050817 78 0.029
proteasomal protein catabolic process GO:0010498 98 0.029
regulation of metal ion transport GO:0010959 106 0.029
entry into other organism involved in symbiotic interaction GO:0051828 15 0.029
nuclear membrane organization GO:0071763 4 0.028
regulation of interleukin 13 secretion GO:2000665 2 0.028
apoptotic signaling pathway GO:0097190 306 0.028
regulation of cell cell adhesion mediated by cadherin GO:2000047 2 0.028
t cell proliferation GO:0042098 120 0.028
neural tube closure GO:0001843 90 0.028
t cell differentiation GO:0030217 174 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
multicellular organismal homeostasis GO:0048871 164 0.026
regulation of nucleoside metabolic process GO:0009118 130 0.026
extracellular structure organization GO:0043062 148 0.026
heterocycle catabolic process GO:0046700 280 0.026
positive regulation of t helper 2 cell activation GO:2000570 2 0.026
cellular response to organic cyclic compound GO:0071407 87 0.026
immune effector process GO:0002252 321 0.026
regulation of nucleotide metabolic process GO:0006140 169 0.025
regulation of cell activation GO:0050865 289 0.025
spermatogenesis GO:0007283 284 0.025
cartilage development GO:0051216 140 0.025
leukocyte proliferation GO:0070661 172 0.025
calcium ion transport GO:0006816 159 0.025
positive regulation of programmed cell death GO:0043068 218 0.025
cellular metal ion homeostasis GO:0006875 151 0.025
heart contraction GO:0060047 93 0.024
regulation of cellular amino acid metabolic process GO:0006521 5 0.024
response to acid chemical GO:0001101 111 0.024
response to light stimulus GO:0009416 135 0.024
modification dependent protein catabolic process GO:0019941 133 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
movement in host environment GO:0052126 15 0.023
negative regulation of organelle organization GO:0010639 90 0.023
diencephalon development GO:0021536 63 0.023
muscle cell differentiation GO:0042692 261 0.022
establishment of protein localization to organelle GO:0072594 118 0.022
regulation of endocytosis GO:0030100 69 0.022
Fly
regulation of lymphocyte differentiation GO:0045619 107 0.022
aromatic compound catabolic process GO:0019439 286 0.022
platelet activation GO:0030168 40 0.022
anion transport GO:0006820 177 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
dna metabolic process GO:0006259 303 0.022
response to radiation GO:0009314 165 0.021
protein localization to organelle GO:0033365 185 0.021
peptidyl proline modification GO:0018208 6 0.021
cellular response to hormone stimulus GO:0032870 150 0.021
viral process GO:0016032 41 0.021
alcohol metabolic process GO:0006066 116 0.021
negative regulation of cell activation GO:0050866 111 0.021
positive regulation of leukocyte differentiation GO:1902107 86 0.021
cellular protein catabolic process GO:0044257 155 0.021
fatty acid transmembrane transport GO:1902001 1 0.021
ribose phosphate metabolic process GO:0019693 291 0.021
regulation of actin filament based process GO:0032970 99 0.020
appendage morphogenesis GO:0035107 149 0.020
response to osmotic stress GO:0006970 21 0.020
activation of adenylate cyclase activity GO:0007190 4 0.020
regulation of leukocyte proliferation GO:0070663 121 0.020
positive regulation of cell activation GO:0050867 158 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
regulation of fatty acid beta oxidation GO:0031998 1 0.020
regulation of t cell differentiation GO:0045580 83 0.020
ribonucleotide metabolic process GO:0009259 291 0.019
positive regulation of secretion GO:0051047 130 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
protein targeting GO:0006605 143 0.019
regulation of organelle organization GO:0033043 289 0.019
glucose homeostasis GO:0042593 128 0.019
cell growth GO:0016049 130 0.019
nucleoside metabolic process GO:0009116 246 0.019
carboxylic acid transport GO:0046942 100 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
posttranslational protein targeting to membrane GO:0006620 2 0.019
protein catabolic process GO:0030163 221 0.019
dna methylation GO:0006306 43 0.019
lateral inhibition GO:0046331 1 0.019
rho protein signal transduction GO:0007266 32 0.019
negative regulation of growth GO:0045926 99 0.018
inter male aggressive behavior GO:0002121 3 0.018
circadian regulation of gene expression GO:0032922 48 0.018
connective tissue development GO:0061448 179 0.018
negative regulation of cellular catabolic process GO:0031330 47 0.018
rna processing GO:0006396 105 0.018
regulation of actin polymerization or depolymerization GO:0008064 45 0.018
sequestering of metal ion GO:0051238 19 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
heart process GO:0003015 94 0.018
regulation of lipid storage GO:0010883 20 0.018
positive regulation of ral gtpase activity GO:0032852 4 0.018
hepaticobiliary system development GO:0061008 67 0.018
striated muscle cell development GO:0055002 125 0.018
cellular modified amino acid metabolic process GO:0006575 63 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
cellular homeostasis GO:0019725 240 0.017
maintenance of location GO:0051235 89 0.017
urogenital system development GO:0001655 261 0.017
response to organic cyclic compound GO:0014070 198 0.017
purine containing compound catabolic process GO:0072523 213 0.017
purine containing compound transmembrane transport GO:0072530 2 0.017
entry into host GO:0044409 15 0.017
actin polymerization or depolymerization GO:0008154 54 0.017
ribonucleotide biosynthetic process GO:0009260 59 0.017
hemostasis GO:0007599 78 0.017
regulation of hormone levels GO:0010817 211 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
hexose metabolic process GO:0019318 98 0.017
entry into host cell GO:0030260 15 0.017
golgi vesicle transport GO:0048193 30 0.017
regulation of protein secretion GO:0050708 82 0.017
regulation of cell motility GO:2000145 236 0.017
regulation of membrane potential GO:0042391 192 0.017
neural tube development GO:0021915 160 0.017
cytosolic calcium ion homeostasis GO:0051480 70 0.017
monosaccharide metabolic process GO:0005996 106 0.016
sulfur compound metabolic process GO:0006790 100 0.016
multicellular organismal reproductive behavior GO:0033057 23 0.016
multi multicellular organism process GO:0044706 109 0.016
regulation of interleukin 10 secretion GO:2001179 4 0.016
4 hydroxyproline metabolic process GO:0019471 5 0.016
lipid localization GO:0010876 126 0.016
mrna processing GO:0006397 63 0.016
regulation of intracellular transport GO:0032386 159 0.016
multi organism behavior GO:0051705 62 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
cellular protein complex assembly GO:0043623 116 0.016
lymphocyte proliferation GO:0046651 164 0.016
wnt signaling pathway GO:0016055 188 0.016
actin filament depolymerization GO:0030042 15 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
muscle system process GO:0003012 141 0.015
response to inorganic substance GO:0010035 96 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
morphogenesis of a branching epithelium GO:0061138 193 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
regulation of secretion GO:0051046 274 0.015
skin development GO:0043588 220 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
regulation of heart contraction GO:0008016 77 0.015
positive regulation of mrna processing GO:0050685 16 0.015
regulation of blood circulation GO:1903522 93 0.015
peptidyl amino acid modification GO:0018193 336 0.015
fatty acid metabolic process GO:0006631 121 0.015
mrna metabolic process GO:0016071 84 0.015
nucleotide catabolic process GO:0009166 217 0.015
positive regulation of lymphocyte activation GO:0051251 140 0.015
positive regulation of interleukin 10 secretion GO:2001181 1 0.015
protein targeting to membrane GO:0006612 20 0.015
cellular response to lipid GO:0071396 145 0.015
ameboidal type cell migration GO:0001667 128 0.014
vascular process in circulatory system GO:0003018 62 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.014
cellular calcium ion homeostasis GO:0006874 119 0.014
intracellular distribution of mitochondria GO:0048312 1 0.014
fat cell differentiation GO:0045444 160 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
Fly
negative regulation of synapse assembly GO:0051964 3 0.014
positive regulation of vasoconstriction GO:0045907 4 0.014
bone morphogenesis GO:0060349 78 0.014
small molecule catabolic process GO:0044282 71 0.014
embryonic skeletal system development GO:0048706 120 0.014
regulation of actin cytoskeleton organization GO:0032956 84 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
sequestering of calcium ion GO:0051208 18 0.014
sensory perception of taste GO:0050909 18 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
regulation of anatomical structure size GO:0090066 178 0.014
regulation of cytokine secretion GO:0050707 61 0.014
extracellular matrix organization GO:0030198 147 0.014
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
digestive system development GO:0055123 200 0.014
response to uv GO:0009411 44 0.014
regulation of cellular component biogenesis GO:0044087 181 0.013
rhythmic process GO:0048511 174 0.013
chromatin organization GO:0006325 206 0.013
positive regulation of interleukin 13 secretion GO:2000667 1 0.013
t helper 2 cell activation GO:0035712 2 0.013
regulation of protein complex assembly GO:0043254 83 0.013
interleukin 13 secretion GO:0072611 2 0.013
compound eye development GO:0048749 1 0.013
nucleoside catabolic process GO:0009164 206 0.013
protein localization to membrane GO:0072657 108 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
sodium ion transport GO:0006814 73 0.013
cell activation involved in immune response GO:0002263 126 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
regulation of fat cell differentiation GO:0045598 81 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
anion transmembrane transport GO:0098656 71 0.013
regulation of cell shape GO:0008360 39 0.013
defense response to other organism GO:0098542 197 0.013
regulation of cell projection organization GO:0031344 206 0.013
cellular ketone metabolic process GO:0042180 84 0.013
regulation of lymphocyte proliferation GO:0050670 117 0.013
purine nucleotide metabolic process GO:0006163 302 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
muscle contraction GO:0006936 101 0.013
regulation of neuron differentiation GO:0045664 281 0.013
regulation of homeostatic process GO:0032844 182 0.013
positive regulation of secretion by cell GO:1903532 114 0.013
heart morphogenesis GO:0003007 178 0.012
synaptic transmission GO:0007268 329 0.012
positive regulation of endocytosis GO:0045807 42 0.012
Fly
adaptive immune response GO:0002250 155 0.012
ras protein signal transduction GO:0007265 77 0.012
negative regulation of stress fiber assembly GO:0051497 4 0.012
mitochondrion organization GO:0007005 134 0.012
photoreceptor cell differentiation GO:0046530 52 0.012
neural precursor cell proliferation GO:0061351 121 0.012
multi organism reproductive behavior GO:0044705 29 0.012
carbohydrate homeostasis GO:0033500 128 0.012
positive regulation of leukocyte proliferation GO:0070665 73 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
negative regulation of phagocytosis GO:0050765 4 0.012
branching morphogenesis of an epithelial tube GO:0048754 159 0.012
positive regulation of camp metabolic process GO:0030816 19 0.012
cytokine secretion GO:0050663 72 0.012
response to uv a GO:0070141 1 0.012
regulation of mapk cascade GO:0043408 248 0.012
viral entry into host cell GO:0046718 15 0.012
regulation of cell cycle GO:0051726 281 0.012
nephron epithelium development GO:0072009 92 0.012
fibrinolysis GO:0042730 3 0.012
interaction with host GO:0051701 22 0.011
regulation of systemic arterial blood pressure GO:0003073 61 0.011
endochondral bone morphogenesis GO:0060350 50 0.011
detection of abiotic stimulus GO:0009582 60 0.011
regulation of mrna metabolic process GO:1903311 43 0.011
regulation of vesicle fusion GO:0031338 6 0.011
mrna splicing via spliceosome GO:0000398 43 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
response to organonitrogen compound GO:0010243 246 0.011
protein secretion GO:0009306 111 0.011
sensory organ morphogenesis GO:0090596 242 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
positive regulation of protein modification process GO:0031401 299 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
response to calcium ion GO:0051592 20 0.011
cargo loading into vesicle GO:0035459 3 0.011
regulation of t cell proliferation GO:0042129 92 0.011
appendage development GO:0048736 166 0.011
alpha beta t cell activation GO:0046631 91 0.011
regulation of protein transport GO:0051223 163 0.011
nucleoside transmembrane transport GO:1901642 4 0.011
endocytosis GO:0006897 168 0.011
Fly
methylation GO:0032259 134 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
positive regulation of glucose import in response to insulin stimulus GO:2001275 5 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
regulation of tube size GO:0035150 57 0.011
actin cytoskeleton organization GO:0030036 220 0.011
positive regulation of growth GO:0045927 104 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
organ growth GO:0035265 117 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
macromolecule methylation GO:0043414 120 0.011
positive regulation of interleukin 5 secretion GO:2000664 1 0.011
mitotic cytokinesis GO:0000281 4 0.011
detection of external stimulus GO:0009581 61 0.011
organic cyclic compound catabolic process GO:1901361 295 0.011
intracellular receptor signaling pathway GO:0030522 74 0.011
positive regulation of transmembrane transport GO:0034764 29 0.011
negative regulation of lymphocyte activation GO:0051250 91 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.010
camera type eye development GO:0043010 266 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
lipid transport GO:0006869 98 0.010
nucleotide sugar metabolic process GO:0009225 4 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
regulation of interleukin 5 secretion GO:2000662 2 0.010
nuclear transport GO:0051169 139 0.010
regulation of catecholamine metabolic process GO:0042069 10 0.010
negative regulation of cell cycle GO:0045786 123 0.010
mucopolysaccharide metabolic process GO:1903510 25 0.010
regulation of organ morphogenesis GO:2000027 144 0.010
regulation of osteoblast differentiation GO:0045667 67 0.010
fatty acid transport GO:0015908 28 0.010
purine nucleotide catabolic process GO:0006195 211 0.010
regulation of cell adhesion GO:0030155 154 0.010

Txndc5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
osteochondrodysplasia DOID:2256 0 0.177
bone development disease DOID:0080006 0 0.177
bone disease DOID:0080001 0 0.177
disease of anatomical entity DOID:7 0 0.177
musculoskeletal system disease DOID:17 0 0.177
connective tissue disease DOID:65 0 0.177
osteogenesis imperfecta DOID:12347 0 0.086
disease of cellular proliferation DOID:14566 0 0.026
cancer DOID:162 0 0.018
organ system cancer DOID:0050686 0 0.018
breast cancer DOID:1612 0 0.017
thoracic cancer DOID:5093 0 0.017
large intestine cancer DOID:5672 0 0.017
colon cancer DOID:219 0 0.017
gastrointestinal system cancer DOID:3119 0 0.017
intestinal cancer DOID:10155 0 0.017
colorectal cancer DOID:9256 0 0.017
central nervous system disease DOID:331 0 0.014
nervous system disease DOID:863 0 0.014