|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.489
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.428
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.422
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
21 |
0.400
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.384
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.381
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.368
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.280
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.278
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.270
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.247
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.235
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.233
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.223
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.207
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.202
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.200
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.186
|
Mouse |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.180
|
Fly |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.168
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.168
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.167
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.154
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.146
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.145
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.133
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.131
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.125
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.125
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.122
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.113
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.113
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.108
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.100
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.100
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.100
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.099
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.098
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.097
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.095
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.094
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.092
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.091
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.091
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.090
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.089
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.089
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.088
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.084
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.083
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.082
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.081
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.081
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.080
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.079
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.077
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.077
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.077
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.077
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.077
|
Fly |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.075
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.074
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.074
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.073
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.073
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.073
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.072
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.071
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.071
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.071
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.070
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.070
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.069
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.069
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.068
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.066
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.066
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.066
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.066
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.066
|
|
|
|
positive regulation of macroautophagy
|
GO:0016239 |
3 |
0.065
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.065
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.065
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.063
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.062
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.062
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.062
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.062
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.060
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.060
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.060
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.059
|
Fly |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.058
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.058
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.058
|
Mouse |
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.058
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.058
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.057
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.057
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.057
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.057
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.056
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.056
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.056
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.055
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.055
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.055
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.055
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.055
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.054
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.054
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.054
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.053
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.053
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.052
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.051
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.051
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.051
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.050
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.050
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.050
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.049
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.048
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.047
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.047
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.047
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.047
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.047
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.047
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.046
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.046
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.046
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.046
|
Fly |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.045
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.044
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.044
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.044
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
26 |
0.043
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.043
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.042
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.042
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.042
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.042
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.042
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.042
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.042
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.041
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.041
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.040
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.040
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.040
|
|
|
|
translation
|
GO:0006412 |
93 |
0.040
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.039
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.039
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.038
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.038
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.038
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.038
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.038
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.038
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.037
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.037
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.037
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.037
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.037
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.037
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.037
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.036
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.036
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.036
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.036
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.036
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.036
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.035
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.035
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.035
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.035
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.035
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.035
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.034
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.034
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.034
|
|
|
|
protein deubiquitination
|
GO:0016579 |
19 |
0.034
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.034
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.034
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.034
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.034
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.033
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.033
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.033
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.033
|
|
|
|
telomere maintenance
|
GO:0000723 |
19 |
0.033
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.033
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.033
|
|
|
|
glycosylation
|
GO:0070085 |
62 |
0.033
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.032
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.032
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.032
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.032
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.032
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.032
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.031
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.031
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.031
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.031
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.031
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.030
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.030
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.030
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.030
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.030
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.030
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.030
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.030
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.030
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.029
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.029
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.029
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.029
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.029
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.029
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.029
|
Fly |
|
|
endocrine system development
|
GO:0035270 |
98 |
0.029
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.028
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.028
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.028
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.028
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.028
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.028
|
|
|
|
intracellular distribution of mitochondria
|
GO:0048312 |
1 |
0.028
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.028
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.028
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.028
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.028
|
|
|
|
maternal process involved in female pregnancy
|
GO:0060135 |
32 |
0.028
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.028
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.027
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.027
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.027
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.027
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.027
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.027
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.027
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.027
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.027
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.027
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.027
|
Human |
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.027
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.027
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.026
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.026
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.026
|
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.026
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.026
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
34 |
0.026
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.026
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.026
|
|
|
|
cerebellum development
|
GO:0021549 |
77 |
0.026
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.026
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.026
|
|
|
|
atp metabolic process
|
GO:0046034 |
75 |
0.026
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.025
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.025
|
|
|
|
positive regulation of mitotic sister chromatid separation
|
GO:1901970 |
2 |
0.025
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
31 |
0.025
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.025
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.025
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.025
|
|
|
|
hindbrain morphogenesis
|
GO:0021575 |
46 |
0.025
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.025
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.025
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.025
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.025
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.024
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.024
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.024
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.024
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.024
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.024
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.024
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.024
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.024
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.024
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.024
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.024
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.024
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.024
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.024
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
80 |
0.023
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.023
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.023
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.023
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.023
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.023
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.023
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.023
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.023
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.023
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.023
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.023
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.022
|
Fly |
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.022
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.022
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.022
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.022
|
|
|
|
cell aging
|
GO:0007569 |
35 |
0.022
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.022
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.022
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.022
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.022
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.022
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.021
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.021
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.021
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.021
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.021
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.021
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.021
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.021
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.021
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.021
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.021
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.021
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.021
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.021
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.020
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.020
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.020
|
|
|
|
memory
|
GO:0007613 |
58 |
0.020
|
Fly |
|
|
ear development
|
GO:0043583 |
200 |
0.020
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.020
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.020
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.020
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.020
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.020
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.020
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.020
|
Fly |
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.020
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.019
|
|
|
|
cerebellum morphogenesis
|
GO:0021587 |
42 |
0.019
|
|
|
|
gene silencing
|
GO:0016458 |
38 |
0.019
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.019
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
35 |
0.019
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.019
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.019
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.019
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.019
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.019
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.019
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
22 |
0.019
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.018
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.018
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.018
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.018
|
|
|
|
cajal body organization
|
GO:0030576 |
1 |
0.018
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.018
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.018
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.018
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.018
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.018
|
|
|
|
mitochondrion transport along microtubule
|
GO:0047497 |
3 |
0.018
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.018
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
59 |
0.018
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.018
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.018
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.018
|
|
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.018
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
35 |
0.018
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.018
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.018
|
Fly |
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.018
|
|
|
|
monoubiquitinated protein deubiquitination
|
GO:0035520 |
2 |
0.018
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
51 |
0.018
|
|
|
|
ovarian follicle development
|
GO:0001541 |
40 |
0.017
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.017
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.017
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.017
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.017
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.017
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.017
|
|
|
|
mitotic g2 dna damage checkpoint
|
GO:0007095 |
8 |
0.017
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.017
|
|
|
|
establishment of mitochondrion localization
|
GO:0051654 |
4 |
0.017
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.017
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.017
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
58 |
0.017
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.017
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.017
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.017
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.017
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.017
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.017
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.017
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.016
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.016
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.016
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.016
|
|
|
|
columnar cuboidal epithelial cell development
|
GO:0002066 |
29 |
0.016
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.016
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.016
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
23 |
0.016
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.016
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.016
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.016
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.016
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.016
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
57 |
0.016
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.016
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.016
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.016
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.016
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.015
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.015
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.015
|
|
|
|
male gonad development
|
GO:0008584 |
88 |
0.015
|
|
|
|
mitochondrial transport
|
GO:0006839 |
36 |
0.015
|
|
|
|
response to heat
|
GO:0009408 |
27 |
0.015
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.015
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.015
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.015
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.015
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.015
|
|
|
|
metaphase plate congression
|
GO:0051310 |
2 |
0.015
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.015
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.015
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.015
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.015
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.015
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.015
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.015
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.015
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.015
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.014
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.014
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.014
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.014
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.014
|
|
|
|
hypophysis morphogenesis
|
GO:0048850 |
3 |
0.014
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.014
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.014
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.014
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.014
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.014
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
36 |
0.014
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.014
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.014
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.014
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.014
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.014
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.014
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.014
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.014
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.014
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.014
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.014
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.014
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.013
|
|
|
|
ribonucleoprotein complex localization
|
GO:0071166 |
1 |
0.013
|
|
|
|
transforming growth factor beta2 production
|
GO:0032906 |
2 |
0.013
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.013
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.013
|
|
|
|
megakaryocyte differentiation
|
GO:0030219 |
26 |
0.013
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.013
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.013
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
57 |
0.013
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.013
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.013
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.013
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.013
|
|
|
|
establishment of rna localization
|
GO:0051236 |
18 |
0.013
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.013
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.013
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.013
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.013
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.013
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
102 |
0.013
|
|
|
|
mitochondrial outer membrane permeabilization involved in programmed cell death
|
GO:1902686 |
11 |
0.013
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.013
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
57 |
0.013
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.013
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.013
|
|
|
|
mrna 3 end processing
|
GO:0031124 |
16 |
0.012
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.012
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.012
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.012
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.012
|
|
|
|
inner ear receptor cell differentiation
|
GO:0060113 |
61 |
0.012
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
35 |
0.012
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.012
|
|
|
|
negative regulation of translation
|
GO:0017148 |
22 |
0.012
|
|
