Mus musculus

36 known processes

Ung

uracil DNA glycosylase

(Aliases: UNG1,UNG2)

Ung biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 207 0.194
Worm
dna repair GO:0006281 107 0.159
Worm
dna metabolic process GO:0006259 303 0.134
dna recombination GO:0006310 92 0.129
cellular amino acid metabolic process GO:0006520 103 0.124
intrinsic apoptotic signaling pathway GO:0097193 132 0.116
apoptotic signaling pathway GO:0097190 306 0.097
male gamete generation GO:0048232 285 0.088
nucleobase containing small molecule metabolic process GO:0055086 352 0.087
spermatogenesis GO:0007283 284 0.083
meiotic nuclear division GO:0007126 115 0.079
regulation of cellular amine metabolic process GO:0033238 20 0.078
cell fate commitment GO:0045165 210 0.078
negative regulation of molecular function GO:0044092 258 0.078
rhythmic process GO:0048511 174 0.078
membrane organization GO:0061024 245 0.075
dna biosynthetic process GO:0071897 22 0.072
dna endoreduplication GO:0042023 4 0.069
cell cycle g1 s phase transition GO:0044843 57 0.066
folic acid containing compound metabolic process GO:0006760 3 0.066
organelle fission GO:0048285 170 0.065
nuclear dna replication GO:0033260 3 0.064
regulation of cellular amino acid metabolic process GO:0006521 5 0.064
dna dependent dna replication GO:0006261 24 0.062
organic cyclic compound catabolic process GO:1901361 295 0.060
regulation of apoptotic signaling pathway GO:2001233 197 0.058
multicellular organism growth GO:0035264 161 0.057
regulation of anatomical structure size GO:0090066 178 0.056
macromolecule catabolic process GO:0009057 281 0.055
cellular amine metabolic process GO:0044106 44 0.054
regulation of transferase activity GO:0051338 263 0.054
cellular macromolecule catabolic process GO:0044265 206 0.053
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.052
negative regulation of cell proliferation GO:0008285 296 0.052
organelle assembly GO:0070925 177 0.051
nucleoside catabolic process GO:0009164 206 0.050
protein ubiquitination GO:0016567 171 0.049
positive regulation of apoptotic process GO:0043065 217 0.049
heterocycle catabolic process GO:0046700 280 0.048
positive regulation of cell death GO:0010942 224 0.047
double strand break repair GO:0006302 48 0.047
cellular ketone metabolic process GO:0042180 84 0.046
purine ribonucleoside metabolic process GO:0046128 241 0.045
cation transport GO:0006812 399 0.045
chromatin organization GO:0006325 206 0.045
purine containing compound metabolic process GO:0072521 311 0.044
camera type eye development GO:0043010 266 0.044
double strand break repair via homologous recombination GO:0000724 21 0.043
protein modification by small protein conjugation or removal GO:0070647 207 0.043
regulation of cell cycle process GO:0010564 160 0.043
nucleoside monophosphate metabolic process GO:0009123 85 0.043
meiotic cell cycle process GO:1903046 77 0.043
lateral inhibition GO:0046331 1 0.043
aromatic compound catabolic process GO:0019439 286 0.042
purine nucleoside catabolic process GO:0006152 205 0.042
nucleoside triphosphate metabolic process GO:0009141 230 0.041
placenta development GO:0001890 140 0.040
gland development GO:0048732 330 0.040
nucleoside phosphate metabolic process GO:0006753 338 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.039
endomembrane system organization GO:0010256 147 0.038
endocytosis GO:0006897 168 0.038
glial cell differentiation GO:0010001 131 0.038
protein processing GO:0016485 163 0.038
microtubule cytoskeleton organization GO:0000226 157 0.037
locomotory behavior GO:0007626 195 0.037
response to radiation GO:0009314 165 0.037
blastocyst development GO:0001824 80 0.037
cell division GO:0051301 120 0.037
organonitrogen compound catabolic process GO:1901565 264 0.036
purine ribonucleotide metabolic process GO:0009150 290 0.036
regulation of cytokine production GO:0001817 266 0.036
amine metabolic process GO:0009308 45 0.036
negative regulation of phosphorus metabolic process GO:0010563 184 0.036
cytokine production GO:0001816 319 0.036
response to organonitrogen compound GO:0010243 246 0.035
nucleoside phosphate catabolic process GO:1901292 222 0.035
l serine metabolic process GO:0006563 2 0.035
epithelial tube morphogenesis GO:0060562 303 0.035
meiosis i GO:0007127 60 0.034
purine nucleoside metabolic process GO:0042278 241 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.033
response to light stimulus GO:0009416 135 0.033
transmembrane transport GO:0055085 412 0.033
regulation of cellular component size GO:0032535 121 0.033
purine nucleotide metabolic process GO:0006163 302 0.032
signal transduction by p53 class mediator GO:0072331 51 0.032
positive regulation of cell development GO:0010720 237 0.032
regulation of binding GO:0051098 111 0.031
regulation of protein kinase activity GO:0045859 232 0.031
protein modification by small protein conjugation GO:0032446 187 0.030
positive regulation of programmed cell death GO:0043068 218 0.030
response to organic cyclic compound GO:0014070 198 0.029
germ cell development GO:0007281 185 0.029
regulation of circadian sleep wake cycle GO:0042749 3 0.029
gonad development GO:0008406 141 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
organophosphate catabolic process GO:0046434 232 0.028
oxidation reduction process GO:0055114 342 0.028
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.028
dna replication GO:0006260 52 0.028
posttranscriptional regulation of gene expression GO:0010608 155 0.027
cell adhesion GO:0007155 329 0.027
regulation of proteolysis GO:0030162 164 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.027
digestive tract development GO:0048565 190 0.026
respiratory tube development GO:0030323 167 0.026
regulation of hydrolase activity GO:0051336 246 0.026
mitotic cell cycle GO:0000278 195 0.026
female gamete generation GO:0007292 74 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
cellular response to organonitrogen compound GO:0071417 145 0.025
ras protein signal transduction GO:0007265 77 0.025
regulation of nuclear cell cycle dna replication GO:0033262 2 0.025
oogenesis GO:0048477 56 0.025
respiratory system development GO:0060541 190 0.024
mitotic chromosome condensation GO:0007076 1 0.024
negative regulation of cell size GO:0045792 3 0.024
carbohydrate derivative catabolic process GO:1901136 231 0.024
morphogenesis of a branching epithelium GO:0061138 193 0.024
glycosyl compound metabolic process GO:1901657 246 0.024
cell type specific apoptotic process GO:0097285 268 0.024
nucleoside metabolic process GO:0009116 246 0.024
stem cell development GO:0048864 219 0.024
cellular protein complex assembly GO:0043623 116 0.024
positive regulation of nervous system development GO:0051962 221 0.024
regulation of cell size GO:0008361 72 0.024
muscle cell differentiation GO:0042692 261 0.023
regulation of organelle organization GO:0033043 289 0.023
sensory organ morphogenesis GO:0090596 242 0.023
ribonucleoside catabolic process GO:0042454 206 0.023
ribonucleoside monophosphate metabolic process GO:0009161 80 0.023
ion transmembrane transport GO:0034220 361 0.023
digestive system development GO:0055123 200 0.022
rna catabolic process GO:0006401 29 0.022
branching morphogenesis of an epithelial tube GO:0048754 159 0.022
glucose homeostasis GO:0042593 128 0.022
ribonucleoside triphosphate catabolic process GO:0009203 199 0.022
mapk cascade GO:0000165 281 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
development of primary sexual characteristics GO:0045137 143 0.022
cellular response to abiotic stimulus GO:0071214 56 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.021
negative regulation of cell development GO:0010721 169 0.021
regulation of neuron differentiation GO:0045664 281 0.021
b cell activation GO:0042113 161 0.021
positive regulation of cell cycle phase transition GO:1901989 17 0.021
chromatin modification GO:0016568 187 0.021
engulfment of apoptotic cell GO:0043652 3 0.021
intracellular mrna localization GO:0008298 4 0.021
nucleotide metabolic process GO:0009117 332 0.020
alpha amino acid metabolic process GO:1901605 59 0.020
organic anion transport GO:0015711 137 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.019
regulation of embryonic development GO:0045995 71 0.019
morphogenesis of a branching structure GO:0001763 203 0.019
protein maturation GO:0051604 176 0.019
mitochondrion organization GO:0007005 134 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
regulation of mitotic cell cycle phase transition GO:1901990 73 0.019
rna processing GO:0006396 105 0.019
extracellular structure organization GO:0043062 148 0.019
proteasomal protein catabolic process GO:0010498 98 0.019
heterochromatin organization GO:0070828 4 0.019
recombinational repair GO:0000725 21 0.018
purine nucleoside monophosphate metabolic process GO:0009126 81 0.018
regulation of actin filament based process GO:0032970 99 0.018
female gonad development GO:0008585 71 0.018
negative regulation of protein modification process GO:0031400 163 0.018
actin cytoskeleton organization GO:0030036 220 0.018
immune effector process GO:0002252 321 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
leukocyte differentiation GO:0002521 342 0.018
base excision repair GO:0006284 9 0.018
Worm
positive regulation of protein modification process GO:0031401 299 0.017
cell cell signaling involved in cell fate commitment GO:0045168 35 0.017
sensory perception GO:0007600 245 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.017
positive regulation of growth GO:0045927 104 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
liver development GO:0001889 66 0.017
urogenital system development GO:0001655 261 0.017
negative regulation of immune system process GO:0002683 209 0.017
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
regulation of response to wounding GO:1903034 189 0.017
carbohydrate homeostasis GO:0033500 128 0.017
peptidyl amino acid modification GO:0018193 336 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.017
divalent metal ion transport GO:0070838 172 0.017
positive regulation of cell cycle process GO:0090068 61 0.017
regulation of cell activation GO:0050865 289 0.017
positive regulation of proteolysis GO:0045862 85 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
nitrogen compound transport GO:0071705 271 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
circadian rhythm GO:0007623 114 0.017
protein dna complex subunit organization GO:0071824 28 0.017
regulation of cell cycle phase transition GO:1901987 77 0.016
positive regulation of transferase activity GO:0051347 167 0.016
carbohydrate metabolic process GO:0005975 230 0.016
connective tissue development GO:0061448 179 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
epithelial cell proliferation GO:0050673 174 0.016
regulation of hormone levels GO:0010817 211 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
myosin filament assembly GO:0031034 2 0.016
regulation of kinase activity GO:0043549 249 0.016
mitotic cell cycle process GO:1903047 159 0.016
protein catabolic process GO:0030163 221 0.016
purine containing compound catabolic process GO:0072523 213 0.016
peptidyl serine phosphorylation GO:0018105 74 0.016
organism emergence from protective structure GO:0071684 4 0.016
production of molecular mediator of immune response GO:0002440 103 0.016
genitalia development GO:0048806 37 0.016
female sex differentiation GO:0046660 84 0.016
negative regulation of nervous system development GO:0051961 156 0.016
homeostasis of number of cells GO:0048872 210 0.016
cellular response to cytokine stimulus GO:0071345 189 0.016
positive regulation of neuron differentiation GO:0045666 141 0.016
regionalization GO:0003002 337 0.016
cellular homeostasis GO:0019725 240 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
regulation of cysteine type endopeptidase activity GO:2000116 65 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
divalent inorganic cation transport GO:0072511 178 0.016
regulation of cell cycle GO:0051726 281 0.016
nucleotide catabolic process GO:0009166 217 0.016
t cell activation GO:0042110 289 0.016
lymphocyte differentiation GO:0030098 242 0.015
oocyte anterior posterior axis specification GO:0007314 2 0.015
negative regulation of cell cycle GO:0045786 123 0.015
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.015
purine ribonucleotide catabolic process GO:0009154 208 0.015
regulation of membrane potential GO:0042391 192 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
covalent chromatin modification GO:0016569 163 0.015
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.015
regulation of translation GO:0006417 71 0.015
meiotic cell cycle GO:0051321 122 0.015
chromatin assembly GO:0031497 13 0.015
lymphocyte proliferation GO:0046651 164 0.015
regulation of chromosome organization GO:0033044 83 0.014
protein polymerization GO:0051258 57 0.014
mitotic sister chromatid cohesion GO:0007064 1 0.014
cell maturation GO:0048469 127 0.014
protein oligomerization GO:0051259 67 0.014
nuclear division GO:0000280 158 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
compound eye development GO:0048749 1 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
gliogenesis GO:0042063 141 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
nucleobase biosynthetic process GO:0046112 3 0.014
single organism cell adhesion GO:0098602 156 0.014
macromolecule methylation GO:0043414 120 0.014
negative regulation of binding GO:0051100 39 0.014
response to peptide hormone GO:0043434 127 0.014
cellular response to epidermal growth factor stimulus GO:0071364 4 0.014
development of primary female sexual characteristics GO:0046545 73 0.014
leukocyte proliferation GO:0070661 172 0.014
cell cycle switching GO:0060184 1 0.014
stem cell proliferation GO:0072089 117 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
dna integrity checkpoint GO:0031570 28 0.013
negative regulation of mitotic cell cycle GO:0045930 58 0.013
positive regulation of organelle organization GO:0010638 128 0.013
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 3 0.013
multicellular organismal signaling GO:0035637 91 0.013
multi multicellular organism process GO:0044706 109 0.013
transmission of nerve impulse GO:0019226 76 0.013
regulation of mapk cascade GO:0043408 248 0.013
positive regulation of immune effector process GO:0002699 107 0.013
regulation of cell division GO:0051302 76 0.013
stem cell differentiation GO:0048863 268 0.013
glial cell development GO:0021782 54 0.013
regulation of cellular response to stress GO:0080135 159 0.013
hepaticobiliary system development GO:0061008 67 0.013
nucleus organization GO:0006997 45 0.013
gonad morphogenesis GO:0035262 1 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
anion transport GO:0006820 177 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
rna splicing GO:0008380 54 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
lipid homeostasis GO:0055088 63 0.013
cellular response to hormone stimulus GO:0032870 150 0.012
cellular protein catabolic process GO:0044257 155 0.012
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.012
translation GO:0006412 93 0.012
small molecule catabolic process GO:0044282 71 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
regulation of neuron projection development GO:0010975 169 0.012
regulation of sister chromatid cohesion GO:0007063 5 0.012
developmental cell growth GO:0048588 84 0.012
regulation of intracellular transport GO:0032386 159 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.012
carboxylic acid transport GO:0046942 100 0.012
cellularization GO:0007349 1 0.012
neuroblast differentiation GO:0014016 2 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
immunoglobulin mediated immune response GO:0016064 69 0.012
dna replication initiation GO:0006270 5 0.012
innate immune response GO:0045087 157 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
methylation GO:0032259 134 0.012
regulation of circadian rhythm GO:0042752 58 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
response to extracellular stimulus GO:0009991 127 0.012
action potential GO:0001508 78 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
dna duplex unwinding GO:0032508 7 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.012
chemotaxis GO:0006935 247 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
regulation of rna stability GO:0043487 26 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
cation transmembrane transport GO:0098655 266 0.012
striated muscle tissue development GO:0014706 293 0.012
circulatory system process GO:0003013 197 0.012
intracellular protein transport GO:0006886 204 0.012
regulation of secretion GO:0051046 274 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
myosin filament organization GO:0031033 3 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.011
response to lipopolysaccharide GO:0032496 128 0.011
response to inorganic substance GO:0010035 96 0.011
axonogenesis GO:0007409 274 0.011
skeletal system development GO:0001501 356 0.011
small molecule biosynthetic process GO:0044283 132 0.011
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.011
atp metabolic process GO:0046034 75 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
regulation of actin polymerization or depolymerization GO:0008064 45 0.011
myeloid cell differentiation GO:0030099 233 0.011
cellular response to peptide GO:1901653 92 0.011
regulation of defense response GO:0031347 233 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
muscle cell development GO:0055001 133 0.011
calcium ion transport GO:0006816 159 0.011
regulation of homeostatic process GO:0032844 182 0.011
developmental maturation GO:0021700 193 0.011
male gonad development GO:0008584 88 0.011
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.011
protein localization to organelle GO:0033365 185 0.011
regulation of neural precursor cell proliferation GO:2000177 70 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
meiotic dna repair synthesis GO:0000711 4 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
purine nucleobase metabolic process GO:0006144 4 0.011
regulation of cell migration GO:0030334 219 0.011
organelle localization GO:0051640 179 0.011
digestive tract morphogenesis GO:0048546 147 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
regulation of peptidase activity GO:0052547 96 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
cellular response to external stimulus GO:0071496 88 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
response to purine containing compound GO:0014074 28 0.011
response to growth factor GO:0070848 198 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
antimicrobial peptide biosynthetic process GO:0002777 2 0.011
peptidyl serine modification GO:0018209 83 0.011
amide transport GO:0042886 138 0.011
dna methylation involved in gamete generation GO:0043046 15 0.011
regulation of cell projection organization GO:0031344 206 0.011
pole plasm assembly GO:0007315 2 0.011
response to epidermal growth factor GO:0070849 4 0.011
kidney development GO:0001822 213 0.011
humoral immune response GO:0006959 57 0.011
regulation of endopeptidase activity GO:0052548 89 0.011
eye photoreceptor cell differentiation GO:0001754 41 0.011
mitotic recombination GO:0006312 3 0.011
cellular response to lipid GO:0071396 145 0.011
ribonucleoside monophosphate catabolic process GO:0009158 57 0.010
cytoplasmic transport GO:0016482 234 0.010
maintenance of location GO:0051235 89 0.010
mesenchymal cell differentiation GO:0048762 107 0.010
adaptive immune response GO:0002250 155 0.010
blood circulation GO:0008015 195 0.010
chromosome segregation GO:0007059 48 0.010
response to nutrient levels GO:0031667 109 0.010
pteridine containing compound metabolic process GO:0042558 5 0.010
regulation of ion transport GO:0043269 215 0.010
interleukin 6 production GO:0032635 58 0.010
actin polymerization or depolymerization GO:0008154 54 0.010
chromosome organization involved in meiosis GO:0070192 39 0.010
regulation of stem cell proliferation GO:0072091 78 0.010
oocyte construction GO:0007308 2 0.010
negative regulation of transferase activity GO:0051348 85 0.010
meiotic chromosome segregation GO:0045132 19 0.010
hatching GO:0035188 4 0.010

Ung disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.065
disease of cellular proliferation DOID:14566 0 0.065
organ system cancer DOID:0050686 0 0.064
disease of metabolism DOID:0014667 0 0.033
inherited metabolic disorder DOID:655 0 0.024
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
gastrointestinal system cancer DOID:3119 0 0.018
thoracic cancer DOID:5093 0 0.012
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.011
large intestine cancer DOID:5672 0 0.011
intestinal cancer DOID:10155 0 0.011
immune system cancer DOID:0060083 0 0.010
hematologic cancer DOID:2531 0 0.010