Mus musculus

25 known processes

Uros

uroporphyrinogen III synthase

(Aliases: AI415298,Uros3)

Uros biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cofactor biosynthetic process GO:0051188 41 0.281
iron ion homeostasis GO:0055072 36 0.255
cofactor metabolic process GO:0051186 80 0.191
organonitrogen compound biosynthetic process GO:1901566 192 0.153
myeloid cell differentiation GO:0030099 233 0.148
transmembrane transport GO:0055085 412 0.144
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 12 0.124
porphyrin containing compound biosynthetic process GO:0006779 16 0.124
amino acid transport GO:0006865 61 0.123
tetrapyrrole metabolic process GO:0033013 22 0.123
anion transport GO:0006820 177 0.122
homeostasis of number of cells GO:0048872 210 0.121
porphyrin containing compound metabolic process GO:0006778 22 0.114
intracellular protein transport GO:0006886 204 0.094
cation transmembrane transport GO:0098655 266 0.085
multicellular organismal iron ion homeostasis GO:0060586 8 0.083
inorganic anion transport GO:0015698 43 0.080
ion transmembrane transport GO:0034220 361 0.076
erythrocyte differentiation GO:0030218 88 0.074
inorganic cation transmembrane transport GO:0098662 207 0.073
divalent metal ion transport GO:0070838 172 0.072
cellular amino acid metabolic process GO:0006520 103 0.072
myeloid cell homeostasis GO:0002262 114 0.065
inorganic ion transmembrane transport GO:0098660 234 0.062
heme biosynthetic process GO:0006783 12 0.061
protein processing GO:0016485 163 0.060
immune effector process GO:0002252 321 0.055
cytoplasmic transport GO:0016482 234 0.053
carboxylic acid transport GO:0046942 100 0.052
cation transport GO:0006812 399 0.051
negative regulation of protein metabolic process GO:0051248 282 0.051
divalent inorganic cation transport GO:0072511 178 0.050
cation homeostasis GO:0055080 212 0.049
response to iron ion GO:0010039 4 0.049
protein maturation GO:0051604 176 0.048
transition metal ion homeostasis GO:0055076 54 0.047
spermatogenesis GO:0007283 284 0.046
tetrapyrrole biosynthetic process GO:0033014 16 0.043
establishment of protein localization to organelle GO:0072594 118 0.043
cytokine production GO:0001816 319 0.042
cellular ketone metabolic process GO:0042180 84 0.042
posttranscriptional regulation of gene expression GO:0010608 155 0.041
protein targeting GO:0006605 143 0.040
regulation of cytokine production GO:0001817 266 0.040
cellular ion homeostasis GO:0006873 165 0.038
nuclear transport GO:0051169 139 0.038
organic acid transport GO:0015849 101 0.037
t cell activation GO:0042110 289 0.036
regulation of proteolysis GO:0030162 164 0.036
arginine transport GO:0015809 4 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
negative regulation of cytokine production GO:0001818 84 0.035
protein localization to organelle GO:0033365 185 0.034
meiotic cell cycle process GO:1903046 77 0.034
organelle fission GO:0048285 170 0.032
nuclear division GO:0000280 158 0.032
membrane organization GO:0061024 245 0.031
activation of cysteine type endopeptidase activity GO:0097202 27 0.031
metal ion homeostasis GO:0055065 189 0.031
cellular metal ion homeostasis GO:0006875 151 0.031
organic anion transport GO:0015711 137 0.030
positive regulation of peptidase activity GO:0010952 49 0.030
microtubule based process GO:0007017 236 0.029
heme metabolic process GO:0042168 16 0.029
protein localization to nucleus GO:0034504 121 0.028
mitotic cell cycle process GO:1903047 159 0.028
l amino acid transport GO:0015807 32 0.028
amine metabolic process GO:0009308 45 0.028
t cell proliferation GO:0042098 120 0.027
protein import into nucleus GO:0006606 95 0.027
nucleocytoplasmic transport GO:0006913 139 0.027
microtubule cytoskeleton organization GO:0000226 157 0.027
protein import GO:0017038 101 0.027
regulation of organelle organization GO:0033043 289 0.026
regulation of reactive oxygen species metabolic process GO:2000377 40 0.026
defense response to other organism GO:0098542 197 0.025
regulation of ph GO:0006885 26 0.025
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.025
positive regulation of protein modification process GO:0031401 299 0.025
regulation of cardiac muscle cell membrane potential GO:0086036 3 0.024
single organism nuclear import GO:1902593 95 0.024
developmental maturation GO:0021700 193 0.024
learning or memory GO:0007611 148 0.023
negative regulation of cellular amine metabolic process GO:0033239 1 0.023
positive regulation of proteolysis GO:0045862 85 0.023
cellular response to dna damage stimulus GO:0006974 207 0.023
cellular homeostasis GO:0019725 240 0.023
cellular amine metabolic process GO:0044106 44 0.022
pigment biosynthetic process GO:0046148 26 0.022
lymphocyte proliferation GO:0046651 164 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.021
copper ion transmembrane transport GO:0035434 5 0.021
leukocyte proliferation GO:0070661 172 0.021
cell type specific apoptotic process GO:0097285 268 0.021
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 12 0.021
regulation of intracellular transport GO:0032386 159 0.021
regulation of hydrolase activity GO:0051336 246 0.021
hydrogen ion transmembrane transport GO:1902600 25 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
transmission of nerve impulse GO:0019226 76 0.021
positive regulation of potassium ion transport GO:0043268 3 0.021
purine containing compound metabolic process GO:0072521 311 0.020
nuclear import GO:0051170 95 0.020
macromolecule catabolic process GO:0009057 281 0.020
male gamete generation GO:0048232 285 0.020
t cell mediated immunity GO:0002456 50 0.020
regulation of cytoskeleton organization GO:0051493 122 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
positive regulation of protein kinase activity GO:0045860 144 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
mitotic cell cycle GO:0000278 195 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.019
muscle tissue development GO:0060537 308 0.019
hydrogen transport GO:0006818 35 0.019
peptidyl amino acid modification GO:0018193 336 0.019
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.019
inflammatory response GO:0006954 244 0.019
leukocyte activation involved in immune response GO:0002366 126 0.018
pigment metabolic process GO:0042440 32 0.018
positive regulation of endopeptidase activity GO:0010950 43 0.018
regulation of cell activation GO:0050865 289 0.018
spermatid development GO:0007286 108 0.018
positive regulation of potassium ion transmembrane transporter activity GO:1901018 1 0.018
carboxylic acid biosynthetic process GO:0046394 86 0.018
negative regulation of complement activation GO:0045916 3 0.018
cell maturation GO:0048469 127 0.018
spermatid differentiation GO:0048515 115 0.018
defense response to protozoan GO:0042832 25 0.018
positive regulation of leukocyte proliferation GO:0070665 73 0.018
regulation of peptidase activity GO:0052547 96 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
oxidation reduction process GO:0055114 342 0.018
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.017
dna metabolic process GO:0006259 303 0.017
action potential GO:0001508 78 0.017
multicellular organism growth GO:0035264 161 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
nucleotide metabolic process GO:0009117 332 0.017
leukocyte mediated immunity GO:0002443 174 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
skeletal system development GO:0001501 356 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.017
positive regulation of cellular amine metabolic process GO:0033240 5 0.017
cognition GO:0050890 149 0.017
cardiac muscle cell contraction GO:0086003 7 0.016
lymphocyte mediated immunity GO:0002449 139 0.016
detection of stimulus GO:0051606 84 0.016
meiotic cell cycle GO:0051321 122 0.016
lipid biosynthetic process GO:0008610 179 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
regulation of transmembrane transport GO:0034762 128 0.016
response to protozoan GO:0001562 28 0.016
sequestering of metal ion GO:0051238 19 0.016
dna repair GO:0006281 107 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
multicellular organismal signaling GO:0035637 91 0.016
regulation of binding GO:0051098 111 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
cellular component assembly involved in morphogenesis GO:0010927 139 0.016
organic acid biosynthetic process GO:0016053 86 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.016
regulation of cellular ketone metabolic process GO:0010565 66 0.016
innate immune response GO:0045087 157 0.015
regulation of transferase activity GO:0051338 263 0.015
lymphocyte homeostasis GO:0002260 64 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
cellular transition metal ion homeostasis GO:0046916 32 0.015
translation GO:0006412 93 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
apoptotic signaling pathway GO:0097190 306 0.015
protein ubiquitination GO:0016567 171 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
cellular protein complex assembly GO:0043623 116 0.015
tissue homeostasis GO:0001894 115 0.015
striated muscle tissue development GO:0014706 293 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
cellular lipid metabolic process GO:0044255 323 0.015
endoplasmic reticulum to cytosol transport GO:1903513 12 0.015
response to oxygen levels GO:0070482 62 0.015
erythrocyte maturation GO:0043249 6 0.014
respiratory burst GO:0045730 8 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.014
regulation of cysteine type endopeptidase activity GO:2000116 65 0.014
copper ion transport GO:0006825 10 0.014
wound healing GO:0042060 157 0.014
sequestering of calcium ion GO:0051208 18 0.014
regulation of cell cycle GO:0051726 281 0.014
positive regulation of cytokine production GO:0001819 174 0.014
wnt signaling pathway GO:0016055 188 0.014
positive regulation of interferon gamma production GO:0032729 39 0.014
regulation of mrna stability GO:0043488 23 0.014
response to lipopolysaccharide GO:0032496 128 0.014
nitrogen compound transport GO:0071705 271 0.014
regulation of endocytosis GO:0030100 69 0.014
negative regulation of protein modification process GO:0031400 163 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
response to oxidative stress GO:0006979 123 0.014
regulation of protein localization GO:0032880 231 0.014
regulation of kinase activity GO:0043549 249 0.014
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.014
phospholipid metabolic process GO:0006644 87 0.014
macromolecule methylation GO:0043414 120 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
defense response to bacterium GO:0042742 119 0.014
regulation of protein kinase activity GO:0045859 232 0.014
protein localization to membrane GO:0072657 108 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
positive regulation of phagocytosis GO:0050766 26 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
regulation of t cell activation GO:0050863 170 0.013
heterocycle catabolic process GO:0046700 280 0.013
regulation of cellular amine metabolic process GO:0033238 20 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
anatomical structure homeostasis GO:0060249 145 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
regulation of homeostatic process GO:0032844 182 0.013
nucleoside phosphate metabolic process GO:0006753 338 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
regulation of phagocytosis GO:0050764 33 0.013
sa node cell action potential GO:0086015 4 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
carbohydrate metabolic process GO:0005975 230 0.013
negative regulation of protein activation cascade GO:2000258 3 0.013
negative regulation of homeostatic process GO:0032845 71 0.013
purine nucleotide metabolic process GO:0006163 302 0.013
positive regulation of cell death GO:0010942 224 0.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.013
interferon gamma production GO:0032609 67 0.013
regulation of protein binding GO:0043393 60 0.013
positive regulation of t cell activation GO:0050870 101 0.013
potassium ion transmembrane transport GO:0071805 43 0.012
renal system development GO:0072001 225 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
regulation of leukocyte proliferation GO:0070663 121 0.012
regulation of protein processing GO:0070613 96 0.012
chromatin organization GO:0006325 206 0.012
cell activation involved in immune response GO:0002263 126 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
activation of immune response GO:0002253 138 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
regulation of mapk cascade GO:0043408 248 0.012
regulation of intracellular ph GO:0051453 11 0.012
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 10 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
positive regulation of transferase activity GO:0051347 167 0.012
gland development GO:0048732 330 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
adult behavior GO:0030534 135 0.012
leukocyte differentiation GO:0002521 342 0.012
regulation of protein stability GO:0031647 52 0.012
methylation GO:0032259 134 0.012
digestive tract development GO:0048565 190 0.012
cellular response to oxidative stress GO:0034599 76 0.012
negative regulation of immune system process GO:0002683 209 0.012
transition metal ion transport GO:0000041 38 0.012
nucleobase containing small molecule metabolic process GO:0055086 352 0.011
neuron death GO:0070997 154 0.011
monovalent inorganic cation homeostasis GO:0055067 33 0.011
mitotic nuclear division GO:0007067 48 0.011
positive regulation of potassium ion transmembrane transport GO:1901381 3 0.011
positive regulation of binding GO:0051099 49 0.011
muscle cell differentiation GO:0042692 261 0.011
cellular chemical homeostasis GO:0055082 215 0.011
cellular nitrogen compound catabolic process GO:0044270 280 0.011
response to light stimulus GO:0009416 135 0.011
regulation of ion transport GO:0043269 215 0.011
synaptic transmission GO:0007268 329 0.011
mrna metabolic process GO:0016071 84 0.011
rna processing GO:0006396 105 0.011
nucleoside metabolic process GO:0009116 246 0.011
ph reduction GO:0045851 8 0.011
interleukin 2 production GO:0032623 33 0.011
negative regulation of molecular function GO:0044092 258 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
synapse organization GO:0050808 125 0.011
negative regulation of organelle organization GO:0010639 90 0.011
response to inorganic substance GO:0010035 96 0.011
germ cell development GO:0007281 185 0.011
protein localization to plasma membrane GO:0072659 57 0.011
nucleotide catabolic process GO:0009166 217 0.011
adaptive immune response GO:0002250 155 0.011
nucleoside catabolic process GO:0009164 206 0.011
regulation of calcium ion transmembrane transport GO:1903169 20 0.011
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.011
striated muscle cell development GO:0055002 125 0.011
macrophage activation GO:0042116 27 0.011
kidney development GO:0001822 213 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
myosin filament organization GO:0031033 3 0.011
protein polymerization GO:0051258 57 0.011
positive regulation of protein binding GO:0032092 29 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
myosin filament assembly GO:0031034 2 0.010
antigen processing and presentation GO:0019882 47 0.010
proton transport GO:0015992 35 0.010
embryonic organ morphogenesis GO:0048562 276 0.010
lymphocyte activation involved in immune response GO:0002285 93 0.010
purine nucleoside catabolic process GO:0006152 205 0.010
fertilization GO:0009566 127 0.010
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010
dephosphorylation GO:0016311 129 0.010
cytokine production involved in immune response GO:0002367 34 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
regulation of protein maturation GO:1903317 96 0.010
organophosphate catabolic process GO:0046434 232 0.010
sterol metabolic process GO:0016125 58 0.010
intracellular mrna localization GO:0008298 4 0.010
regulation of calcium ion transport into cytosol GO:0010522 31 0.010
male anatomical structure morphogenesis GO:0090598 4 0.010

Uros disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.309
disease of anatomical entity DOID:7 0 0.309
anemia DOID:2355 0 0.309
hematopoietic system disease DOID:74 0 0.309
disease of metabolism DOID:0014667 0 0.085
inherited metabolic disorder DOID:655 0 0.085
nervous system disease DOID:863 0 0.020
central nervous system disease DOID:331 0 0.019
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
neurodegenerative disease DOID:1289 0 0.012
normocytic anemia DOID:720 0 0.010