Mus musculus

38 known processes

Vamp8

vesicle-associated membrane protein 8

(Aliases: AU041171,Edb,endobrevin)

Vamp8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 399 0.182
ion transmembrane transport GO:0034220 361 0.155
Human
cation homeostasis GO:0055080 212 0.124
protein maturation GO:0051604 176 0.117
calcium ion transport GO:0006816 159 0.113
regulation of ion transport GO:0043269 215 0.080
transmembrane transport GO:0055085 412 0.077
Human
response to inorganic substance GO:0010035 96 0.075
oxidation reduction process GO:0055114 342 0.066
membrane organization GO:0061024 245 0.063
regulation of hydrolase activity GO:0051336 246 0.060
regulation of proteolysis GO:0030162 164 0.060
inorganic ion transmembrane transport GO:0098660 234 0.058
Human
divalent metal ion transport GO:0070838 172 0.058
positive regulation of hydrolase activity GO:0051345 148 0.055
positive regulation of secretion GO:0051047 130 0.054
peptide secretion GO:0002790 114 0.052
cellular homeostasis GO:0019725 240 0.047
cellular ion homeostasis GO:0006873 165 0.047
actin cytoskeleton organization GO:0030036 220 0.045
nucleotide metabolic process GO:0009117 332 0.044
inorganic cation transmembrane transport GO:0098662 207 0.043
regulation of peptidase activity GO:0052547 96 0.043
divalent inorganic cation transport GO:0072511 178 0.042
cation transmembrane transport GO:0098655 266 0.041
nitrogen compound transport GO:0071705 271 0.040
interleukin 1 alpha secretion GO:0050703 3 0.039
cellular amino acid metabolic process GO:0006520 103 0.038
amide transport GO:0042886 138 0.038
cellular chemical homeostasis GO:0055082 215 0.038
regulation of protein maturation GO:1903317 96 0.038
regulation of ion transmembrane transport GO:0034765 119 0.038
regulation of transmembrane transport GO:0034762 128 0.037
positive regulation of cell death GO:0010942 224 0.037
vesicle organization GO:0016050 60 0.037
protein processing GO:0016485 163 0.036
water soluble vitamin biosynthetic process GO:0042364 3 0.035
positive regulation of necrotic cell death GO:0010940 1 0.035
cellular divalent inorganic cation homeostasis GO:0072503 127 0.034
immune effector process GO:0002252 321 0.033
organic cyclic compound catabolic process GO:1901361 295 0.032
negative regulation of cell proliferation GO:0008285 296 0.031
negative regulation of cellular protein metabolic process GO:0032269 247 0.030
cytoplasmic transport GO:0016482 234 0.030
regulation of ion transmembrane transporter activity GO:0032412 54 0.030
regulation of voltage gated calcium channel activity GO:1901385 4 0.030
response to metal ion GO:0010038 47 0.029
blood vessel morphogenesis GO:0048514 285 0.029
response to calcium ion GO:0051592 20 0.028
regulation of intracellular transport GO:0032386 159 0.028
monosaccharide metabolic process GO:0005996 106 0.027
negative regulation of protein metabolic process GO:0051248 282 0.027
metal ion homeostasis GO:0055065 189 0.027
t cell activation GO:0042110 289 0.026
regulation of metal ion transport GO:0010959 106 0.026
cellular metal ion homeostasis GO:0006875 151 0.025
exocytosis GO:0006887 121 0.025
regulation of synaptic plasticity GO:0048167 87 0.025
negative regulation of molecular function GO:0044092 258 0.024
carbohydrate metabolic process GO:0005975 230 0.023
peptide transport GO:0015833 133 0.023
cellular ketone metabolic process GO:0042180 84 0.023
negative regulation of protein processing GO:0010955 79 0.023
cellular protein complex assembly GO:0043623 116 0.022
innate immune response GO:0045087 157 0.022
regulation of hormone levels GO:0010817 211 0.022
myosin filament organization GO:0031033 3 0.022
regulation of peptide secretion GO:0002791 77 0.022
hexose metabolic process GO:0019318 98 0.021
defense response to gram positive bacterium GO:0050830 50 0.021
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
maintenance of location GO:0051235 89 0.021
sulfur compound metabolic process GO:0006790 100 0.020
endomembrane system organization GO:0010256 147 0.020
Human
inflammatory response GO:0006954 244 0.020
apoptotic signaling pathway GO:0097190 306 0.019
macromolecule catabolic process GO:0009057 281 0.019
positive regulation of endopeptidase activity GO:0010950 43 0.019
regulation of secretion by cell GO:1903530 249 0.019
Human
nucleoside phosphate metabolic process GO:0006753 338 0.019
protein oligomerization GO:0051259 67 0.019
response to acid chemical GO:0001101 111 0.019
negative regulation of proteolysis GO:0045861 74 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
microtubule based process GO:0007017 236 0.019
ossification GO:0001503 216 0.019
anion transport GO:0006820 177 0.018
Human
cognition GO:0050890 149 0.018
lymphocyte proliferation GO:0046651 164 0.018
regulation of endopeptidase activity GO:0052548 89 0.018
galactose metabolic process GO:0006012 4 0.018
striated muscle myosin thick filament assembly GO:0071688 1 0.017
cytosolic calcium ion homeostasis GO:0051480 70 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
regulation of secretion GO:0051046 274 0.017
Human
regulation of cellular amino acid metabolic process GO:0006521 5 0.017
cell fate commitment GO:0045165 210 0.017
central nervous system morphogenesis GO:0021551 2 0.017
positive regulation of mitochondrial calcium ion concentration GO:0051561 3 0.017
fucose metabolic process GO:0006004 1 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
positive regulation of ion transport GO:0043270 65 0.017
regulation of peptide transport GO:0090087 91 0.016
cell killing GO:0001906 67 0.016
response to organic cyclic compound GO:0014070 198 0.016
regulation of protein localization GO:0032880 231 0.016
Human
multi multicellular organism process GO:0044706 109 0.016
myosin filament assembly GO:0031034 2 0.016
interspecies interaction between organisms GO:0044419 83 0.016
Human
cellular response to glucose stimulus GO:0071333 45 0.016
copper ion transport GO:0006825 10 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
endoplasmic reticulum tubular network organization GO:0071786 1 0.016
defense response to bacterium GO:0042742 119 0.015
regulation of kinase activity GO:0043549 249 0.015
male gamete generation GO:0048232 285 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
regulation of ossification GO:0030278 112 0.015
cellular response to acid chemical GO:0071229 68 0.015
bone development GO:0060348 120 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
positive regulation of peptidase activity GO:0010952 49 0.015
carbohydrate homeostasis GO:0033500 128 0.015
regulation of membrane potential GO:0042391 192 0.015
dna metabolic process GO:0006259 303 0.015
homeostasis of number of cells GO:0048872 210 0.015
intracellular protein transport GO:0006886 204 0.015
regulation of cellular ketone metabolic process GO:0010565 66 0.015
cellular amine metabolic process GO:0044106 44 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
mapk cascade GO:0000165 281 0.014
regulation of homeostatic process GO:0032844 182 0.014
synaptic transmission GO:0007268 329 0.014
regulation of response to wounding GO:1903034 189 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
regulation of binding GO:0051098 111 0.014
glucose homeostasis GO:0042593 128 0.014
response to lipopolysaccharide GO:0032496 128 0.014
hormone metabolic process GO:0042445 86 0.013
circulatory system process GO:0003013 197 0.013
notch signaling pathway GO:0007219 71 0.013
striated muscle cell development GO:0055002 125 0.013
regulation of neuron differentiation GO:0045664 281 0.013
muscle cell differentiation GO:0042692 261 0.013
lateral inhibition GO:0046331 1 0.013
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
calcium ion transmembrane transport GO:0070588 85 0.013
regulation of intracellular protein transport GO:0033157 82 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
regulation of integrin biosynthetic process GO:0045113 1 0.013
kidney development GO:0001822 213 0.013
coenzyme metabolic process GO:0006732 52 0.013
spermatogenesis GO:0007283 284 0.013
regulation of protein processing GO:0070613 96 0.013
neuron death GO:0070997 154 0.013
ameboidal type cell migration GO:0001667 128 0.013
pharynx development GO:0060465 1 0.013
single organism cell adhesion GO:0098602 156 0.013
hexose catabolic process GO:0019320 3 0.012
negative regulation of hydrolase activity GO:0051346 71 0.012
regulation of calcium ion transport GO:0051924 69 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
nucleobase containing small molecule metabolic process GO:0055086 352 0.012
defense response to other organism GO:0098542 197 0.012
nuclear import GO:0051170 95 0.012
leukocyte mediated immunity GO:0002443 174 0.012
extracellular structure organization GO:0043062 148 0.012
regulation of protein kinase activity GO:0045859 232 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
regulation of cell projection organization GO:0031344 206 0.012
i kappab kinase nf kappab signaling GO:0007249 85 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
heterocycle catabolic process GO:0046700 280 0.012
actin polymerization or depolymerization GO:0008154 54 0.012
bile acid secretion GO:0032782 2 0.012
hormone secretion GO:0046879 128 0.012
regulation of mapk cascade GO:0043408 248 0.012
plasma membrane organization GO:0007009 90 0.012
Human
ketone catabolic process GO:0042182 3 0.012
fat cell differentiation GO:0045444 160 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
sensory perception GO:0007600 245 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
regulation of neuron projection development GO:0010975 169 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
chemotaxis GO:0006935 247 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
nucleotide catabolic process GO:0009166 217 0.011
sequestering of calcium ion GO:0051208 18 0.011
adaptive immune response GO:0002250 155 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
cellular response to lipid GO:0071396 145 0.011
leukocyte chemotaxis GO:0030595 69 0.011
cytosolic calcium ion transport GO:0060401 48 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
negative regulation of immune system process GO:0002683 209 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.011
Human
muscle cell development GO:0055001 133 0.011
maintenance of apical basal cell polarity GO:0035090 3 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
cellular response to monosaccharide stimulus GO:0071326 47 0.011
aromatic compound catabolic process GO:0019439 286 0.011
t cell mediated immunity GO:0002456 50 0.011
negative regulation of protein maturation GO:1903318 79 0.011
transition metal ion homeostasis GO:0055076 54 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.011
lipid localization GO:0010876 126 0.011
amine metabolic process GO:0009308 45 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
sodium ion transmembrane transport GO:0035725 49 0.011
leukocyte differentiation GO:0002521 342 0.011
skin development GO:0043588 220 0.011
cytokine secretion GO:0050663 72 0.011
cytokine production GO:0001816 319 0.011
regulation of osteoblast differentiation GO:0045667 67 0.011
multicellular organismal signaling GO:0035637 91 0.011
integrin biosynthetic process GO:0045112 1 0.010
negative regulation of neuron death GO:1901215 98 0.010
purine nucleoside metabolic process GO:0042278 241 0.010
wound healing GO:0042060 157 0.010
positive regulation of apoptotic process GO:0043065 217 0.010
regulation of transferase activity GO:0051338 263 0.010
regulation of cellular amine metabolic process GO:0033238 20 0.010
respiratory tube development GO:0030323 167 0.010
protein secretion GO:0009306 111 0.010
autophagy GO:0006914 45 0.010
Human
developmental maturation GO:0021700 193 0.010
regulation of defense response GO:0031347 233 0.010
organelle fission GO:0048285 170 0.010
sequestering of metal ion GO:0051238 19 0.010
positive regulation of homeostatic process GO:0032846 64 0.010
cofactor metabolic process GO:0051186 80 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010

Vamp8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.037
disease of anatomical entity DOID:7 0 0.037
disease of metabolism DOID:0014667 0 0.035
lysosomal storage disease DOID:3211 0 0.027
inherited metabolic disorder DOID:655 0 0.027
nervous system disease DOID:863 0 0.025
epilepsy syndrome DOID:1826 0 0.020
central nervous system disease DOID:331 0 0.020
brain disease DOID:936 0 0.020
electroclinical syndrome DOID:0050701 0 0.020
integumentary system disease DOID:16 0 0.014
variable age at onset electroclinical syndrome DOID:0050706 0 0.013
progressive myoclonus epilepsy DOID:891 0 0.011