Mus musculus

0 known processes

Vars

valyl-tRNA synthetase

(Aliases: D17H6S56E,Bat6,G7a,Vars2)

Vars biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic retina morphogenesis in camera type eye GO:0060060 3 0.484
purine nucleoside catabolic process GO:0006152 205 0.475
organic cyclic compound catabolic process GO:1901361 295 0.336
nucleoside triphosphate metabolic process GO:0009141 230 0.291
nucleoside metabolic process GO:0009116 246 0.262
purine ribonucleoside catabolic process GO:0046130 205 0.257
regulation of hydrolase activity GO:0051336 246 0.247
heterocycle catabolic process GO:0046700 280 0.226
glycosyl compound metabolic process GO:1901657 246 0.223
ribose phosphate metabolic process GO:0019693 291 0.211
dna metabolic process GO:0006259 303 0.199
purine nucleoside triphosphate metabolic process GO:0009144 226 0.182
purine containing compound metabolic process GO:0072521 311 0.172
organonitrogen compound catabolic process GO:1901565 264 0.167
aromatic compound catabolic process GO:0019439 286 0.164
purine nucleoside metabolic process GO:0042278 241 0.151
ribonucleotide catabolic process GO:0009261 208 0.140
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.133
regulation of cytoplasmic transport GO:1903649 112 0.128
nls bearing protein import into nucleus GO:0006607 2 0.126
carbohydrate derivative catabolic process GO:1901136 231 0.125
purine containing compound catabolic process GO:0072523 213 0.119
nucleoside catabolic process GO:0009164 206 0.118
nucleoside triphosphate catabolic process GO:0009143 205 0.115
purine ribonucleotide metabolic process GO:0009150 290 0.113
purine ribonucleoside metabolic process GO:0046128 241 0.105
glycosyl compound catabolic process GO:1901658 206 0.104
nucleobase containing small molecule metabolic process GO:0055086 352 0.103
purine ribonucleotide catabolic process GO:0009154 208 0.103
chromatin organization GO:0006325 206 0.095
cellular nitrogen compound catabolic process GO:0044270 280 0.095
ribonucleoside triphosphate metabolic process GO:0009199 220 0.092
transmembrane transport GO:0055085 412 0.087
protein processing GO:0016485 163 0.086
organophosphate catabolic process GO:0046434 232 0.083
regulation of nucleotide catabolic process GO:0030811 122 0.082
dna methylation GO:0006306 43 0.081
maturation of 5 8s rrna GO:0000460 1 0.080
ribonucleotide metabolic process GO:0009259 291 0.078
atp metabolic process GO:0046034 75 0.076
purine nucleotide catabolic process GO:0006195 211 0.075
cellular amino acid metabolic process GO:0006520 103 0.074
regulation of cell cycle GO:0051726 281 0.073
ribonucleoside catabolic process GO:0042454 206 0.072
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.071
cellular amine metabolic process GO:0044106 44 0.071
nuclear transport GO:0051169 139 0.069
nucleoside phosphate metabolic process GO:0006753 338 0.069
regulation of protein localization GO:0032880 231 0.065
single organism nuclear import GO:1902593 95 0.065
protein import GO:0017038 101 0.065
regulation of nucleotide metabolic process GO:0006140 169 0.064
cellular ketone metabolic process GO:0042180 84 0.064
nucleoside monophosphate metabolic process GO:0009123 85 0.063
pyrimidine nucleobase metabolic process GO:0006206 3 0.061
ribonucleoside metabolic process GO:0009119 245 0.061
negative regulation of molecular function GO:0044092 258 0.060
purine nucleoside triphosphate catabolic process GO:0009146 203 0.060
microtubule cytoskeleton organization GO:0000226 157 0.057
macromolecule methylation GO:0043414 120 0.057
mitotic cell cycle GO:0000278 195 0.057
multicellular organism growth GO:0035264 161 0.057
posttranscriptional regulation of gene expression GO:0010608 155 0.055
microtubule based process GO:0007017 236 0.055
mitochondrion organization GO:0007005 134 0.054
intracellular protein transport GO:0006886 204 0.052
peptidyl amino acid modification GO:0018193 336 0.051
nuclear import GO:0051170 95 0.050
protein maturation GO:0051604 176 0.050
protein localization to organelle GO:0033365 185 0.048
macromolecule catabolic process GO:0009057 281 0.046
negative regulation of cellular protein metabolic process GO:0032269 247 0.046
regulation of cellular catabolic process GO:0031329 242 0.046
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.045
metal ion homeostasis GO:0055065 189 0.045
peptide metabolic process GO:0006518 46 0.045
regulation of cell motility GO:2000145 236 0.043
leukocyte differentiation GO:0002521 342 0.043
negative regulation of proteolysis GO:0045861 74 0.043
nucleotide catabolic process GO:0009166 217 0.043
gene silencing GO:0016458 38 0.042
nucleotide metabolic process GO:0009117 332 0.042
ion transmembrane transport GO:0034220 361 0.042
modification dependent macromolecule catabolic process GO:0043632 133 0.041
photoreceptor cell morphogenesis GO:0008594 3 0.041
regulation of protein targeting GO:1903533 61 0.041
apoptotic signaling pathway GO:0097190 306 0.041
cation homeostasis GO:0055080 212 0.040
nucleoside phosphate catabolic process GO:1901292 222 0.039
response to amino acid GO:0043200 37 0.039
development of primary sexual characteristics GO:0045137 143 0.039
protein import into nucleus GO:0006606 95 0.038
response to endoplasmic reticulum stress GO:0034976 53 0.037
stem cell differentiation GO:0048863 268 0.037
negative regulation of cellular component organization GO:0051129 194 0.037
regulation of cell cycle process GO:0010564 160 0.037
ribonucleoside triphosphate catabolic process GO:0009203 199 0.036
regulation of cell cycle checkpoint GO:1901976 9 0.036
cytoplasmic transport GO:0016482 234 0.035
purine nucleoside monophosphate catabolic process GO:0009128 58 0.035
purine nucleotide metabolic process GO:0006163 302 0.034
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.034
trna wobble uridine modification GO:0002098 2 0.034
posttranscriptional gene silencing GO:0016441 10 0.034
cellular ion homeostasis GO:0006873 165 0.033
cytoplasmic translational initiation GO:0002183 3 0.033
trna modification GO:0006400 9 0.033
trna processing GO:0008033 11 0.033
rna interference GO:0016246 2 0.033
negative regulation of protein metabolic process GO:0051248 282 0.033
regulation of cellular ketone metabolic process GO:0010565 66 0.033
establishment of protein localization to organelle GO:0072594 118 0.032
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.032
positive regulation of hydrolase activity GO:0051345 148 0.032
regulation of purine nucleotide catabolic process GO:0033121 122 0.032
positive regulation of gtpase activity GO:0043547 85 0.031
regulation of nucleoside metabolic process GO:0009118 130 0.031
cellular amide metabolic process GO:0043603 58 0.031
regulation of intracellular transport GO:0032386 159 0.031
organonitrogen compound biosynthetic process GO:1901566 192 0.031
gonad development GO:0008406 141 0.030
methylation GO:0032259 134 0.030
spermatogenesis GO:0007283 284 0.030
response to acid chemical GO:0001101 111 0.029
peptidyl lysine modification GO:0018205 77 0.029
chromosome organization involved in meiosis GO:0070192 39 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.029
protein targeting GO:0006605 143 0.029
positive regulation of chromosome segregation GO:0051984 4 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
rna processing GO:0006396 105 0.029
divalent inorganic cation homeostasis GO:0072507 138 0.028
ribonucleoside monophosphate catabolic process GO:0009158 57 0.028
regulation of protein import into nucleus GO:0042306 52 0.028
endonucleolytic cleavage involved in rrna processing GO:0000478 1 0.028
regulation of ion transmembrane transport GO:0034765 119 0.028
nucleocytoplasmic transport GO:0006913 139 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
guanosine containing compound metabolic process GO:1901068 144 0.028
translation GO:0006412 93 0.028
negative regulation of purine nucleotide catabolic process GO:0033122 9 0.027
positive regulation of dna repair GO:0045739 3 0.027
ossification GO:0001503 216 0.027
guanosine containing compound catabolic process GO:1901069 144 0.026
endocytosis GO:0006897 168 0.026
response to organic cyclic compound GO:0014070 198 0.026
covalent chromatin modification GO:0016569 163 0.026
regulation of cell cycle g2 m phase transition GO:1902749 10 0.026
atp catabolic process GO:0006200 55 0.026
dna repair GO:0006281 107 0.025
maintenance of location GO:0051235 89 0.025
calcium ion homeostasis GO:0055074 127 0.025
cell substrate adhesion GO:0031589 130 0.025
cellular homeostasis GO:0019725 240 0.025
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.025
dna modification GO:0006304 50 0.025
rhythmic process GO:0048511 174 0.025
amine metabolic process GO:0009308 45 0.025
regulation of protein maturation GO:1903317 96 0.024
vitamin d receptor signaling pathway GO:0070561 2 0.024
immune effector process GO:0002252 321 0.024
gland development GO:0048732 330 0.024
cell cycle checkpoint GO:0000075 47 0.024
positive regulation of intracellular transport GO:0032388 70 0.024
regulation of organelle organization GO:0033043 289 0.024
positive regulation of protein modification process GO:0031401 299 0.023
meiosis i GO:0007127 60 0.023
negative regulation of cell substrate adhesion GO:0010812 16 0.023
negative regulation of cellular catabolic process GO:0031330 47 0.023
dna recombination GO:0006310 92 0.023
metencephalon development GO:0022037 89 0.023
sensory organ morphogenesis GO:0090596 242 0.023
regulation of multi organism process GO:0043900 111 0.023
negative regulation of protein modification process GO:0031400 163 0.023
meiotic cell cycle GO:0051321 122 0.022
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.022
regulation of translation GO:0006417 71 0.022
regulation of ran gtpase activity GO:0032316 3 0.022
synapsis GO:0007129 34 0.022
negative regulation of cell cycle GO:0045786 123 0.022
rna catabolic process GO:0006401 29 0.022
mesenchymal cell development GO:0014031 93 0.022
positive regulation of nucleotide metabolic process GO:0045981 114 0.022
positive regulation of gtp catabolic process GO:0033126 85 0.021
cognition GO:0050890 149 0.021
synaptonemal complex organization GO:0070193 15 0.021
carbohydrate metabolic process GO:0005975 230 0.021
nuclear division GO:0000280 158 0.021
cellular response to cytokine stimulus GO:0071345 189 0.021
intracellular receptor signaling pathway GO:0030522 74 0.020
hexose metabolic process GO:0019318 98 0.020
ribonucleoside monophosphate metabolic process GO:0009161 80 0.020
purine nucleoside monophosphate metabolic process GO:0009126 81 0.020
locomotory behavior GO:0007626 195 0.020
positive regulation of dna templated transcription elongation GO:0032786 2 0.020
cellular carbohydrate metabolic process GO:0044262 119 0.020
negative regulation of hydrolase activity GO:0051346 71 0.020
positive regulation of growth GO:0045927 104 0.019
regulation of peptidase activity GO:0052547 96 0.019
primary neural tube formation GO:0014020 95 0.019
cell junction organization GO:0034330 77 0.019
regulation of mitotic cell cycle phase transition GO:1901990 73 0.019
negative regulation of protein maturation GO:1903318 79 0.019
regulation of nuclear division GO:0051783 56 0.019
cleavage involved in rrna processing GO:0000469 1 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.019
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.019
regulation of ion transport GO:0043269 215 0.019
nucleobase biosynthetic process GO:0046112 3 0.018
regulation of cellular amine metabolic process GO:0033238 20 0.018
regulation of dna demethylation GO:1901535 2 0.018
histone deubiquitination GO:0016578 2 0.018
receptor mediated endocytosis GO:0006898 51 0.018
recombinational repair GO:0000725 21 0.018
response to light stimulus GO:0009416 135 0.018
response to organonitrogen compound GO:0010243 246 0.018
positive regulation of antimicrobial peptide production GO:0002225 1 0.017
protein localization to nucleus GO:0034504 121 0.017
positive regulation of cellular catabolic process GO:0031331 148 0.017
positive regulation of cell death GO:0010942 224 0.017
glial cell development GO:0021782 54 0.017
cation transport GO:0006812 399 0.017
cell junction assembly GO:0034329 52 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
camera type eye development GO:0043010 266 0.017
protein catabolic process GO:0030163 221 0.017
regulation of glucose metabolic process GO:0010906 60 0.017
learning or memory GO:0007611 148 0.017
peptidyl serine modification GO:0018209 83 0.017
chemotaxis GO:0006935 247 0.017
response to reactive oxygen species GO:0000302 56 0.017
defense response to bacterium GO:0042742 119 0.017
ncrna processing GO:0034470 26 0.016
negative regulation of apoptotic signaling pathway GO:2001234 104 0.016
mesenchyme development GO:0060485 152 0.016
regulation of cytoskeleton organization GO:0051493 122 0.016
positive regulation of nucleotide catabolic process GO:0030813 88 0.016
negative regulation of protein processing GO:0010955 79 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
regulation of transporter activity GO:0032409 57 0.016
regulation of cellular amino acid metabolic process GO:0006521 5 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
t cell differentiation GO:0030217 174 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
gtp catabolic process GO:0006184 143 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
tube closure GO:0060606 91 0.015
regulation of endopeptidase activity GO:0052548 89 0.015
response to inorganic substance GO:0010035 96 0.015
negative regulation of nucleoside metabolic process GO:0045978 11 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
positive regulation of ran gtpase activity GO:0032853 3 0.015
cellular response to lipid GO:0071396 145 0.015
hyaluronan metabolic process GO:0030212 4 0.015
response to oxygen levels GO:0070482 62 0.015
regulation of attachment of spindle microtubules to kinetochore GO:0051988 3 0.015
protein ubiquitination GO:0016567 171 0.015
regulation of the force of heart contraction GO:0002026 17 0.015
cell cycle g2 m phase transition GO:0044839 20 0.015
regulation of metal ion transport GO:0010959 106 0.015
response to oxidative stress GO:0006979 123 0.014
monosaccharide metabolic process GO:0005996 106 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.014
response to lipopolysaccharide GO:0032496 128 0.014
molting cycle GO:0042303 90 0.014
desensitization of g protein coupled receptor protein signaling pathway GO:0002029 5 0.014
regulation of ran protein signal transduction GO:0032015 3 0.014
embryonic placenta development GO:0001892 98 0.014
histone methylation GO:0016571 71 0.014
execution phase of apoptosis GO:0097194 19 0.014
meiotic nuclear division GO:0007126 115 0.014
dephosphorylation GO:0016311 129 0.014
rna modification GO:0009451 20 0.014
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 1 0.014
t cell activation GO:0042110 289 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
cellular chemical homeostasis GO:0055082 215 0.014
mrna metabolic process GO:0016071 84 0.014
organelle fission GO:0048285 170 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
regulation of cell activation GO:0050865 289 0.014
nitrogen compound transport GO:0071705 271 0.014
innate immune response GO:0045087 157 0.014
regulation of carbohydrate metabolic process GO:0006109 75 0.013
sensory perception GO:0007600 245 0.013
histone h4 k16 acetylation GO:0043984 3 0.013
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.013
regulation of neuron differentiation GO:0045664 281 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
ovarian follicle development GO:0001541 40 0.013
regulation of proteolysis GO:0030162 164 0.013
iron sulfur cluster assembly GO:0016226 3 0.013
regulation of protein processing GO:0070613 96 0.013
viral process GO:0016032 41 0.013
response to hypoxia GO:0001666 58 0.013
skeletal system development GO:0001501 356 0.013
positive regulation of cell cycle process GO:0090068 61 0.013
germ cell development GO:0007281 185 0.013
multi multicellular organism process GO:0044706 109 0.013
dna alkylation GO:0006305 43 0.013
digestive tract development GO:0048565 190 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
dendrite development GO:0016358 115 0.013
cell growth GO:0016049 130 0.013
negative regulation of cell development GO:0010721 169 0.013
regulation of mitotic cell cycle GO:0007346 126 0.012
gtp metabolic process GO:0046039 144 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
regulation of adherens junction organization GO:1903391 12 0.012
endomembrane system organization GO:0010256 147 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
regulation of neuron projection development GO:0010975 169 0.012
hindbrain development GO:0030902 128 0.012
regulation of transmembrane transport GO:0034762 128 0.012
regulation of cell division GO:0051302 76 0.012
lipid homeostasis GO:0055088 63 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
carbohydrate biosynthetic process GO:0016051 74 0.012
photoreceptor cell differentiation GO:0046530 52 0.012
pharynx development GO:0060465 1 0.012
mammary gland morphogenesis GO:0060443 54 0.012
fertilization GO:0009566 127 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
hatching GO:0035188 4 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
cell adhesion GO:0007155 329 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.011
negative regulation of kinase activity GO:0033673 81 0.011
protein alkylation GO:0008213 81 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
divalent inorganic cation transport GO:0072511 178 0.011
skin development GO:0043588 220 0.011
regulation of carbohydrate biosynthetic process GO:0043255 40 0.011
viral life cycle GO:0019058 36 0.011
neural tube development GO:0021915 160 0.011
positive regulation of chromosome organization GO:2001252 33 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
protein methylation GO:0006479 81 0.011
regulation of protein kinase activity GO:0045859 232 0.011
placenta development GO:0001890 140 0.011
antimicrobial peptide biosynthetic process GO:0002777 2 0.011
nuclear export GO:0051168 34 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
negative regulation of organelle organization GO:0010639 90 0.011
transition metal ion homeostasis GO:0055076 54 0.011
positive regulation of catecholamine secretion GO:0033605 2 0.010
regulation of cell substrate adhesion GO:0010810 73 0.010
neural crest cell development GO:0014032 48 0.010
regulation of intracellular protein transport GO:0033157 82 0.010
cytokine production GO:0001816 319 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
response to radiation GO:0009314 165 0.010
mitotic cell cycle process GO:1903047 159 0.010
reactive oxygen species metabolic process GO:0072593 84 0.010
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 9 0.010
regulation of protein transport GO:0051223 163 0.010
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.010
regulation of substrate adhesion dependent cell spreading GO:1900024 12 0.010
blood circulation GO:0008015 195 0.010

Vars disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
neuromuscular disease DOID:440 0 0.031
neuropathy DOID:870 0 0.031
gastrointestinal system cancer DOID:3119 0 0.024
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.024
retinal disease DOID:5679 0 0.023
retinal degeneration DOID:8466 0 0.023
sensory system disease DOID:0050155 0 0.023
eye and adnexa disease DOID:1492 0 0.023
eye disease DOID:5614 0 0.023
retinitis pigmentosa DOID:10584 0 0.020
intestinal cancer DOID:10155 0 0.019
large intestine cancer DOID:5672 0 0.015
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.012