Mus musculus

61 known processes

Vdac2

voltage-dependent anion channel 2

(Aliases: Vdac6)

Vdac2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cofactor metabolic process GO:0051186 80 0.617
coenzyme metabolic process GO:0006732 52 0.467
nucleoside phosphate metabolic process GO:0006753 338 0.455
nucleobase containing small molecule metabolic process GO:0055086 352 0.373
oxidation reduction process GO:0055114 342 0.344
ribonucleoside monophosphate metabolic process GO:0009161 80 0.297
thioester biosynthetic process GO:0035384 7 0.296
nucleotide metabolic process GO:0009117 332 0.261
purine ribonucleoside metabolic process GO:0046128 241 0.233
endocytosis GO:0006897 168 0.199
sulfur compound biosynthetic process GO:0044272 37 0.181
nucleoside metabolic process GO:0009116 246 0.172
organophosphate catabolic process GO:0046434 232 0.172
generation of precursor metabolites and energy GO:0006091 103 0.150
atp metabolic process GO:0046034 75 0.149
apoptotic mitochondrial changes GO:0008637 48 0.145
protein processing GO:0016485 163 0.139
purine nucleoside metabolic process GO:0042278 241 0.136
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.135
energy derivation by oxidation of organic compounds GO:0015980 77 0.119
purine nucleoside monophosphate metabolic process GO:0009126 81 0.118
mitochondrion organization GO:0007005 134 0.115
acyl coa biosynthetic process GO:0071616 7 0.112
purine ribonucleotide metabolic process GO:0009150 290 0.112
glycosyl compound catabolic process GO:1901658 206 0.106
glycosyl compound metabolic process GO:1901657 246 0.104
purine nucleoside catabolic process GO:0006152 205 0.101
cytoplasmic transport GO:0016482 234 0.096
purine containing compound metabolic process GO:0072521 311 0.093
sulfur compound metabolic process GO:0006790 100 0.093
ribonucleotide catabolic process GO:0009261 208 0.092
response to oxidative stress GO:0006979 123 0.092
nucleotide catabolic process GO:0009166 217 0.085
acetyl coa biosynthetic process from pyruvate GO:0006086 3 0.084
cation transport GO:0006812 399 0.084
Fly
positive regulation of apoptotic process GO:0043065 217 0.083
coenzyme biosynthetic process GO:0009108 23 0.083
regulation of intracellular transport GO:0032386 159 0.083
ribonucleoside catabolic process GO:0042454 206 0.080
nucleoside monophosphate catabolic process GO:0009125 59 0.079
regulation of proteolysis GO:0030162 164 0.077
purine nucleotide metabolic process GO:0006163 302 0.076
positive regulation of cell death GO:0010942 224 0.076
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.076
organophosphate biosynthetic process GO:0090407 122 0.076
acetyl coa biosynthetic process GO:0006085 5 0.072
aromatic compound catabolic process GO:0019439 286 0.072
positive regulation of hydrolase activity GO:0051345 148 0.068
purine ribonucleoside catabolic process GO:0046130 205 0.068
nucleoside monophosphate metabolic process GO:0009123 85 0.068
ribose phosphate metabolic process GO:0019693 291 0.068
cellular lipid metabolic process GO:0044255 323 0.067
regulation of hydrolase activity GO:0051336 246 0.066
ribonucleotide metabolic process GO:0009259 291 0.065
organonitrogen compound catabolic process GO:1901565 264 0.064
positive regulation of programmed cell death GO:0043068 218 0.063
positive regulation of cellular amine metabolic process GO:0033240 5 0.062
nucleoside catabolic process GO:0009164 206 0.061
germ cell development GO:0007281 185 0.060
organic cyclic compound catabolic process GO:1901361 295 0.060
nucleoside triphosphate catabolic process GO:0009143 205 0.059
intracellular protein transport GO:0006886 204 0.059
heterocycle catabolic process GO:0046700 280 0.058
organic hydroxy compound metabolic process GO:1901615 203 0.058
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.058
cellular nitrogen compound catabolic process GO:0044270 280 0.057
ribonucleoside triphosphate catabolic process GO:0009203 199 0.057
carbohydrate derivative biosynthetic process GO:1901137 183 0.056
regulation of organelle organization GO:0033043 289 0.056
protein modification by small protein conjugation or removal GO:0070647 207 0.055
protein catabolic process GO:0030163 221 0.054
transmembrane transport GO:0055085 412 0.054
Yeast Fly
purine nucleoside monophosphate catabolic process GO:0009128 58 0.054
regulation of endopeptidase activity GO:0052548 89 0.053
ribonucleoside metabolic process GO:0009119 245 0.052
negative regulation of protein metabolic process GO:0051248 282 0.052
metal ion homeostasis GO:0055065 189 0.052
monocarboxylic acid metabolic process GO:0032787 191 0.052
purine nucleotide catabolic process GO:0006195 211 0.051
cation transmembrane transport GO:0098655 266 0.051
Fly
response to inorganic substance GO:0010035 96 0.050
purine nucleoside triphosphate catabolic process GO:0009146 203 0.050
cellular amino acid metabolic process GO:0006520 103 0.049
cofactor transport GO:0051181 4 0.049
purine ribonucleotide catabolic process GO:0009154 208 0.048
purine containing compound catabolic process GO:0072523 213 0.046
nucleoside phosphate biosynthetic process GO:1901293 79 0.044
locomotory behavior GO:0007626 195 0.044
ribonucleoside monophosphate biosynthetic process GO:0009156 9 0.043
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.043
cellular amine metabolic process GO:0044106 44 0.043
membrane organization GO:0061024 245 0.043
sperm motility GO:0030317 47 0.043
spermatogenesis GO:0007283 284 0.042
regulation of peptidase activity GO:0052547 96 0.042
protein maturation GO:0051604 176 0.042
cellular ketone metabolic process GO:0042180 84 0.042
ribonucleoside monophosphate catabolic process GO:0009158 57 0.041
amine metabolic process GO:0009308 45 0.041
cofactor biosynthetic process GO:0051188 41 0.041
cellular protein catabolic process GO:0044257 155 0.041
nitrogen compound transport GO:0071705 271 0.040
Yeast
organic acid biosynthetic process GO:0016053 86 0.039
dephosphorylation GO:0016311 129 0.039
organonitrogen compound biosynthetic process GO:1901566 192 0.038
regulation of cellular amine metabolic process GO:0033238 20 0.038
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.038
carbohydrate metabolic process GO:0005975 230 0.037
positive regulation of proteolysis GO:0045862 85 0.037
protein localization to organelle GO:0033365 185 0.037
pyruvate metabolic process GO:0006090 28 0.036
nicotinamide nucleotide metabolic process GO:0046496 12 0.036
regulation of ion transport GO:0043269 215 0.035
Yeast Fly
microtubule based process GO:0007017 236 0.035
nucleoside phosphate catabolic process GO:1901292 222 0.035
negative regulation of cell proliferation GO:0008285 296 0.035
acyl coa metabolic process GO:0006637 19 0.034
cellular respiration GO:0045333 38 0.034
nucleoside triphosphate metabolic process GO:0009141 230 0.034
pigment metabolic process GO:0042440 32 0.034
regulation of secretion GO:0051046 274 0.033
cellular chemical homeostasis GO:0055082 215 0.033
regulation of protein targeting GO:1903533 61 0.032
oxidoreduction coenzyme metabolic process GO:0006733 16 0.032
purine nucleoside triphosphate metabolic process GO:0009144 226 0.032
lymphocyte proliferation GO:0046651 164 0.032
regulation of cysteine type endopeptidase activity GO:2000116 65 0.032
ras protein signal transduction GO:0007265 77 0.032
lipid biosynthetic process GO:0008610 179 0.031
regulation of cellular ketone metabolic process GO:0010565 66 0.031
positive regulation of protein modification process GO:0031401 299 0.031
mitotic cell cycle GO:0000278 195 0.031
ion transmembrane transport GO:0034220 361 0.031
Yeast Fly
small gtpase mediated signal transduction GO:0007264 97 0.031
negative regulation of cellular protein metabolic process GO:0032269 247 0.030
divalent metal ion transport GO:0070838 172 0.030
ribonucleoside triphosphate metabolic process GO:0009199 220 0.030
inorganic ion transmembrane transport GO:0098660 234 0.030
mitotic cell cycle process GO:1903047 159 0.030
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.030
carbohydrate derivative catabolic process GO:1901136 231 0.029
regulation of protein transport GO:0051223 163 0.029
microtubule cytoskeleton organization GO:0000226 157 0.029
positive regulation of organelle organization GO:0010638 128 0.029
regulation of protein localization GO:0032880 231 0.029
reactive oxygen species metabolic process GO:0072593 84 0.028
small molecule biosynthetic process GO:0044283 132 0.028
cellular divalent inorganic cation homeostasis GO:0072503 127 0.028
cellular ion homeostasis GO:0006873 165 0.028
cell adhesion GO:0007155 329 0.028
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.028
carboxylic acid biosynthetic process GO:0046394 86 0.027
ribonucleotide biosynthetic process GO:0009260 59 0.027
nucleotide biosynthetic process GO:0009165 78 0.026
regulation of mitochondrial fission GO:0090140 3 0.026
acetyl coa metabolic process GO:0006084 8 0.026
cellular amide metabolic process GO:0043603 58 0.026
cellular response to oxidative stress GO:0034599 76 0.026
cellular metal ion homeostasis GO:0006875 151 0.025
cellular response to organonitrogen compound GO:0071417 145 0.025
regulation of intracellular protein transport GO:0033157 82 0.025
inorganic cation transmembrane transport GO:0098662 207 0.025
positive regulation of protein phosphorylation GO:0001934 242 0.025
mitochondrial calcium ion homeostasis GO:0051560 7 0.025
phospholipid metabolic process GO:0006644 87 0.024
response to metal ion GO:0010038 47 0.024
positive regulation of endopeptidase activity GO:0010950 43 0.024
protein targeting GO:0006605 143 0.024
cellular homeostasis GO:0019725 240 0.024
Yeast
modification dependent macromolecule catabolic process GO:0043632 133 0.024
negative regulation of phosphorus metabolic process GO:0010563 184 0.024
regulation of transmembrane transport GO:0034762 128 0.024
Yeast Fly
sequestering of calcium ion GO:0051208 18 0.024
cellular response to dna damage stimulus GO:0006974 207 0.024
regulation of secretion by cell GO:1903530 249 0.023
regulation of cytoplasmic transport GO:1903649 112 0.023
regulation of ion transmembrane transport GO:0034765 119 0.023
Yeast Fly
receptor mediated endocytosis GO:0006898 51 0.023
substantia nigra development GO:0021762 2 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
negative regulation of phosphorylation GO:0042326 166 0.022
response to temperature stimulus GO:0009266 55 0.022
phagocytosis GO:0006909 66 0.022
divalent inorganic cation homeostasis GO:0072507 138 0.022
macromolecule catabolic process GO:0009057 281 0.022
genitalia development GO:0048806 37 0.022
neural tube formation GO:0001841 108 0.022
negative regulation of organelle organization GO:0010639 90 0.021
morphogenesis of embryonic epithelium GO:0016331 159 0.021
calcium ion homeostasis GO:0055074 127 0.021
response to organonitrogen compound GO:0010243 246 0.021
negative regulation of cell development GO:0010721 169 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
atp catabolic process GO:0006200 55 0.020
sperm individualization GO:0007291 1 0.020
response to iron ion GO:0010039 4 0.020
purine containing compound biosynthetic process GO:0072522 70 0.020
positive regulation of peptidase activity GO:0010952 49 0.020
protein localization to mitochondrion GO:0070585 15 0.020
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.020
pyridine containing compound metabolic process GO:0072524 14 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
regulation of protein catabolic process GO:0042176 108 0.020
regulation of membrane potential GO:0042391 192 0.020
positive regulation of protein kinase activity GO:0045860 144 0.020
divalent inorganic cation transport GO:0072511 178 0.019
peptidyl amino acid modification GO:0018193 336 0.019
regulation of protein complex assembly GO:0043254 83 0.019
regulation of cell cycle GO:0051726 281 0.019
nuclear transport GO:0051169 139 0.019
cellular protein complex assembly GO:0043623 116 0.019
protein ubiquitination GO:0016567 171 0.019
regulation of multi organism process GO:0043900 111 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
modification dependent protein catabolic process GO:0019941 133 0.019
early endosome to late endosome transport GO:0045022 2 0.019
apoptotic signaling pathway GO:0097190 306 0.019
glycerophospholipid biosynthetic process GO:0046474 32 0.019
protein modification by small protein conjugation GO:0032446 187 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
synaptic transmission GO:0007268 329 0.018
oocyte construction GO:0007308 2 0.018
oocyte axis specification GO:0007309 2 0.018
purine nucleotide biosynthetic process GO:0006164 65 0.018
organic hydroxy compound biosynthetic process GO:1901617 77 0.018
localization within membrane GO:0051668 4 0.018
regulation of cellular amino acid metabolic process GO:0006521 5 0.018
cation homeostasis GO:0055080 212 0.018
development of primary sexual characteristics GO:0045137 143 0.018
maintenance of location GO:0051235 89 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
gonad development GO:0008406 141 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
nucleoside biosynthetic process GO:0009163 21 0.018
regulation of homeostatic process GO:0032844 182 0.018
positive regulation of transferase activity GO:0051347 167 0.017
protein import GO:0017038 101 0.017
forebrain development GO:0030900 302 0.017
proteasomal protein catabolic process GO:0010498 98 0.017
water soluble vitamin biosynthetic process GO:0042364 3 0.017
regulation of metal ion transport GO:0010959 106 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
mapk cascade GO:0000165 281 0.017
regulation of phospholipid biosynthetic process GO:0071071 3 0.017
response to oxygen levels GO:0070482 62 0.017
regulation of nucleocytoplasmic transport GO:0046822 73 0.017
protein folding GO:0006457 28 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
establishment of protein localization to organelle GO:0072594 118 0.017
spermatid development GO:0007286 108 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
single organism nuclear import GO:1902593 95 0.016
striated muscle tissue development GO:0014706 293 0.016
adult behavior GO:0030534 135 0.016
activation of cysteine type endopeptidase activity GO:0097202 27 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
regulation of transporter activity GO:0032409 57 0.016
cellularization GO:0007349 1 0.016
ribose phosphate biosynthetic process GO:0046390 59 0.016
cytoplasmic microtubule organization GO:0031122 14 0.016
monosaccharide metabolic process GO:0005996 106 0.016
translesion synthesis GO:0019985 1 0.016
nuclear import GO:0051170 95 0.016
ribonucleoside biosynthetic process GO:0042455 21 0.016
regulation of ras protein signal transduction GO:0046578 114 0.015
purine ribonucleoside biosynthetic process GO:0046129 19 0.015
leukocyte proliferation GO:0070661 172 0.015
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051439 1 0.015
telencephalon development GO:0021537 186 0.015
response to lipopolysaccharide GO:0032496 128 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
retrograde transport endosome to golgi GO:0042147 2 0.015
thermosensory behavior GO:0040040 1 0.015
regulation of hormone levels GO:0010817 211 0.015
regulation of protein maturation GO:1903317 96 0.015
regulation of protein kinase activity GO:0045859 232 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
organelle localization GO:0051640 179 0.015
male gamete generation GO:0048232 285 0.015
cellular calcium ion homeostasis GO:0006874 119 0.014
monocarboxylic acid biosynthetic process GO:0072330 61 0.014
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.014
centrosome separation GO:0051299 4 0.014
glycosyl compound biosynthetic process GO:1901659 21 0.014
regulation of cellular response to stress GO:0080135 159 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.014
rna interference GO:0016246 2 0.014
protein localization to nucleus GO:0034504 121 0.014
peptide hormone secretion GO:0030072 109 0.014
cell division GO:0051301 120 0.014
single organism cell adhesion GO:0098602 156 0.014
developmental maturation GO:0021700 193 0.013
axonogenesis GO:0007409 274 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
organelle assembly GO:0070925 177 0.013
nadh metabolic process GO:0006734 1 0.013
muscle cell differentiation GO:0042692 261 0.013
chromatin organization GO:0006325 206 0.013
cell type specific apoptotic process GO:0097285 268 0.013
negative regulation of intracellular transport GO:0032387 38 0.013
regulation of mitochondrion organization GO:0010821 27 0.013
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.013
organelle fission GO:0048285 170 0.013
purine nucleobase metabolic process GO:0006144 4 0.013
multicellular organismal aging GO:0010259 24 0.013
dicarboxylic acid metabolic process GO:0043648 18 0.013
glycolytic process GO:0006096 20 0.013
sequestering of metal ion GO:0051238 19 0.013
cellular response to lipid GO:0071396 145 0.013
organic acid transport GO:0015849 101 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
cellular component assembly involved in morphogenesis GO:0010927 139 0.013
cell maturation GO:0048469 127 0.013
negative regulation of alcohol biosynthetic process GO:1902931 4 0.012
cell growth GO:0016049 130 0.012
calcium ion transport GO:0006816 159 0.012
nucleobase containing compound transport GO:0015931 27 0.012
Yeast
glucose homeostasis GO:0042593 128 0.012
insulin secretion GO:0030073 89 0.012
regulation of cofactor metabolic process GO:0051193 5 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
cell substrate adhesion GO:0031589 130 0.012
extracellular structure organization GO:0043062 148 0.012
negative regulation of protein processing GO:0010955 79 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
regulation of cell cycle process GO:0010564 160 0.012
gland development GO:0048732 330 0.012
learning or memory GO:0007611 148 0.012
zymogen activation GO:0031638 41 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
regulation of cell adhesion GO:0030155 154 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
asymmetric stem cell division GO:0098722 3 0.012
heart morphogenesis GO:0003007 178 0.012
epithelial cell proliferation GO:0050673 174 0.012
canonical wnt signaling pathway GO:0060070 130 0.011
hexose metabolic process GO:0019318 98 0.011
purine ribonucleotide biosynthetic process GO:0009152 59 0.011
negative regulation of cytoplasmic transport GO:1903650 29 0.011
neural tube development GO:0021915 160 0.011
regulation of ion transmembrane transporter activity GO:0032412 54 0.011
pyridine containing compound catabolic process GO:0072526 4 0.011
response to light stimulus GO:0009416 135 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
smad protein complex assembly GO:0007183 1 0.011
spindle assembly involved in mitosis GO:0090307 4 0.011
hormone secretion GO:0046879 128 0.011
regulation of cell growth GO:0001558 91 0.011
anion transport GO:0006820 177 0.011
Yeast Fly
regulation of nuclear division GO:0051783 56 0.011
negative regulation of molecular function GO:0044092 258 0.011
oocyte differentiation GO:0009994 35 0.011
blood vessel morphogenesis GO:0048514 285 0.011
extracellular matrix organization GO:0030198 147 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
positive regulation of cell development GO:0010720 237 0.011
establishment of vesicle localization GO:0051650 81 0.011
carbohydrate homeostasis GO:0033500 128 0.011
small molecule catabolic process GO:0044282 71 0.011
negative regulation of multi organism process GO:0043901 68 0.011
sensory perception GO:0007600 245 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
amide transport GO:0042886 138 0.011
regulation of cell division GO:0051302 76 0.011
mitotic nuclear division GO:0007067 48 0.011
protein import into nucleus GO:0006606 95 0.011
anatomical structure homeostasis GO:0060249 145 0.011
hexose catabolic process GO:0019320 3 0.011
mitochondrial transport GO:0006839 36 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.011
glycerolipid metabolic process GO:0046486 122 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
regulation of kinase activity GO:0043549 249 0.011
ossification GO:0001503 216 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
oogenesis GO:0048477 56 0.011
regulation of protein import into nucleus GO:0042306 52 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
neuron death GO:0070997 154 0.011
organic anion transport GO:0015711 137 0.010
response to radiation GO:0009314 165 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
regulation of calcium ion transport GO:0051924 69 0.010
synapse organization GO:0050808 125 0.010
cellular response to inorganic substance GO:0071241 37 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
regulation of neuron differentiation GO:0045664 281 0.010
regulation of anatomical structure size GO:0090066 178 0.010
action potential GO:0001508 78 0.010
fatty acid biosynthetic process GO:0006633 41 0.010
phospholipid biosynthetic process GO:0008654 36 0.010
positive regulation of cell adhesion GO:0045785 80 0.010
pyridine nucleotide metabolic process GO:0019362 12 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.010

Vdac2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.059
disease of anatomical entity DOID:7 0 0.055
nervous system disease DOID:863 0 0.055
inherited metabolic disorder DOID:655 0 0.049
central nervous system disease DOID:331 0 0.028
neurodegenerative disease DOID:1289 0 0.028
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.015
sensory system disease DOID:0050155 0 0.011